STREPTOZOCIN

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Trade Names
Synonyms
STZ
Status
Molecule Category Free-form
ATC L01AD04
UNII 5W494URQ81
EPA CompTox DTXSID90369855

Structure

InChI Key ZSJLQEPLLKMAKR-YDEIVXIUSA-N
Smiles CN(N=O)C(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
InChI
InChI=1S/C8H15N3O7/c1-11(10-17)8(16)9-4-6(14)5(13)3(2-12)18-7(4)15/h3-7,12-15H,2H2,1H3,(H,9,16)/t3-,4-,5-,6-,7?/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C8H15N3O7
Molecular Weight 265.22
AlogP -2.89
Hydrogen Bond Acceptor 8.0
Hydrogen Bond Donor 5.0
Number of Rotational Bond 3.0
Polar Surface Area 151.92
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 18.0

Pharmacology

Mechanism of Action Action Reference
DNA inhibitor INHIBITOR DailyMed Wikipedia
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides
- - - - 93.43-100.3
EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Cricetulus griseus
- - - - 93.43-100.3

Related Entries

Cross References

Resources Reference
ChEMBL CHEMBL1651906
DrugCentral 2483
FDA SRS 5W494URQ81
PubChem 23615975
SureChEMBL SCHEMBL444088
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