None is not found in the database.

MALATHION


Trade Names	MALATHION OVIDE
Synonyms	8059HC Cythion Derbac-m ENT 17,034 ENT-17034 Malathion NSC-6524 OVIDE Organoderm Ovide Prioderm Quellada-m Suleo-m
Status
Molecule Category	Free-form
ATC	P03AX03
UNII	U5N7SU872W
EPA CompTox	DTXSID4020791

Structure


InChI Key	JXSJBGJIGXNWCI-UHFFFAOYSA-N
Smiles	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC
InChI	InChI=1S/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C10H19O6PS2
Molecular Weight	330.36
AlogP	2.12
Hydrogen Bond Acceptor	8.0
Number of Rotational Bond	9.0
Polar Surface Area	71.06
Molecular species	NEUTRAL
Aromatic Rings	0.0
Heavy Atoms	19.0

Pharmacology

Mechanism of Action	Action	Reference
Acetylcholinesterase inhibitor	INHIBITOR	Wikipedia Wikipedia FDA

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Bionectria ochroleuca	-	-	-	-	10-14.9

Cross References

Resources	Reference
ChEBI	141474
ChEMBL	CHEMBL1200468
DrugBank	DB00772
DrugCentral	1626
FDA SRS	U5N7SU872W
Human Metabolome Database	HMDB0014910
KEGG	C07497
PharmGKB	PA164748092
PubChem	4004
SureChEMBL	SCHEMBL27358
ZINC	ZINC01530800

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025