CHLORPHENTERMINE HYDROCHLORIDE

/static/temp/default.svg

Search structure


Trade Names	PRE-SATE
Synonyms	Chlorphentermine hcl Chlorphentermine hydrochloride NSC-76098 Pre-sate S-62 W 2426 W-2426
Status
Molecule Category	Salt-form
UNII	RL11HOJ7DM
EPA CompTox	DTXSID1047815

Structure


InChI Key	WEJDYJKJPUPMLH-UHFFFAOYSA-N
Smiles	CC(C)(N)Cc1ccc(Cl)cc1.Cl
InChI	InChI=1S/C10H14ClN.ClH/c1-10(2,12)7-8-3-5-9(11)6-4-8;/h3-6H,7,12H2,1-2H3;1H

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C10H15Cl2N
Molecular Weight	220.14
AlogP	2.62
Hydrogen Bond Acceptor	1.0
Hydrogen Bond Donor	1.0
Number of Rotational Bond	2.0
Polar Surface Area	26.02
Molecular species	BASE
Aromatic Rings	1.0
Heavy Atoms	12.0

Pharmacology

Mechanism of Action	Action	Reference
Serotonin transporter substrate	SUBSTRATE	PubMed PubMed

Target Conservation


Protein: Serotonin transporter Description: Sodium-dependent serotonin transporter Organism : Homo sapiens P31645 ENSG00000108576

Cross References

Resources	Reference
ChEMBL	CHEMBL1200595
FDA SRS	RL11HOJ7DM
KEGG	C07559
PubChem	65477
SureChEMBL	SCHEMBL124013
ZINC	ZINC00122765

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025