GRANISETRON HYDROCHLORIDE

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Trade Names
Synonyms
Status
Molecule Category Salt-form
UNII 318F6L70J8
Parent Compound: GRANISETRON

Structure

InChI Key QYZRTBKYBJRGJB-UHFFFAOYSA-N
Smiles CN1C2CCCC1CC(NC(=O)c1nn(C)c3ccccc13)C2.Cl
InChI
InChI=1S/C18H24N4O.ClH/c1-21-13-6-5-7-14(21)11-12(10-13)19-18(23)17-15-8-3-4-9-16(15)22(2)20-17;/h3-4,8-9,12-14H,5-7,10-11H2,1-2H3,(H,19,23);1H

Physicochemical Descriptors

Property Name Value
Molecular Formula C18H25ClN4O
Molecular Weight 348.88
AlogP 2.32
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 2.0
Polar Surface Area 50.16
Molecular species BASE
Aromatic Rings 2.0
Heavy Atoms 23.0

Pharmacology

Mechanism of Action Action Reference
Serotonin 3a (5-HT3a) receptor antagonist ANTAGONIST DailyMed

Target Conservation

Protein: Serotonin 3a (5-HT3a) receptor
Description: 5-hydroxytryptamine receptor 3A
Organism : Homo sapiens
P46098 ENSG00000166736

Cross References

Resources Reference
ChEMBL CHEMBL1237080
FDA SRS 318F6L70J8
PubChem 6918003
SureChEMBL SCHEMBL33433
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