BELORANIB

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Synonyms
Status
Molecule Category Free-form
UNII FI471K8BU6
EPA CompTox DTXSID40179800

Structure

InChI Key ZEZFKUBILQRZCK-MJSCXXSSSA-N
Smiles CO[C@@H]1[C@H](OC(=O)/C=C/c2ccc(OCCN(C)C)cc2)CC[C@]2(CO2)[C@H]1[C@@]1(C)O[C@@H]1CC=C(C)C
InChI
InChI=1S/C29H41NO6/c1-20(2)7-13-24-28(3,36-24)27-26(32-6)23(15-16-29(27)19-34-29)35-25(31)14-10-21-8-11-22(12-9-21)33-18-17-30(4)5/h7-12,14,23-24,26-27H,13,15-19H2,1-6H3/b14-10+/t23-,24-,26-,27-,28+,29+/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C29H41NO6
Molecular Weight 499.65
AlogP 4.26
Hydrogen Bond Acceptor 7.0
Number of Rotational Bond 11.0
Polar Surface Area 73.06
Molecular species BASE
Aromatic Rings 1.0
Heavy Atoms 36.0

Pharmacology

Mechanism of Action Action Reference
Methionine aminopeptidase 2 inhibitor INHIBITOR PubMed PubMed

Target Conservation

Protein: Methionine aminopeptidase 2
Description: Methionine aminopeptidase 2
Organism : Homo sapiens
P50579 ENSG00000111142

Cross References

Resources Reference
ChEMBL CHEMBL4297504
DrugBank DB12671
FDA SRS FI471K8BU6
Guide to Pharmacology 8445
PubChem 6918502
SureChEMBL SCHEMBL14648763
ZINC ZINC000003982162
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