EcoDrugPlus


Trade Names	RAXAR
Synonyms	Grepafloxacin hcl Grepafloxacin hydrochloride OPC-17116 Raxar
Status
Molecule Category	Salt-form
UNII	A4ER1Z8N9N
EPA CompTox	DTXSID0046692

Trade Names

RAXAR

Synonyms

Grepafloxacin hcl

Grepafloxacin hydrochloride

OPC-17116

Raxar

Status

Molecule Category

Salt-form

UNII

A4ER1Z8N9N

EPA CompTox

DTXSID0046692


InChI Key	IEPMBYOIQGCVHO-UHFFFAOYSA-N
Smiles	Cc1c(F)c(N2CCNC(C)C2)cc2c1c(=O)c(C(=O)O)cn2C1CC1.Cl
InChI	InChI=1S/C19H22FN3O3.ClH/c1-10-8-22(6-5-21-10)15-7-14-16(11(2)17(15)20)18(24)13(19(25)26)9-23(14)12-3-4-12;/h7,9-10,12,21H,3-6,8H2,1-2H3,(H,25,26);1H

InChI Key

IEPMBYOIQGCVHO-UHFFFAOYSA-N

Smiles

Cc1c(F)c(N2CCNC(C)C2)cc2c1c(=O)c(C(=O)O)cn2C1CC1.Cl

InChI

InChI=1S/C19H22FN3O3.ClH/c1-10-8-22(6-5-21-10)15-7-14-16(11(2)17(15)20)18(24)13(19(25)26)9-23(14)12-3-4-12;/h7,9-10,12,21H,3-6,8H2,1-2H3,(H,25,26);1H

Property Name	Value
Molecular Formula	C19H23ClFN3O3
Molecular Weight	395.86
AlogP	2.28
Hydrogen Bond Acceptor	5.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	3.0
Polar Surface Area	74.57
Molecular species	ZWITTERION
Aromatic Rings	2.0
Heavy Atoms	26.0

Property Name

Value

Molecular Formula

C19H23ClFN3O3

Molecular Weight

395.86

AlogP

2.28

Hydrogen Bond Acceptor

5.0

Hydrogen Bond Donor

2.0

Number of Rotational Bond

3.0

Polar Surface Area

74.57

Molecular species

ZWITTERION

Aromatic Rings

2.0

Heavy Atoms

26.0

Mechanism of Action	Action	Reference
DNA gyrase inhibitor	INHIBITOR	PubMed PubMed PubMed

Mechanism of Action

Action

Reference

DNA gyrase inhibitor

INHIBITOR

PubMed PubMed PubMed

Resources	Reference
ChEMBL	CHEMBL1200393
FDA SRS	A4ER1Z8N9N
KEGG	C11368
PubChem	656829
SureChEMBL	SCHEMBL137804
ZINC	ZINC00967787

Resources

Reference

ChEMBL

FDA SRS

KEGG

PubChem

SureChEMBL

ZINC

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025

GREPAFLOXACIN HYDROCHLORIDE

Structure

Physicochemical Descriptors

Pharmacology

Cross References