Gene: PSMB7
Ensembl ID : ENSG00000136930
Description: proteasome 20S subunit beta 7
Gene Synonyms: Z
6 APIs:
218 Possible Orthologues:

Degradation of GLI2 by the proteasome R-HSA-5610783
Disease R-HSA-1643685
Metabolism of RNA R-HSA-8953854
FCERI mediated NF-kB activation R-HSA-2871837
Neddylation R-HSA-8951664
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCF dependent signaling in response to WNT R-HSA-201681
p53-Dependent G1 DNA Damage Response R-HSA-69563
Nervous system development R-HSA-9675108
Programmed Cell Death R-HSA-5357801
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of expression of SLITs and ROBOs R-HSA-9010553
FCERI mediated NF-kB activation R-HSA-2871837
C-type lectin receptors (CLRs) R-HSA-5621481
RAF/MAP kinase cascade R-HSA-5673001
DNA Replication Pre-Initiation R-HSA-69002
Metabolism of RNA R-HSA-8953854
Antigen processing-Cross presentation R-HSA-1236975
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Interleukin-1 signaling R-HSA-9020702
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular response to chemical stress R-HSA-9711123
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
TCR signaling R-HSA-202403
Innate Immune System R-HSA-168249
Neddylation R-HSA-8951664
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by WNT R-HSA-195721
Mitotic G2-G2/M phases R-HSA-453274
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Negative regulation of NOTCH4 signaling R-HSA-9604323
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
PIP3 activates AKT signaling R-HSA-1257604
Ub-specific processing proteases R-HSA-5689880
HIV Infection R-HSA-162906
Orc1 removal from chromatin R-HSA-68949
Signaling by the B Cell Receptor (BCR) R-HSA-983705
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
PTEN Regulation R-HSA-6807070
Regulation of RAS by GAPs R-HSA-5658442
Gene expression (Transcription) R-HSA-74160
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S Transition R-HSA-69206
Transport of small molecules R-HSA-382551
Switching of origins to a post-replicative state R-HSA-69052
Regulation of mitotic cell cycle R-HSA-453276
Hh mutants abrogate ligand secretion R-HSA-5387390
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RNA Polymerase II Transcription R-HSA-73857
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cytokine Signaling in Immune system R-HSA-1280215
Cellular responses to stimuli R-HSA-8953897
Vpu mediated degradation of CD4 R-HSA-180534
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by Hedgehog R-HSA-5358351
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Synthesis of DNA R-HSA-69239
Apoptosis R-HSA-109581
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
Asymmetric localization of PCP proteins R-HSA-4608870
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of RUNX2 expression and activity R-HSA-8939902
Intracellular signaling by second messengers R-HSA-9006925
Infectious disease R-HSA-5663205
Post-translational protein modification R-HSA-597592
ABC-family proteins mediated transport R-HSA-382556
Axon guidance R-HSA-422475
Regulation of Apoptosis R-HSA-169911
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of PTEN stability and activity R-HSA-8948751
Host Interactions of HIV factors R-HSA-162909
G2/M Checkpoints R-HSA-69481
Degradation of DVL R-HSA-4641258
Hedgehog 'on' state R-HSA-5632684
PCP/CE pathway R-HSA-4086400
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Transition R-HSA-69275
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Independent DNA Damage Response R-HSA-69610
Transcriptional regulation by RUNX2 R-HSA-8878166
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
ER-Phagosome pathway R-HSA-1236974
Metabolism R-HSA-1430728
Cell Cycle R-HSA-1640170
Hedgehog ligand biogenesis R-HSA-5358346
Downstream TCR signaling R-HSA-202424
Neutrophil degranulation R-HSA-6798695
Mitotic G1 phase and G1/S transition R-HSA-453279
Developmental Biology R-HSA-1266738
MAPK1/MAPK3 signaling R-HSA-5684996
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK family signaling cascades R-HSA-5683057
Signaling by NOTCH4 R-HSA-9013694
Adaptive Immune System R-HSA-1280218
Assembly of the pre-replicative complex R-HSA-68867
Regulation of RUNX3 expression and activity R-HSA-8941858
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle, Mitotic R-HSA-69278
Beta-catenin independent WNT signaling R-HSA-3858494
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
M Phase R-HSA-68886
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of polyamines R-HSA-351202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by NOTCH R-HSA-157118
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation by RUNX3 R-HSA-8878159
Disorders of transmembrane transporters R-HSA-5619115
Mitotic Metaphase and Anaphase R-HSA-2555396
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of GLI2 by the proteasome R-HSA-5610783
Disease R-HSA-1643685
Signaling by ROBO receptors R-HSA-376176
Mitotic Anaphase R-HSA-68882
ABC transporter disorders R-HSA-5619084
Degradation of AXIN R-HSA-4641257
Defective CFTR causes cystic fibrosis R-HSA-5678895
Separation of Sister Chromatids R-HSA-2467813
DNA Replication R-HSA-69306
Cell Cycle Checkpoints R-HSA-69620
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 family signaling R-HSA-446652
Stabilization of p53 R-HSA-69541
Hedgehog 'off' state R-HSA-5610787
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Deubiquitination R-HSA-5688426
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
UCH proteinases R-HSA-5689603
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by Interleukins R-HSA-449147
Signaling by NOTCH4 R-HSA-9013694
Orc1 removal from chromatin R-HSA-68949
Degradation of DVL R-HSA-4641258
Cellular response to hypoxia R-HSA-1234174
Axon guidance R-HSA-422475
Ub-specific processing proteases R-HSA-5689880
Switching of origins to a post-replicative state R-HSA-69052
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
RNA Polymerase II Transcription R-HSA-73857
Developmental Biology R-HSA-1266738
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of polyamines R-HSA-351202
Downstream TCR signaling R-HSA-202424
Metabolism of RNA R-HSA-8953854
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Class I MHC mediated antigen processing & presentation R-HSA-983169
Neutrophil degranulation R-HSA-6798695
Synthesis of DNA R-HSA-69239
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of amino acids and derivatives R-HSA-71291
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Gene expression (Transcription) R-HSA-74160
G2/M Transition R-HSA-69275
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Assembly of the pre-replicative complex R-HSA-68867
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic G2-G2/M phases R-HSA-453274
Generic Transcription Pathway R-HSA-212436
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Stabilization of p53 R-HSA-69541
Degradation of GLI2 by the proteasome R-HSA-5610783
RAF/MAP kinase cascade R-HSA-5673001
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 family signaling R-HSA-446652
PTEN Regulation R-HSA-6807070
Deubiquitination R-HSA-5688426
Transcriptional regulation by RUNX1 R-HSA-8878171
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hedgehog 'off' state R-HSA-5610787
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX3 R-HSA-8878159
ABC transporter disorders R-HSA-5619084
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 signaling R-HSA-9020702
Transport of small molecules R-HSA-382551
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Mitotic Metaphase and Anaphase R-HSA-2555396
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular responses to stimuli R-HSA-8953897
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PCP/CE pathway R-HSA-4086400
Intracellular signaling by second messengers R-HSA-9006925
Separation of Sister Chromatids R-HSA-2467813
Nervous system development R-HSA-9675108
Disease R-HSA-1643685
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of AXIN R-HSA-4641257
p53-Dependent G1 DNA Damage Response R-HSA-69563
G1/S Transition R-HSA-69206
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Apoptosis R-HSA-109581
Neddylation R-HSA-8951664
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism R-HSA-1430728
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mitotic cell cycle R-HSA-453276
Mitotic Anaphase R-HSA-68882
Cell Cycle Checkpoints R-HSA-69620
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of beta-catenin by the destruction complex R-HSA-195253
DNA Replication Pre-Initiation R-HSA-69002
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular response to chemical stress R-HSA-9711123
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Beta-catenin independent WNT signaling R-HSA-3858494
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by ROBO receptors R-HSA-376176
G1/S DNA Damage Checkpoints R-HSA-69615
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of Apoptosis R-HSA-169911
ABC-family proteins mediated transport R-HSA-382556
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
HIV Infection R-HSA-162906
TCR signaling R-HSA-202403
Signaling by NOTCH R-HSA-157118
ER-Phagosome pathway R-HSA-1236974
S Phase R-HSA-69242
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
UCH proteinases R-HSA-5689603
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by Interleukins R-HSA-449147
Regulation of RUNX3 expression and activity R-HSA-8941858
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Checkpoints R-HSA-69481
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Programmed Cell Death R-HSA-5357801
Cytokine Signaling in Immune system R-HSA-1280215
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by Hedgehog R-HSA-5358351
MAPK family signaling cascades R-HSA-5683057
KEAP1-NFE2L2 pathway R-HSA-9755511
Hh mutants abrogate ligand secretion R-HSA-5387390
PIP3 activates AKT signaling R-HSA-1257604
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by WNT R-HSA-195721
Hedgehog 'on' state R-HSA-5632684
MAPK1/MAPK3 signaling R-HSA-5684996
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of PTEN stability and activity R-HSA-8948751
Immune System R-HSA-168256
Nuclear events mediated by NFE2L2 R-HSA-9759194
Vif-mediated degradation of APOBEC3G R-HSA-180585
Infectious disease R-HSA-5663205
Cellular responses to stress R-HSA-2262752
Host Interactions of HIV factors R-HSA-162909
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK6/MAPK4 signaling R-HSA-5687128
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
M Phase R-HSA-68886
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Innate Immune System R-HSA-168249
p53-Independent DNA Damage Response R-HSA-69610
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hedgehog 'off' state R-HSA-5610787
Switching of origins to a post-replicative state R-HSA-69052
Metabolism of polyamines R-HSA-351202
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of RUNX2 expression and activity R-HSA-8939902
Hedgehog ligand biogenesis R-HSA-5358346
Infectious disease R-HSA-5663205
DNA Replication R-HSA-69306
Disorders of transmembrane transporters R-HSA-5619115
G2/M Checkpoints R-HSA-69481
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Innate Immune System R-HSA-168249
M Phase R-HSA-68886
Stabilization of p53 R-HSA-69541
G2/M Transition R-HSA-69275
Antigen processing-Cross presentation R-HSA-1236975
Disease R-HSA-1643685
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by NOTCH4 R-HSA-9013694
RNA Polymerase II Transcription R-HSA-73857
Downstream TCR signaling R-HSA-202424
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Gene expression (Transcription) R-HSA-74160
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Developmental Biology R-HSA-1266738
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of Apoptosis R-HSA-169911
Negative regulation of NOTCH4 signaling R-HSA-9604323
Nuclear events mediated by NFE2L2 R-HSA-9759194
TCR signaling R-HSA-202403
Signal Transduction R-HSA-162582
G1/S Transition R-HSA-69206
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cyclin E associated events during G1/S transition R-HSA-69202
Assembly of the pre-replicative complex R-HSA-68867
Class I MHC mediated antigen processing & presentation R-HSA-983169
Adaptive Immune System R-HSA-1280218
Interleukin-1 family signaling R-HSA-446652
Metabolism of amino acids and derivatives R-HSA-71291
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cellular response to chemical stress R-HSA-9711123
Regulation of mitotic cell cycle R-HSA-453276
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular responses to stress R-HSA-2262752
Signaling by Interleukins R-HSA-449147
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by ROBO receptors R-HSA-376176
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Dependent G1 DNA Damage Response R-HSA-69563
Host Interactions of HIV factors R-HSA-162909
Cellular response to hypoxia R-HSA-1234174
Neddylation R-HSA-8951664
Cellular responses to stimuli R-HSA-8953897
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Post-translational protein modification R-HSA-597592
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Anaphase R-HSA-68882
Programmed Cell Death R-HSA-5357801
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Intracellular signaling by second messengers R-HSA-9006925
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
Synthesis of DNA R-HSA-69239
Transport of small molecules R-HSA-382551
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic Metaphase and Anaphase R-HSA-2555396
C-type lectin receptors (CLRs) R-HSA-5621481
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PCP/CE pathway R-HSA-4086400
HIV Infection R-HSA-162906
Hedgehog 'on' state R-HSA-5632684
Asymmetric localization of PCP proteins R-HSA-4608870
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX3 expression and activity R-HSA-8941858
Nervous system development R-HSA-9675108
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCF dependent signaling in response to WNT R-HSA-201681
Axon guidance R-HSA-422475
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by Hedgehog R-HSA-5358351
Metabolism R-HSA-1430728
Vpu mediated degradation of CD4 R-HSA-180534
Beta-catenin independent WNT signaling R-HSA-3858494
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
ABC transporter disorders R-HSA-5619084
Mitotic G2-G2/M phases R-HSA-453274
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of proteins R-HSA-392499
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RAF/MAP kinase cascade R-HSA-5673001
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Orc1 removal from chromatin R-HSA-68949
PTEN Regulation R-HSA-6807070
KEAP1-NFE2L2 pathway R-HSA-9755511
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Apoptosis R-HSA-109581
Signaling by NOTCH R-HSA-157118
Deubiquitination R-HSA-5688426
FCERI mediated NF-kB activation R-HSA-2871837
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cytokine Signaling in Immune system R-HSA-1280215
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of PTEN stability and activity R-HSA-8948751
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
S Phase R-HSA-69242
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle Checkpoints R-HSA-69620
ER-Phagosome pathway R-HSA-1236974
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle R-HSA-1640170
Ub-specific processing proteases R-HSA-5689880
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Immune System R-HSA-168256
DNA Replication Pre-Initiation R-HSA-69002
Degradation of DVL R-HSA-4641258
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by WNT R-HSA-195721
Transcriptional regulation by RUNX1 R-HSA-8878171
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of GLI1 by the proteasome R-HSA-5610780
Interleukin-1 signaling R-HSA-9020702
MAPK family signaling cascades R-HSA-5683057
Vif-mediated degradation of APOBEC3G R-HSA-180585
Neutrophil degranulation R-HSA-6798695
ABC-family proteins mediated transport R-HSA-382556
Metabolism of RNA R-HSA-8953854
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX2 R-HSA-8878166
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S DNA Damage Checkpoints R-HSA-69615
PIP3 activates AKT signaling R-HSA-1257604
Separation of Sister Chromatids R-HSA-2467813
Degradation of AXIN R-HSA-4641257
M Phase R-HSA-68886
Switching of origins to a post-replicative state R-HSA-69052
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular responses to stimuli R-HSA-8953897
Degradation of GLI2 by the proteasome R-HSA-5610783
Interleukin-1 family signaling R-HSA-446652
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'on' state R-HSA-5632684
Regulation of Apoptosis R-HSA-169911
Intracellular signaling by second messengers R-HSA-9006925
Regulation of RUNX2 expression and activity R-HSA-8939902
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Replication Pre-Initiation R-HSA-69002
Adaptive Immune System R-HSA-1280218
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by WNT R-HSA-195721
Class I MHC mediated antigen processing & presentation R-HSA-983169
Apoptosis R-HSA-109581
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
RAF/MAP kinase cascade R-HSA-5673001
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Infectious disease R-HSA-5663205
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
PTEN Regulation R-HSA-6807070
Signal Transduction R-HSA-162582
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
ABC-family proteins mediated transport R-HSA-382556
RNA Polymerase II Transcription R-HSA-73857
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of expression of SLITs and ROBOs R-HSA-9010553
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
G2/M Transition R-HSA-69275
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog 'off' state R-HSA-5610787
Deubiquitination R-HSA-5688426
Degradation of GLI1 by the proteasome R-HSA-5610780
Stabilization of p53 R-HSA-69541
TCF dependent signaling in response to WNT R-HSA-201681
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Transcriptional regulation by RUNX1 R-HSA-8878171
G1/S DNA Damage Checkpoints R-HSA-69615
Nuclear events mediated by NFE2L2 R-HSA-9759194
Mitotic G2-G2/M phases R-HSA-453274
MAPK family signaling cascades R-HSA-5683057
TCR signaling R-HSA-202403
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hh mutants abrogate ligand secretion R-HSA-5387390
Generic Transcription Pathway R-HSA-212436
Mitotic G1 phase and G1/S transition R-HSA-453279
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Vpu mediated degradation of CD4 R-HSA-180534
Separation of Sister Chromatids R-HSA-2467813
Metabolism R-HSA-1430728
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Developmental Biology R-HSA-1266738
CLEC7A (Dectin-1) signaling R-HSA-5607764
Axon guidance R-HSA-422475
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RUNX3 expression and activity R-HSA-8941858
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
HIV Infection R-HSA-162906
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hh mutants are degraded by ERAD R-HSA-5362768
Cytokine Signaling in Immune system R-HSA-1280215
Activation of NF-kappaB in B cells R-HSA-1169091
PIP3 activates AKT signaling R-HSA-1257604
Nervous system development R-HSA-9675108
Regulation of RAS by GAPs R-HSA-5658442
G2/M Checkpoints R-HSA-69481
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of proteins R-HSA-392499
Cellular responses to stress R-HSA-2262752
Signaling by NOTCH4 R-HSA-9013694
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular response to hypoxia R-HSA-1234174
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cyclin E associated events during G1/S transition R-HSA-69202
UCH proteinases R-HSA-5689603
Neutrophil degranulation R-HSA-6798695
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
PCP/CE pathway R-HSA-4086400
Immune System R-HSA-168256
G1/S Transition R-HSA-69206
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle, Mitotic R-HSA-69278
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Independent DNA Damage Response R-HSA-69610
Synthesis of DNA R-HSA-69239
Metabolism of RNA R-HSA-8953854
p53-Dependent G1 DNA Damage Response R-HSA-69563
Transport of small molecules R-HSA-382551
Orc1 removal from chromatin R-HSA-68949
Signaling by Hedgehog R-HSA-5358351
Interleukin-1 signaling R-HSA-9020702
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of DVL R-HSA-4641258
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Assembly of the pre-replicative complex R-HSA-68867
Degradation of AXIN R-HSA-4641257
Cell Cycle Checkpoints R-HSA-69620
C-type lectin receptors (CLRs) R-HSA-5621481
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of PTEN stability and activity R-HSA-8948751
Cell Cycle R-HSA-1640170
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by Interleukins R-HSA-449147
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Downstream TCR signaling R-HSA-202424
Signaling by NOTCH R-HSA-157118
Negative regulation of NOTCH4 signaling R-HSA-9604323
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
S Phase R-HSA-69242
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Anaphase R-HSA-68882
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to chemical stress R-HSA-9711123
Metabolism of amino acids and derivatives R-HSA-71291
MAPK6/MAPK4 signaling R-HSA-5687128
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Gene expression (Transcription) R-HSA-74160
Ub-specific processing proteases R-HSA-5689880
Disorders of transmembrane transporters R-HSA-5619115
Host Interactions of HIV factors R-HSA-162909
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Programmed Cell Death R-HSA-5357801
Metabolism of polyamines R-HSA-351202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Post-translational protein modification R-HSA-597592
Innate Immune System R-HSA-168249
Neddylation R-HSA-8951664
DNA Replication R-HSA-69306
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
ER-Phagosome pathway R-HSA-1236974
Antigen processing-Cross presentation R-HSA-1236975
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by ROBO receptors R-HSA-376176
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of DVL R-HSA-4641258
Nuclear events mediated by NFE2L2 R-HSA-9759194
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stimuli R-HSA-8953897
Infectious disease R-HSA-5663205
Cyclin E associated events during G1/S transition R-HSA-69202
ABC transporter disorders R-HSA-5619084
Signaling by Interleukins R-HSA-449147
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
TCF dependent signaling in response to WNT R-HSA-201681
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Disorders of transmembrane transporters R-HSA-5619115
Signaling by NOTCH4 R-HSA-9013694
Hh mutants abrogate ligand secretion R-HSA-5387390
PTEN Regulation R-HSA-6807070
Signaling by Hedgehog R-HSA-5358351
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic G2-G2/M phases R-HSA-453274
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'on' state R-HSA-5632684
Synthesis of DNA R-HSA-69239
Deubiquitination R-HSA-5688426
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TCR signaling R-HSA-202403
Regulation of RUNX2 expression and activity R-HSA-8939902
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G2/M Checkpoints R-HSA-69481
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Generic Transcription Pathway R-HSA-212436
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Beta-catenin independent WNT signaling R-HSA-3858494
Ub-specific processing proteases R-HSA-5689880
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Switching of origins to a post-replicative state R-HSA-69052
Orc1 removal from chromatin R-HSA-68949
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Programmed Cell Death R-HSA-5357801
M Phase R-HSA-68886
NIK-->noncanonical NF-kB signaling R-HSA-5676590
C-type lectin receptors (CLRs) R-HSA-5621481
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Separation of Sister Chromatids R-HSA-2467813
Assembly of the pre-replicative complex R-HSA-68867
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G1/S DNA Damage Checkpoints R-HSA-69615
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular response to chemical stress R-HSA-9711123
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Independent DNA Damage Response R-HSA-69610
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by NOTCH R-HSA-157118
Hh mutants are degraded by ERAD R-HSA-5362768
Nervous system development R-HSA-9675108
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of RAS by GAPs R-HSA-5658442
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hedgehog 'off' state R-HSA-5610787
Host Interactions of HIV factors R-HSA-162909
Neutrophil degranulation R-HSA-6798695
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
RAF/MAP kinase cascade R-HSA-5673001
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
Vpu mediated degradation of CD4 R-HSA-180534
Signal Transduction R-HSA-162582
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of PTEN stability and activity R-HSA-8948751
Intracellular signaling by second messengers R-HSA-9006925
Gene expression (Transcription) R-HSA-74160
Metabolism of proteins R-HSA-392499
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Adaptive Immune System R-HSA-1280218
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Mitotic Metaphase and Anaphase R-HSA-2555396
HIV Infection R-HSA-162906
Downstream TCR signaling R-HSA-202424
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle, Mitotic R-HSA-69278
ABC-family proteins mediated transport R-HSA-382556
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of Apoptosis R-HSA-169911
Activation of NF-kappaB in B cells R-HSA-1169091
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Axon guidance R-HSA-422475
PCP/CE pathway R-HSA-4086400
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
FCERI mediated NF-kB activation R-HSA-2871837
Developmental Biology R-HSA-1266738
Transport of small molecules R-HSA-382551
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle R-HSA-1640170
Immune System R-HSA-168256
Transcriptional regulation by RUNX2 R-HSA-8878166
ER-Phagosome pathway R-HSA-1236974
Transcriptional regulation by RUNX3 R-HSA-8878159
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog ligand biogenesis R-HSA-5358346
KEAP1-NFE2L2 pathway R-HSA-9755511
MAPK family signaling cascades R-HSA-5683057
Cell Cycle Checkpoints R-HSA-69620
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
DNA Replication Pre-Initiation R-HSA-69002
Degradation of beta-catenin by the destruction complex R-HSA-195253
Innate Immune System R-HSA-168249
Apoptosis R-HSA-109581
Interleukin-1 family signaling R-HSA-446652
DNA Replication R-HSA-69306
Cellular response to hypoxia R-HSA-1234174
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of AXIN R-HSA-4641257
Regulation of RUNX3 expression and activity R-HSA-8941858
Post-translational protein modification R-HSA-597592
Cytokine Signaling in Immune system R-HSA-1280215
UCH proteinases R-HSA-5689603
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signaling by WNT R-HSA-195721
Neddylation R-HSA-8951664
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by ROBO receptors R-HSA-376176
RNA Polymerase II Transcription R-HSA-73857
Metabolism of amino acids and derivatives R-HSA-71291
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism R-HSA-1430728
Interleukin-1 signaling R-HSA-9020702
G2/M Transition R-HSA-69275
G1/S Transition R-HSA-69206
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of polyamines R-HSA-351202
Mitotic Anaphase R-HSA-68882
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Innate Immune System R-HSA-168249
Negative regulation of NOTCH4 signaling R-HSA-9604323
Gene expression (Transcription) R-HSA-74160
Degradation of GLI2 by the proteasome R-HSA-5610783
PTEN Regulation R-HSA-6807070
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by Hedgehog R-HSA-5358351
Interleukin-1 signaling R-HSA-9020702
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signal Transduction R-HSA-162582
MAPK6/MAPK4 signaling R-HSA-5687128
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
S Phase R-HSA-69242
Hh mutants are degraded by ERAD R-HSA-5362768
Transcriptional regulation by RUNX1 R-HSA-8878171
G2/M Transition R-HSA-69275
Hedgehog 'on' state R-HSA-5632684
Mitotic Anaphase R-HSA-68882
Generic Transcription Pathway R-HSA-212436
Regulation of PTEN stability and activity R-HSA-8948751
KEAP1-NFE2L2 pathway R-HSA-9755511
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of proteins R-HSA-392499
Asymmetric localization of PCP proteins R-HSA-4608870
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by NOTCH R-HSA-157118
Metabolism R-HSA-1430728
Cellular response to chemical stress R-HSA-9711123
Hedgehog ligand biogenesis R-HSA-5358346
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI1 by the proteasome R-HSA-5610780
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by WNT R-HSA-195721
Regulation of mitotic cell cycle R-HSA-453276
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Switching of origins to a post-replicative state R-HSA-69052
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
Separation of Sister Chromatids R-HSA-2467813
Disease R-HSA-1643685
Cell Cycle, Mitotic R-HSA-69278
Developmental Biology R-HSA-1266738
Synthesis of DNA R-HSA-69239
PCP/CE pathway R-HSA-4086400
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S Transition R-HSA-69206
Antigen processing-Cross presentation R-HSA-1236975
Class I MHC mediated antigen processing & presentation R-HSA-983169
Immune System R-HSA-168256
Nervous system development R-HSA-9675108
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
M Phase R-HSA-68886
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transcriptional regulation by RUNX2 R-HSA-8878166
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
TCR signaling R-HSA-202403
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Stabilization of p53 R-HSA-69541
Orc1 removal from chromatin R-HSA-68949
Downstream TCR signaling R-HSA-202424
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Independent DNA Damage Response R-HSA-69610
Cytokine Signaling in Immune system R-HSA-1280215
Intracellular signaling by second messengers R-HSA-9006925
RAF/MAP kinase cascade R-HSA-5673001
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of Apoptosis R-HSA-169911
Cyclin E associated events during G1/S transition R-HSA-69202
Deubiquitination R-HSA-5688426
G1/S DNA Damage Checkpoints R-HSA-69615
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of RAS by GAPs R-HSA-5658442
UCH proteinases R-HSA-5689603
Infectious disease R-HSA-5663205
Neutrophil degranulation R-HSA-6798695
Nuclear events mediated by NFE2L2 R-HSA-9759194
Ub-specific processing proteases R-HSA-5689880
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication R-HSA-69306
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK family signaling cascades R-HSA-5683057
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Transport of small molecules R-HSA-382551
Hedgehog 'off' state R-HSA-5610787
Post-translational protein modification R-HSA-597592
Assembly of the pre-replicative complex R-HSA-68867
C-type lectin receptors (CLRs) R-HSA-5621481
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular responses to stress R-HSA-2262752
Degradation of beta-catenin by the destruction complex R-HSA-195253
Axon guidance R-HSA-422475
Interleukin-1 family signaling R-HSA-446652
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Adaptive Immune System R-HSA-1280218
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of DVL R-HSA-4641258
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stimuli R-HSA-8953897
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by NOTCH4 R-HSA-9013694
MAPK1/MAPK3 signaling R-HSA-5684996
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ER-Phagosome pathway R-HSA-1236974
ABC-family proteins mediated transport R-HSA-382556
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of AXIN R-HSA-4641257
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of polyamines R-HSA-351202
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic Metaphase and Anaphase R-HSA-2555396
HIV Infection R-HSA-162906
Metabolism of RNA R-HSA-8953854
TCF dependent signaling in response to WNT R-HSA-201681
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
DNA Replication Pre-Initiation R-HSA-69002
Activation of NF-kappaB in B cells R-HSA-1169091
G2/M Checkpoints R-HSA-69481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of RUNX2 expression and activity R-HSA-8939902
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
PIP3 activates AKT signaling R-HSA-1257604
Neddylation R-HSA-8951664
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle Checkpoints R-HSA-69620
Beta-catenin independent WNT signaling R-HSA-3858494
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by ROBO receptors R-HSA-376176
Mitotic G1 phase and G1/S transition R-HSA-453279
Disorders of transmembrane transporters R-HSA-5619115
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by Interleukins R-HSA-449147
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by WNT R-HSA-195721
MAPK family signaling cascades R-HSA-5683057
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'off' state R-HSA-5610787
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
KEAP1-NFE2L2 pathway R-HSA-9755511
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX3 R-HSA-8878159
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stimuli R-HSA-8953897
Metabolism R-HSA-1430728
Degradation of DVL R-HSA-4641258
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cell Cycle, Mitotic R-HSA-69278
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Disease R-HSA-1643685
Axon guidance R-HSA-422475
RAF/MAP kinase cascade R-HSA-5673001
Cytokine Signaling in Immune system R-HSA-1280215
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog ligand biogenesis R-HSA-5358346
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Adaptive Immune System R-HSA-1280218
Hedgehog 'on' state R-HSA-5632684
Nuclear events mediated by NFE2L2 R-HSA-9759194
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
Cyclin E associated events during G1/S transition R-HSA-69202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic Metaphase and Anaphase R-HSA-2555396
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of RUNX2 expression and activity R-HSA-8939902
UCH proteinases R-HSA-5689603
Transcriptional regulation by RUNX1 R-HSA-8878171
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hh mutants are degraded by ERAD R-HSA-5362768
Signal Transduction R-HSA-162582
G1/S Transition R-HSA-69206
Deubiquitination R-HSA-5688426
Developmental Biology R-HSA-1266738
Interleukin-1 family signaling R-HSA-446652
ABC transporter disorders R-HSA-5619084
Cellular response to chemical stress R-HSA-9711123
TCR signaling R-HSA-202403
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
MAPK1/MAPK3 signaling R-HSA-5684996
C-type lectin receptors (CLRs) R-HSA-5621481
G2/M Transition R-HSA-69275
Assembly of the pre-replicative complex R-HSA-68867
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of RAS by GAPs R-HSA-5658442
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Immune System R-HSA-168256
Stabilization of p53 R-HSA-69541
Signaling by NOTCH R-HSA-157118
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of AXIN R-HSA-4641257
Synthesis of DNA R-HSA-69239
Generic Transcription Pathway R-HSA-212436
Post-translational protein modification R-HSA-597592
FCERI mediated NF-kB activation R-HSA-2871837
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of proteins R-HSA-392499
RNA Polymerase II Transcription R-HSA-73857
Signaling by Interleukins R-HSA-449147
Neddylation R-HSA-8951664
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic G1 phase and G1/S transition R-HSA-453279
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 signaling R-HSA-9020702
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Neutrophil degranulation R-HSA-6798695
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Vpu mediated degradation of CD4 R-HSA-180534
Apoptosis R-HSA-109581
Signaling by NOTCH4 R-HSA-9013694
Nervous system development R-HSA-9675108
Mitotic Anaphase R-HSA-68882
HIV Infection R-HSA-162906
Orc1 removal from chromatin R-HSA-68949
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of RNA R-HSA-8953854
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by ROBO receptors R-HSA-376176
Infectious disease R-HSA-5663205
Switching of origins to a post-replicative state R-HSA-69052
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of polyamines R-HSA-351202
Cell Cycle R-HSA-1640170
Cell Cycle Checkpoints R-HSA-69620
Regulation of mitotic cell cycle R-HSA-453276
S Phase R-HSA-69242
Ub-specific processing proteases R-HSA-5689880
Host Interactions of HIV factors R-HSA-162909
Downstream TCR signaling R-HSA-202424
Separation of Sister Chromatids R-HSA-2467813
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Programmed Cell Death R-HSA-5357801
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of GLI2 by the proteasome R-HSA-5610783
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of RUNX3 expression and activity R-HSA-8941858
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
PCP/CE pathway R-HSA-4086400
G1/S DNA Damage Checkpoints R-HSA-69615
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
MAPK6/MAPK4 signaling R-HSA-5687128
M Phase R-HSA-68886
Regulation of Apoptosis R-HSA-169911
DNA Replication Pre-Initiation R-HSA-69002
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Vif-mediated degradation of APOBEC3G R-HSA-180585
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Mitotic G2-G2/M phases R-HSA-453274
Signaling by Hedgehog R-HSA-5358351
Degradation of GLI1 by the proteasome R-HSA-5610780
Disorders of transmembrane transporters R-HSA-5619115
Degradation of beta-catenin by the destruction complex R-HSA-195253
ER-Phagosome pathway R-HSA-1236974
Transport of small molecules R-HSA-382551
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
TCF dependent signaling in response to WNT R-HSA-201681
Antigen processing-Cross presentation R-HSA-1236975
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
G2/M Checkpoints R-HSA-69481
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX2 expression and activity R-HSA-8939902
S Phase R-HSA-69242
PTEN Regulation R-HSA-6807070
Interleukin-1 family signaling R-HSA-446652
Antigen processing-Cross presentation R-HSA-1236975
Separation of Sister Chromatids R-HSA-2467813
Regulation of mitotic cell cycle R-HSA-453276
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
PIP3 activates AKT signaling R-HSA-1257604
Cyclin E associated events during G1/S transition R-HSA-69202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
HIV Infection R-HSA-162906
Orc1 removal from chromatin R-HSA-68949
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by Hedgehog R-HSA-5358351
Hedgehog 'on' state R-HSA-5632684
RNA Polymerase II Transcription R-HSA-73857
Disease R-HSA-1643685
Regulation of Apoptosis R-HSA-169911
Degradation of beta-catenin by the destruction complex R-HSA-195253
Nuclear events mediated by NFE2L2 R-HSA-9759194
Gene expression (Transcription) R-HSA-74160
PCP/CE pathway R-HSA-4086400
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G1/S Transition R-HSA-69206
Immune System R-HSA-168256
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Asymmetric localization of PCP proteins R-HSA-4608870
Infectious disease R-HSA-5663205
Transport of small molecules R-HSA-382551
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication R-HSA-69306
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular response to hypoxia R-HSA-1234174
Switching of origins to a post-replicative state R-HSA-69052
Degradation of DVL R-HSA-4641258
RAF/MAP kinase cascade R-HSA-5673001
p53-Independent DNA Damage Response R-HSA-69610
Transcriptional regulation by RUNX3 R-HSA-8878159
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of RAS by GAPs R-HSA-5658442
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Synthesis of DNA R-HSA-69239
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G2/M Checkpoints R-HSA-69481
Hh mutants abrogate ligand secretion R-HSA-5387390
TCR signaling R-HSA-202403
Metabolism R-HSA-1430728
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic Anaphase R-HSA-68882
Metabolism of polyamines R-HSA-351202
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular responses to stimuli R-HSA-8953897
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
UCH proteinases R-HSA-5689603
Stabilization of p53 R-HSA-69541
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Deubiquitination R-HSA-5688426
Activation of NF-kappaB in B cells R-HSA-1169091
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
Defective CFTR causes cystic fibrosis R-HSA-5678895
Adaptive Immune System R-HSA-1280218
Ub-specific processing proteases R-HSA-5689880
Programmed Cell Death R-HSA-5357801
Assembly of the pre-replicative complex R-HSA-68867
Regulation of RUNX3 expression and activity R-HSA-8941858
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G2-G2/M phases R-HSA-453274
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G2/M Transition R-HSA-69275
Mitotic G1 phase and G1/S transition R-HSA-453279
Disorders of transmembrane transporters R-HSA-5619115
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by ROBO receptors R-HSA-376176
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of AXIN R-HSA-4641257
Hedgehog ligand biogenesis R-HSA-5358346
M Phase R-HSA-68886
Cellular response to chemical stress R-HSA-9711123
TCF dependent signaling in response to WNT R-HSA-201681
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cell Cycle Checkpoints R-HSA-69620
Neddylation R-HSA-8951664
Hedgehog 'off' state R-HSA-5610787
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of PTEN stability and activity R-HSA-8948751
Transcriptional regulation by RUNX2 R-HSA-8878166
Vif-mediated degradation of APOBEC3G R-HSA-180585
MAPK6/MAPK4 signaling R-HSA-5687128
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interleukin-1 signaling R-HSA-9020702
Nervous system development R-HSA-9675108
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
C-type lectin receptors (CLRs) R-HSA-5621481
Developmental Biology R-HSA-1266738
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by NOTCH R-HSA-157118
Cell Cycle R-HSA-1640170
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Intracellular signaling by second messengers R-HSA-9006925
Apoptosis R-HSA-109581
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by Interleukins R-HSA-449147
DNA Replication Pre-Initiation R-HSA-69002
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
ER-Phagosome pathway R-HSA-1236974
Cell Cycle, Mitotic R-HSA-69278
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
KEAP1-NFE2L2 pathway R-HSA-9755511
Generic Transcription Pathway R-HSA-212436
Degradation of GLI2 by the proteasome R-HSA-5610783
Post-translational protein modification R-HSA-597592
Downstream TCR signaling R-HSA-202424
Neutrophil degranulation R-HSA-6798695
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by WNT R-HSA-195721
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of RNA R-HSA-8953854
Signaling by NOTCH4 R-HSA-9013694
ABC-family proteins mediated transport R-HSA-382556
Host Interactions of HIV factors R-HSA-162909
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of proteins R-HSA-392499
Axon guidance R-HSA-422475
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of RUNX3 expression and activity R-HSA-8941858
Immune System R-HSA-168256
Signaling by NOTCH R-HSA-157118
Degradation of GLI2 by the proteasome R-HSA-5610783
TCR signaling R-HSA-202403
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Synthesis of DNA R-HSA-69239
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
DNA Replication R-HSA-69306
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Transition R-HSA-69275
Axon guidance R-HSA-422475
Cell Cycle R-HSA-1640170
Signaling by Hedgehog R-HSA-5358351
Mitotic Anaphase R-HSA-68882
Cellular responses to stress R-HSA-2262752
RNA Polymerase II Transcription R-HSA-73857
Downstream TCR signaling R-HSA-202424
ABC-family proteins mediated transport R-HSA-382556
HIV Infection R-HSA-162906
Cell Cycle, Mitotic R-HSA-69278
Separation of Sister Chromatids R-HSA-2467813
S Phase R-HSA-69242
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of beta-catenin by the destruction complex R-HSA-195253
Asymmetric localization of PCP proteins R-HSA-4608870
Beta-catenin independent WNT signaling R-HSA-3858494
PTEN Regulation R-HSA-6807070
Adaptive Immune System R-HSA-1280218
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular response to hypoxia R-HSA-1234174
Hh mutants abrogate ligand secretion R-HSA-5387390
Disorders of transmembrane transporters R-HSA-5619115
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism R-HSA-1430728
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent DNA Damage Response R-HSA-69610
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Gene expression (Transcription) R-HSA-74160
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PCP/CE pathway R-HSA-4086400
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1 DNA Damage Response R-HSA-69563
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
DNA Replication Pre-Initiation R-HSA-69002
Interleukin-1 family signaling R-HSA-446652
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ub-specific processing proteases R-HSA-5689880
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Mitotic G2-G2/M phases R-HSA-453274
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cyclin E associated events during G1/S transition R-HSA-69202
Switching of origins to a post-replicative state R-HSA-69052
Degradation of DVL R-HSA-4641258
RAF/MAP kinase cascade R-HSA-5673001
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
KEAP1-NFE2L2 pathway R-HSA-9755511
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by NOTCH4 R-HSA-9013694
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Post-translational protein modification R-HSA-597592
Nervous system development R-HSA-9675108
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cell Cycle Checkpoints R-HSA-69620
MAPK1/MAPK3 signaling R-HSA-5684996
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signal Transduction R-HSA-162582
Regulation of RAS by GAPs R-HSA-5658442
TCF dependent signaling in response to WNT R-HSA-201681
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Interleukin-1 signaling R-HSA-9020702
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic Metaphase and Anaphase R-HSA-2555396
G2/M Checkpoints R-HSA-69481
Deubiquitination R-HSA-5688426
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Host Interactions of HIV factors R-HSA-162909
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX3 R-HSA-8878159
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by ROBO receptors R-HSA-376176
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
Programmed Cell Death R-HSA-5357801
Hh mutants are degraded by ERAD R-HSA-5362768
Infectious disease R-HSA-5663205
Regulation of PTEN stability and activity R-HSA-8948751
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
Developmental Biology R-HSA-1266738
Regulation of mitotic cell cycle R-HSA-453276
Transcriptional regulation by RUNX2 R-HSA-8878166
FCERI mediated NF-kB activation R-HSA-2871837
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
PIP3 activates AKT signaling R-HSA-1257604
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
Regulation of Apoptosis R-HSA-169911
Orc1 removal from chromatin R-HSA-68949
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transport of small molecules R-HSA-382551
Activation of NF-kappaB in B cells R-HSA-1169091
Apoptosis R-HSA-109581
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Degradation of GLI1 by the proteasome R-HSA-5610780
M Phase R-HSA-68886
Defective CFTR causes cystic fibrosis R-HSA-5678895
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RUNX2 expression and activity R-HSA-8939902
Vif-mediated degradation of APOBEC3G R-HSA-180585
Stabilization of p53 R-HSA-69541
Hedgehog 'on' state R-HSA-5632684
Assembly of the pre-replicative complex R-HSA-68867
Neddylation R-HSA-8951664
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disease R-HSA-1643685
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog ligand biogenesis R-HSA-5358346
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by WNT R-HSA-195721
Cellular responses to stimuli R-HSA-8953897
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Innate Immune System R-HSA-168249
Metabolism of polyamines R-HSA-351202
Neutrophil degranulation R-HSA-6798695
ABC transporter disorders R-HSA-5619084
MAPK family signaling cascades R-HSA-5683057
Hedgehog 'off' state R-HSA-5610787
Class I MHC mediated antigen processing & presentation R-HSA-983169
Vpu mediated degradation of CD4 R-HSA-180534
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by Interleukins R-HSA-449147
Degradation of AXIN R-HSA-4641257
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hh mutants abrogate ligand secretion R-HSA-5387390
Signaling by the B Cell Receptor (BCR) R-HSA-983705
S Phase R-HSA-69242
DNA Replication Pre-Initiation R-HSA-69002
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Hedgehog 'on' state R-HSA-5632684
Regulation of PTEN stability and activity R-HSA-8948751
Vpu mediated degradation of CD4 R-HSA-180534
Generic Transcription Pathway R-HSA-212436
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by Hedgehog R-HSA-5358351
Nuclear events mediated by NFE2L2 R-HSA-9759194
Transcriptional regulation by RUNX3 R-HSA-8878159
MAPK1/MAPK3 signaling R-HSA-5684996
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of GLI1 by the proteasome R-HSA-5610780
Hedgehog 'off' state R-HSA-5610787
HIV Infection R-HSA-162906
Gene expression (Transcription) R-HSA-74160
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ub-specific processing proteases R-HSA-5689880
Regulation of mitotic cell cycle R-HSA-453276
Signaling by WNT R-HSA-195721
Cellular response to chemical stress R-HSA-9711123
Apoptosis R-HSA-109581
Metabolism of RNA R-HSA-8953854
PIP3 activates AKT signaling R-HSA-1257604
TCF dependent signaling in response to WNT R-HSA-201681
Orc1 removal from chromatin R-HSA-68949
Transport of small molecules R-HSA-382551
Programmed Cell Death R-HSA-5357801
Interleukin-1 signaling R-HSA-9020702
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Assembly of the pre-replicative complex R-HSA-68867
Signaling by NOTCH4 R-HSA-9013694
Mitotic Metaphase and Anaphase R-HSA-2555396
Interleukin-1 family signaling R-HSA-446652
Degradation of AXIN R-HSA-4641257
M Phase R-HSA-68886
ABC transporter disorders R-HSA-5619084
Cytokine Signaling in Immune system R-HSA-1280215
FCERI mediated NF-kB activation R-HSA-2871837
Separation of Sister Chromatids R-HSA-2467813
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Dependent G1 DNA Damage Response R-HSA-69563
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
G1/S Transition R-HSA-69206
Cell Cycle Checkpoints R-HSA-69620
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of amino acids and derivatives R-HSA-71291
Disorders of transmembrane transporters R-HSA-5619115
Asymmetric localization of PCP proteins R-HSA-4608870
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by NOTCH R-HSA-157118
Defective CFTR causes cystic fibrosis R-HSA-5678895
Neutrophil degranulation R-HSA-6798695
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of DVL R-HSA-4641258
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle R-HSA-1640170
Downstream TCR signaling R-HSA-202424
RAF/MAP kinase cascade R-HSA-5673001
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cellular responses to stress R-HSA-2262752
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Metabolism of polyamines R-HSA-351202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Axon guidance R-HSA-422475
PCP/CE pathway R-HSA-4086400
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular response to hypoxia R-HSA-1234174
Immune System R-HSA-168256
G2/M Checkpoints R-HSA-69481
Regulation of RAS by GAPs R-HSA-5658442
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Disease R-HSA-1643685
Hedgehog ligand biogenesis R-HSA-5358346
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Switching of origins to a post-replicative state R-HSA-69052
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
Post-translational protein modification R-HSA-597592
Cellular responses to stimuli R-HSA-8953897
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Deubiquitination R-HSA-5688426
Degradation of GLI2 by the proteasome R-HSA-5610783
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Vif-mediated degradation of APOBEC3G R-HSA-180585
Host Interactions of HIV factors R-HSA-162909
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism R-HSA-1430728
Adaptive Immune System R-HSA-1280218
Intracellular signaling by second messengers R-HSA-9006925
Regulation of Apoptosis R-HSA-169911
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Developmental Biology R-HSA-1266738
G1/S DNA Damage Checkpoints R-HSA-69615
KEAP1-NFE2L2 pathway R-HSA-9755511
DNA Replication R-HSA-69306
Nervous system development R-HSA-9675108
Mitotic Anaphase R-HSA-68882
C-type lectin receptors (CLRs) R-HSA-5621481
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signal Transduction R-HSA-162582
ER-Phagosome pathway R-HSA-1236974
p53-Independent DNA Damage Response R-HSA-69610
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
PTEN Regulation R-HSA-6807070
Stabilization of p53 R-HSA-69541
G2/M Transition R-HSA-69275
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RUNX2 expression and activity R-HSA-8939902
UCH proteinases R-HSA-5689603
Metabolism of proteins R-HSA-392499
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCR signaling R-HSA-202403
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by ROBO receptors R-HSA-376176
Signaling by Interleukins R-HSA-449147
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK family signaling cascades R-HSA-5683057
Cell Cycle, Mitotic R-HSA-69278
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
ABC-family proteins mediated transport R-HSA-382556
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of NF-kappaB in B cells R-HSA-1169091
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants are degraded by ERAD R-HSA-5362768
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Beta-catenin independent WNT signaling R-HSA-3858494
Antigen processing-Cross presentation R-HSA-1236975
Transcriptional regulation by RUNX1 R-HSA-8878171
RNA Polymerase II Transcription R-HSA-73857
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX2 R-HSA-8878166

