EcoDrugPlus


Trade Names	ERTACZO
Synonyms	Dermofix Dermovit Ertaczo FI 7056 FI-7056 Sertaconazole mononitrate Sertaconazole nitrate Zalain
Status
Molecule Category	Salt-form
UNII	1DV05410M5
EPA CompTox	DTXSID2045529

Trade Names

ERTACZO

Synonyms

Dermofix

Dermovit

Ertaczo

FI 7056

FI-7056

Sertaconazole mononitrate

Sertaconazole nitrate

Zalain

Status

Molecule Category

Salt-form

UNII

1DV05410M5

EPA CompTox

DTXSID2045529


InChI Key	HAAITRDZHUANGT-UHFFFAOYSA-N
Smiles	Clc1ccc(C(Cn2ccnc2)OCc2csc3c(Cl)cccc23)c(Cl)c1.O=[N+]([O-])O
InChI	InChI=1S/C20H15Cl3N2OS.HNO3/c21-14-4-5-16(18(23)8-14)19(9-25-7-6-24-12-25)26-10-13-11-27-20-15(13)2-1-3-17(20)22;2-1(3)4/h1-8,11-12,19H,9-10H2;(H,2,3,4)

InChI Key

HAAITRDZHUANGT-UHFFFAOYSA-N

Smiles

Clc1ccc(C(Cn2ccnc2)OCc2csc3c(Cl)cccc23)c(Cl)c1.O=[N+]([O-])O

InChI

InChI=1S/C20H15Cl3N2OS.HNO3/c21-14-4-5-16(18(23)8-14)19(9-25-7-6-24-12-25)26-10-13-11-27-20-15(13)2-1-3-17(20)22;2-1(3)4/h1-8,11-12,19H,9-10H2;(H,2,3,4)

Property Name	Value
Molecular Formula	C20H16Cl3N3O4S
Molecular Weight	500.79
AlogP	7.02
Hydrogen Bond Acceptor	4.0
Number of Rotational Bond	6.0
Polar Surface Area	27.05
Molecular species	NEUTRAL
Aromatic Rings	4.0
Heavy Atoms	27.0

Property Name

Value

Molecular Formula

C20H16Cl3N3O4S

Molecular Weight

500.79

AlogP

7.02

Hydrogen Bond Acceptor

4.0

Number of Rotational Bond

6.0

Polar Surface Area

27.05

Molecular species

NEUTRAL

Aromatic Rings

4.0

Heavy Atoms

27.0

Mechanism of Action	Action	Reference
Cytochrome P450 51 inhibitor	INHIBITOR	FDA

Mechanism of Action

Action

Reference

Cytochrome P450 51 inhibitor

INHIBITOR

FDA

Resources	Reference
ChEMBL	CHEMBL1200725
FDA SRS	1DV05410M5
PubChem	200103
SureChEMBL	SCHEMBL261807

Resources

Reference

ChEMBL

FDA SRS

PubChem

SureChEMBL

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025

SERTACONAZOLE NITRATE

Structure

Physicochemical Descriptors

Pharmacology

Cross References