TENOFOVIR ALAFENAMIDE FUMARATE

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Trade Names
Synonyms
Status
Molecule Category Mixture
UNII FWF6Q91TZO

Structure

InChI Key SVUJNSGGPUCLQZ-FQQAACOVSA-N
Smiles CC(C)OC(=O)[C@H](C)N[P@](=O)(CO[C@H](C)Cn1cnc2c(N)ncnc21)Oc1ccccc1.CC(C)OC(=O)[C@H](C)N[P@](=O)(CO[C@H](C)Cn1cnc2c(N)ncnc21)Oc1ccccc1.O=C(O)/C=C/C(=O)O
InChI
InChI=1S/2C21H29N6O5P.C4H4O4/c2*1-14(2)31-21(28)16(4)26-33(29,32-17-8-6-5-7-9-17)13-30-15(3)10-27-12-25-18-19(22)23-11-24-20(18)27;5-3(6)1-2-4(7)8/h2*5-9,11-12,14-16H,10,13H2,1-4H3,(H,26,29)(H2,22,23,24);1-2H,(H,5,6)(H,7,8)/b;;2-1+/t2*15-,16+,33+;/m11./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C46H62N12O14P2
Molecular Weight 1069.02
AlogP 2.97
Hydrogen Bond Acceptor 10.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 11.0
Polar Surface Area 143.48
Molecular species NEUTRAL
Aromatic Rings 3.0
Heavy Atoms 33.0

Pharmacology

Mechanism of Action Action Reference
Human immunodeficiency virus type 1 reverse transcriptase inhibitor INHIBITOR DailyMed

Cross References

Resources Reference
ChEBI 90923
ChEMBL CHEMBL2364637
FDA SRS FWF6Q91TZO
PubChem 71511838
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