Expression Atlas ENSG00000136930
NCBI gene (formerly Entrezgene) 5695
GeneCards 9544
HGNC Symbol HGNC:9544
MIM gene 604030
UniProtKB Gene Name Q99436
WikiGene 5695
Gene: ADRM1
Ensembl ID : ENSG00000130706
Description: ADRM1 26S proteasome ubiquitin receptor
Gene Synonyms: ARM1,GP110,PSMD16,RPN13
5 APIs:
261 Possible Orthologues:

Post-translational protein modification R-HSA-597592
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Deubiquitination R-HSA-5688426
UCH proteinases R-HSA-5689603
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
Deubiquitination R-HSA-5688426
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
Metabolism of proteins R-HSA-392499
Ub-specific processing proteases R-HSA-5689880
UCH proteinases R-HSA-5689603
Deubiquitination R-HSA-5688426
Post-translational protein modification R-HSA-597592
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Metabolism of proteins R-HSA-392499
UCH proteinases R-HSA-5689603
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
UCH proteinases R-HSA-5689603
Post-translational protein modification R-HSA-597592
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Ub-specific processing proteases R-HSA-5689880
Deubiquitination R-HSA-5688426
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
Deubiquitination R-HSA-5688426
Metabolism of proteins R-HSA-392499
UCH proteinases R-HSA-5689603
Ub-specific processing proteases R-HSA-5689880
Post-translational protein modification R-HSA-597592
Deubiquitination R-HSA-5688426
Metabolism of proteins R-HSA-392499
Ub-specific processing proteases R-HSA-5689880
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
Post-translational protein modification R-HSA-597592
Ub-specific processing proteases R-HSA-5689880
UCH proteinases R-HSA-5689603
Metabolism of proteins R-HSA-392499
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Deubiquitination R-HSA-5688426
UCH proteinases R-HSA-5689603
Post-translational protein modification R-HSA-597592

Expression Atlas ENSG00000130706
NCBI gene (formerly Entrezgene) 11047
GeneCards 15759
HGNC Symbol HGNC:15759
MIM gene 610650
UniProtKB Gene Name Q16186
WikiGene 11047
Gene: PSMA2
Ensembl ID : ENSG00000106588
Description: proteasome 20S subunit alpha 2
Gene Synonyms: HC3,MU,PMSA2
6 APIs:
231 Possible Orthologues:

Metabolism R-HSA-1430728
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by NOTCH4 R-HSA-9013694
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Disease R-HSA-1643685
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Metabolism of proteins R-HSA-392499
Signaling by NOTCH R-HSA-157118
Regulation of Apoptosis R-HSA-169911
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of DVL R-HSA-4641258
Activation of NF-kappaB in B cells R-HSA-1169091
Cytokine Signaling in Immune system R-HSA-1280215
Cellular responses to stimuli R-HSA-8953897
ABC transporter disorders R-HSA-5619084
UCH proteinases R-HSA-5689603
Cellular responses to stress R-HSA-2262752
Regulation of PTEN stability and activity R-HSA-8948751
MAPK6/MAPK4 signaling R-HSA-5687128
Host Interactions of HIV factors R-HSA-162909
RAF/MAP kinase cascade R-HSA-5673001
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of GLI1 by the proteasome R-HSA-5610780
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Downstream TCR signaling R-HSA-202424
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of mitotic cell cycle R-HSA-453276
Innate Immune System R-HSA-168249
Ub-specific processing proteases R-HSA-5689880
Vpu mediated degradation of CD4 R-HSA-180534
G1/S DNA Damage Checkpoints R-HSA-69615
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PCP/CE pathway R-HSA-4086400
DNA Replication R-HSA-69306
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signal Transduction R-HSA-162582
Hedgehog 'off' state R-HSA-5610787
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Defective CFTR causes cystic fibrosis R-HSA-5678895
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of GLI2 by the proteasome R-HSA-5610783
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FCERI mediated NF-kB activation R-HSA-2871837
TCF dependent signaling in response to WNT R-HSA-201681
MAPK family signaling cascades R-HSA-5683057
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Immune System R-HSA-168256
Neddylation R-HSA-8951664
Adaptive Immune System R-HSA-1280218
p53-Independent DNA Damage Response R-HSA-69610
Signaling by ROBO receptors R-HSA-376176
Developmental Biology R-HSA-1266738
Signaling by Interleukins R-HSA-449147
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Synthesis of DNA R-HSA-69239
ER-Phagosome pathway R-HSA-1236974
Disorders of transmembrane transporters R-HSA-5619115
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cell Cycle, Mitotic R-HSA-69278
Apoptosis R-HSA-109581
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of polyamines R-HSA-351202
Post-translational protein modification R-HSA-597592
Signaling by WNT R-HSA-195721
PIP3 activates AKT signaling R-HSA-1257604
S Phase R-HSA-69242
Assembly of the pre-replicative complex R-HSA-68867
Gene expression (Transcription) R-HSA-74160
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RUNX3 expression and activity R-HSA-8941858
Neutrophil degranulation R-HSA-6798695
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic Anaphase R-HSA-68882
Mitotic G2-G2/M phases R-HSA-453274
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX1 R-HSA-8878171
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX2 R-HSA-8878166
Intracellular signaling by second messengers R-HSA-9006925
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of RAS by GAPs R-HSA-5658442
Infectious disease R-HSA-5663205
Metabolism of RNA R-HSA-8953854
Transport of small molecules R-HSA-382551
Degradation of AXIN R-HSA-4641257
G2/M Transition R-HSA-69275
Antigen processing-Cross presentation R-HSA-1236975
Programmed Cell Death R-HSA-5357801
PTEN Regulation R-HSA-6807070
Nuclear events mediated by NFE2L2 R-HSA-9759194
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
ABC-family proteins mediated transport R-HSA-382556
G1/S Transition R-HSA-69206
Class I MHC mediated antigen processing & presentation R-HSA-983169
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular response to hypoxia R-HSA-1234174
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
HIV Infection R-HSA-162906
Transcriptional regulation by RUNX3 R-HSA-8878159
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by Hedgehog R-HSA-5358351
Hh mutants are degraded by ERAD R-HSA-5362768
Nervous system development R-HSA-9675108
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cellular response to chemical stress R-HSA-9711123
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
M Phase R-HSA-68886
Metabolism R-HSA-1430728
G2/M Checkpoints R-HSA-69481
Orc1 removal from chromatin R-HSA-68949
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog 'on' state R-HSA-5632684
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle Checkpoints R-HSA-69620
RNA Polymerase II Transcription R-HSA-73857
DNA Replication Pre-Initiation R-HSA-69002
Stabilization of p53 R-HSA-69541
Axon guidance R-HSA-422475
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism of amino acids and derivatives R-HSA-71291
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 signaling R-HSA-9020702
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Deubiquitination R-HSA-5688426
Interleukin-1 family signaling R-HSA-446652
TCR signaling R-HSA-202403
Regulation of RUNX2 expression and activity R-HSA-8939902
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Separation of Sister Chromatids R-HSA-2467813
Asymmetric localization of PCP proteins R-HSA-4608870
Degradation of beta-catenin by the destruction complex R-HSA-195253
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Degradation of AXIN R-HSA-4641257
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Beta-catenin independent WNT signaling R-HSA-3858494
Post-translational protein modification R-HSA-597592
Axon guidance R-HSA-422475
Signaling by Hedgehog R-HSA-5358351
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Host Interactions of HIV factors R-HSA-162909
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cell Cycle R-HSA-1640170
TCF dependent signaling in response to WNT R-HSA-201681
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Vpu mediated degradation of CD4 R-HSA-180534
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Asymmetric localization of PCP proteins R-HSA-4608870
Neddylation R-HSA-8951664
p53-Independent DNA Damage Response R-HSA-69610
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of PTEN stability and activity R-HSA-8948751
G1/S DNA Damage Checkpoints R-HSA-69615
TCR signaling R-HSA-202403
MAPK6/MAPK4 signaling R-HSA-5687128
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Assembly of the pre-replicative complex R-HSA-68867
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transport of small molecules R-HSA-382551
Metabolism of RNA R-HSA-8953854
ABC-family proteins mediated transport R-HSA-382556
ER-Phagosome pathway R-HSA-1236974
Hedgehog 'off' state R-HSA-5610787
Signaling by WNT R-HSA-195721
Metabolism of amino acids and derivatives R-HSA-71291
Separation of Sister Chromatids R-HSA-2467813
Gene expression (Transcription) R-HSA-74160
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RAS by GAPs R-HSA-5658442
Infectious disease R-HSA-5663205
Cellular response to hypoxia R-HSA-1234174
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH4 R-HSA-9013694
Cell Cycle, Mitotic R-HSA-69278
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cytokine Signaling in Immune system R-HSA-1280215
C-type lectin receptors (CLRs) R-HSA-5621481
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of beta-catenin by the destruction complex R-HSA-195253
DNA Replication R-HSA-69306
M Phase R-HSA-68886
Nuclear events mediated by NFE2L2 R-HSA-9759194
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of DVL R-HSA-4641258
Activation of NF-kappaB in B cells R-HSA-1169091
Innate Immune System R-HSA-168249
Apoptosis R-HSA-109581
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CLEC7A (Dectin-1) signaling R-HSA-5607764
S Phase R-HSA-69242
UCH proteinases R-HSA-5689603
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
FCERI mediated NF-kB activation R-HSA-2871837
PIP3 activates AKT signaling R-HSA-1257604
Downstream TCR signaling R-HSA-202424
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Synthesis of DNA R-HSA-69239
Regulation of Apoptosis R-HSA-169911
Regulation of expression of SLITs and ROBOs R-HSA-9010553
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Intracellular signaling by second messengers R-HSA-9006925
Orc1 removal from chromatin R-HSA-68949
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of RUNX3 expression and activity R-HSA-8941858
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Adaptive Immune System R-HSA-1280218
Metabolism of proteins R-HSA-392499
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Cellular responses to stress R-HSA-2262752
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
ABC transporter disorders R-HSA-5619084
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK family signaling cascades R-HSA-5683057
G2/M Transition R-HSA-69275
MAPK1/MAPK3 signaling R-HSA-5684996
PTEN Regulation R-HSA-6807070
Cellular responses to stimuli R-HSA-8953897
Mitotic Anaphase R-HSA-68882
KEAP1-NFE2L2 pathway R-HSA-9755511
Hedgehog 'on' state R-HSA-5632684
Vif-mediated degradation of APOBEC3G R-HSA-180585
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing-Cross presentation R-HSA-1236975
Signaling by Interleukins R-HSA-449147
Transcriptional regulation by RUNX1 R-HSA-8878171
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX2 R-HSA-8878166
Hh mutants abrogate ligand secretion R-HSA-5387390
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signal Transduction R-HSA-162582
Degradation of GLI1 by the proteasome R-HSA-5610780
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Interleukin-1 signaling R-HSA-9020702
DNA Replication Pre-Initiation R-HSA-69002
Neutrophil degranulation R-HSA-6798695
Ub-specific processing proteases R-HSA-5689880
Switching of origins to a post-replicative state R-HSA-69052
Nervous system development R-HSA-9675108
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 family signaling R-HSA-446652
Cyclin E associated events during G1/S transition R-HSA-69202
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants are degraded by ERAD R-HSA-5362768
Deubiquitination R-HSA-5688426
Signaling by ROBO receptors R-HSA-376176
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
HIV Infection R-HSA-162906
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S Transition R-HSA-69206
PCP/CE pathway R-HSA-4086400
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle Checkpoints R-HSA-69620
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of polyamines R-HSA-351202
Degradation of GLI2 by the proteasome R-HSA-5610783
Immune System R-HSA-168256
Hedgehog ligand biogenesis R-HSA-5358346
G2/M Checkpoints R-HSA-69481
RNA Polymerase II Transcription R-HSA-73857
Cellular response to chemical stress R-HSA-9711123
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by NOTCH R-HSA-157118
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
TCR signaling R-HSA-202403
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Beta-catenin independent WNT signaling R-HSA-3858494
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of RNA R-HSA-8953854
Separation of Sister Chromatids R-HSA-2467813
Adaptive Immune System R-HSA-1280218
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of mitotic cell cycle R-HSA-453276
PIP3 activates AKT signaling R-HSA-1257604
Infectious disease R-HSA-5663205
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of expression of SLITs and ROBOs R-HSA-9010553
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Axon guidance R-HSA-422475
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by WNT R-HSA-195721
Metabolism of polyamines R-HSA-351202
RAF/MAP kinase cascade R-HSA-5673001
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK family signaling cascades R-HSA-5683057
Developmental Biology R-HSA-1266738
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Neddylation R-HSA-8951664
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog 'off' state R-HSA-5610787
Metabolism of amino acids and derivatives R-HSA-71291
Disorders of transmembrane transporters R-HSA-5619115
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Nuclear events mediated by NFE2L2 R-HSA-9759194
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G2/M Checkpoints R-HSA-69481
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of proteins R-HSA-392499
Cellular response to chemical stress R-HSA-9711123
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
Disease R-HSA-1643685
Downstream TCR signaling R-HSA-202424
Mitotic G2-G2/M phases R-HSA-453274
Mitotic G1 phase and G1/S transition R-HSA-453279
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
p53-Independent DNA Damage Response R-HSA-69610
Vif-mediated degradation of APOBEC3G R-HSA-180585
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
HIV Infection R-HSA-162906
Transcriptional regulation by RUNX2 R-HSA-8878166
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of GLI2 by the proteasome R-HSA-5610783
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Synthesis of DNA R-HSA-69239
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Transport of small molecules R-HSA-382551
Signaling by NOTCH4 R-HSA-9013694
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
PTEN Regulation R-HSA-6807070
Post-translational protein modification R-HSA-597592
Intracellular signaling by second messengers R-HSA-9006925
CLEC7A (Dectin-1) signaling R-HSA-5607764
UCH proteinases R-HSA-5689603
Immune System R-HSA-168256
Antigen processing-Cross presentation R-HSA-1236975
Defective CFTR causes cystic fibrosis R-HSA-5678895
Innate Immune System R-HSA-168249
TCF dependent signaling in response to WNT R-HSA-201681
DNA Replication Pre-Initiation R-HSA-69002
Switching of origins to a post-replicative state R-HSA-69052
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
ABC-family proteins mediated transport R-HSA-382556
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Nervous system development R-HSA-9675108
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of Apoptosis R-HSA-169911
S Phase R-HSA-69242
Interleukin-1 family signaling R-HSA-446652
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
KEAP1-NFE2L2 pathway R-HSA-9755511
Interleukin-1 signaling R-HSA-9020702
DNA Replication R-HSA-69306
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of AXIN R-HSA-4641257
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Transition R-HSA-69275
Signaling by ROBO receptors R-HSA-376176
Cell Cycle, Mitotic R-HSA-69278
Assembly of the pre-replicative complex R-HSA-68867
Signal Transduction R-HSA-162582
PCP/CE pathway R-HSA-4086400
Regulation of RAS by GAPs R-HSA-5658442
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Programmed Cell Death R-HSA-5357801
Cellular response to hypoxia R-HSA-1234174
Apoptosis R-HSA-109581
Metabolism R-HSA-1430728
Hedgehog 'on' state R-HSA-5632684
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by NOTCH R-HSA-157118
ER-Phagosome pathway R-HSA-1236974
Host Interactions of HIV factors R-HSA-162909
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by Hedgehog R-HSA-5358351
G1/S DNA Damage Checkpoints R-HSA-69615
Mitotic Anaphase R-HSA-68882
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK1/MAPK3 signaling R-HSA-5684996
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cell Cycle Checkpoints R-HSA-69620
M Phase R-HSA-68886
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Gene expression (Transcription) R-HSA-74160
Neutrophil degranulation R-HSA-6798695
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX1 R-HSA-8878171
G1/S Transition R-HSA-69206
Class I MHC mediated antigen processing & presentation R-HSA-983169
RNA Polymerase II Transcription R-HSA-73857
MAPK6/MAPK4 signaling R-HSA-5687128
Negative regulation of NOTCH4 signaling R-HSA-9604323
Transcriptional regulation by RUNX3 R-HSA-8878159
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by Interleukins R-HSA-449147
Degradation of DVL R-HSA-4641258
Vpu mediated degradation of CD4 R-HSA-180534
Apoptosis R-HSA-109581
Metabolism R-HSA-1430728
DNA Replication R-HSA-69306
Post-translational protein modification R-HSA-597592
TCF dependent signaling in response to WNT R-HSA-201681
Vpu mediated degradation of CD4 R-HSA-180534
ABC-family proteins mediated transport R-HSA-382556
Axon guidance R-HSA-422475
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Programmed Cell Death R-HSA-5357801
Asymmetric localization of PCP proteins R-HSA-4608870
Disease R-HSA-1643685
KEAP1-NFE2L2 pathway R-HSA-9755511
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
MAPK6/MAPK4 signaling R-HSA-5687128
Deubiquitination R-HSA-5688426
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Negative regulation of NOTCH4 signaling R-HSA-9604323
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Infectious disease R-HSA-5663205
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RUNX2 expression and activity R-HSA-8939902
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stress R-HSA-2262752
Vif-mediated degradation of APOBEC3G R-HSA-180585
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by WNT R-HSA-195721
p53-Dependent G1 DNA Damage Response R-HSA-69563
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G2/M Transition R-HSA-69275
Metabolism of RNA R-HSA-8953854
CLEC7A (Dectin-1) signaling R-HSA-5607764
G1/S DNA Damage Checkpoints R-HSA-69615
ABC transporter disorders R-HSA-5619084
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
Stabilization of p53 R-HSA-69541
MAPK1/MAPK3 signaling R-HSA-5684996
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Generic Transcription Pathway R-HSA-212436
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of PTEN stability and activity R-HSA-8948751
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Adaptive Immune System R-HSA-1280218
Regulation of RUNX3 expression and activity R-HSA-8941858
Cellular responses to stimuli R-HSA-8953897
Neutrophil degranulation R-HSA-6798695
Metabolism of polyamines R-HSA-351202
Cellular response to chemical stress R-HSA-9711123
Mitotic Metaphase and Anaphase R-HSA-2555396
Hh mutants are degraded by ERAD R-HSA-5362768
Hedgehog 'off' state R-HSA-5610787
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
Developmental Biology R-HSA-1266738
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by ROBO receptors R-HSA-376176
Regulation of mitotic cell cycle R-HSA-453276
HIV Infection R-HSA-162906
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hedgehog ligand biogenesis R-HSA-5358346
Downstream TCR signaling R-HSA-202424
G1/S Transition R-HSA-69206
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX1 R-HSA-8878171
Cytokine Signaling in Immune system R-HSA-1280215
RAF/MAP kinase cascade R-HSA-5673001
Neddylation R-HSA-8951664
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hedgehog 'on' state R-HSA-5632684
Regulation of Apoptosis R-HSA-169911
Synthesis of DNA R-HSA-69239
TCR signaling R-HSA-202403
Metabolism of amino acids and derivatives R-HSA-71291
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Intracellular signaling by second messengers R-HSA-9006925
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G2-G2/M phases R-HSA-453274
Nervous system development R-HSA-9675108
Assembly of the pre-replicative complex R-HSA-68867
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to hypoxia R-HSA-1234174
UCH proteinases R-HSA-5689603
Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing-Cross presentation R-HSA-1236975
Regulation of expression of SLITs and ROBOs R-HSA-9010553
S Phase R-HSA-69242
Mitotic Anaphase R-HSA-68882
M Phase R-HSA-68886
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Host Interactions of HIV factors R-HSA-162909
p53-Independent DNA Damage Response R-HSA-69610
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
DNA Replication Pre-Initiation R-HSA-69002
Disorders of transmembrane transporters R-HSA-5619115
PCP/CE pathway R-HSA-4086400
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by Hedgehog R-HSA-5358351
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of AXIN R-HSA-4641257
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of DVL R-HSA-4641258
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transport of small molecules R-HSA-382551
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Switching of origins to a post-replicative state R-HSA-69052
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Separation of Sister Chromatids R-HSA-2467813
Cell Cycle, Mitotic R-HSA-69278
Degradation of GLI1 by the proteasome R-HSA-5610780
Interleukin-1 signaling R-HSA-9020702
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear events mediated by NFE2L2 R-HSA-9759194
Mitotic G1 phase and G1/S transition R-HSA-453279
FCERI mediated NF-kB activation R-HSA-2871837
Immune System R-HSA-168256
Transcriptional regulation by RUNX3 R-HSA-8878159
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cell Cycle Checkpoints R-HSA-69620
Signaling by NOTCH4 R-HSA-9013694
Interleukin-1 family signaling R-HSA-446652
Signaling by NOTCH R-HSA-157118
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ub-specific processing proteases R-HSA-5689880
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Orc1 removal from chromatin R-HSA-68949
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Deubiquitination R-HSA-5688426
RAF/MAP kinase cascade R-HSA-5673001
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Orc1 removal from chromatin R-HSA-68949
G2/M Checkpoints R-HSA-69481
Separation of Sister Chromatids R-HSA-2467813
C-type lectin receptors (CLRs) R-HSA-5621481
S Phase R-HSA-69242
Degradation of GLI1 by the proteasome R-HSA-5610780
Switching of origins to a post-replicative state R-HSA-69052
Synthesis of DNA R-HSA-69239
DNA Replication Pre-Initiation R-HSA-69002
PCP/CE pathway R-HSA-4086400
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Negative regulation of NOTCH4 signaling R-HSA-9604323
Adaptive Immune System R-HSA-1280218
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of amino acids and derivatives R-HSA-71291
MAPK6/MAPK4 signaling R-HSA-5687128
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Developmental Biology R-HSA-1266738
Signaling by Hedgehog R-HSA-5358351
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular responses to stimuli R-HSA-8953897
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic G2-G2/M phases R-HSA-453274
Signaling by Interleukins R-HSA-449147
Cellular response to chemical stress R-HSA-9711123
HIV Infection R-HSA-162906
TCR signaling R-HSA-202403
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cell Cycle R-HSA-1640170
Signaling by WNT R-HSA-195721
p53-Dependent G1 DNA Damage Response R-HSA-69563
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of proteins R-HSA-392499
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Stabilization of p53 R-HSA-69541
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing-Cross presentation R-HSA-1236975
Regulation of Apoptosis R-HSA-169911
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of RAS by GAPs R-HSA-5658442
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transcriptional regulation by RUNX2 R-HSA-8878166
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Immune System R-HSA-168256
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Vpu mediated degradation of CD4 R-HSA-180534
Vif-mediated degradation of APOBEC3G R-HSA-180585
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic Metaphase and Anaphase R-HSA-2555396
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transport of small molecules R-HSA-382551
Intracellular signaling by second messengers R-HSA-9006925
Nuclear events mediated by NFE2L2 R-HSA-9759194
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
DNA Replication R-HSA-69306
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic G1 phase and G1/S transition R-HSA-453279
Cellular responses to stress R-HSA-2262752
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Metabolism of polyamines R-HSA-351202
Neutrophil degranulation R-HSA-6798695
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ub-specific processing proteases R-HSA-5689880
Neddylation R-HSA-8951664
Cell Cycle Checkpoints R-HSA-69620
Mitotic Anaphase R-HSA-68882
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Programmed Cell Death R-HSA-5357801
Degradation of DVL R-HSA-4641258
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Gene expression (Transcription) R-HSA-74160
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Disease R-HSA-1643685
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Post-translational protein modification R-HSA-597592
Regulation of mitotic cell cycle R-HSA-453276
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of PTEN stability and activity R-HSA-8948751
Hedgehog 'on' state R-HSA-5632684
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
p53-Independent DNA Damage Response R-HSA-69610
Interleukin-1 signaling R-HSA-9020702
ER-Phagosome pathway R-HSA-1236974
Downstream TCR signaling R-HSA-202424
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
MAPK1/MAPK3 signaling R-HSA-5684996
Host Interactions of HIV factors R-HSA-162909
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
CLEC7A (Dectin-1) signaling R-HSA-5607764
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RUNX2 expression and activity R-HSA-8939902
M Phase R-HSA-68886
Signaling by NOTCH R-HSA-157118
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of beta-catenin by the destruction complex R-HSA-195253
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cell Cycle, Mitotic R-HSA-69278
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G1/S Transition R-HSA-69206
Signaling by ROBO receptors R-HSA-376176
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transcriptional regulation by RUNX1 R-HSA-8878171
ABC-family proteins mediated transport R-HSA-382556
G1/S DNA Damage Checkpoints R-HSA-69615
Infectious disease R-HSA-5663205
Hh mutants abrogate ligand secretion R-HSA-5387390
Generic Transcription Pathway R-HSA-212436
ABC transporter disorders R-HSA-5619084
TCF dependent signaling in response to WNT R-HSA-201681
Interleukin-1 family signaling R-HSA-446652
Defective CFTR causes cystic fibrosis R-HSA-5678895
UCH proteinases R-HSA-5689603
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog 'off' state R-HSA-5610787
Activation of NF-kappaB in B cells R-HSA-1169091
Transcriptional regulation by RUNX3 R-HSA-8878159
G2/M Transition R-HSA-69275
PTEN Regulation R-HSA-6807070
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Metabolism of RNA R-HSA-8953854
Degradation of GLI2 by the proteasome R-HSA-5610783
Apoptosis R-HSA-109581
Assembly of the pre-replicative complex R-HSA-68867
Degradation of AXIN R-HSA-4641257
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism R-HSA-1430728
Cellular response to hypoxia R-HSA-1234174
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
FCERI mediated NF-kB activation R-HSA-2871837
MAPK family signaling cascades R-HSA-5683057
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream TCR signaling R-HSA-202424
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Immune System R-HSA-168256
HIV Infection R-HSA-162906
CLEC7A (Dectin-1) signaling R-HSA-5607764
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by NOTCH R-HSA-157118
Interleukin-1 family signaling R-HSA-446652
Adaptive Immune System R-HSA-1280218
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Generic Transcription Pathway R-HSA-212436
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of Apoptosis R-HSA-169911
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PTEN Regulation R-HSA-6807070
Hh mutants are degraded by ERAD R-HSA-5362768
Separation of Sister Chromatids R-HSA-2467813
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog 'on' state R-HSA-5632684
Switching of origins to a post-replicative state R-HSA-69052
Synthesis of DNA R-HSA-69239
Regulation of RAS by GAPs R-HSA-5658442
Signaling by NOTCH4 R-HSA-9013694
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cyclin E associated events during G1/S transition R-HSA-69202
Gene expression (Transcription) R-HSA-74160
UCH proteinases R-HSA-5689603
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants abrogate ligand secretion R-HSA-5387390
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX1 R-HSA-8878171
Cell Cycle, Mitotic R-HSA-69278
Signaling by ROBO receptors R-HSA-376176
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Antigen processing-Cross presentation R-HSA-1236975
Degradation of AXIN R-HSA-4641257
Interleukin-1 signaling R-HSA-9020702
Post-translational protein modification R-HSA-597592
Nervous system development R-HSA-9675108
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cellular responses to stimuli R-HSA-8953897
G2/M Checkpoints R-HSA-69481
Nuclear events mediated by NFE2L2 R-HSA-9759194
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of mitotic cell cycle R-HSA-453276
Cell Cycle R-HSA-1640170
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX3 expression and activity R-HSA-8941858
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX3 R-HSA-8878159
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Defective CFTR causes cystic fibrosis R-HSA-5678895
Stabilization of p53 R-HSA-69541
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by Interleukins R-HSA-449147
ER-Phagosome pathway R-HSA-1236974
Regulation of RUNX2 expression and activity R-HSA-8939902
Hedgehog 'off' state R-HSA-5610787
Assembly of the pre-replicative complex R-HSA-68867
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
S Phase R-HSA-69242
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Vpu mediated degradation of CD4 R-HSA-180534
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G1/S Transition R-HSA-69206
G2/M Transition R-HSA-69275
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
RAF/MAP kinase cascade R-HSA-5673001
TCF dependent signaling in response to WNT R-HSA-201681
Transport of small molecules R-HSA-382551
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
PCP/CE pathway R-HSA-4086400
Metabolism of proteins R-HSA-392499
RNA Polymerase II Transcription R-HSA-73857
Cytokine Signaling in Immune system R-HSA-1280215
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of RNA R-HSA-8953854
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular responses to stress R-HSA-2262752
DNA Replication R-HSA-69306
ABC transporter disorders R-HSA-5619084
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PIP3 activates AKT signaling R-HSA-1257604
MAPK1/MAPK3 signaling R-HSA-5684996
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of polyamines R-HSA-351202
Degradation of beta-catenin by the destruction complex R-HSA-195253
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Neddylation R-HSA-8951664
p53-Dependent G1 DNA Damage Response R-HSA-69563
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
DNA Replication Pre-Initiation R-HSA-69002
Axon guidance R-HSA-422475
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Neutrophil degranulation R-HSA-6798695
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic G2-G2/M phases R-HSA-453274
Innate Immune System R-HSA-168249
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cell Cycle Checkpoints R-HSA-69620
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Ub-specific processing proteases R-HSA-5689880
KEAP1-NFE2L2 pathway R-HSA-9755511
Disorders of transmembrane transporters R-HSA-5619115
Vif-mediated degradation of APOBEC3G R-HSA-180585
Deubiquitination R-HSA-5688426
Hedgehog ligand biogenesis R-HSA-5358346
Orc1 removal from chromatin R-HSA-68949
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism R-HSA-1430728
Class I MHC mediated antigen processing & presentation R-HSA-983169
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular response to chemical stress R-HSA-9711123
Degradation of GLI2 by the proteasome R-HSA-5610783
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic Anaphase R-HSA-68882
C-type lectin receptors (CLRs) R-HSA-5621481
ABC-family proteins mediated transport R-HSA-382556
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
M Phase R-HSA-68886
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of DVL R-HSA-4641258
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to hypoxia R-HSA-1234174
TCR signaling R-HSA-202403
Programmed Cell Death R-HSA-5357801
Nervous system development R-HSA-9675108
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Neddylation R-HSA-8951664
Metabolism R-HSA-1430728
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hedgehog 'off' state R-HSA-5610787
Stabilization of p53 R-HSA-69541
Class I MHC mediated antigen processing & presentation R-HSA-983169
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Host Interactions of HIV factors R-HSA-162909
Metabolism of polyamines R-HSA-351202
Cellular responses to stimuli R-HSA-8953897
Adaptive Immune System R-HSA-1280218
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
HIV Infection R-HSA-162906
Degradation of DVL R-HSA-4641258
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by Hedgehog R-HSA-5358351
Immune System R-HSA-168256
Transcriptional regulation by RUNX1 R-HSA-8878171
ABC-family proteins mediated transport R-HSA-382556
Mitotic Anaphase R-HSA-68882
Cell Cycle R-HSA-1640170
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hedgehog 'on' state R-HSA-5632684
Cytokine Signaling in Immune system R-HSA-1280215
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
KEAP1-NFE2L2 pathway R-HSA-9755511
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
ER-Phagosome pathway R-HSA-1236974
Apoptosis R-HSA-109581
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Switching of origins to a post-replicative state R-HSA-69052
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
DNA Replication Pre-Initiation R-HSA-69002
Neutrophil degranulation R-HSA-6798695
Transport of small molecules R-HSA-382551
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular responses to stress R-HSA-2262752
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
M Phase R-HSA-68886
Assembly of the pre-replicative complex R-HSA-68867
G1/S Transition R-HSA-69206
Metabolism of amino acids and derivatives R-HSA-71291
FCERI mediated NF-kB activation R-HSA-2871837
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hh mutants are degraded by ERAD R-HSA-5362768
Deubiquitination R-HSA-5688426
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX2 R-HSA-8878166
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream TCR signaling R-HSA-202424
Cyclin E associated events during G1/S transition R-HSA-69202
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ub-specific processing proteases R-HSA-5689880
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of proteins R-HSA-392499
Gene expression (Transcription) R-HSA-74160
ABC transporter disorders R-HSA-5619084
PIP3 activates AKT signaling R-HSA-1257604
Infectious disease R-HSA-5663205
Signal Transduction R-HSA-162582
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog ligand biogenesis R-HSA-5358346
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of beta-catenin by the destruction complex R-HSA-195253
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hh mutants abrogate ligand secretion R-HSA-5387390
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by Interleukins R-HSA-449147
Orc1 removal from chromatin R-HSA-68949
G2/M Transition R-HSA-69275
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Mitotic G1 phase and G1/S transition R-HSA-453279
Intracellular signaling by second messengers R-HSA-9006925
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Separation of Sister Chromatids R-HSA-2467813
CLEC7A (Dectin-1) signaling R-HSA-5607764
PCP/CE pathway R-HSA-4086400
PTEN Regulation R-HSA-6807070
Interleukin-1 family signaling R-HSA-446652
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
DNA Replication R-HSA-69306
G2/M Checkpoints R-HSA-69481
Cellular response to hypoxia R-HSA-1234174
Cell Cycle, Mitotic R-HSA-69278
Vif-mediated degradation of APOBEC3G R-HSA-180585
Disorders of transmembrane transporters R-HSA-5619115
Cellular response to chemical stress R-HSA-9711123
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of Apoptosis R-HSA-169911
p53-Independent DNA Damage Response R-HSA-69610
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Degradation of GLI2 by the proteasome R-HSA-5610783
Defective CFTR causes cystic fibrosis R-HSA-5678895
S Phase R-HSA-69242
Regulation of RUNX2 expression and activity R-HSA-8939902
Asymmetric localization of PCP proteins R-HSA-4608870
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of GLI1 by the proteasome R-HSA-5610780
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of AXIN R-HSA-4641257
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by ROBO receptors R-HSA-376176
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
RNA Polymerase II Transcription R-HSA-73857
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1 DNA Damage Response R-HSA-69563
Interleukin-1 signaling R-HSA-9020702
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RAS by GAPs R-HSA-5658442
Signaling by WNT R-HSA-195721
Post-translational protein modification R-HSA-597592
Disease R-HSA-1643685
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cell Cycle Checkpoints R-HSA-69620
Negative regulation of NOTCH4 signaling R-HSA-9604323
Synthesis of DNA R-HSA-69239
Metabolism of RNA R-HSA-8953854
TCR signaling R-HSA-202403
UCH proteinases R-HSA-5689603
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH R-HSA-157118
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX3 R-HSA-8878159
Innate Immune System R-HSA-168249
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
MAPK1/MAPK3 signaling R-HSA-5684996
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Gene expression (Transcription) R-HSA-74160
Cellular response to hypoxia R-HSA-1234174
Developmental Biology R-HSA-1266738
Vpu mediated degradation of CD4 R-HSA-180534
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism of proteins R-HSA-392499
Antigen processing-Cross presentation R-HSA-1236975
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Neutrophil degranulation R-HSA-6798695
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Neddylation R-HSA-8951664
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S DNA Damage Checkpoints R-HSA-69615
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Transcriptional regulation by RUNX2 R-HSA-8878166
Ub-specific processing proteases R-HSA-5689880
NIK-->noncanonical NF-kB signaling R-HSA-5676590
RAF/MAP kinase cascade R-HSA-5673001
Transcriptional regulation by RUNX3 R-HSA-8878159
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
KEAP1-NFE2L2 pathway R-HSA-9755511
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Degradation of DVL R-HSA-4641258
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Negative regulation of NOTCH4 signaling R-HSA-9604323
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
S Phase R-HSA-69242
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1 DNA Damage Response R-HSA-69563
ER-Phagosome pathway R-HSA-1236974
Mitotic G2-G2/M phases R-HSA-453274
MAPK6/MAPK4 signaling R-HSA-5687128
G2/M Checkpoints R-HSA-69481
Regulation of mitotic cell cycle R-HSA-453276
Degradation of GLI2 by the proteasome R-HSA-5610783
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
PTEN Regulation R-HSA-6807070
Immune System R-HSA-168256
Cell Cycle R-HSA-1640170
DNA Replication Pre-Initiation R-HSA-69002
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK1/MAPK3 signaling R-HSA-5684996
Transport of small molecules R-HSA-382551
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Infectious disease R-HSA-5663205
Mitotic G1 phase and G1/S transition R-HSA-453279
ABC-family proteins mediated transport R-HSA-382556
Nuclear events mediated by NFE2L2 R-HSA-9759194
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RUNX3 expression and activity R-HSA-8941858
Orc1 removal from chromatin R-HSA-68949
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Class I MHC mediated antigen processing & presentation R-HSA-983169
PCP/CE pathway R-HSA-4086400
Beta-catenin independent WNT signaling R-HSA-3858494
Axon guidance R-HSA-422475
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants are degraded by ERAD R-HSA-5362768
UCH proteinases R-HSA-5689603
Hh mutants abrogate ligand secretion R-HSA-5387390
Cyclin E associated events during G1/S transition R-HSA-69202
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of RAS by GAPs R-HSA-5658442
Adaptive Immune System R-HSA-1280218
DNA Replication R-HSA-69306
Metabolism of amino acids and derivatives R-HSA-71291
Cellular response to chemical stress R-HSA-9711123
M Phase R-HSA-68886
Mitotic Anaphase R-HSA-68882
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Switching of origins to a post-replicative state R-HSA-69052
Apoptosis R-HSA-109581
Metabolism of RNA R-HSA-8953854
FCERI mediated NF-kB activation R-HSA-2871837
Nervous system development R-HSA-9675108
Asymmetric localization of PCP proteins R-HSA-4608870
HIV Infection R-HSA-162906
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
Cytokine Signaling in Immune system R-HSA-1280215
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Synthesis of DNA R-HSA-69239
Activation of NF-kappaB in B cells R-HSA-1169091
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Disorders of transmembrane transporters R-HSA-5619115
Post-translational protein modification R-HSA-597592
Cellular responses to stress R-HSA-2262752
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by WNT R-HSA-195721
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by NOTCH4 R-HSA-9013694
Metabolism R-HSA-1430728
Assembly of the pre-replicative complex R-HSA-68867
Hedgehog 'off' state R-HSA-5610787
Regulation of Apoptosis R-HSA-169911
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Stabilization of p53 R-HSA-69541
MAPK family signaling cascades R-HSA-5683057
Signaling by Hedgehog R-HSA-5358351
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hedgehog 'on' state R-HSA-5632684
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Disease R-HSA-1643685
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Intracellular signaling by second messengers R-HSA-9006925
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Transition R-HSA-69275
Cell Cycle, Mitotic R-HSA-69278
Signaling by ROBO receptors R-HSA-376176
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 family signaling R-HSA-446652
G1/S Transition R-HSA-69206
Generic Transcription Pathway R-HSA-212436
Metabolism of polyamines R-HSA-351202
Signaling by Interleukins R-HSA-449147
Downstream TCR signaling R-HSA-202424
TCR signaling R-HSA-202403
Deubiquitination R-HSA-5688426
Interleukin-1 signaling R-HSA-9020702
Separation of Sister Chromatids R-HSA-2467813
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of AXIN R-HSA-4641257
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell Cycle Checkpoints R-HSA-69620
Host Interactions of HIV factors R-HSA-162909
Innate Immune System R-HSA-168249
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Independent DNA Damage Response R-HSA-69610
TCF dependent signaling in response to WNT R-HSA-201681
Innate Immune System R-HSA-168249
Mitotic G1 phase and G1/S transition R-HSA-453279
Infectious disease R-HSA-5663205
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle, Mitotic R-HSA-69278
Deubiquitination R-HSA-5688426
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of RNA R-HSA-8953854
Cellular response to chemical stress R-HSA-9711123
Switching of origins to a post-replicative state R-HSA-69052
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Neddylation R-HSA-8951664
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of beta-catenin by the destruction complex R-HSA-195253
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants abrogate ligand secretion R-HSA-5387390
Generic Transcription Pathway R-HSA-212436
Asymmetric localization of PCP proteins R-HSA-4608870
p53-Dependent G1 DNA Damage Response R-HSA-69563
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transport of small molecules R-HSA-382551
Metabolism of polyamines R-HSA-351202
S Phase R-HSA-69242
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog 'off' state R-HSA-5610787
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by ROBO receptors R-HSA-376176
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Independent DNA Damage Response R-HSA-69610
Disorders of transmembrane transporters R-HSA-5619115
TCR signaling R-HSA-202403
Beta-catenin independent WNT signaling R-HSA-3858494
FCERI mediated NF-kB activation R-HSA-2871837
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cell Cycle Checkpoints R-HSA-69620
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Disease R-HSA-1643685
G2/M Transition R-HSA-69275
G2/M Checkpoints R-HSA-69481
Antigen processing-Cross presentation R-HSA-1236975
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Adaptive Immune System R-HSA-1280218
Host Interactions of HIV factors R-HSA-162909
Regulation of RUNX2 expression and activity R-HSA-8939902
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
DNA Replication R-HSA-69306
Immune System R-HSA-168256
Hedgehog 'on' state R-HSA-5632684
Metabolism R-HSA-1430728
Cellular responses to stress R-HSA-2262752
ABC transporter disorders R-HSA-5619084
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX3 R-HSA-8878159
Vpu mediated degradation of CD4 R-HSA-180534
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX1 R-HSA-8878171
UCH proteinases R-HSA-5689603
Signaling by Interleukins R-HSA-449147
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX2 R-HSA-8878166
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hh mutants are degraded by ERAD R-HSA-5362768
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK family signaling cascades R-HSA-5683057
Cell Cycle R-HSA-1640170
Metabolism of amino acids and derivatives R-HSA-71291
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
MAPK1/MAPK3 signaling R-HSA-5684996
Separation of Sister Chromatids R-HSA-2467813
Interleukin-1 signaling R-HSA-9020702
Post-translational protein modification R-HSA-597592
HIV Infection R-HSA-162906
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Nervous system development R-HSA-9675108
Apoptosis R-HSA-109581
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Neutrophil degranulation R-HSA-6798695
Degradation of GLI1 by the proteasome R-HSA-5610780
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH4 R-HSA-9013694
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Synthesis of DNA R-HSA-69239
Metabolism of proteins R-HSA-392499
Degradation of DVL R-HSA-4641258
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by Hedgehog R-HSA-5358351
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Assembly of the pre-replicative complex R-HSA-68867
Programmed Cell Death R-HSA-5357801
Signal Transduction R-HSA-162582
DNA Replication Pre-Initiation R-HSA-69002
Signaling by NOTCH R-HSA-157118
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of GLI2 by the proteasome R-HSA-5610783
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Intracellular signaling by second messengers R-HSA-9006925
Class I MHC mediated antigen processing & presentation R-HSA-983169
Activation of NF-kappaB in B cells R-HSA-1169091
Ub-specific processing proteases R-HSA-5689880
RNA Polymerase II Transcription R-HSA-73857
Axon guidance R-HSA-422475
G1/S DNA Damage Checkpoints R-HSA-69615
PTEN Regulation R-HSA-6807070
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular responses to stimuli R-HSA-8953897
Negative regulation of NOTCH4 signaling R-HSA-9604323
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
M Phase R-HSA-68886
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of mitotic cell cycle R-HSA-453276
Orc1 removal from chromatin R-HSA-68949
Interleukin-1 family signaling R-HSA-446652
Downstream TCR signaling R-HSA-202424
ABC-family proteins mediated transport R-HSA-382556
Regulation of Apoptosis R-HSA-169911
Developmental Biology R-HSA-1266738
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G2-G2/M phases R-HSA-453274
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
RAF/MAP kinase cascade R-HSA-5673001
G1/S Transition R-HSA-69206
Degradation of AXIN R-HSA-4641257
Hedgehog ligand biogenesis R-HSA-5358346
Stabilization of p53 R-HSA-69541
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by WNT R-HSA-195721
PCP/CE pathway R-HSA-4086400
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of PTEN stability and activity R-HSA-8948751
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of RAS by GAPs R-HSA-5658442
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI1 by the proteasome R-HSA-5610780
Nervous system development R-HSA-9675108
Neddylation R-HSA-8951664
Degradation of DVL R-HSA-4641258
Synthesis of DNA R-HSA-69239
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Class I MHC mediated antigen processing & presentation R-HSA-983169
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signaling by Hedgehog R-HSA-5358351
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Disease R-HSA-1643685
Degradation of AXIN R-HSA-4641257
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Dependent G1 DNA Damage Response R-HSA-69563
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
NIK-->noncanonical NF-kB signaling R-HSA-5676590
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of RNA R-HSA-8953854
Interleukin-1 family signaling R-HSA-446652
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Interleukin-1 signaling R-HSA-9020702
Mitotic G1 phase and G1/S transition R-HSA-453279
Disorders of transmembrane transporters R-HSA-5619115
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Developmental Biology R-HSA-1266738
Intracellular signaling by second messengers R-HSA-9006925
ABC-family proteins mediated transport R-HSA-382556
Mitotic Anaphase R-HSA-68882
RAF/MAP kinase cascade R-HSA-5673001
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PTEN Regulation R-HSA-6807070
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication R-HSA-69306
Metabolism of polyamines R-HSA-351202
TCR signaling R-HSA-202403
Cellular response to hypoxia R-HSA-1234174
Signaling by WNT R-HSA-195721
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Vpu mediated degradation of CD4 R-HSA-180534
Innate Immune System R-HSA-168249
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Defective CFTR causes cystic fibrosis R-HSA-5678895
Axon guidance R-HSA-422475
Hh mutants are degraded by ERAD R-HSA-5362768
S Phase R-HSA-69242
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'off' state R-HSA-5610787
PCP/CE pathway R-HSA-4086400
Ub-specific processing proteases R-HSA-5689880
G1/S DNA Damage Checkpoints R-HSA-69615
Post-translational protein modification R-HSA-597592
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Assembly of the pre-replicative complex R-HSA-68867
G2/M Checkpoints R-HSA-69481
M Phase R-HSA-68886
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX3 R-HSA-8878159
C-type lectin receptors (CLRs) R-HSA-5621481
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of proteins R-HSA-392499
Adaptive Immune System R-HSA-1280218
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog ligand biogenesis R-HSA-5358346
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
TCF dependent signaling in response to WNT R-HSA-201681
Hh mutants abrogate ligand secretion R-HSA-5387390
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism R-HSA-1430728
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream TCR signaling R-HSA-202424
Cellular responses to stress R-HSA-2262752
G2/M Transition R-HSA-69275
PIP3 activates AKT signaling R-HSA-1257604
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle Checkpoints R-HSA-69620
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Vif-mediated degradation of APOBEC3G R-HSA-180585
Separation of Sister Chromatids R-HSA-2467813
Programmed Cell Death R-HSA-5357801
Asymmetric localization of PCP proteins R-HSA-4608870
Stabilization of p53 R-HSA-69541
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Infectious disease R-HSA-5663205
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of Apoptosis R-HSA-169911
UCH proteinases R-HSA-5689603
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
ABC transporter disorders R-HSA-5619084
Generic Transcription Pathway R-HSA-212436
Apoptosis R-HSA-109581
Neutrophil degranulation R-HSA-6798695
Cellular responses to stimuli R-HSA-8953897
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
HIV Infection R-HSA-162906
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Independent DNA Damage Response R-HSA-69610
Cell Cycle, Mitotic R-HSA-69278
Beta-catenin independent WNT signaling R-HSA-3858494
DNA Replication Pre-Initiation R-HSA-69002
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by NOTCH4 R-HSA-9013694
Gene expression (Transcription) R-HSA-74160
Deubiquitination R-HSA-5688426
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
RNA Polymerase II Transcription R-HSA-73857
Transport of small molecules R-HSA-382551
Activation of NF-kappaB in B cells R-HSA-1169091
Orc1 removal from chromatin R-HSA-68949
Cell Cycle R-HSA-1640170
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of mitotic cell cycle R-HSA-453276
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by ROBO receptors R-HSA-376176
ER-Phagosome pathway R-HSA-1236974
Signaling by Interleukins R-HSA-449147
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Immune System R-HSA-168256
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of GLI2 by the proteasome R-HSA-5610783
G1/S Transition R-HSA-69206
Signaling by NOTCH R-HSA-157118
Cellular response to chemical stress R-HSA-9711123
Signal Transduction R-HSA-162582
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hedgehog 'on' state R-HSA-5632684
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Switching of origins to a post-replicative state R-HSA-69052
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of amino acids and derivatives R-HSA-71291
Host Interactions of HIV factors R-HSA-162909
HIV Infection R-HSA-162906
PCP/CE pathway R-HSA-4086400
Separation of Sister Chromatids R-HSA-2467813
Neddylation R-HSA-8951664
Signaling by NOTCH4 R-HSA-9013694
Vpu mediated degradation of CD4 R-HSA-180534
RNA Polymerase II Transcription R-HSA-73857
Programmed Cell Death R-HSA-5357801
Regulation of expression of SLITs and ROBOs R-HSA-9010553
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK1/MAPK3 signaling R-HSA-5684996
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Hedgehog R-HSA-5358351
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'off' state R-HSA-5610787
Stabilization of p53 R-HSA-69541
Cellular response to chemical stress R-HSA-9711123
TCR signaling R-HSA-202403
Downstream TCR signaling R-HSA-202424
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-1 signaling R-HSA-9020702
UCH proteinases R-HSA-5689603
Orc1 removal from chromatin R-HSA-68949
Ub-specific processing proteases R-HSA-5689880
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Hedgehog ligand biogenesis R-HSA-5358346
p53-Independent DNA Damage Response R-HSA-69610
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic G2-G2/M phases R-HSA-453274
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Deubiquitination R-HSA-5688426
Post-translational protein modification R-HSA-597592
Hh mutants abrogate ligand secretion R-HSA-5387390
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of AXIN R-HSA-4641257
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
Regulation of Apoptosis R-HSA-169911
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Apoptosis R-HSA-109581
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX3 R-HSA-8878159
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of mitotic cell cycle R-HSA-453276
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Vif-mediated degradation of APOBEC3G R-HSA-180585
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of GLI2 by the proteasome R-HSA-5610783
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Degradation of DVL R-HSA-4641258
ER-Phagosome pathway R-HSA-1236974
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Synthesis of DNA R-HSA-69239
DNA Replication R-HSA-69306
Regulation of RUNX3 expression and activity R-HSA-8941858
Beta-catenin independent WNT signaling R-HSA-3858494
Signal Transduction R-HSA-162582
Metabolism of polyamines R-HSA-351202
Neutrophil degranulation R-HSA-6798695
Asymmetric localization of PCP proteins R-HSA-4608870
Generic Transcription Pathway R-HSA-212436
G2/M Transition R-HSA-69275
Regulation of RAS by GAPs R-HSA-5658442
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by ROBO receptors R-HSA-376176
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH R-HSA-157118
Disorders of transmembrane transporters R-HSA-5619115
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cellular responses to stimuli R-HSA-8953897
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 family signaling R-HSA-446652
RAF/MAP kinase cascade R-HSA-5673001
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Immune System R-HSA-168256
Antigen processing-Cross presentation R-HSA-1236975
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G1/S DNA Damage Checkpoints R-HSA-69615
ABC-family proteins mediated transport R-HSA-382556
Transport of small molecules R-HSA-382551
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
Cellular response to hypoxia R-HSA-1234174
Signaling by WNT R-HSA-195721
Assembly of the pre-replicative complex R-HSA-68867
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metabolism of RNA R-HSA-8953854
PTEN Regulation R-HSA-6807070
p53-Dependent G1 DNA Damage Response R-HSA-69563
Host Interactions of HIV factors R-HSA-162909
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of NF-kappaB in B cells R-HSA-1169091
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism R-HSA-1430728
G1/S Transition R-HSA-69206
M Phase R-HSA-68886
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of beta-catenin by the destruction complex R-HSA-195253
Switching of origins to a post-replicative state R-HSA-69052
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Class I MHC mediated antigen processing & presentation R-HSA-983169
Adaptive Immune System R-HSA-1280218
Transcriptional regulation by RUNX1 R-HSA-8878171
ABC transporter disorders R-HSA-5619084
Cellular responses to stress R-HSA-2262752
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle, Mitotic R-HSA-69278
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of PTEN stability and activity R-HSA-8948751
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of GLI1 by the proteasome R-HSA-5610780
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic Metaphase and Anaphase R-HSA-2555396
Cytokine Signaling in Immune system R-HSA-1280215
Defective CFTR causes cystic fibrosis R-HSA-5678895
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of amino acids and derivatives R-HSA-71291
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism of proteins R-HSA-392499
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cyclin E associated events during G1/S transition R-HSA-69202
PIP3 activates AKT signaling R-HSA-1257604
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog 'on' state R-HSA-5632684
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX2 expression and activity R-HSA-8939902
Axon guidance R-HSA-422475
G2/M Checkpoints R-HSA-69481
Signaling by Interleukins R-HSA-449147
TCF dependent signaling in response to WNT R-HSA-201681
Cell Cycle R-HSA-1640170
S Phase R-HSA-69242
MAPK family signaling cascades R-HSA-5683057

