ISOSORBIDE MONONITRATE

/static/temp/default.svg Search structure
Trade Names
Synonyms
Status
Molecule Category Free-form
ATC C01DA14
UNII LX1OH63030
EPA CompTox DTXSID9023176
Parent Compound: ISOSORBIDE

Structure

InChI Key YWXYYJSYQOXTPL-SLPGGIOYSA-N
Smiles O=[N+]([O-])O[C@@H]1CO[C@H]2[C@@H]1OC[C@@H]2O
InChI
InChI=1S/C6H9NO6/c8-3-1-11-6-4(13-7(9)10)2-12-5(3)6/h3-6,8H,1-2H2/t3-,4+,5+,6+/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C6H9NO6
Molecular Weight 191.14
AlogP -1.28
Hydrogen Bond Acceptor 6.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 2.0
Polar Surface Area 91.06
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 13.0

Pharmacology

Mechanism of Action Action Reference
Soluble guanylate cyclase activator ACTIVATOR FDA ISBN

Target Conservation

Protein: Soluble guanylate cyclase
Description: Guanylate cyclase soluble subunit alpha-2
Organism : Homo sapiens
P33402 ENSG00000152402
Protein: Soluble guanylate cyclase
Description: Guanylate cyclase soluble subunit alpha-1
Organism : Homo sapiens
Q02108 ENSG00000164116
Protein: Soluble guanylate cyclase
Description: Guanylate cyclase soluble subunit beta-1
Organism : Homo sapiens
Q02153 ENSG00000061918

Cross References

Resources Reference
ChEBI 6062
ChEMBL CHEMBL1311
DrugBank DB01020
DrugCentral 1506
FDA SRS LX1OH63030
Human Metabolome Database HMDB0015155
Guide to Pharmacology 7052
KEGG C07714
PharmGKB PA450126
PubChem 27661
SureChEMBL SCHEMBL26781
ZINC ZINC000001849548
CONTENTS