Gene: PSMC1
Ensembl ID : ENSG00000100764
Description: proteasome 26S subunit, ATPase 1
Gene Synonyms: P56,RPT2,S4
5 APIs:
264 Possible Orthologues:

S Phase R-HSA-69242
Stabilization of p53 R-HSA-69541
G2/M Transition R-HSA-69275
Gene expression (Transcription) R-HSA-74160
FCERI mediated NF-kB activation R-HSA-2871837
Metabolism of RNA R-HSA-8953854
Regulation of RAS by GAPs R-HSA-5658442
Deubiquitination R-HSA-5688426
Signaling by NOTCH R-HSA-157118
Transcriptional regulation by RUNX3 R-HSA-8878159
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic Anaphase R-HSA-68882
MAPK family signaling cascades R-HSA-5683057
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Hh mutants are degraded by ERAD R-HSA-5362768
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
Cyclin E associated events during G1/S transition R-HSA-69202
Separation of Sister Chromatids R-HSA-2467813
Hh mutants abrogate ligand secretion R-HSA-5387390
M Phase R-HSA-68886
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
UCH proteinases R-HSA-5689603
Degradation of AXIN R-HSA-4641257
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RUNX2 expression and activity R-HSA-8939902
DNA Replication R-HSA-69306
Antigen processing-Cross presentation R-HSA-1236975
Degradation of DVL R-HSA-4641258
MAPK6/MAPK4 signaling R-HSA-5687128
PTEN Regulation R-HSA-6807070
ABC transporter disorders R-HSA-5619084
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog ligand biogenesis R-HSA-5358346
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Checkpoints R-HSA-69481
Transport of small molecules R-HSA-382551
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Immune System R-HSA-168256
Interleukin-1 family signaling R-HSA-446652
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Adaptive Immune System R-HSA-1280218
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog 'off' state R-HSA-5610787
HIV Infection R-HSA-162906
Signaling by Interleukins R-HSA-449147
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
C-type lectin receptors (CLRs) R-HSA-5621481
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cellular response to hypoxia R-HSA-1234174
Signal Transduction R-HSA-162582
ABC-family proteins mediated transport R-HSA-382556
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
TCF dependent signaling in response to WNT R-HSA-201681
Innate Immune System R-HSA-168249
Cellular response to chemical stress R-HSA-9711123
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Infectious disease R-HSA-5663205
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Nervous system development R-HSA-9675108
G1/S DNA Damage Checkpoints R-HSA-69615
Hedgehog 'on' state R-HSA-5632684
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
Cellular responses to stress R-HSA-2262752
Vif-mediated degradation of APOBEC3G R-HSA-180585
Orc1 removal from chromatin R-HSA-68949
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Developmental Biology R-HSA-1266738
KEAP1-NFE2L2 pathway R-HSA-9755511
Neddylation R-HSA-8951664
Intracellular signaling by second messengers R-HSA-9006925
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism R-HSA-1430728
Degradation of beta-catenin by the destruction complex R-HSA-195253
Downstream TCR signaling R-HSA-202424
Cell Cycle Checkpoints R-HSA-69620
Nuclear events mediated by NFE2L2 R-HSA-9759194
Switching of origins to a post-replicative state R-HSA-69052
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Signaling by Hedgehog R-HSA-5358351
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Axon guidance R-HSA-422475
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle, Mitotic R-HSA-69278
Synthesis of DNA R-HSA-69239
Asparagine N-linked glycosylation R-HSA-446203
Disorders of transmembrane transporters R-HSA-5619115
TCR signaling R-HSA-202403
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Apoptosis R-HSA-109581
Activation of NF-kappaB in B cells R-HSA-1169091
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic G2-G2/M phases R-HSA-453274
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Dependent G1 DNA Damage Response R-HSA-69563
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX2 R-HSA-8878166
Host Interactions of HIV factors R-HSA-162909
Programmed Cell Death R-HSA-5357801
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by ROBO receptors R-HSA-376176
Stabilization of p53 R-HSA-69541
PCP/CE pathway R-HSA-4086400
Interleukin-1 signaling R-HSA-9020702
Cellular responses to stimuli R-HSA-8953897
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by WNT R-HSA-195721
Regulation of mitotic cell cycle R-HSA-453276
ER-Phagosome pathway R-HSA-1236974
Generic Transcription Pathway R-HSA-212436
G2/M Transition R-HSA-69275
DNA Replication Pre-Initiation R-HSA-69002
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of GLI1 by the proteasome R-HSA-5610780
RAF/MAP kinase cascade R-HSA-5673001
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
S Phase R-HSA-69242
G1/S Transition R-HSA-69206
Metabolism of amino acids and derivatives R-HSA-71291
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of PTEN stability and activity R-HSA-8948751
Disease R-HSA-1643685
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of Apoptosis R-HSA-169911
Assembly of the pre-replicative complex R-HSA-68867
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of polyamines R-HSA-351202
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
HIV Infection R-HSA-162906
Disease R-HSA-1643685
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular responses to stimuli R-HSA-8953897
Metabolism R-HSA-1430728
Axon guidance R-HSA-422475
Metabolism of amino acids and derivatives R-HSA-71291
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Developmental Biology R-HSA-1266738
Interleukin-1 family signaling R-HSA-446652
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of polyamines R-HSA-351202
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
