EcoDrugPlus


Synonyms	Benserazide Benserazide (as hydrochloride) Benserazide hcl Benserazide hydrochloride NSC-755907 RO 4-4602 RO-4-4602 Serazide
Status
Molecule Category	Free-form
UNII	762OS3ZEJU
EPA CompTox	DTXSID9022651

Synonyms

Benserazide

Benserazide (as hydrochloride)

Benserazide hcl

Benserazide hydrochloride

NSC-755907

RO 4-4602

RO-4-4602

Serazide

Status

Molecule Category

Free-form

UNII

762OS3ZEJU

EPA CompTox

DTXSID9022651


InChI Key	BNQDCRGUHNALGH-UHFFFAOYSA-N
Smiles	NC(CO)C(=O)NNCc1ccc(O)c(O)c1O
InChI	InChI=1S/C10H15N3O5/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16/h1-2,6,12,14-17H,3-4,11H2,(H,13,18)

InChI Key

BNQDCRGUHNALGH-UHFFFAOYSA-N

Smiles

NC(CO)C(=O)NNCc1ccc(O)c(O)c1O

InChI

InChI=1S/C10H15N3O5/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16/h1-2,6,12,14-17H,3-4,11H2,(H,13,18)

Property Name	Value
Molecular Formula	C10H15N3O5
Molecular Weight	257.25
AlogP	-1.76
Hydrogen Bond Acceptor	7.0
Hydrogen Bond Donor	7.0
Number of Rotational Bond	5.0
Polar Surface Area	148.07
Molecular species	NEUTRAL
Aromatic Rings	1.0
Heavy Atoms	18.0

Property Name

Value

Molecular Formula

C10H15N3O5

Molecular Weight

257.25

AlogP

-1.76

Hydrogen Bond Acceptor

7.0

Hydrogen Bond Donor

7.0

Number of Rotational Bond

5.0

Polar Surface Area

148.07

Molecular species

NEUTRAL

Aromatic Rings

1.0

Heavy Atoms

18.0

Mechanism of Action	Action	Reference
DOPA decarboxylase inhibitor	INHIBITOR	PubMed PubMed PubMed PubMed

Mechanism of Action

Action

Reference

DOPA decarboxylase inhibitor

INHIBITOR

PubMed PubMed PubMed PubMed

Resources	Reference
ChEBI	64187
ChEMBL	CHEMBL1096979
DrugBank	DB12783
DrugCentral	314
FDA SRS	762OS3ZEJU
Guide to Pharmacology	5150
PharmGKB	PA165360203
PubChem	2327
SureChEMBL	SCHEMBL34522

Resources

Reference

ChEBI

ChEMBL

DrugBank

DrugCentral

FDA SRS

Guide to Pharmacology

PharmGKB

PubChem

SureChEMBL

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

BENSERAZIDE

Structure

Physicochemical Descriptors

Pharmacology

Cross References