SULFANILAMIDE

/static/temp/default.svg Search structure
Trade Names
Synonyms
Status
Molecule Category Free-form
ATC D06BA05 J01EB06
UNII 21240MF57M
EPA CompTox DTXSID4023622

Structure

InChI Key FDDDEECHVMSUSB-UHFFFAOYSA-N
Smiles Nc1ccc(S(N)(=O)=O)cc1
InChI
InChI=1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)

Physicochemical Descriptors

Property Name Value
Molecular Formula C6H8N2O2S
Molecular Weight 172.21
AlogP -0.08
Hydrogen Bond Acceptor 3.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 1.0
Polar Surface Area 86.18
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 11.0

Pharmacology

Mechanism of Action Action Reference
Bacterial dihydropteroate synthase inhibitor INHIBITOR PubMed PubMed PubMed
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Cytochrome P450 Cytochrome P450 family 2 Cytochrome P450 family 2C Cytochrome P450 2C9
- - - -
Enzyme Hydrolase
- - - - 5.19-10.19
Enzyme Lyase
- 256-298 - 32-988 -
Enzyme
- 256-298 - 32-988 5.19-10.19
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides
- - - - 113.76-155.79
EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Anopheles gambiae
- - - 862 -
Bos taurus
- - - 851.14 -
Colwellia psychrerythraea
- - - 867 -
Cricetulus griseus
- - - - 113.76-155.79
Cryptococcus neoformans
- - - 765-770 -
Enterobacter sp.
- - - 583 -
Helicobacter pylori
- - - 240-454 -
Homo sapiens
- 80-298 - 32-988 -17.8-10.19
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
- - - 277-946 -
Leishmania donovani chagasi
- - - 250 -
Malassezia globosa CBS 7966
- - - 245 -
Methanosarcina thermophila
- - - 250-250 -
Mus musculus
- - - 32 -
Nostoc commune
- - - 488-488 -
Plasmodium falciparum
- - - 808 -
Porphyromonas gingivalis
- - - 715-893 -
Rattus norvegicus
- - - - 10
Stylophora pistillata
- - - 300-364 -
Sulfurihydrogenibium yellowstonense
- - - 652-803 -
Thalassiosira weissflogii
- - - 181 -
Thiomicrospira crunogena XCL-2
- - - 628 -
Vibrio cholerae
- - - 68-471 -

Environmental Exposure

Environmental Exposure Map
Countries
Vietnam

Cross References

Resources Reference
ChEBI 45373
ChEMBL CHEMBL21
DrugBank DB00259
DrugCentral 2521
FDA SRS 21240MF57M
Human Metabolome Database HMDB0014404
KEGG C07458
PDB SAN
PharmGKB PA451545
PubChem 5333
SureChEMBL SCHEMBL740
ZINC ZINC000000002101
CONTENTS