ENILURACIL

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Synonyms
Status
Molecule Category Free-form
UNII 2E2W0W5XIU
EPA CompTox DTXSID10208696

Structure

InChI Key JOZGNYDSEBIJDH-UHFFFAOYSA-N
Smiles C#Cc1c[nH]c(=O)[nH]c1=O
InChI
InChI=1S/C6H4N2O2/c1-2-4-3-7-6(10)8-5(4)9/h1,3H,(H2,7,8,9,10)

Physicochemical Descriptors

Property Name Value
Molecular Formula C6H4N2O2
Molecular Weight 136.11
AlogP -0.13
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 2.0
Polar Surface Area 66.24
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 10.0

Pharmacology

Mechanism of Action Action Reference
Dihydropyrimidine dehydrogenase inhibitor INHIBITOR PubMed PubMed
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme
- 14 - - -

Target Conservation

Protein: Dihydropyrimidine dehydrogenase
Description: Dihydropyrimidine dehydrogenase [NADP(+)]
Organism : Homo sapiens
Q12882 ENSG00000188641

Cross References

Resources Reference
ChEMBL CHEMBL355200
DrugBank DB03516
FDA SRS 2E2W0W5XIU
PDB Y3G
PubChem 43157
SureChEMBL SCHEMBL37817
ZINC ZINC000000005467
CONTENTS