Gene: F7
Ensembl ID : ENSG00000057593
Description: coagulation factor VII
Gene Synonyms:
1 APIs:
203 Possible Orthologues:

Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Hemostasis R-HSA-109582
Gamma-carboxylation of protein precursors R-HSA-159740
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Circadian Clock R-HSA-400253
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Gamma-carboxylation of protein precursors R-HSA-159740
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Circadian Clock R-HSA-400253
Hemostasis R-HSA-109582
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Metabolism of proteins R-HSA-392499
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Post-translational protein modification R-HSA-597592
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Gamma-carboxylation of protein precursors R-HSA-159740
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Circadian Clock R-HSA-400253
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Post-translational protein modification R-HSA-597592
Hemostasis R-HSA-109582
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Metabolism of proteins R-HSA-392499
Gamma-carboxylation of protein precursors R-HSA-159740
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Hemostasis R-HSA-109582
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Post-translational protein modification R-HSA-597592
Circadian Clock R-HSA-400253
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Metabolism of proteins R-HSA-392499
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Post-translational protein modification R-HSA-597592
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Gamma-carboxylation of protein precursors R-HSA-159740
Circadian Clock R-HSA-400253
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Hemostasis R-HSA-109582
Metabolism of proteins R-HSA-392499
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Post-translational protein modification R-HSA-597592
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Hemostasis R-HSA-109582
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Circadian Clock R-HSA-400253
Gamma-carboxylation of protein precursors R-HSA-159740
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Metabolism of proteins R-HSA-392499
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Metabolism of proteins R-HSA-392499
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Post-translational protein modification R-HSA-597592
Circadian Clock R-HSA-400253
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Hemostasis R-HSA-109582
Gamma-carboxylation of protein precursors R-HSA-159740
Hemostasis R-HSA-109582
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Circadian Clock R-HSA-400253
Gamma-carboxylation of protein precursors R-HSA-159740
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Circadian Clock R-HSA-400253
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Hemostasis R-HSA-109582
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
BMAL1:CLOCK,NPAS2 activates circadian gene expression R-HSA-1368108
Gamma-carboxylation of protein precursors R-HSA-159740
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877

Expression Atlas ENSG00000057593
LRG display in Ensembl gene LRG_554
NCBI gene (formerly Entrezgene) 2155
GeneCards 3544
HGNC Symbol HGNC:3544
MIM gene 613878
MIM morbid 608446
UniProtKB Gene Name P08709
WikiGene 2155
Gene: ELANE
Ensembl ID : ENSG00000197561
Description: elastase, neutrophil expressed
Gene Synonyms: ELA2,HLE,HNE,NE,PMN-E
2 APIs:
91 Possible Orthologues:

Neutrophil degranulation R-HSA-6798695
Degradation of the extracellular matrix R-HSA-1474228
Innate Immune System R-HSA-168249
Pyroptosis R-HSA-5620971
Immune System R-HSA-168256
Activation of Matrix Metalloproteinases R-HSA-1592389
Programmed Cell Death R-HSA-5357801
Collagen degradation R-HSA-1442490
Antimicrobial peptides R-HSA-6803157
Regulation of Complement cascade R-HSA-977606
Extracellular matrix organization R-HSA-1474244
Complement cascade R-HSA-166658
Regulated Necrosis R-HSA-5218859
Neutrophil degranulation R-HSA-6798695
Antimicrobial peptides R-HSA-6803157
Immune System R-HSA-168256
Programmed Cell Death R-HSA-5357801
Complement cascade R-HSA-166658
Innate Immune System R-HSA-168249
Pyroptosis R-HSA-5620971
Regulated Necrosis R-HSA-5218859
Degradation of the extracellular matrix R-HSA-1474228
Regulation of Complement cascade R-HSA-977606
Extracellular matrix organization R-HSA-1474244
Activation of Matrix Metalloproteinases R-HSA-1592389
Collagen degradation R-HSA-1442490
Innate Immune System R-HSA-168249
Antimicrobial peptides R-HSA-6803157
Regulated Necrosis R-HSA-5218859
Collagen degradation R-HSA-1442490
Neutrophil degranulation R-HSA-6798695
Complement cascade R-HSA-166658
Regulation of Complement cascade R-HSA-977606
Degradation of the extracellular matrix R-HSA-1474228
Pyroptosis R-HSA-5620971
Programmed Cell Death R-HSA-5357801
Immune System R-HSA-168256
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Collagen degradation R-HSA-1442490
Regulation of Complement cascade R-HSA-977606
Pyroptosis R-HSA-5620971
Innate Immune System R-HSA-168249
Antimicrobial peptides R-HSA-6803157
Regulated Necrosis R-HSA-5218859
Extracellular matrix organization R-HSA-1474244
Activation of Matrix Metalloproteinases R-HSA-1592389
Degradation of the extracellular matrix R-HSA-1474228
Complement cascade R-HSA-166658
Programmed Cell Death R-HSA-5357801
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Complement cascade R-HSA-166658
Programmed Cell Death R-HSA-5357801
Antimicrobial peptides R-HSA-6803157
Innate Immune System R-HSA-168249
Degradation of the extracellular matrix R-HSA-1474228
Collagen degradation R-HSA-1442490
Regulated Necrosis R-HSA-5218859
Immune System R-HSA-168256
Pyroptosis R-HSA-5620971
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Regulation of Complement cascade R-HSA-977606
Neutrophil degranulation R-HSA-6798695
Activation of Matrix Metalloproteinases R-HSA-1592389
Programmed Cell Death R-HSA-5357801
Extracellular matrix organization R-HSA-1474244
Regulation of Complement cascade R-HSA-977606
Immune System R-HSA-168256
Regulated Necrosis R-HSA-5218859
Collagen degradation R-HSA-1442490
Degradation of the extracellular matrix R-HSA-1474228
Innate Immune System R-HSA-168249
Antimicrobial peptides R-HSA-6803157
Pyroptosis R-HSA-5620971
Complement cascade R-HSA-166658
Pyroptosis R-HSA-5620971
Regulated Necrosis R-HSA-5218859
Programmed Cell Death R-HSA-5357801
Complement cascade R-HSA-166658
Regulation of Complement cascade R-HSA-977606
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Antimicrobial peptides R-HSA-6803157
Activation of Matrix Metalloproteinases R-HSA-1592389
Degradation of the extracellular matrix R-HSA-1474228
Collagen degradation R-HSA-1442490
Extracellular matrix organization R-HSA-1474244
Neutrophil degranulation R-HSA-6798695
Regulated Necrosis R-HSA-5218859
Collagen degradation R-HSA-1442490
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Activation of Matrix Metalloproteinases R-HSA-1592389
Regulation of Complement cascade R-HSA-977606
Programmed Cell Death R-HSA-5357801
Complement cascade R-HSA-166658
Degradation of the extracellular matrix R-HSA-1474228
Extracellular matrix organization R-HSA-1474244
Innate Immune System R-HSA-168249
Antimicrobial peptides R-HSA-6803157
Pyroptosis R-HSA-5620971
Immune System R-HSA-168256
Complement cascade R-HSA-166658
Degradation of the extracellular matrix R-HSA-1474228
Collagen degradation R-HSA-1442490
Regulation of Complement cascade R-HSA-977606
Activation of Matrix Metalloproteinases R-HSA-1592389
Neutrophil degranulation R-HSA-6798695
Antimicrobial peptides R-HSA-6803157
Innate Immune System R-HSA-168249
Regulated Necrosis R-HSA-5218859
Extracellular matrix organization R-HSA-1474244
Pyroptosis R-HSA-5620971
Programmed Cell Death R-HSA-5357801

Expression Atlas ENSG00000197561
LRG display in Ensembl gene LRG_57
NCBI gene (formerly Entrezgene) 1991
GeneCards 3309
HGNC Symbol HGNC:3309
MIM gene 130130
MIM morbid 202700
UniProtKB Gene Name P08246
WikiGene 1991
Gene: F11
Ensembl ID : ENSG00000088926
Description: coagulation factor XI
Gene Synonyms: FXI
2 APIs:
215 Possible Orthologues:

Hemostasis R-HSA-109582
Diseases of hemostasis R-HSA-9671793
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Defective F9 activation R-HSA-9673221
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Disease R-HSA-1643685
Defective factor IX causes hemophilia B R-HSA-9668250
Defective F9 activation R-HSA-9673221
Disease R-HSA-1643685
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Diseases of hemostasis R-HSA-9671793
Defective factor IX causes hemophilia B R-HSA-9668250
Hemostasis R-HSA-109582
Defective F9 activation R-HSA-9673221
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Diseases of hemostasis R-HSA-9671793
Hemostasis R-HSA-109582
Defective factor IX causes hemophilia B R-HSA-9668250
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Disease R-HSA-1643685
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Diseases of hemostasis R-HSA-9671793
Defective factor IX causes hemophilia B R-HSA-9668250
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Disease R-HSA-1643685
Defective F9 activation R-HSA-9673221
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Hemostasis R-HSA-109582
Disease R-HSA-1643685
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defective factor IX causes hemophilia B R-HSA-9668250
Defective F9 activation R-HSA-9673221
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Diseases of hemostasis R-HSA-9671793
Hemostasis R-HSA-109582
Defective F9 activation R-HSA-9673221
Diseases of hemostasis R-HSA-9671793
Disease R-HSA-1643685
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Hemostasis R-HSA-109582
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defective factor IX causes hemophilia B R-HSA-9668250
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Disease R-HSA-1643685
Diseases of hemostasis R-HSA-9671793
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Defective F9 activation R-HSA-9673221
Hemostasis R-HSA-109582
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defective factor IX causes hemophilia B R-HSA-9668250
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Defective factor IX causes hemophilia B R-HSA-9668250
Defective F9 activation R-HSA-9673221
Hemostasis R-HSA-109582
Disease R-HSA-1643685
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Diseases of hemostasis R-HSA-9671793
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Diseases of hemostasis R-HSA-9671793
Disease R-HSA-1643685
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Hemostasis R-HSA-109582
Defective F9 activation R-HSA-9673221
Defective factor IX causes hemophilia B R-HSA-9668250
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defective factor IX causes hemophilia B R-HSA-9668250
Defective F9 activation R-HSA-9673221
Disease R-HSA-1643685
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Hemostasis R-HSA-109582
Diseases of hemostasis R-HSA-9671793
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877

Expression Atlas ENSG00000088926
LRG display in Ensembl gene LRG_583
NCBI gene (formerly Entrezgene) 2160
GeneCards 3529
HGNC Symbol HGNC:3529
MIM gene 264900
MIM morbid 612416
UniProtKB Gene Name P03951
WikiGene 2160
Gene: KLKB1
Ensembl ID : ENSG00000164344
Description: kallikrein B1
Gene Synonyms: KLK3
6 APIs:
209 Possible Orthologues:

Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Disease R-HSA-1643685
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Diseases of hemostasis R-HSA-9671793
Degradation of the extracellular matrix R-HSA-1474228
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Defective factor XII causes hereditary angioedema R-HSA-9657688
Hemostasis R-HSA-109582
Defective SERPING1 causes hereditary angioedema R-HSA-9657689
Extracellular matrix organization R-HSA-1474244
Activation of Matrix Metalloproteinases R-HSA-1592389
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defective factor XII causes hereditary angioedema R-HSA-9657688
Diseases of hemostasis R-HSA-9671793
Hemostasis R-HSA-109582
Defective SERPING1 causes hereditary angioedema R-HSA-9657689
Extracellular matrix organization R-HSA-1474244
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Disease R-HSA-1643685
Degradation of the extracellular matrix R-HSA-1474228
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Activation of Matrix Metalloproteinases R-HSA-1592389
Activation of Matrix Metalloproteinases R-HSA-1592389
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Defective factor XII causes hereditary angioedema R-HSA-9657688
Degradation of the extracellular matrix R-HSA-1474228
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Defective SERPING1 causes hereditary angioedema R-HSA-9657689
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Hemostasis R-HSA-109582
Diseases of hemostasis R-HSA-9671793
Disease R-HSA-1643685
Extracellular matrix organization R-HSA-1474244
Degradation of the extracellular matrix R-HSA-1474228
Extracellular matrix organization R-HSA-1474244
Defective SERPING1 causes hereditary angioedema R-HSA-9657689
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Defective factor XII causes hereditary angioedema R-HSA-9657688
Disease R-HSA-1643685
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Diseases of hemostasis R-HSA-9671793
Hemostasis R-HSA-109582
Activation of Matrix Metalloproteinases R-HSA-1592389
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Hemostasis R-HSA-109582
Activation of Matrix Metalloproteinases R-HSA-1592389
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Defective SERPING1 causes hereditary angioedema R-HSA-9657689
Disease R-HSA-1643685
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defective factor XII causes hereditary angioedema R-HSA-9657688
Diseases of hemostasis R-HSA-9671793
Degradation of the extracellular matrix R-HSA-1474228
Extracellular matrix organization R-HSA-1474244
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Hemostasis R-HSA-109582
Diseases of hemostasis R-HSA-9671793
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defective factor XII causes hereditary angioedema R-HSA-9657688
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Defective SERPING1 causes hereditary angioedema R-HSA-9657689
Disease R-HSA-1643685
Degradation of the extracellular matrix R-HSA-1474228
Degradation of the extracellular matrix R-HSA-1474228
Diseases of hemostasis R-HSA-9671793
Hemostasis R-HSA-109582
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Defective SERPING1 causes hereditary angioedema R-HSA-9657689
Disease R-HSA-1643685
Extracellular matrix organization R-HSA-1474244
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Activation of Matrix Metalloproteinases R-HSA-1592389
Defective factor XII causes hereditary angioedema R-HSA-9657688

