AV-101

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Synonyms
Status
Molecule Category Free-form
UNII 77XLH9L40B

Structure

InChI Key HQLHZNDJQSRKDT-UHFFFAOYSA-N
Smiles Nc1cc(Cl)ccc1C(=O)CC(N)C(=O)O
InChI
InChI=1S/C10H11ClN2O3/c11-5-1-2-6(7(12)3-5)9(14)4-8(13)10(15)16/h1-3,8H,4,12-13H2,(H,15,16)

Physicochemical Descriptors

Property Name Value
Molecular Formula C10H11ClN2O3
Molecular Weight 242.66
AlogP 0.91
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 4.0
Polar Surface Area 106.41
Molecular species ZWITTERION
Aromatic Rings 1.0
Heavy Atoms 16.0

Pharmacology

Mechanism of Action Action Reference
Glutamate [NMDA] receptor antagonist ANTAGONIST Wikipedia Other PubMed

Target Conservation

Protein: Glutamate [NMDA] receptor
Description: Glutamate receptor ionotropic, NMDA 2D
Organism : Homo sapiens
O15399 ENSG00000105464
Protein: Glutamate [NMDA] receptor
Description: Glutamate receptor ionotropic, NMDA 3B
Organism : Homo sapiens
O60391 ENSG00000116032
Protein: Glutamate [NMDA] receptor
Description: Glutamate receptor ionotropic, NMDA 1
Organism : Homo sapiens
Q05586 ENSG00000176884
Protein: Glutamate [NMDA] receptor
Description: Glutamate receptor ionotropic, NMDA 2A
Organism : Homo sapiens
Q12879 ENSG00000183454
Protein: Glutamate [NMDA] receptor
Description: Glutamate receptor ionotropic, NMDA 2B
Organism : Homo sapiens
Q13224 ENSG00000273079
Protein: Glutamate [NMDA] receptor
Description: Glutamate receptor ionotropic, NMDA 2C
Organism : Homo sapiens
Q14957 ENSG00000161509
Protein: Glutamate [NMDA] receptor
Description: Glutamate receptor ionotropic, NMDA 3A
Organism : Homo sapiens
Q8TCU5 ENSG00000198785

Related Entries

Cross References

Resources Reference
ChEMBL CHEMBL3545351
FDA SRS 77XLH9L40B
PubChem 9859632
SureChEMBL SCHEMBL5286788
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