FROVATRIPTAN SUCCINATE

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Trade Names
Synonyms
Status
Molecule Category Salt-form
UNII D28J6W18HY
EPA CompTox DTXSID2049056
Parent Compound: FROVATRIPTAN

Structure

InChI Key CUETXFMONOSVJA-KLQYNRQASA-N
Smiles CN[C@@H]1CCc2[nH]c3ccc(C(N)=O)cc3c2C1.O.O=C(O)CCC(=O)O
InChI
InChI=1S/C14H17N3O.C4H6O4.H2O/c1-16-9-3-5-13-11(7-9)10-6-8(14(15)18)2-4-12(10)17-13;5-3(6)1-2-4(7)8;/h2,4,6,9,16-17H,3,5,7H2,1H3,(H2,15,18);1-2H2,(H,5,6)(H,7,8);1H2/t9-;;/m1../s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C18H25N3O6
Molecular Weight 379.41
AlogP 1.34
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 2.0
Polar Surface Area 70.91
Molecular species BASE
Aromatic Rings 2.0
Heavy Atoms 18.0

Pharmacology

Mechanism of Action Action Reference
Serotonin 1b (5-HT1b) receptor agonist AGONIST FDA

Target Conservation

Protein: Serotonin 1d (5-HT1d) receptor
Description: 5-hydroxytryptamine receptor 1D
Organism : Homo sapiens
P28221 ENSG00000179546
Protein: Serotonin 1b (5-HT1b) receptor
Description: 5-hydroxytryptamine receptor 1B
Organism : Homo sapiens
P28222 ENSG00000135312

Cross References

Resources Reference
ChEMBL CHEMBL2138684
FDA SRS D28J6W18HY
Guide to Pharmacology 7191
KEGG D07997
PubChem 152943
SureChEMBL SCHEMBL2321442
ZINC ZINC00018635
CONTENTS