Expression Atlas ENSG00000164344
LRG display in Ensembl gene LRG_565
NCBI gene (formerly Entrezgene) 3818
GeneCards 6371
HGNC Symbol HGNC:6371
MIM gene 229000
MIM morbid 612423
UniProtKB Gene Name E9PBC5
WikiGene 3818
Gene: F2
Ensembl ID : ENSG00000180210
Description: coagulation factor II, thrombin
Gene Synonyms:
9 APIs:
86 Possible Orthologues:

G alpha (q) signalling events R-HSA-416476
Post-translational protein modification R-HSA-597592
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Diseases of hemostasis R-HSA-9671793
GPCR downstream signalling R-HSA-388396
Defective factor XII causes hereditary angioedema R-HSA-9657688
Platelet Aggregation (Plug Formation) R-HSA-76009
Hemostasis R-HSA-109582
Common Pathway of Fibrin Clot Formation R-HSA-140875
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Peptide ligand-binding receptors R-HSA-375276
Defective F8 cleavage by thrombin R-HSA-9672391
Metabolism of proteins R-HSA-392499
Signaling by GPCR R-HSA-372790
Gamma-carboxylation of protein precursors R-HSA-159740
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Defective factor VIII causes hemophilia A R-HSA-9662001
Immune System R-HSA-168256
Regulation of Complement cascade R-HSA-977606
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Disease R-HSA-1643685
Cell surface interactions at the vascular wall R-HSA-202733
Innate Immune System R-HSA-168249
GPCR ligand binding R-HSA-500792
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Signal Transduction R-HSA-162582
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Complement cascade R-HSA-166658
Platelet activation, signaling and aggregation R-HSA-76002
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Platelet Aggregation (Plug Formation) R-HSA-76009
Defective F8 cleavage by thrombin R-HSA-9672391
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Cell surface interactions at the vascular wall R-HSA-202733
Complement cascade R-HSA-166658
Defective factor XII causes hereditary angioedema R-HSA-9657688
Defective factor VIII causes hemophilia A R-HSA-9662001
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Peptide ligand-binding receptors R-HSA-375276
Signal Transduction R-HSA-162582
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Hemostasis R-HSA-109582
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Immune System R-HSA-168256
Disease R-HSA-1643685
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Innate Immune System R-HSA-168249
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Post-translational protein modification R-HSA-597592
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Diseases of hemostasis R-HSA-9671793
Common Pathway of Fibrin Clot Formation R-HSA-140875
G alpha (q) signalling events R-HSA-416476
GPCR ligand binding R-HSA-500792
Regulation of Complement cascade R-HSA-977606
Gamma-carboxylation of protein precursors R-HSA-159740
Metabolism of proteins R-HSA-392499
Platelet activation, signaling and aggregation R-HSA-76002
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Diseases of hemostasis R-HSA-9671793
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Innate Immune System R-HSA-168249
Disease R-HSA-1643685
Platelet Aggregation (Plug Formation) R-HSA-76009
Gamma-carboxylation of protein precursors R-HSA-159740
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Complement cascade R-HSA-166658
Defective factor VIII causes hemophilia A R-HSA-9662001
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Cell surface interactions at the vascular wall R-HSA-202733
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Regulation of Complement cascade R-HSA-977606
Defective F8 cleavage by thrombin R-HSA-9672391
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Platelet activation, signaling and aggregation R-HSA-76002
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Common Pathway of Fibrin Clot Formation R-HSA-140875
Immune System R-HSA-168256
Defective factor XII causes hereditary angioedema R-HSA-9657688
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Hemostasis R-HSA-109582
G alpha (q) signalling events R-HSA-416476
