EcoDrugPlus


Trade Names	DEFERIPRONE FERRIPROX
Synonyms	APO-066 APO-66 CP-20 CP20 DN-180-01-AF DN-18001AF Deferipron Deferiprone Ferriprox L-1 L1 NSC-758880 PL-1 PL1
Status
Molecule Category	Free-form
ATC	V03AC02
UNII	2BTY8KH53L
EPA CompTox	DTXSID6040666

Trade Names

DEFERIPRONE

FERRIPROX

Synonyms

APO-066

APO-66

CP-20

CP20

DN-180-01-AF

DN-18001AF

Deferipron

Deferiprone

Ferriprox

L-1

NSC-758880

PL-1

PL1

Status

Molecule Category

Free-form

ATC

V03AC02

UNII

2BTY8KH53L

EPA CompTox

DTXSID6040666


InChI Key	TZXKOCQBRNJULO-UHFFFAOYSA-N
Smiles	Cc1c(O)c(=O)ccn1C
InChI	InChI=1S/C7H9NO2/c1-5-7(10)6(9)3-4-8(5)2/h3-4,10H,1-2H3

InChI Key

TZXKOCQBRNJULO-UHFFFAOYSA-N

Smiles

Cc1c(O)c(=O)ccn1C

InChI

InChI=1S/C7H9NO2/c1-5-7(10)6(9)3-4-8(5)2/h3-4,10H,1-2H3

Property Name	Value
Molecular Formula	C7H9NO2
Molecular Weight	139.15
AlogP	0.4
Hydrogen Bond Acceptor	3.0
Hydrogen Bond Donor	1.0
Polar Surface Area	42.23
Molecular species	NEUTRAL
Aromatic Rings	1.0
Heavy Atoms	10.0

Property Name

Value

Molecular Formula

C7H9NO2

Molecular Weight

139.15

AlogP

0.4

Hydrogen Bond Acceptor

3.0

Hydrogen Bond Donor

1.0

Polar Surface Area

42.23

Molecular species

NEUTRAL

Aromatic Rings

1.0

Heavy Atoms

10.0

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Glycine max	-	-	-	-	58
Mus musculus	-	200	-	-	-

EC50(nM)

IC50(nM)

Kd(nM)

Ki(nM)

Inhibition(%)

Glycine max

Mus musculus

200

Resources	Reference
ChEBI	68554
ChEMBL	CHEMBL70927
DrugBank	DB08826
DrugCentral	4188
FDA SRS	2BTY8KH53L
Guide to Pharmacology	7456
PharmGKB	PA166118041
PubChem	2972
SureChEMBL	SCHEMBL94474
ZINC	ZINC000000006226

Resources

Reference

ChEBI

ChEMBL

DrugBank

DrugCentral

FDA SRS

Guide to Pharmacology

PharmGKB

PubChem

SureChEMBL

ZINC

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

DEFERIPRONE

Structure

Physicochemical Descriptors

Pharmacology

Cross References