PROTOKYLOL HYDROCHLORIDE

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Search structure


Trade Names	VENTAIRE
Synonyms	NSC-113490 Protokylol HCl Protokylol hcl Protokylol hydrochloride Ventaire
Status
Molecule Category	Salt-form
UNII	7U7O8Q48IO

Structure


InChI Key	LOVXREQUMZKFCM-UHFFFAOYSA-N
Smiles	CC(Cc1ccc2c(c1)OCO2)NCC(O)c1ccc(O)c(O)c1.Cl
InChI	InChI=1S/C18H21NO5.ClH/c1-11(6-12-2-5-17-18(7-12)24-10-23-17)19-9-16(22)13-3-4-14(20)15(21)8-13;/h2-5,7-8,11,16,19-22H,6,9-10H2,1H3;1H

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C18H22ClNO5
Molecular Weight	367.83
AlogP	2.08
Hydrogen Bond Acceptor	6.0
Hydrogen Bond Donor	4.0
Number of Rotational Bond	6.0
Polar Surface Area	91.18
Molecular species	BASE
Aromatic Rings	2.0
Heavy Atoms	24.0

Pharmacology

Mechanism of Action	Action	Reference
Beta-2 adrenergic receptor agonist	AGONIST	PubMed

Target Conservation


Protein: Beta-2 adrenergic receptor Description: Beta-2 adrenergic receptor Organism : Homo sapiens P07550 ENSG00000169252

Cross References

Resources	Reference
ChEMBL	CHEMBL1200893
FDA SRS	7U7O8Q48IO
PubChem	8699
SureChEMBL	SCHEMBL210099

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025