BROMODIPHENHYDRAMINE HYDROCHLORIDE

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Search structure


Trade Names	AMBODRYL
Synonyms	Ambodryl Bromazine Bromodiphenhydramine hcl Bromodiphenhydramine hydrochloride NSC-36113
Status
Molecule Category	Salt-form
UNII	202J683U97
EPA CompTox	DTXSID70904541

Structure


InChI Key	ZQDJSWUEGOYDGT-UHFFFAOYSA-N
Smiles	CN(C)CCOC(c1ccccc1)c1ccc(Br)cc1.Cl
InChI	InChI=1S/C17H20BrNO.ClH/c1-19(2)12-13-20-17(14-6-4-3-5-7-14)15-8-10-16(18)11-9-15;/h3-11,17H,12-13H2,1-2H3;1H

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C17H21BrClNO
Molecular Weight	370.72
AlogP	4.12
Hydrogen Bond Acceptor	2.0
Number of Rotational Bond	6.0
Polar Surface Area	12.47
Molecular species	BASE
Aromatic Rings	2.0
Heavy Atoms	20.0

Pharmacology

Mechanism of Action	Action	Reference
Histamine H1 receptor antagonist	ANTAGONIST	PubMed PubMed

Target Conservation


Protein: Histamine H1 receptor Description: Histamine H1 receptor Organism : Homo sapiens P35367 ENSG00000196639

Cross References

Resources	Reference
CAS NUMBER	1808-12-4
ChEBI	59178
ChEMBL	CHEMBL1200967
FDA SRS	202J683U97
PubChem	15736
SureChEMBL	SCHEMBL141831

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, Volume 54, Issue D1, 6 January 2026, Pages D1397–D1404, https://doi.org/10.1093/nar/gkaf1251

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Last update: Monday, 23^rd March 2026