EcoDrugPlus


Synonyms	Chlorphenamine, (s)- Chlorpheniramine d-form Chlorpheniramine, (s)- Chlorpheniramine, d- Dapriton Dexchlorpheniramine
Status
Molecule Category	Free-form
ATC	R06AB02
UNII	3Q9Q0B929N
EPA CompTox	DTXSID50180225


InChI Key	SOYKEARSMXGVTM-HNNXBMFYSA-N
Smiles	CN(C)CC[C@@H](c1ccc(Cl)cc1)c1ccccn1
InChI	InChI=1S/C16H19ClN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3/t15-/m0/s1

Property Name	Value
Molecular Formula	C16H19ClN2
Molecular Weight	274.8
AlogP	3.82
Hydrogen Bond Acceptor	2.0
Number of Rotational Bond	5.0
Polar Surface Area	16.13
Molecular species	BASE
Aromatic Rings	2.0
Heavy Atoms	19.0

Resources	Reference
ChEBI	4464
ChEMBL	CHEMBL1201353
DrugBank	DB13679
DrugCentral	4411
FDA SRS	3Q9Q0B929N
Human Metabolome Database	HMDB0240218
Guide to Pharmacology	1210
KEGG	C06946
PubChem	33036
SureChEMBL	SCHEMBL3538
ZINC	ZINC000000113404

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

DEXCHLORPHENIRAMINE

Structure

Physicochemical Descriptors

Related Entries

Cross References