EcoDrugPlus


Trade Names	BESIVANCE
Synonyms	BOL-303224-A Besifloxacin (as hydrochloride) Besifloxacin hcl Besifloxacin hydrochloride Besivance SS-734 SS734
Status
Molecule Category	Salt-form
UNII	7506A6J57T
EPA CompTox	DTXSID20193529
Parent Compound:	BESIFLOXACIN

Trade Names

BESIVANCE

Synonyms

BOL-303224-A

Besifloxacin (as hydrochloride)

Besifloxacin hcl

Besifloxacin hydrochloride

Besivance

SS-734

SS734

Status

Molecule Category

Salt-form

UNII

7506A6J57T

EPA CompTox

DTXSID20193529

Parent Compound:

BESIFLOXACIN


InChI Key	PMQBICKXAAKXAY-HNCPQSOCSA-N
Smiles	Cl.N[C@@H]1CCCCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2Cl)C1
InChI	InChI=1S/C19H21ClFN3O3.ClH/c20-15-16-12(18(25)13(19(26)27)9-24(16)11-4-5-11)7-14(21)17(15)23-6-2-1-3-10(22)8-23;/h7,9-11H,1-6,8,22H2,(H,26,27);1H/t10-;/m1./s1

InChI Key

PMQBICKXAAKXAY-HNCPQSOCSA-N

Smiles

Cl.N[C@@H]1CCCCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2Cl)C1

InChI

InChI=1S/C19H21ClFN3O3.ClH/c20-15-16-12(18(25)13(19(26)27)9-24(16)11-4-5-11)7-14(21)17(15)23-6-2-1-3-10(22)8-23;/h7,9-11H,1-6,8,22H2,(H,26,27);1H/t10-;/m1./s1

Property Name	Value
Molecular Formula	C19H22Cl2FN3O3
Molecular Weight	430.31
AlogP	3.14
Hydrogen Bond Acceptor	5.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	3.0
Polar Surface Area	88.56
Molecular species	ZWITTERION
Aromatic Rings	2.0
Heavy Atoms	27.0

Property Name

Value

Molecular Formula

C19H22Cl2FN3O3

Molecular Weight

430.31

AlogP

3.14

Hydrogen Bond Acceptor

5.0

Hydrogen Bond Donor

2.0

Number of Rotational Bond

3.0

Polar Surface Area

88.56

Molecular species

ZWITTERION

Aromatic Rings

2.0

Heavy Atoms

27.0

Mechanism of Action	Action	Reference
Bacterial DNA gyrase inhibitor	INHIBITOR	FDA

Mechanism of Action

Action

Reference

Bacterial DNA gyrase inhibitor

INHIBITOR

FDA

Resources	Reference
ChEMBL	CHEMBL1201761
FDA SRS	7506A6J57T
PubChem	10224595
SureChEMBL	SCHEMBL291598

Resources

Reference

ChEMBL

FDA SRS

PubChem

SureChEMBL

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025

BESIFLOXACIN HYDROCHLORIDE

Structure

Physicochemical Descriptors

Pharmacology

Cross References