None is not found in the database.

CROFELEMER

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Search structure


Trade Names	MYTESI
Synonyms	Crofelemer Fulyzaq Mytesi NP-303 Provir SP-303 TRN-002 Virend
Status
Molecule Category	Free-form
ATC	A07XA06
UNII	PY79D6C8RX

Pharmacology

Mechanism of Action	Action	Reference
Anoctamin-1 blocker	BLOCKER	DailyMed PubMed

Target Conservation


Protein: Cystic fibrosis transmembrane conductance regulator Description: Cystic fibrosis transmembrane conductance regulator Organism : Homo sapiens P13569 ENSG00000001626

Cross References

Resources	Reference
ChEMBL	CHEMBL2108184
FDA SRS	PY79D6C8RX
Guide to Pharmacology	7453

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025