RNA Polymerase II Transcription R-HSA-73857
Regulation of mitotic cell cycle R-HSA-453276
Signal Transduction R-HSA-162582
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by Interleukins R-HSA-449147
FCERI mediated NF-kB activation R-HSA-2871837
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Apoptosis R-HSA-109581
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Host Interactions of HIV factors R-HSA-162909
Signaling by Hedgehog R-HSA-5358351
G1/S DNA Damage Checkpoints R-HSA-69615
Defective CFTR causes cystic fibrosis R-HSA-5678895
MAPK1/MAPK3 signaling R-HSA-5684996
Transcriptional regulation by RUNX3 R-HSA-8878159
ER-Phagosome pathway R-HSA-1236974
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by NOTCH R-HSA-157118
Metabolism of proteins R-HSA-392499
Transcriptional regulation by RUNX2 R-HSA-8878166
Hedgehog 'off' state R-HSA-5610787
Regulation of Apoptosis R-HSA-169911
Regulation of RAS by GAPs R-HSA-5658442
Switching of origins to a post-replicative state R-HSA-69052
Nervous system development R-HSA-9675108
Hh mutants are degraded by ERAD R-HSA-5362768
Post-translational protein modification R-HSA-597592
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of DVL R-HSA-4641258
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of beta-catenin by the destruction complex R-HSA-195253
DNA Replication R-HSA-69306
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Gene expression (Transcription) R-HSA-74160
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
M Phase R-HSA-68886
G1/S Transition R-HSA-69206
Beta-catenin independent WNT signaling R-HSA-3858494
Assembly of the pre-replicative complex R-HSA-68867
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of RUNX2 expression and activity R-HSA-8939902
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of GLI2 by the proteasome R-HSA-5610783
Cellular response to chemical stress R-HSA-9711123
Degradation of AXIN R-HSA-4641257
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Immune System R-HSA-168256
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cellular responses to stress R-HSA-2262752
RAF/MAP kinase cascade R-HSA-5673001
Orc1 removal from chromatin R-HSA-68949
Cell Cycle R-HSA-1640170
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Separation of Sister Chromatids R-HSA-2467813
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
G2/M Transition R-HSA-69275
Signaling by NOTCH4 R-HSA-9013694
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Disorders of transmembrane transporters R-HSA-5619115
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G2/M Checkpoints R-HSA-69481
Cell Cycle, Mitotic R-HSA-69278
Asparagine N-linked glycosylation R-HSA-446203
PIP3 activates AKT signaling R-HSA-1257604
Signaling by ROBO receptors R-HSA-376176
Cellular response to hypoxia R-HSA-1234174
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Downstream TCR signaling R-HSA-202424
Innate Immune System R-HSA-168249
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK6/MAPK4 signaling R-HSA-5687128
Transport of small molecules R-HSA-382551
Cell Cycle Checkpoints R-HSA-69620
Transcriptional regulation by RUNX1 R-HSA-8878171
Generic Transcription Pathway R-HSA-212436
Adaptive Immune System R-HSA-1280218
ABC-family proteins mediated transport R-HSA-382556
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
UCH proteinases R-HSA-5689603
MAPK family signaling cascades R-HSA-5683057
ABC transporter disorders R-HSA-5619084
Hh mutants abrogate ligand secretion R-HSA-5387390
PCP/CE pathway R-HSA-4086400
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic G2-G2/M phases R-HSA-453274
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Mitotic Anaphase R-HSA-68882
PTEN Regulation R-HSA-6807070
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
KEAP1-NFE2L2 pathway R-HSA-9755511
Class I MHC mediated antigen processing & presentation R-HSA-983169
Infectious disease R-HSA-5663205
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
TCR signaling R-HSA-202403
Negative regulation of NOTCH4 signaling R-HSA-9604323
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Metabolism of RNA R-HSA-8953854
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Vpu mediated degradation of CD4 R-HSA-180534
Intracellular signaling by second messengers R-HSA-9006925
Stabilization of p53 R-HSA-69541
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
DNA Replication Pre-Initiation R-HSA-69002
Hedgehog 'on' state R-HSA-5632684
Antigen processing-Cross presentation R-HSA-1236975
Nuclear events mediated by NFE2L2 R-HSA-9759194
Programmed Cell Death R-HSA-5357801
Mitotic G1 phase and G1/S transition R-HSA-453279
Ub-specific processing proteases R-HSA-5689880
Deubiquitination R-HSA-5688426
Neddylation R-HSA-8951664
Interleukin-1 signaling R-HSA-9020702
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Synthesis of DNA R-HSA-69239
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by WNT R-HSA-195721
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Independent DNA Damage Response R-HSA-69610
Asymmetric localization of PCP proteins R-HSA-4608870
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of GLI1 by the proteasome R-HSA-5610780
Vif-mediated degradation of APOBEC3G R-HSA-180585
Hedgehog ligand biogenesis R-HSA-5358346
Separation of Sister Chromatids R-HSA-2467813
MAPK6/MAPK4 signaling R-HSA-5687128
Cell Cycle R-HSA-1640170
Degradation of DVL R-HSA-4641258
Deubiquitination R-HSA-5688426
MAPK family signaling cascades R-HSA-5683057
G2/M Transition R-HSA-69275
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signal Transduction R-HSA-162582
Activation of NF-kappaB in B cells R-HSA-1169091
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RAF/MAP kinase cascade R-HSA-5673001
PTEN Regulation R-HSA-6807070
M Phase R-HSA-68886
Transcriptional regulation by RUNX2 R-HSA-8878166
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of RAS by GAPs R-HSA-5658442
