Gene: RXRG
Ensembl ID : ENSG00000143171
Description: retinoid X receptor gamma
Gene Synonyms: NR2B3,RXR-GAMMA,RXRGAMMA
2 APIs:
277 Possible Orthologues:

Gene expression (Transcription) R-HSA-74160
Signaling by Nuclear Receptors R-HSA-9006931
RNA Polymerase II Transcription R-HSA-73857
Signaling by Retinoic Acid R-HSA-5362517
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Nuclear Receptor transcription pathway R-HSA-383280
Signaling by Retinoic Acid R-HSA-5362517
Generic Transcription Pathway R-HSA-212436
Nuclear Receptor transcription pathway R-HSA-383280
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
Signaling by Nuclear Receptors R-HSA-9006931
Signal Transduction R-HSA-162582
Nuclear Receptor transcription pathway R-HSA-383280
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Signaling by Retinoic Acid R-HSA-5362517
Signaling by Nuclear Receptors R-HSA-9006931
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Nuclear Receptor transcription pathway R-HSA-383280
Signaling by Retinoic Acid R-HSA-5362517
Signaling by Nuclear Receptors R-HSA-9006931
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Nuclear Receptor transcription pathway R-HSA-383280
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Retinoic Acid R-HSA-5362517
RNA Polymerase II Transcription R-HSA-73857
Nuclear Receptor transcription pathway R-HSA-383280
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Retinoic Acid R-HSA-5362517
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Nuclear Receptor transcription pathway R-HSA-383280
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Signaling by Retinoic Acid R-HSA-5362517
Signaling by Nuclear Receptors R-HSA-9006931
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Signaling by Retinoic Acid R-HSA-5362517
Nuclear Receptor transcription pathway R-HSA-383280
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
Signaling by Nuclear Receptors R-HSA-9006931
RNA Polymerase II Transcription R-HSA-73857
Signaling by Retinoic Acid R-HSA-5362517
Gene expression (Transcription) R-HSA-74160
Signaling by Nuclear Receptors R-HSA-9006931
Generic Transcription Pathway R-HSA-212436
Nuclear Receptor transcription pathway R-HSA-383280
Signal Transduction R-HSA-162582
RNA Polymerase II Transcription R-HSA-73857

Expression Atlas ENSG00000143171
NCBI gene (formerly Entrezgene) 6258
GeneCards 10479
HGNC Symbol HGNC:10479
MIM gene 180247
UniProtKB Gene Name P48443
WikiGene 6258
Gene: RXRB
Ensembl ID : ENSG00000204231
Description: retinoid X receptor beta
Gene Synonyms: H-2RIIBP,NR2B2,RCOR-1,RXR-BETA,RXRBETA
2 APIs:
215 Possible Orthologues:

NR1H2 and NR1H3-mediated signaling R-HSA-9024446
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake R-HSA-9031525
RNA Polymerase II Transcription R-HSA-73857
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433
Signaling by Retinoic Acid R-HSA-5362517
Signal Transduction R-HSA-162582
NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis R-HSA-9632974
Signaling by Nuclear Receptors R-HSA-9006931
Nuclear Receptor transcription pathway R-HSA-383280
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558
Metabolism R-HSA-1430728
NR1H2 and NR1H3-mediated signaling R-HSA-9024446
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569
PPARA activates gene expression R-HSA-1989781
Regulation of lipid metabolism by PPARalpha R-HSA-400206
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose R-HSA-9031528
Metabolism of lipids R-HSA-556833
Nuclear Receptor transcription pathway R-HSA-383280
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569
Signaling by Retinoic Acid R-HSA-5362517
Generic Transcription Pathway R-HSA-212436
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Signaling by Nuclear Receptors R-HSA-9006931
NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis R-HSA-9632974
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433
NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake R-HSA-9031525
Gene expression (Transcription) R-HSA-74160
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose R-HSA-9031528
NR1H2 and NR1H3-mediated signaling R-HSA-9024446
Signal Transduction R-HSA-162582
Regulation of lipid metabolism by PPARalpha R-HSA-400206
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558
PPARA activates gene expression R-HSA-1989781
RNA Polymerase II Transcription R-HSA-73857
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Generic Transcription Pathway R-HSA-212436
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose R-HSA-9031528
Gene expression (Transcription) R-HSA-74160
Metabolism R-HSA-1430728
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569
NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake R-HSA-9031525
NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis R-HSA-9632974
Signaling by Nuclear Receptors R-HSA-9006931
Metabolism of lipids R-HSA-556833
PPARA activates gene expression R-HSA-1989781
NR1H2 and NR1H3-mediated signaling R-HSA-9024446
Nuclear Receptor transcription pathway R-HSA-383280
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433
Signaling by Retinoic Acid R-HSA-5362517
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558
Regulation of lipid metabolism by PPARalpha R-HSA-400206
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569
NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis R-HSA-9632974
PPARA activates gene expression R-HSA-1989781
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
NR1H2 and NR1H3-mediated signaling R-HSA-9024446
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558
NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake R-HSA-9031525
Signaling by Retinoic Acid R-HSA-5362517
RNA Polymerase II Transcription R-HSA-73857
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose R-HSA-9031528
Nuclear Receptor transcription pathway R-HSA-383280
Signaling by Nuclear Receptors R-HSA-9006931
Signal Transduction R-HSA-162582
Regulation of lipid metabolism by PPARalpha R-HSA-400206
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558
Signal Transduction R-HSA-162582
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
PPARA activates gene expression R-HSA-1989781
Signaling by Retinoic Acid R-HSA-5362517
Signaling by Nuclear Receptors R-HSA-9006931
NR1H2 and NR1H3-mediated signaling R-HSA-9024446
Generic Transcription Pathway R-HSA-212436
Nuclear Receptor transcription pathway R-HSA-383280
NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis R-HSA-9632974
RNA Polymerase II Transcription R-HSA-73857
NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake R-HSA-9031525
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose R-HSA-9031528
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569
Gene expression (Transcription) R-HSA-74160
NR1H2 and NR1H3-mediated signaling R-HSA-9024446
Metabolism of lipids R-HSA-556833
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569
Regulation of lipid metabolism by PPARalpha R-HSA-400206
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433
NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake R-HSA-9031525
NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis R-HSA-9632974
PPARA activates gene expression R-HSA-1989781
Nuclear Receptor transcription pathway R-HSA-383280
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
Metabolism R-HSA-1430728
Signaling by Retinoic Acid R-HSA-5362517
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Signaling by Nuclear Receptors R-HSA-9006931
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose R-HSA-9031528
Gene expression (Transcription) R-HSA-74160
PPARA activates gene expression R-HSA-1989781
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433
Nuclear Receptor transcription pathway R-HSA-383280
NR1H2 and NR1H3-mediated signaling R-HSA-9024446
NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake R-HSA-9031525
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558
Generic Transcription Pathway R-HSA-212436
Regulation of lipid metabolism by PPARalpha R-HSA-400206
RNA Polymerase II Transcription R-HSA-73857
Metabolism of lipids R-HSA-556833
Signaling by Nuclear Receptors R-HSA-9006931
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569
Signal Transduction R-HSA-162582
Metabolism R-HSA-1430728
Signaling by Retinoic Acid R-HSA-5362517
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose R-HSA-9031528
NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis R-HSA-9632974
Signaling by Nuclear Receptors R-HSA-9006931
Nuclear Receptor transcription pathway R-HSA-383280
Signal Transduction R-HSA-162582
RNA Polymerase II Transcription R-HSA-73857
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558
Gene expression (Transcription) R-HSA-74160
PPARA activates gene expression R-HSA-1989781
Signaling by Retinoic Acid R-HSA-5362517
Regulation of lipid metabolism by PPARalpha R-HSA-400206
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569
Metabolism R-HSA-1430728
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433
Metabolism of lipids R-HSA-556833
NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis R-HSA-9632974
NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake R-HSA-9031525
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose R-HSA-9031528
Generic Transcription Pathway R-HSA-212436
Metabolism of lipids R-HSA-556833
Signaling by Nuclear Receptors R-HSA-9006931
Gene expression (Transcription) R-HSA-74160
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558
Metabolism R-HSA-1430728
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433
PPARA activates gene expression R-HSA-1989781
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569
Signaling by Retinoic Acid R-HSA-5362517
Generic Transcription Pathway R-HSA-212436
NR1H2 and NR1H3-mediated signaling R-HSA-9024446
Nuclear Receptor transcription pathway R-HSA-383280
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Signal Transduction R-HSA-162582
NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis R-HSA-9632974
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose R-HSA-9031528
RNA Polymerase II Transcription R-HSA-73857
NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake R-HSA-9031525
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433
Gene expression (Transcription) R-HSA-74160
Signaling by Nuclear Receptors R-HSA-9006931
Signal Transduction R-HSA-162582
Signaling by Retinoic Acid R-HSA-5362517
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Generic Transcription Pathway R-HSA-212436
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose R-HSA-9031528
RNA Polymerase II Transcription R-HSA-73857
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558
Metabolism of lipids R-HSA-556833
PPARA activates gene expression R-HSA-1989781
Nuclear Receptor transcription pathway R-HSA-383280
Metabolism R-HSA-1430728
NR1H2 and NR1H3-mediated signaling R-HSA-9024446
NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake R-HSA-9031525
NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis R-HSA-9632974

