EcoDrugPlus


Trade Names	ARAKODA KRINTAFEL
Synonyms	Arakoda Krintafel SB-252263-AX Tafenoquine succinate WR-238605
Status
Molecule Category	Salt-form
UNII	DL5J0B8VSS
Parent Compound:	TAFENOQUINE

Trade Names

ARAKODA

KRINTAFEL

Synonyms

Arakoda

Krintafel

SB-252263-AX

Tafenoquine succinate

WR-238605

Status

Molecule Category

Salt-form

UNII

DL5J0B8VSS

Parent Compound:

TAFENOQUINE


InChI Key	CQBKFGJRAOXYIP-UHFFFAOYSA-N
Smiles	COc1cc(C)c2c(Oc3cccc(C(F)(F)F)c3)c(OC)cc(NC(C)CCCN)c2n1.O=C(O)CCC(=O)O
InChI	InChI=1S/C24H28F3N3O3.C4H6O4/c1-14-11-20(32-4)30-22-18(29-15(2)7-6-10-28)13-19(31-3)23(21(14)22)33-17-9-5-8-16(12-17)24(25,26)27;5-3(6)1-2-4(7)8/h5,8-9,11-13,15,29H,6-7,10,28H2,1-4H3;1-2H2,(H,5,6)(H,7,8)

InChI Key

CQBKFGJRAOXYIP-UHFFFAOYSA-N

Smiles

COc1cc(C)c2c(Oc3cccc(C(F)(F)F)c3)c(OC)cc(NC(C)CCCN)c2n1.O=C(O)CCC(=O)O

InChI

InChI=1S/C24H28F3N3O3.C4H6O4/c1-14-11-20(32-4)30-22-18(29-15(2)7-6-10-28)13-19(31-3)23(21(14)22)33-17-9-5-8-16(12-17)24(25,26)27;5-3(6)1-2-4(7)8/h5,8-9,11-13,15,29H,6-7,10,28H2,1-4H3;1-2H2,(H,5,6)(H,7,8)

Property Name	Value
Molecular Formula	C28H34F3N3O7
Molecular Weight	581.59
AlogP	5.91
Hydrogen Bond Acceptor	6.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	9.0
Polar Surface Area	78.63
Molecular species	BASE
Aromatic Rings	3.0
Heavy Atoms	33.0

Property Name

Value

Molecular Formula

C28H34F3N3O7

Molecular Weight

581.59

AlogP

5.91

Hydrogen Bond Acceptor

6.0

Hydrogen Bond Donor

2.0

Number of Rotational Bond

9.0

Polar Surface Area

78.63

Molecular species

BASE

Aromatic Rings

3.0

Heavy Atoms

33.0

Resources	Reference
ChEMBL	CHEMBL2364635
FDA SRS	DL5J0B8VSS
PubChem	163761
SureChEMBL	SCHEMBL1004186

Resources

Reference

ChEMBL

FDA SRS

PubChem

SureChEMBL

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025

TAFENOQUINE SUCCINATE

Structure

Physicochemical Descriptors

Cross References