EcoDrugPlus


Trade Names	GLYCEROL PHENYLBUTYRATE RAVICTI
Synonyms	Glycerol phenylbutyrate HPN-100 HPN100 Ravicti
Status
Molecule Category	Free-form
ATC	A16AX09
UNII	ZH6F1VCV7B
EPA CompTox	DTXSID40210005
Parent Compound:

Trade Names

GLYCEROL PHENYLBUTYRATE

RAVICTI

Synonyms

Glycerol phenylbutyrate

HPN-100

HPN100

Ravicti

Status

Molecule Category

Free-form

ATC

A16AX09

UNII

ZH6F1VCV7B

EPA CompTox

DTXSID40210005

Parent Compound:


InChI Key	ZSDBFLMJVAGKOU-UHFFFAOYSA-N
Smiles	O=C(CCCc1ccccc1)OCC(COC(=O)CCCc1ccccc1)OC(=O)CCCc1ccccc1
InChI	InChI=1S/C33H38O6/c34-31(22-10-19-27-13-4-1-5-14-27)37-25-30(39-33(36)24-12-21-29-17-8-3-9-18-29)26-38-32(35)23-11-20-28-15-6-2-7-16-28/h1-9,13-18,30H,10-12,19-26H2

InChI Key

ZSDBFLMJVAGKOU-UHFFFAOYSA-N

Smiles

O=C(CCCc1ccccc1)OCC(COC(=O)CCCc1ccccc1)OC(=O)CCCc1ccccc1

InChI

InChI=1S/C33H38O6/c34-31(22-10-19-27-13-4-1-5-14-27)37-25-30(39-33(36)24-12-21-29-17-8-3-9-18-29)26-38-32(35)23-11-20-28-15-6-2-7-16-28/h1-9,13-18,30H,10-12,19-26H2

Property Name	Value
Molecular Formula	C33H38O6
Molecular Weight	530.66
AlogP	6.05
Hydrogen Bond Acceptor	6.0
Number of Rotational Bond	17.0
Polar Surface Area	78.9
Heavy Atoms	39.0

Property Name

Value

Molecular Formula

C33H38O6

Molecular Weight

530.66

AlogP

6.05

Hydrogen Bond Acceptor

6.0

Number of Rotational Bond

17.0

Polar Surface Area

78.9

Heavy Atoms

39.0

Mechanism of Action	Action	Reference
Glutamine sequestering agent	SEQUESTERING AGENT	DailyMed

Mechanism of Action

Action

Reference

Glutamine sequestering agent

SEQUESTERING AGENT

DailyMed

Resources	Reference
ChEBI	134745
ChEMBL	CHEMBL2105745
DrugBank	DB08909
DrugCentral	4745
FDA SRS	ZH6F1VCV7B
PubChem	10482134
SureChEMBL	SCHEMBL10102804

Resources

Reference

ChEBI

ChEMBL

DrugBank

DrugCentral

FDA SRS

PubChem

SureChEMBL

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025

GLYCEROL PHENYLBUTYRATE

Structure

Physicochemical Descriptors

Pharmacology

Cross References