Vpu mediated degradation of CD4 R-HSA-180534
FCERI mediated NF-kB activation R-HSA-2871837
Downstream TCR signaling R-HSA-202424
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCF dependent signaling in response to WNT R-HSA-201681
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of amino acids and derivatives R-HSA-71291
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of mitotic cell cycle R-HSA-453276
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Neddylation R-HSA-8951664
TCR signaling R-HSA-202403
Mitotic G2-G2/M phases R-HSA-453274
KEAP1-NFE2L2 pathway R-HSA-9755511
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Class I MHC mediated antigen processing & presentation R-HSA-983169
DNA Replication R-HSA-69306
Innate Immune System R-HSA-168249
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
UCH proteinases R-HSA-5689603
Disease R-HSA-1643685
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Intracellular signaling by second messengers R-HSA-9006925
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
MAPK1/MAPK3 signaling R-HSA-5684996
Nuclear events mediated by NFE2L2 R-HSA-9759194
Interleukin-1 signaling R-HSA-9020702
PCP/CE pathway R-HSA-4086400
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transport of small molecules R-HSA-382551
Apoptosis R-HSA-109581
Ub-specific processing proteases R-HSA-5689880
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Metabolism of RNA R-HSA-8953854
Hedgehog 'off' state R-HSA-5610787
ABC transporter disorders R-HSA-5619084
Interleukin-1 family signaling R-HSA-446652
Antigen processing-Cross presentation R-HSA-1236975
Regulation of PTEN stability and activity R-HSA-8948751
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
Regulation of Apoptosis R-HSA-169911
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Negative regulation of NOTCH4 signaling R-HSA-9604323
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of RUNX3 expression and activity R-HSA-8941858
Immune System R-HSA-168256
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Assembly of the pre-replicative complex R-HSA-68867
Transcriptional regulation by RUNX3 R-HSA-8878159
Infectious disease R-HSA-5663205
Cell Cycle Checkpoints R-HSA-69620
Axon guidance R-HSA-422475
Cellular response to hypoxia R-HSA-1234174
PIP3 activates AKT signaling R-HSA-1257604
S Phase R-HSA-69242
Degradation of GLI1 by the proteasome R-HSA-5610780
Host Interactions of HIV factors R-HSA-162909
Disorders of transmembrane transporters R-HSA-5619115
Cytokine Signaling in Immune system R-HSA-1280215
Generic Transcription Pathway R-HSA-212436
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Asparagine N-linked glycosylation R-HSA-446203
HIV Infection R-HSA-162906
Cell Cycle, Mitotic R-HSA-69278
Orc1 removal from chromatin R-HSA-68949
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of polyamines R-HSA-351202
Synthesis of DNA R-HSA-69239
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transcriptional regulation by RUNX1 R-HSA-8878171
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Mitotic G1 phase and G1/S transition R-HSA-453279
Developmental Biology R-HSA-1266738
G1/S DNA Damage Checkpoints R-HSA-69615
Asymmetric localization of PCP proteins R-HSA-4608870
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Switching of origins to a post-replicative state R-HSA-69052
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by NOTCH4 R-HSA-9013694
Mitotic Metaphase and Anaphase R-HSA-2555396
Programmed Cell Death R-HSA-5357801
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism of proteins R-HSA-392499
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism R-HSA-1430728
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of GLI2 by the proteasome R-HSA-5610783
Degradation of beta-catenin by the destruction complex R-HSA-195253
Adaptive Immune System R-HSA-1280218
G2/M Checkpoints R-HSA-69481
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by NOTCH R-HSA-157118
C-type lectin receptors (CLRs) R-HSA-5621481
RNA Polymerase II Transcription R-HSA-73857
ER-Phagosome pathway R-HSA-1236974
Degradation of AXIN R-HSA-4641257
Mitotic Anaphase R-HSA-68882
G1/S Transition R-HSA-69206
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
Vif-mediated degradation of APOBEC3G R-HSA-180585
Hh mutants are degraded by ERAD R-HSA-5362768
Post-translational protein modification R-HSA-597592
ABC-family proteins mediated transport R-HSA-382556
Signaling by ROBO receptors R-HSA-376176
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stress R-HSA-2262752
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by WNT R-HSA-195721
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular response to chemical stress R-HSA-9711123
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by Hedgehog R-HSA-5358351
DNA Replication Pre-Initiation R-HSA-69002
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Dependent G1 DNA Damage Response R-HSA-69563
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Nervous system development R-HSA-9675108
p53-Independent DNA Damage Response R-HSA-69610
Cellular responses to stimuli R-HSA-8953897
Regulation of RUNX2 expression and activity R-HSA-8939902
Hedgehog 'on' state R-HSA-5632684
Signal Transduction R-HSA-162582
Assembly of the pre-replicative complex R-HSA-68867
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Asymmetric localization of PCP proteins R-HSA-4608870
Generic Transcription Pathway R-HSA-212436
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Axon guidance R-HSA-422475
Disease R-HSA-1643685
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by NOTCH4 R-HSA-9013694
Host Interactions of HIV factors R-HSA-162909
MAPK6/MAPK4 signaling R-HSA-5687128
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of proteins R-HSA-392499
TCR signaling R-HSA-202403
Immune System R-HSA-168256
