NITROUS OXIDE


Trade Names	NITROUS OXIDE, USP
Synonyms	Dinitrogen monoxide Dinitrogen oxide Dinitrogenii oxidum E-942 Entonox FEMA NO. 2779 Factitious air INS NO.942 INS-942 Laughing gas Nitrogen monoxide Nitrogen oxide (n(sub 2)o) Nitrogen protoxide Nitrogenum oxygenatum Nitrous Oxide Nitrous oxide Protoxide of nitrogen
Status
Molecule Category	UNKNOWN
ATC	N01AX13
UNII	K50XQU1029
EPA CompTox	DTXSID8021066


Active Pharmaceutical Ingredients Bioactive chemicals	Exact Similarity SubStructure	Threshold (%) >= 70

Structure


InChI Key	GQPLMRYTRLFLPF-UHFFFAOYSA-N
Smiles	[N-]=[N+]=O
InChI	InChI=1S/N2O/c1-2-3

Physicochemical Descriptors

Property Name	Value
Molecular Formula	N2O
Molecular Weight	44.01
AlogP	0.34
Hydrogen Bond Acceptor	2.0
Hydrogen Bond Donor	0.0
Number of Rotational Bond	0.0
Polar Surface Area	51.21
Molecular species	ACID
Aromatic Rings	0.0
Heavy Atoms	3.0

Cross References

Resources	Reference
ChEBI	17045
ChEMBL	CHEMBL1234579
DrugBank	DB06690
DrugCentral	4238
FDA SRS	K50XQU1029
Human Metabolome Database	HMDB0035807
KEGG	C00887
PDB	N2O
PubChem	948
SureChEMBL	SCHEMBL23060

CONTENTS


PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains. Elements of the website have been developed under projects PREMIER and the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains.

Elements of the website have been developed under projects PREMIER and the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).