EcoDrugPlus


Trade Names	AKPRO DIPIVEFRIN HYDROCHLORIDE PROPINE
Synonyms	Akpro Dipivefrin hcl Dipivefrin hydrochloride Dipivefrine hydrochloride Propine
Status
Molecule Category	Salt-form
UNII	5QTH9UHV0K
EPA CompTox	DTXSID2045494

Trade Names

AKPRO

DIPIVEFRIN HYDROCHLORIDE

PROPINE

Synonyms

Akpro

Dipivefrin hcl

Dipivefrin hydrochloride

Dipivefrine hydrochloride

Propine

Status

Molecule Category

Salt-form

UNII

5QTH9UHV0K

EPA CompTox

DTXSID2045494


InChI Key	VKFAUCPBMAGVRG-UHFFFAOYSA-N
Smiles	CNCC(O)c1ccc(OC(=O)C(C)(C)C)c(OC(=O)C(C)(C)C)c1.Cl
InChI	InChI=1S/C19H29NO5.ClH/c1-18(2,3)16(22)24-14-9-8-12(13(21)11-20-7)10-15(14)25-17(23)19(4,5)6;/h8-10,13,20-21H,11H2,1-7H3;1H

InChI Key

VKFAUCPBMAGVRG-UHFFFAOYSA-N

Smiles

CNCC(O)c1ccc(OC(=O)C(C)(C)C)c(OC(=O)C(C)(C)C)c1.Cl

InChI

InChI=1S/C19H29NO5.ClH/c1-18(2,3)16(22)24-14-9-8-12(13(21)11-20-7)10-15(14)25-17(23)19(4,5)6;/h8-10,13,20-21H,11H2,1-7H3;1H

Property Name	Value
Molecular Formula	C19H30ClNO5
Molecular Weight	387.9
AlogP	2.84
Hydrogen Bond Acceptor	6.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	5.0
Polar Surface Area	84.86
Molecular species	BASE
Aromatic Rings	1.0
Heavy Atoms	25.0

Property Name

Value

Molecular Formula

C19H30ClNO5

Molecular Weight

387.9

AlogP

2.84

Hydrogen Bond Acceptor

6.0

Hydrogen Bond Donor

2.0

Number of Rotational Bond

5.0

Polar Surface Area

84.86

Molecular species

BASE

Aromatic Rings

1.0

Heavy Atoms

25.0

Mechanism of Action	Action	Reference
Adrenergic receptor agonist	AGONIST	FDA

Mechanism of Action

Action

Reference

Adrenergic receptor agonist

AGONIST

FDA

Resources	Reference
ChEBI	4647
ChEMBL	CHEMBL1200833
FDA SRS	5QTH9UHV0K
PubChem	71486
SureChEMBL	SCHEMBL41350

Resources

Reference

ChEBI

ChEMBL

FDA SRS

PubChem

SureChEMBL

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025

DIPIVEFRIN HYDROCHLORIDE

Structure

Physicochemical Descriptors

Pharmacology

Cross References