PITAVASTATIN SODIUM

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Trade Names
Synonyms
Status
Molecule Category Salt-form
UNII 29556RBN9P
Parent Compound: PITAVASTATIN

Structure

InChI Key NBDQGOCGYHMDSJ-NRFPMOEYSA-M
Smiles O=C([O-])C[C@H](O)C[C@H](O)/C=C/c1c(C2CC2)nc2ccccc2c1-c1ccc(F)cc1.[Na+]
InChI
InChI=1S/C25H24FNO4.Na/c26-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-18(28)13-19(29)14-23(30)31;/h1-4,7-12,16,18-19,28-29H,5-6,13-14H2,(H,30,31);/q;+1/p-1/b12-11+;/t18-,19-;/m1./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C25H23FNNaO4
Molecular Weight 443.45
AlogP 4.52
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 8.0
Polar Surface Area 90.65
Molecular species ACID
Aromatic Rings 3.0
Heavy Atoms 31.0

Pharmacology

Mechanism of Action Action Reference
HMG-CoA reductase inhibitor INHIBITOR FDA

Target Conservation

Protein: HMG-CoA reductase
Description: 3-hydroxy-3-methylglutaryl-coenzyme A reductase
Organism : Homo sapiens
P04035 ENSG00000113161

Cross References

Resources Reference
ChEMBL CHEMBL3989920
FDA SRS 29556RBN9P
PubChem 23696934
SureChEMBL SCHEMBL15309107
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