| Synonyms | |
| Status | |
| Molecule Category | Free-form |
| UNII | U2Y5OFN795 |
| EPA CompTox | DTXSID20215295 |
Structure
| InChI Key | LTEJRLHKIYCEOX-OCCSQVGLSA-N |
|---|---|
| Smiles | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C22H24FN5O4 |
| Molecular Weight | 441.46 |
| AlogP | 3.42 |
| Hydrogen Bond Acceptor | 8.0 |
| Hydrogen Bond Donor | 2.0 |
| Number of Rotational Bond | 7.0 |
| Polar Surface Area | 116.76 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 4.0 |
| Heavy Atoms | 32.0 |
Pharmacology
Target Conservation
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Protein: Fibroblast growth factor receptor Description: Fibroblast growth factor receptor 1 Organism : Homo sapiens P11362 ENSG00000077782 |
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Protein: Vascular endothelial growth factor receptor Description: Vascular endothelial growth factor receptor 1 Organism : Homo sapiens P17948 ENSG00000102755 |
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Protein: Fibroblast growth factor receptor Description: Fibroblast growth factor receptor 2 Organism : Homo sapiens P21802 ENSG00000066468 |
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Protein: Fibroblast growth factor receptor Description: Fibroblast growth factor receptor 4 Organism : Homo sapiens P22455 ENSG00000160867 |
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Protein: Fibroblast growth factor receptor Description: Fibroblast growth factor receptor 3 Organism : Homo sapiens P22607 ENSG00000068078 |
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Protein: Vascular endothelial growth factor receptor Description: Vascular endothelial growth factor receptor 3 Organism : Homo sapiens P35916 ENSG00000037280 |
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Protein: Vascular endothelial growth factor receptor Description: Vascular endothelial growth factor receptor 2 Organism : Homo sapiens P35968 ENSG00000128052 |
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Related Entries
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 167656 |
| ChEMBL | CHEMBL270995 |
| DrugBank | DB11865 |
| FDA SRS | U2Y5OFN795 |
| Guide to Pharmacology | 8097 |
| PubChem | 11154925 |
| SureChEMBL | SCHEMBL483382 |
| ZINC | ZINC000029134440 |
CONTENTS