Expression Atlas ENSG00000106588
NCBI gene (formerly Entrezgene) 5683
GeneCards 9531
HGNC Symbol HGNC:9531
MIM gene 176842
UniProtKB Gene Name P25787
WikiGene 5683
Gene: PSMB8
Ensembl ID : ENSG00000204264
Description: proteasome 20S subunit beta 8
Gene Synonyms: BETA5I,D6S216E,LMP7,PSMB5I,RING10
6 APIs:
221 Possible Orthologues:

Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Synthesis of DNA R-HSA-69239
Ub-specific processing proteases R-HSA-5689880
ABC transporter disorders R-HSA-5619084
Post-translational protein modification R-HSA-597592
ABC-family proteins mediated transport R-HSA-382556
Programmed Cell Death R-HSA-5357801
FCERI mediated NF-kB activation R-HSA-2871837
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Nervous system development R-HSA-9675108
Switching of origins to a post-replicative state R-HSA-69052
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of beta-catenin by the destruction complex R-HSA-195253
Gene expression (Transcription) R-HSA-74160
G2/M Transition R-HSA-69275
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
KEAP1-NFE2L2 pathway R-HSA-9755511
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Interleukin-1 family signaling R-HSA-446652
Regulation of Apoptosis R-HSA-169911
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
MAPK family signaling cascades R-HSA-5683057
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Metabolism of amino acids and derivatives R-HSA-71291
MAPK1/MAPK3 signaling R-HSA-5684996
S Phase R-HSA-69242
Vif-mediated degradation of APOBEC3G R-HSA-180585
Hedgehog ligand biogenesis R-HSA-5358346
Developmental Biology R-HSA-1266738
Orc1 removal from chromatin R-HSA-68949
Stabilization of p53 R-HSA-69541
Metabolism R-HSA-1430728
Hedgehog 'on' state R-HSA-5632684
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by NOTCH4 R-HSA-9013694
Cell Cycle R-HSA-1640170
Cytokine Signaling in Immune system R-HSA-1280215
PTEN Regulation R-HSA-6807070
RAF/MAP kinase cascade R-HSA-5673001
HIV Infection R-HSA-162906
TCF dependent signaling in response to WNT R-HSA-201681
Interleukin-1 signaling R-HSA-9020702
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX3 R-HSA-8878159
G1/S DNA Damage Checkpoints R-HSA-69615
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cellular response to chemical stress R-HSA-9711123
Regulation of RAS by GAPs R-HSA-5658442
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of GLI1 by the proteasome R-HSA-5610780
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by WNT R-HSA-195721
C-type lectin receptors (CLRs) R-HSA-5621481
Mitotic Metaphase and Anaphase R-HSA-2555396
CLEC7A (Dectin-1) signaling R-HSA-5607764
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH R-HSA-157118
Immune System R-HSA-168256
Beta-catenin independent WNT signaling R-HSA-3858494
G1/S Transition R-HSA-69206
Degradation of DVL R-HSA-4641258
Metabolism of proteins R-HSA-392499
Mitotic G1 phase and G1/S transition R-HSA-453279
ER-Phagosome pathway R-HSA-1236974
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Intracellular signaling by second messengers R-HSA-9006925
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of mitotic cell cycle R-HSA-453276
Transcriptional regulation by RUNX2 R-HSA-8878166
Infectious disease R-HSA-5663205
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing-Cross presentation R-HSA-1236975
Signaling by Interleukins R-HSA-449147
Interferon alpha/beta signaling R-HSA-909733
PIP3 activates AKT signaling R-HSA-1257604
UCH proteinases R-HSA-5689603
Cell Cycle Checkpoints R-HSA-69620
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Disorders of transmembrane transporters R-HSA-5619115
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
Axon guidance R-HSA-422475
Apoptosis R-HSA-109581
Vpu mediated degradation of CD4 R-HSA-180534
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of polyamines R-HSA-351202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cell Cycle, Mitotic R-HSA-69278
Signal Transduction R-HSA-162582
Negative regulation of NOTCH4 signaling R-HSA-9604323
Neddylation R-HSA-8951664
DNA Replication R-HSA-69306
TCR signaling R-HSA-202403
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
p53-Independent DNA Damage Response R-HSA-69610
Interferon Signaling R-HSA-913531
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular responses to stimuli R-HSA-8953897
Signaling by Hedgehog R-HSA-5358351
Metabolism of RNA R-HSA-8953854
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Host Interactions of HIV factors R-HSA-162909
Separation of Sister Chromatids R-HSA-2467813
Adaptive Immune System R-HSA-1280218
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX2 expression and activity R-HSA-8939902
PCP/CE pathway R-HSA-4086400
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Transport of small molecules R-HSA-382551
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Assembly of the pre-replicative complex R-HSA-68867
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Mitotic G2-G2/M phases R-HSA-453274
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Defective CFTR causes cystic fibrosis R-HSA-5678895
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Innate Immune System R-HSA-168249
Deubiquitination R-HSA-5688426
Disease R-HSA-1643685
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of PTEN stability and activity R-HSA-8948751
M Phase R-HSA-68886
Degradation of AXIN R-HSA-4641257
Signaling by ROBO receptors R-HSA-376176
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic Anaphase R-HSA-68882
Downstream TCR signaling R-HSA-202424
Hh mutants abrogate ligand secretion R-HSA-5387390
DNA Replication Pre-Initiation R-HSA-69002
Regulation of RUNX3 expression and activity R-HSA-8941858
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Transcriptional regulation by RUNX1 R-HSA-8878171
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Nervous system development R-HSA-9675108
M Phase R-HSA-68886
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Metabolism R-HSA-1430728
Interleukin-1 signaling R-HSA-9020702
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of GLI1 by the proteasome R-HSA-5610780
Signal Transduction R-HSA-162582
Cellular responses to stress R-HSA-2262752
Cyclin E associated events during G1/S transition R-HSA-69202
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Apoptosis R-HSA-109581
Post-translational protein modification R-HSA-597592
Metabolism of RNA R-HSA-8953854
Vpu mediated degradation of CD4 R-HSA-180534
Neddylation R-HSA-8951664
Metabolism of amino acids and derivatives R-HSA-71291
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular response to chemical stress R-HSA-9711123
Mitotic G2-G2/M phases R-HSA-453274
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mitotic cell cycle R-HSA-453276
Signaling by Hedgehog R-HSA-5358351
G2/M Transition R-HSA-69275
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hedgehog ligand biogenesis R-HSA-5358346
Interferon Signaling R-HSA-913531
Generic Transcription Pathway R-HSA-212436
Interferon alpha/beta signaling R-HSA-909733
Stabilization of p53 R-HSA-69541
Orc1 removal from chromatin R-HSA-68949
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Asymmetric localization of PCP proteins R-HSA-4608870
HIV Infection R-HSA-162906
Signaling by WNT R-HSA-195721
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by NOTCH4 R-HSA-9013694
ABC-family proteins mediated transport R-HSA-382556
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic Anaphase R-HSA-68882
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Host Interactions of HIV factors R-HSA-162909
Metabolism of polyamines R-HSA-351202
Regulation of PTEN stability and activity R-HSA-8948751
S Phase R-HSA-69242
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by Interleukins R-HSA-449147
Class I MHC mediated antigen processing & presentation R-HSA-983169
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by ROBO receptors R-HSA-376176
Intracellular signaling by second messengers R-HSA-9006925
Degradation of GLI2 by the proteasome R-HSA-5610783
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of Apoptosis R-HSA-169911
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
FCERI mediated NF-kB activation R-HSA-2871837
Assembly of the pre-replicative complex R-HSA-68867
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK1/MAPK3 signaling R-HSA-5684996
Developmental Biology R-HSA-1266738
Regulation of RUNX2 expression and activity R-HSA-8939902
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
TCR signaling R-HSA-202403
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Disease R-HSA-1643685
TCF dependent signaling in response to WNT R-HSA-201681
PIP3 activates AKT signaling R-HSA-1257604
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Disorders of transmembrane transporters R-HSA-5619115
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
UCH proteinases R-HSA-5689603
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
RAF/MAP kinase cascade R-HSA-5673001
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hedgehog 'on' state R-HSA-5632684
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G2/M Checkpoints R-HSA-69481
Degradation of beta-catenin by the destruction complex R-HSA-195253
G1/S Transition R-HSA-69206
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Deubiquitination R-HSA-5688426
Infectious disease R-HSA-5663205
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
CLEC7A (Dectin-1) signaling R-HSA-5607764
DNA Replication R-HSA-69306
Degradation of AXIN R-HSA-4641257
Regulation of RUNX3 expression and activity R-HSA-8941858
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by NOTCH R-HSA-157118
Separation of Sister Chromatids R-HSA-2467813
p53-Independent DNA Damage Response R-HSA-69610
Ub-specific processing proteases R-HSA-5689880
Degradation of DVL R-HSA-4641258
Axon guidance R-HSA-422475
Cellular response to hypoxia R-HSA-1234174
PCP/CE pathway R-HSA-4086400
Hh mutants are degraded by ERAD R-HSA-5362768
C-type lectin receptors (CLRs) R-HSA-5621481
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Synthesis of DNA R-HSA-69239
PTEN Regulation R-HSA-6807070
RNA Polymerase II Transcription R-HSA-73857
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Antigen processing-Cross presentation R-HSA-1236975
Innate Immune System R-HSA-168249
Cellular responses to stimuli R-HSA-8953897
Regulation of RAS by GAPs R-HSA-5658442
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
ABC transporter disorders R-HSA-5619084
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Metaphase and Anaphase R-HSA-2555396
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 family signaling R-HSA-446652
Programmed Cell Death R-HSA-5357801
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Nuclear events mediated by NFE2L2 R-HSA-9759194
ER-Phagosome pathway R-HSA-1236974
p53-Dependent G1 DNA Damage Response R-HSA-69563
Immune System R-HSA-168256
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Gene expression (Transcription) R-HSA-74160
MAPK family signaling cascades R-HSA-5683057
Transport of small molecules R-HSA-382551
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hedgehog 'off' state R-HSA-5610787
Beta-catenin independent WNT signaling R-HSA-3858494
Cytokine Signaling in Immune system R-HSA-1280215
Adaptive Immune System R-HSA-1280218
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX3 R-HSA-8878159
Cell Cycle, Mitotic R-HSA-69278
DNA Replication Pre-Initiation R-HSA-69002
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of proteins R-HSA-392499
Switching of origins to a post-replicative state R-HSA-69052
Downstream TCR signaling R-HSA-202424
Activation of NF-kappaB in B cells R-HSA-1169091
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Hh mutants are degraded by ERAD R-HSA-5362768
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Gene expression (Transcription) R-HSA-74160
Apoptosis R-HSA-109581
Regulation of RUNX2 expression and activity R-HSA-8939902
DNA Replication R-HSA-69306
Signaling by NOTCH4 R-HSA-9013694
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
PIP3 activates AKT signaling R-HSA-1257604
G2/M Transition R-HSA-69275
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Disorders of transmembrane transporters R-HSA-5619115
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Ub-specific processing proteases R-HSA-5689880
Regulation of Apoptosis R-HSA-169911
UCH proteinases R-HSA-5689603
Transport of small molecules R-HSA-382551
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Synthesis of DNA R-HSA-69239
Activation of NF-kappaB in B cells R-HSA-1169091
Assembly of the pre-replicative complex R-HSA-68867
Infectious disease R-HSA-5663205
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Host Interactions of HIV factors R-HSA-162909
ABC transporter disorders R-HSA-5619084
Interferon alpha/beta signaling R-HSA-909733
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Orc1 removal from chromatin R-HSA-68949
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Interleukins R-HSA-449147
Generic Transcription Pathway R-HSA-212436
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of GLI2 by the proteasome R-HSA-5610783
Innate Immune System R-HSA-168249
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interferon Signaling R-HSA-913531
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic Anaphase R-HSA-68882
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular responses to stimuli R-HSA-8953897
Metabolism of proteins R-HSA-392499
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of NOTCH4 signaling R-HSA-9604323
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
DNA Replication Pre-Initiation R-HSA-69002
G1/S Transition R-HSA-69206
Developmental Biology R-HSA-1266738
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by ROBO receptors R-HSA-376176
S Phase R-HSA-69242
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX2 R-HSA-8878166
FCERI mediated NF-kB activation R-HSA-2871837
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Deubiquitination R-HSA-5688426
p53-Independent DNA Damage Response R-HSA-69610
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX3 R-HSA-8878159
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of GLI1 by the proteasome R-HSA-5610780
G2/M Checkpoints R-HSA-69481
ABC-family proteins mediated transport R-HSA-382556
Degradation of AXIN R-HSA-4641257
Neddylation R-HSA-8951664
Mitotic G1 phase and G1/S transition R-HSA-453279
TCR signaling R-HSA-202403
Hedgehog 'on' state R-HSA-5632684
ER-Phagosome pathway R-HSA-1236974
MAPK family signaling cascades R-HSA-5683057
TCF dependent signaling in response to WNT R-HSA-201681
Switching of origins to a post-replicative state R-HSA-69052
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular response to hypoxia R-HSA-1234174
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cell Cycle R-HSA-1640170
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular responses to stress R-HSA-2262752
Axon guidance R-HSA-422475
Metabolism of polyamines R-HSA-351202
Stabilization of p53 R-HSA-69541
Degradation of beta-catenin by the destruction complex R-HSA-195253
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of amino acids and derivatives R-HSA-71291
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by WNT R-HSA-195721
Interleukin-1 family signaling R-HSA-446652
Cell Cycle, Mitotic R-HSA-69278
Nervous system development R-HSA-9675108
Mitotic Metaphase and Anaphase R-HSA-2555396
Hedgehog ligand biogenesis R-HSA-5358346
Immune System R-HSA-168256
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PTEN Regulation R-HSA-6807070
M Phase R-HSA-68886
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle Checkpoints R-HSA-69620
Degradation of DVL R-HSA-4641258
Mitotic G2-G2/M phases R-HSA-453274
Interleukin-1 signaling R-HSA-9020702
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RAS by GAPs R-HSA-5658442
Programmed Cell Death R-HSA-5357801
Cyclin E associated events during G1/S transition R-HSA-69202
MAPK6/MAPK4 signaling R-HSA-5687128
Metabolism R-HSA-1430728
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by NOTCH R-HSA-157118
Post-translational protein modification R-HSA-597592
Downstream TCR signaling R-HSA-202424
Regulation of expression of SLITs and ROBOs R-HSA-9010553
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PCP/CE pathway R-HSA-4086400
MAPK1/MAPK3 signaling R-HSA-5684996
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of mitotic cell cycle R-HSA-453276
Signal Transduction R-HSA-162582
RNA Polymerase II Transcription R-HSA-73857
HIV Infection R-HSA-162906
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cellular response to chemical stress R-HSA-9711123
Hedgehog 'off' state R-HSA-5610787
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Antigen processing-Cross presentation R-HSA-1236975
Regulation of PTEN stability and activity R-HSA-8948751
Nuclear events mediated by NFE2L2 R-HSA-9759194
Adaptive Immune System R-HSA-1280218
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of RNA R-HSA-8953854
Defective CFTR causes cystic fibrosis R-HSA-5678895
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disease R-HSA-1643685
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of RUNX3 expression and activity R-HSA-8941858
C-type lectin receptors (CLRs) R-HSA-5621481
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by Hedgehog R-HSA-5358351
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
ER-Phagosome pathway R-HSA-1236974
Regulation of mitotic cell cycle R-HSA-453276
HIV Infection R-HSA-162906
Hedgehog ligand biogenesis R-HSA-5358346
Interferon alpha/beta signaling R-HSA-909733
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of RUNX3 expression and activity R-HSA-8941858
G2/M Transition R-HSA-69275
MAPK6/MAPK4 signaling R-HSA-5687128
Antigen processing-Cross presentation R-HSA-1236975
G1/S Transition R-HSA-69206
DNA Replication R-HSA-69306
KEAP1-NFE2L2 pathway R-HSA-9755511
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Disorders of transmembrane transporters R-HSA-5619115
G1/S DNA Damage Checkpoints R-HSA-69615
Cellular response to chemical stress R-HSA-9711123
Cell Cycle Checkpoints R-HSA-69620
Generic Transcription Pathway R-HSA-212436
Regulation of Apoptosis R-HSA-169911
Orc1 removal from chromatin R-HSA-68949
Signaling by Interleukins R-HSA-449147
Metabolism R-HSA-1430728
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Vpu mediated degradation of CD4 R-HSA-180534
Cell Cycle, Mitotic R-HSA-69278
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Host Interactions of HIV factors R-HSA-162909
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
M Phase R-HSA-68886
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TCF dependent signaling in response to WNT R-HSA-201681
Synthesis of DNA R-HSA-69239
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Deubiquitination R-HSA-5688426
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
PCP/CE pathway R-HSA-4086400
Mitotic Anaphase R-HSA-68882
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Axon guidance R-HSA-422475
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transcriptional regulation by RUNX1 R-HSA-8878171
Class I MHC mediated antigen processing & presentation R-HSA-983169
Disease R-HSA-1643685
Nervous system development R-HSA-9675108
Hedgehog 'on' state R-HSA-5632684
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
FCERI mediated NF-kB activation R-HSA-2871837
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of RNA R-HSA-8953854
Signaling by NOTCH R-HSA-157118
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Mitotic G1 phase and G1/S transition R-HSA-453279
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
p53-Dependent G1 DNA Damage Response R-HSA-69563
RAF/MAP kinase cascade R-HSA-5673001
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Interleukin-1 signaling R-HSA-9020702
Switching of origins to a post-replicative state R-HSA-69052
Infectious disease R-HSA-5663205
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Neddylation R-HSA-8951664
Mitotic G2-G2/M phases R-HSA-453274
Post-translational protein modification R-HSA-597592
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PTEN Regulation R-HSA-6807070
Signaling by NOTCH4 R-HSA-9013694
Metabolism of amino acids and derivatives R-HSA-71291
Gene expression (Transcription) R-HSA-74160
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX2 R-HSA-8878166
Developmental Biology R-HSA-1266738
MAPK family signaling cascades R-HSA-5683057
Degradation of DVL R-HSA-4641258
Metabolism of proteins R-HSA-392499
Ub-specific processing proteases R-HSA-5689880
Separation of Sister Chromatids R-HSA-2467813
Cellular responses to stress R-HSA-2262752
Degradation of GLI2 by the proteasome R-HSA-5610783
Interleukin-1 family signaling R-HSA-446652
RNA Polymerase II Transcription R-HSA-73857
TCR signaling R-HSA-202403
Metabolism of polyamines R-HSA-351202
Programmed Cell Death R-HSA-5357801
Cellular response to hypoxia R-HSA-1234174
Apoptosis R-HSA-109581
Defective CFTR causes cystic fibrosis R-HSA-5678895
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of PTEN stability and activity R-HSA-8948751
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Hh mutants abrogate ligand secretion R-HSA-5387390
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
CLEC7A (Dectin-1) signaling R-HSA-5607764
DNA Replication Pre-Initiation R-HSA-69002
ABC transporter disorders R-HSA-5619084
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog 'off' state R-HSA-5610787
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interferon Signaling R-HSA-913531
Assembly of the pre-replicative complex R-HSA-68867
Degradation of AXIN R-HSA-4641257
Downstream TCR signaling R-HSA-202424
C-type lectin receptors (CLRs) R-HSA-5621481
Stabilization of p53 R-HSA-69541
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of beta-catenin by the destruction complex R-HSA-195253
Asymmetric localization of PCP proteins R-HSA-4608870
ABC-family proteins mediated transport R-HSA-382556
Immune System R-HSA-168256
Cellular responses to stimuli R-HSA-8953897
Adaptive Immune System R-HSA-1280218
Degradation of GLI1 by the proteasome R-HSA-5610780
Transport of small molecules R-HSA-382551
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of RAS by GAPs R-HSA-5658442
Signaling by ROBO receptors R-HSA-376176
Cytokine Signaling in Immune system R-HSA-1280215
UCH proteinases R-HSA-5689603
Negative regulation of NOTCH4 signaling R-HSA-9604323
S Phase R-HSA-69242
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by WNT R-HSA-195721
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Innate Immune System R-HSA-168249
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transcriptional regulation by RUNX3 R-HSA-8878159
G2/M Checkpoints R-HSA-69481
Disorders of transmembrane transporters R-HSA-5619115
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Separation of Sister Chromatids R-HSA-2467813
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of polyamines R-HSA-351202
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Infectious disease R-HSA-5663205
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hh mutants are degraded by ERAD R-HSA-5362768
DNA Replication Pre-Initiation R-HSA-69002
Cytokine Signaling in Immune system R-HSA-1280215
MAPK6/MAPK4 signaling R-HSA-5687128
Interferon alpha/beta signaling R-HSA-909733
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Orc1 removal from chromatin R-HSA-68949
Mitotic Metaphase and Anaphase R-HSA-2555396
Transcriptional regulation by RUNX3 R-HSA-8878159
Post-translational protein modification R-HSA-597592
DNA Replication R-HSA-69306
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Disease R-HSA-1643685
Regulation of RUNX2 expression and activity R-HSA-8939902
G1/S Transition R-HSA-69206
Mitotic Anaphase R-HSA-68882
NIK-->noncanonical NF-kB signaling R-HSA-5676590
RAF/MAP kinase cascade R-HSA-5673001
Ub-specific processing proteases R-HSA-5689880
Regulation of RAS by GAPs R-HSA-5658442
Asymmetric localization of PCP proteins R-HSA-4608870
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Assembly of the pre-replicative complex R-HSA-68867
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
S Phase R-HSA-69242
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
UCH proteinases R-HSA-5689603
CLEC7A (Dectin-1) signaling R-HSA-5607764
Stabilization of p53 R-HSA-69541
Transport of small molecules R-HSA-382551
Metabolism of RNA R-HSA-8953854
C-type lectin receptors (CLRs) R-HSA-5621481
Cellular response to chemical stress R-HSA-9711123
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
PTEN Regulation R-HSA-6807070
Signaling by WNT R-HSA-195721
Regulation of PTEN stability and activity R-HSA-8948751
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by NOTCH R-HSA-157118
Defective CFTR causes cystic fibrosis R-HSA-5678895
ABC-family proteins mediated transport R-HSA-382556
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
HIV Infection R-HSA-162906
Programmed Cell Death R-HSA-5357801
Metabolism of proteins R-HSA-392499
Class I MHC mediated antigen processing & presentation R-HSA-983169
PIP3 activates AKT signaling R-HSA-1257604
Axon guidance R-HSA-422475
Regulation of RUNX3 expression and activity R-HSA-8941858
Generic Transcription Pathway R-HSA-212436
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Signaling by Interleukins R-HSA-449147
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog 'off' state R-HSA-5610787
Metabolism R-HSA-1430728
ABC transporter disorders R-HSA-5619084
Cellular responses to stress R-HSA-2262752
Nuclear events mediated by NFE2L2 R-HSA-9759194
ER-Phagosome pathway R-HSA-1236974
TCR signaling R-HSA-202403
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle R-HSA-1640170
Immune System R-HSA-168256
Adaptive Immune System R-HSA-1280218
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
MAPK family signaling cascades R-HSA-5683057
p53-Dependent G1 DNA Damage Response R-HSA-69563
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of amino acids and derivatives R-HSA-71291
p53-Independent DNA Damage Response R-HSA-69610
Host Interactions of HIV factors R-HSA-162909
Vif-mediated degradation of APOBEC3G R-HSA-180585
Downstream TCR signaling R-HSA-202424
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog 'on' state R-HSA-5632684
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Synthesis of DNA R-HSA-69239
Signaling by NOTCH4 R-HSA-9013694
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hedgehog ligand biogenesis R-HSA-5358346
Cell Cycle, Mitotic R-HSA-69278
Regulation of Apoptosis R-HSA-169911
G1/S DNA Damage Checkpoints R-HSA-69615
Intracellular signaling by second messengers R-HSA-9006925
M Phase R-HSA-68886
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by ROBO receptors R-HSA-376176
Switching of origins to a post-replicative state R-HSA-69052
MAPK1/MAPK3 signaling R-HSA-5684996
Innate Immune System R-HSA-168249
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX1 R-HSA-8878171
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular responses to stimuli R-HSA-8953897
Interleukin-1 signaling R-HSA-9020702
Negative regulation of NOTCH4 signaling R-HSA-9604323
KEAP1-NFE2L2 pathway R-HSA-9755511
Interleukin-1 family signaling R-HSA-446652
PCP/CE pathway R-HSA-4086400
Transcriptional regulation by RUNX2 R-HSA-8878166
Nervous system development R-HSA-9675108
Interferon Signaling R-HSA-913531
Degradation of GLI1 by the proteasome R-HSA-5610780
Mitotic G1 phase and G1/S transition R-HSA-453279
Apoptosis R-HSA-109581
Beta-catenin independent WNT signaling R-HSA-3858494
Cyclin E associated events during G1/S transition R-HSA-69202
Neddylation R-HSA-8951664
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Mitotic G2-G2/M phases R-HSA-453274
Developmental Biology R-HSA-1266738
Degradation of GLI2 by the proteasome R-HSA-5610783
Signal Transduction R-HSA-162582
Cell Cycle Checkpoints R-HSA-69620
Deubiquitination R-HSA-5688426
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of AXIN R-HSA-4641257
Cellular response to hypoxia R-HSA-1234174
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G2/M Transition R-HSA-69275
G2/M Checkpoints R-HSA-69481
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of DVL R-HSA-4641258
Vpu mediated degradation of CD4 R-HSA-180534
Antigen processing-Cross presentation R-HSA-1236975
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Interleukin-1 signaling R-HSA-9020702
Transcriptional regulation by RUNX2 R-HSA-8878166
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G2/M Checkpoints R-HSA-69481
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of RAS by GAPs R-HSA-5658442
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RUNX3 expression and activity R-HSA-8941858
Programmed Cell Death R-HSA-5357801
Innate Immune System R-HSA-168249
Mitotic Anaphase R-HSA-68882
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH R-HSA-157118
Apoptosis R-HSA-109581
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Generic Transcription Pathway R-HSA-212436
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Orc1 removal from chromatin R-HSA-68949
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Host Interactions of HIV factors R-HSA-162909
Gene expression (Transcription) R-HSA-74160
Mitotic G2-G2/M phases R-HSA-453274
Immune System R-HSA-168256
Signaling by WNT R-HSA-195721
Infectious disease R-HSA-5663205
Degradation of DVL R-HSA-4641258
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Neddylation R-HSA-8951664
Assembly of the pre-replicative complex R-HSA-68867
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of AXIN R-HSA-4641257
Interferon Signaling R-HSA-913531
Activation of NF-kappaB in B cells R-HSA-1169091
Antigen processing-Cross presentation R-HSA-1236975
Interferon alpha/beta signaling R-HSA-909733
Signaling by Hedgehog R-HSA-5358351
Switching of origins to a post-replicative state R-HSA-69052
Disorders of transmembrane transporters R-HSA-5619115
G2/M Transition R-HSA-69275
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of mitotic cell cycle R-HSA-453276
RAF/MAP kinase cascade R-HSA-5673001
C-type lectin receptors (CLRs) R-HSA-5621481
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Adaptive Immune System R-HSA-1280218
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stimuli R-HSA-8953897
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of GLI2 by the proteasome R-HSA-5610783
Vpu mediated degradation of CD4 R-HSA-180534
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of Apoptosis R-HSA-169911
Developmental Biology R-HSA-1266738
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cell Cycle R-HSA-1640170
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Nervous system development R-HSA-9675108
Cellular responses to stress R-HSA-2262752
PCP/CE pathway R-HSA-4086400
Cytokine Signaling in Immune system R-HSA-1280215
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Axon guidance R-HSA-422475
M Phase R-HSA-68886
Degradation of beta-catenin by the destruction complex R-HSA-195253
Defective CFTR causes cystic fibrosis R-HSA-5678895
ER-Phagosome pathway R-HSA-1236974
Metabolism R-HSA-1430728
Metabolism of polyamines R-HSA-351202
Signaling by ROBO receptors R-HSA-376176
G1/S DNA Damage Checkpoints R-HSA-69615
Synthesis of DNA R-HSA-69239
TCR signaling R-HSA-202403
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular response to hypoxia R-HSA-1234174
Intracellular signaling by second messengers R-HSA-9006925
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cell Cycle Checkpoints R-HSA-69620
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication R-HSA-69306
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
MAPK1/MAPK3 signaling R-HSA-5684996
Post-translational protein modification R-HSA-597592
Regulation of RUNX2 expression and activity R-HSA-8939902
Asymmetric localization of PCP proteins R-HSA-4608870
Separation of Sister Chromatids R-HSA-2467813
ABC transporter disorders R-HSA-5619084
G1/S Transition R-HSA-69206
Metabolism of proteins R-HSA-392499
Hh mutants are degraded by ERAD R-HSA-5362768
DNA Replication Pre-Initiation R-HSA-69002
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
RNA Polymerase II Transcription R-HSA-73857
Signaling by Interleukins R-HSA-449147
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX3 R-HSA-8878159
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transport of small molecules R-HSA-382551
Downstream TCR signaling R-HSA-202424
PTEN Regulation R-HSA-6807070
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of PTEN stability and activity R-HSA-8948751
HIV Infection R-HSA-162906
p53-Dependent G1 DNA Damage Response R-HSA-69563
p53-Independent DNA Damage Response R-HSA-69610
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of RNA R-HSA-8953854
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog 'on' state R-HSA-5632684
Signaling by NOTCH4 R-HSA-9013694
PIP3 activates AKT signaling R-HSA-1257604
Deubiquitination R-HSA-5688426
Hedgehog ligand biogenesis R-HSA-5358346
S Phase R-HSA-69242
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
MAPK family signaling cascades R-HSA-5683057
TCF dependent signaling in response to WNT R-HSA-201681
UCH proteinases R-HSA-5689603
Interleukin-1 family signaling R-HSA-446652
Mitotic G1 phase and G1/S transition R-HSA-453279
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cellular response to chemical stress R-HSA-9711123
Hedgehog 'off' state R-HSA-5610787
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
ABC-family proteins mediated transport R-HSA-382556
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cell Cycle, Mitotic R-HSA-69278
Beta-catenin independent WNT signaling R-HSA-3858494
FCERI mediated NF-kB activation R-HSA-2871837
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Class I MHC mediated antigen processing & presentation R-HSA-983169
Ub-specific processing proteases R-HSA-5689880
Mitotic Metaphase and Anaphase R-HSA-2555396
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Stabilization of p53 R-HSA-69541
Interferon Signaling R-HSA-913531
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of AXIN R-HSA-4641257
M Phase R-HSA-68886
Negative regulation of NOTCH4 signaling R-HSA-9604323
Disease R-HSA-1643685
Mitotic Anaphase R-HSA-68882
Signaling by ROBO receptors R-HSA-376176
Transcriptional regulation by RUNX3 R-HSA-8878159
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCR signaling R-HSA-202403
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Interferon alpha/beta signaling R-HSA-909733
PTEN Regulation R-HSA-6807070
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
C-type lectin receptors (CLRs) R-HSA-5621481
G1/S Transition R-HSA-69206
Stabilization of p53 R-HSA-69541
Hh mutants abrogate ligand secretion R-HSA-5387390
Immune System R-HSA-168256
Signaling by Hedgehog R-HSA-5358351
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Generic Transcription Pathway R-HSA-212436
Interleukin-1 signaling R-HSA-9020702
Infectious disease R-HSA-5663205
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle Checkpoints R-HSA-69620
Signaling by Interleukins R-HSA-449147
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Checkpoints R-HSA-69481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Deubiquitination R-HSA-5688426
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of expression of SLITs and ROBOs R-HSA-9010553
HIV Infection R-HSA-162906
Axon guidance R-HSA-422475
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cellular response to hypoxia R-HSA-1234174
DNA Replication Pre-Initiation R-HSA-69002
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cell Cycle, Mitotic R-HSA-69278
Cellular response to chemical stress R-HSA-9711123
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Assembly of the pre-replicative complex R-HSA-68867
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Vpu mediated degradation of CD4 R-HSA-180534
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of DVL R-HSA-4641258
Regulation of Apoptosis R-HSA-169911
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Developmental Biology R-HSA-1266738
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Asymmetric localization of PCP proteins R-HSA-4608870
PCP/CE pathway R-HSA-4086400
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK1/MAPK3 signaling R-HSA-5684996
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic G1 phase and G1/S transition R-HSA-453279
Switching of origins to a post-replicative state R-HSA-69052
Neddylation R-HSA-8951664
Hedgehog 'on' state R-HSA-5632684
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream TCR signaling R-HSA-202424
Synthesis of DNA R-HSA-69239
Cyclin E associated events during G1/S transition R-HSA-69202
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
G1/S DNA Damage Checkpoints R-HSA-69615
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Separation of Sister Chromatids R-HSA-2467813
Cell Cycle R-HSA-1640170
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by NOTCH4 R-HSA-9013694
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of GLI2 by the proteasome R-HSA-5610783
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of mitotic cell cycle R-HSA-453276
Disorders of transmembrane transporters R-HSA-5619115
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
KEAP1-NFE2L2 pathway R-HSA-9755511
Intracellular signaling by second messengers R-HSA-9006925
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
DNA Replication R-HSA-69306
MAPK family signaling cascades R-HSA-5683057
Signaling by NOTCH R-HSA-157118
Regulation of PTEN stability and activity R-HSA-8948751
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
G2/M Transition R-HSA-69275
Interleukin-1 family signaling R-HSA-446652
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
NIK-->noncanonical NF-kB signaling R-HSA-5676590
ABC transporter disorders R-HSA-5619084
Host Interactions of HIV factors R-HSA-162909
Cellular responses to stress R-HSA-2262752
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Apoptosis R-HSA-109581
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cytokine Signaling in Immune system R-HSA-1280215
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PIP3 activates AKT signaling R-HSA-1257604
Class I MHC mediated antigen processing & presentation R-HSA-983169
Transport of small molecules R-HSA-382551
Metabolism of proteins R-HSA-392499
p53-Independent DNA Damage Response R-HSA-69610
S Phase R-HSA-69242
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
UCH proteinases R-HSA-5689603
ER-Phagosome pathway R-HSA-1236974
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism of polyamines R-HSA-351202
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of RAS by GAPs R-HSA-5658442
TCF dependent signaling in response to WNT R-HSA-201681
Transcriptional regulation by RUNX2 R-HSA-8878166
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by WNT R-HSA-195721
Degradation of beta-catenin by the destruction complex R-HSA-195253
Nervous system development R-HSA-9675108
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Activation of NF-kappaB in B cells R-HSA-1169091
Post-translational protein modification R-HSA-597592
Cellular responses to stimuli R-HSA-8953897
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog 'off' state R-HSA-5610787
Beta-catenin independent WNT signaling R-HSA-3858494
Programmed Cell Death R-HSA-5357801
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of RNA R-HSA-8953854
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Metabolism R-HSA-1430728
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Ub-specific processing proteases R-HSA-5689880
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Checkpoints R-HSA-69481
Infectious disease R-HSA-5663205
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of proteins R-HSA-392499
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Mitotic Metaphase and Anaphase R-HSA-2555396
Stabilization of p53 R-HSA-69541
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of RUNX2 expression and activity R-HSA-8939902
Asymmetric localization of PCP proteins R-HSA-4608870
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog 'on' state R-HSA-5632684
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Class I MHC mediated antigen processing & presentation R-HSA-983169
MAPK family signaling cascades R-HSA-5683057
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S DNA Damage Checkpoints R-HSA-69615
MAPK6/MAPK4 signaling R-HSA-5687128
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular response to chemical stress R-HSA-9711123
Cytokine Signaling in Immune system R-HSA-1280215
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 signaling R-HSA-9020702
Neddylation R-HSA-8951664
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Assembly of the pre-replicative complex R-HSA-68867
Disorders of transmembrane transporters R-HSA-5619115
Signal Transduction R-HSA-162582
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transport of small molecules R-HSA-382551
UCH proteinases R-HSA-5689603
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of beta-catenin by the destruction complex R-HSA-195253
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of AXIN R-HSA-4641257
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of GLI1 by the proteasome R-HSA-5610780
PIP3 activates AKT signaling R-HSA-1257604
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Host Interactions of HIV factors R-HSA-162909
Cell Cycle, Mitotic R-HSA-69278
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by Interleukins R-HSA-449147
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular responses to stimuli R-HSA-8953897
Signaling by WNT R-HSA-195721
Apoptosis R-HSA-109581
Interferon Signaling R-HSA-913531
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hh mutants are degraded by ERAD R-HSA-5362768
HIV Infection R-HSA-162906
Post-translational protein modification R-HSA-597592
Hh mutants abrogate ligand secretion R-HSA-5387390
Hedgehog ligand biogenesis R-HSA-5358346
Disease R-HSA-1643685
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Adaptive Immune System R-HSA-1280218
Metabolism R-HSA-1430728
Activation of NF-kappaB in B cells R-HSA-1169091
Orc1 removal from chromatin R-HSA-68949
Signaling by Hedgehog R-HSA-5358351
Cellular responses to stress R-HSA-2262752
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of DVL R-HSA-4641258
MAPK1/MAPK3 signaling R-HSA-5684996
G1/S Transition R-HSA-69206
Ub-specific processing proteases R-HSA-5689880
Cell Cycle R-HSA-1640170
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Generic Transcription Pathway R-HSA-212436
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
RAF/MAP kinase cascade R-HSA-5673001
G2/M Transition R-HSA-69275
Nervous system development R-HSA-9675108
M Phase R-HSA-68886
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Innate Immune System R-HSA-168249
Regulation of RUNX3 expression and activity R-HSA-8941858
Immune System R-HSA-168256
Vpu mediated degradation of CD4 R-HSA-180534
S Phase R-HSA-69242
Signaling by NOTCH4 R-HSA-9013694
Regulation of mitotic cell cycle R-HSA-453276
PCP/CE pathway R-HSA-4086400
Metabolism of polyamines R-HSA-351202
PTEN Regulation R-HSA-6807070
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
DNA Replication Pre-Initiation R-HSA-69002
Interferon alpha/beta signaling R-HSA-909733
Interleukin-1 family signaling R-HSA-446652
Cellular response to hypoxia R-HSA-1234174
Regulation of RAS by GAPs R-HSA-5658442
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cell Cycle Checkpoints R-HSA-69620
Transcriptional regulation by RUNX3 R-HSA-8878159
ER-Phagosome pathway R-HSA-1236974
TCR signaling R-HSA-202403
Hedgehog 'off' state R-HSA-5610787
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Gene expression (Transcription) R-HSA-74160
Deubiquitination R-HSA-5688426
RNA Polymerase II Transcription R-HSA-73857
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Synthesis of DNA R-HSA-69239
Regulation of Apoptosis R-HSA-169911
ABC-family proteins mediated transport R-HSA-382556
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic Anaphase R-HSA-68882
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic G2-G2/M phases R-HSA-453274
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by NOTCH R-HSA-157118
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
FCERI mediated NF-kB activation R-HSA-2871837
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Antigen processing-Cross presentation R-HSA-1236975
Transcriptional regulation by RUNX2 R-HSA-8878166
Intracellular signaling by second messengers R-HSA-9006925
Vif-mediated degradation of APOBEC3G R-HSA-180585
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism of amino acids and derivatives R-HSA-71291
DNA Replication R-HSA-69306
Axon guidance R-HSA-422475
Signaling by ROBO receptors R-HSA-376176
Downstream TCR signaling R-HSA-202424
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
p53-Dependent G1 DNA Damage Response R-HSA-69563
Switching of origins to a post-replicative state R-HSA-69052
Developmental Biology R-HSA-1266738
Separation of Sister Chromatids R-HSA-2467813
DNA Replication Pre-Initiation R-HSA-69002
Hh mutants abrogate ligand secretion R-HSA-5387390
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by WNT R-HSA-195721
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RUNX3 expression and activity R-HSA-8941858
Switching of origins to a post-replicative state R-HSA-69052
Hedgehog 'off' state R-HSA-5610787
Separation of Sister Chromatids R-HSA-2467813
ER-Phagosome pathway R-HSA-1236974
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of polyamines R-HSA-351202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of DVL R-HSA-4641258
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nuclear events mediated by NFE2L2 R-HSA-9759194
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog 'on' state R-HSA-5632684
S Phase R-HSA-69242
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RAF/MAP kinase cascade R-HSA-5673001
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Adaptive Immune System R-HSA-1280218
Stabilization of p53 R-HSA-69541
Degradation of GLI2 by the proteasome R-HSA-5610783
Cellular responses to stress R-HSA-2262752
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
ABC-family proteins mediated transport R-HSA-382556
Metabolism of RNA R-HSA-8953854
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic Metaphase and Anaphase R-HSA-2555396
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transcriptional regulation by RUNX1 R-HSA-8878171
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disorders of transmembrane transporters R-HSA-5619115
Asymmetric localization of PCP proteins R-HSA-4608870
Mitotic G1 phase and G1/S transition R-HSA-453279
Vpu mediated degradation of CD4 R-HSA-180534
Immune System R-HSA-168256
Defective CFTR causes cystic fibrosis R-HSA-5678895
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of beta-catenin by the destruction complex R-HSA-195253
Innate Immune System R-HSA-168249
Cellular response to chemical stress R-HSA-9711123
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Assembly of the pre-replicative complex R-HSA-68867
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Vif-mediated degradation of APOBEC3G R-HSA-180585
TCF dependent signaling in response to WNT R-HSA-201681
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cytokine Signaling in Immune system R-HSA-1280215
Synthesis of DNA R-HSA-69239
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G2-G2/M phases R-HSA-453274
Downstream TCR signaling R-HSA-202424
G1/S Transition R-HSA-69206
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Anaphase R-HSA-68882
Metabolism of amino acids and derivatives R-HSA-71291
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Nervous system development R-HSA-9675108
Programmed Cell Death R-HSA-5357801
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by NOTCH R-HSA-157118
Cell Cycle R-HSA-1640170
Signaling by ROBO receptors R-HSA-376176
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
CLEC7A (Dectin-1) signaling R-HSA-5607764
DNA Replication R-HSA-69306
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of Apoptosis R-HSA-169911
Transport of small molecules R-HSA-382551
M Phase R-HSA-68886
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
PTEN Regulation R-HSA-6807070
Disease R-HSA-1643685
ABC transporter disorders R-HSA-5619084
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cellular responses to stimuli R-HSA-8953897
Regulation of expression of SLITs and ROBOs R-HSA-9010553
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
C-type lectin receptors (CLRs) R-HSA-5621481
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cell Cycle Checkpoints R-HSA-69620
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX2 R-HSA-8878166
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Generic Transcription Pathway R-HSA-212436
Ub-specific processing proteases R-HSA-5689880
Interleukin-1 signaling R-HSA-9020702
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by Interleukins R-HSA-449147
PCP/CE pathway R-HSA-4086400
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX3 R-HSA-8878159
PIP3 activates AKT signaling R-HSA-1257604
Degradation of GLI1 by the proteasome R-HSA-5610780
FCERI mediated NF-kB activation R-HSA-2871837
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Transition R-HSA-69275
Metabolism R-HSA-1430728
Interferon Signaling R-HSA-913531
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX2 expression and activity R-HSA-8939902
Apoptosis R-HSA-109581
Hh mutants are degraded by ERAD R-HSA-5362768
G2/M Checkpoints R-HSA-69481
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Post-translational protein modification R-HSA-597592
Neddylation R-HSA-8951664
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCR signaling R-HSA-202403
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Interferon alpha/beta signaling R-HSA-909733
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
UCH proteinases R-HSA-5689603
Signaling by NOTCH4 R-HSA-9013694
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Axon guidance R-HSA-422475
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular response to hypoxia R-HSA-1234174
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RNA Polymerase II Transcription R-HSA-73857
HIV Infection R-HSA-162906
Degradation of AXIN R-HSA-4641257
Cyclin E associated events during G1/S transition R-HSA-69202
Developmental Biology R-HSA-1266738
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog ligand biogenesis R-HSA-5358346
Host Interactions of HIV factors R-HSA-162909
Signaling by Hedgehog R-HSA-5358351
Deubiquitination R-HSA-5688426
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Signal Transduction R-HSA-162582
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Orc1 removal from chromatin R-HSA-68949
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of proteins R-HSA-392499
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Interleukins R-HSA-449147
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Asymmetric localization of PCP proteins R-HSA-4608870
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Adaptive Immune System R-HSA-1280218
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hedgehog ligand biogenesis R-HSA-5358346
Mitotic G2-G2/M phases R-HSA-453274
G1/S DNA Damage Checkpoints R-HSA-69615
Immune System R-HSA-168256
Class I MHC mediated antigen processing & presentation R-HSA-983169
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of GLI1 by the proteasome R-HSA-5610780
G2/M Transition R-HSA-69275
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by NOTCH R-HSA-157118
Developmental Biology R-HSA-1266738
Degradation of AXIN R-HSA-4641257
Disease R-HSA-1643685
Hh mutants abrogate ligand secretion R-HSA-5387390
C-type lectin receptors (CLRs) R-HSA-5621481
G2/M Checkpoints R-HSA-69481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
M Phase R-HSA-68886
Cellular response to chemical stress R-HSA-9711123
p53-Independent DNA Damage Response R-HSA-69610
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Programmed Cell Death R-HSA-5357801
Deubiquitination R-HSA-5688426
Transcriptional regulation by RUNX3 R-HSA-8878159
Interferon alpha/beta signaling R-HSA-909733
Signaling by Hedgehog R-HSA-5358351
UCH proteinases R-HSA-5689603
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of mitotic cell cycle R-HSA-453276
Metabolism R-HSA-1430728
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transport of small molecules R-HSA-382551
Regulation of RAS by GAPs R-HSA-5658442
Stabilization of p53 R-HSA-69541
CLEC7A (Dectin-1) signaling R-HSA-5607764
Separation of Sister Chromatids R-HSA-2467813
Regulation of Apoptosis R-HSA-169911
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
ABC-family proteins mediated transport R-HSA-382556
S Phase R-HSA-69242
HIV Infection R-HSA-162906
Antigen processing-Cross presentation R-HSA-1236975
Signaling by NOTCH4 R-HSA-9013694
TCR signaling R-HSA-202403
KEAP1-NFE2L2 pathway R-HSA-9755511
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of polyamines R-HSA-351202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear events mediated by NFE2L2 R-HSA-9759194
Post-translational protein modification R-HSA-597592
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
Switching of origins to a post-replicative state R-HSA-69052
DNA Replication Pre-Initiation R-HSA-69002
Metabolism of proteins R-HSA-392499
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of GLI2 by the proteasome R-HSA-5610783
Generic Transcription Pathway R-HSA-212436
Mitotic Anaphase R-HSA-68882
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
Synthesis of DNA R-HSA-69239
Interleukin-1 signaling R-HSA-9020702
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interleukin-1 family signaling R-HSA-446652
Vpu mediated degradation of CD4 R-HSA-180534
Axon guidance R-HSA-422475
Interferon Signaling R-HSA-913531
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cellular response to hypoxia R-HSA-1234174
Host Interactions of HIV factors R-HSA-162909
Signaling by ROBO receptors R-HSA-376176
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of RUNX2 expression and activity R-HSA-8939902
G1/S Transition R-HSA-69206
ER-Phagosome pathway R-HSA-1236974
Cell Cycle R-HSA-1640170
MAPK6/MAPK4 signaling R-HSA-5687128
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
TCF dependent signaling in response to WNT R-HSA-201681
MAPK family signaling cascades R-HSA-5683057
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular responses to stress R-HSA-2262752
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Beta-catenin independent WNT signaling R-HSA-3858494
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic Metaphase and Anaphase R-HSA-2555396
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism of amino acids and derivatives R-HSA-71291
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog 'on' state R-HSA-5632684
Ub-specific processing proteases R-HSA-5689880
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hedgehog 'off' state R-HSA-5610787
Activation of NF-kappaB in B cells R-HSA-1169091
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Disorders of transmembrane transporters R-HSA-5619115
Hh mutants are degraded by ERAD R-HSA-5362768
Negative regulation of NOTCH4 signaling R-HSA-9604323
FCERI mediated NF-kB activation R-HSA-2871837
Cell Cycle Checkpoints R-HSA-69620
Cell Cycle, Mitotic R-HSA-69278
Degradation of DVL R-HSA-4641258
Signal Transduction R-HSA-162582
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Downstream TCR signaling R-HSA-202424
Cellular responses to stimuli R-HSA-8953897
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of PTEN stability and activity R-HSA-8948751
ABC transporter disorders R-HSA-5619084
Orc1 removal from chromatin R-HSA-68949
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by WNT R-HSA-195721
PTEN Regulation R-HSA-6807070
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Apoptosis R-HSA-109581
DNA Replication R-HSA-69306
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX1 R-HSA-8878171
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Neddylation R-HSA-8951664
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Assembly of the pre-replicative complex R-HSA-68867
PCP/CE pathway R-HSA-4086400