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hedgehog 'off' state R-HSA-5610787
Negative regulation of NOTCH4 signaling R-HSA-9604323
Nervous system development R-HSA-9675108
Signaling by WNT R-HSA-195721
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
FCERI mediated NF-kB activation R-HSA-2871837
Separation of Sister Chromatids R-HSA-2467813
G1/S Transition R-HSA-69206
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
CLEC7A (Dectin-1) signaling R-HSA-5607764
Synthesis of DNA R-HSA-69239
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle Checkpoints R-HSA-69620
Downstream TCR signaling R-HSA-202424
Switching of origins to a post-replicative state R-HSA-69052
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
C-type lectin receptors (CLRs) R-HSA-5621481
PCP/CE pathway R-HSA-4086400
Orc1 removal from chromatin R-HSA-68949
RAF/MAP kinase cascade R-HSA-5673001
Degradation of GLI1 by the proteasome R-HSA-5610780
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication Pre-Initiation R-HSA-69002
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
DNA Replication R-HSA-69306
UCH proteinases R-HSA-5689603
PIP3 activates AKT signaling R-HSA-1257604
Cellular responses to stimuli R-HSA-8953897
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Neddylation R-HSA-8951664
Cell Cycle, Mitotic R-HSA-69278
Signaling by NOTCH R-HSA-157118
ER-Phagosome pathway R-HSA-1236974
Transcriptional regulation by RUNX1 R-HSA-8878171
Metabolism R-HSA-1430728
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Antigen processing-Cross presentation R-HSA-1236975
Infectious disease R-HSA-5663205
Mitotic Anaphase R-HSA-68882
G2/M Checkpoints R-HSA-69481
Regulation of RUNX2 expression and activity R-HSA-8939902
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of mitotic cell cycle R-HSA-453276
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Apoptosis R-HSA-109581
Metabolism of polyamines R-HSA-351202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Disorders of transmembrane transporters R-HSA-5619115
PTEN Regulation R-HSA-6807070
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular response to chemical stress R-HSA-9711123
M Phase R-HSA-68886
G2/M Transition R-HSA-69275
Post-translational protein modification R-HSA-597592
Interleukin-1 signaling R-HSA-9020702
Developmental Biology R-HSA-1266738
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Adaptive Immune System R-HSA-1280218
S Phase R-HSA-69242
Degradation of AXIN R-HSA-4641257
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Programmed Cell Death R-HSA-5357801
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog 'on' state R-HSA-5632684
Asparagine N-linked glycosylation R-HSA-446203
Deubiquitination R-HSA-5688426
Degradation of DVL R-HSA-4641258
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of GLI2 by the proteasome R-HSA-5610783
Innate Immune System R-HSA-168249
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 family signaling R-HSA-446652
Mitotic Metaphase and Anaphase R-HSA-2555396
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ABC-family proteins mediated transport R-HSA-382556
Metabolism of RNA R-HSA-8953854
Gene expression (Transcription) R-HSA-74160
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
HIV Infection R-HSA-162906
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Transcriptional regulation by RUNX3 R-HSA-8878159
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Vpu mediated degradation of CD4 R-HSA-180534
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
RNA Polymerase II Transcription R-HSA-73857
Regulation of RAS by GAPs R-HSA-5658442
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle R-HSA-1640170
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hedgehog ligand biogenesis R-HSA-5358346
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by ROBO receptors R-HSA-376176
Ub-specific processing proteases R-HSA-5689880
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Defective CFTR causes cystic fibrosis R-HSA-5678895
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of Apoptosis R-HSA-169911
Signaling by the B Cell Receptor (BCR) R-HSA-983705
KEAP1-NFE2L2 pathway R-HSA-9755511
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hh mutants abrogate ligand secretion R-HSA-5387390
Stabilization of p53 R-HSA-69541
ABC transporter disorders R-HSA-5619084
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK family signaling cascades R-HSA-5683057
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transcriptional regulation by RUNX2 R-HSA-8878166
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
TCF dependent signaling in response to WNT R-HSA-201681
Transport of small molecules R-HSA-382551
p53-Independent DNA Damage Response R-HSA-69610
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by Hedgehog R-HSA-5358351
Regulation of RUNX3 expression and activity R-HSA-8941858
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cellular responses to stress R-HSA-2262752
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by Interleukins R-HSA-449147
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of amino acids and derivatives R-HSA-71291
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle R-HSA-1640170
Adaptive Immune System R-HSA-1280218
Hedgehog 'on' state R-HSA-5632684
PTEN Regulation R-HSA-6807070
TCF dependent signaling in response to WNT R-HSA-201681
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of DVL R-HSA-4641258
Asymmetric localization of PCP proteins R-HSA-4608870
KEAP1-NFE2L2 pathway R-HSA-9755511
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of Apoptosis R-HSA-169911
MAPK1/MAPK3 signaling R-HSA-5684996
Hh mutants abrogate ligand secretion R-HSA-5387390
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of proteins R-HSA-392499
Mitotic Metaphase and Anaphase R-HSA-2555396
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cellular responses to stress R-HSA-2262752
