EcoDrugPlus


Trade Names	RUZURGI
Synonyms	3,4-DAP 3,4-Diammoniopyridinium 4-DAP Amifampridine DAP Dynamine NSC-521760 Pyridine-3,4-Diamine Ruzurgi
Status
Molecule Category	Free-form
ATC	N07XX05
UNII	RU4S6E2G0J
EPA CompTox	DTXSID6046715

Trade Names

RUZURGI

Synonyms

3,4-DAP

3,4-Diammoniopyridinium

4-DAP

Amifampridine

DAP

Dynamine

NSC-521760

Pyridine-3,4-Diamine

Ruzurgi

Status

Molecule Category

Free-form

ATC

N07XX05

UNII

RU4S6E2G0J

EPA CompTox

DTXSID6046715


InChI Key	OYTKINVCDFNREN-UHFFFAOYSA-N
Smiles	Nc1ccncc1N
InChI	InChI=1S/C5H7N3/c6-4-1-2-8-3-5(4)7/h1-3H,7H2,(H2,6,8)

InChI Key

OYTKINVCDFNREN-UHFFFAOYSA-N

Smiles

Nc1ccncc1N

InChI

InChI=1S/C5H7N3/c6-4-1-2-8-3-5(4)7/h1-3H,7H2,(H2,6,8)

Property Name	Value
Molecular Formula	C5H7N3
Molecular Weight	109.13
AlogP	0.25
Hydrogen Bond Acceptor	3.0
Hydrogen Bond Donor	2.0
Polar Surface Area	64.93
Molecular species	BASE
Aromatic Rings	1.0
Heavy Atoms	8.0

Property Name

Value

Molecular Formula

C5H7N3

Molecular Weight

109.13

AlogP

0.25

Hydrogen Bond Acceptor

3.0

Hydrogen Bond Donor

2.0

Polar Surface Area

64.93

Molecular species

BASE

Aromatic Rings

1.0

Heavy Atoms

8.0

Mechanism of Action	Action	Reference
Voltage-gated potassium channel blocker	BLOCKER	FDA Other

Mechanism of Action

Action

Reference

Voltage-gated potassium channel blocker

BLOCKER

FDA Other

Resources	Reference
ChEBI	135948
ChEMBL	CHEMBL354077
DrugBank	DB11640
DrugCentral	4336
FDA SRS	RU4S6E2G0J
Guide to Pharmacology	8032
PDB	L89
PubChem	5918
SureChEMBL	SCHEMBL21273
ZINC	ZINC000000164000

Resources

Reference

ChEBI

ChEMBL

DrugBank

DrugCentral

FDA SRS

Guide to Pharmacology

PDB

PubChem

SureChEMBL

ZINC

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

AMIFAMPRIDINE

Structure

Physicochemical Descriptors

Pharmacology

Cross References