Expression Atlas ENSG00000204264
LRG display in Ensembl gene LRG_1328
NCBI gene (formerly Entrezgene) 5696
GeneCards 9545
HGNC Symbol HGNC:9545
MIM gene 177046
MIM morbid 256040
UniProtKB Gene Name X5D2R7
WikiGene 5696
Gene: PSMD3
Ensembl ID : ENSG00000108344
Description: proteasome 26S subunit, non-ATPase 3
Gene Synonyms: P58,RPN3,S3,TSTA2
5 APIs:
94 Possible Orthologues:

Apoptosis R-HSA-109581
Metabolism R-HSA-1430728
Apoptosis R-HSA-109581
Axon guidance R-HSA-422475
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of amino acids and derivatives R-HSA-71291
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of mitotic cell cycle R-HSA-453276
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Mitotic G1 phase and G1/S transition R-HSA-453279
Disease R-HSA-1643685
Mitotic Metaphase and Anaphase R-HSA-2555396
TCR signaling R-HSA-202403
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Switching of origins to a post-replicative state R-HSA-69052
Antigen processing-Cross presentation R-HSA-1236975
S Phase R-HSA-69242
Signaling by ROBO receptors R-HSA-376176
Asymmetric localization of PCP proteins R-HSA-4608870
ABC transporter disorders R-HSA-5619084
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism of RNA R-HSA-8953854
Hedgehog 'off' state R-HSA-5610787
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ABC-family proteins mediated transport R-HSA-382556
Ub-specific processing proteases R-HSA-5689880
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
TCF dependent signaling in response to WNT R-HSA-201681
Stabilization of p53 R-HSA-69541
Class I MHC mediated antigen processing & presentation R-HSA-983169
Neddylation R-HSA-8951664
Hh mutants are degraded by ERAD R-HSA-5362768
RNA Polymerase II Transcription R-HSA-73857
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI2 by the proteasome R-HSA-5610783
Innate Immune System R-HSA-168249
Programmed Cell Death R-HSA-5357801
G2/M Transition R-HSA-69275
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Synthesis of DNA R-HSA-69239
Intracellular signaling by second messengers R-HSA-9006925
Generic Transcription Pathway R-HSA-212436
Post-translational protein modification R-HSA-597592
Cellular response to chemical stress R-HSA-9711123
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Host Interactions of HIV factors R-HSA-162909
p53-Independent DNA Damage Response R-HSA-69610
Immune System R-HSA-168256
Signaling by NOTCH R-HSA-157118
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of Apoptosis R-HSA-169911
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Neutrophil degranulation R-HSA-6798695
RAF/MAP kinase cascade R-HSA-5673001
Degradation of AXIN R-HSA-4641257
Signaling by Hedgehog R-HSA-5358351
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of GLI1 by the proteasome R-HSA-5610780
Adaptive Immune System R-HSA-1280218
UCH proteinases R-HSA-5689603
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by Interleukins R-HSA-449147
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cyclin E associated events during G1/S transition R-HSA-69202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Transcriptional regulation by RUNX2 R-HSA-8878166
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by NOTCH4 R-HSA-9013694
Cytokine Signaling in Immune system R-HSA-1280215
Nervous system development R-HSA-9675108
Interleukin-1 family signaling R-HSA-446652
C-type lectin receptors (CLRs) R-HSA-5621481
Assembly of the pre-replicative complex R-HSA-68867
M Phase R-HSA-68886
Downstream TCR signaling R-HSA-202424
PCP/CE pathway R-HSA-4086400
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Metabolism of proteins R-HSA-392499
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Deubiquitination R-HSA-5688426
Cell Cycle, Mitotic R-HSA-69278
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle R-HSA-1640170
DNA Replication R-HSA-69306
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
KEAP1-NFE2L2 pathway R-HSA-9755511
Activation of NF-kappaB in B cells R-HSA-1169091
HIV Infection R-HSA-162906
ER-Phagosome pathway R-HSA-1236974
Axon guidance R-HSA-422475
Degradation of beta-catenin by the destruction complex R-HSA-195253
Gene expression (Transcription) R-HSA-74160
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Disorders of transmembrane transporters R-HSA-5619115
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism R-HSA-1430728
Cellular responses to stress R-HSA-2262752
Mitotic Anaphase R-HSA-68882
PIP3 activates AKT signaling R-HSA-1257604
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Separation of Sister Chromatids R-HSA-2467813
Infectious disease R-HSA-5663205
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Defective CFTR causes cystic fibrosis R-HSA-5678895
MAPK6/MAPK4 signaling R-HSA-5687128
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Orc1 removal from chromatin R-HSA-68949
Metabolism of polyamines R-HSA-351202
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Checkpoints R-HSA-69481
PTEN Regulation R-HSA-6807070
MAPK family signaling cascades R-HSA-5683057
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by WNT R-HSA-195721
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
FCERI mediated NF-kB activation R-HSA-2871837
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'on' state R-HSA-5632684
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 signaling R-HSA-9020702
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular responses to stimuli R-HSA-8953897
Transport of small molecules R-HSA-382551
DNA Replication Pre-Initiation R-HSA-69002
Apoptosis R-HSA-109581
Degradation of DVL R-HSA-4641258
Hedgehog ligand biogenesis R-HSA-5358346
MAPK1/MAPK3 signaling R-HSA-5684996
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G1/S Transition R-HSA-69206
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular response to hypoxia R-HSA-1234174
Regulation of RUNX2 expression and activity R-HSA-8939902
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Neddylation R-HSA-8951664
Regulation of RUNX3 expression and activity R-HSA-8941858
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
M Phase R-HSA-68886
Stabilization of p53 R-HSA-69541
Cellular responses to stimuli R-HSA-8953897
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of proteins R-HSA-392499
RAF/MAP kinase cascade R-HSA-5673001
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Nuclear events mediated by NFE2L2 R-HSA-9759194
TCR signaling R-HSA-202403
Asymmetric localization of PCP proteins R-HSA-4608870
G1/S DNA Damage Checkpoints R-HSA-69615
Deubiquitination R-HSA-5688426
Metabolism R-HSA-1430728
Generic Transcription Pathway R-HSA-212436
Nervous system development R-HSA-9675108
HIV Infection R-HSA-162906
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Axon guidance R-HSA-422475
Cell Cycle R-HSA-1640170
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle Checkpoints R-HSA-69620
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
RNA Polymerase II Transcription R-HSA-73857
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of polyamines R-HSA-351202
PCP/CE pathway R-HSA-4086400
Disorders of transmembrane transporters R-HSA-5619115
Orc1 removal from chromatin R-HSA-68949
Cellular response to hypoxia R-HSA-1234174
KEAP1-NFE2L2 pathway R-HSA-9755511
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Switching of origins to a post-replicative state R-HSA-69052
Signaling by NOTCH4 R-HSA-9013694
Signaling by ROBO receptors R-HSA-376176
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
S Phase R-HSA-69242
Disease R-HSA-1643685
FCERI mediated NF-kB activation R-HSA-2871837
Metabolism of amino acids and derivatives R-HSA-71291
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog 'off' state R-HSA-5610787
ABC transporter disorders R-HSA-5619084
Regulation of Apoptosis R-HSA-169911
Degradation of DVL R-HSA-4641258
DNA Replication R-HSA-69306
Degradation of GLI2 by the proteasome R-HSA-5610783
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
Host Interactions of HIV factors R-HSA-162909
G2/M Checkpoints R-HSA-69481
Signaling by WNT R-HSA-195721
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cell Cycle, Mitotic R-HSA-69278
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX3 R-HSA-8878159
Degradation of beta-catenin by the destruction complex R-HSA-195253
Vif-mediated degradation of APOBEC3G R-HSA-180585
Hh mutants abrogate ligand secretion R-HSA-5387390
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Separation of Sister Chromatids R-HSA-2467813
p53-Independent DNA Damage Response R-HSA-69610
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stress R-HSA-2262752
Mitotic G1 phase and G1/S transition R-HSA-453279
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transport of small molecules R-HSA-382551
Transcriptional regulation by RUNX2 R-HSA-8878166
Adaptive Immune System R-HSA-1280218
Signaling by Interleukins R-HSA-449147
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of RNA R-HSA-8953854
Gene expression (Transcription) R-HSA-74160
Programmed Cell Death R-HSA-5357801
Vpu mediated degradation of CD4 R-HSA-180534
Neutrophil degranulation R-HSA-6798695
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PIP3 activates AKT signaling R-HSA-1257604
Interleukin-1 signaling R-HSA-9020702
MAPK6/MAPK4 signaling R-HSA-5687128
Synthesis of DNA R-HSA-69239
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Developmental Biology R-HSA-1266738
Class I MHC mediated antigen processing & presentation R-HSA-983169
MAPK1/MAPK3 signaling R-HSA-5684996
DNA Replication Pre-Initiation R-HSA-69002
MAPK family signaling cascades R-HSA-5683057
Downstream TCR signaling R-HSA-202424
Antigen processing-Cross presentation R-HSA-1236975
Hedgehog ligand biogenesis R-HSA-5358346
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of AXIN R-HSA-4641257
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
C-type lectin receptors (CLRs) R-HSA-5621481
Ub-specific processing proteases R-HSA-5689880
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Transition R-HSA-69275
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) signaling R-HSA-5607764
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
PTEN Regulation R-HSA-6807070
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cytokine Signaling in Immune system R-HSA-1280215
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Innate Immune System R-HSA-168249
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
UCH proteinases R-HSA-5689603
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by Hedgehog R-HSA-5358351
Hedgehog 'on' state R-HSA-5632684
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
ABC-family proteins mediated transport R-HSA-382556
Post-translational protein modification R-HSA-597592
Cellular response to chemical stress R-HSA-9711123
Assembly of the pre-replicative complex R-HSA-68867
Interleukin-1 family signaling R-HSA-446652
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signal Transduction R-HSA-162582
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by NOTCH R-HSA-157118
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of mitotic cell cycle R-HSA-453276
Mitotic Anaphase R-HSA-68882
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Dependent G1 DNA Damage Response R-HSA-69563
G1/S Transition R-HSA-69206
G2/M Transition R-HSA-69275
Vpu mediated degradation of CD4 R-HSA-180534
Nervous system development R-HSA-9675108
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Developmental Biology R-HSA-1266738
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of RAS by GAPs R-HSA-5658442
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of Apoptosis R-HSA-169911
Cell Cycle, Mitotic R-HSA-69278
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G1/S Transition R-HSA-69206
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Orc1 removal from chromatin R-HSA-68949
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Mitotic G1 phase and G1/S transition R-HSA-453279
Synthesis of DNA R-HSA-69239
Signaling by NOTCH R-HSA-157118
TCR signaling R-HSA-202403
S Phase R-HSA-69242
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of GLI1 by the proteasome R-HSA-5610780
Cell Cycle Checkpoints R-HSA-69620
Signal Transduction R-HSA-162582
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of polyamines R-HSA-351202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
ABC transporter disorders R-HSA-5619084
Degradation of DVL R-HSA-4641258
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
RNA Polymerase II Transcription R-HSA-73857
PCP/CE pathway R-HSA-4086400
PTEN Regulation R-HSA-6807070
Programmed Cell Death R-HSA-5357801
Downstream TCR signaling R-HSA-202424
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 family signaling R-HSA-446652
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of beta-catenin by the destruction complex R-HSA-195253
Ub-specific processing proteases R-HSA-5689880
Cellular response to chemical stress R-HSA-9711123
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Asymmetric localization of PCP proteins R-HSA-4608870
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by NOTCH4 R-HSA-9013694
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cyclin E associated events during G1/S transition R-HSA-69202
UCH proteinases R-HSA-5689603
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of GLI2 by the proteasome R-HSA-5610783
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog ligand biogenesis R-HSA-5358346
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Neddylation R-HSA-8951664
Hedgehog 'off' state R-HSA-5610787
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of AXIN R-HSA-4641257
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by WNT R-HSA-195721
p53-Dependent G1 DNA Damage Response R-HSA-69563
Host Interactions of HIV factors R-HSA-162909
G2/M Checkpoints R-HSA-69481
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
DNA Replication Pre-Initiation R-HSA-69002
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Disease R-HSA-1643685
KEAP1-NFE2L2 pathway R-HSA-9755511
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular response to hypoxia R-HSA-1234174
C-type lectin receptors (CLRs) R-HSA-5621481
Switching of origins to a post-replicative state R-HSA-69052
Mitotic Anaphase R-HSA-68882
Transport of small molecules R-HSA-382551
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by Hedgehog R-HSA-5358351
Apoptosis R-HSA-109581
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cytokine Signaling in Immune system R-HSA-1280215
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Activation of NF-kappaB in B cells R-HSA-1169091
HIV Infection R-HSA-162906
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of RUNX2 expression and activity R-HSA-8939902
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Gene expression (Transcription) R-HSA-74160
DNA Replication R-HSA-69306
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Infectious disease R-HSA-5663205
Regulation of mitotic cell cycle R-HSA-453276
Intracellular signaling by second messengers R-HSA-9006925
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Axon guidance R-HSA-422475
p53-Independent DNA Damage Response R-HSA-69610
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
ER-Phagosome pathway R-HSA-1236974
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of amino acids and derivatives R-HSA-71291
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by Interleukins R-HSA-449147
Separation of Sister Chromatids R-HSA-2467813
RAF/MAP kinase cascade R-HSA-5673001
TCF dependent signaling in response to WNT R-HSA-201681
Antigen processing-Cross presentation R-HSA-1236975
Neutrophil degranulation R-HSA-6798695
Interleukin-1 signaling R-HSA-9020702
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Stabilization of p53 R-HSA-69541
Adaptive Immune System R-HSA-1280218
Assembly of the pre-replicative complex R-HSA-68867
Deubiquitination R-HSA-5688426
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism of RNA R-HSA-8953854
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK family signaling cascades R-HSA-5683057
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ABC-family proteins mediated transport R-HSA-382556
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle R-HSA-1640170
Mitotic G2-G2/M phases R-HSA-453274
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of proteins R-HSA-392499
M Phase R-HSA-68886
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog 'on' state R-HSA-5632684
Cellular responses to stimuli R-HSA-8953897
Transcriptional regulation by RUNX2 R-HSA-8878166
Post-translational protein modification R-HSA-597592
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by ROBO receptors R-HSA-376176
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Vif-mediated degradation of APOBEC3G R-HSA-180585
CLEC7A (Dectin-1) signaling R-HSA-5607764
Innate Immune System R-HSA-168249
DNA Replication R-HSA-69306
Transcriptional regulation by RUNX2 R-HSA-8878166
Antigen processing-Cross presentation R-HSA-1236975
PTEN Regulation R-HSA-6807070
Regulation of RAS by GAPs R-HSA-5658442
PCP/CE pathway R-HSA-4086400
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Separation of Sister Chromatids R-HSA-2467813
Hh mutants are degraded by ERAD R-HSA-5362768
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transport of small molecules R-HSA-382551
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle Checkpoints R-HSA-69620
Vpu mediated degradation of CD4 R-HSA-180534
S Phase R-HSA-69242
Cellular response to hypoxia R-HSA-1234174
MAPK1/MAPK3 signaling R-HSA-5684996
Assembly of the pre-replicative complex R-HSA-68867
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Infectious disease R-HSA-5663205
Cell Cycle R-HSA-1640170
Cytokine Signaling in Immune system R-HSA-1280215
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RUNX3 expression and activity R-HSA-8941858
Cyclin E associated events during G1/S transition R-HSA-69202
UCH proteinases R-HSA-5689603
Stabilization of p53 R-HSA-69541
M Phase R-HSA-68886
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Generic Transcription Pathway R-HSA-212436
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog ligand biogenesis R-HSA-5358346
ABC transporter disorders R-HSA-5619084
Ub-specific processing proteases R-HSA-5689880
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic G2-G2/M phases R-HSA-453274
G1/S DNA Damage Checkpoints R-HSA-69615
Axon guidance R-HSA-422475
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by ROBO receptors R-HSA-376176
Interleukin-1 family signaling R-HSA-446652
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Synthesis of DNA R-HSA-69239
Degradation of DVL R-HSA-4641258
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Switching of origins to a post-replicative state R-HSA-69052
Programmed Cell Death R-HSA-5357801
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by Interleukins R-HSA-449147
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Adaptive Immune System R-HSA-1280218
Intracellular signaling by second messengers R-HSA-9006925
TCR signaling R-HSA-202403
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Hedgehog R-HSA-5358351
Cellular responses to stress R-HSA-2262752
RNA Polymerase II Transcription R-HSA-73857
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Independent DNA Damage Response R-HSA-69610
RAF/MAP kinase cascade R-HSA-5673001
Mitotic Anaphase R-HSA-68882
Interleukin-1 signaling R-HSA-9020702
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Host Interactions of HIV factors R-HSA-162909
Degradation of AXIN R-HSA-4641257
ER-Phagosome pathway R-HSA-1236974
Downstream TCR signaling R-HSA-202424
Degradation of beta-catenin by the destruction complex R-HSA-195253
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of GLI1 by the proteasome R-HSA-5610780
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of Apoptosis R-HSA-169911
Signaling by WNT R-HSA-195721
Gene expression (Transcription) R-HSA-74160
Metabolism R-HSA-1430728
Cellular response to chemical stress R-HSA-9711123
G2/M Transition R-HSA-69275
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Asymmetric localization of PCP proteins R-HSA-4608870
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Apoptosis R-HSA-109581
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH4 R-HSA-9013694
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
PIP3 activates AKT signaling R-HSA-1257604
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of polyamines R-HSA-351202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
HIV Infection R-HSA-162906
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
MAPK family signaling cascades R-HSA-5683057
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
G2/M Checkpoints R-HSA-69481
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Dependent G1 DNA Damage Response R-HSA-69563
Transcriptional regulation by RUNX1 R-HSA-8878171
Post-translational protein modification R-HSA-597592
Immune System R-HSA-168256
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of proteins R-HSA-392499
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX3 R-HSA-8878159
Neutrophil degranulation R-HSA-6798695
Degradation of GLI2 by the proteasome R-HSA-5610783
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Disease R-HSA-1643685
Deubiquitination R-HSA-5688426
Signaling by NOTCH R-HSA-157118
Metabolism of RNA R-HSA-8953854
Nervous system development R-HSA-9675108
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of PTEN stability and activity R-HSA-8948751
KEAP1-NFE2L2 pathway R-HSA-9755511
Signal Transduction R-HSA-162582
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular responses to stimuli R-HSA-8953897
Activation of NF-kappaB in B cells R-HSA-1169091
TCF dependent signaling in response to WNT R-HSA-201681
G1/S Transition R-HSA-69206
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ABC-family proteins mediated transport R-HSA-382556
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cell Cycle, Mitotic R-HSA-69278
Hedgehog 'on' state R-HSA-5632684
MAPK6/MAPK4 signaling R-HSA-5687128
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of RUNX2 expression and activity R-HSA-8939902
Disorders of transmembrane transporters R-HSA-5619115
Neddylation R-HSA-8951664
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular responses to stress R-HSA-2262752
Defective CFTR causes cystic fibrosis R-HSA-5678895
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Negative regulation of NOTCH4 signaling R-HSA-9604323
Switching of origins to a post-replicative state R-HSA-69052
Regulation of RAS by GAPs R-HSA-5658442
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cell Cycle, Mitotic R-HSA-69278
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cellular response to hypoxia R-HSA-1234174
ABC transporter disorders R-HSA-5619084
Cell Cycle R-HSA-1640170
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
ER-Phagosome pathway R-HSA-1236974
Hedgehog ligand biogenesis R-HSA-5358346
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Immune System R-HSA-168256
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of DVL R-HSA-4641258
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Neddylation R-HSA-8951664
Cell Cycle Checkpoints R-HSA-69620
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by NOTCH R-HSA-157118
M Phase R-HSA-68886
Adaptive Immune System R-HSA-1280218
Apoptosis R-HSA-109581
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Gene expression (Transcription) R-HSA-74160
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Mitotic G1 phase and G1/S transition R-HSA-453279
Host Interactions of HIV factors R-HSA-162909
Regulation of mitotic cell cycle R-HSA-453276
Intracellular signaling by second messengers R-HSA-9006925
DNA Replication Pre-Initiation R-HSA-69002
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hh mutants are degraded by ERAD R-HSA-5362768
p53-Dependent G1 DNA Damage Response R-HSA-69563
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
KEAP1-NFE2L2 pathway R-HSA-9755511
Interleukin-1 family signaling R-HSA-446652
Innate Immune System R-HSA-168249
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX2 R-HSA-8878166
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Class I MHC mediated antigen processing & presentation R-HSA-983169
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Post-translational protein modification R-HSA-597592
Hedgehog 'on' state R-HSA-5632684
RNA Polymerase II Transcription R-HSA-73857
Ub-specific processing proteases R-HSA-5689880
Mitotic G2-G2/M phases R-HSA-453274
Beta-catenin independent WNT signaling R-HSA-3858494
Signal Transduction R-HSA-162582
Signaling by WNT R-HSA-195721
Signaling by Hedgehog R-HSA-5358351
Disorders of transmembrane transporters R-HSA-5619115
Metabolism R-HSA-1430728
Degradation of beta-catenin by the destruction complex R-HSA-195253
Synthesis of DNA R-HSA-69239
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic Anaphase R-HSA-68882
p53-Independent DNA Damage Response R-HSA-69610
TCR signaling R-HSA-202403
Nuclear events mediated by NFE2L2 R-HSA-9759194
Downstream TCR signaling R-HSA-202424
Deubiquitination R-HSA-5688426
Signaling by ROBO receptors R-HSA-376176
MAPK6/MAPK4 signaling R-HSA-5687128
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of AXIN R-HSA-4641257
ABC-family proteins mediated transport R-HSA-382556
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transcriptional regulation by RUNX1 R-HSA-8878171
Antigen processing-Cross presentation R-HSA-1236975
Transcriptional regulation by RUNX3 R-HSA-8878159
Infectious disease R-HSA-5663205
Regulation of RUNX2 expression and activity R-HSA-8939902
FCERI mediated NF-kB activation R-HSA-2871837
Transport of small molecules R-HSA-382551
Regulation of Apoptosis R-HSA-169911
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Nervous system development R-HSA-9675108
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by Interleukins R-HSA-449147
Cyclin E associated events during G1/S transition R-HSA-69202
Separation of Sister Chromatids R-HSA-2467813
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
S Phase R-HSA-69242
Interleukin-1 signaling R-HSA-9020702
PIP3 activates AKT signaling R-HSA-1257604
Axon guidance R-HSA-422475
Orc1 removal from chromatin R-HSA-68949
MAPK1/MAPK3 signaling R-HSA-5684996
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Stabilization of p53 R-HSA-69541
G1/S DNA Damage Checkpoints R-HSA-69615
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PCP/CE pathway R-HSA-4086400
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hh mutants abrogate ligand secretion R-HSA-5387390
PTEN Regulation R-HSA-6807070
Mitotic Metaphase and Anaphase R-HSA-2555396
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by NOTCH4 R-HSA-9013694
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RUNX3 expression and activity R-HSA-8941858
Programmed Cell Death R-HSA-5357801
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cytokine Signaling in Immune system R-HSA-1280215
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of RNA R-HSA-8953854
G2/M Checkpoints R-HSA-69481
Metabolism of proteins R-HSA-392499
Regulation of PTEN stability and activity R-HSA-8948751
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RAF/MAP kinase cascade R-HSA-5673001
HIV Infection R-HSA-162906
Metabolism of polyamines R-HSA-351202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
NIK-->noncanonical NF-kB signaling R-HSA-5676590
G2/M Transition R-HSA-69275
DNA Replication R-HSA-69306
Generic Transcription Pathway R-HSA-212436
Cellular responses to stimuli R-HSA-8953897
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Neutrophil degranulation R-HSA-6798695
UCH proteinases R-HSA-5689603
Cellular response to chemical stress R-HSA-9711123
Assembly of the pre-replicative complex R-HSA-68867
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
G1/S Transition R-HSA-69206
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Immune System R-HSA-168256
TCF dependent signaling in response to WNT R-HSA-201681
p53-Dependent G1 DNA Damage Response R-HSA-69563
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'on' state R-HSA-5632684
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by NOTCH4 R-HSA-9013694
Neddylation R-HSA-8951664
Signaling by WNT R-HSA-195721
Cell Cycle Checkpoints R-HSA-69620
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Post-translational protein modification R-HSA-597592
Signaling by ROBO receptors R-HSA-376176
Downstream TCR signaling R-HSA-202424
Signal Transduction R-HSA-162582
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Developmental Biology R-HSA-1266738
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular response to chemical stress R-HSA-9711123
G1/S DNA Damage Checkpoints R-HSA-69615
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of mitotic cell cycle R-HSA-453276
Signaling by Hedgehog R-HSA-5358351
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Replication R-HSA-69306
Stabilization of p53 R-HSA-69541
Interleukin-1 signaling R-HSA-9020702
Transcriptional regulation by RUNX3 R-HSA-8878159
Cell Cycle, Mitotic R-HSA-69278
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
M Phase R-HSA-68886
Infectious disease R-HSA-5663205
Mitotic G2-G2/M phases R-HSA-453274
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
DNA Replication Pre-Initiation R-HSA-69002
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Vif-mediated degradation of APOBEC3G R-HSA-180585
Class I MHC mediated antigen processing & presentation R-HSA-983169
MAPK6/MAPK4 signaling R-HSA-5687128
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of polyamines R-HSA-351202
Defective CFTR causes cystic fibrosis R-HSA-5678895
Axon guidance R-HSA-422475
PCP/CE pathway R-HSA-4086400
Degradation of DVL R-HSA-4641258
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
RNA Polymerase II Transcription R-HSA-73857
Intracellular signaling by second messengers R-HSA-9006925
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Ub-specific processing proteases R-HSA-5689880
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
RAF/MAP kinase cascade R-HSA-5673001
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Separation of Sister Chromatids R-HSA-2467813
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of amino acids and derivatives R-HSA-71291
Innate Immune System R-HSA-168249
Assembly of the pre-replicative complex R-HSA-68867
Programmed Cell Death R-HSA-5357801
Switching of origins to a post-replicative state R-HSA-69052
Deubiquitination R-HSA-5688426
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Anaphase R-HSA-68882
Disease R-HSA-1643685
Degradation of beta-catenin by the destruction complex R-HSA-195253
Mitotic G1 phase and G1/S transition R-HSA-453279
Generic Transcription Pathway R-HSA-212436
Metabolism R-HSA-1430728
Orc1 removal from chromatin R-HSA-68949
FCERI mediated NF-kB activation R-HSA-2871837
G2/M Checkpoints R-HSA-69481
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Beta-catenin independent WNT signaling R-HSA-3858494
Gene expression (Transcription) R-HSA-74160
Nuclear events mediated by NFE2L2 R-HSA-9759194
KEAP1-NFE2L2 pathway R-HSA-9755511
UCH proteinases R-HSA-5689603
Vpu mediated degradation of CD4 R-HSA-180534
ABC-family proteins mediated transport R-HSA-382556
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G2/M Transition R-HSA-69275
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cytokine Signaling in Immune system R-HSA-1280215
Neutrophil degranulation R-HSA-6798695
PIP3 activates AKT signaling R-HSA-1257604
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of PTEN stability and activity R-HSA-8948751
MAPK family signaling cascades R-HSA-5683057
G1/S Transition R-HSA-69206
Interleukin-1 family signaling R-HSA-446652
ABC transporter disorders R-HSA-5619084
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ER-Phagosome pathway R-HSA-1236974
PTEN Regulation R-HSA-6807070
CLEC7A (Dectin-1) signaling R-HSA-5607764
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cellular responses to stress R-HSA-2262752
Signaling by NOTCH R-HSA-157118
Cell Cycle R-HSA-1640170
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by Interleukins R-HSA-449147
Host Interactions of HIV factors R-HSA-162909
MAPK1/MAPK3 signaling R-HSA-5684996
Activation of NF-kappaB in B cells R-HSA-1169091
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog ligand biogenesis R-HSA-5358346
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX1 R-HSA-8878171
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of proteins R-HSA-392499
HIV Infection R-HSA-162906
Regulation of RUNX2 expression and activity R-HSA-8939902
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transcriptional regulation by RUNX2 R-HSA-8878166
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
S Phase R-HSA-69242
Cellular response to hypoxia R-HSA-1234174
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transport of small molecules R-HSA-382551
Mitotic Metaphase and Anaphase R-HSA-2555396
Adaptive Immune System R-HSA-1280218
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Nervous system development R-HSA-9675108
TCR signaling R-HSA-202403
Cellular responses to stimuli R-HSA-8953897
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of RNA R-HSA-8953854
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of Apoptosis R-HSA-169911
Synthesis of DNA R-HSA-69239
Regulation of RUNX3 expression and activity R-HSA-8941858
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Degradation of AXIN R-HSA-4641257
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI1 by the proteasome R-HSA-5610780
Cellular responses to stress R-HSA-2262752
MAPK1/MAPK3 signaling R-HSA-5684996
ABC-family proteins mediated transport R-HSA-382556
Beta-catenin independent WNT signaling R-HSA-3858494
ABC transporter disorders R-HSA-5619084
Post-translational protein modification R-HSA-597592
Hh mutants abrogate ligand secretion R-HSA-5387390
Asymmetric localization of PCP proteins R-HSA-4608870
Mitotic G2-G2/M phases R-HSA-453274
Metabolism R-HSA-1430728
Transcriptional regulation by RUNX3 R-HSA-8878159
G2/M Checkpoints R-HSA-69481
KEAP1-NFE2L2 pathway R-HSA-9755511
M Phase R-HSA-68886
MAPK family signaling cascades R-HSA-5683057
DNA Replication Pre-Initiation R-HSA-69002
Degradation of DVL R-HSA-4641258
RNA Polymerase II Transcription R-HSA-73857
Host Interactions of HIV factors R-HSA-162909
Activation of NF-kappaB in B cells R-HSA-1169091
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Separation of Sister Chromatids R-HSA-2467813
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Adaptive Immune System R-HSA-1280218
Cell Cycle Checkpoints R-HSA-69620
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular response to chemical stress R-HSA-9711123
PCP/CE pathway R-HSA-4086400
p53-Independent DNA Damage Response R-HSA-69610
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Transition R-HSA-69275
Nervous system development R-HSA-9675108
Regulation of RUNX2 expression and activity R-HSA-8939902
Hh mutants are degraded by ERAD R-HSA-5362768
Assembly of the pre-replicative complex R-HSA-68867
DNA Replication R-HSA-69306
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G1/S Transition R-HSA-69206
Cellular responses to stimuli R-HSA-8953897
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of polyamines R-HSA-351202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Ub-specific processing proteases R-HSA-5689880
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Negative regulation of NOTCH4 signaling R-HSA-9604323
HIV Infection R-HSA-162906
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signal Transduction R-HSA-162582
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Developmental Biology R-HSA-1266738
Signaling by NOTCH4 R-HSA-9013694
Regulation of Apoptosis R-HSA-169911
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Immune System R-HSA-168256
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of GLI1 by the proteasome R-HSA-5610780
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Switching of origins to a post-replicative state R-HSA-69052
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Interleukin-1 family signaling R-HSA-446652
UCH proteinases R-HSA-5689603
G1/S DNA Damage Checkpoints R-HSA-69615
Class I MHC mediated antigen processing & presentation R-HSA-983169
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Hedgehog 'off' state R-HSA-5610787
Transport of small molecules R-HSA-382551
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Vif-mediated degradation of APOBEC3G R-HSA-180585
Downstream TCR signaling R-HSA-202424
Mitotic G1 phase and G1/S transition R-HSA-453279
Synthesis of DNA R-HSA-69239
Apoptosis R-HSA-109581
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of mitotic cell cycle R-HSA-453276
Gene expression (Transcription) R-HSA-74160
Deubiquitination R-HSA-5688426
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
PIP3 activates AKT signaling R-HSA-1257604
Signaling by WNT R-HSA-195721
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RAS by GAPs R-HSA-5658442
Disease R-HSA-1643685
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
FCERI mediated NF-kB activation R-HSA-2871837
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
PTEN Regulation R-HSA-6807070
Degradation of GLI2 by the proteasome R-HSA-5610783
Cyclin E associated events during G1/S transition R-HSA-69202
Hedgehog 'on' state R-HSA-5632684
TCF dependent signaling in response to WNT R-HSA-201681
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
C-type lectin receptors (CLRs) R-HSA-5621481
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Programmed Cell Death R-HSA-5357801
Signaling by Interleukins R-HSA-449147
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Interleukin-1 signaling R-HSA-9020702
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cell Cycle, Mitotic R-HSA-69278
Stabilization of p53 R-HSA-69541
Hedgehog ligand biogenesis R-HSA-5358346
Innate Immune System R-HSA-168249
Intracellular signaling by second messengers R-HSA-9006925
Antigen processing-Cross presentation R-HSA-1236975
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of proteins R-HSA-392499
Mitotic Anaphase R-HSA-68882
Vpu mediated degradation of CD4 R-HSA-180534
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
CLEC7A (Dectin-1) signaling R-HSA-5607764
Axon guidance R-HSA-422475
Neutrophil degranulation R-HSA-6798695
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of AXIN R-HSA-4641257
Neddylation R-HSA-8951664
Signaling by ROBO receptors R-HSA-376176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Disorders of transmembrane transporters R-HSA-5619115
Signaling by NOTCH R-HSA-157118
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of amino acids and derivatives R-HSA-71291
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
S Phase R-HSA-69242
Cellular response to hypoxia R-HSA-1234174
p53-Dependent G1 DNA Damage Response R-HSA-69563
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TCR signaling R-HSA-202403
Cell Cycle R-HSA-1640170
Stabilization of p53 R-HSA-69541
C-type lectin receptors (CLRs) R-HSA-5621481
Deubiquitination R-HSA-5688426
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK1/MAPK3 signaling R-HSA-5684996
Post-translational protein modification R-HSA-597592
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Nuclear events mediated by NFE2L2 R-HSA-9759194
PTEN Regulation R-HSA-6807070
Metabolism of RNA R-HSA-8953854
Cell Cycle Checkpoints R-HSA-69620
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Mitotic Metaphase and Anaphase R-HSA-2555396
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Apoptosis R-HSA-109581
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Degradation of AXIN R-HSA-4641257
Hedgehog 'on' state R-HSA-5632684
ABC transporter disorders R-HSA-5619084
Signaling by Interleukins R-HSA-449147
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by NOTCH R-HSA-157118
Cellular response to hypoxia R-HSA-1234174
Signaling by NOTCH4 R-HSA-9013694
Regulation of RUNX2 expression and activity R-HSA-8939902
S Phase R-HSA-69242
UCH proteinases R-HSA-5689603
Transcriptional regulation by RUNX1 R-HSA-8878171
G1/S Transition R-HSA-69206
ABC-family proteins mediated transport R-HSA-382556
Disease R-HSA-1643685
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Independent DNA Damage Response R-HSA-69610
MAPK family signaling cascades R-HSA-5683057
FCERI mediated NF-kB activation R-HSA-2871837
Assembly of the pre-replicative complex R-HSA-68867
CLEC7A (Dectin-1) signaling R-HSA-5607764
ER-Phagosome pathway R-HSA-1236974
Innate Immune System R-HSA-168249
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular response to chemical stress R-HSA-9711123
Interleukin-1 family signaling R-HSA-446652
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Switching of origins to a post-replicative state R-HSA-69052
G1/S DNA Damage Checkpoints R-HSA-69615
Defective CFTR causes cystic fibrosis R-HSA-5678895
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
DNA Replication Pre-Initiation R-HSA-69002
Regulation of RUNX3 expression and activity R-HSA-8941858
Adaptive Immune System R-HSA-1280218
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cell Cycle, Mitotic R-HSA-69278
Metabolism of proteins R-HSA-392499
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX2 R-HSA-8878166
Disorders of transmembrane transporters R-HSA-5619115
Degradation of GLI1 by the proteasome R-HSA-5610780
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of Apoptosis R-HSA-169911
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of RAS by GAPs R-HSA-5658442
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Neutrophil degranulation R-HSA-6798695
Infectious disease R-HSA-5663205
Mitotic G2-G2/M phases R-HSA-453274
M Phase R-HSA-68886
Host Interactions of HIV factors R-HSA-162909
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Programmed Cell Death R-HSA-5357801
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Synthesis of DNA R-HSA-69239
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Developmental Biology R-HSA-1266738
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular responses to stimuli R-HSA-8953897
Downstream TCR signaling R-HSA-202424
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX3 R-HSA-8878159
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Hh mutants abrogate ligand secretion R-HSA-5387390
Class I MHC mediated antigen processing & presentation R-HSA-983169
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by Hedgehog R-HSA-5358351
Metabolism R-HSA-1430728
DNA Replication R-HSA-69306
Regulation of mitotic cell cycle R-HSA-453276
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog 'off' state R-HSA-5610787
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism of amino acids and derivatives R-HSA-71291
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of polyamines R-HSA-351202
Hh mutants are degraded by ERAD R-HSA-5362768
Nervous system development R-HSA-9675108
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interleukin-1 signaling R-HSA-9020702
Cellular responses to stress R-HSA-2262752
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Intracellular signaling by second messengers R-HSA-9006925
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of DVL R-HSA-4641258
Mitotic Anaphase R-HSA-68882
RNA Polymerase II Transcription R-HSA-73857
HIV Infection R-HSA-162906
Asymmetric localization of PCP proteins R-HSA-4608870
Cyclin E associated events during G1/S transition R-HSA-69202
PIP3 activates AKT signaling R-HSA-1257604
RAF/MAP kinase cascade R-HSA-5673001
TCF dependent signaling in response to WNT R-HSA-201681
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing-Cross presentation R-HSA-1236975
G2/M Transition R-HSA-69275
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Ub-specific processing proteases R-HSA-5689880
Activation of NF-kappaB in B cells R-HSA-1169091
Orc1 removal from chromatin R-HSA-68949
PCP/CE pathway R-HSA-4086400
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog ligand biogenesis R-HSA-5358346
Gene expression (Transcription) R-HSA-74160
Neddylation R-HSA-8951664
Signaling by WNT R-HSA-195721
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by ROBO receptors R-HSA-376176
Transport of small molecules R-HSA-382551
Separation of Sister Chromatids R-HSA-2467813
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
TCR signaling R-HSA-202403
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of PTEN stability and activity R-HSA-8948751
MAPK6/MAPK4 signaling R-HSA-5687128

