LEVOBETAXOLOL HYDROCHLORIDE

/static/temp/default.svg

Search structure


Trade Names	BETAXON
Synonyms	AL-1577A AL1577A Betaxon Levobetaxolol hcl Levobetaxolol hydrochloride
Status
Molecule Category	Salt-form
UNII	8MR4W4O06J
EPA CompTox	DTXSID20151321

Structure


InChI Key	CHDPSNLJFOQTRK-LMOVPXPDSA-N
Smiles	CC(C)NC[C@H](O)COc1ccc(CCOCC2CC2)cc1.Cl
InChI	InChI=1S/C18H29NO3.ClH/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16;/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3;1H/t17-;/m0./s1

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C18H30ClNO3
Molecular Weight	343.9
AlogP	2.39
Hydrogen Bond Acceptor	4.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	11.0
Polar Surface Area	50.72
Molecular species	BASE
Aromatic Rings	1.0
Heavy Atoms	22.0

Pharmacology

Mechanism of Action	Action	Reference
Beta-1 adrenergic receptor antagonist	ANTAGONIST	PubMed

Target Conservation


Protein: Beta-1 adrenergic receptor Description: Beta-1 adrenergic receptor Organism : Homo sapiens P08588 ENSG00000043591

Cross References

Resources	Reference
ChEBI	59256
ChEMBL	CHEMBL1200837
FDA SRS	8MR4W4O06J
PubChem	60656
SureChEMBL	SCHEMBL42795

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025