Expression Atlas ENSG00000204231
NCBI gene (formerly Entrezgene) 6257
GeneCards 10478
HGNC Symbol HGNC:10478
MIM gene 180246
UniProtKB Gene Name Q5STP9
WikiGene 6257
Gene: ESR2
Ensembl ID : ENSG00000140009
Description: estrogen receptor 2
Gene Synonyms: ER-BETA,ERB,NR3A2
32 APIs:
274 Possible Orthologues:

Signaling by Nuclear Receptors R-HSA-9006931
Nuclear Receptor transcription pathway R-HSA-383280
Extra-nuclear estrogen signaling R-HSA-9009391
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
PIP3 activates AKT signaling R-HSA-1257604
ESR-mediated signaling R-HSA-8939211
Negative regulation of the PI3K/AKT network R-HSA-199418
Disease R-HSA-1643685
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Generic Transcription Pathway R-HSA-212436
PIP3 activates AKT signaling R-HSA-1257604
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RNA Polymerase II Transcription R-HSA-73857
ESR-mediated signaling R-HSA-8939211
Extra-nuclear estrogen signaling R-HSA-9009391
Gene expression (Transcription) R-HSA-74160
Negative regulation of the PI3K/AKT network R-HSA-199418
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
Signaling by Nuclear Receptors R-HSA-9006931
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Disease R-HSA-1643685
Nuclear Receptor transcription pathway R-HSA-383280
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI3K/AKT Signaling in Cancer R-HSA-2219528
ESR-mediated signaling R-HSA-8939211
Nuclear Receptor transcription pathway R-HSA-383280
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Generic Transcription Pathway R-HSA-212436
Extra-nuclear estrogen signaling R-HSA-9009391
Negative regulation of the PI3K/AKT network R-HSA-199418
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Signaling by Nuclear Receptors R-HSA-9006931
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Gene expression (Transcription) R-HSA-74160
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Nuclear Receptor transcription pathway R-HSA-383280
ESR-mediated signaling R-HSA-8939211
RNA Polymerase II Transcription R-HSA-73857
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Negative regulation of the PI3K/AKT network R-HSA-199418
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Extra-nuclear estrogen signaling R-HSA-9009391
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
Signaling by Nuclear Receptors R-HSA-9006931
Generic Transcription Pathway R-HSA-212436
ESR-mediated signaling R-HSA-8939211
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Gene expression (Transcription) R-HSA-74160
Negative regulation of the PI3K/AKT network R-HSA-199418
RNA Polymerase II Transcription R-HSA-73857
Intracellular signaling by second messengers R-HSA-9006925
Nuclear Receptor transcription pathway R-HSA-383280
Signaling by Nuclear Receptors R-HSA-9006931
PI3K/AKT Signaling in Cancer R-HSA-2219528
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Extra-nuclear estrogen signaling R-HSA-9009391
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Nuclear Receptors R-HSA-9006931
Gene expression (Transcription) R-HSA-74160
Negative regulation of the PI3K/AKT network R-HSA-199418
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
ESR-mediated signaling R-HSA-8939211
PI3K/AKT Signaling in Cancer R-HSA-2219528
Nuclear Receptor transcription pathway R-HSA-383280
Intracellular signaling by second messengers R-HSA-9006925
Generic Transcription Pathway R-HSA-212436
Extra-nuclear estrogen signaling R-HSA-9009391
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RNA Polymerase II Transcription R-HSA-73857
Negative regulation of the PI3K/AKT network R-HSA-199418
Generic Transcription Pathway R-HSA-212436
Nuclear Receptor transcription pathway R-HSA-383280
PIP3 activates AKT signaling R-HSA-1257604
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Extra-nuclear estrogen signaling R-HSA-9009391
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Disease R-HSA-1643685
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
ESR-mediated signaling R-HSA-8939211
Signaling by Nuclear Receptors R-HSA-9006931
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Nuclear Receptors R-HSA-9006931
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear Receptor transcription pathway R-HSA-383280
Disease R-HSA-1643685
Negative regulation of the PI3K/AKT network R-HSA-199418
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Intracellular signaling by second messengers R-HSA-9006925
ESR-mediated signaling R-HSA-8939211
Generic Transcription Pathway R-HSA-212436
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Extra-nuclear estrogen signaling R-HSA-9009391
Intracellular signaling by second messengers R-HSA-9006925
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Extra-nuclear estrogen signaling R-HSA-9009391
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
Signaling by Nuclear Receptors R-HSA-9006931
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI3K/AKT Signaling in Cancer R-HSA-2219528
RNA Polymerase II Transcription R-HSA-73857
Nuclear Receptor transcription pathway R-HSA-383280
Gene expression (Transcription) R-HSA-74160
Negative regulation of the PI3K/AKT network R-HSA-199418
ESR-mediated signaling R-HSA-8939211
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Extra-nuclear estrogen signaling R-HSA-9009391
Negative regulation of the PI3K/AKT network R-HSA-199418
Nuclear Receptor transcription pathway R-HSA-383280
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Nuclear Receptors R-HSA-9006931
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Gene expression (Transcription) R-HSA-74160
PI3K/AKT Signaling in Cancer R-HSA-2219528
RNA Polymerase II Transcription R-HSA-73857
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
ESR-mediated signaling R-HSA-8939211

