BISACODYL

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Search structure


Synonyms	Biolax Bisacodyl Correctol tablets, caplets Dulcodos Dulcolax Entrolax Evac-q-tabs Feen-a-mint tablets Modane NSC-755914 Sk-bisacodyl Theralax
Status
Molecule Category	Free-form
ATC	A06AB02 A06AG02
UNII	10X0709Y6I
EPA CompTox	DTXSID1022681

Structure


InChI Key	KHOITXIGCFIULA-UHFFFAOYSA-N
Smiles	CC(=O)Oc1ccc(C(c2ccc(OC(C)=O)cc2)c2ccccn2)cc1
InChI	InChI=1S/C22H19NO4/c1-15(24)26-19-10-6-17(7-11-19)22(21-5-3-4-14-23-21)18-8-12-20(13-9-18)27-16(2)25/h3-14,22H,1-2H3

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C22H19NO4
Molecular Weight	361.4
AlogP	4.11
Hydrogen Bond Acceptor	5.0
Number of Rotational Bond	5.0
Polar Surface Area	65.49
Molecular species	NEUTRAL
Aromatic Rings	3.0
Heavy Atoms	27.0

Metabolites Network

visNetwork

Pharmacology

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides	-	-	-	-	97.08-103.27

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Cricetulus griseus	-	-	-	-	97.08-103.27

Cross References

Resources	Reference
ChEBI	3125
ChEMBL	CHEMBL942
DrugBank	DB09020
DrugCentral	375
FDA SRS	10X0709Y6I
PubChem	2391
SureChEMBL	SCHEMBL21044
ZINC	ZINC000003830321

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025