Switching of origins to a post-replicative state R-HSA-69052
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH4 R-HSA-9013694
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle, Mitotic R-HSA-69278
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of RNA R-HSA-8953854
Post-translational protein modification R-HSA-597592
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by WNT R-HSA-195721
Ub-specific processing proteases R-HSA-5689880
Hedgehog ligand biogenesis R-HSA-5358346
Developmental Biology R-HSA-1266738
p53-Dependent G1 DNA Damage Response R-HSA-69563
Innate Immune System R-HSA-168249
Assembly of the pre-replicative complex R-HSA-68867
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
HIV Infection R-HSA-162906
Generic Transcription Pathway R-HSA-212436
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Orc1 removal from chromatin R-HSA-68949
Disease R-HSA-1643685
Axon guidance R-HSA-422475
Stabilization of p53 R-HSA-69541
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Hedgehog 'off' state R-HSA-5610787
Nervous system development R-HSA-9675108
Gene expression (Transcription) R-HSA-74160
Cellular response to hypoxia R-HSA-1234174
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism R-HSA-1430728
PCP/CE pathway R-HSA-4086400
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Transport of small molecules R-HSA-382551
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Transcriptional regulation by RUNX3 R-HSA-8878159
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular responses to stimuli R-HSA-8953897
Disorders of transmembrane transporters R-HSA-5619115
Interleukin-1 signaling R-HSA-9020702
Signaling by ROBO receptors R-HSA-376176
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
PIP3 activates AKT signaling R-HSA-1257604
Regulation of mitotic cell cycle R-HSA-453276
G2/M Transition R-HSA-69275
Mitotic Anaphase R-HSA-68882
Class I MHC mediated antigen processing & presentation R-HSA-983169
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
CLEC7A (Dectin-1) signaling R-HSA-5607764
DNA Replication R-HSA-69306
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Independent DNA Damage Response R-HSA-69610
Infectious disease R-HSA-5663205
Intracellular signaling by second messengers R-HSA-9006925
G2/M Checkpoints R-HSA-69481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Immune System R-HSA-168256
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Neddylation R-HSA-8951664
Cellular response to chemical stress R-HSA-9711123
Synthesis of DNA R-HSA-69239
Asparagine N-linked glycosylation R-HSA-446203
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
RNA Polymerase II Transcription R-HSA-73857
ER-Phagosome pathway R-HSA-1236974
Deubiquitination R-HSA-5688426
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of polyamines R-HSA-351202
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hh mutants are degraded by ERAD R-HSA-5362768
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G1 phase and G1/S transition R-HSA-453279
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Degradation of AXIN R-HSA-4641257
Host Interactions of HIV factors R-HSA-162909
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
UCH proteinases R-HSA-5689603
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Separation of Sister Chromatids R-HSA-2467813
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of PTEN stability and activity R-HSA-8948751
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
ABC-family proteins mediated transport R-HSA-382556
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by Hedgehog R-HSA-5358351
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
FCERI mediated NF-kB activation R-HSA-2871837
M Phase R-HSA-68886
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of GLI2 by the proteasome R-HSA-5610783
Programmed Cell Death R-HSA-5357801
Cell Cycle Checkpoints R-HSA-69620
TCR signaling R-HSA-202403
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
C-type lectin receptors (CLRs) R-HSA-5621481
Apoptosis R-HSA-109581
RAF/MAP kinase cascade R-HSA-5673001
Defective CFTR causes cystic fibrosis R-HSA-5678895
S Phase R-HSA-69242
Signal Transduction R-HSA-162582
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cytokine Signaling in Immune system R-HSA-1280215
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK family signaling cascades R-HSA-5683057
Downstream TCR signaling R-HSA-202424
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S Transition R-HSA-69206
ABC transporter disorders R-HSA-5619084
Cyclin E associated events during G1/S transition R-HSA-69202
Interleukin-1 family signaling R-HSA-446652
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by Interleukins R-HSA-449147
Asymmetric localization of PCP proteins R-HSA-4608870
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signal Transduction R-HSA-162582
KEAP1-NFE2L2 pathway R-HSA-9755511
Neddylation R-HSA-8951664
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Infectious disease R-HSA-5663205
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of amino acids and derivatives R-HSA-71291
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
Cell Cycle Checkpoints R-HSA-69620
C-type lectin receptors (CLRs) R-HSA-5621481
Mitotic G1 phase and G1/S transition R-HSA-453279
ABC-family proteins mediated transport R-HSA-382556
Deubiquitination R-HSA-5688426
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism of proteins R-HSA-392499
S Phase R-HSA-69242
Disease R-HSA-1643685
Cyclin E associated events during G1/S transition R-HSA-69202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of Apoptosis R-HSA-169911
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
Cellular response to chemical stress R-HSA-9711123
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Innate Immune System R-HSA-168249
CLEC7A (Dectin-1) signaling R-HSA-5607764
Activation of NF-kappaB in B cells R-HSA-1169091
