REVEFENACIN

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Trade Names
Synonyms
Status
Molecule Category Free-form
ATC R03BB08
UNII G2AE2VE07O

Structure

InChI Key FYDWDCIFZSGNBU-UHFFFAOYSA-N
Smiles CN(CCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1)C(=O)c1ccc(CN2CCC(C(N)=O)CC2)cc1
InChI
InChI=1S/C35H43N5O4/c1-38(34(42)29-13-11-26(12-14-29)25-40-19-15-28(16-20-40)33(36)41)23-24-39-21-17-30(18-22-39)44-35(43)37-32-10-6-5-9-31(32)27-7-3-2-4-8-27/h2-14,28,30H,15-25H2,1H3,(H2,36,41)(H,37,43)

Physicochemical Descriptors

Property Name Value
Molecular Formula C35H43N5O4
Molecular Weight 597.76
AlogP 4.84
Hydrogen Bond Acceptor 6.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 10.0
Polar Surface Area 108.21
Molecular species BASE
Aromatic Rings 3.0
Heavy Atoms 44.0

Pharmacology

Mechanism of Action Action Reference
Muscarinic acetylcholine receptor M3 antagonist ANTAGONIST FDA

Target Conservation

Protein: Muscarinic acetylcholine receptor M3
Description: Muscarinic acetylcholine receptor M3
Organism : Homo sapiens
P20309 ENSG00000133019

Cross References

Resources Reference
ChEMBL CHEMBL3833319
DrugBank DB11855
DrugCentral 5303
FDA SRS G2AE2VE07O
Guide to Pharmacology 10129
PubChem 11753673
SureChEMBL SCHEMBL356480
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