DROSPIRENONE

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Trade Names
Synonyms
Status
Molecule Category Free-form
ATC G03AC10
UNII N295J34A25
EPA CompTox DTXSID7046465

Structure

InChI Key METQSPRSQINEEU-HXCATZOESA-N
Smiles C[C@]12CCC(=O)C=C1[C@@H]1C[C@@H]1[C@H]1[C@@H]3[C@@H]4C[C@@H]4[C@@]4(CCC(=O)O4)[C@@]3(C)CC[C@@H]12
InChI
InChI=1S/C24H30O3/c1-22-6-3-12(25)9-17(22)13-10-14(13)20-16(22)4-7-23(2)21(20)15-11-18(15)24(23)8-5-19(26)27-24/h9,13-16,18,20-21H,3-8,10-11H2,1-2H3/t13-,14+,15-,16+,18+,20-,21+,22-,23+,24+/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C24H30O3
Molecular Weight 366.5
AlogP 4.31
Hydrogen Bond Acceptor 3.0
Polar Surface Area 43.37
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 27.0

Pharmacology

Mechanism of Action Action Reference
Mineralocorticoid receptor antagonist ANTAGONIST PubMed DailyMed

Target Conservation

Protein: Progesterone receptor
Description: Progesterone receptor
Organism : Homo sapiens
P06401 ENSG00000082175
Protein: Mineralocorticoid receptor
Description: Mineralocorticoid receptor
Organism : Homo sapiens
P08235 ENSG00000151623

Related Entries

Cross References

Resources Reference
ChEBI 50838
ChEMBL CHEMBL1509
DrugBank DB01395
DrugCentral 968
FDA SRS N295J34A25
Human Metabolome Database HMDB0015467
Guide to Pharmacology 2874
PharmGKB PA164749409
PubChem 68873
SureChEMBL SCHEMBL153316
ZINC ZINC000003927200
CONTENTS