Vpu mediated degradation of CD4 R-HSA-180534
Negative regulation of NOTCH4 signaling R-HSA-9604323
Adaptive Immune System R-HSA-1280218
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cytokine Signaling in Immune system R-HSA-1280215
Cell Cycle, Mitotic R-HSA-69278
G1/S Transition R-HSA-69206
Asparagine N-linked glycosylation R-HSA-446203
Metabolism R-HSA-1430728
MAPK1/MAPK3 signaling R-HSA-5684996
Developmental Biology R-HSA-1266738
Metabolism of RNA R-HSA-8953854
TCF dependent signaling in response to WNT R-HSA-201681
Interleukin-1 family signaling R-HSA-446652
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog 'on' state R-HSA-5632684
MAPK family signaling cascades R-HSA-5683057
Signaling by Hedgehog R-HSA-5358351
Intracellular signaling by second messengers R-HSA-9006925
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RUNX3 expression and activity R-HSA-8941858
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Separation of Sister Chromatids R-HSA-2467813
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
G2/M Checkpoints R-HSA-69481
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
G2/M Transition R-HSA-69275
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by ROBO receptors R-HSA-376176
Assembly of the pre-replicative complex R-HSA-68867
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Transcriptional regulation by RUNX2 R-HSA-8878166
Transport of small molecules R-HSA-382551
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Axon guidance R-HSA-422475
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Apoptosis R-HSA-109581
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular responses to stimuli R-HSA-8953897
Ub-specific processing proteases R-HSA-5689880
TCR signaling R-HSA-202403
Antigen processing-Cross presentation R-HSA-1236975
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular responses to stress R-HSA-2262752
Switching of origins to a post-replicative state R-HSA-69052
Post-translational protein modification R-HSA-597592
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Beta-catenin independent WNT signaling R-HSA-3858494
Hh mutants abrogate ligand secretion R-HSA-5387390
ABC transporter disorders R-HSA-5619084
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Degradation of DVL R-HSA-4641258
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RAF/MAP kinase cascade R-HSA-5673001
Transcriptional regulation by RUNX1 R-HSA-8878171
Orc1 removal from chromatin R-HSA-68949
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Independent DNA Damage Response R-HSA-69610
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Synthesis of DNA R-HSA-69239
M Phase R-HSA-68886
PTEN Regulation R-HSA-6807070
Host Interactions of HIV factors R-HSA-162909
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Degradation of GLI2 by the proteasome R-HSA-5610783
Stabilization of p53 R-HSA-69541
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Mitotic Anaphase R-HSA-68882
DNA Replication R-HSA-69306
G1/S DNA Damage Checkpoints R-HSA-69615
ER-Phagosome pathway R-HSA-1236974
Signaling by NOTCH R-HSA-157118
DNA Replication Pre-Initiation R-HSA-69002
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Immune System R-HSA-168256
Programmed Cell Death R-HSA-5357801
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of PTEN stability and activity R-HSA-8948751
Disorders of transmembrane transporters R-HSA-5619115
Regulation of mitotic cell cycle R-HSA-453276
Degradation of beta-catenin by the destruction complex R-HSA-195253
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Interleukin-1 signaling R-HSA-9020702
FCERI mediated NF-kB activation R-HSA-2871837
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by Interleukins R-HSA-449147
Signaling by WNT R-HSA-195721
Cell Cycle R-HSA-1640170
PCP/CE pathway R-HSA-4086400
Cellular response to hypoxia R-HSA-1234174
UCH proteinases R-HSA-5689603
Degradation of AXIN R-HSA-4641257
Class I MHC mediated antigen processing & presentation R-HSA-983169
Defective CFTR causes cystic fibrosis R-HSA-5678895
HIV Infection R-HSA-162906
Regulation of RAS by GAPs R-HSA-5658442
Downstream TCR signaling R-HSA-202424
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
Degradation of GLI1 by the proteasome R-HSA-5610780
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of polyamines R-HSA-351202
RNA Polymerase II Transcription R-HSA-73857
Regulation of RUNX2 expression and activity R-HSA-8939902
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hedgehog 'off' state R-HSA-5610787
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Asparagine N-linked glycosylation R-HSA-446203
Hedgehog ligand biogenesis R-HSA-5358346
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular response to chemical stress R-HSA-9711123
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metabolism of proteins R-HSA-392499
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by Hedgehog R-HSA-5358351
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cell Cycle Checkpoints R-HSA-69620
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Vif-mediated degradation of APOBEC3G R-HSA-180585
Class I MHC mediated antigen processing & presentation R-HSA-983169
PTEN Regulation R-HSA-6807070
Metabolism R-HSA-1430728
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of polyamines R-HSA-351202
Axon guidance R-HSA-422475
S Phase R-HSA-69242
PIP3 activates AKT signaling R-HSA-1257604
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by ROBO receptors R-HSA-376176
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of DVL R-HSA-4641258
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Assembly of the pre-replicative complex R-HSA-68867
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog 'on' state R-HSA-5632684
Downstream TCR signaling R-HSA-202424
Cyclin E associated events during G1/S transition R-HSA-69202