Expression Atlas ENSG00000108344
NCBI gene (formerly Entrezgene) 5709
GeneCards 9560
HGNC Symbol HGNC:9560
MIM gene 617676
UniProtKB Gene Name O43242
WikiGene 5709
Gene: PSMC4
Ensembl ID : ENSG00000013275
Description: proteasome 26S subunit, ATPase 4
Gene Synonyms: MGC13687,MGC23214,MGC8570,MIP224,RPT3,S6,TBP-7,TBP7
5 APIs:
199 Possible Orthologues:

Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Generic Transcription Pathway R-HSA-212436
Interleukin-1 family signaling R-HSA-446652
Beta-catenin independent WNT signaling R-HSA-3858494
Cell Cycle, Mitotic R-HSA-69278
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transcriptional regulation by RUNX3 R-HSA-8878159
Vpu mediated degradation of CD4 R-HSA-180534
Switching of origins to a post-replicative state R-HSA-69052
Negative regulation of NOTCH4 signaling R-HSA-9604323
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Antigen processing-Cross presentation R-HSA-1236975
CLEC7A (Dectin-1) signaling R-HSA-5607764
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Adaptive Immune System R-HSA-1280218
Metabolism R-HSA-1430728
RAF/MAP kinase cascade R-HSA-5673001
Signaling by the B Cell Receptor (BCR) R-HSA-983705
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Immune System R-HSA-168256
Defective CFTR causes cystic fibrosis R-HSA-5678895
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Synthesis of DNA R-HSA-69239
Hedgehog ligand biogenesis R-HSA-5358346
G2/M Transition R-HSA-69275
MAPK family signaling cascades R-HSA-5683057
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI1 by the proteasome R-HSA-5610780
Orc1 removal from chromatin R-HSA-68949
ABC transporter disorders R-HSA-5619084
Signaling by WNT R-HSA-195721
Host Interactions of HIV factors R-HSA-162909
Generic Transcription Pathway R-HSA-212436
Ub-specific processing proteases R-HSA-5689880
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of polyamines R-HSA-351202
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
TCR signaling R-HSA-202403
Hh mutants abrogate ligand secretion R-HSA-5387390
Interleukin-1 signaling R-HSA-9020702
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by ROBO receptors R-HSA-376176
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of RUNX2 expression and activity R-HSA-8939902
Disease R-HSA-1643685
Metabolism of proteins R-HSA-392499
Transport of small molecules R-HSA-382551
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of Apoptosis R-HSA-169911
PTEN Regulation R-HSA-6807070
Intracellular signaling by second messengers R-HSA-9006925
Regulation of RAS by GAPs R-HSA-5658442
ABC-family proteins mediated transport R-HSA-382556
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by Interleukins R-HSA-449147
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Apoptosis R-HSA-109581
Degradation of GLI2 by the proteasome R-HSA-5610783
HIV Infection R-HSA-162906
p53-Independent DNA Damage Response R-HSA-69610
G2/M Checkpoints R-HSA-69481
Degradation of AXIN R-HSA-4641257
M Phase R-HSA-68886
Cellular response to chemical stress R-HSA-9711123
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cellular responses to stress R-HSA-2262752
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
PIP3 activates AKT signaling R-HSA-1257604
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of RNA R-HSA-8953854
Innate Immune System R-HSA-168249
p53-Dependent G1 DNA Damage Response R-HSA-69563
DNA Replication Pre-Initiation R-HSA-69002
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S DNA Damage Checkpoints R-HSA-69615
DNA Replication R-HSA-69306
Assembly of the pre-replicative complex R-HSA-68867
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Stabilization of p53 R-HSA-69541
MAPK1/MAPK3 signaling R-HSA-5684996
PCP/CE pathway R-HSA-4086400
Signal Transduction R-HSA-162582
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Nervous system development R-HSA-9675108
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Beta-catenin independent WNT signaling R-HSA-3858494
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle, Mitotic R-HSA-69278
Deubiquitination R-HSA-5688426
Signaling by NOTCH R-HSA-157118
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Vif-mediated degradation of APOBEC3G R-HSA-180585
TCF dependent signaling in response to WNT R-HSA-201681
Hedgehog 'on' state R-HSA-5632684
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
S Phase R-HSA-69242
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Separation of Sister Chromatids R-HSA-2467813
Nuclear events mediated by NFE2L2 R-HSA-9759194
Post-translational protein modification R-HSA-597592
Degradation of DVL R-HSA-4641258
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of PTEN stability and activity R-HSA-8948751
Disorders of transmembrane transporters R-HSA-5619115
Hedgehog 'off' state R-HSA-5610787
Cell Cycle Checkpoints R-HSA-69620
Cellular response to hypoxia R-HSA-1234174
UCH proteinases R-HSA-5689603
Programmed Cell Death R-HSA-5357801
Cellular responses to stimuli R-HSA-8953897
Cytokine Signaling in Immune system R-HSA-1280215
Hh mutants are degraded by ERAD R-HSA-5362768
Asymmetric localization of PCP proteins R-HSA-4608870
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX3 expression and activity R-HSA-8941858
Transcriptional regulation by RUNX1 R-HSA-8878171
Axon guidance R-HSA-422475
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
FCERI mediated NF-kB activation R-HSA-2871837
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic G1 phase and G1/S transition R-HSA-453279
Interleukin-1 family signaling R-HSA-446652
Signaling by Hedgehog R-HSA-5358351
Cell Cycle R-HSA-1640170
Regulation of mitotic cell cycle R-HSA-453276
Transcriptional regulation by RUNX2 R-HSA-8878166
KEAP1-NFE2L2 pathway R-HSA-9755511
Cyclin E associated events during G1/S transition R-HSA-69202
Neddylation R-HSA-8951664
Gene expression (Transcription) R-HSA-74160
Downstream TCR signaling R-HSA-202424
Activation of NF-kappaB in B cells R-HSA-1169091
RNA Polymerase II Transcription R-HSA-73857
ER-Phagosome pathway R-HSA-1236974
Mitotic Anaphase R-HSA-68882
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication Pre-Initiation R-HSA-69002
Regulation of PTEN stability and activity R-HSA-8948751
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transcriptional regulation by RUNX1 R-HSA-8878171
Stabilization of p53 R-HSA-69541
MAPK6/MAPK4 signaling R-HSA-5687128
Hedgehog 'off' state R-HSA-5610787
RAF/MAP kinase cascade R-HSA-5673001
Vpu mediated degradation of CD4 R-HSA-180534
Metabolism of amino acids and derivatives R-HSA-71291
Interleukin-1 family signaling R-HSA-446652
Axon guidance R-HSA-422475
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cellular responses to stimuli R-HSA-8953897
Separation of Sister Chromatids R-HSA-2467813
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic Anaphase R-HSA-68882
Switching of origins to a post-replicative state R-HSA-69052
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic Metaphase and Anaphase R-HSA-2555396
RNA Polymerase II Transcription R-HSA-73857
Degradation of beta-catenin by the destruction complex R-HSA-195253
Negative regulation of NOTCH4 signaling R-HSA-9604323
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of RUNX2 expression and activity R-HSA-8939902
Disorders of transmembrane transporters R-HSA-5619115
PTEN Regulation R-HSA-6807070
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by NOTCH R-HSA-157118
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Orc1 removal from chromatin R-HSA-68949
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Independent DNA Damage Response R-HSA-69610
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by Interleukins R-HSA-449147
Neddylation R-HSA-8951664
Metabolism of proteins R-HSA-392499
Infectious disease R-HSA-5663205
Innate Immune System R-HSA-168249
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
C-type lectin receptors (CLRs) R-HSA-5621481
Cell Cycle, Mitotic R-HSA-69278
Hedgehog 'on' state R-HSA-5632684
TCF dependent signaling in response to WNT R-HSA-201681
Cellular response to hypoxia R-HSA-1234174
G1/S Transition R-HSA-69206
Signaling by Hedgehog R-HSA-5358351
Developmental Biology R-HSA-1266738
Nuclear events mediated by NFE2L2 R-HSA-9759194
TCR signaling R-HSA-202403
S Phase R-HSA-69242
Defective CFTR causes cystic fibrosis R-HSA-5678895
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Gene expression (Transcription) R-HSA-74160
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Asymmetric localization of PCP proteins R-HSA-4608870
Activation of NF-kappaB in B cells R-HSA-1169091
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Generic Transcription Pathway R-HSA-212436
Antigen processing-Cross presentation R-HSA-1236975
MAPK1/MAPK3 signaling R-HSA-5684996
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by NOTCH4 R-HSA-9013694
Synthesis of DNA R-HSA-69239
Hh mutants abrogate ligand secretion R-HSA-5387390
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of mitotic cell cycle R-HSA-453276
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
ER-Phagosome pathway R-HSA-1236974
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of polyamines R-HSA-351202
Interleukin-1 signaling R-HSA-9020702
Beta-catenin independent WNT signaling R-HSA-3858494
Assembly of the pre-replicative complex R-HSA-68867
Degradation of DVL R-HSA-4641258
Regulation of RUNX3 expression and activity R-HSA-8941858
Cyclin E associated events during G1/S transition R-HSA-69202
Transport of small molecules R-HSA-382551
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
G2/M Transition R-HSA-69275
Deubiquitination R-HSA-5688426
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of AXIN R-HSA-4641257
PIP3 activates AKT signaling R-HSA-1257604
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
ABC transporter disorders R-HSA-5619084
Adaptive Immune System R-HSA-1280218
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK family signaling cascades R-HSA-5683057
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
DNA Replication R-HSA-69306
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PCP/CE pathway R-HSA-4086400
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of RNA R-HSA-8953854
HIV Infection R-HSA-162906
UCH proteinases R-HSA-5689603
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular responses to stress R-HSA-2262752
Nervous system development R-HSA-9675108
Ub-specific processing proteases R-HSA-5689880
Degradation of GLI2 by the proteasome R-HSA-5610783
Downstream TCR signaling R-HSA-202424
G1/S DNA Damage Checkpoints R-HSA-69615
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular response to chemical stress R-HSA-9711123
Cell Cycle R-HSA-1640170
Metabolism R-HSA-1430728
Cell Cycle Checkpoints R-HSA-69620
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of RAS by GAPs R-HSA-5658442
Post-translational protein modification R-HSA-597592
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by WNT R-HSA-195721
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Programmed Cell Death R-HSA-5357801
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Vif-mediated degradation of APOBEC3G R-HSA-180585
ABC-family proteins mediated transport R-HSA-382556
Transcriptional regulation by RUNX3 R-HSA-8878159
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of Apoptosis R-HSA-169911
Host Interactions of HIV factors R-HSA-162909
G2/M Checkpoints R-HSA-69481
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
M Phase R-HSA-68886
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
Signaling by ROBO receptors R-HSA-376176
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Apoptosis R-HSA-109581
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by ROBO receptors R-HSA-376176
Ub-specific processing proteases R-HSA-5689880
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Axon guidance R-HSA-422475
Innate Immune System R-HSA-168249
Neddylation R-HSA-8951664
Infectious disease R-HSA-5663205
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog 'off' state R-HSA-5610787
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of RNA R-HSA-8953854
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX2 R-HSA-8878166
Nuclear events mediated by NFE2L2 R-HSA-9759194
Downstream TCR signaling R-HSA-202424
DNA Replication Pre-Initiation R-HSA-69002
Degradation of GLI1 by the proteasome R-HSA-5610780
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disease R-HSA-1643685
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Beta-catenin independent WNT signaling R-HSA-3858494
Class I MHC mediated antigen processing & presentation R-HSA-983169
Apoptosis R-HSA-109581
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of amino acids and derivatives R-HSA-71291
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular responses to stimuli R-HSA-8953897
Antigen processing-Cross presentation R-HSA-1236975
Regulation of PTEN stability and activity R-HSA-8948751
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G2/M Checkpoints R-HSA-69481
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCF dependent signaling in response to WNT R-HSA-201681
Cytokine Signaling in Immune system R-HSA-1280215
UCH proteinases R-HSA-5689603
Cellular response to hypoxia R-HSA-1234174
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Metabolism of polyamines R-HSA-351202
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
MAPK6/MAPK4 signaling R-HSA-5687128
Gene expression (Transcription) R-HSA-74160
TCR signaling R-HSA-202403
Mitotic G1 phase and G1/S transition R-HSA-453279
Cellular responses to stress R-HSA-2262752
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cyclin E associated events during G1/S transition R-HSA-69202
PIP3 activates AKT signaling R-HSA-1257604
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of AXIN R-HSA-4641257
Degradation of GLI2 by the proteasome R-HSA-5610783
PCP/CE pathway R-HSA-4086400
MAPK1/MAPK3 signaling R-HSA-5684996
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Immune System R-HSA-168256
Negative regulation of NOTCH4 signaling R-HSA-9604323
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by NOTCH4 R-HSA-9013694
ABC-family proteins mediated transport R-HSA-382556
Degradation of DVL R-HSA-4641258
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of Apoptosis R-HSA-169911
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of RUNX3 expression and activity R-HSA-8941858
Cellular response to chemical stress R-HSA-9711123
RNA Polymerase II Transcription R-HSA-73857
Post-translational protein modification R-HSA-597592
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S Transition R-HSA-69206
Regulation of RAS by GAPs R-HSA-5658442
Signaling by WNT R-HSA-195721
Signaling by NOTCH R-HSA-157118
Cell Cycle Checkpoints R-HSA-69620
Separation of Sister Chromatids R-HSA-2467813
Vpu mediated degradation of CD4 R-HSA-180534
Assembly of the pre-replicative complex R-HSA-68867
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hedgehog ligand biogenesis R-HSA-5358346
Signal Transduction R-HSA-162582
ER-Phagosome pathway R-HSA-1236974
Interleukin-1 signaling R-HSA-9020702
Mitotic Anaphase R-HSA-68882
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Intracellular signaling by second messengers R-HSA-9006925
p53-Independent DNA Damage Response R-HSA-69610
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
ABC transporter disorders R-HSA-5619084
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Mitotic G2-G2/M phases R-HSA-453274
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Nervous system development R-HSA-9675108
Hedgehog 'on' state R-HSA-5632684
Signaling by Interleukins R-HSA-449147
C-type lectin receptors (CLRs) R-HSA-5621481
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Interleukin-1 family signaling R-HSA-446652
Transport of small molecules R-HSA-382551
Generic Transcription Pathway R-HSA-212436
Adaptive Immune System R-HSA-1280218
Regulation of mitotic cell cycle R-HSA-453276
Switching of origins to a post-replicative state R-HSA-69052
Cell Cycle, Mitotic R-HSA-69278
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
DNA Replication R-HSA-69306
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Defective CFTR causes cystic fibrosis R-HSA-5678895
Disorders of transmembrane transporters R-HSA-5619115
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX1 R-HSA-8878171
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism R-HSA-1430728
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
PTEN Regulation R-HSA-6807070
HIV Infection R-HSA-162906
Deubiquitination R-HSA-5688426
Orc1 removal from chromatin R-HSA-68949
FCERI mediated NF-kB activation R-HSA-2871837
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G2/M Transition R-HSA-69275
Mitotic Metaphase and Anaphase R-HSA-2555396
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by Hedgehog R-HSA-5358351
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle R-HSA-1640170
Regulation of RUNX2 expression and activity R-HSA-8939902
Hh mutants are degraded by ERAD R-HSA-5362768
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Degradation of beta-catenin by the destruction complex R-HSA-195253
Developmental Biology R-HSA-1266738
Hh mutants abrogate ligand secretion R-HSA-5387390
Host Interactions of HIV factors R-HSA-162909
S Phase R-HSA-69242
CLEC7A (Dectin-1) signaling R-HSA-5607764
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Vif-mediated degradation of APOBEC3G R-HSA-180585
MAPK family signaling cascades R-HSA-5683057
M Phase R-HSA-68886
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G2/M Transition R-HSA-69275
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Antigen processing-Cross presentation R-HSA-1236975
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transport of small molecules R-HSA-382551
G2/M Checkpoints R-HSA-69481
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
PTEN Regulation R-HSA-6807070
Metabolism of polyamines R-HSA-351202
MAPK1/MAPK3 signaling R-HSA-5684996
Infectious disease R-HSA-5663205
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Degradation of GLI1 by the proteasome R-HSA-5610780
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of Apoptosis R-HSA-169911
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of RUNX2 expression and activity R-HSA-8939902
Cell Cycle, Mitotic R-HSA-69278
Apoptosis R-HSA-109581
Stabilization of p53 R-HSA-69541
Neddylation R-HSA-8951664
CLEC7A (Dectin-1) signaling R-HSA-5607764
NIK-->noncanonical NF-kB signaling R-HSA-5676590
ER-Phagosome pathway R-HSA-1236974
Signaling by ROBO receptors R-HSA-376176
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCR signaling R-HSA-202403
Downstream TCR signaling R-HSA-202424
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transcriptional regulation by RUNX3 R-HSA-8878159
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of RNA R-HSA-8953854
Signaling by Interleukins R-HSA-449147
Signaling by NOTCH R-HSA-157118
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of DVL R-HSA-4641258
Cytokine Signaling in Immune system R-HSA-1280215
Cellular response to hypoxia R-HSA-1234174
ABC-family proteins mediated transport R-HSA-382556
Programmed Cell Death R-HSA-5357801
PIP3 activates AKT signaling R-HSA-1257604
DNA Replication Pre-Initiation R-HSA-69002
Signaling by Hedgehog R-HSA-5358351
MAPK family signaling cascades R-HSA-5683057
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by WNT R-HSA-195721
Signaling by NOTCH4 R-HSA-9013694
HIV Infection R-HSA-162906
Disorders of transmembrane transporters R-HSA-5619115
Vpu mediated degradation of CD4 R-HSA-180534
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog 'on' state R-HSA-5632684
Deubiquitination R-HSA-5688426
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PCP/CE pathway R-HSA-4086400
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G2-G2/M phases R-HSA-453274
Cellular response to chemical stress R-HSA-9711123
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Adaptive Immune System R-HSA-1280218
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX1 R-HSA-8878171
Synthesis of DNA R-HSA-69239
Cellular responses to stimuli R-HSA-8953897
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TCF dependent signaling in response to WNT R-HSA-201681
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular responses to stress R-HSA-2262752
Metabolism R-HSA-1430728
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of amino acids and derivatives R-HSA-71291
Ub-specific processing proteases R-HSA-5689880
Defective CFTR causes cystic fibrosis R-HSA-5678895
Mitotic G1 phase and G1/S transition R-HSA-453279
Post-translational protein modification R-HSA-597592
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Disease R-HSA-1643685
Orc1 removal from chromatin R-HSA-68949
S Phase R-HSA-69242
Cyclin E associated events during G1/S transition R-HSA-69202
Signal Transduction R-HSA-162582
Interleukin-1 family signaling R-HSA-446652
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RNA Polymerase II Transcription R-HSA-73857
ABC transporter disorders R-HSA-5619084
Regulation of RUNX3 expression and activity R-HSA-8941858
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S Transition R-HSA-69206
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX2 R-HSA-8878166
Negative regulation of NOTCH4 signaling R-HSA-9604323
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Intracellular signaling by second messengers R-HSA-9006925
Host Interactions of HIV factors R-HSA-162909
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
C-type lectin receptors (CLRs) R-HSA-5621481
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of AXIN R-HSA-4641257
Innate Immune System R-HSA-168249
G1/S DNA Damage Checkpoints R-HSA-69615
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Immune System R-HSA-168256
DNA Replication R-HSA-69306
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Nervous system development R-HSA-9675108
Generic Transcription Pathway R-HSA-212436
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Gene expression (Transcription) R-HSA-74160
Metabolism of proteins R-HSA-392499
Hedgehog 'off' state R-HSA-5610787
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of mitotic cell cycle R-HSA-453276
p53-Dependent G1 DNA Damage Response R-HSA-69563
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic Metaphase and Anaphase R-HSA-2555396
Axon guidance R-HSA-422475
Regulation of RAS by GAPs R-HSA-5658442
Activation of NF-kappaB in B cells R-HSA-1169091
Interleukin-1 signaling R-HSA-9020702
Switching of origins to a post-replicative state R-HSA-69052
p53-Independent DNA Damage Response R-HSA-69610
Vif-mediated degradation of APOBEC3G R-HSA-180585
FCERI mediated NF-kB activation R-HSA-2871837
Assembly of the pre-replicative complex R-HSA-68867
RAF/MAP kinase cascade R-HSA-5673001
M Phase R-HSA-68886
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cell Cycle Checkpoints R-HSA-69620
Regulation of PTEN stability and activity R-HSA-8948751
UCH proteinases R-HSA-5689603
Cell Cycle R-HSA-1640170
Class I MHC mediated antigen processing & presentation R-HSA-983169
Disease R-HSA-1643685
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Downstream TCR signaling R-HSA-202424
UCH proteinases R-HSA-5689603
Cell Cycle Checkpoints R-HSA-69620
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TCR signaling R-HSA-202403
Beta-catenin independent WNT signaling R-HSA-3858494
Apoptosis R-HSA-109581
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by the B Cell Receptor (BCR) R-HSA-983705
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Independent DNA Damage Response R-HSA-69610
Switching of origins to a post-replicative state R-HSA-69052
G2/M Checkpoints R-HSA-69481
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of GLI1 by the proteasome R-HSA-5610780
Host Interactions of HIV factors R-HSA-162909
Assembly of the pre-replicative complex R-HSA-68867
Developmental Biology R-HSA-1266738
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
G1/S Transition R-HSA-69206
Innate Immune System R-HSA-168249
Stabilization of p53 R-HSA-69541
RAF/MAP kinase cascade R-HSA-5673001
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation by RUNX1 R-HSA-8878171
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Defective CFTR causes cystic fibrosis R-HSA-5678895
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 family signaling R-HSA-446652
ER-Phagosome pathway R-HSA-1236974
Degradation of AXIN R-HSA-4641257
Mitotic Anaphase R-HSA-68882
ABC-family proteins mediated transport R-HSA-382556
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
HIV Infection R-HSA-162906
Signaling by Interleukins R-HSA-449147
Separation of Sister Chromatids R-HSA-2467813
Cytokine Signaling in Immune system R-HSA-1280215
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cellular response to chemical stress R-HSA-9711123
DNA Replication Pre-Initiation R-HSA-69002
Metabolism of amino acids and derivatives R-HSA-71291
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Immune System R-HSA-168256
Transport of small molecules R-HSA-382551
DNA Replication R-HSA-69306
Intracellular signaling by second messengers R-HSA-9006925
Mitotic G2-G2/M phases R-HSA-453274
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of Apoptosis R-HSA-169911
Degradation of GLI2 by the proteasome R-HSA-5610783
TCF dependent signaling in response to WNT R-HSA-201681
Gene expression (Transcription) R-HSA-74160
G1/S DNA Damage Checkpoints R-HSA-69615
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by NOTCH R-HSA-157118
Signal Transduction R-HSA-162582
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Neddylation R-HSA-8951664
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular responses to stress R-HSA-2262752
Axon guidance R-HSA-422475
Signaling by Hedgehog R-HSA-5358351
Signaling by WNT R-HSA-195721
CLEC7A (Dectin-1) signaling R-HSA-5607764
Deubiquitination R-HSA-5688426
Cyclin E associated events during G1/S transition R-HSA-69202
S Phase R-HSA-69242
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Vif-mediated degradation of APOBEC3G R-HSA-180585
MAPK1/MAPK3 signaling R-HSA-5684996
Ub-specific processing proteases R-HSA-5689880
Hh mutants are degraded by ERAD R-HSA-5362768
Cell Cycle R-HSA-1640170
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Post-translational protein modification R-HSA-597592
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Generic Transcription Pathway R-HSA-212436
Class I MHC mediated antigen processing & presentation R-HSA-983169
PCP/CE pathway R-HSA-4086400
Orc1 removal from chromatin R-HSA-68949
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'on' state R-HSA-5632684
ABC transporter disorders R-HSA-5619084
Metabolism of proteins R-HSA-392499
M Phase R-HSA-68886
PTEN Regulation R-HSA-6807070
Interleukin-1 signaling R-HSA-9020702
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Vpu mediated degradation of CD4 R-HSA-180534
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cellular responses to stimuli R-HSA-8953897
Regulation of PTEN stability and activity R-HSA-8948751
C-type lectin receptors (CLRs) R-HSA-5621481
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of RNA R-HSA-8953854
Nuclear events mediated by NFE2L2 R-HSA-9759194
Activation of NF-kappaB in B cells R-HSA-1169091
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism of polyamines R-HSA-351202
Antigen processing-Cross presentation R-HSA-1236975
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RNA Polymerase II Transcription R-HSA-73857
Hedgehog 'off' state R-HSA-5610787
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
Signaling by ROBO receptors R-HSA-376176
MAPK family signaling cascades R-HSA-5683057
Signaling by NOTCH4 R-HSA-9013694
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RAS by GAPs R-HSA-5658442
Cell Cycle, Mitotic R-HSA-69278
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Negative regulation of NOTCH4 signaling R-HSA-9604323
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic Metaphase and Anaphase R-HSA-2555396
Adaptive Immune System R-HSA-1280218
Transcriptional regulation by RUNX3 R-HSA-8878159
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of beta-catenin by the destruction complex R-HSA-195253
Programmed Cell Death R-HSA-5357801
Disorders of transmembrane transporters R-HSA-5619115
Synthesis of DNA R-HSA-69239
G2/M Transition R-HSA-69275
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of DVL R-HSA-4641258
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism R-HSA-1430728
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Disorders of transmembrane transporters R-HSA-5619115
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism R-HSA-1430728
TCF dependent signaling in response to WNT R-HSA-201681
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular response to hypoxia R-HSA-1234174
PTEN Regulation R-HSA-6807070
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX2 R-HSA-8878166
Innate Immune System R-HSA-168249
Downstream TCR signaling R-HSA-202424
Antigen processing-Cross presentation R-HSA-1236975
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Mitotic G2-G2/M phases R-HSA-453274
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of DVL R-HSA-4641258
Gene expression (Transcription) R-HSA-74160
Metabolism of RNA R-HSA-8953854
ABC-family proteins mediated transport R-HSA-382556
ABC transporter disorders R-HSA-5619084
Regulation of PTEN stability and activity R-HSA-8948751
PCP/CE pathway R-HSA-4086400
Metabolism of proteins R-HSA-392499
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Immune System R-HSA-168256
Degradation of AXIN R-HSA-4641257
M Phase R-HSA-68886
Regulation of Apoptosis R-HSA-169911
Signaling by NOTCH4 R-HSA-9013694
RAF/MAP kinase cascade R-HSA-5673001
DNA Replication Pre-Initiation R-HSA-69002
Programmed Cell Death R-HSA-5357801
Host Interactions of HIV factors R-HSA-162909
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
DNA Replication R-HSA-69306
Vpu mediated degradation of CD4 R-HSA-180534
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
G2/M Transition R-HSA-69275
Intracellular signaling by second messengers R-HSA-9006925
Regulation of RAS by GAPs R-HSA-5658442
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX3 R-HSA-8878159
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of RUNX3 expression and activity R-HSA-8941858
Nuclear events mediated by NFE2L2 R-HSA-9759194
Apoptosis R-HSA-109581
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Developmental Biology R-HSA-1266738
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Defective CFTR causes cystic fibrosis R-HSA-5678895
PIP3 activates AKT signaling R-HSA-1257604
Signaling by WNT R-HSA-195721
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle, Mitotic R-HSA-69278
Hedgehog 'off' state R-HSA-5610787
Vif-mediated degradation of APOBEC3G R-HSA-180585
Asymmetric localization of PCP proteins R-HSA-4608870
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI2 by the proteasome R-HSA-5610783
Neddylation R-HSA-8951664
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX2 expression and activity R-HSA-8939902