Expression Atlas ENSG00000140009
NCBI gene (formerly Entrezgene) 2100
GeneCards 3468
HGNC Symbol HGNC:3468
MIM gene 601663
MIM morbid 618187
UniProtKB Gene Name Q92731
WikiGene 2100
Gene: ESR1
Ensembl ID : ENSG00000091831
Description: estrogen receptor 1
Gene Synonyms: ER-ALPHA,ERA,ESR,NR3A1
45 APIs:
212 Possible Orthologues:

PI3K/AKT Signaling in Cancer R-HSA-2219528
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Transcriptional regulation by RUNX2 R-HSA-8878166
Disease R-HSA-1643685
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Estrogen-dependent gene expression R-HSA-9018519
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nuclear Receptor transcription pathway R-HSA-383280
Deubiquitination R-HSA-5688426
Negative regulation of the PI3K/AKT network R-HSA-199418
Signal Transduction R-HSA-162582
Signaling by ERBB4 R-HSA-1236394
Gene expression (Transcription) R-HSA-74160
ESR-mediated signaling R-HSA-8939211
Extra-nuclear estrogen signaling R-HSA-9009391
Metabolism of proteins R-HSA-392499
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
SUMOylation of intracellular receptors R-HSA-4090294
RNA Polymerase II Transcription R-HSA-73857
Ovarian tumor domain proteases R-HSA-5689896
Post-translational protein modification R-HSA-597592
Generic Transcription Pathway R-HSA-212436
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX1 R-HSA-8878171
SUMOylation R-HSA-2990846
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by Nuclear Receptors R-HSA-9006931
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Nuclear Receptor transcription pathway R-HSA-383280
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Metabolism of proteins R-HSA-392499
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by ERBB4 R-HSA-1236394
SUMOylation of intracellular receptors R-HSA-4090294
Disease R-HSA-1643685
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Extra-nuclear estrogen signaling R-HSA-9009391
Deubiquitination R-HSA-5688426
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
SUMOylation R-HSA-2990846
Negative regulation of the PI3K/AKT network R-HSA-199418
Nuclear signaling by ERBB4 R-HSA-1251985
ESR-mediated signaling R-HSA-8939211
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Generic Transcription Pathway R-HSA-212436
Signaling by Nuclear Receptors R-HSA-9006931
PI3K/AKT Signaling in Cancer R-HSA-2219528
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX2 R-HSA-8878166
RNA Polymerase II Transcription R-HSA-73857
Post-translational protein modification R-HSA-597592
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256
Ovarian tumor domain proteases R-HSA-5689896
Transcriptional regulation by RUNX1 R-HSA-8878171
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987
Estrogen-dependent gene expression R-HSA-9018519
PIP3 activates AKT signaling R-HSA-1257604
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Regulation of RUNX2 expression and activity R-HSA-8939902
Deubiquitination R-HSA-5688426
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Nuclear Receptors R-HSA-9006931
ESR-mediated signaling R-HSA-8939211
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987
Transcriptional regulation by RUNX2 R-HSA-8878166
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
SUMOylation R-HSA-2990846
SUMOylation of intracellular receptors R-HSA-4090294
Extra-nuclear estrogen signaling R-HSA-9009391
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI3K/AKT Signaling in Cancer R-HSA-2219528
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Nuclear signaling by ERBB4 R-HSA-1251985
Negative regulation of the PI3K/AKT network R-HSA-199418
Nuclear Receptor transcription pathway R-HSA-383280
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Intracellular signaling by second messengers R-HSA-9006925
Post-translational protein modification R-HSA-597592
Signal Transduction R-HSA-162582
Estrogen-dependent gene expression R-HSA-9018519
Ovarian tumor domain proteases R-HSA-5689896
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256
Signaling by ERBB4 R-HSA-1236394
Metabolism of proteins R-HSA-392499
Estrogen-dependent gene expression R-HSA-9018519
Deubiquitination R-HSA-5688426
Generic Transcription Pathway R-HSA-212436
Post-translational protein modification R-HSA-597592
Extra-nuclear estrogen signaling R-HSA-9009391
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI3K/AKT Signaling in Cancer R-HSA-2219528
Transcriptional regulation by RUNX1 R-HSA-8878171
ESR-mediated signaling R-HSA-8939211
Intracellular signaling by second messengers R-HSA-9006925
Nuclear signaling by ERBB4 R-HSA-1251985
Transcriptional regulation by RUNX2 R-HSA-8878166
Gene expression (Transcription) R-HSA-74160
Nuclear Receptor transcription pathway R-HSA-383280
Signaling by ERBB4 R-HSA-1236394
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
SUMOylation R-HSA-2990846
SUMOylation of intracellular receptors R-HSA-4090294
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Metabolism of proteins R-HSA-392499
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256
RNA Polymerase II Transcription R-HSA-73857
Ovarian tumor domain proteases R-HSA-5689896
Negative regulation of the PI3K/AKT network R-HSA-199418
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by Nuclear Receptors R-HSA-9006931
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Metabolism of proteins R-HSA-392499
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Gene expression (Transcription) R-HSA-74160
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256
Estrogen-dependent gene expression R-HSA-9018519
RNA Polymerase II Transcription R-HSA-73857
Signaling by ERBB4 R-HSA-1236394
Signaling by Nuclear Receptors R-HSA-9006931
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Regulation of RUNX2 expression and activity R-HSA-8939902
Generic Transcription Pathway R-HSA-212436
ESR-mediated signaling R-HSA-8939211
Transcriptional regulation by RUNX2 R-HSA-8878166
Transcriptional regulation by RUNX1 R-HSA-8878171
SUMOylation R-HSA-2990846
Negative regulation of the PI3K/AKT network R-HSA-199418
Nuclear signaling by ERBB4 R-HSA-1251985
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
SUMOylation of intracellular receptors R-HSA-4090294
Extra-nuclear estrogen signaling R-HSA-9009391
Intracellular signaling by second messengers R-HSA-9006925
Nuclear Receptor transcription pathway R-HSA-383280
Post-translational protein modification R-HSA-597592