Mitotic G1 phase and G1/S transition R-HSA-453279
Vpu mediated degradation of CD4 R-HSA-180534
Asymmetric localization of PCP proteins R-HSA-4608870
Synthesis of DNA R-HSA-69239
Degradation of GLI2 by the proteasome R-HSA-5610783
KEAP1-NFE2L2 pathway R-HSA-9755511
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Mitotic Anaphase R-HSA-68882
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Deubiquitination R-HSA-5688426
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Mitotic G2-G2/M phases R-HSA-453274
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signal Transduction R-HSA-162582
Innate Immune System R-HSA-168249
Ub-specific processing proteases R-HSA-5689880
Hh mutants abrogate ligand secretion R-HSA-5387390
Separation of Sister Chromatids R-HSA-2467813
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
TCR signaling R-HSA-202403
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of mitotic cell cycle R-HSA-453276
Neddylation R-HSA-8951664
Metabolism of amino acids and derivatives R-HSA-71291
M Phase R-HSA-68886
Gene expression (Transcription) R-HSA-74160
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G1/S Transition R-HSA-69206
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by Interleukins R-HSA-449147
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by NOTCH R-HSA-157118
Programmed Cell Death R-HSA-5357801
Interleukin-1 family signaling R-HSA-446652
Transcriptional regulation by RUNX2 R-HSA-8878166
RAF/MAP kinase cascade R-HSA-5673001
ABC transporter disorders R-HSA-5619084
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RNA Polymerase II Transcription R-HSA-73857
DNA Replication R-HSA-69306
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Mitotic Metaphase and Anaphase R-HSA-2555396
Developmental Biology R-HSA-1266738
Cellular responses to stress R-HSA-2262752
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transport of small molecules R-HSA-382551
DNA Replication Pre-Initiation R-HSA-69002
Nuclear events mediated by NFE2L2 R-HSA-9759194
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
UCH proteinases R-HSA-5689603
Immune System R-HSA-168256
HIV Infection R-HSA-162906
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Hedgehog 'off' state R-HSA-5610787
Regulation of PTEN stability and activity R-HSA-8948751
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
MAPK6/MAPK4 signaling R-HSA-5687128
Post-translational protein modification R-HSA-597592
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of RNA R-HSA-8953854
Generic Transcription Pathway R-HSA-212436
PCP/CE pathway R-HSA-4086400
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to hypoxia R-HSA-1234174
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
G2/M Checkpoints R-HSA-69481
TCF dependent signaling in response to WNT R-HSA-201681
G1/S DNA Damage Checkpoints R-HSA-69615
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Apoptosis R-HSA-109581
Cellular responses to stimuli R-HSA-8953897
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RAS by GAPs R-HSA-5658442
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Signaling by NOTCH4 R-HSA-9013694
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cell Cycle R-HSA-1640170
Disorders of transmembrane transporters R-HSA-5619115
Interleukin-1 signaling R-HSA-9020702
Signaling by WNT R-HSA-195721
G2/M Transition R-HSA-69275
Orc1 removal from chromatin R-HSA-68949
Regulation of RUNX2 expression and activity R-HSA-8939902
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
Adaptive Immune System R-HSA-1280218
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
ER-Phagosome pathway R-HSA-1236974
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Independent DNA Damage Response R-HSA-69610
ABC-family proteins mediated transport R-HSA-382556
Degradation of AXIN R-HSA-4641257
Host Interactions of HIV factors R-HSA-162909
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Regulation of Apoptosis R-HSA-169911
Transcriptional regulation by RUNX3 R-HSA-8878159
Nervous system development R-HSA-9675108
Cell Cycle, Mitotic R-HSA-69278
Degradation of GLI1 by the proteasome R-HSA-5610780
Switching of origins to a post-replicative state R-HSA-69052
Negative regulation of NOTCH4 signaling R-HSA-9604323
Transcriptional regulation by RUNX1 R-HSA-8878171
Interleukin-1 signaling R-HSA-9020702
Hedgehog ligand biogenesis R-HSA-5358346
Cellular response to chemical stress R-HSA-9711123
Regulation of mitotic cell cycle R-HSA-453276
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Independent DNA Damage Response R-HSA-69610
Innate Immune System R-HSA-168249
Signaling by ROBO receptors R-HSA-376176
Stabilization of p53 R-HSA-69541
Signaling by Interleukins R-HSA-449147
MAPK family signaling cascades R-HSA-5683057
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Developmental Biology R-HSA-1266738
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Hedgehog R-HSA-5358351
Regulation of RUNX3 expression and activity R-HSA-8941858
Mitotic Anaphase R-HSA-68882
RAF/MAP kinase cascade R-HSA-5673001
Regulation of Apoptosis R-HSA-169911
Downstream TCR signaling R-HSA-202424
Disease R-HSA-1643685
Mitotic Metaphase and Anaphase R-HSA-2555396
Nervous system development R-HSA-9675108
ER-Phagosome pathway R-HSA-1236974
C-type lectin receptors (CLRs) R-HSA-5621481
Beta-catenin independent WNT signaling R-HSA-3858494
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
UCH proteinases R-HSA-5689603
Transcriptional regulation by RUNX1 R-HSA-8878171
ABC-family proteins mediated transport R-HSA-382556
Cytokine Signaling in Immune system R-HSA-1280215
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism R-HSA-1430728
Cellular responses to stress R-HSA-2262752
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of AXIN R-HSA-4641257
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Neddylation R-HSA-8951664
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PCP/CE pathway R-HSA-4086400