Peptide ligand-binding receptors R-HSA-375276
GPCR ligand binding R-HSA-500792
Post-translational protein modification R-HSA-597592
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Signaling by GPCR R-HSA-372790
Complement cascade R-HSA-166658
Defective factor VIII causes hemophilia A R-HSA-9662001
Defective factor XII causes hereditary angioedema R-HSA-9657688
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Innate Immune System R-HSA-168249
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Hemostasis R-HSA-109582
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Regulation of Complement cascade R-HSA-977606
Platelet Aggregation (Plug Formation) R-HSA-76009
Platelet activation, signaling and aggregation R-HSA-76002
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Immune System R-HSA-168256
Gamma-carboxylation of protein precursors R-HSA-159740
G alpha (q) signalling events R-HSA-416476
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Post-translational protein modification R-HSA-597592
Common Pathway of Fibrin Clot Formation R-HSA-140875
Cell surface interactions at the vascular wall R-HSA-202733
Disease R-HSA-1643685
GPCR downstream signalling R-HSA-388396
Peptide ligand-binding receptors R-HSA-375276
Defective F8 cleavage by thrombin R-HSA-9672391
Diseases of hemostasis R-HSA-9671793
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Metabolism of proteins R-HSA-392499
Metabolism of proteins R-HSA-392499
Complement cascade R-HSA-166658
GPCR ligand binding R-HSA-500792
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Innate Immune System R-HSA-168249
Defective F8 cleavage by thrombin R-HSA-9672391
Platelet Aggregation (Plug Formation) R-HSA-76009
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Platelet activation, signaling and aggregation R-HSA-76002
G alpha (q) signalling events R-HSA-416476
Common Pathway of Fibrin Clot Formation R-HSA-140875
Regulation of Complement cascade R-HSA-977606
Defective factor VIII causes hemophilia A R-HSA-9662001
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Peptide ligand-binding receptors R-HSA-375276
GPCR downstream signalling R-HSA-388396
Post-translational protein modification R-HSA-597592
Hemostasis R-HSA-109582
Disease R-HSA-1643685
Immune System R-HSA-168256
Defective factor XII causes hereditary angioedema R-HSA-9657688
Signal Transduction R-HSA-162582
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Cell surface interactions at the vascular wall R-HSA-202733
Diseases of hemostasis R-HSA-9671793
Signaling by GPCR R-HSA-372790
Gamma-carboxylation of protein precursors R-HSA-159740
G alpha (q) signalling events R-HSA-416476
Peptide ligand-binding receptors R-HSA-375276
Defective factor VIII causes hemophilia A R-HSA-9662001
Diseases of hemostasis R-HSA-9671793
Defective F8 cleavage by thrombin R-HSA-9672391
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
GPCR downstream signalling R-HSA-388396
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Platelet Aggregation (Plug Formation) R-HSA-76009
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defective factor XII causes hereditary angioedema R-HSA-9657688
Signaling by GPCR R-HSA-372790
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Regulation of Complement cascade R-HSA-977606
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Cell surface interactions at the vascular wall R-HSA-202733
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Common Pathway of Fibrin Clot Formation R-HSA-140875
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
Disease R-HSA-1643685
Gamma-carboxylation of protein precursors R-HSA-159740
Complement cascade R-HSA-166658
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
GPCR ligand binding R-HSA-500792
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877

Expression Atlas ENSG00000180210
LRG display in Ensembl gene LRG_551
NCBI gene (formerly Entrezgene) 2147
GeneCards 3535
HGNC Symbol HGNC:3535
MIM gene 176930
MIM morbid 614390
UniProtKB Gene Name P00734
WikiGene 2147
Gene: C1S
Ensembl ID : ENSG00000182326
Description: complement C1s
Gene Synonyms:
2 APIs:
199 Possible Orthologues:

Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Complement cascade R-HSA-166658
Classical antibody-mediated complement activation R-HSA-173623
Initial triggering of complement R-HSA-166663
Creation of C4 and C2 activators R-HSA-166786
Regulation of Complement cascade R-HSA-977606
Initial triggering of complement R-HSA-166663
Classical antibody-mediated complement activation R-HSA-173623
Regulation of Complement cascade R-HSA-977606
Complement cascade R-HSA-166658
Creation of C4 and C2 activators R-HSA-166786
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Classical antibody-mediated complement activation R-HSA-173623
Initial triggering of complement R-HSA-166663
Regulation of Complement cascade R-HSA-977606
Innate Immune System R-HSA-168249
Creation of C4 and C2 activators R-HSA-166786
Immune System R-HSA-168256
Complement cascade R-HSA-166658
Classical antibody-mediated complement activation R-HSA-173623
Creation of C4 and C2 activators R-HSA-166786
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Regulation of Complement cascade R-HSA-977606
Initial triggering of complement R-HSA-166663
Complement cascade R-HSA-166658
Classical antibody-mediated complement activation R-HSA-173623
Creation of C4 and C2 activators R-HSA-166786
Regulation of Complement cascade R-HSA-977606
Complement cascade R-HSA-166658
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Initial triggering of complement R-HSA-166663
Creation of C4 and C2 activators R-HSA-166786
Initial triggering of complement R-HSA-166663
Classical antibody-mediated complement activation R-HSA-173623
Complement cascade R-HSA-166658
Regulation of Complement cascade R-HSA-977606
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Initial triggering of complement R-HSA-166663
Regulation of Complement cascade R-HSA-977606
Classical antibody-mediated complement activation R-HSA-173623
Complement cascade R-HSA-166658
Creation of C4 and C2 activators R-HSA-166786
Initial triggering of complement R-HSA-166663
Complement cascade R-HSA-166658
Immune System R-HSA-168256
Regulation of Complement cascade R-HSA-977606
Creation of C4 and C2 activators R-HSA-166786
Innate Immune System R-HSA-168249
Classical antibody-mediated complement activation R-HSA-173623
Regulation of Complement cascade R-HSA-977606
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Complement cascade R-HSA-166658
Classical antibody-mediated complement activation R-HSA-173623
Initial triggering of complement R-HSA-166663
Creation of C4 and C2 activators R-HSA-166786
Immune System R-HSA-168256
Initial triggering of complement R-HSA-166663
Regulation of Complement cascade R-HSA-977606
Innate Immune System R-HSA-168249
Complement cascade R-HSA-166658
Creation of C4 and C2 activators R-HSA-166786
Classical antibody-mediated complement activation R-HSA-173623

Expression Atlas ENSG00000182326
LRG display in Ensembl gene LRG_25
NCBI gene (formerly Entrezgene) 716
GeneCards 1247
HGNC Symbol HGNC:1247
MIM gene 120580
MIM morbid 617174
UniProtKB Gene Name P09871
WikiGene 716
Gene: F10
Ensembl ID : ENSG00000126218
Description: coagulation factor X
Gene Synonyms:
10 APIs:
239 Possible Orthologues:

Hemostasis R-HSA-109582
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Defective factor IX causes hemophilia B R-HSA-9668250
Defective factor IX causes thrombophilia R-HSA-9672383
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Defective F9 variant does not activate FX R-HSA-9673202
Common Pathway of Fibrin Clot Formation R-HSA-140875
Defective cofactor function of FVIIIa variant R-HSA-9672396
Metabolism of proteins R-HSA-392499
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Disease R-HSA-1643685
Post-translational protein modification R-HSA-597592
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Gamma-carboxylation of protein precursors R-HSA-159740
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defective factor VIII causes hemophilia A R-HSA-9662001
Diseases of hemostasis R-HSA-9671793
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Disease R-HSA-1643685
Defective factor IX causes hemophilia B R-HSA-9668250
Defective factor IX causes thrombophilia R-HSA-9672383
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Defective factor VIII causes hemophilia A R-HSA-9662001
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Defective cofactor function of FVIIIa variant R-HSA-9672396
Gamma-carboxylation of protein precursors R-HSA-159740
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
Defective F9 variant does not activate FX R-HSA-9673202
Common Pathway of Fibrin Clot Formation R-HSA-140875
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Diseases of hemostasis R-HSA-9671793
Hemostasis R-HSA-109582
Hemostasis R-HSA-109582
Defective F9 variant does not activate FX R-HSA-9673202
Defective factor VIII causes hemophilia A R-HSA-9662001
Disease R-HSA-1643685
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Common Pathway of Fibrin Clot Formation R-HSA-140875
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Defective factor IX causes hemophilia B R-HSA-9668250
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defective factor IX causes thrombophilia R-HSA-9672383
Diseases of hemostasis R-HSA-9671793
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Post-translational protein modification R-HSA-597592
Gamma-carboxylation of protein precursors R-HSA-159740
Metabolism of proteins R-HSA-392499
Defective cofactor function of FVIIIa variant R-HSA-9672396
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
Defective factor IX causes thrombophilia R-HSA-9672383
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Common Pathway of Fibrin Clot Formation R-HSA-140875
Hemostasis R-HSA-109582
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defective factor VIII causes hemophilia A R-HSA-9662001
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Defective cofactor function of FVIIIa variant R-HSA-9672396
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Gamma-carboxylation of protein precursors R-HSA-159740
Disease R-HSA-1643685
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Diseases of hemostasis R-HSA-9671793
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Defective F9 variant does not activate FX R-HSA-9673202
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Defective factor IX causes hemophilia B R-HSA-9668250
Hemostasis R-HSA-109582
Diseases of hemostasis R-HSA-9671793
Defective factor IX causes thrombophilia R-HSA-9672383
Defective cofactor function of FVIIIa variant R-HSA-9672396
Gamma-carboxylation of protein precursors R-HSA-159740
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Common Pathway of Fibrin Clot Formation R-HSA-140875
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Post-translational protein modification R-HSA-597592
Defective factor IX causes hemophilia B R-HSA-9668250
Disease R-HSA-1643685
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Defective F9 variant does not activate FX R-HSA-9673202
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Defective factor VIII causes hemophilia A R-HSA-9662001
Metabolism of proteins R-HSA-392499
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Post-translational protein modification R-HSA-597592
Disease R-HSA-1643685
Defective factor IX causes hemophilia B R-HSA-9668250
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Defective F9 variant does not activate FX R-HSA-9673202
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Gamma-carboxylation of protein precursors R-HSA-159740
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Defective cofactor function of FVIIIa variant R-HSA-9672396
Defective factor VIII causes hemophilia A R-HSA-9662001
Defective factor IX causes thrombophilia R-HSA-9672383
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Common Pathway of Fibrin Clot Formation R-HSA-140875
Diseases of hemostasis R-HSA-9671793
Metabolism of proteins R-HSA-392499
Hemostasis R-HSA-109582
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Gamma-carboxylation of protein precursors R-HSA-159740
Common Pathway of Fibrin Clot Formation R-HSA-140875
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defective cofactor function of FVIIIa variant R-HSA-9672396
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Defective factor IX causes thrombophilia R-HSA-9672383
Defective F9 variant does not activate FX R-HSA-9673202
Metabolism of proteins R-HSA-392499
Diseases of hemostasis R-HSA-9671793
Hemostasis R-HSA-109582
Disease R-HSA-1643685
Defective factor IX causes hemophilia B R-HSA-9668250
Defective factor VIII causes hemophilia A R-HSA-9662001
Post-translational protein modification R-HSA-597592
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Gamma-carboxylation of protein precursors R-HSA-159740
Hemostasis R-HSA-109582
Defective factor IX causes thrombophilia R-HSA-9672383
Defective factor IX causes hemophilia B R-HSA-9668250
Defective factor VIII causes hemophilia A R-HSA-9662001
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Disease R-HSA-1643685
Post-translational protein modification R-HSA-597592
Common Pathway of Fibrin Clot Formation R-HSA-140875
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Defective cofactor function of FVIIIa variant R-HSA-9672396
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Diseases of hemostasis R-HSA-9671793
Metabolism of proteins R-HSA-392499
Defective F9 variant does not activate FX R-HSA-9673202
Diseases of hemostasis R-HSA-9671793
Defective factor IX causes hemophilia B R-HSA-9668250
Defective factor VIII causes hemophilia A R-HSA-9662001
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159763
Removal of aminoterminal propeptides from gamma-carboxylated proteins R-HSA-159782
Hemostasis R-HSA-109582
Post-translational protein modification R-HSA-597592
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins R-HSA-159854
Common Pathway of Fibrin Clot Formation R-HSA-140875
Gamma-carboxylation of protein precursors R-HSA-159740
Metabolism of proteins R-HSA-392499
Gamma carboxylation, hypusine formation and arylsulfatase activation R-HSA-163841
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Defective factor IX causes thrombophilia R-HSA-9672383
Disease R-HSA-1643685
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834
Defective F9 variant does not activate FX R-HSA-9673202
Defective cofactor function of FVIIIa variant R-HSA-9672396