PI3K/AKT Signaling in Cancer R-HSA-2219528
Deubiquitination R-HSA-5688426
Signal Transduction R-HSA-162582
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Ovarian tumor domain proteases R-HSA-5689896
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PIP3 activates AKT signaling R-HSA-1257604
Extra-nuclear estrogen signaling R-HSA-9009391
Ovarian tumor domain proteases R-HSA-5689896
Nuclear Receptor transcription pathway R-HSA-383280
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by Nuclear Receptors R-HSA-9006931
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256
Estrogen-dependent gene expression R-HSA-9018519
Metabolism of proteins R-HSA-392499
Deubiquitination R-HSA-5688426
RNA Polymerase II Transcription R-HSA-73857
Signaling by ERBB4 R-HSA-1236394
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI3K/AKT Signaling in Cancer R-HSA-2219528
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Negative regulation of the PI3K/AKT network R-HSA-199418
Nuclear signaling by ERBB4 R-HSA-1251985
SUMOylation R-HSA-2990846
SUMOylation of intracellular receptors R-HSA-4090294
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Gene expression (Transcription) R-HSA-74160
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Transcriptional regulation by RUNX1 R-HSA-8878171
Disease R-HSA-1643685
Regulation of RUNX2 expression and activity R-HSA-8939902
ESR-mediated signaling R-HSA-8939211
Post-translational protein modification R-HSA-597592
Generic Transcription Pathway R-HSA-212436
Negative regulation of the PI3K/AKT network R-HSA-199418
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
ESR-mediated signaling R-HSA-8939211
SUMOylation R-HSA-2990846
Metabolism of proteins R-HSA-392499
Nuclear signaling by ERBB4 R-HSA-1251985
Post-translational protein modification R-HSA-597592
Signal Transduction R-HSA-162582
Signaling by Nuclear Receptors R-HSA-9006931
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256
Generic Transcription Pathway R-HSA-212436
Regulation of RUNX2 expression and activity R-HSA-8939902
Disease R-HSA-1643685
Intracellular signaling by second messengers R-HSA-9006925
RNA Polymerase II Transcription R-HSA-73857
SUMOylation of intracellular receptors R-HSA-4090294
Extra-nuclear estrogen signaling R-HSA-9009391
Ovarian tumor domain proteases R-HSA-5689896
Signaling by ERBB4 R-HSA-1236394
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Deubiquitination R-HSA-5688426
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Estrogen-dependent gene expression R-HSA-9018519
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI3K/AKT Signaling in Cancer R-HSA-2219528
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX2 R-HSA-8878166
Nuclear Receptor transcription pathway R-HSA-383280
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Generic Transcription Pathway R-HSA-212436
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Transcriptional regulation by RUNX1 R-HSA-8878171
Metabolism of proteins R-HSA-392499
Deubiquitination R-HSA-5688426
Estrogen-dependent gene expression R-HSA-9018519
Regulation of RUNX2 expression and activity R-HSA-8939902
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987
Disease R-HSA-1643685
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
SUMOylation of intracellular receptors R-HSA-4090294
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256
Nuclear Receptor transcription pathway R-HSA-383280
RNA Polymerase II Transcription R-HSA-73857
Signaling by Nuclear Receptors R-HSA-9006931
ESR-mediated signaling R-HSA-8939211
Nuclear signaling by ERBB4 R-HSA-1251985
SUMOylation R-HSA-2990846
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of the PI3K/AKT network R-HSA-199418
Ovarian tumor domain proteases R-HSA-5689896
Post-translational protein modification R-HSA-597592
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Extra-nuclear estrogen signaling R-HSA-9009391
Gene expression (Transcription) R-HSA-74160
Signaling by ERBB4 R-HSA-1236394
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Nuclear Receptors R-HSA-9006931
SUMOylation of intracellular receptors R-HSA-4090294
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Signal Transduction R-HSA-162582
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256
Estrogen-dependent gene expression R-HSA-9018519
ESR-mediated signaling R-HSA-8939211
PI3K/AKT Signaling in Cancer R-HSA-2219528
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
SUMOylation R-HSA-2990846
Generic Transcription Pathway R-HSA-212436
Nuclear signaling by ERBB4 R-HSA-1251985
Post-translational protein modification R-HSA-597592
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by ERBB4 R-HSA-1236394
Extra-nuclear estrogen signaling R-HSA-9009391
Nuclear Receptor transcription pathway R-HSA-383280
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional regulation by RUNX1 R-HSA-8878171
Deubiquitination R-HSA-5688426
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Transcriptional regulation by RUNX2 R-HSA-8878166
Ovarian tumor domain proteases R-HSA-5689896
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Metabolism of proteins R-HSA-392499
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987
Negative regulation of the PI3K/AKT network R-HSA-199418
Disease R-HSA-1643685
Post-translational protein modification R-HSA-597592
SUMOylation of intracellular receptors R-HSA-4090294
Nuclear Receptor transcription pathway R-HSA-383280
PI3K/AKT Signaling in Cancer R-HSA-2219528
RNA Polymerase II Transcription R-HSA-73857
Estrogen-dependent gene expression R-HSA-9018519
Intracellular signaling by second messengers R-HSA-9006925
SUMOylation R-HSA-2990846
Deubiquitination R-HSA-5688426
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signal Transduction R-HSA-162582
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987
Metabolism of proteins R-HSA-392499
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Nuclear Receptors R-HSA-9006931
Nuclear signaling by ERBB4 R-HSA-1251985
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256
PIP3 activates AKT signaling R-HSA-1257604
Gene expression (Transcription) R-HSA-74160
ESR-mediated signaling R-HSA-8939211
Regulation of RUNX2 expression and activity R-HSA-8939902
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by ERBB4 R-HSA-1236394
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Transcriptional regulation by RUNX1 R-HSA-8878171
Ovarian tumor domain proteases R-HSA-5689896

