RANITIDINE HYDROCHLORIDE

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Search structure


Trade Names	RANITIDINE HYDROCHLORIDE ZANTAC ZANTAC 150 ZANTAC 25 ZANTAC 300 ZANTAC 75 ZANTAC IN PLASTIC CONTAINER
Synonyms	AH 19065 AH-19065 Azantac Dumoran Gavilast Gavilast-p Histac Raciran 150 Raciran 300 Ranicalm Raniplex Ranitic Ranitidine hcl Ranitidine hydrochloride Ranitil
Status
Molecule Category	Salt-form
UNII	BK76465IHM
Parent Compound:	RANITIDINE

Structure


InChI Key	GGWBHVILAJZWKJ-UHFFFAOYSA-N
Smiles	CNC(=C[N+](=O)[O-])NCCSCc1ccc(CN(C)C)o1.Cl
InChI	InChI=1S/C13H22N4O3S.ClH/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3;/h4-5,9,14-15H,6-8,10H2,1-3H3;1H

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C13H23ClN4O3S
Molecular Weight	350.87
AlogP	1.46
Hydrogen Bond Acceptor	7.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	10.0
Polar Surface Area	83.58
Molecular species	NEUTRAL
Aromatic Rings	1.0
Heavy Atoms	21.0

Pharmacology

Mechanism of Action	Action	Reference
Histamine H2 receptor antagonist	ANTAGONIST	FDA

Target Conservation


Protein: Histamine H2 receptor Description: Histamine H2 receptor Organism : Homo sapiens P25021 ENSG00000113749

Cross References

Resources	Reference
ChEMBL	CHEMBL2110372
FDA SRS	BK76465IHM
PubChem	47909

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025