HALOTHANE

/static/temp/default.svg Search structure
Trade Names
Synonyms
Status
Molecule Category Free-form
ATC N01AB01
UNII UQT9G45D1P
EPA CompTox DTXSID4025371

Structure

InChI Key BCQZXOMGPXTTIC-UHFFFAOYSA-N
Smiles FC(F)(F)C(Cl)Br
InChI
InChI=1S/C2HBrClF3/c3-1(4)2(5,6)7/h1H

Physicochemical Descriptors

Property Name Value
Molecular Formula C2HBrClF3
Molecular Weight 197.38
AlogP 2.51
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 7.0

Pharmacology

Mechanism of Action Action Reference
GABA-A receptor; anion channel positive allosteric modulator POSITIVE ALLOSTERIC MODULATOR PubMed PubMed PubMed

Target Conservation

Protein: GABA-A receptor; anion channel
Description: Gamma-aminobutyric acid receptor subunit pi
Organism : Homo sapiens
O00591 ENSG00000094755
Protein: Potassium channel subfamily K member 3
Description: Potassium channel subfamily K member 3
Organism : Homo sapiens
O14649 ENSG00000171303
Protein: GABA-A receptor; anion channel
Description: Gamma-aminobutyric acid receptor subunit delta
Organism : Homo sapiens
O14764 ENSG00000187730
Protein: Potassium channel subfamily K member 2
Description: Potassium channel subfamily K member 2
Organism : Homo sapiens
O95069 ENSG00000082482
Protein: GABA-A receptor; anion channel
Description: Gamma-aminobutyric acid receptor subunit alpha-1
Organism : Homo sapiens
P14867 ENSG00000022355
Protein: GABA-A receptor; anion channel
Description: Gamma-aminobutyric acid receptor subunit beta-1
Organism : Homo sapiens
P18505 ENSG00000163288
Protein: GABA-A receptor; anion channel
Description: Gamma-aminobutyric acid receptor subunit gamma-2
Organism : Homo sapiens
P18507 ENSG00000113327
Protein: GABA-A receptor; anion channel
Description: Gamma-aminobutyric acid receptor subunit beta-3
Organism : Homo sapiens
P28472 ENSG00000166206
Protein: GABA-A receptor; anion channel
Description: Gamma-aminobutyric acid receptor subunit alpha-5
Organism : Homo sapiens
P31644 ENSG00000186297
Protein: GABA-A receptor; anion channel
Description: Gamma-aminobutyric acid receptor subunit alpha-3
Organism : Homo sapiens
P34903 ENSG00000011677
Protein: GABA-A receptor; anion channel
Description: Gamma-aminobutyric acid receptor subunit alpha-2
Organism : Homo sapiens
P47869 ENSG00000151834
Protein: GABA-A receptor; anion channel
Description: Gamma-aminobutyric acid receptor subunit beta-2
Organism : Homo sapiens
P47870 ENSG00000145864
Protein: GABA-A receptor; anion channel
Description: Gamma-aminobutyric acid receptor subunit alpha-4
Organism : Homo sapiens
P48169 ENSG00000109158
Protein: GABA-A receptor; anion channel
Description: Gamma-aminobutyric acid receptor subunit epsilon
Organism : Homo sapiens
P78334 ENSG00000102287
Protein: GABA-A receptor; anion channel
Description: Gamma-aminobutyric acid receptor subunit alpha-6
Organism : Homo sapiens
Q16445 ENSG00000145863
Protein: GABA-A receptor; anion channel
Description: Gamma-aminobutyric acid receptor subunit gamma-1
Organism : Homo sapiens
Q8N1C3 ENSG00000163285
Protein: GABA-A receptor; anion channel
Description: Gamma-aminobutyric acid receptor subunit gamma-3
Organism : Homo sapiens
Q99928 ENSG00000182256
Protein: Potassium channel subfamily K member 9
Description: Potassium channel subfamily K member 9
Organism : Homo sapiens
Q9NPC2 ENSG00000169427
Protein: GABA-A receptor; anion channel
Description: Gamma-aminobutyric acid receptor subunit theta
Organism : Homo sapiens
Q9UN88 ENSG00000268089

Cross References

Resources Reference
CAS NUMBER 151-67-7
ChEBI 5615
ChEMBL CHEMBL931
DrugBank DB01159
DrugCentral 1356
FDA SRS UQT9G45D1P
Human Metabolome Database HMDB0015290
Guide to Pharmacology 2401
KEGG C07515
PharmGKB PA449845
PubChem 3562
SureChEMBL SCHEMBL25588
ZINC ZINC08220828
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