EcoDrugPlus


Trade Names	ARIDOL ARIDOL KIT MANNITOL 10% MANNITOL 10% IN PLASTIC CONTAINER MANNITOL 10% W/ DEXTROSE 5% IN DISTILLED WATER MANNITOL 15% MANNITOL 15% IN PLASTIC CONTAINER MANNITOL 15% W/ DEXTROSE 5% IN SODIUM CHLORIDE 0.45% MANNITOL 20% MANNITOL 20% IN PLASTIC CONTAINER MANNITOL 25% MANNITOL 5% MANNITOL 5% IN PLASTIC CONTAINER MANNITOL 5% W/ DEXTROSE 5% IN SODIUM CHLORIDE 0.12% OSMITROL 10% IN WATER OSMITROL 10% IN WATER IN PLASTIC CONTAINER OSMITROL 15% IN WATER OSMITROL 15% IN WATER IN PLASTIC CONTAINER OSMITROL 20% IN WATER OSMITROL 20% IN WATER IN PLASTIC CONTAINER OSMITROL 5% IN WATER OSMITROL 5% IN WATER IN PLASTIC CONTAINER RESECTISOL RESECTISOL IN PLASTIC CONTAINER
Synonyms	Alexitol sodium Aridol kit Bronchitol Cordycepic acid Crystalline mannitol extra-fine Crystalline mannitol fine Crystalline mannitol standard D-(-)-mannitol D-mannitol Diosmol E-421 E421 INS NO.421 INS-421 Isomalt impurity, mannitol-
Status
Molecule Category	Free-form
ATC	A06AD16 B05BC01 B05CX04 R05CB16 V04CX04
UNII	3OWL53L36A
EPA CompTox	DTXSID30858955


InChI Key	FBPFZTCFMRRESA-KVTDHHQDSA-N
Smiles	OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
InChI	InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1

Property Name	Value
Molecular Formula	C6H14O6
Molecular Weight	182.17
AlogP	-3.59
Hydrogen Bond Acceptor	6.0
Hydrogen Bond Donor	6.0
Number of Rotational Bond	5.0
Polar Surface Area	121.38
Molecular species	NEUTRAL
Aromatic Rings	0.0
Heavy Atoms	12.0

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Enzyme Protease Serine protease Serine protease PA clan Serine protease S1A subfamily	-	-	-	-	29
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC22 family of organic cation and anion transporters	-	-	-	-

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Escherichia coli	-	-	-	-	0.6
Homo sapiens	-	-	-	-

Resources	Reference
ChEBI	16899
ChEMBL	CHEMBL689
DrugBank	DB00742
DrugCentral	935
FDA SRS	3OWL53L36A
Human Metabolome Database	HMDB0000765
KEGG	C00392
PDB	MTL
PubChem	6251
SureChEMBL	SCHEMBL919
ZINC	ZINC000002041302

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

MANNITOL

Structure

Physicochemical Descriptors

Pharmacology

Related Entries

Cross References