ALFENTANIL HYDROCHLORIDE

/static/temp/default.svg

Search structure


Trade Names	ALFENTA ALFENTANIL
Synonyms	Alfenta Alfentanil Alfentanil hydrochloride Alfentanil hydrochloride cii Alfentanil hydrochloride monohydrate R 39,209 R 39209 R-39,209 R-39209 Rapifen Rapifen conc Rapifen dilute Rapifen intensive care
Status
Molecule Category	Salt-form
UNII	333JTI7A2M
EPA CompTox	DTXSID0048927
Parent Compound:	ALFENTANIL

Structure


InChI Key	AQORHZJDCHLLJN-UHFFFAOYSA-N
Smiles	CCC(=O)N(c1ccccc1)C1(COC)CCN(CCn2nnn(CC)c2=O)CC1.Cl
InChI	InChI=1S/C21H32N6O3.ClH/c1-4-19(28)27(18-9-7-6-8-10-18)21(17-30-3)11-13-24(14-12-21)15-16-26-20(29)25(5-2)22-23-26;/h6-10H,4-5,11-17H2,1-3H3;1H

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C21H33ClN6O3
Molecular Weight	452.99
AlogP	1.38
Hydrogen Bond Acceptor	8.0
Number of Rotational Bond	9.0
Polar Surface Area	85.49
Molecular species	NEUTRAL
Aromatic Rings	2.0
Heavy Atoms	30.0

Pharmacology

Mechanism of Action	Action	Reference
Mu opioid receptor agonist	AGONIST	PubMed DailyMed

Target Conservation


Protein: Mu opioid receptor Description: Mu-type opioid receptor Organism : Homo sapiens P35372 ENSG00000112038

Cross References

Resources	Reference
ChEMBL	CHEMBL1200531
FDA SRS	333JTI7A2M
PubChem	64762
SureChEMBL	SCHEMBL40459

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025