CICLESONIDE

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Trade Names
Synonyms
Status
Molecule Category Free-form
ATC R01AD13 R03BA08
UNII S59502J185
EPA CompTox DTXSID9046659

Structure

InChI Key LUKZNWIVRBCLON-GXOBDPJESA-N
Smiles CC(C)C(=O)OCC(=O)[C@@]12O[C@H](C3CCCCC3)O[C@@H]1C[C@H]1[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]12C
InChI
InChI=1S/C32H44O7/c1-18(2)28(36)37-17-25(35)32-26(38-29(39-32)19-8-6-5-7-9-19)15-23-22-11-10-20-14-21(33)12-13-30(20,3)27(22)24(34)16-31(23,32)4/h12-14,18-19,22-24,26-27,29,34H,5-11,15-17H2,1-4H3/t22-,23-,24-,26+,27+,29+,30-,31-,32+/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C32H44O7
Molecular Weight 540.7
AlogP 4.7
Hydrogen Bond Acceptor 7.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 5.0
Polar Surface Area 99.13
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 39.0

Pharmacology

Mechanism of Action Action Reference
Glucocorticoid receptor agonist AGONIST PubMed DailyMed

Target Conservation

Protein: Glucocorticoid receptor
Description: Glucocorticoid receptor
Organism : Homo sapiens
P04150 ENSG00000113580

Related Entries

Cross References

Resources Reference
ChEBI 31397
ChEMBL CHEMBL2040682
DrugBank DB01410
DrugCentral 633
FDA SRS S59502J185
Guide to Pharmacology 7469
PubChem 6918155
SureChEMBL SCHEMBL3688
ZINC ZINC000003915154
CONTENTS