Expression Atlas ENSG00000091831
LRG display in Ensembl gene LRG_992
NCBI gene (formerly Entrezgene) 2099
GeneCards 3467
HGNC Symbol HGNC:3467
MIM gene 133430
MIM morbid 615363
UniProtKB Gene Name Q9UE35
WikiGene 2099
Gene: ESR2
Ensembl ID : ENSG00000140009
Description: estrogen receptor 2
Gene Synonyms: ER-BETA,ERB,NR3A2
32 APIs:
274 Possible Orthologues:

Signaling by Nuclear Receptors R-HSA-9006931
Nuclear Receptor transcription pathway R-HSA-383280
Extra-nuclear estrogen signaling R-HSA-9009391
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
PIP3 activates AKT signaling R-HSA-1257604
ESR-mediated signaling R-HSA-8939211
Negative regulation of the PI3K/AKT network R-HSA-199418
Disease R-HSA-1643685
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Generic Transcription Pathway R-HSA-212436
PIP3 activates AKT signaling R-HSA-1257604
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RNA Polymerase II Transcription R-HSA-73857
ESR-mediated signaling R-HSA-8939211
Extra-nuclear estrogen signaling R-HSA-9009391
Gene expression (Transcription) R-HSA-74160
Negative regulation of the PI3K/AKT network R-HSA-199418
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
Signaling by Nuclear Receptors R-HSA-9006931
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Disease R-HSA-1643685
Nuclear Receptor transcription pathway R-HSA-383280
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI3K/AKT Signaling in Cancer R-HSA-2219528
ESR-mediated signaling R-HSA-8939211
Nuclear Receptor transcription pathway R-HSA-383280
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Generic Transcription Pathway R-HSA-212436
Extra-nuclear estrogen signaling R-HSA-9009391
Negative regulation of the PI3K/AKT network R-HSA-199418
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Signaling by Nuclear Receptors R-HSA-9006931
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Gene expression (Transcription) R-HSA-74160
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Nuclear Receptor transcription pathway R-HSA-383280
ESR-mediated signaling R-HSA-8939211
RNA Polymerase II Transcription R-HSA-73857
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Negative regulation of the PI3K/AKT network R-HSA-199418
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Extra-nuclear estrogen signaling R-HSA-9009391
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
Signaling by Nuclear Receptors R-HSA-9006931
Generic Transcription Pathway R-HSA-212436
ESR-mediated signaling R-HSA-8939211
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Gene expression (Transcription) R-HSA-74160
Negative regulation of the PI3K/AKT network R-HSA-199418
RNA Polymerase II Transcription R-HSA-73857
Intracellular signaling by second messengers R-HSA-9006925
Nuclear Receptor transcription pathway R-HSA-383280
Signaling by Nuclear Receptors R-HSA-9006931
PI3K/AKT Signaling in Cancer R-HSA-2219528
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Extra-nuclear estrogen signaling R-HSA-9009391
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Nuclear Receptors R-HSA-9006931
Gene expression (Transcription) R-HSA-74160
Negative regulation of the PI3K/AKT network R-HSA-199418
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
ESR-mediated signaling R-HSA-8939211
PI3K/AKT Signaling in Cancer R-HSA-2219528
Nuclear Receptor transcription pathway R-HSA-383280
Intracellular signaling by second messengers R-HSA-9006925
Generic Transcription Pathway R-HSA-212436
Extra-nuclear estrogen signaling R-HSA-9009391
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RNA Polymerase II Transcription R-HSA-73857
Negative regulation of the PI3K/AKT network R-HSA-199418
Generic Transcription Pathway R-HSA-212436
Nuclear Receptor transcription pathway R-HSA-383280
PIP3 activates AKT signaling R-HSA-1257604
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Extra-nuclear estrogen signaling R-HSA-9009391
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Disease R-HSA-1643685
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
ESR-mediated signaling R-HSA-8939211
Signaling by Nuclear Receptors R-HSA-9006931
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Nuclear Receptors R-HSA-9006931
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear Receptor transcription pathway R-HSA-383280
Disease R-HSA-1643685
Negative regulation of the PI3K/AKT network R-HSA-199418
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Intracellular signaling by second messengers R-HSA-9006925
ESR-mediated signaling R-HSA-8939211
Generic Transcription Pathway R-HSA-212436
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Extra-nuclear estrogen signaling R-HSA-9009391
Intracellular signaling by second messengers R-HSA-9006925
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Extra-nuclear estrogen signaling R-HSA-9009391
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
Signaling by Nuclear Receptors R-HSA-9006931
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI3K/AKT Signaling in Cancer R-HSA-2219528
RNA Polymerase II Transcription R-HSA-73857
Nuclear Receptor transcription pathway R-HSA-383280
Gene expression (Transcription) R-HSA-74160
Negative regulation of the PI3K/AKT network R-HSA-199418
ESR-mediated signaling R-HSA-8939211
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Extra-nuclear estrogen signaling R-HSA-9009391
Negative regulation of the PI3K/AKT network R-HSA-199418
Nuclear Receptor transcription pathway R-HSA-383280
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Nuclear Receptors R-HSA-9006931
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Gene expression (Transcription) R-HSA-74160
PI3K/AKT Signaling in Cancer R-HSA-2219528
RNA Polymerase II Transcription R-HSA-73857
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
ESR-mediated signaling R-HSA-8939211

Expression Atlas ENSG00000140009
NCBI gene (formerly Entrezgene) 2100
GeneCards 3468
HGNC Symbol HGNC:3468
MIM gene 601663
MIM morbid 618187
UniProtKB Gene Name Q92731
WikiGene 2100
Gene: ESR1
Ensembl ID : ENSG00000091831
Description: estrogen receptor 1
Gene Synonyms: ER-ALPHA,ERA,ESR,NR3A1
45 APIs:
212 Possible Orthologues:

PI3K/AKT Signaling in Cancer R-HSA-2219528
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Transcriptional regulation by RUNX2 R-HSA-8878166
Disease R-HSA-1643685
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Estrogen-dependent gene expression R-HSA-9018519
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nuclear Receptor transcription pathway R-HSA-383280
Deubiquitination R-HSA-5688426
Negative regulation of the PI3K/AKT network R-HSA-199418
Signal Transduction R-HSA-162582
Signaling by ERBB4 R-HSA-1236394
Gene expression (Transcription) R-HSA-74160
ESR-mediated signaling R-HSA-8939211
Extra-nuclear estrogen signaling R-HSA-9009391
Metabolism of proteins R-HSA-392499
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
SUMOylation of intracellular receptors R-HSA-4090294
RNA Polymerase II Transcription R-HSA-73857
Ovarian tumor domain proteases R-HSA-5689896
Post-translational protein modification R-HSA-597592
Generic Transcription Pathway R-HSA-212436
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX1 R-HSA-8878171
SUMOylation R-HSA-2990846
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by Nuclear Receptors R-HSA-9006931
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Nuclear Receptor transcription pathway R-HSA-383280
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Metabolism of proteins R-HSA-392499
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by ERBB4 R-HSA-1236394
SUMOylation of intracellular receptors R-HSA-4090294
Disease R-HSA-1643685
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Extra-nuclear estrogen signaling R-HSA-9009391
Deubiquitination R-HSA-5688426
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
SUMOylation R-HSA-2990846
Negative regulation of the PI3K/AKT network R-HSA-199418
Nuclear signaling by ERBB4 R-HSA-1251985
ESR-mediated signaling R-HSA-8939211
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Generic Transcription Pathway R-HSA-212436
Signaling by Nuclear Receptors R-HSA-9006931
PI3K/AKT Signaling in Cancer R-HSA-2219528
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX2 R-HSA-8878166
RNA Polymerase II Transcription R-HSA-73857
Post-translational protein modification R-HSA-597592
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256
Ovarian tumor domain proteases R-HSA-5689896
Transcriptional regulation by RUNX1 R-HSA-8878171
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987
Estrogen-dependent gene expression R-HSA-9018519
PIP3 activates AKT signaling R-HSA-1257604
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Regulation of RUNX2 expression and activity R-HSA-8939902
Deubiquitination R-HSA-5688426
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Nuclear Receptors R-HSA-9006931
ESR-mediated signaling R-HSA-8939211
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987
Transcriptional regulation by RUNX2 R-HSA-8878166
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
SUMOylation R-HSA-2990846
SUMOylation of intracellular receptors R-HSA-4090294
Extra-nuclear estrogen signaling R-HSA-9009391
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI3K/AKT Signaling in Cancer R-HSA-2219528
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Nuclear signaling by ERBB4 R-HSA-1251985
Negative regulation of the PI3K/AKT network R-HSA-199418
Nuclear Receptor transcription pathway R-HSA-383280
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Intracellular signaling by second messengers R-HSA-9006925
Post-translational protein modification R-HSA-597592
Signal Transduction R-HSA-162582
Estrogen-dependent gene expression R-HSA-9018519
Ovarian tumor domain proteases R-HSA-5689896
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256
Signaling by ERBB4 R-HSA-1236394
Metabolism of proteins R-HSA-392499
Estrogen-dependent gene expression R-HSA-9018519
Deubiquitination R-HSA-5688426
Generic Transcription Pathway R-HSA-212436
Post-translational protein modification R-HSA-597592
Extra-nuclear estrogen signaling R-HSA-9009391
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI3K/AKT Signaling in Cancer R-HSA-2219528
Transcriptional regulation by RUNX1 R-HSA-8878171
ESR-mediated signaling R-HSA-8939211
Intracellular signaling by second messengers R-HSA-9006925
Nuclear signaling by ERBB4 R-HSA-1251985
Transcriptional regulation by RUNX2 R-HSA-8878166
Gene expression (Transcription) R-HSA-74160
Nuclear Receptor transcription pathway R-HSA-383280
Signaling by ERBB4 R-HSA-1236394
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
SUMOylation R-HSA-2990846
SUMOylation of intracellular receptors R-HSA-4090294
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Metabolism of proteins R-HSA-392499
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256
RNA Polymerase II Transcription R-HSA-73857
Ovarian tumor domain proteases R-HSA-5689896
Negative regulation of the PI3K/AKT network R-HSA-199418
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by Nuclear Receptors R-HSA-9006931
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Metabolism of proteins R-HSA-392499
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Gene expression (Transcription) R-HSA-74160
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256
Estrogen-dependent gene expression R-HSA-9018519
RNA Polymerase II Transcription R-HSA-73857
Signaling by ERBB4 R-HSA-1236394
Signaling by Nuclear Receptors R-HSA-9006931
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Regulation of RUNX2 expression and activity R-HSA-8939902
Generic Transcription Pathway R-HSA-212436
ESR-mediated signaling R-HSA-8939211
Transcriptional regulation by RUNX2 R-HSA-8878166
Transcriptional regulation by RUNX1 R-HSA-8878171
SUMOylation R-HSA-2990846
Negative regulation of the PI3K/AKT network R-HSA-199418
Nuclear signaling by ERBB4 R-HSA-1251985
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
SUMOylation of intracellular receptors R-HSA-4090294
Extra-nuclear estrogen signaling R-HSA-9009391
Intracellular signaling by second messengers R-HSA-9006925
Nuclear Receptor transcription pathway R-HSA-383280
Post-translational protein modification R-HSA-597592
PI3K/AKT Signaling in Cancer R-HSA-2219528
Deubiquitination R-HSA-5688426
Signal Transduction R-HSA-162582
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Ovarian tumor domain proteases R-HSA-5689896
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PIP3 activates AKT signaling R-HSA-1257604
Extra-nuclear estrogen signaling R-HSA-9009391
Ovarian tumor domain proteases R-HSA-5689896
Nuclear Receptor transcription pathway R-HSA-383280
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by Nuclear Receptors R-HSA-9006931
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256
Estrogen-dependent gene expression R-HSA-9018519
Metabolism of proteins R-HSA-392499
Deubiquitination R-HSA-5688426
RNA Polymerase II Transcription R-HSA-73857
Signaling by ERBB4 R-HSA-1236394
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI3K/AKT Signaling in Cancer R-HSA-2219528
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Negative regulation of the PI3K/AKT network R-HSA-199418
Nuclear signaling by ERBB4 R-HSA-1251985
SUMOylation R-HSA-2990846
SUMOylation of intracellular receptors R-HSA-4090294
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Gene expression (Transcription) R-HSA-74160
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Transcriptional regulation by RUNX1 R-HSA-8878171
Disease R-HSA-1643685
Regulation of RUNX2 expression and activity R-HSA-8939902
ESR-mediated signaling R-HSA-8939211
Post-translational protein modification R-HSA-597592
Generic Transcription Pathway R-HSA-212436
Negative regulation of the PI3K/AKT network R-HSA-199418
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
ESR-mediated signaling R-HSA-8939211
SUMOylation R-HSA-2990846
Metabolism of proteins R-HSA-392499
Nuclear signaling by ERBB4 R-HSA-1251985
Post-translational protein modification R-HSA-597592
Signal Transduction R-HSA-162582
Signaling by Nuclear Receptors R-HSA-9006931
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256
Generic Transcription Pathway R-HSA-212436
Regulation of RUNX2 expression and activity R-HSA-8939902
Disease R-HSA-1643685
Intracellular signaling by second messengers R-HSA-9006925
RNA Polymerase II Transcription R-HSA-73857
SUMOylation of intracellular receptors R-HSA-4090294
Extra-nuclear estrogen signaling R-HSA-9009391
Ovarian tumor domain proteases R-HSA-5689896
Signaling by ERBB4 R-HSA-1236394
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Deubiquitination R-HSA-5688426
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Estrogen-dependent gene expression R-HSA-9018519
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI3K/AKT Signaling in Cancer R-HSA-2219528
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX2 R-HSA-8878166
Nuclear Receptor transcription pathway R-HSA-383280
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Generic Transcription Pathway R-HSA-212436
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Transcriptional regulation by RUNX1 R-HSA-8878171
Metabolism of proteins R-HSA-392499
Deubiquitination R-HSA-5688426
Estrogen-dependent gene expression R-HSA-9018519
Regulation of RUNX2 expression and activity R-HSA-8939902
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987
Disease R-HSA-1643685
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
SUMOylation of intracellular receptors R-HSA-4090294
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256
Nuclear Receptor transcription pathway R-HSA-383280
RNA Polymerase II Transcription R-HSA-73857
Signaling by Nuclear Receptors R-HSA-9006931
ESR-mediated signaling R-HSA-8939211
Nuclear signaling by ERBB4 R-HSA-1251985
SUMOylation R-HSA-2990846
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of the PI3K/AKT network R-HSA-199418
Ovarian tumor domain proteases R-HSA-5689896
Post-translational protein modification R-HSA-597592
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Extra-nuclear estrogen signaling R-HSA-9009391
Gene expression (Transcription) R-HSA-74160
Signaling by ERBB4 R-HSA-1236394
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Nuclear Receptors R-HSA-9006931
SUMOylation of intracellular receptors R-HSA-4090294
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Signal Transduction R-HSA-162582
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256
Estrogen-dependent gene expression R-HSA-9018519
ESR-mediated signaling R-HSA-8939211
PI3K/AKT Signaling in Cancer R-HSA-2219528
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
SUMOylation R-HSA-2990846
Generic Transcription Pathway R-HSA-212436
Nuclear signaling by ERBB4 R-HSA-1251985
Post-translational protein modification R-HSA-597592
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by ERBB4 R-HSA-1236394
Extra-nuclear estrogen signaling R-HSA-9009391
Nuclear Receptor transcription pathway R-HSA-383280
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional regulation by RUNX1 R-HSA-8878171
Deubiquitination R-HSA-5688426
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Transcriptional regulation by RUNX2 R-HSA-8878166
Ovarian tumor domain proteases R-HSA-5689896
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Metabolism of proteins R-HSA-392499
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987
Negative regulation of the PI3K/AKT network R-HSA-199418
Disease R-HSA-1643685
Post-translational protein modification R-HSA-597592
SUMOylation of intracellular receptors R-HSA-4090294
Nuclear Receptor transcription pathway R-HSA-383280
PI3K/AKT Signaling in Cancer R-HSA-2219528
RNA Polymerase II Transcription R-HSA-73857
Estrogen-dependent gene expression R-HSA-9018519
Intracellular signaling by second messengers R-HSA-9006925
SUMOylation R-HSA-2990846
Deubiquitination R-HSA-5688426
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signal Transduction R-HSA-162582
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987
Metabolism of proteins R-HSA-392499
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Nuclear Receptors R-HSA-9006931
Nuclear signaling by ERBB4 R-HSA-1251985
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256
PIP3 activates AKT signaling R-HSA-1257604
Gene expression (Transcription) R-HSA-74160
ESR-mediated signaling R-HSA-8939211
Regulation of RUNX2 expression and activity R-HSA-8939902
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by ERBB4 R-HSA-1236394
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Transcriptional regulation by RUNX1 R-HSA-8878171
Ovarian tumor domain proteases R-HSA-5689896

