| Trade Names | |
| Synonyms | |
| Status | |
| Molecule Category | Salt-form |
| UNII | 44665V00O8 |
| EPA CompTox | DTXSID8046951 |
| Parent Compound: | PROTRIPTYLINE |
Structure
| InChI Key | OGQDIIKRQRZXJH-UHFFFAOYSA-N |
|---|---|
| Smiles | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C19H22ClN |
| Molecular Weight | 299.85 |
| AlogP | 4.3 |
| Hydrogen Bond Acceptor | 1.0 |
| Hydrogen Bond Donor | 1.0 |
| Number of Rotational Bond | 4.0 |
| Polar Surface Area | 12.03 |
| Molecular species | BASE |
| Aromatic Rings | 2.0 |
| Heavy Atoms | 20.0 |
Pharmacology
| Mechanism of Action | Action | Reference |
|---|---|---|
| Norepinephrine transporter inhibitor | INHIBITOR | PubMed |
Target Conservation
|
Protein: Norepinephrine transporter Description: Sodium-dependent noradrenaline transporter Organism : Homo sapiens P23975 ENSG00000103546 |
|
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|
Protein: Serotonin transporter Description: Sodium-dependent serotonin transporter Organism : Homo sapiens P31645 ENSG00000108576 |
|
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Cross References
| Resources | Reference |
|---|---|
| ChEBI | 8598 |
| ChEMBL | CHEMBL1200332 |
| FDA SRS | 44665V00O8 |
| Guide to Pharmacology | 7285 |
| KEGG | C07408 |
| PubChem | 14667 |
| SureChEMBL | SCHEMBL119341 |
| ZINC | ZINC01530764 |
CONTENTS
