EcoDrugPlus


Trade Names	CYKLOKAPRON LYSTEDA TRANEXAMIC ACID
Synonyms	Amcha CL 65336 CL-65336 Cyclo-f Cyclocapron Cyclokapron Cyklo-f heavy period relief Cyklokapron Espercil Exacyl Femstrual Haematrix LB-1148 LB1148 Lysteda
Status
Molecule Category	Free-form
ATC	B02AA02
UNII	6T84R30KC1

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SubStructure

Threshold (%) >= 70


InChI Key	GYDJEQRTZSCIOI-LJGSYFOKSA-N
Smiles	NC[C@H]1CC[C@H](C(=O)O)CC1
InChI	InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C8H15NO2
Molecular Weight	157.21
AlogP	0.84
Hydrogen Bond Acceptor	2.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	2.0
Polar Surface Area	63.32
Molecular species	ZWITTERION
Aromatic Rings	0.0
Heavy Atoms	11.0

Mechanism of Action	Action	Reference
Plasminogen inhibitor	INHIBITOR	DailyMed

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Enzyme Protease Serine protease Serine protease PA clan Serine protease S1A subfamily	-	-	-	-	9.5
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides	-	-	-	-	81.79-102.32

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Cricetulus griseus	-	-	-	-	81.79-102.32
Homo sapiens	-	-	-	-	9.5

Target Conservation


Protein: Plasminogen Description: Plasminogen Organism : Homo sapiens P00747 ENSG00000122194

Cross References

Resources	Reference
ChEBI	48669
ChEMBL	CHEMBL877
DrugBank	DB00302
DrugCentral	2713
FDA SRS	6T84R30KC1
Human Metabolome Database	HMDB0014447
Guide to Pharmacology	6573
KEGG	C12535
PDB	AMH
SureChEMBL	SCHEMBL16974
ZINC	ZINC000100071256

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

TRANEXAMIC ACID

Structure

Physicochemical Descriptors

Pharmacology

Target Conservation

Related Entries

Cross References