Expression Atlas ENSG00000126218
LRG display in Ensembl gene LRG_548
NCBI gene (formerly Entrezgene) 2159
GeneCards 3528
HGNC Symbol HGNC:3528
MIM gene 613872
MIM morbid 227600
UniProtKB Gene Name Q5JVE8
WikiGene 2159
Gene: EPHX2
Ensembl ID : ENSG00000120915
Description: epoxide hydrolase 2
Gene Synonyms: ABHD20,SEH
2 APIs:
204 Possible Orthologues:

Metabolism R-HSA-1430728
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) R-HSA-2142670
Biosynthesis of maresins R-HSA-9018682
Arachidonic acid metabolism R-HSA-2142753
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Fatty acid metabolism R-HSA-8978868
Metabolism of lipids R-HSA-556833
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Protein localization R-HSA-9609507
Peroxisomal protein import R-HSA-9033241
Peroxisomal protein import R-HSA-9033241
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) R-HSA-2142670
Metabolism of lipids R-HSA-556833
Arachidonic acid metabolism R-HSA-2142753
Fatty acid metabolism R-HSA-8978868
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Biosynthesis of maresins R-HSA-9018682
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Metabolism R-HSA-1430728
Protein localization R-HSA-9609507
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Biosynthesis of maresins R-HSA-9018682
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Protein localization R-HSA-9609507
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) R-HSA-2142670
Metabolism R-HSA-1430728
Fatty acid metabolism R-HSA-8978868
Metabolism of lipids R-HSA-556833
Peroxisomal protein import R-HSA-9033241
Arachidonic acid metabolism R-HSA-2142753
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Metabolism R-HSA-1430728
Biosynthesis of maresins R-HSA-9018682
Peroxisomal protein import R-HSA-9033241
Protein localization R-HSA-9609507
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Fatty acid metabolism R-HSA-8978868
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) R-HSA-2142670
Arachidonic acid metabolism R-HSA-2142753
Metabolism of lipids R-HSA-556833
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) R-HSA-2142670
Protein localization R-HSA-9609507
Arachidonic acid metabolism R-HSA-2142753
Peroxisomal protein import R-HSA-9033241
Metabolism R-HSA-1430728
Biosynthesis of maresins R-HSA-9018682
Fatty acid metabolism R-HSA-8978868
Metabolism of lipids R-HSA-556833
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Peroxisomal protein import R-HSA-9033241
Metabolism of lipids R-HSA-556833
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Biosynthesis of maresins R-HSA-9018682
Metabolism R-HSA-1430728
Fatty acid metabolism R-HSA-8978868
Arachidonic acid metabolism R-HSA-2142753
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) R-HSA-2142670
Protein localization R-HSA-9609507
Peroxisomal protein import R-HSA-9033241
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Metabolism of lipids R-HSA-556833
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) R-HSA-2142670
Metabolism R-HSA-1430728
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Arachidonic acid metabolism R-HSA-2142753
Fatty acid metabolism R-HSA-8978868
Biosynthesis of maresins R-HSA-9018682
Protein localization R-HSA-9609507
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Metabolism of lipids R-HSA-556833
Arachidonic acid metabolism R-HSA-2142753
Biosynthesis of maresins R-HSA-9018682
Fatty acid metabolism R-HSA-8978868
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Metabolism R-HSA-1430728
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) R-HSA-2142670
Peroxisomal protein import R-HSA-9033241
Protein localization R-HSA-9609507
Peroxisomal protein import R-HSA-9033241
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Protein localization R-HSA-9609507
Biosynthesis of maresins R-HSA-9018682
Arachidonic acid metabolism R-HSA-2142753
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) R-HSA-2142670
Fatty acid metabolism R-HSA-8978868
Arachidonic acid metabolism R-HSA-2142753
Fatty acid metabolism R-HSA-8978868
Metabolism of lipids R-HSA-556833
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) R-HSA-2142670
Metabolism R-HSA-1430728
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678
Biosynthesis of maresins R-HSA-9018682
Biosynthesis of DHA-derived SPMs R-HSA-9018677
Protein localization R-HSA-9609507
Peroxisomal protein import R-HSA-9033241

Expression Atlas ENSG00000120915
NCBI gene (formerly Entrezgene) 2053
GeneCards 3402
HGNC Symbol HGNC:3402
MIM gene 132811
MIM morbid 143890
UniProtKB Gene Name P34913
WikiGene 2053