EcoDrugPlus


Trade Names	XEPI
Synonyms	GF-001001-00 Gf-001001-00 Ozenoxacin T-3912 Xepi
Status
Molecule Category	Free-form
ATC	D06AX14
UNII	V0LH498RFO

Trade Names

XEPI

Synonyms

GF-001001-00

Gf-001001-00

Ozenoxacin

T-3912

Xepi

Status

Molecule Category

Free-form

ATC

D06AX14

UNII

V0LH498RFO


InChI Key	XPIJWUTXQAGSLK-UHFFFAOYSA-N
Smiles	CNc1ncc(-c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2C)cc1C
InChI	InChI=1S/C21H21N3O3/c1-11-8-13(9-23-20(11)22-3)15-6-7-16-18(12(15)2)24(14-4-5-14)10-17(19(16)25)21(26)27/h6-10,14H,4-5H2,1-3H3,(H,22,23)(H,26,27)

InChI Key

XPIJWUTXQAGSLK-UHFFFAOYSA-N

Smiles

CNc1ncc(-c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2C)cc1C

InChI

InChI=1S/C21H21N3O3/c1-11-8-13(9-23-20(11)22-3)15-6-7-16-18(12(15)2)24(14-4-5-14)10-17(19(16)25)21(26)27/h6-10,14H,4-5H2,1-3H3,(H,22,23)(H,26,27)

Property Name	Value
Molecular Formula	C21H21N3O3
Molecular Weight	363.42
AlogP	3.76
Hydrogen Bond Acceptor	5.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	4.0
Polar Surface Area	84.22
Molecular species	ACID
Aromatic Rings	3.0
Heavy Atoms	27.0

Property Name

Value

Molecular Formula

C21H21N3O3

Molecular Weight

363.42

AlogP

3.76

Hydrogen Bond Acceptor

5.0

Hydrogen Bond Donor

2.0

Number of Rotational Bond

4.0

Polar Surface Area

84.22

Molecular species

ACID

Aromatic Rings

3.0

Heavy Atoms

27.0

Mechanism of Action	Action	Reference
DNA gyrase inhibitor	INHIBITOR	FDA

Mechanism of Action

Action

Reference

DNA gyrase inhibitor

INHIBITOR

FDA

Resources	Reference
ChEBI	136050
ChEMBL	CHEMBL3990047
DrugBank	DB12924
DrugCentral	5058
FDA SRS	V0LH498RFO
Guide to Pharmacology	10841
PubChem	9863827
SureChEMBL	SCHEMBL1711829
ZINC	ZINC000001483896

Resources

Reference

ChEBI

ChEMBL

DrugBank

DrugCentral

FDA SRS

Guide to Pharmacology

PubChem

SureChEMBL

ZINC

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

OZENOXACIN

Structure

Physicochemical Descriptors

Pharmacology

Cross References