Expression Atlas ENSG00000091831
LRG display in Ensembl gene LRG_992
NCBI gene (formerly Entrezgene) 2099
GeneCards 3467
HGNC Symbol HGNC:3467
MIM gene 133430
MIM morbid 615363
UniProtKB Gene Name Q9UE35
WikiGene 2099
Gene: ESRRG
Ensembl ID : ENSG00000196482
Description: estrogen related receptor gamma
Gene Synonyms: ERR-GAMMA,ERRG,NR3B3
1 APIs:
206 Possible Orthologues:

Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Nuclear Receptor transcription pathway R-HSA-383280
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Nuclear Receptor transcription pathway R-HSA-383280
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Nuclear Receptor transcription pathway R-HSA-383280
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Nuclear Receptor transcription pathway R-HSA-383280
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Nuclear Receptor transcription pathway R-HSA-383280
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Nuclear Receptor transcription pathway R-HSA-383280
RNA Polymerase II Transcription R-HSA-73857
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Nuclear Receptor transcription pathway R-HSA-383280
Gene expression (Transcription) R-HSA-74160
Gene expression (Transcription) R-HSA-74160
Nuclear Receptor transcription pathway R-HSA-383280
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Nuclear Receptor transcription pathway R-HSA-383280
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Nuclear Receptor transcription pathway R-HSA-383280
Generic Transcription Pathway R-HSA-212436

Expression Atlas ENSG00000196482
NCBI gene (formerly Entrezgene) 2104
GeneCards 3474
HGNC Symbol HGNC:3474
MIM gene 602969
UniProtKB Gene Name P62508
WikiGene 2104
Gene: NR3C1
Ensembl ID : ENSG00000113580
Description: nuclear receptor subfamily 3 group C member 1
Gene Synonyms: GR,GRL
72 APIs:
280 Possible Orthologues:

