EcoDrugPlus


Trade Names	CEFDINIR OMNICEF
Synonyms	BMY-28488 CI-983 Cefdinir Cefdinir anhydrous Cefzon FK 482 FK-482 NSC-758926 Omnicef
Status
Molecule Category	Free-form
ATC	J01DD15
UNII	CI0FAO63WC
EPA CompTox	DTXSID8046084


InChI Key	RTXOFQZKPXMALH-GHXIOONMSA-N
Smiles	C=CC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)/C(=N\O)c3csc(N)n3)[C@H]2SC1
InChI	InChI=1S/C14H13N5O5S2/c1-2-5-3-25-12-8(11(21)19(12)9(5)13(22)23)17-10(20)7(18-24)6-4-26-14(15)16-6/h2,4,8,12,24H,1,3H2,(H2,15,16)(H,17,20)(H,22,23)/b18-7-/t8-,12-/m1/s1

Property Name	Value
Molecular Formula	C14H13N5O5S2
Molecular Weight	395.42
AlogP	-0.17
Hydrogen Bond Acceptor	9.0
Hydrogen Bond Donor	4.0
Number of Rotational Bond	5.0
Polar Surface Area	158.21
Molecular species	ACID
Aromatic Rings	1.0
Heavy Atoms	26.0

Mechanism of Action	Action	Reference
Bacterial penicillin-binding protein inhibitor	INHIBITOR	PubMed PubMed DailyMed Wikipedia Wikipedia

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides	-	-	-	-	78.64-92.13

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Cricetulus griseus	-	-	-	-	78.64-92.13

Resources	Reference
ChEBI	3485
ChEMBL	CHEMBL927
DrugBank	DB00535
DrugCentral	533
FDA SRS	CI0FAO63WC
Human Metabolome Database	HMDB0014675
KEGG	C08110
PharmGKB	PA164768739
PubChem	6915944
SureChEMBL	SCHEMBL36995
ZINC	ZINC000003927198

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

CEFDINIR

Structure

Physicochemical Descriptors

Pharmacology

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