PHENSUXIMIDE

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Search structure


Trade Names	MILONTIN
Synonyms	1-methyl-3-phenylsuccinimide Epimid Lifene Milontin Milonton Mirontin NSC-760079 PM-334 Phensuximid Phensuximide Racemic phensuximide Succitimal
Status
Molecule Category	Free-form
ATC	N03AD02
UNII	6WVL9C355G
EPA CompTox	DTXSID4023460

Structure


InChI Key	WLWFNJKHKGIJNW-UHFFFAOYSA-N
Smiles	CN1C(=O)CC(c2ccccc2)C1=O
InChI	InChI=1S/C11H11NO2/c1-12-10(13)7-9(11(12)14)8-5-3-2-4-6-8/h2-6,9H,7H2,1H3

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C11H11NO2
Molecular Weight	189.21
AlogP	1.16
Hydrogen Bond Acceptor	2.0
Number of Rotational Bond	1.0
Polar Surface Area	37.38
Molecular species	NEUTRAL
Aromatic Rings	1.0
Heavy Atoms	14.0

Pharmacology

Mechanism of Action	Action	Reference
Voltage-gated T-type calcium channel blocker	BLOCKER	PubMed

Cross References

Resources	Reference
ChEBI	8079
ChEMBL	CHEMBL797
DrugBank	DB00832
DrugCentral	2139
FDA SRS	6WVL9C355G
Human Metabolome Database	HMDB0014970
Guide to Pharmacology	7612
KEGG	C07437
PharmGKB	PA164771230
PubChem	6839
SureChEMBL	SCHEMBL35333

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025