EcoDrugPlus


Trade Names	TINDAMAX TINIDAZOLE
Synonyms	CP-12,574 CP-12574 Fasigin Fasigyn Haisigyn NSC-758189 Symplotan Tindamax Tinidazole Tricolam Trimonase
Status
Molecule Category	Free-form
ATC	J01XD02 P01AB02
UNII	033KF7V46H
EPA CompTox	DTXSID4023676


InChI Key	HJLSLZFTEKNLFI-UHFFFAOYSA-N
Smiles	CCS(=O)(=O)CCn1c([N+](=O)[O-])cnc1C
InChI	InChI=1S/C8H13N3O4S/c1-3-16(14,15)5-4-10-7(2)9-6-8(10)11(12)13/h6H,3-5H2,1-2H3

Property Name	Value
Molecular Formula	C8H13N3O4S
Molecular Weight	247.28
AlogP	0.53
Hydrogen Bond Acceptor	6.0
Number of Rotational Bond	5.0
Polar Surface Area	95.1
Molecular species	NEUTRAL
Aromatic Rings	1.0
Heavy Atoms	16.0

Mechanism of Action	Action	Reference
DNA inhibitor	INHIBITOR	DailyMed

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides	-	-	-	-	87.04-99.37
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC22 family of organic cation and anion transporters	-	-	-	-	14.2

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Cricetulus griseus	-	-	-	-	87.04-99.37
Giardia intestinalis	-	300-300	-	-	-
Homo sapiens	-	-	-	-	14.2

Resources	Reference
ChEBI	63627
ChEMBL	CHEMBL1220
DrugBank	DB00911
DrugCentral	2671
FDA SRS	033KF7V46H
Human Metabolome Database	HMDB0015047
PharmGKB	PA10813
PubChem	5479
SureChEMBL	SCHEMBL21141
ZINC	ZINC000000113446

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

TINIDAZOLE

Structure

Physicochemical Descriptors

Pharmacology

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