Mitotic Metaphase and Anaphase R-HSA-2555396
CLEC7A (Dectin-1) signaling R-HSA-5607764
UCH proteinases R-HSA-5689603
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
KEAP1-NFE2L2 pathway R-HSA-9755511
Stabilization of p53 R-HSA-69541
Signal Transduction R-HSA-162582
Metabolism of polyamines R-HSA-351202
TCR signaling R-HSA-202403
Signaling by ROBO receptors R-HSA-376176
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stimuli R-HSA-8953897
Assembly of the pre-replicative complex R-HSA-68867
Orc1 removal from chromatin R-HSA-68949
Disease R-HSA-1643685
Interleukin-1 signaling R-HSA-9020702
RNA Polymerase II Transcription R-HSA-73857
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hh mutants abrogate ligand secretion R-HSA-5387390
FCERI mediated NF-kB activation R-HSA-2871837
Activation of NF-kappaB in B cells R-HSA-1169091
HIV Infection R-HSA-162906
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Hedgehog R-HSA-5358351
Signaling by Interleukins R-HSA-449147
Post-translational protein modification R-HSA-597592
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S Transition R-HSA-69206
p53-Independent DNA Damage Response R-HSA-69610
Ub-specific processing proteases R-HSA-5689880
Synthesis of DNA R-HSA-69239
Mitotic Anaphase R-HSA-68882
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to chemical stress R-HSA-9711123
MAPK family signaling cascades R-HSA-5683057
S Phase R-HSA-69242
Switching of origins to a post-replicative state R-HSA-69052
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Adaptive Immune System R-HSA-1280218
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transport of small molecules R-HSA-382551
Signaling by NOTCH R-HSA-157118
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Infectious disease R-HSA-5663205
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic G1 phase and G1/S transition R-HSA-453279
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cyclin E associated events during G1/S transition R-HSA-69202
Hedgehog 'on' state R-HSA-5632684
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle Checkpoints R-HSA-69620
MAPK6/MAPK4 signaling R-HSA-5687128
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stress R-HSA-2262752
ER-Phagosome pathway R-HSA-1236974
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
p53-Dependent G1 DNA Damage Response R-HSA-69563
Deubiquitination R-HSA-5688426
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hedgehog ligand biogenesis R-HSA-5358346
G2/M Checkpoints R-HSA-69481
Cell Cycle R-HSA-1640170
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Metabolism of amino acids and derivatives R-HSA-71291
Separation of Sister Chromatids R-HSA-2467813
Class I MHC mediated antigen processing & presentation R-HSA-983169
Assembly of the pre-replicative complex R-HSA-68867
UCH proteinases R-HSA-5689603
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Mitotic G2-G2/M phases R-HSA-453274
PTEN Regulation R-HSA-6807070
Hedgehog 'on' state R-HSA-5632684
Cellular responses to stimuli R-HSA-8953897
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Programmed Cell Death R-HSA-5357801
Neddylation R-HSA-8951664
Mitotic G1 phase and G1/S transition R-HSA-453279
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hh mutants abrogate ligand secretion R-HSA-5387390
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
DNA Replication Pre-Initiation R-HSA-69002
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
PCP/CE pathway R-HSA-4086400
Signaling by Interleukins R-HSA-449147
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of DVL R-HSA-4641258
Developmental Biology R-HSA-1266738
Host Interactions of HIV factors R-HSA-162909
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Intracellular signaling by second messengers R-HSA-9006925
Axon guidance R-HSA-422475
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Metabolism R-HSA-1430728
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-1 family signaling R-HSA-446652
Apoptosis R-HSA-109581
Signaling by WNT R-HSA-195721
Degradation of GLI1 by the proteasome R-HSA-5610780
Hedgehog 'off' state R-HSA-5610787
Innate Immune System R-HSA-168249
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Checkpoints R-HSA-69481
Metabolism of amino acids and derivatives R-HSA-71291
DNA Replication R-HSA-69306
Mitotic Metaphase and Anaphase R-HSA-2555396
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
Transcriptional regulation by RUNX2 R-HSA-8878166
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Interleukin-1 signaling R-HSA-9020702
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of proteins R-HSA-392499
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of expression of SLITs and ROBOs R-HSA-9010553
G1/S Transition R-HSA-69206
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog ligand biogenesis R-HSA-5358346
FCERI mediated NF-kB activation R-HSA-2871837
HIV Infection R-HSA-162906
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Infectious disease R-HSA-5663205
Cellular responses to stress R-HSA-2262752
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Separation of Sister Chromatids R-HSA-2467813
Post-translational protein modification R-HSA-597592
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
RAF/MAP kinase cascade R-HSA-5673001
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Orc1 removal from chromatin R-HSA-68949
Adaptive Immune System R-HSA-1280218
Regulation of RAS by GAPs R-HSA-5658442
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular response to hypoxia R-HSA-1234174
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Transcriptional regulation by RUNX3 R-HSA-8878159
Immune System R-HSA-168256
Transcriptional regulation by RUNX1 R-HSA-8878171
Gene expression (Transcription) R-HSA-74160
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Nuclear events mediated by NFE2L2 R-HSA-9759194
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of Apoptosis R-HSA-169911
Signaling by Hedgehog R-HSA-5358351
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Synthesis of DNA R-HSA-69239
Degradation of AXIN R-HSA-4641257
Vpu mediated degradation of CD4 R-HSA-180534
MAPK family signaling cascades R-HSA-5683057
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
S Phase R-HSA-69242
M Phase R-HSA-68886
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic Anaphase R-HSA-68882
Regulation of RUNX3 expression and activity R-HSA-8941858
Disorders of transmembrane transporters R-HSA-5619115
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
CLEC7A (Dectin-1) signaling R-HSA-5607764
Asymmetric localization of PCP proteins R-HSA-4608870
Cell Cycle R-HSA-1640170
Downstream TCR signaling R-HSA-202424
Hh mutants are degraded by ERAD R-HSA-5362768
Cell Cycle, Mitotic R-HSA-69278
Switching of origins to a post-replicative state R-HSA-69052
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of GLI2 by the proteasome R-HSA-5610783
Stabilization of p53 R-HSA-69541
Signaling by NOTCH R-HSA-157118
MAPK6/MAPK4 signaling R-HSA-5687128
C-type lectin receptors (CLRs) R-HSA-5621481
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle Checkpoints R-HSA-69620
Regulation of mitotic cell cycle R-HSA-453276
Deubiquitination R-HSA-5688426
Defective CFTR causes cystic fibrosis R-HSA-5678895
TCR signaling R-HSA-202403
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cellular response to chemical stress R-HSA-9711123
G2/M Transition R-HSA-69275
Signaling by ROBO receptors R-HSA-376176
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
ABC-family proteins mediated transport R-HSA-382556
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH4 R-HSA-9013694
Negative regulation of NOTCH4 signaling R-HSA-9604323
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK1/MAPK3 signaling R-HSA-5684996
KEAP1-NFE2L2 pathway R-HSA-9755511
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of RUNX2 expression and activity R-HSA-8939902
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Ub-specific processing proteases R-HSA-5689880
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
ABC transporter disorders R-HSA-5619084
G1/S DNA Damage Checkpoints R-HSA-69615
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signal Transduction R-HSA-162582
Metabolism of polyamines R-HSA-351202
p53-Independent DNA Damage Response R-HSA-69610
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Developmental Biology R-HSA-1266738
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle Checkpoints R-HSA-69620
Transcriptional regulation by RUNX2 R-HSA-8878166
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PTEN Regulation R-HSA-6807070
Regulation of RUNX2 expression and activity R-HSA-8939902
Disease R-HSA-1643685
Deubiquitination R-HSA-5688426
Metabolism of polyamines R-HSA-351202
Metabolism R-HSA-1430728
Antigen processing-Cross presentation R-HSA-1236975
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cellular responses to stress R-HSA-2262752
CLEC7A (Dectin-1) signaling R-HSA-5607764
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Interleukin-1 signaling R-HSA-9020702
Infectious disease R-HSA-5663205
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signal Transduction R-HSA-162582
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
ABC-family proteins mediated transport R-HSA-382556
Separation of Sister Chromatids R-HSA-2467813
Regulation of Apoptosis R-HSA-169911
Generic Transcription Pathway R-HSA-212436
Cell Cycle, Mitotic R-HSA-69278
MAPK6/MAPK4 signaling R-HSA-5687128
UCH proteinases R-HSA-5689603
p53-Independent DNA Damage Response R-HSA-69610
Activation of NF-kappaB in B cells R-HSA-1169091
Neddylation R-HSA-8951664
Metabolism of amino acids and derivatives R-HSA-71291
G1/S Transition R-HSA-69206
Signaling by the B Cell Receptor (BCR) R-HSA-983705
S Phase R-HSA-69242
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of proteins R-HSA-392499
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Stabilization of p53 R-HSA-69541
Signaling by Interleukins R-HSA-449147
G1/S DNA Damage Checkpoints R-HSA-69615
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vif-mediated degradation of APOBEC3G R-HSA-180585
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Innate Immune System R-HSA-168249
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
DNA Replication Pre-Initiation R-HSA-69002
FCERI mediated NF-kB activation R-HSA-2871837
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Mitotic G2-G2/M phases R-HSA-453274
Defective CFTR causes cystic fibrosis R-HSA-5678895
M Phase R-HSA-68886
HIV Infection R-HSA-162906
Apoptosis R-HSA-109581
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Transcriptional regulation by RUNX3 R-HSA-8878159
ABC transporter disorders R-HSA-5619084
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog ligand biogenesis R-HSA-5358346
Adaptive Immune System R-HSA-1280218
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by Hedgehog R-HSA-5358351
Orc1 removal from chromatin R-HSA-68949
ER-Phagosome pathway R-HSA-1236974
RNA Polymerase II Transcription R-HSA-73857
Degradation of AXIN R-HSA-4641257
Assembly of the pre-replicative complex R-HSA-68867
Cellular response to hypoxia R-HSA-1234174
Switching of origins to a post-replicative state R-HSA-69052
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of beta-catenin by the destruction complex R-HSA-195253
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Interleukin-1 family signaling R-HSA-446652
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Mitotic Anaphase R-HSA-68882
Cellular responses to stimuli R-HSA-8953897
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Intracellular signaling by second messengers R-HSA-9006925
Cellular response to chemical stress R-HSA-9711123
Cyclin E associated events during G1/S transition R-HSA-69202
Vpu mediated degradation of CD4 R-HSA-180534
Host Interactions of HIV factors R-HSA-162909
Hh mutants abrogate ligand secretion R-HSA-5387390
MAPK1/MAPK3 signaling R-HSA-5684996
G2/M Transition R-HSA-69275
PIP3 activates AKT signaling R-HSA-1257604
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of mitotic cell cycle R-HSA-453276
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
RAF/MAP kinase cascade R-HSA-5673001
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
TCR signaling R-HSA-202403
Post-translational protein modification R-HSA-597592
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'off' state R-HSA-5610787
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of RAS by GAPs R-HSA-5658442
Ub-specific processing proteases R-HSA-5689880
KEAP1-NFE2L2 pathway R-HSA-9755511
Synthesis of DNA R-HSA-69239
G2/M Checkpoints R-HSA-69481
Signaling by NOTCH R-HSA-157118
Nervous system development R-HSA-9675108
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Negative regulation of NOTCH4 signaling R-HSA-9604323
C-type lectin receptors (CLRs) R-HSA-5621481
Downstream TCR signaling R-HSA-202424
Gene expression (Transcription) R-HSA-74160
Hedgehog 'on' state R-HSA-5632684
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by WNT R-HSA-195721
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Axon guidance R-HSA-422475
Nuclear events mediated by NFE2L2 R-HSA-9759194
Transport of small molecules R-HSA-382551
Degradation of GLI1 by the proteasome R-HSA-5610780
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cell Cycle R-HSA-1640170
Disorders of transmembrane transporters R-HSA-5619115
Hh mutants are degraded by ERAD R-HSA-5362768
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by ROBO receptors R-HSA-376176
PCP/CE pathway R-HSA-4086400
Signaling by NOTCH4 R-HSA-9013694
Regulation of RUNX3 expression and activity R-HSA-8941858
MAPK family signaling cascades R-HSA-5683057
DNA Replication R-HSA-69306
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Transcriptional regulation by RUNX1 R-HSA-8878171
Asymmetric localization of PCP proteins R-HSA-4608870
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of RNA R-HSA-8953854
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of DVL R-HSA-4641258
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Generic Transcription Pathway R-HSA-212436
HIV Infection R-HSA-162906
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
Transcriptional regulation by RUNX1 R-HSA-8878171
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Vpu mediated degradation of CD4 R-HSA-180534
Signal Transduction R-HSA-162582
Metabolism of amino acids and derivatives R-HSA-71291
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of mitotic cell cycle R-HSA-453276
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of AXIN R-HSA-4641257
Ub-specific processing proteases R-HSA-5689880
Nervous system development R-HSA-9675108
Metabolism R-HSA-1430728
Transcriptional regulation by RUNX2 R-HSA-8878166
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Asymmetric localization of PCP proteins R-HSA-4608870
Immune System R-HSA-168256
PIP3 activates AKT signaling R-HSA-1257604
Degradation of DVL R-HSA-4641258
Cell Cycle R-HSA-1640170
MAPK family signaling cascades R-HSA-5683057
G2/M Transition R-HSA-69275
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Negative regulation of NOTCH4 signaling R-HSA-9604323
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
PCP/CE pathway R-HSA-4086400
Cellular response to hypoxia R-HSA-1234174
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCR signaling R-HSA-202403
Cell Cycle Checkpoints R-HSA-69620
Degradation of GLI2 by the proteasome R-HSA-5610783
Mitotic Metaphase and Anaphase R-HSA-2555396
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of RNA R-HSA-8953854
ABC-family proteins mediated transport R-HSA-382556
Axon guidance R-HSA-422475
Host Interactions of HIV factors R-HSA-162909
Deubiquitination R-HSA-5688426
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
p53-Dependent G1 DNA Damage Response R-HSA-69563
FCERI mediated NF-kB activation R-HSA-2871837
Synthesis of DNA R-HSA-69239
Adaptive Immune System R-HSA-1280218
Gene expression (Transcription) R-HSA-74160
UCH proteinases R-HSA-5689603
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Interleukin-1 signaling R-HSA-9020702
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by ROBO receptors R-HSA-376176
Signaling by NOTCH4 R-HSA-9013694
Interleukin-1 family signaling R-HSA-446652
Cellular responses to stress R-HSA-2262752
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
M Phase R-HSA-68886
Stabilization of p53 R-HSA-69541
KEAP1-NFE2L2 pathway R-HSA-9755511
Antigen processing-Cross presentation R-HSA-1236975
Signaling by Interleukins R-HSA-449147
G1/S Transition R-HSA-69206
Apoptosis R-HSA-109581
Mitotic Anaphase R-HSA-68882
Degradation of beta-catenin by the destruction complex R-HSA-195253
Metabolism of polyamines R-HSA-351202
TCF dependent signaling in response to WNT R-HSA-201681
Assembly of the pre-replicative complex R-HSA-68867
Developmental Biology R-HSA-1266738
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX3 R-HSA-8878159
Downstream TCR signaling R-HSA-202424
ER-Phagosome pathway R-HSA-1236974
MAPK1/MAPK3 signaling R-HSA-5684996
Infectious disease R-HSA-5663205
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G2-G2/M phases R-HSA-453274
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hh mutants abrogate ligand secretion R-HSA-5387390
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hedgehog 'on' state R-HSA-5632684
Mitotic G1 phase and G1/S transition R-HSA-453279
Cellular response to chemical stress R-HSA-9711123
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cytokine Signaling in Immune system R-HSA-1280215
Intracellular signaling by second messengers R-HSA-9006925
RAF/MAP kinase cascade R-HSA-5673001
Disease R-HSA-1643685
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Innate Immune System R-HSA-168249
Separation of Sister Chromatids R-HSA-2467813
RNA Polymerase II Transcription R-HSA-73857
MAPK6/MAPK4 signaling R-HSA-5687128
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by WNT R-HSA-195721
NIK-->noncanonical NF-kB signaling R-HSA-5676590
G2/M Checkpoints R-HSA-69481
Transport of small molecules R-HSA-382551
Hedgehog 'off' state R-HSA-5610787
DNA Replication R-HSA-69306
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of Apoptosis R-HSA-169911
PTEN Regulation R-HSA-6807070
Signaling by NOTCH R-HSA-157118
Defective CFTR causes cystic fibrosis R-HSA-5678895
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cyclin E associated events during G1/S transition R-HSA-69202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Neddylation R-HSA-8951664
Cellular responses to stimuli R-HSA-8953897
Signaling by Hedgehog R-HSA-5358351
Regulation of RUNX2 expression and activity R-HSA-8939902
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Vif-mediated degradation of APOBEC3G R-HSA-180585
Post-translational protein modification R-HSA-597592
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
S Phase R-HSA-69242
Orc1 removal from chromatin R-HSA-68949
p53-Independent DNA Damage Response R-HSA-69610
Regulation of PTEN stability and activity R-HSA-8948751
DNA Replication Pre-Initiation R-HSA-69002
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of RAS by GAPs R-HSA-5658442
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hh mutants are degraded by ERAD R-HSA-5362768
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Switching of origins to a post-replicative state R-HSA-69052
Hedgehog ligand biogenesis R-HSA-5358346
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Disorders of transmembrane transporters R-HSA-5619115
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Nuclear events mediated by NFE2L2 R-HSA-9759194
DNA Replication R-HSA-69306
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PTEN Regulation R-HSA-6807070
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of RNA R-HSA-8953854
MAPK family signaling cascades R-HSA-5683057
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle R-HSA-1640170
Activation of NF-kappaB in B cells R-HSA-1169091
FCERI mediated NF-kB activation R-HSA-2871837
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by ROBO receptors R-HSA-376176
Hedgehog ligand biogenesis R-HSA-5358346
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cell Cycle, Mitotic R-HSA-69278
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by NOTCH R-HSA-157118
UCH proteinases R-HSA-5689603
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of polyamines R-HSA-351202
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RAF/MAP kinase cascade R-HSA-5673001
KEAP1-NFE2L2 pathway R-HSA-9755511
Transcriptional regulation by RUNX2 R-HSA-8878166
Stabilization of p53 R-HSA-69541
G2/M Checkpoints R-HSA-69481
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by WNT R-HSA-195721
Intracellular signaling by second messengers R-HSA-9006925
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Developmental Biology R-HSA-1266738
G2/M Transition R-HSA-69275
Interleukin-1 family signaling R-HSA-446652
TCR signaling R-HSA-202403
Programmed Cell Death R-HSA-5357801
Separation of Sister Chromatids R-HSA-2467813
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of RAS by GAPs R-HSA-5658442
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK6/MAPK4 signaling R-HSA-5687128
Hh mutants are degraded by ERAD R-HSA-5362768
Metabolism of amino acids and derivatives R-HSA-71291
Disease R-HSA-1643685
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of GLI2 by the proteasome R-HSA-5610783
Ub-specific processing proteases R-HSA-5689880
Regulation of RUNX3 expression and activity R-HSA-8941858
MAPK1/MAPK3 signaling R-HSA-5684996
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by Hedgehog R-HSA-5358351
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Beta-catenin independent WNT signaling R-HSA-3858494
Infectious disease R-HSA-5663205
Cell Cycle Checkpoints R-HSA-69620
ABC-family proteins mediated transport R-HSA-382556
Nervous system development R-HSA-9675108
Hedgehog 'off' state R-HSA-5610787
Signal Transduction R-HSA-162582
Degradation of AXIN R-HSA-4641257
Mitotic G1 phase and G1/S transition R-HSA-453279
Axon guidance R-HSA-422475
Metabolism R-HSA-1430728
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Immune System R-HSA-168256
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Adaptive Immune System R-HSA-1280218
Cellular responses to stress R-HSA-2262752
M Phase R-HSA-68886
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog 'on' state R-HSA-5632684
Cellular response to hypoxia R-HSA-1234174
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of DVL R-HSA-4641258
Negative regulation of NOTCH4 signaling R-HSA-9604323
Mitotic Anaphase R-HSA-68882
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Deubiquitination R-HSA-5688426
Cellular responses to stimuli R-HSA-8953897
p53-Independent DNA Damage Response R-HSA-69610
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic Metaphase and Anaphase R-HSA-2555396
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX1 R-HSA-8878171
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Generic Transcription Pathway R-HSA-212436
HIV Infection R-HSA-162906
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX3 R-HSA-8878159
Asymmetric localization of PCP proteins R-HSA-4608870
Apoptosis R-HSA-109581
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cellular response to chemical stress R-HSA-9711123
Metabolism of proteins R-HSA-392499
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
PCP/CE pathway R-HSA-4086400
Innate Immune System R-HSA-168249
Assembly of the pre-replicative complex R-HSA-68867
Neddylation R-HSA-8951664
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by NOTCH4 R-HSA-9013694
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Orc1 removal from chromatin R-HSA-68949
Interleukin-1 signaling R-HSA-9020702
Regulation of PTEN stability and activity R-HSA-8948751
DNA Replication Pre-Initiation R-HSA-69002
Antigen processing-Cross presentation R-HSA-1236975
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
ER-Phagosome pathway R-HSA-1236974
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by Interleukins R-HSA-449147
Class I MHC mediated antigen processing & presentation R-HSA-983169
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of RUNX2 expression and activity R-HSA-8939902
G1/S Transition R-HSA-69206
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
ABC transporter disorders R-HSA-5619084
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of Apoptosis R-HSA-169911
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Downstream TCR signaling R-HSA-202424
Transport of small molecules R-HSA-382551
Switching of origins to a post-replicative state R-HSA-69052
Mitotic G2-G2/M phases R-HSA-453274
C-type lectin receptors (CLRs) R-HSA-5621481
Synthesis of DNA R-HSA-69239
Regulation of mitotic cell cycle R-HSA-453276
Gene expression (Transcription) R-HSA-74160
Disorders of transmembrane transporters R-HSA-5619115
Vif-mediated degradation of APOBEC3G R-HSA-180585
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of GLI1 by the proteasome R-HSA-5610780
PIP3 activates AKT signaling R-HSA-1257604
Post-translational protein modification R-HSA-597592
S Phase R-HSA-69242
Host Interactions of HIV factors R-HSA-162909
Metabolism R-HSA-1430728
Axon guidance R-HSA-422475
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
HIV Infection R-HSA-162906
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of DVL R-HSA-4641258
Host Interactions of HIV factors R-HSA-162909
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Hedgehog R-HSA-5358351
Signaling by Interleukins R-HSA-449147
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
RAF/MAP kinase cascade R-HSA-5673001
Nuclear events mediated by NFE2L2 R-HSA-9759194
ABC-family proteins mediated transport R-HSA-382556
Innate Immune System R-HSA-168249
DNA Replication Pre-Initiation R-HSA-69002
Hedgehog 'off' state R-HSA-5610787
Stabilization of p53 R-HSA-69541
Regulation of RAS by GAPs R-HSA-5658442
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by ROBO receptors R-HSA-376176
Class I MHC mediated antigen processing & presentation R-HSA-983169
PCP/CE pathway R-HSA-4086400
p53-Dependent G1 DNA Damage Response R-HSA-69563
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of AXIN R-HSA-4641257
DNA Replication R-HSA-69306
Negative regulation of NOTCH4 signaling R-HSA-9604323
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic G2-G2/M phases R-HSA-453274
FCERI mediated NF-kB activation R-HSA-2871837
Synthesis of DNA R-HSA-69239
Signal Transduction R-HSA-162582
Infectious disease R-HSA-5663205
PIP3 activates AKT signaling R-HSA-1257604
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Disease R-HSA-1643685
Regulation of RUNX3 expression and activity R-HSA-8941858
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ub-specific processing proteases R-HSA-5689880
Programmed Cell Death R-HSA-5357801
Cellular responses to stimuli R-HSA-8953897
Degradation of beta-catenin by the destruction complex R-HSA-195253
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic Metaphase and Anaphase R-HSA-2555396
Transcriptional regulation by RUNX3 R-HSA-8878159
Deubiquitination R-HSA-5688426
Cyclin E associated events during G1/S transition R-HSA-69202
KEAP1-NFE2L2 pathway R-HSA-9755511
Interleukin-1 signaling R-HSA-9020702
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Nervous system development R-HSA-9675108
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle, Mitotic R-HSA-69278
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by NOTCH4 R-HSA-9013694
Hh mutants are degraded by ERAD R-HSA-5362768
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Separation of Sister Chromatids R-HSA-2467813
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
ABC transporter disorders R-HSA-5619084
Neddylation R-HSA-8951664
Asymmetric localization of PCP proteins R-HSA-4608870
Downstream TCR signaling R-HSA-202424
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog 'on' state R-HSA-5632684
Developmental Biology R-HSA-1266738
Disorders of transmembrane transporters R-HSA-5619115
Hh mutants abrogate ligand secretion R-HSA-5387390
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of mitotic cell cycle R-HSA-453276
Beta-catenin independent WNT signaling R-HSA-3858494
G1/S Transition R-HSA-69206
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of GLI1 by the proteasome R-HSA-5610780
Interleukin-1 family signaling R-HSA-446652
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
M Phase R-HSA-68886
Gene expression (Transcription) R-HSA-74160
Metabolism of RNA R-HSA-8953854
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by WNT R-HSA-195721
Generic Transcription Pathway R-HSA-212436
Metabolism of proteins R-HSA-392499
Cytokine Signaling in Immune system R-HSA-1280215
Vpu mediated degradation of CD4 R-HSA-180534
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Immune System R-HSA-168256
Mitotic G1 phase and G1/S transition R-HSA-453279
TCF dependent signaling in response to WNT R-HSA-201681
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G1/S DNA Damage Checkpoints R-HSA-69615
p53-Independent DNA Damage Response R-HSA-69610
Signaling by NOTCH R-HSA-157118
G2/M Transition R-HSA-69275
MAPK family signaling cascades R-HSA-5683057
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism of polyamines R-HSA-351202
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of PTEN stability and activity R-HSA-8948751
Switching of origins to a post-replicative state R-HSA-69052
Intracellular signaling by second messengers R-HSA-9006925
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RNA Polymerase II Transcription R-HSA-73857
Assembly of the pre-replicative complex R-HSA-68867
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stress R-HSA-2262752
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX1 R-HSA-8878171
PTEN Regulation R-HSA-6807070
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism of amino acids and derivatives R-HSA-71291
Orc1 removal from chromatin R-HSA-68949
Adaptive Immune System R-HSA-1280218
Transport of small molecules R-HSA-382551
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TCR signaling R-HSA-202403
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of Apoptosis R-HSA-169911
S Phase R-HSA-69242
G2/M Checkpoints R-HSA-69481
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular response to chemical stress R-HSA-9711123
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX2 R-HSA-8878166
UCH proteinases R-HSA-5689603
Post-translational protein modification R-HSA-597592
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular response to hypoxia R-HSA-1234174
ER-Phagosome pathway R-HSA-1236974
Mitotic Anaphase R-HSA-68882
Apoptosis R-HSA-109581
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog ligand biogenesis R-HSA-5358346
Cell Cycle Checkpoints R-HSA-69620

Expression Atlas ENSG00000013275
NCBI gene (formerly Entrezgene) 5704
GeneCards 9551
HGNC Symbol HGNC:9551
MIM gene 602707
UniProtKB Gene Name P43686
WikiGene 5704
Gene: PSMB2
Ensembl ID : ENSG00000126067
Description: proteasome 20S subunit beta 2
Gene Synonyms: HC7-I
6 APIs:
218 Possible Orthologues:

G1/S Transition R-HSA-69206
Signaling by NOTCH R-HSA-157118
PIP3 activates AKT signaling R-HSA-1257604
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hedgehog 'off' state R-HSA-5610787
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of PTEN stability and activity R-HSA-8948751
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PCP/CE pathway R-HSA-4086400
Neddylation R-HSA-8951664
Transport of small molecules R-HSA-382551
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle Checkpoints R-HSA-69620
HIV Infection R-HSA-162906
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of RNA R-HSA-8953854
MAPK1/MAPK3 signaling R-HSA-5684996
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signal Transduction R-HSA-162582
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by NOTCH R-HSA-157118
Degradation of GLI2 by the proteasome R-HSA-5610783
Separation of Sister Chromatids R-HSA-2467813
Cytokine Signaling in Immune system R-HSA-1280215
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Anaphase R-HSA-68882
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Apoptosis R-HSA-109581
Activation of NF-kappaB in B cells R-HSA-1169091
DNA Replication R-HSA-69306
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
Host Interactions of HIV factors R-HSA-162909
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ABC-family proteins mediated transport R-HSA-382556
Innate Immune System R-HSA-168249
Antigen processing-Cross presentation R-HSA-1236975
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of DVL R-HSA-4641258
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK6/MAPK4 signaling R-HSA-5687128
Metabolism of proteins R-HSA-392499
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional regulation by RUNX1 R-HSA-8878171
Transcriptional regulation by RUNX2 R-HSA-8878166
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Transition R-HSA-69275
Downstream TCR signaling R-HSA-202424
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RAF/MAP kinase cascade R-HSA-5673001
S Phase R-HSA-69242
TCF dependent signaling in response to WNT R-HSA-201681
Assembly of the pre-replicative complex R-HSA-68867
Signaling by Interleukins R-HSA-449147
Metabolism of polyamines R-HSA-351202
Metabolism R-HSA-1430728
KEAP1-NFE2L2 pathway R-HSA-9755511
MAPK family signaling cascades R-HSA-5683057
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by WNT R-HSA-195721
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
PTEN Regulation R-HSA-6807070
FCERI mediated NF-kB activation R-HSA-2871837
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
CLEC7A (Dectin-1) signaling R-HSA-5607764
UCH proteinases R-HSA-5689603
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of RAS by GAPs R-HSA-5658442
TCR signaling R-HSA-202403
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G2-G2/M phases R-HSA-453274
ABC transporter disorders R-HSA-5619084
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Orc1 removal from chromatin R-HSA-68949
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by ROBO receptors R-HSA-376176
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular response to chemical stress R-HSA-9711123
Hedgehog ligand biogenesis R-HSA-5358346
Defective CFTR causes cystic fibrosis R-HSA-5678895
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of RUNX2 expression and activity R-HSA-8939902
Immune System R-HSA-168256
M Phase R-HSA-68886
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
G2/M Checkpoints R-HSA-69481
Adaptive Immune System R-HSA-1280218
Gene expression (Transcription) R-HSA-74160
Disorders of transmembrane transporters R-HSA-5619115
Switching of origins to a post-replicative state R-HSA-69052
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cyclin E associated events during G1/S transition R-HSA-69202
Synthesis of DNA R-HSA-69239
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of AXIN R-HSA-4641257
Mitotic Metaphase and Anaphase R-HSA-2555396
Beta-catenin independent WNT signaling R-HSA-3858494
Disease R-HSA-1643685
Stabilization of p53 R-HSA-69541
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle, Mitotic R-HSA-69278
Mitotic G1 phase and G1/S transition R-HSA-453279
ER-Phagosome pathway R-HSA-1236974
Hedgehog 'on' state R-HSA-5632684
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of mitotic cell cycle R-HSA-453276
Signaling by Hedgehog R-HSA-5358351
Ub-specific processing proteases R-HSA-5689880
Interleukin-1 signaling R-HSA-9020702
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of beta-catenin by the destruction complex R-HSA-195253
Negative regulation of NOTCH4 signaling R-HSA-9604323
Interleukin-1 family signaling R-HSA-446652
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Deubiquitination R-HSA-5688426
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Independent DNA Damage Response R-HSA-69610
Post-translational protein modification R-HSA-597592
RNA Polymerase II Transcription R-HSA-73857
Infectious disease R-HSA-5663205
DNA Replication Pre-Initiation R-HSA-69002
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle R-HSA-1640170
G1/S DNA Damage Checkpoints R-HSA-69615
Programmed Cell Death R-HSA-5357801
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of Apoptosis R-HSA-169911
Developmental Biology R-HSA-1266738
C-type lectin receptors (CLRs) R-HSA-5621481
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
G1/S Transition R-HSA-69206
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Vpu mediated degradation of CD4 R-HSA-180534
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic Anaphase R-HSA-68882
Infectious disease R-HSA-5663205
Cell Cycle Checkpoints R-HSA-69620
Neddylation R-HSA-8951664
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Assembly of the pre-replicative complex R-HSA-68867
Interleukin-1 family signaling R-HSA-446652
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Metabolism of proteins R-HSA-392499
Apoptosis R-HSA-109581
Downstream TCR signaling R-HSA-202424
ABC transporter disorders R-HSA-5619084
Antigen processing-Cross presentation R-HSA-1236975
UCH proteinases R-HSA-5689603
RNA Polymerase II Transcription R-HSA-73857
Negative regulation of NOTCH4 signaling R-HSA-9604323
Disease R-HSA-1643685
p53-Independent DNA Damage Response R-HSA-69610
Regulation of expression of SLITs and ROBOs R-HSA-9010553
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RAS by GAPs R-HSA-5658442
Signaling by WNT R-HSA-195721
Hh mutants abrogate ligand secretion R-HSA-5387390
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cytokine Signaling in Immune system R-HSA-1280215
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Innate Immune System R-HSA-168249
Intracellular signaling by second messengers R-HSA-9006925
DNA Replication R-HSA-69306
Hedgehog ligand biogenesis R-HSA-5358346
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Mitotic G2-G2/M phases R-HSA-453274
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by NOTCH4 R-HSA-9013694
Regulation of mitotic cell cycle R-HSA-453276
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Deubiquitination R-HSA-5688426
MAPK6/MAPK4 signaling R-HSA-5687128
Cell Cycle, Mitotic R-HSA-69278
Separation of Sister Chromatids R-HSA-2467813
Disorders of transmembrane transporters R-HSA-5619115
Regulation of RUNX2 expression and activity R-HSA-8939902
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of GLI1 by the proteasome R-HSA-5610780
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX3 R-HSA-8878159
Metabolism of RNA R-HSA-8953854
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Beta-catenin independent WNT signaling R-HSA-3858494
Programmed Cell Death R-HSA-5357801
ABC-family proteins mediated transport R-HSA-382556
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Adaptive Immune System R-HSA-1280218
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Ub-specific processing proteases R-HSA-5689880
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCF dependent signaling in response to WNT R-HSA-201681
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Developmental Biology R-HSA-1266738
Metabolism of polyamines R-HSA-351202
ER-Phagosome pathway R-HSA-1236974
Cellular response to chemical stress R-HSA-9711123
Activation of NF-kappaB in B cells R-HSA-1169091
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G2/M Transition R-HSA-69275
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Interleukins R-HSA-449147
DNA Replication Pre-Initiation R-HSA-69002
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of PTEN stability and activity R-HSA-8948751
Cell Cycle R-HSA-1640170
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PCP/CE pathway R-HSA-4086400
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to hypoxia R-HSA-1234174
Stabilization of p53 R-HSA-69541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
M Phase R-HSA-68886
Asymmetric localization of PCP proteins R-HSA-4608870
Signal Transduction R-HSA-162582
Metabolism of amino acids and derivatives R-HSA-71291
Gene expression (Transcription) R-HSA-74160
Hedgehog 'on' state R-HSA-5632684
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH R-HSA-157118
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cellular responses to stimuli R-HSA-8953897
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transport of small molecules R-HSA-382551
TCR signaling R-HSA-202403
Signaling by Hedgehog R-HSA-5358351
Regulation of RUNX3 expression and activity R-HSA-8941858
RAF/MAP kinase cascade R-HSA-5673001
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism R-HSA-1430728
Host Interactions of HIV factors R-HSA-162909
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Immune System R-HSA-168256
Interleukin-1 signaling R-HSA-9020702
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Axon guidance R-HSA-422475
G1/S DNA Damage Checkpoints R-HSA-69615
Post-translational protein modification R-HSA-597592
HIV Infection R-HSA-162906
Cyclin E associated events during G1/S transition R-HSA-69202
S Phase R-HSA-69242
MAPK family signaling cascades R-HSA-5683057
MAPK1/MAPK3 signaling R-HSA-5684996
G2/M Checkpoints R-HSA-69481
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of Apoptosis R-HSA-169911
Cellular responses to stress R-HSA-2262752
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by ROBO receptors R-HSA-376176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
C-type lectin receptors (CLRs) R-HSA-5621481
PTEN Regulation R-HSA-6807070
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Orc1 removal from chromatin R-HSA-68949
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of AXIN R-HSA-4641257
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
CLEC7A (Dectin-1) signaling R-HSA-5607764
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Nervous system development R-HSA-9675108
G1/S Transition R-HSA-69206
Vif-mediated degradation of APOBEC3G R-HSA-180585
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Synthesis of DNA R-HSA-69239
Class I MHC mediated antigen processing & presentation R-HSA-983169
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Generic Transcription Pathway R-HSA-212436
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Degradation of DVL R-HSA-4641258
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional regulation by RUNX2 R-HSA-8878166
KEAP1-NFE2L2 pathway R-HSA-9755511
MAPK6/MAPK4 signaling R-HSA-5687128
Developmental Biology R-HSA-1266738
Activation of NF-kappaB in B cells R-HSA-1169091
Synthesis of DNA R-HSA-69239
Regulation of Apoptosis R-HSA-169911
Hedgehog 'off' state R-HSA-5610787
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX3 R-HSA-8878159
PTEN Regulation R-HSA-6807070
Stabilization of p53 R-HSA-69541
Regulation of RAS by GAPs R-HSA-5658442
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-1 family signaling R-HSA-446652
Orc1 removal from chromatin R-HSA-68949
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by Interleukins R-HSA-449147
Nuclear events mediated by NFE2L2 R-HSA-9759194
Intracellular signaling by second messengers R-HSA-9006925
Vpu mediated degradation of CD4 R-HSA-180534
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Apoptosis R-HSA-109581
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of beta-catenin by the destruction complex R-HSA-195253
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
ABC-family proteins mediated transport R-HSA-382556
G2/M Checkpoints R-HSA-69481
Transport of small molecules R-HSA-382551
Host Interactions of HIV factors R-HSA-162909
Cellular response to chemical stress R-HSA-9711123
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX2 R-HSA-8878166
Disorders of transmembrane transporters R-HSA-5619115
Deubiquitination R-HSA-5688426
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of DVL R-HSA-4641258
Immune System R-HSA-168256
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by NOTCH R-HSA-157118
TCR signaling R-HSA-202403
Neddylation R-HSA-8951664
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Programmed Cell Death R-HSA-5357801
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
Disease R-HSA-1643685
Beta-catenin independent WNT signaling R-HSA-3858494
Cell Cycle, Mitotic R-HSA-69278
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of proteins R-HSA-392499
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX1 R-HSA-8878171
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Asymmetric localization of PCP proteins R-HSA-4608870
HIV Infection R-HSA-162906
RAF/MAP kinase cascade R-HSA-5673001
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
DNA Replication R-HSA-69306
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Separation of Sister Chromatids R-HSA-2467813
DNA Replication Pre-Initiation R-HSA-69002
Antigen processing-Cross presentation R-HSA-1236975
MAPK family signaling cascades R-HSA-5683057
Metabolism of polyamines R-HSA-351202
Defective CFTR causes cystic fibrosis R-HSA-5678895
KEAP1-NFE2L2 pathway R-HSA-9755511
ER-Phagosome pathway R-HSA-1236974
RNA Polymerase II Transcription R-HSA-73857
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by WNT R-HSA-195721
Gene expression (Transcription) R-HSA-74160
Class I MHC mediated antigen processing & presentation R-HSA-983169
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PIP3 activates AKT signaling R-HSA-1257604
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular response to hypoxia R-HSA-1234174
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by Hedgehog R-HSA-5358351
Metabolism of RNA R-HSA-8953854
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of GLI2 by the proteasome R-HSA-5610783
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ub-specific processing proteases R-HSA-5689880
PCP/CE pathway R-HSA-4086400
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of amino acids and derivatives R-HSA-71291
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Switching of origins to a post-replicative state R-HSA-69052
UCH proteinases R-HSA-5689603
Post-translational protein modification R-HSA-597592
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by ROBO receptors R-HSA-376176
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of AXIN R-HSA-4641257
Innate Immune System R-HSA-168249
Downstream TCR signaling R-HSA-202424
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signal Transduction R-HSA-162582
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic Anaphase R-HSA-68882
TCF dependent signaling in response to WNT R-HSA-201681
M Phase R-HSA-68886
p53-Independent DNA Damage Response R-HSA-69610
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism R-HSA-1430728
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hedgehog 'on' state R-HSA-5632684
Axon guidance R-HSA-422475
Generic Transcription Pathway R-HSA-212436
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Transition R-HSA-69275
Cytokine Signaling in Immune system R-HSA-1280215
ABC transporter disorders R-HSA-5619084
Signaling by NOTCH4 R-HSA-9013694
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cell Cycle Checkpoints R-HSA-69620
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic Metaphase and Anaphase R-HSA-2555396
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
S Phase R-HSA-69242
Interleukin-1 signaling R-HSA-9020702
Regulation of RUNX2 expression and activity R-HSA-8939902
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular responses to stimuli R-HSA-8953897
Adaptive Immune System R-HSA-1280218
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of GLI1 by the proteasome R-HSA-5610780
C-type lectin receptors (CLRs) R-HSA-5621481
Synthesis of DNA R-HSA-69239
Cellular response to hypoxia R-HSA-1234174
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular responses to stress R-HSA-2262752
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK family signaling cascades R-HSA-5683057
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of GLI2 by the proteasome R-HSA-5610783
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
PCP/CE pathway R-HSA-4086400
Signaling by NOTCH4 R-HSA-9013694
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle Checkpoints R-HSA-69620
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism R-HSA-1430728
Deubiquitination R-HSA-5688426
Orc1 removal from chromatin R-HSA-68949
S Phase R-HSA-69242
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cyclin E associated events during G1/S transition R-HSA-69202
DNA Replication R-HSA-69306
Degradation of AXIN R-HSA-4641257
Signal Transduction R-HSA-162582
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Interleukin-1 family signaling R-HSA-446652
Degradation of GLI1 by the proteasome R-HSA-5610780
ABC-family proteins mediated transport R-HSA-382556
Cellular responses to stimuli R-HSA-8953897
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
KEAP1-NFE2L2 pathway R-HSA-9755511
Ub-specific processing proteases R-HSA-5689880
p53-Independent DNA Damage Response R-HSA-69610
Disease R-HSA-1643685
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Downstream TCR signaling R-HSA-202424
ER-Phagosome pathway R-HSA-1236974
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Assembly of the pre-replicative complex R-HSA-68867
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Infectious disease R-HSA-5663205
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by ROBO receptors R-HSA-376176
ABC transporter disorders R-HSA-5619084
Intracellular signaling by second messengers R-HSA-9006925
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Transcriptional regulation by RUNX3 R-HSA-8878159
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Axon guidance R-HSA-422475
Beta-catenin independent WNT signaling R-HSA-3858494
Hh mutants are degraded by ERAD R-HSA-5362768
PTEN Regulation R-HSA-6807070
Vpu mediated degradation of CD4 R-HSA-180534
Cell Cycle, Mitotic R-HSA-69278
FCERI mediated NF-kB activation R-HSA-2871837
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Stabilization of p53 R-HSA-69541
Programmed Cell Death R-HSA-5357801
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Antigen processing-Cross presentation R-HSA-1236975
C-type lectin receptors (CLRs) R-HSA-5621481
Negative regulation of NOTCH4 signaling R-HSA-9604323
Mitotic Metaphase and Anaphase R-HSA-2555396
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cytokine Signaling in Immune system R-HSA-1280215
Nervous system development R-HSA-9675108
Switching of origins to a post-replicative state R-HSA-69052
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Gene expression (Transcription) R-HSA-74160
Developmental Biology R-HSA-1266738
Regulation of RAS by GAPs R-HSA-5658442
G1/S Transition R-HSA-69206
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Interleukin-1 signaling R-HSA-9020702
Degradation of DVL R-HSA-4641258
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Metabolism of polyamines R-HSA-351202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Generic Transcription Pathway R-HSA-212436
Mitotic Anaphase R-HSA-68882
G2/M Transition R-HSA-69275
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cell Cycle R-HSA-1640170
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
UCH proteinases R-HSA-5689603
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Apoptosis R-HSA-109581
Regulation of mitotic cell cycle R-HSA-453276
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX1 R-HSA-8878171
HIV Infection R-HSA-162906
Mitotic G2-G2/M phases R-HSA-453274
Hh mutants abrogate ligand secretion R-HSA-5387390
TCF dependent signaling in response to WNT R-HSA-201681
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
G1/S DNA Damage Checkpoints R-HSA-69615
Disorders of transmembrane transporters R-HSA-5619115
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of PTEN stability and activity R-HSA-8948751
Cellular response to chemical stress R-HSA-9711123
TCR signaling R-HSA-202403
Signaling by Hedgehog R-HSA-5358351
Metabolism of proteins R-HSA-392499
Mitotic G1 phase and G1/S transition R-HSA-453279
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Neddylation R-HSA-8951664
RAF/MAP kinase cascade R-HSA-5673001
RNA Polymerase II Transcription R-HSA-73857
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK6/MAPK4 signaling R-HSA-5687128
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of amino acids and derivatives R-HSA-71291
DNA Replication Pre-Initiation R-HSA-69002
G2/M Checkpoints R-HSA-69481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK1/MAPK3 signaling R-HSA-5684996
Class I MHC mediated antigen processing & presentation R-HSA-983169
Post-translational protein modification R-HSA-597592
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of Apoptosis R-HSA-169911
M Phase R-HSA-68886
Signaling by WNT R-HSA-195721
Vif-mediated degradation of APOBEC3G R-HSA-180585
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by Interleukins R-HSA-449147
Hedgehog 'off' state R-HSA-5610787
Metabolism of RNA R-HSA-8953854
Immune System R-HSA-168256
p53-Dependent G1 DNA Damage Response R-HSA-69563
Transport of small molecules R-HSA-382551
Host Interactions of HIV factors R-HSA-162909
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of RAS by GAPs R-HSA-5658442
Adaptive Immune System R-HSA-1280218
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX1 R-HSA-8878171
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
M Phase R-HSA-68886
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Axon guidance R-HSA-422475
Degradation of GLI2 by the proteasome R-HSA-5610783
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Apoptosis R-HSA-109581
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
ABC-family proteins mediated transport R-HSA-382556
G1/S DNA Damage Checkpoints R-HSA-69615
MAPK1/MAPK3 signaling R-HSA-5684996
Innate Immune System R-HSA-168249
Transcriptional regulation by RUNX3 R-HSA-8878159
Immune System R-HSA-168256
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Separation of Sister Chromatids R-HSA-2467813
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism R-HSA-1430728
Stabilization of p53 R-HSA-69541
Deubiquitination R-HSA-5688426
Negative regulation of NOTCH4 signaling R-HSA-9604323
Nuclear events mediated by NFE2L2 R-HSA-9759194
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of Apoptosis R-HSA-169911
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic G1 phase and G1/S transition R-HSA-453279
CLEC7A (Dectin-1) signaling R-HSA-5607764
Ub-specific processing proteases R-HSA-5689880
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
ER-Phagosome pathway R-HSA-1236974
Synthesis of DNA R-HSA-69239
PCP/CE pathway R-HSA-4086400
Cell Cycle, Mitotic R-HSA-69278
Cellular response to hypoxia R-HSA-1234174
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
C-type lectin receptors (CLRs) R-HSA-5621481
Signal Transduction R-HSA-162582
HIV Infection R-HSA-162906
G2/M Checkpoints R-HSA-69481
Regulation of RUNX2 expression and activity R-HSA-8939902
Host Interactions of HIV factors R-HSA-162909
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Activation of NF-kappaB in B cells R-HSA-1169091
RNA Polymerase II Transcription R-HSA-73857
PTEN Regulation R-HSA-6807070
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Nervous system development R-HSA-9675108
Metabolism of polyamines R-HSA-351202
Disorders of transmembrane transporters R-HSA-5619115
Signaling by WNT R-HSA-195721
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Disease R-HSA-1643685
Degradation of beta-catenin by the destruction complex R-HSA-195253
Assembly of the pre-replicative complex R-HSA-68867
Cyclin E associated events during G1/S transition R-HSA-69202
Interleukin-1 signaling R-HSA-9020702
Downstream TCR signaling R-HSA-202424
Infectious disease R-HSA-5663205
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism of RNA R-HSA-8953854
Generic Transcription Pathway R-HSA-212436
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hedgehog 'on' state R-HSA-5632684
Programmed Cell Death R-HSA-5357801
Cellular responses to stress R-HSA-2262752
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cytokine Signaling in Immune system R-HSA-1280215
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Gene expression (Transcription) R-HSA-74160
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic Anaphase R-HSA-68882
TCR signaling R-HSA-202403
MAPK family signaling cascades R-HSA-5683057
KEAP1-NFE2L2 pathway R-HSA-9755511
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of amino acids and derivatives R-HSA-71291
MAPK6/MAPK4 signaling R-HSA-5687128
Transport of small molecules R-HSA-382551
Defective CFTR causes cystic fibrosis R-HSA-5678895
G1/S Transition R-HSA-69206
Hh mutants are degraded by ERAD R-HSA-5362768
Cell Cycle Checkpoints R-HSA-69620
Regulation of mitotic cell cycle R-HSA-453276
Degradation of AXIN R-HSA-4641257
DNA Replication R-HSA-69306
p53-Dependent G1 DNA Damage Response R-HSA-69563
Vpu mediated degradation of CD4 R-HSA-180534
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 family signaling R-HSA-446652
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Metaphase and Anaphase R-HSA-2555396
Switching of origins to a post-replicative state R-HSA-69052
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by Interleukins R-HSA-449147
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Post-translational protein modification R-HSA-597592
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Antigen processing-Cross presentation R-HSA-1236975
Developmental Biology R-HSA-1266738
Neddylation R-HSA-8951664
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic G2-G2/M phases R-HSA-453274
Signaling by NOTCH R-HSA-157118
DNA Replication Pre-Initiation R-HSA-69002
ABC transporter disorders R-HSA-5619084
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle R-HSA-1640170
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RUNX3 expression and activity R-HSA-8941858
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
p53-Independent DNA Damage Response R-HSA-69610
FCERI mediated NF-kB activation R-HSA-2871837
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Orc1 removal from chromatin R-HSA-68949
UCH proteinases R-HSA-5689603
Signaling by Hedgehog R-HSA-5358351
Degradation of GLI1 by the proteasome R-HSA-5610780
PIP3 activates AKT signaling R-HSA-1257604
Degradation of DVL R-HSA-4641258
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
S Phase R-HSA-69242
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G2/M Transition R-HSA-69275
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by ROBO receptors R-HSA-376176
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular responses to stimuli R-HSA-8953897
Metabolism of proteins R-HSA-392499
Cellular response to chemical stress R-HSA-9711123
MAPK1/MAPK3 signaling R-HSA-5684996
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle, Mitotic R-HSA-69278
Intracellular signaling by second messengers R-HSA-9006925
G1/S Transition R-HSA-69206
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
Cellular responses to stimuli R-HSA-8953897
Degradation of beta-catenin by the destruction complex R-HSA-195253
Nervous system development R-HSA-9675108
Infectious disease R-HSA-5663205
Cell Cycle R-HSA-1640170
PCP/CE pathway R-HSA-4086400
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of PTEN stability and activity R-HSA-8948751
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hedgehog ligand biogenesis R-HSA-5358346
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle Checkpoints R-HSA-69620
Signaling by Hedgehog R-HSA-5358351
Apoptosis R-HSA-109581
DNA Replication Pre-Initiation R-HSA-69002
Metabolism R-HSA-1430728
Disorders of transmembrane transporters R-HSA-5619115
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transport of small molecules R-HSA-382551
Downstream TCR signaling R-HSA-202424
Metabolism of polyamines R-HSA-351202
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular response to hypoxia R-HSA-1234174
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Independent DNA Damage Response R-HSA-69610
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic Anaphase R-HSA-68882
Activation of NF-kappaB in B cells R-HSA-1169091
Separation of Sister Chromatids R-HSA-2467813
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Orc1 removal from chromatin R-HSA-68949
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
FCERI mediated NF-kB activation R-HSA-2871837
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by WNT R-HSA-195721
Regulation of RUNX3 expression and activity R-HSA-8941858
Cytokine Signaling in Immune system R-HSA-1280215
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
UCH proteinases R-HSA-5689603
Synthesis of DNA R-HSA-69239
Deubiquitination R-HSA-5688426
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stress R-HSA-2262752
TCR signaling R-HSA-202403
HIV Infection R-HSA-162906
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
TCF dependent signaling in response to WNT R-HSA-201681
Neddylation R-HSA-8951664
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Vpu mediated degradation of CD4 R-HSA-180534
Disease R-HSA-1643685
Host Interactions of HIV factors R-HSA-162909
Interleukin-1 signaling R-HSA-9020702
Signaling by NOTCH4 R-HSA-9013694
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cyclin E associated events during G1/S transition R-HSA-69202
Defective CFTR causes cystic fibrosis R-HSA-5678895
M Phase R-HSA-68886
Metabolism of proteins R-HSA-392499
Negative regulation of NOTCH4 signaling R-HSA-9604323
Transcriptional regulation by RUNX2 R-HSA-8878166
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog 'on' state R-HSA-5632684
Gene expression (Transcription) R-HSA-74160
Degradation of DVL R-HSA-4641258
MAPK6/MAPK4 signaling R-HSA-5687128
Immune System R-HSA-168256
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Asymmetric localization of PCP proteins R-HSA-4608870
Stabilization of p53 R-HSA-69541
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of amino acids and derivatives R-HSA-71291
ABC transporter disorders R-HSA-5619084
ABC-family proteins mediated transport R-HSA-382556
Adaptive Immune System R-HSA-1280218
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of GLI2 by the proteasome R-HSA-5610783
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism of RNA R-HSA-8953854
Mitotic G2-G2/M phases R-HSA-453274
Signaling by ROBO receptors R-HSA-376176
Regulation of RAS by GAPs R-HSA-5658442
Antigen processing-Cross presentation R-HSA-1236975
RNA Polymerase II Transcription R-HSA-73857
PTEN Regulation R-HSA-6807070
Innate Immune System R-HSA-168249
Hedgehog 'off' state R-HSA-5610787
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
ER-Phagosome pathway R-HSA-1236974
Signaling by Interleukins R-HSA-449147
RAF/MAP kinase cascade R-HSA-5673001
Class I MHC mediated antigen processing & presentation R-HSA-983169
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX3 R-HSA-8878159
Nuclear events mediated by NFE2L2 R-HSA-9759194
G2/M Transition R-HSA-69275
DNA Replication R-HSA-69306
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1 DNA Damage Response R-HSA-69563
G2/M Checkpoints R-HSA-69481
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hh mutants are degraded by ERAD R-HSA-5362768
Ub-specific processing proteases R-HSA-5689880
Regulation of RUNX2 expression and activity R-HSA-8939902
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of Apoptosis R-HSA-169911
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
PIP3 activates AKT signaling R-HSA-1257604
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular response to chemical stress R-HSA-9711123
Post-translational protein modification R-HSA-597592
Signaling by NOTCH R-HSA-157118
Programmed Cell Death R-HSA-5357801
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Interleukin-1 family signaling R-HSA-446652
S Phase R-HSA-69242
Developmental Biology R-HSA-1266738
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Assembly of the pre-replicative complex R-HSA-68867
Beta-catenin independent WNT signaling R-HSA-3858494
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Switching of origins to a post-replicative state R-HSA-69052
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of mitotic cell cycle R-HSA-453276
Degradation of AXIN R-HSA-4641257
Transport of small molecules R-HSA-382551
Intracellular signaling by second messengers R-HSA-9006925
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G1/S DNA Damage Checkpoints R-HSA-69615
Infectious disease R-HSA-5663205
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Assembly of the pre-replicative complex R-HSA-68867
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
ABC-family proteins mediated transport R-HSA-382556
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC transporter disorders R-HSA-5619084
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by Interleukins R-HSA-449147
Signaling by WNT R-HSA-195721
Downstream TCR signaling R-HSA-202424
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Disease R-HSA-1643685
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Post-translational protein modification R-HSA-597592
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular responses to stimuli R-HSA-8953897
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
M Phase R-HSA-68886
Interleukin-1 signaling R-HSA-9020702
Regulation of PTEN stability and activity R-HSA-8948751
Stabilization of p53 R-HSA-69541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S Transition R-HSA-69206
CLEC7A (Dectin-1) signaling R-HSA-5607764
Host Interactions of HIV factors R-HSA-162909
S Phase R-HSA-69242
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RAS by GAPs R-HSA-5658442
Innate Immune System R-HSA-168249
PTEN Regulation R-HSA-6807070
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transcriptional regulation by RUNX2 R-HSA-8878166
Orc1 removal from chromatin R-HSA-68949
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by ROBO receptors R-HSA-376176
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Developmental Biology R-HSA-1266738
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX3 R-HSA-8878159
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Independent DNA Damage Response R-HSA-69610
Nervous system development R-HSA-9675108
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog 'off' state R-HSA-5610787
DNA Replication R-HSA-69306
UCH proteinases R-HSA-5689603
Separation of Sister Chromatids R-HSA-2467813
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic G2-G2/M phases R-HSA-453274
FCERI mediated NF-kB activation R-HSA-2871837
Cyclin E associated events during G1/S transition R-HSA-69202
Programmed Cell Death R-HSA-5357801
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Mitotic Anaphase R-HSA-68882
Hh mutants abrogate ligand secretion R-HSA-5387390
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of RNA R-HSA-8953854
Regulation of Apoptosis R-HSA-169911
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PIP3 activates AKT signaling R-HSA-1257604
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle R-HSA-1640170
Cellular response to hypoxia R-HSA-1234174
Regulation of RUNX3 expression and activity R-HSA-8941858
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of RUNX2 expression and activity R-HSA-8939902
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH R-HSA-157118
Regulation of mitotic cell cycle R-HSA-453276
Synthesis of DNA R-HSA-69239
Beta-catenin independent WNT signaling R-HSA-3858494
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of polyamines R-HSA-351202
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Deubiquitination R-HSA-5688426
ER-Phagosome pathway R-HSA-1236974
Immune System R-HSA-168256
Axon guidance R-HSA-422475
Hedgehog 'on' state R-HSA-5632684
Ub-specific processing proteases R-HSA-5689880
Cellular responses to stress R-HSA-2262752
Disorders of transmembrane transporters R-HSA-5619115
Cell Cycle Checkpoints R-HSA-69620
G2/M Checkpoints R-HSA-69481
DNA Replication Pre-Initiation R-HSA-69002
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Metabolism of proteins R-HSA-392499
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of AXIN R-HSA-4641257
Mitotic Metaphase and Anaphase R-HSA-2555396
Activation of NF-kappaB in B cells R-HSA-1169091
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of DVL R-HSA-4641258
PCP/CE pathway R-HSA-4086400
RNA Polymerase II Transcription R-HSA-73857
Degradation of GLI2 by the proteasome R-HSA-5610783
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of amino acids and derivatives R-HSA-71291
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Vpu mediated degradation of CD4 R-HSA-180534
G2/M Transition R-HSA-69275
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Metabolism R-HSA-1430728
KEAP1-NFE2L2 pathway R-HSA-9755511
Interleukin-1 family signaling R-HSA-446652
Regulation of expression of SLITs and ROBOs R-HSA-9010553
HIV Infection R-HSA-162906
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cell Cycle, Mitotic R-HSA-69278
Neddylation R-HSA-8951664
Generic Transcription Pathway R-HSA-212436
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional regulation by RUNX1 R-HSA-8878171
Apoptosis R-HSA-109581
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Hedgehog R-HSA-5358351
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Defective CFTR causes cystic fibrosis R-HSA-5678895
TCR signaling R-HSA-202403
Antigen processing-Cross presentation R-HSA-1236975
Adaptive Immune System R-HSA-1280218
Mitotic G1 phase and G1/S transition R-HSA-453279
Switching of origins to a post-replicative state R-HSA-69052
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stimuli R-HSA-8953897
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
HIV Infection R-HSA-162906
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stress R-HSA-2262752
Separation of Sister Chromatids R-HSA-2467813
Metabolism of RNA R-HSA-8953854
PIP3 activates AKT signaling R-HSA-1257604
Generic Transcription Pathway R-HSA-212436
MAPK1/MAPK3 signaling R-HSA-5684996
FCERI mediated NF-kB activation R-HSA-2871837
Innate Immune System R-HSA-168249
Hedgehog 'on' state R-HSA-5632684
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cytokine Signaling in Immune system R-HSA-1280215
Axon guidance R-HSA-422475
DNA Replication R-HSA-69306
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by ROBO receptors R-HSA-376176
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Host Interactions of HIV factors R-HSA-162909
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Vpu mediated degradation of CD4 R-HSA-180534
Infectious disease R-HSA-5663205
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by WNT R-HSA-195721
Transport of small molecules R-HSA-382551
Signaling by Interleukins R-HSA-449147
Hh mutants abrogate ligand secretion R-HSA-5387390
Signal Transduction R-HSA-162582
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Dependent G1 DNA Damage Response R-HSA-69563
KEAP1-NFE2L2 pathway R-HSA-9755511
Synthesis of DNA R-HSA-69239
Regulation of mitotic cell cycle R-HSA-453276
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cyclin E associated events during G1/S transition R-HSA-69202
ABC-family proteins mediated transport R-HSA-382556
Disease R-HSA-1643685
Apoptosis R-HSA-109581
Metabolism of polyamines R-HSA-351202
Asymmetric localization of PCP proteins R-HSA-4608870
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of DVL R-HSA-4641258
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle Checkpoints R-HSA-69620
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Programmed Cell Death R-HSA-5357801
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by NOTCH4 R-HSA-9013694
Interleukin-1 family signaling R-HSA-446652
Deubiquitination R-HSA-5688426
UCH proteinases R-HSA-5689603
Metabolism R-HSA-1430728
M Phase R-HSA-68886
S Phase R-HSA-69242
Beta-catenin independent WNT signaling R-HSA-3858494
Antigen processing-Cross presentation R-HSA-1236975
Cellular response to chemical stress R-HSA-9711123
Downstream TCR signaling R-HSA-202424
Regulation of RUNX2 expression and activity R-HSA-8939902
Neddylation R-HSA-8951664
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Orc1 removal from chromatin R-HSA-68949
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog ligand biogenesis R-HSA-5358346
Cell Cycle R-HSA-1640170
Regulation of PTEN stability and activity R-HSA-8948751
Nervous system development R-HSA-9675108
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transcriptional regulation by RUNX2 R-HSA-8878166
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
C-type lectin receptors (CLRs) R-HSA-5621481
Immune System R-HSA-168256
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Mitotic G2-G2/M phases R-HSA-453274
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of AXIN R-HSA-4641257
Signaling by Hedgehog R-HSA-5358351
Mitotic Anaphase R-HSA-68882
Signaling by NOTCH R-HSA-157118
Degradation of beta-catenin by the destruction complex R-HSA-195253
Adaptive Immune System R-HSA-1280218
G2/M Transition R-HSA-69275
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vif-mediated degradation of APOBEC3G R-HSA-180585
Metabolism of amino acids and derivatives R-HSA-71291
TCR signaling R-HSA-202403
G1/S Transition R-HSA-69206
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Independent DNA Damage Response R-HSA-69610
DNA Replication Pre-Initiation R-HSA-69002
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Negative regulation of NOTCH4 signaling R-HSA-9604323
ER-Phagosome pathway R-HSA-1236974
ABC transporter disorders R-HSA-5619084
Hedgehog 'off' state R-HSA-5610787
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
PCP/CE pathway R-HSA-4086400
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX1 R-HSA-8878171
TCF dependent signaling in response to WNT R-HSA-201681
PTEN Regulation R-HSA-6807070
G2/M Checkpoints R-HSA-69481
Activation of NF-kappaB in B cells R-HSA-1169091
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of Apoptosis R-HSA-169911
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of GLI1 by the proteasome R-HSA-5610780
CLEC7A (Dectin-1) signaling R-HSA-5607764
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic G1 phase and G1/S transition R-HSA-453279
Assembly of the pre-replicative complex R-HSA-68867
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RAS by GAPs R-HSA-5658442
Hh mutants are degraded by ERAD R-HSA-5362768
Disorders of transmembrane transporters R-HSA-5619115
Developmental Biology R-HSA-1266738
Stabilization of p53 R-HSA-69541
Switching of origins to a post-replicative state R-HSA-69052
Ub-specific processing proteases R-HSA-5689880
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 signaling R-HSA-9020702
RAF/MAP kinase cascade R-HSA-5673001
Intracellular signaling by second messengers R-HSA-9006925
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Disorders of transmembrane transporters R-HSA-5619115
Immune System R-HSA-168256
Cellular responses to stress R-HSA-2262752
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by ROBO receptors R-HSA-376176
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Nuclear events mediated by NFE2L2 R-HSA-9759194
Infectious disease R-HSA-5663205
PCP/CE pathway R-HSA-4086400
FCERI mediated NF-kB activation R-HSA-2871837
MAPK1/MAPK3 signaling R-HSA-5684996
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular responses to stimuli R-HSA-8953897
Apoptosis R-HSA-109581
Cellular response to hypoxia R-HSA-1234174
Regulation of RUNX3 expression and activity R-HSA-8941858
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCR signaling R-HSA-202403
Regulation of Apoptosis R-HSA-169911
Regulation of expression of SLITs and ROBOs R-HSA-9010553
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular response to chemical stress R-HSA-9711123
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
ABC transporter disorders R-HSA-5619084
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of RNA R-HSA-8953854
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RUNX2 expression and activity R-HSA-8939902
Asymmetric localization of PCP proteins R-HSA-4608870
Nervous system development R-HSA-9675108
Disease R-HSA-1643685
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
p53-Dependent G1 DNA Damage Response R-HSA-69563
C-type lectin receptors (CLRs) R-HSA-5621481
Cell Cycle R-HSA-1640170
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic G2-G2/M phases R-HSA-453274
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of GLI2 by the proteasome R-HSA-5610783
Mitotic Anaphase R-HSA-68882
Switching of origins to a post-replicative state R-HSA-69052
HIV Infection R-HSA-162906
RNA Polymerase II Transcription R-HSA-73857
DNA Replication Pre-Initiation R-HSA-69002
Signaling by Interleukins R-HSA-449147
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog 'on' state R-HSA-5632684
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 signaling R-HSA-9020702
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants are degraded by ERAD R-HSA-5362768
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Programmed Cell Death R-HSA-5357801
Post-translational protein modification R-HSA-597592
Host Interactions of HIV factors R-HSA-162909
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
PIP3 activates AKT signaling R-HSA-1257604
Mitotic G1 phase and G1/S transition R-HSA-453279
Synthesis of DNA R-HSA-69239
MAPK6/MAPK4 signaling R-HSA-5687128
Neddylation R-HSA-8951664
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TCF dependent signaling in response to WNT R-HSA-201681
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transcriptional regulation by RUNX2 R-HSA-8878166
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX3 R-HSA-8878159
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Generic Transcription Pathway R-HSA-212436
Signaling by WNT R-HSA-195721
Antigen processing-Cross presentation R-HSA-1236975
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of GLI1 by the proteasome R-HSA-5610780
Ub-specific processing proteases R-HSA-5689880
PTEN Regulation R-HSA-6807070
G2/M Transition R-HSA-69275
S Phase R-HSA-69242
RAF/MAP kinase cascade R-HSA-5673001
Deubiquitination R-HSA-5688426
Degradation of DVL R-HSA-4641258
Axon guidance R-HSA-422475
UCH proteinases R-HSA-5689603
Orc1 removal from chromatin R-HSA-68949
Hedgehog 'off' state R-HSA-5610787
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle Checkpoints R-HSA-69620
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G1/S Transition R-HSA-69206
Mitotic Metaphase and Anaphase R-HSA-2555396
Adaptive Immune System R-HSA-1280218
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Developmental Biology R-HSA-1266738
Metabolism of proteins R-HSA-392499
p53-Independent DNA Damage Response R-HSA-69610
M Phase R-HSA-68886
Metabolism of polyamines R-HSA-351202
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by NOTCH R-HSA-157118
Separation of Sister Chromatids R-HSA-2467813
Cell Cycle, Mitotic R-HSA-69278
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Vif-mediated degradation of APOBEC3G R-HSA-180585
Interleukin-1 family signaling R-HSA-446652
ER-Phagosome pathway R-HSA-1236974
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of mitotic cell cycle R-HSA-453276
Degradation of AXIN R-HSA-4641257
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Innate Immune System R-HSA-168249
Vpu mediated degradation of CD4 R-HSA-180534
Assembly of the pre-replicative complex R-HSA-68867
G2/M Checkpoints R-HSA-69481
Intracellular signaling by second messengers R-HSA-9006925
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Stabilization of p53 R-HSA-69541
Signaling by NOTCH4 R-HSA-9013694
Cyclin E associated events during G1/S transition R-HSA-69202
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of RAS by GAPs R-HSA-5658442
ABC-family proteins mediated transport R-HSA-382556
Transport of small molecules R-HSA-382551
DNA Replication R-HSA-69306
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by Hedgehog R-HSA-5358351
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream TCR signaling R-HSA-202424
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Activation of NF-kappaB in B cells R-HSA-1169091
Gene expression (Transcription) R-HSA-74160
Metabolism R-HSA-1430728
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cell Cycle Checkpoints R-HSA-69620
Disease R-HSA-1643685
Transport of small molecules R-HSA-382551
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G2/M Checkpoints R-HSA-69481
Degradation of beta-catenin by the destruction complex R-HSA-195253
Neddylation R-HSA-8951664
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Interleukin-1 signaling R-HSA-9020702
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Antigen processing-Cross presentation R-HSA-1236975
S Phase R-HSA-69242
Host Interactions of HIV factors R-HSA-162909
DNA Replication Pre-Initiation R-HSA-69002
Metabolism of polyamines R-HSA-351202
Signaling by NOTCH R-HSA-157118
Programmed Cell Death R-HSA-5357801
Apoptosis R-HSA-109581
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 family signaling R-HSA-446652
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Stabilization of p53 R-HSA-69541
Degradation of GLI1 by the proteasome R-HSA-5610780
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Mitotic Metaphase and Anaphase R-HSA-2555396
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog 'on' state R-HSA-5632684
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
UCH proteinases R-HSA-5689603
Developmental Biology R-HSA-1266738
Regulation of mitotic cell cycle R-HSA-453276
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
M Phase R-HSA-68886
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transcriptional regulation by RUNX2 R-HSA-8878166
PCP/CE pathway R-HSA-4086400
Innate Immune System R-HSA-168249
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of Apoptosis R-HSA-169911
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
Degradation of DVL R-HSA-4641258
G2/M Transition R-HSA-69275
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Independent DNA Damage Response R-HSA-69610
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication R-HSA-69306
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic G2-G2/M phases R-HSA-453274
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic Anaphase R-HSA-68882
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Nuclear events mediated by NFE2L2 R-HSA-9759194
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Intracellular signaling by second messengers R-HSA-9006925
TCR signaling R-HSA-202403
PTEN Regulation R-HSA-6807070
PIP3 activates AKT signaling R-HSA-1257604
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism of proteins R-HSA-392499
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism R-HSA-1430728
Signaling by ROBO receptors R-HSA-376176
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic G1 phase and G1/S transition R-HSA-453279
Cytokine Signaling in Immune system R-HSA-1280215
RNA Polymerase II Transcription R-HSA-73857
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stress R-HSA-2262752
Regulation of RAS by GAPs R-HSA-5658442
Generic Transcription Pathway R-HSA-212436
Vif-mediated degradation of APOBEC3G R-HSA-180585
G1/S DNA Damage Checkpoints R-HSA-69615
Deubiquitination R-HSA-5688426
CLEC7A (Dectin-1) signaling R-HSA-5607764
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Negative regulation of NOTCH4 signaling R-HSA-9604323
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX3 R-HSA-8878159
Cellular response to hypoxia R-HSA-1234174
MAPK6/MAPK4 signaling R-HSA-5687128
Switching of origins to a post-replicative state R-HSA-69052
Signaling by WNT R-HSA-195721
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G1/S Transition R-HSA-69206
Activation of NF-kappaB in B cells R-HSA-1169091
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stimuli R-HSA-8953897
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by Interleukins R-HSA-449147
Ub-specific processing proteases R-HSA-5689880
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
Hedgehog 'off' state R-HSA-5610787
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Orc1 removal from chromatin R-HSA-68949
KEAP1-NFE2L2 pathway R-HSA-9755511
Assembly of the pre-replicative complex R-HSA-68867
Axon guidance R-HSA-422475
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Immune System R-HSA-168256
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by NOTCH4 R-HSA-9013694
Degradation of GLI2 by the proteasome R-HSA-5610783
Hedgehog ligand biogenesis R-HSA-5358346
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cell Cycle R-HSA-1640170
Metabolism of RNA R-HSA-8953854
ER-Phagosome pathway R-HSA-1236974
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
HIV Infection R-HSA-162906
Signaling by Hedgehog R-HSA-5358351
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC transporter disorders R-HSA-5619084
Hh mutants abrogate ligand secretion R-HSA-5387390
Signal Transduction R-HSA-162582
Cellular response to chemical stress R-HSA-9711123
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of RUNX2 expression and activity R-HSA-8939902
Downstream TCR signaling R-HSA-202424
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of AXIN R-HSA-4641257
Separation of Sister Chromatids R-HSA-2467813
Disorders of transmembrane transporters R-HSA-5619115
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of RUNX3 expression and activity R-HSA-8941858
Hh mutants are degraded by ERAD R-HSA-5362768
Transcriptional regulation by RUNX1 R-HSA-8878171
Metabolism of RNA R-HSA-8953854
Mitotic G2-G2/M phases R-HSA-453274
G1/S DNA Damage Checkpoints R-HSA-69615
Cell Cycle R-HSA-1640170
DNA Replication R-HSA-69306
Transport of small molecules R-HSA-382551
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of polyamines R-HSA-351202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by WNT R-HSA-195721
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle, Mitotic R-HSA-69278
Disease R-HSA-1643685
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Checkpoints R-HSA-69481
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Separation of Sister Chromatids R-HSA-2467813
Regulation of mitotic cell cycle R-HSA-453276
Apoptosis R-HSA-109581
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cytokine Signaling in Immune system R-HSA-1280215
Adaptive Immune System R-HSA-1280218
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle Checkpoints R-HSA-69620
Innate Immune System R-HSA-168249
G1/S Transition R-HSA-69206
Metabolism of proteins R-HSA-392499
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transcriptional regulation by RUNX3 R-HSA-8878159
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RNA Polymerase II Transcription R-HSA-73857
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Hh mutants are degraded by ERAD R-HSA-5362768
Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing-Cross presentation R-HSA-1236975
Signaling by the B Cell Receptor (BCR) R-HSA-983705
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK family signaling cascades R-HSA-5683057
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
ER-Phagosome pathway R-HSA-1236974
Infectious disease R-HSA-5663205
PTEN Regulation R-HSA-6807070
ABC transporter disorders R-HSA-5619084
HIV Infection R-HSA-162906
PCP/CE pathway R-HSA-4086400
Orc1 removal from chromatin R-HSA-68949
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
M Phase R-HSA-68886
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism R-HSA-1430728
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transcriptional regulation by RUNX1 R-HSA-8878171
KEAP1-NFE2L2 pathway R-HSA-9755511
Switching of origins to a post-replicative state R-HSA-69052
Degradation of GLI1 by the proteasome R-HSA-5610780
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
TCR signaling R-HSA-202403
Regulation of PTEN stability and activity R-HSA-8948751
Cellular responses to stress R-HSA-2262752
G2/M Transition R-HSA-69275
Signal Transduction R-HSA-162582
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hedgehog 'on' state R-HSA-5632684
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular response to chemical stress R-HSA-9711123
Host Interactions of HIV factors R-HSA-162909
Nervous system development R-HSA-9675108
Immune System R-HSA-168256
Assembly of the pre-replicative complex R-HSA-68867
RAF/MAP kinase cascade R-HSA-5673001
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of Apoptosis R-HSA-169911
Disorders of transmembrane transporters R-HSA-5619115
Stabilization of p53 R-HSA-69541
Hedgehog ligand biogenesis R-HSA-5358346
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by NOTCH R-HSA-157118
Intracellular signaling by second messengers R-HSA-9006925
Programmed Cell Death R-HSA-5357801
Activation of NF-kappaB in B cells R-HSA-1169091
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
UCH proteinases R-HSA-5689603
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ABC-family proteins mediated transport R-HSA-382556
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 signaling R-HSA-9020702
Signaling by Hedgehog R-HSA-5358351
Signaling by NOTCH4 R-HSA-9013694
Regulation of RAS by GAPs R-HSA-5658442
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of beta-catenin by the destruction complex R-HSA-195253
Vpu mediated degradation of CD4 R-HSA-180534
Gene expression (Transcription) R-HSA-74160
Ub-specific processing proteases R-HSA-5689880
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic Anaphase R-HSA-68882
Degradation of AXIN R-HSA-4641257
Signaling by Interleukins R-HSA-449147
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of RUNX3 expression and activity R-HSA-8941858
Developmental Biology R-HSA-1266738
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
MAPK1/MAPK3 signaling R-HSA-5684996
FCERI mediated NF-kB activation R-HSA-2871837
S Phase R-HSA-69242
PIP3 activates AKT signaling R-HSA-1257604
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by ROBO receptors R-HSA-376176
Degradation of DVL R-HSA-4641258
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular response to hypoxia R-HSA-1234174
p53-Independent DNA Damage Response R-HSA-69610
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK6/MAPK4 signaling R-HSA-5687128
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Generic Transcription Pathway R-HSA-212436
Synthesis of DNA R-HSA-69239
Deubiquitination R-HSA-5688426
Cellular responses to stimuli R-HSA-8953897
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Metaphase and Anaphase R-HSA-2555396
Post-translational protein modification R-HSA-597592
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX2 expression and activity R-HSA-8939902
Neddylation R-HSA-8951664
DNA Replication Pre-Initiation R-HSA-69002
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cyclin E associated events during G1/S transition R-HSA-69202
Axon guidance R-HSA-422475
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Downstream TCR signaling R-HSA-202424
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Negative regulation of NOTCH4 signaling R-HSA-9604323

Expression Atlas ENSG00000126067
NCBI gene (formerly Entrezgene) 5690
GeneCards 9539
HGNC Symbol HGNC:9539
MIM gene 602175
UniProtKB Gene Name P49721
WikiGene 5690
Gene: PSMB4
Ensembl ID : ENSG00000159377
Description: proteasome 20S subunit beta 4
Gene Synonyms: HN3,PROS26
6 APIs:
214 Possible Orthologues:

UCH proteinases R-HSA-5689603
Assembly of the pre-replicative complex R-HSA-68867
S Phase R-HSA-69242
Interleukin-1 signaling R-HSA-9020702
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S Transition R-HSA-69206
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by WNT R-HSA-195721
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Innate Immune System R-HSA-168249
Activation of NF-kappaB in B cells R-HSA-1169091
DNA Replication Pre-Initiation R-HSA-69002
Cellular response to chemical stress R-HSA-9711123
Negative regulation of NOTCH4 signaling R-HSA-9604323
TCR signaling R-HSA-202403
Separation of Sister Chromatids R-HSA-2467813
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of RNA R-HSA-8953854
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of AXIN R-HSA-4641257
Degradation of beta-catenin by the destruction complex R-HSA-195253
Class I MHC mediated antigen processing & presentation R-HSA-983169
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ER-Phagosome pathway R-HSA-1236974
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of polyamines R-HSA-351202
Hedgehog ligand biogenesis R-HSA-5358346
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
Immune System R-HSA-168256
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Nervous system development R-HSA-9675108
Generic Transcription Pathway R-HSA-212436
M Phase R-HSA-68886
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle Checkpoints R-HSA-69620
Cell Cycle R-HSA-1640170
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog 'on' state R-HSA-5632684
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transcriptional regulation by RUNX2 R-HSA-8878166
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular response to hypoxia R-HSA-1234174
Disease R-HSA-1643685
Mitotic G1 phase and G1/S transition R-HSA-453279
Intracellular signaling by second messengers R-HSA-9006925
Interleukin-1 family signaling R-HSA-446652
Cellular responses to stimuli R-HSA-8953897
PIP3 activates AKT signaling R-HSA-1257604
Cytokine Signaling in Immune system R-HSA-1280215
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hedgehog 'off' state R-HSA-5610787
Cell Cycle, Mitotic R-HSA-69278
Synthesis of DNA R-HSA-69239
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Switching of origins to a post-replicative state R-HSA-69052
ABC transporter disorders R-HSA-5619084
G2/M Transition R-HSA-69275
Vif-mediated degradation of APOBEC3G R-HSA-180585
Vpu mediated degradation of CD4 R-HSA-180534
Interleukin-1 signaling R-HSA-9020702
Transcriptional regulation by RUNX1 R-HSA-8878171
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of RAS by GAPs R-HSA-5658442
Developmental Biology R-HSA-1266738
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Antigen processing-Cross presentation R-HSA-1236975
Mitotic G2-G2/M phases R-HSA-453274
S Phase R-HSA-69242
Transport of small molecules R-HSA-382551
ABC-family proteins mediated transport R-HSA-382556
Infectious disease R-HSA-5663205
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by NOTCH4 R-HSA-9013694
Mitotic Anaphase R-HSA-68882
Disorders of transmembrane transporters R-HSA-5619115
G2/M Checkpoints R-HSA-69481
Adaptive Immune System R-HSA-1280218
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of Apoptosis R-HSA-169911
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
KEAP1-NFE2L2 pathway R-HSA-9755511
Hh mutants are degraded by ERAD R-HSA-5362768
Beta-catenin independent WNT signaling R-HSA-3858494
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Asymmetric localization of PCP proteins R-HSA-4608870
Gene expression (Transcription) R-HSA-74160
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Stabilization of p53 R-HSA-69541
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI2 by the proteasome R-HSA-5610783
p53-Independent DNA Damage Response R-HSA-69610
Orc1 removal from chromatin R-HSA-68949
RAF/MAP kinase cascade R-HSA-5673001
PTEN Regulation R-HSA-6807070
Regulation of mitotic cell cycle R-HSA-453276
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism of proteins R-HSA-392499
Cellular responses to stress R-HSA-2262752
Downstream TCR signaling R-HSA-202424
FCERI mediated NF-kB activation R-HSA-2871837
Ub-specific processing proteases R-HSA-5689880
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Post-translational protein modification R-HSA-597592
Signal Transduction R-HSA-162582
DNA Replication R-HSA-69306
PCP/CE pathway R-HSA-4086400
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Apoptosis R-HSA-109581
Axon guidance R-HSA-422475
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of DVL R-HSA-4641258
Transcriptional regulation by RUNX3 R-HSA-8878159
Metabolism R-HSA-1430728
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by NOTCH R-HSA-157118
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by ROBO receptors R-HSA-376176
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
HIV Infection R-HSA-162906
Neddylation R-HSA-8951664
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Deubiquitination R-HSA-5688426
Mitotic Metaphase and Anaphase R-HSA-2555396
CLEC7A (Dectin-1) signaling R-HSA-5607764
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by Interleukins R-HSA-449147
Signaling by Hedgehog R-HSA-5358351
Cytokine Signaling in Immune system R-HSA-1280215
Negative regulation of NOTCH4 signaling R-HSA-9604323
DNA Replication Pre-Initiation R-HSA-69002
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog 'off' state R-HSA-5610787
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog ligand biogenesis R-HSA-5358346
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Generic Transcription Pathway R-HSA-212436
G2/M Transition R-HSA-69275
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
PCP/CE pathway R-HSA-4086400
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of GLI1 by the proteasome R-HSA-5610780
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of PTEN stability and activity R-HSA-8948751
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Adaptive Immune System R-HSA-1280218
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism R-HSA-1430728
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RNA Polymerase II Transcription R-HSA-73857
Regulation of RUNX3 expression and activity R-HSA-8941858
Transcriptional regulation by RUNX2 R-HSA-8878166
Cell Cycle, Mitotic R-HSA-69278
Degradation of AXIN R-HSA-4641257
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stimuli R-HSA-8953897
Signaling by ROBO receptors R-HSA-376176
Hh mutants abrogate ligand secretion R-HSA-5387390
Orc1 removal from chromatin R-HSA-68949
Nervous system development R-HSA-9675108
Apoptosis R-HSA-109581
Defective CFTR causes cystic fibrosis R-HSA-5678895
ABC transporter disorders R-HSA-5619084
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
M Phase R-HSA-68886
S Phase R-HSA-69242
Synthesis of DNA R-HSA-69239
RAF/MAP kinase cascade R-HSA-5673001
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX1 R-HSA-8878171
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog 'on' state R-HSA-5632684
Cyclin E associated events during G1/S transition R-HSA-69202
Downstream TCR signaling R-HSA-202424
G2/M Checkpoints R-HSA-69481
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Assembly of the pre-replicative complex R-HSA-68867
Host Interactions of HIV factors R-HSA-162909
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
HIV Infection R-HSA-162906
FCERI mediated NF-kB activation R-HSA-2871837
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular response to hypoxia R-HSA-1234174
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
Neddylation R-HSA-8951664
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Anaphase R-HSA-68882
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of RNA R-HSA-8953854
Disorders of transmembrane transporters R-HSA-5619115
Signaling by Hedgehog R-HSA-5358351
TCR signaling R-HSA-202403
Regulation of RAS by GAPs R-HSA-5658442
Infectious disease R-HSA-5663205
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
C-type lectin receptors (CLRs) R-HSA-5621481
PIP3 activates AKT signaling R-HSA-1257604
Mitotic G2-G2/M phases R-HSA-453274
Signaling by NOTCH R-HSA-157118
Axon guidance R-HSA-422475
Immune System R-HSA-168256
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCF dependent signaling in response to WNT R-HSA-201681
MAPK family signaling cascades R-HSA-5683057
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of proteins R-HSA-392499
DNA Replication R-HSA-69306
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transport of small molecules R-HSA-382551
Metabolism of polyamines R-HSA-351202
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Switching of origins to a post-replicative state R-HSA-69052
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by WNT R-HSA-195721
Metabolism of amino acids and derivatives R-HSA-71291
Antigen processing-Cross presentation R-HSA-1236975
Deubiquitination R-HSA-5688426
Regulation of RUNX2 expression and activity R-HSA-8939902
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disease R-HSA-1643685
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by NOTCH4 R-HSA-9013694
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle R-HSA-1640170
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S Transition R-HSA-69206
Separation of Sister Chromatids R-HSA-2467813
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of Apoptosis R-HSA-169911
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cellular responses to stress R-HSA-2262752
Stabilization of p53 R-HSA-69541
Degradation of DVL R-HSA-4641258
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle Checkpoints R-HSA-69620
Transcriptional regulation by RUNX3 R-HSA-8878159
ABC-family proteins mediated transport R-HSA-382556
Interleukin-1 signaling R-HSA-9020702
ER-Phagosome pathway R-HSA-1236974
PTEN Regulation R-HSA-6807070
Innate Immune System R-HSA-168249
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK1/MAPK3 signaling R-HSA-5684996
Ub-specific processing proteases R-HSA-5689880
Programmed Cell Death R-HSA-5357801
Vif-mediated degradation of APOBEC3G R-HSA-180585
Interleukin-1 family signaling R-HSA-446652
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cyclin E associated events during G1/S transition R-HSA-69202
Class I MHC mediated antigen processing & presentation R-HSA-983169
RAF/MAP kinase cascade R-HSA-5673001
Host Interactions of HIV factors R-HSA-162909
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
S Phase R-HSA-69242
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Transition R-HSA-69275
Hedgehog 'on' state R-HSA-5632684
Orc1 removal from chromatin R-HSA-68949
MAPK family signaling cascades R-HSA-5683057
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S DNA Damage Checkpoints R-HSA-69615
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signal Transduction R-HSA-162582
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stimuli R-HSA-8953897
Neddylation R-HSA-8951664
Vif-mediated degradation of APOBEC3G R-HSA-180585
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of amino acids and derivatives R-HSA-71291
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI1 by the proteasome R-HSA-5610780
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX2 R-HSA-8878166
Ub-specific processing proteases R-HSA-5689880
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of expression of SLITs and ROBOs R-HSA-9010553
KEAP1-NFE2L2 pathway R-HSA-9755511
Disease R-HSA-1643685
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of DVL R-HSA-4641258
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
PIP3 activates AKT signaling R-HSA-1257604
Deubiquitination R-HSA-5688426
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic Anaphase R-HSA-68882
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cytokine Signaling in Immune system R-HSA-1280215
Synthesis of DNA R-HSA-69239
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of RUNX2 expression and activity R-HSA-8939902
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Generic Transcription Pathway R-HSA-212436
DNA Replication Pre-Initiation R-HSA-69002
Signaling by Interleukins R-HSA-449147
Mitotic G2-G2/M phases R-HSA-453274
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Downstream TCR signaling R-HSA-202424
Separation of Sister Chromatids R-HSA-2467813
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX3 R-HSA-8878159
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
DNA Replication R-HSA-69306
Axon guidance R-HSA-422475
Cellular response to chemical stress R-HSA-9711123
Interleukin-1 signaling R-HSA-9020702
M Phase R-HSA-68886
Metabolism of polyamines R-HSA-351202
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to hypoxia R-HSA-1234174
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of proteins R-HSA-392499
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Interleukin-1 family signaling R-HSA-446652
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle R-HSA-1640170
Metabolism R-HSA-1430728
UCH proteinases R-HSA-5689603
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Switching of origins to a post-replicative state R-HSA-69052
PTEN Regulation R-HSA-6807070
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle Checkpoints R-HSA-69620
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transport of small molecules R-HSA-382551
RNA Polymerase II Transcription R-HSA-73857
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by WNT R-HSA-195721
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by NOTCH4 R-HSA-9013694
Regulation of Apoptosis R-HSA-169911
G2/M Checkpoints R-HSA-69481
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of GLI2 by the proteasome R-HSA-5610783
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by ROBO receptors R-HSA-376176
Regulation of RAS by GAPs R-HSA-5658442
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
HIV Infection R-HSA-162906
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by NOTCH R-HSA-157118
Stabilization of p53 R-HSA-69541
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic G1 phase and G1/S transition R-HSA-453279
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
ABC transporter disorders R-HSA-5619084
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of AXIN R-HSA-4641257
Hh mutants are degraded by ERAD R-HSA-5362768
Immune System R-HSA-168256
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing-Cross presentation R-HSA-1236975
MAPK6/MAPK4 signaling R-HSA-5687128
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of RNA R-HSA-8953854
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
PCP/CE pathway R-HSA-4086400
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Innate Immune System R-HSA-168249
TCR signaling R-HSA-202403
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog 'off' state R-HSA-5610787
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by Hedgehog R-HSA-5358351
CLEC7A (Dectin-1) signaling R-HSA-5607764
Apoptosis R-HSA-109581
Adaptive Immune System R-HSA-1280218
ER-Phagosome pathway R-HSA-1236974
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of Apoptosis R-HSA-169911
Mitotic G2-G2/M phases R-HSA-453274
Regulation of mitotic cell cycle R-HSA-453276
Signal Transduction R-HSA-162582
Disorders of transmembrane transporters R-HSA-5619115
Cellular responses to stimuli R-HSA-8953897
Degradation of beta-catenin by the destruction complex R-HSA-195253
Class I MHC mediated antigen processing & presentation R-HSA-983169
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of RUNX2 expression and activity R-HSA-8939902
Cellular response to hypoxia R-HSA-1234174
Cellular response to chemical stress R-HSA-9711123
M Phase R-HSA-68886
G2/M Checkpoints R-HSA-69481
KEAP1-NFE2L2 pathway R-HSA-9755511
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1 DNA Damage Response R-HSA-69563
Intracellular signaling by second messengers R-HSA-9006925
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of polyamines R-HSA-351202
G1/S Transition R-HSA-69206
RNA Polymerase II Transcription R-HSA-73857
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
S Phase R-HSA-69242
Degradation of GLI1 by the proteasome R-HSA-5610780
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Ub-specific processing proteases R-HSA-5689880
Hh mutants are degraded by ERAD R-HSA-5362768
Post-translational protein modification R-HSA-597592
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Immune System R-HSA-168256
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH R-HSA-157118
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by WNT R-HSA-195721
TCR signaling R-HSA-202403
Downstream TCR signaling R-HSA-202424
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by NOTCH4 R-HSA-9013694
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of DVL R-HSA-4641258
G2/M Transition R-HSA-69275
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle R-HSA-1640170
Apoptosis R-HSA-109581
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Separation of Sister Chromatids R-HSA-2467813
Programmed Cell Death R-HSA-5357801
Interleukin-1 family signaling R-HSA-446652
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle Checkpoints R-HSA-69620
Signaling by ROBO receptors R-HSA-376176
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Interleukin-1 signaling R-HSA-9020702
Generic Transcription Pathway R-HSA-212436
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog ligand biogenesis R-HSA-5358346
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of PTEN stability and activity R-HSA-8948751
Assembly of the pre-replicative complex R-HSA-68867
Mitotic Anaphase R-HSA-68882
Neddylation R-HSA-8951664
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX1 R-HSA-8878171
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX2 R-HSA-8878166
Axon guidance R-HSA-422475
PTEN Regulation R-HSA-6807070
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vif-mediated degradation of APOBEC3G R-HSA-180585
Asymmetric localization of PCP proteins R-HSA-4608870
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Defective CFTR causes cystic fibrosis R-HSA-5678895
Nervous system development R-HSA-9675108
Antigen processing-Cross presentation R-HSA-1236975
Transcriptional regulation by RUNX3 R-HSA-8878159
Disease R-HSA-1643685
Vpu mediated degradation of CD4 R-HSA-180534
Negative regulation of NOTCH4 signaling R-HSA-9604323
C-type lectin receptors (CLRs) R-HSA-5621481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Beta-catenin independent WNT signaling R-HSA-3858494
ABC-family proteins mediated transport R-HSA-382556
Transport of small molecules R-HSA-382551
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
DNA Replication R-HSA-69306
Nuclear events mediated by NFE2L2 R-HSA-9759194
ABC transporter disorders R-HSA-5619084
MAPK1/MAPK3 signaling R-HSA-5684996
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by Interleukins R-HSA-449147
Deubiquitination R-HSA-5688426
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cyclin E associated events during G1/S transition R-HSA-69202
Orc1 removal from chromatin R-HSA-68949
DNA Replication Pre-Initiation R-HSA-69002
Adaptive Immune System R-HSA-1280218
Regulation of RUNX3 expression and activity R-HSA-8941858
PCP/CE pathway R-HSA-4086400
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK6/MAPK4 signaling R-HSA-5687128
Metabolism of RNA R-HSA-8953854
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Metabolism of proteins R-HSA-392499
Degradation of AXIN R-HSA-4641257
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Gene expression (Transcription) R-HSA-74160
Host Interactions of HIV factors R-HSA-162909
Infectious disease R-HSA-5663205
Developmental Biology R-HSA-1266738
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Stabilization of p53 R-HSA-69541
Hedgehog 'on' state R-HSA-5632684
Innate Immune System R-HSA-168249
HIV Infection R-HSA-162906
Activation of NF-kappaB in B cells R-HSA-1169091
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RAF/MAP kinase cascade R-HSA-5673001
Synthesis of DNA R-HSA-69239
Switching of origins to a post-replicative state R-HSA-69052
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Independent DNA Damage Response R-HSA-69610
UCH proteinases R-HSA-5689603
Metabolism R-HSA-1430728
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RUNX2 expression and activity R-HSA-8939902
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of AXIN R-HSA-4641257
Regulation of Apoptosis R-HSA-169911
DNA Replication Pre-Initiation R-HSA-69002
Mitotic Anaphase R-HSA-68882
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
UCH proteinases R-HSA-5689603
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
M Phase R-HSA-68886
PCP/CE pathway R-HSA-4086400
C-type lectin receptors (CLRs) R-HSA-5621481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Hedgehog 'on' state R-HSA-5632684
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of GLI2 by the proteasome R-HSA-5610783
Cell Cycle, Mitotic R-HSA-69278
G2/M Transition R-HSA-69275
Mitotic G2-G2/M phases R-HSA-453274
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hh mutants abrogate ligand secretion R-HSA-5387390
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transcriptional regulation by RUNX1 R-HSA-8878171
Transport of small molecules R-HSA-382551
Innate Immune System R-HSA-168249
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Metaphase and Anaphase R-HSA-2555396
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of RUNX3 expression and activity R-HSA-8941858
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Orc1 removal from chromatin R-HSA-68949
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Programmed Cell Death R-HSA-5357801
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH R-HSA-157118
Developmental Biology R-HSA-1266738
Cell Cycle R-HSA-1640170
Apoptosis R-HSA-109581
Cellular responses to stress R-HSA-2262752
Metabolism of RNA R-HSA-8953854
Asymmetric localization of PCP proteins R-HSA-4608870
Adaptive Immune System R-HSA-1280218
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Signaling by NOTCH4 R-HSA-9013694
CLEC7A (Dectin-1) signaling R-HSA-5607764
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog ligand biogenesis R-HSA-5358346
HIV Infection R-HSA-162906
Cellular response to chemical stress R-HSA-9711123
Synthesis of DNA R-HSA-69239
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
S Phase R-HSA-69242
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by WNT R-HSA-195721
Metabolism of proteins R-HSA-392499
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular responses to stimuli R-HSA-8953897
Axon guidance R-HSA-422475
Mitotic G1 phase and G1/S transition R-HSA-453279
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of mitotic cell cycle R-HSA-453276
Class I MHC mediated antigen processing & presentation R-HSA-983169
Nervous system development R-HSA-9675108
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Immune System R-HSA-168256
Signaling by ROBO receptors R-HSA-376176
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of DVL R-HSA-4641258
Neddylation R-HSA-8951664
Host Interactions of HIV factors R-HSA-162909
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Independent DNA Damage Response R-HSA-69610
FCERI mediated NF-kB activation R-HSA-2871837
MAPK1/MAPK3 signaling R-HSA-5684996
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Vpu mediated degradation of CD4 R-HSA-180534
Stabilization of p53 R-HSA-69541
Assembly of the pre-replicative complex R-HSA-68867
Activation of NF-kappaB in B cells R-HSA-1169091
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of GLI1 by the proteasome R-HSA-5610780
Post-translational protein modification R-HSA-597592
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Downstream TCR signaling R-HSA-202424
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
DNA Replication R-HSA-69306
Signaling by Interleukins R-HSA-449147
G2/M Checkpoints R-HSA-69481
Separation of Sister Chromatids R-HSA-2467813
Metabolism of amino acids and derivatives R-HSA-71291
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Negative regulation of NOTCH4 signaling R-HSA-9604323
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Antigen processing-Cross presentation R-HSA-1236975
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transcriptional regulation by RUNX3 R-HSA-8878159
RAF/MAP kinase cascade R-HSA-5673001
Defective CFTR causes cystic fibrosis R-HSA-5678895
Disease R-HSA-1643685
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
ER-Phagosome pathway R-HSA-1236974
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G1/S DNA Damage Checkpoints R-HSA-69615
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX2 R-HSA-8878166
Hh mutants are degraded by ERAD R-HSA-5362768
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of polyamines R-HSA-351202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Switching of origins to a post-replicative state R-HSA-69052
PTEN Regulation R-HSA-6807070
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ABC transporter disorders R-HSA-5619084
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism R-HSA-1430728
Cell Cycle Checkpoints R-HSA-69620
TCF dependent signaling in response to WNT R-HSA-201681
TCR signaling R-HSA-202403
Signaling by Hedgehog R-HSA-5358351
Generic Transcription Pathway R-HSA-212436
MAPK family signaling cascades R-HSA-5683057
Interleukin-1 family signaling R-HSA-446652
Disorders of transmembrane transporters R-HSA-5619115
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX1 R-HSA-8878171
Deubiquitination R-HSA-5688426
Innate Immune System R-HSA-168249
Stabilization of p53 R-HSA-69541
Gene expression (Transcription) R-HSA-74160
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Apoptosis R-HSA-109581
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
MAPK6/MAPK4 signaling R-HSA-5687128
Interleukin-1 signaling R-HSA-9020702
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
DNA Replication R-HSA-69306
Ub-specific processing proteases R-HSA-5689880
Infectious disease R-HSA-5663205
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PIP3 activates AKT signaling R-HSA-1257604
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
M Phase R-HSA-68886
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by Interleukins R-HSA-449147
Mitotic G2-G2/M phases R-HSA-453274
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of AXIN R-HSA-4641257
Cell Cycle, Mitotic R-HSA-69278
Regulation of Apoptosis R-HSA-169911
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by NOTCH4 R-HSA-9013694
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hh mutants are degraded by ERAD R-HSA-5362768
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX2 R-HSA-8878166
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism R-HSA-1430728
Nuclear events mediated by NFE2L2 R-HSA-9759194
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by WNT R-HSA-195721
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle Checkpoints R-HSA-69620
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Independent DNA Damage Response R-HSA-69610
Signaling by ROBO receptors R-HSA-376176
Disorders of transmembrane transporters R-HSA-5619115
DNA Replication Pre-Initiation R-HSA-69002
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular responses to stress R-HSA-2262752
PTEN Regulation R-HSA-6807070
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Class I MHC mediated antigen processing & presentation R-HSA-983169
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PCP/CE pathway R-HSA-4086400
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular responses to stimuli R-HSA-8953897
Mitotic Anaphase R-HSA-68882
Host Interactions of HIV factors R-HSA-162909
Metabolism of polyamines R-HSA-351202
RAF/MAP kinase cascade R-HSA-5673001
Neddylation R-HSA-8951664
C-type lectin receptors (CLRs) R-HSA-5621481
Axon guidance R-HSA-422475
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Vpu mediated degradation of CD4 R-HSA-180534
TCR signaling R-HSA-202403
Regulation of mitotic cell cycle R-HSA-453276
Cytokine Signaling in Immune system R-HSA-1280215
RNA Polymerase II Transcription R-HSA-73857
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog 'off' state R-HSA-5610787
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Hedgehog R-HSA-5358351
Signaling by NOTCH R-HSA-157118
Transport of small molecules R-HSA-382551
Nervous system development R-HSA-9675108
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
KEAP1-NFE2L2 pathway R-HSA-9755511
Orc1 removal from chromatin R-HSA-68949
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Programmed Cell Death R-HSA-5357801
Degradation of DVL R-HSA-4641258
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of amino acids and derivatives R-HSA-71291
Developmental Biology R-HSA-1266738
S Phase R-HSA-69242
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Downstream TCR signaling R-HSA-202424
Disease R-HSA-1643685
Regulation of RUNX2 expression and activity R-HSA-8939902
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
G1/S DNA Damage Checkpoints R-HSA-69615
Generic Transcription Pathway R-HSA-212436
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cellular response to hypoxia R-HSA-1234174
Immune System R-HSA-168256
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
FCERI mediated NF-kB activation R-HSA-2871837
Switching of origins to a post-replicative state R-HSA-69052
Cell Cycle R-HSA-1640170
Metabolism of proteins R-HSA-392499
Hedgehog 'on' state R-HSA-5632684
Post-translational protein modification R-HSA-597592
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Transition R-HSA-69275
TCF dependent signaling in response to WNT R-HSA-201681
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Antigen processing-Cross presentation R-HSA-1236975
Assembly of the pre-replicative complex R-HSA-68867
ABC transporter disorders R-HSA-5619084
ABC-family proteins mediated transport R-HSA-382556
Degradation of GLI1 by the proteasome R-HSA-5610780
Cellular response to chemical stress R-HSA-9711123
Regulation of RAS by GAPs R-HSA-5658442
UCH proteinases R-HSA-5689603
G1/S Transition R-HSA-69206
Signal Transduction R-HSA-162582
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 family signaling R-HSA-446652
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX3 R-HSA-8878159
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of GLI2 by the proteasome R-HSA-5610783
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Metabolism of RNA R-HSA-8953854
ER-Phagosome pathway R-HSA-1236974
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic G1 phase and G1/S transition R-HSA-453279
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Dependent G1 DNA Damage Response R-HSA-69563
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Synthesis of DNA R-HSA-69239
Cell Cycle Checkpoints R-HSA-69620
Downstream TCR signaling R-HSA-202424
Regulation of RUNX3 expression and activity R-HSA-8941858
Interleukin-1 family signaling R-HSA-446652
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Assembly of the pre-replicative complex R-HSA-68867
ABC transporter disorders R-HSA-5619084
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Apoptosis R-HSA-109581
RNA Polymerase II Transcription R-HSA-73857
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Innate Immune System R-HSA-168249
Mitotic Metaphase and Anaphase R-HSA-2555396
Vif-mediated degradation of APOBEC3G R-HSA-180585
Gene expression (Transcription) R-HSA-74160
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing-Cross presentation R-HSA-1236975
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ABC-family proteins mediated transport R-HSA-382556
Disorders of transmembrane transporters R-HSA-5619115
Ub-specific processing proteases R-HSA-5689880
Post-translational protein modification R-HSA-597592
Cell Cycle R-HSA-1640170
Regulation of mitotic cell cycle R-HSA-453276
Immune System R-HSA-168256
MAPK family signaling cascades R-HSA-5683057
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
C-type lectin receptors (CLRs) R-HSA-5621481
Metabolism of RNA R-HSA-8953854
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
M Phase R-HSA-68886
Transport of small molecules R-HSA-382551
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Vpu mediated degradation of CD4 R-HSA-180534
G1/S DNA Damage Checkpoints R-HSA-69615
Intracellular signaling by second messengers R-HSA-9006925
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hh mutants abrogate ligand secretion R-HSA-5387390
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cyclin E associated events during G1/S transition R-HSA-69202
Hedgehog ligand biogenesis R-HSA-5358346
Neddylation R-HSA-8951664
RAF/MAP kinase cascade R-HSA-5673001
Axon guidance R-HSA-422475
Cellular responses to stimuli R-HSA-8953897
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic G2-G2/M phases R-HSA-453274
MAPK1/MAPK3 signaling R-HSA-5684996
ER-Phagosome pathway R-HSA-1236974
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
PTEN Regulation R-HSA-6807070
Class I MHC mediated antigen processing & presentation R-HSA-983169
PIP3 activates AKT signaling R-HSA-1257604
HIV Infection R-HSA-162906
Signaling by WNT R-HSA-195721
G2/M Checkpoints R-HSA-69481
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Disease R-HSA-1643685
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of Apoptosis R-HSA-169911
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Deubiquitination R-HSA-5688426
Nervous system development R-HSA-9675108
Activation of NF-kappaB in B cells R-HSA-1169091
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of AXIN R-HSA-4641257
Regulation of PTEN stability and activity R-HSA-8948751
Cell Cycle, Mitotic R-HSA-69278
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Synthesis of DNA R-HSA-69239
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism R-HSA-1430728
Signaling by Interleukins R-HSA-449147
Signaling by NOTCH R-HSA-157118
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Anaphase R-HSA-68882
Stabilization of p53 R-HSA-69541
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PCP/CE pathway R-HSA-4086400
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
Infectious disease R-HSA-5663205
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Hedgehog R-HSA-5358351
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
DNA Replication R-HSA-69306
Signaling by NOTCH4 R-HSA-9013694
Defective CFTR causes cystic fibrosis R-HSA-5678895
Asymmetric localization of PCP proteins R-HSA-4608870
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by the B Cell Receptor (BCR) R-HSA-983705
DNA Replication Pre-Initiation R-HSA-69002
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX3 R-HSA-8878159
Cellular responses to stress R-HSA-2262752
Separation of Sister Chromatids R-HSA-2467813
Cellular response to chemical stress R-HSA-9711123
Degradation of beta-catenin by the destruction complex R-HSA-195253
G2/M Transition R-HSA-69275
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of DVL R-HSA-4641258
Hedgehog 'on' state R-HSA-5632684
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 signaling R-HSA-9020702
NIK-->noncanonical NF-kB signaling R-HSA-5676590
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by ROBO receptors R-HSA-376176
Metabolism of polyamines R-HSA-351202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Host Interactions of HIV factors R-HSA-162909
Transcriptional regulation by RUNX1 R-HSA-8878171
Orc1 removal from chromatin R-HSA-68949
UCH proteinases R-HSA-5689603
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TCR signaling R-HSA-202403
FCERI mediated NF-kB activation R-HSA-2871837
Negative regulation of NOTCH4 signaling R-HSA-9604323
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Adaptive Immune System R-HSA-1280218
CLEC7A (Dectin-1) signaling R-HSA-5607764
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Programmed Cell Death R-HSA-5357801
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism of proteins R-HSA-392499
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Dependent G1 DNA Damage Response R-HSA-69563
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of amino acids and derivatives R-HSA-71291
Cellular response to hypoxia R-HSA-1234174
Nuclear events mediated by NFE2L2 R-HSA-9759194
Neddylation R-HSA-8951664
Hedgehog 'on' state R-HSA-5632684
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of RAS by GAPs R-HSA-5658442
DNA Replication R-HSA-69306
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCF dependent signaling in response to WNT R-HSA-201681
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Interleukins R-HSA-449147
Cyclin E associated events during G1/S transition R-HSA-69202
Infectious disease R-HSA-5663205
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transcriptional regulation by RUNX2 R-HSA-8878166
Negative regulation of NOTCH4 signaling R-HSA-9604323
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hh mutants are degraded by ERAD R-HSA-5362768
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle, Mitotic R-HSA-69278
PCP/CE pathway R-HSA-4086400
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of GLI1 by the proteasome R-HSA-5610780
Stabilization of p53 R-HSA-69541
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of Apoptosis R-HSA-169911
Metabolism of polyamines R-HSA-351202
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX3 R-HSA-8878159
Transport of small molecules R-HSA-382551
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic G2-G2/M phases R-HSA-453274
G2/M Transition R-HSA-69275
Switching of origins to a post-replicative state R-HSA-69052
Downstream TCR signaling R-HSA-202424
ABC transporter disorders R-HSA-5619084
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
ER-Phagosome pathway R-HSA-1236974
Innate Immune System R-HSA-168249
Post-translational protein modification R-HSA-597592
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK family signaling cascades R-HSA-5683057
Mitotic G1 phase and G1/S transition R-HSA-453279
G2/M Checkpoints R-HSA-69481
Regulation of RUNX2 expression and activity R-HSA-8939902
Cytokine Signaling in Immune system R-HSA-1280215
Orc1 removal from chromatin R-HSA-68949
S Phase R-HSA-69242
C-type lectin receptors (CLRs) R-HSA-5621481
M Phase R-HSA-68886
Beta-catenin independent WNT signaling R-HSA-3858494
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Antigen processing-Cross presentation R-HSA-1236975
p53-Independent DNA Damage Response R-HSA-69610
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Synthesis of DNA R-HSA-69239
DNA Replication Pre-Initiation R-HSA-69002
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
Interleukin-1 family signaling R-HSA-446652
Signaling by WNT R-HSA-195721
Asymmetric localization of PCP proteins R-HSA-4608870
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Disorders of transmembrane transporters R-HSA-5619115
KEAP1-NFE2L2 pathway R-HSA-9755511
Deubiquitination R-HSA-5688426
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by NOTCH R-HSA-157118
Degradation of AXIN R-HSA-4641257
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle Checkpoints R-HSA-69620
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Axon guidance R-HSA-422475
Intracellular signaling by second messengers R-HSA-9006925
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Adaptive Immune System R-HSA-1280218
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of proteins R-HSA-392499
Nervous system development R-HSA-9675108
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of RNA R-HSA-8953854
Cellular responses to stimuli R-HSA-8953897
Degradation of DVL R-HSA-4641258
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic Anaphase R-HSA-68882
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1 DNA Damage Response R-HSA-69563
FCERI mediated NF-kB activation R-HSA-2871837
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog ligand biogenesis R-HSA-5358346
RAF/MAP kinase cascade R-HSA-5673001
Regulation of PTEN stability and activity R-HSA-8948751
Developmental Biology R-HSA-1266738
Cellular response to chemical stress R-HSA-9711123
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Apoptosis R-HSA-109581
Immune System R-HSA-168256
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle R-HSA-1640170
TCR signaling R-HSA-202403
Signaling by the B Cell Receptor (BCR) R-HSA-983705
HIV Infection R-HSA-162906
Regulation of RUNX3 expression and activity R-HSA-8941858
PTEN Regulation R-HSA-6807070
Metabolism R-HSA-1430728
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Ub-specific processing proteases R-HSA-5689880
Signaling by Hedgehog R-HSA-5358351
Regulation of mitotic cell cycle R-HSA-453276
Signaling by NOTCH4 R-HSA-9013694
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
UCH proteinases R-HSA-5689603
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signal Transduction R-HSA-162582
Signaling by ROBO receptors R-HSA-376176
PIP3 activates AKT signaling R-HSA-1257604
Separation of Sister Chromatids R-HSA-2467813
Vif-mediated degradation of APOBEC3G R-HSA-180585
Host Interactions of HIV factors R-HSA-162909
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of amino acids and derivatives R-HSA-71291
Programmed Cell Death R-HSA-5357801
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RUNX2 expression and activity R-HSA-8939902
CLEC7A (Dectin-1) signaling R-HSA-5607764
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by ROBO receptors R-HSA-376176
ABC-family proteins mediated transport R-HSA-382556
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cyclin E associated events during G1/S transition R-HSA-69202
PIP3 activates AKT signaling R-HSA-1257604
Transport of small molecules R-HSA-382551
Downstream TCR signaling R-HSA-202424
p53-Independent DNA Damage Response R-HSA-69610
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of beta-catenin by the destruction complex R-HSA-195253
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cytokine Signaling in Immune system R-HSA-1280215
Cellular response to chemical stress R-HSA-9711123
Immune System R-HSA-168256
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX2 R-HSA-8878166
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Orc1 removal from chromatin R-HSA-68949
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RAS by GAPs R-HSA-5658442
G2/M Transition R-HSA-69275
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism R-HSA-1430728
Hedgehog ligand biogenesis R-HSA-5358346
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Infectious disease R-HSA-5663205
MAPK6/MAPK4 signaling R-HSA-5687128
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Interleukin-1 family signaling R-HSA-446652
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of DVL R-HSA-4641258
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
Signaling by NOTCH R-HSA-157118
Negative regulation of NOTCH4 signaling R-HSA-9604323
Interleukin-1 signaling R-HSA-9020702
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of polyamines R-HSA-351202
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hedgehog 'off' state R-HSA-5610787
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism of amino acids and derivatives R-HSA-71291
G1/S Transition R-HSA-69206
TCR signaling R-HSA-202403
Cellular responses to stress R-HSA-2262752
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
Disease R-HSA-1643685
G2/M Checkpoints R-HSA-69481
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
ABC transporter disorders R-HSA-5619084
Separation of Sister Chromatids R-HSA-2467813
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G1 phase and G1/S transition R-HSA-453279
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Programmed Cell Death R-HSA-5357801
M Phase R-HSA-68886
Signaling by Interleukins R-HSA-449147
Generic Transcription Pathway R-HSA-212436
Cellular response to hypoxia R-HSA-1234174
Post-translational protein modification R-HSA-597592
Assembly of the pre-replicative complex R-HSA-68867
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX1 R-HSA-8878171
Neddylation R-HSA-8951664
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of RUNX3 expression and activity R-HSA-8941858
RNA Polymerase II Transcription R-HSA-73857
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
Deubiquitination R-HSA-5688426
Mitotic Anaphase R-HSA-68882
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Host Interactions of HIV factors R-HSA-162909
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication R-HSA-69306
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Synthesis of DNA R-HSA-69239
Cell Cycle Checkpoints R-HSA-69620
NIK-->noncanonical NF-kB signaling R-HSA-5676590
UCH proteinases R-HSA-5689603
Regulation of PTEN stability and activity R-HSA-8948751
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
PCP/CE pathway R-HSA-4086400
Antigen processing-Cross presentation R-HSA-1236975
Asymmetric localization of PCP proteins R-HSA-4608870
Apoptosis R-HSA-109581
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Innate Immune System R-HSA-168249
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular responses to stimuli R-HSA-8953897
Vpu mediated degradation of CD4 R-HSA-180534
Transcriptional regulation by RUNX3 R-HSA-8878159
Intracellular signaling by second messengers R-HSA-9006925
FCERI mediated NF-kB activation R-HSA-2871837
MAPK family signaling cascades R-HSA-5683057
Degradation of GLI2 by the proteasome R-HSA-5610783
Beta-catenin independent WNT signaling R-HSA-3858494
HIV Infection R-HSA-162906
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle R-HSA-1640170
Axon guidance R-HSA-422475
S Phase R-HSA-69242
Signaling by WNT R-HSA-195721
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of RNA R-HSA-8953854
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of Apoptosis R-HSA-169911
DNA Replication Pre-Initiation R-HSA-69002
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Developmental Biology R-HSA-1266738
Regulation of mitotic cell cycle R-HSA-453276
Disorders of transmembrane transporters R-HSA-5619115
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Stabilization of p53 R-HSA-69541
Switching of origins to a post-replicative state R-HSA-69052
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of AXIN R-HSA-4641257
Vif-mediated degradation of APOBEC3G R-HSA-180585
Defective CFTR causes cystic fibrosis R-HSA-5678895
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
C-type lectin receptors (CLRs) R-HSA-5621481
PTEN Regulation R-HSA-6807070
Adaptive Immune System R-HSA-1280218
Signaling by NOTCH4 R-HSA-9013694
Signal Transduction R-HSA-162582
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transcriptional regulation by RUNX2 R-HSA-8878166
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by NOTCH R-HSA-157118
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cyclin E associated events during G1/S transition R-HSA-69202
Activation of NF-kappaB in B cells R-HSA-1169091
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Disease R-HSA-1643685
Asymmetric localization of PCP proteins R-HSA-4608870
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by WNT R-HSA-195721
Signal Transduction R-HSA-162582
Cellular responses to stimuli R-HSA-8953897
MAPK6/MAPK4 signaling R-HSA-5687128
Cytokine Signaling in Immune system R-HSA-1280215
G2/M Transition R-HSA-69275
ABC-family proteins mediated transport R-HSA-382556
DNA Replication R-HSA-69306
Regulation of RAS by GAPs R-HSA-5658442
Regulation of RUNX2 expression and activity R-HSA-8939902
Stabilization of p53 R-HSA-69541
ABC transporter disorders R-HSA-5619084
Programmed Cell Death R-HSA-5357801
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Independent DNA Damage Response R-HSA-69610
Innate Immune System R-HSA-168249
Signaling by ROBO receptors R-HSA-376176
Ub-specific processing proteases R-HSA-5689880
Beta-catenin independent WNT signaling R-HSA-3858494
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Synthesis of DNA R-HSA-69239
Signaling by Hedgehog R-HSA-5358351
KEAP1-NFE2L2 pathway R-HSA-9755511
DNA Replication Pre-Initiation R-HSA-69002
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
TCR signaling R-HSA-202403
Defective CFTR causes cystic fibrosis R-HSA-5678895
Apoptosis R-HSA-109581
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 family signaling R-HSA-446652
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI1 by the proteasome R-HSA-5610780
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular response to chemical stress R-HSA-9711123
Degradation of AXIN R-HSA-4641257
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Post-translational protein modification R-HSA-597592
G1/S DNA Damage Checkpoints R-HSA-69615
MAPK family signaling cascades R-HSA-5683057
Regulation of RUNX3 expression and activity R-HSA-8941858
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular responses to stress R-HSA-2262752
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle, Mitotic R-HSA-69278
Hedgehog 'on' state R-HSA-5632684
RAF/MAP kinase cascade R-HSA-5673001
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Intracellular signaling by second messengers R-HSA-9006925
M Phase R-HSA-68886
Immune System R-HSA-168256
Gene expression (Transcription) R-HSA-74160
S Phase R-HSA-69242
Adaptive Immune System R-HSA-1280218
G2/M Checkpoints R-HSA-69481
Negative regulation of NOTCH4 signaling R-HSA-9604323
RNA Polymerase II Transcription R-HSA-73857
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
HIV Infection R-HSA-162906
Cell Cycle R-HSA-1640170
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Interleukins R-HSA-449147
CLEC7A (Dectin-1) signaling R-HSA-5607764
ER-Phagosome pathway R-HSA-1236974
Transcriptional regulation by RUNX3 R-HSA-8878159
Downstream TCR signaling R-HSA-202424
Metabolism of polyamines R-HSA-351202
Regulation of PTEN stability and activity R-HSA-8948751
Infectious disease R-HSA-5663205
Interleukin-1 signaling R-HSA-9020702
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of mitotic cell cycle R-HSA-453276
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PTEN Regulation R-HSA-6807070
Class I MHC mediated antigen processing & presentation R-HSA-983169
Generic Transcription Pathway R-HSA-212436
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Orc1 removal from chromatin R-HSA-68949
FCERI mediated NF-kB activation R-HSA-2871837
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Deubiquitination R-HSA-5688426
UCH proteinases R-HSA-5689603
Mitotic G1 phase and G1/S transition R-HSA-453279
Developmental Biology R-HSA-1266738
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hedgehog 'off' state R-HSA-5610787
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Separation of Sister Chromatids R-HSA-2467813
Degradation of DVL R-HSA-4641258
Metabolism of RNA R-HSA-8953854
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of proteins R-HSA-392499
Metabolism of amino acids and derivatives R-HSA-71291
PCP/CE pathway R-HSA-4086400
Transport of small molecules R-HSA-382551
Vpu mediated degradation of CD4 R-HSA-180534
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic G2-G2/M phases R-HSA-453274
Neddylation R-HSA-8951664
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism R-HSA-1430728
Assembly of the pre-replicative complex R-HSA-68867
Antigen processing-Cross presentation R-HSA-1236975
Nervous system development R-HSA-9675108
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
C-type lectin receptors (CLRs) R-HSA-5621481
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Host Interactions of HIV factors R-HSA-162909
Disorders of transmembrane transporters R-HSA-5619115
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Switching of origins to a post-replicative state R-HSA-69052
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle Checkpoints R-HSA-69620
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Mitotic Anaphase R-HSA-68882
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Dependent G1 DNA Damage Response R-HSA-69563
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX1 R-HSA-8878171
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of beta-catenin by the destruction complex R-HSA-195253
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hh mutants abrogate ligand secretion R-HSA-5387390
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of Apoptosis R-HSA-169911
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
RNA Polymerase II Transcription R-HSA-73857
Orc1 removal from chromatin R-HSA-68949
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Nuclear events mediated by NFE2L2 R-HSA-9759194
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of AXIN R-HSA-4641257
Cell Cycle R-HSA-1640170
UCH proteinases R-HSA-5689603
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog 'on' state R-HSA-5632684
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of GLI1 by the proteasome R-HSA-5610780
Stabilization of p53 R-HSA-69541
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Class I MHC mediated antigen processing & presentation R-HSA-983169
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by ROBO receptors R-HSA-376176
TCR signaling R-HSA-202403
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular response to hypoxia R-HSA-1234174
Asymmetric localization of PCP proteins R-HSA-4608870
Switching of origins to a post-replicative state R-HSA-69052
DNA Replication Pre-Initiation R-HSA-69002
ABC transporter disorders R-HSA-5619084
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Infectious disease R-HSA-5663205
Metabolism of RNA R-HSA-8953854
Signaling by Hedgehog R-HSA-5358351
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
DNA Replication R-HSA-69306
PIP3 activates AKT signaling R-HSA-1257604
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
PTEN Regulation R-HSA-6807070
Synthesis of DNA R-HSA-69239
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Post-translational protein modification R-HSA-597592
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to chemical stress R-HSA-9711123
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signal Transduction R-HSA-162582
Neddylation R-HSA-8951664
Ub-specific processing proteases R-HSA-5689880
Metabolism R-HSA-1430728
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Transcriptional regulation by RUNX1 R-HSA-8878171
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle, Mitotic R-HSA-69278
Signaling by NOTCH R-HSA-157118
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hedgehog ligand biogenesis R-HSA-5358346
Programmed Cell Death R-HSA-5357801
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by WNT R-HSA-195721
Disorders of transmembrane transporters R-HSA-5619115
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Mitotic Anaphase R-HSA-68882
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Transport of small molecules R-HSA-382551
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic Metaphase and Anaphase R-HSA-2555396
G1/S Transition R-HSA-69206
Interleukin-1 family signaling R-HSA-446652
Regulation of mitotic cell cycle R-HSA-453276
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of beta-catenin by the destruction complex R-HSA-195253
Separation of Sister Chromatids R-HSA-2467813
Regulation of RUNX3 expression and activity R-HSA-8941858
ER-Phagosome pathway R-HSA-1236974
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK1/MAPK3 signaling R-HSA-5684996
HIV Infection R-HSA-162906
Cellular responses to stimuli R-HSA-8953897
Hedgehog 'off' state R-HSA-5610787
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Downstream TCR signaling R-HSA-202424
Apoptosis R-HSA-109581
Intracellular signaling by second messengers R-HSA-9006925
Nervous system development R-HSA-9675108
Metabolism of proteins R-HSA-392499
Assembly of the pre-replicative complex R-HSA-68867
Developmental Biology R-HSA-1266738
Signaling by Interleukins R-HSA-449147
G2/M Checkpoints R-HSA-69481
CLEC7A (Dectin-1) signaling R-HSA-5607764
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of RAS by GAPs R-HSA-5658442
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX2 R-HSA-8878166
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
TCF dependent signaling in response to WNT R-HSA-201681
Cell Cycle Checkpoints R-HSA-69620
MAPK family signaling cascades R-HSA-5683057
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G1/S DNA Damage Checkpoints R-HSA-69615
Hh mutants abrogate ligand secretion R-HSA-5387390
Immune System R-HSA-168256
Regulation of Apoptosis R-HSA-169911
PCP/CE pathway R-HSA-4086400
Vif-mediated degradation of APOBEC3G R-HSA-180585
Gene expression (Transcription) R-HSA-74160
G2/M Transition R-HSA-69275
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Disease R-HSA-1643685
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Independent DNA Damage Response R-HSA-69610
Axon guidance R-HSA-422475
Mitotic G2-G2/M phases R-HSA-453274
RAF/MAP kinase cascade R-HSA-5673001
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stress R-HSA-2262752
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of DVL R-HSA-4641258
S Phase R-HSA-69242
Host Interactions of HIV factors R-HSA-162909
Adaptive Immune System R-HSA-1280218
Deubiquitination R-HSA-5688426
Innate Immune System R-HSA-168249
Metabolism of polyamines R-HSA-351202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
M Phase R-HSA-68886
Transcriptional regulation by RUNX3 R-HSA-8878159
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202

Expression Atlas ENSG00000159377
NCBI gene (formerly Entrezgene) 5692
GeneCards 9541
HGNC Symbol HGNC:9541
MIM gene 602177
MIM morbid 617591
UniProtKB Gene Name P28070
WikiGene 5692