Gene expression (Transcription) R-HSA-74160
Signaling by PTK6 R-HSA-8848021
Regulation of NPAS4 gene expression R-HSA-9768759
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
RNA Polymerase II Transcription R-HSA-73857
Disease R-HSA-1643685
SUMOylation R-HSA-2990846
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Transcriptional Regulation by NPAS4 R-HSA-9634815
Post-translational protein modification R-HSA-597592
Circadian Clock R-HSA-400253
Potential therapeutics for SARS R-HSA-9679191
Cellular responses to stress R-HSA-2262752
Regulation of RUNX2 expression and activity R-HSA-8939902
Infectious disease R-HSA-5663205
SUMOylation of intracellular receptors R-HSA-4090294
SARS-CoV Infections R-HSA-9679506
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
FOXO-mediated transcription R-HSA-9614085
Nuclear Receptor transcription pathway R-HSA-383280
Metabolism of proteins R-HSA-392499
Regulation of NPAS4 gene transcription R-HSA-9768777
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
PTK6 Expression R-HSA-8849473
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular responses to stimuli R-HSA-8953897
Regulation of NPAS4 gene expression R-HSA-9768759
SUMOylation R-HSA-2990846
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
SARS-CoV Infections R-HSA-9679506
Metabolism of proteins R-HSA-392499
FOXO-mediated transcription R-HSA-9614085
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
SUMOylation of intracellular receptors R-HSA-4090294
Nuclear Receptor transcription pathway R-HSA-383280
Transcriptional regulation by RUNX2 R-HSA-8878166
Potential therapeutics for SARS R-HSA-9679191
Signaling by PTK6 R-HSA-8848021
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
Regulation of NPAS4 gene transcription R-HSA-9768777
Gene expression (Transcription) R-HSA-74160
Circadian Clock R-HSA-400253
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Cellular responses to stress R-HSA-2262752
RNA Polymerase II Transcription R-HSA-73857
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Generic Transcription Pathway R-HSA-212436
PTK6 Expression R-HSA-8849473
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional Regulation by NPAS4 R-HSA-9634815
Post-translational protein modification R-HSA-597592
Circadian Clock R-HSA-400253
Post-translational protein modification R-HSA-597592
Infectious disease R-HSA-5663205
Metabolism of proteins R-HSA-392499
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by PTK6 R-HSA-8848021
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by NPAS4 R-HSA-9634815
Nuclear Receptor transcription pathway R-HSA-383280
Regulation of NPAS4 gene expression R-HSA-9768759
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
SUMOylation R-HSA-2990846
Cellular responses to stimuli R-HSA-8953897
PTK6 Expression R-HSA-8849473
Signal Transduction R-HSA-162582
SUMOylation of intracellular receptors R-HSA-4090294
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stress R-HSA-2262752
Potential therapeutics for SARS R-HSA-9679191
Regulation of RUNX2 expression and activity R-HSA-8939902
SARS-CoV Infections R-HSA-9679506
Regulation of NPAS4 gene transcription R-HSA-9768777
FOXO-mediated transcription R-HSA-9614085
Gene expression (Transcription) R-HSA-74160
Circadian Clock R-HSA-400253
Metabolism of proteins R-HSA-392499
Generic Transcription Pathway R-HSA-212436
Cellular responses to stimuli R-HSA-8953897
Signaling by PTK6 R-HSA-8848021
Regulation of RUNX2 expression and activity R-HSA-8939902
SUMOylation R-HSA-2990846
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
Nuclear Receptor transcription pathway R-HSA-383280
Regulation of NPAS4 gene transcription R-HSA-9768777
Infectious disease R-HSA-5663205
PTK6 Expression R-HSA-8849473
Post-translational protein modification R-HSA-597592
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Signal Transduction R-HSA-162582
Transcriptional Regulation by NPAS4 R-HSA-9634815
SARS-CoV Infections R-HSA-9679506
SUMOylation of intracellular receptors R-HSA-4090294
Regulation of NPAS4 gene expression R-HSA-9768759
Disease R-HSA-1643685
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Cellular responses to stress R-HSA-2262752
Potential therapeutics for SARS R-HSA-9679191
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
FOXO-mediated transcription R-HSA-9614085
Transcriptional Regulation by NPAS4 R-HSA-9634815
Potential therapeutics for SARS R-HSA-9679191
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
PTK6 Expression R-HSA-8849473
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Infectious disease R-HSA-5663205
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Cellular responses to stress R-HSA-2262752
SUMOylation of intracellular receptors R-HSA-4090294
Regulation of NPAS4 gene expression R-HSA-9768759
Signaling by PTK6 R-HSA-8848021
FOXO-mediated transcription R-HSA-9614085
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
Regulation of NPAS4 gene transcription R-HSA-9768777
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX2 R-HSA-8878166
SUMOylation R-HSA-2990846
Circadian Clock R-HSA-400253
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Nuclear Receptor transcription pathway R-HSA-383280
Cellular responses to stimuli R-HSA-8953897
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism of proteins R-HSA-392499
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
SARS-CoV Infections R-HSA-9679506
Post-translational protein modification R-HSA-597592
Potential therapeutics for SARS R-HSA-9679191
Cellular responses to stress R-HSA-2262752
Circadian Clock R-HSA-400253
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of NPAS4 gene expression R-HSA-9768759
SARS-CoV Infections R-HSA-9679506
Regulation of NPAS4 gene transcription R-HSA-9768777
Infectious disease R-HSA-5663205
RNA Polymerase II Transcription R-HSA-73857
Post-translational protein modification R-HSA-597592
Nuclear Receptor transcription pathway R-HSA-383280
Generic Transcription Pathway R-HSA-212436
SUMOylation R-HSA-2990846
Gene expression (Transcription) R-HSA-74160
SUMOylation of intracellular receptors R-HSA-4090294
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
PTK6 Expression R-HSA-8849473
Metabolism of proteins R-HSA-392499
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
FOXO-mediated transcription R-HSA-9614085
Cellular responses to stimuli R-HSA-8953897
Transcriptional Regulation by NPAS4 R-HSA-9634815
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Signaling by PTK6 R-HSA-8848021
Transcriptional regulation by RUNX2 R-HSA-8878166
Signal Transduction R-HSA-162582
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Disease R-HSA-1643685
Regulation of NPAS4 gene transcription R-HSA-9768777
Cellular responses to stimuli R-HSA-8953897
Regulation of RUNX2 expression and activity R-HSA-8939902
FOXO-mediated transcription R-HSA-9614085
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Transcriptional Regulation by NPAS4 R-HSA-9634815
Signaling by PTK6 R-HSA-8848021
Gene expression (Transcription) R-HSA-74160
Potential therapeutics for SARS R-HSA-9679191
Regulation of NPAS4 gene expression R-HSA-9768759
Nuclear Receptor transcription pathway R-HSA-383280
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
PTK6 Expression R-HSA-8849473
Generic Transcription Pathway R-HSA-212436
SUMOylation of intracellular receptors R-HSA-4090294
Signal Transduction R-HSA-162582
SARS-CoV Infections R-HSA-9679506
Metabolism of proteins R-HSA-392499
Transcriptional regulation by RUNX2 R-HSA-8878166
SUMOylation R-HSA-2990846
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
Post-translational protein modification R-HSA-597592
Circadian Clock R-HSA-400253
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stress R-HSA-2262752
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Cellular responses to stimuli R-HSA-8953897
Regulation of NPAS4 gene transcription R-HSA-9768777
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional Regulation by NPAS4 R-HSA-9634815
Disease R-HSA-1643685
Cellular responses to stress R-HSA-2262752
Post-translational protein modification R-HSA-597592
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of NPAS4 gene expression R-HSA-9768759
Potential therapeutics for SARS R-HSA-9679191
Circadian Clock R-HSA-400253
SUMOylation R-HSA-2990846
Signaling by PTK6 R-HSA-8848021
Generic Transcription Pathway R-HSA-212436
PTK6 Expression R-HSA-8849473
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
FOXO-mediated transcription R-HSA-9614085
SARS-CoV Infections R-HSA-9679506
Nuclear Receptor transcription pathway R-HSA-383280
Metabolism of proteins R-HSA-392499
Infectious disease R-HSA-5663205
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
SUMOylation of intracellular receptors R-HSA-4090294
Disease R-HSA-1643685
RNA Polymerase II Transcription R-HSA-73857
SUMOylation of intracellular receptors R-HSA-4090294
Potential therapeutics for SARS R-HSA-9679191
Nuclear Receptor transcription pathway R-HSA-383280
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Cellular responses to stress R-HSA-2262752
Regulation of RUNX2 expression and activity R-HSA-8939902
Gene expression (Transcription) R-HSA-74160
Transcriptional Regulation by NPAS4 R-HSA-9634815
Signal Transduction R-HSA-162582
SUMOylation R-HSA-2990846
Transcriptional regulation by RUNX2 R-HSA-8878166
Circadian Clock R-HSA-400253
SARS-CoV Infections R-HSA-9679506
Generic Transcription Pathway R-HSA-212436
Post-translational protein modification R-HSA-597592
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
Infectious disease R-HSA-5663205
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Regulation of NPAS4 gene expression R-HSA-9768759
Signaling by PTK6 R-HSA-8848021
FOXO-mediated transcription R-HSA-9614085
Metabolism of proteins R-HSA-392499
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Regulation of NPAS4 gene transcription R-HSA-9768777
PTK6 Expression R-HSA-8849473
Cellular responses to stimuli R-HSA-8953897
Circadian Clock R-HSA-400253
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
SARS-CoV Infections R-HSA-9679506
Nuclear Receptor transcription pathway R-HSA-383280
Post-translational protein modification R-HSA-597592
RNA Polymerase II Transcription R-HSA-73857
Regulation of RUNX2 expression and activity R-HSA-8939902
Infectious disease R-HSA-5663205
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Regulation of NPAS4 gene transcription R-HSA-9768777
SUMOylation of intracellular receptors R-HSA-4090294
Gene expression (Transcription) R-HSA-74160
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Transcriptional Regulation by NPAS4 R-HSA-9634815
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Signaling by PTK6 R-HSA-8848021
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of proteins R-HSA-392499
FOXO-mediated transcription R-HSA-9614085
Regulation of NPAS4 gene expression R-HSA-9768759
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
Potential therapeutics for SARS R-HSA-9679191
SUMOylation R-HSA-2990846
Generic Transcription Pathway R-HSA-212436
PTK6 Expression R-HSA-8849473

Expression Atlas ENSG00000113580
NCBI gene (formerly Entrezgene) 2908
GeneCards 7978
HGNC Symbol HGNC:7978
MIM gene 138040
MIM morbid 615962
UniProtKB Gene Name Q3MSN4
WikiGene 2908