Trade Names | |
Synonyms | |
Status | |
Molecule Category | Free-form |
ATC | A10BB12 |
UNII | 6KY687524K |
EPA CompTox | DTXSID5040675 |
InChI Key | WIGIZIANZCJQQY-RUCARUNLSA-N |
---|---|
Smiles | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C24H34N4O5S |
Molecular Weight | 490.63 |
AlogP | 3.07 |
Hydrogen Bond Acceptor | 5.0 |
Hydrogen Bond Donor | 3.0 |
Number of Rotational Bond | 7.0 |
Polar Surface Area | 124.68 |
Molecular species | ACID |
Aromatic Rings | 1.0 |
Heavy Atoms | 34.0 |
Mechanism of Action | Action | Reference |
---|---|---|
Sulfonylurea receptor 1, Kir6.2 blocker | BLOCKER | PubMed PubMed PubMed DailyMed |
Protein: Sulfonylurea receptor 1, Kir6.2 Description: ATP-binding cassette sub-family C member 8 Organism : Homo sapiens Q09428 ENSG00000006071 |
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Protein: Sulfonylurea receptor 1, Kir6.2 Description: ATP-sensitive inward rectifier potassium channel 11 Organism : Homo sapiens Q14654 ENSG00000187486 |
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Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Enzyme
Oxidoreductase
|
- | 6860 | - | - | - | |
Enzyme
|
- | 6860 | - | - | - | |
Transporter
Primary active transporter
ATP-binding cassette
ABCB subfamily
|
- | 15700-34000 | - | - | - | |
Transporter
Primary active transporter
ATP-binding cassette
ABCC subfamily
|
- | 6390 | - | - | - |
Resources | Reference |
---|---|
ChEBI | 5383 |
ChEMBL | CHEMBL1481 |
DrugBank | DB00222 |
DrugCentral | 1300 |
FDA SRS | 6KY687524K |
Guide to Pharmacology | 6820 |
SureChEMBL | SCHEMBL16086 |
ZINC | ZINC000100070954 |