ATROPINE SULFATE


Trade Names	ATROPINE SULFATE ATROPINE SULFATE ANSYR PLASTIC SYRINGE ATROPINE SULFATE LIFESHIELD ABBOJECT SYRINGE ISOPTO ATROPINE
Synonyms	Atropine Atropine sulfate Atropine sulfate anhydrous Atropine sulfate ansyr plastic syringe Atropine sulfate hydrate Atropine sulfate lifeshield abboject syringe Atropine sulfate monohydrate Atropine sulphate Atropini sulfas Atropinum sulphuricum Atropt Isopto atropine NSC-26671 NSC-755889
Status
Molecule Category	Salt-form
UNII	03J5ZE7KA5
Parent Compound:	ATROPINE


InChI Key	VJFQPODMEGSXHC-RIMUKSHESA-N
Smiles	CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2.O=S(=O)(O)O
InChI	InChI=1S/C17H23NO3.H2O4S/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12;1-5(2,3)4/h2-6,13-16,19H,7-11H2,1H3;(H2,1,2,3,4)/t13-,14+,15+,16?;

Mechanism of Action	Action	Reference
Muscarinic acetylcholine receptor M1 antagonist	ANTAGONIST	FDA ISBN Wikipedia

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Enzyme Hydrolase	-	-	-	-	4.01-15.2

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Cavia porcellus	-	-	0.49-602.56	-	100
Electrophorus electricus	-	-	-	-	15.2
Equus caballus	-	-	-	-	4.01
Mus musculus	-	-	-	-	27


Protein: Muscarinic acetylcholine receptor M2 Description: Muscarinic acetylcholine receptor M2 Organism : Homo sapiens P08172 ENSG00000181072










Protein: Muscarinic acetylcholine receptor M1 Description: Muscarinic acetylcholine receptor M1 Organism : Homo sapiens P11229 ENSG00000168539










Protein: Muscarinic acetylcholine receptor M3 Description: Muscarinic acetylcholine receptor M3 Organism : Homo sapiens P20309 ENSG00000133019

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