CHLOROTHIAZIDE SODIUM

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Trade Names
Synonyms
Status
Molecule Category Salt-form
UNII SN86FG7N2K
EPA CompTox DTXSID00221091
Parent Compound: CHLOROTHIAZIDE

Structure

InChI Key CPIWHAFLBZQYLQ-UHFFFAOYSA-N
Smiles NS(=O)(=O)c1cc2c(cc1Cl)N=C[N-]S2(=O)=O.[Na+]
InChI
InChI=1S/C7H5ClN3O4S2.Na/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5;/h1-3H,(H2-,9,10,11,12,13);/q-1;+1

Physicochemical Descriptors

Property Name Value
Molecular Formula C7H5ClN3NaO4S2
Molecular Weight 317.71
AlogP -0.06
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 1.0
Polar Surface Area 118.69
Molecular species ACID
Aromatic Rings 1.0
Heavy Atoms 17.0

Pharmacology

Mechanism of Action Action Reference
Thiazide-sensitive sodium-chloride cotransporter inhibitor INHIBITOR DOI

Cross References

Resources Reference
ChEMBL CHEMBL1200616
FDA SRS SN86FG7N2K
PubChem 23675744
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