EcoDrugPlus


Synonyms	Cevimeline
Status
Molecule Category	Free-form
ATC	N07AX03
UNII	K9V0CDQ56E
EPA CompTox	DTXSID40274384

Synonyms

Cevimeline

Status

Molecule Category

Free-form

ATC

N07AX03

UNII

K9V0CDQ56E

EPA CompTox

DTXSID40274384


InChI Key	WUTYZMFRCNBCHQ-UHFFFAOYSA-N
Smiles	CC1OC2(CS1)CN1CCC2CC1
InChI	InChI=1S/C10H17NOS/c1-8-12-10(7-13-8)6-11-4-2-9(10)3-5-11/h8-9H,2-7H2,1H3

InChI Key

WUTYZMFRCNBCHQ-UHFFFAOYSA-N

Smiles

CC1OC2(CS1)CN1CCC2CC1

InChI

InChI=1S/C10H17NOS/c1-8-12-10(7-13-8)6-11-4-2-9(10)3-5-11/h8-9H,2-7H2,1H3

Property Name	Value
Molecular Formula	C10H17NOS
Molecular Weight	199.32
AlogP	1.56
Hydrogen Bond Acceptor	3.0
Polar Surface Area	12.47
Molecular species	BASE
Aromatic Rings	0.0
Heavy Atoms	13.0

Property Name

Value

Molecular Formula

C10H17NOS

Molecular Weight

199.32

AlogP

1.56

Hydrogen Bond Acceptor

3.0

Polar Surface Area

12.47

Molecular species

BASE

Aromatic Rings

0.0

Heavy Atoms

13.0

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Monoamine receptor Acetylcholine receptor	-	-	-	851.14	-

Targets

EC50(nM)

IC50(nM)

Kd(nM)

Ki(nM)

Inhibition(%)

Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Monoamine receptor Acetylcholine receptor

851.14

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Homo sapiens	-	-	-	851.14	-

EC50(nM)

IC50(nM)

Kd(nM)

Ki(nM)

Inhibition(%)

Homo sapiens

851.14

Resources	Reference
ChEMBL	CHEMBL168815
DrugCentral	584
FDA SRS	K9V0CDQ56E
Guide to Pharmacology	9658
PubChem	18642481
SureChEMBL	SCHEMBL299760

Resources

Reference

ChEMBL

CHEMBL168815

DrugCentral

584

FDA SRS

K9V0CDQ56E

Guide to Pharmacology

9658

PubChem

18642481

SureChEMBL

SCHEMBL299760

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

CEVIMELINE

Structure

Physicochemical Descriptors

Pharmacology

Cross References