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Ub-specific processing proteases R-HSA-5689880
Immune System R-HSA-168256
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Adaptive Immune System R-HSA-1280218
Generic Transcription Pathway R-HSA-212436
G2/M Checkpoints R-HSA-69481
DNA Replication Pre-Initiation R-HSA-69002
Transcriptional regulation by RUNX2 R-HSA-8878166
Transcriptional regulation by RUNX3 R-HSA-8878159
Defective CFTR causes cystic fibrosis R-HSA-5678895
Intracellular signaling by second messengers R-HSA-9006925
Mitotic G2-G2/M phases R-HSA-453274
Apoptosis R-HSA-109581
p53-Dependent G1 DNA Damage Response R-HSA-69563
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cyclin E associated events during G1/S transition R-HSA-69202
Asymmetric localization of PCP proteins R-HSA-4608870
Orc1 removal from chromatin R-HSA-68949
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by WNT R-HSA-195721
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hh mutants abrogate ligand secretion R-HSA-5387390
Activation of NF-kappaB in B cells R-HSA-1169091
Asparagine N-linked glycosylation R-HSA-446203
Host Interactions of HIV factors R-HSA-162909
Degradation of DVL R-HSA-4641258
MAPK6/MAPK4 signaling R-HSA-5687128
Vpu mediated degradation of CD4 R-HSA-180534
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of GLI2 by the proteasome R-HSA-5610783
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of GLI1 by the proteasome R-HSA-5610780
Cell Cycle R-HSA-1640170
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
M Phase R-HSA-68886
Antigen processing-Cross presentation R-HSA-1236975
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by NOTCH4 R-HSA-9013694
Hh mutants are degraded by ERAD R-HSA-5362768
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Assembly of the pre-replicative complex R-HSA-68867
S Phase R-HSA-69242
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
DNA Replication R-HSA-69306
Deubiquitination R-HSA-5688426
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of RNA R-HSA-8953854
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular responses to stimuli R-HSA-8953897
Disorders of transmembrane transporters R-HSA-5619115
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Programmed Cell Death R-HSA-5357801
HIV Infection R-HSA-162906
Signaling by NOTCH R-HSA-157118
PTEN Regulation R-HSA-6807070
Axon guidance R-HSA-422475
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S DNA Damage Checkpoints R-HSA-69615
ABC transporter disorders R-HSA-5619084
Interleukin-1 family signaling R-HSA-446652
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of PTEN stability and activity R-HSA-8948751
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RAS by GAPs R-HSA-5658442
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transport of small molecules R-HSA-382551
Synthesis of DNA R-HSA-69239
G1/S Transition R-HSA-69206
Cellular response to hypoxia R-HSA-1234174
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic G1 phase and G1/S transition R-HSA-453279
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cell Cycle, Mitotic R-HSA-69278
Vif-mediated degradation of APOBEC3G R-HSA-180585
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Metabolism of proteins R-HSA-392499
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
RNA Polymerase II Transcription R-HSA-73857
KEAP1-NFE2L2 pathway R-HSA-9755511
Hedgehog 'on' state R-HSA-5632684
CLEC7A (Dectin-1) signaling R-HSA-5607764
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
TCR signaling R-HSA-202403
Cell Cycle Checkpoints R-HSA-69620
Regulation of RUNX2 expression and activity R-HSA-8939902
Infectious disease R-HSA-5663205
Metabolism of polyamines R-HSA-351202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog 'off' state R-HSA-5610787
Switching of origins to a post-replicative state R-HSA-69052
Separation of Sister Chromatids R-HSA-2467813
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Defective CFTR causes cystic fibrosis R-HSA-5678895
TCF dependent signaling in response to WNT R-HSA-201681
Developmental Biology R-HSA-1266738
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cellular responses to stimuli R-HSA-8953897
Degradation of AXIN R-HSA-4641257
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Deubiquitination R-HSA-5688426
Regulation of RAS by GAPs R-HSA-5658442
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by NOTCH4 R-HSA-9013694
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
Signaling by ROBO receptors R-HSA-376176
Disease R-HSA-1643685
Degradation of DVL R-HSA-4641258
Adaptive Immune System R-HSA-1280218
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hedgehog 'on' state R-HSA-5632684
DNA Replication R-HSA-69306
PCP/CE pathway R-HSA-4086400
Neddylation R-HSA-8951664
MAPK6/MAPK4 signaling R-HSA-5687128
M Phase R-HSA-68886
Hh mutants abrogate ligand secretion R-HSA-5387390
Disorders of transmembrane transporters R-HSA-5619115
Axon guidance R-HSA-422475
Signaling by WNT R-HSA-195721
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Degradation of beta-catenin by the destruction complex R-HSA-195253
Orc1 removal from chromatin R-HSA-68949
Stabilization of p53 R-HSA-69541
Intracellular signaling by second messengers R-HSA-9006925
Host Interactions of HIV factors R-HSA-162909
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hh mutants are degraded by ERAD R-HSA-5362768
Cell Cycle R-HSA-1640170
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cytokine Signaling in Immune system R-HSA-1280215
p53-Independent DNA Damage Response R-HSA-69610
S Phase R-HSA-69242
Antigen processing-Cross presentation R-HSA-1236975
Asymmetric localization of PCP proteins R-HSA-4608870
Transcriptional regulation by RUNX3 R-HSA-8878159
Activation of NF-kappaB in B cells R-HSA-1169091
MAPK family signaling cascades R-HSA-5683057
PIP3 activates AKT signaling R-HSA-1257604
Mitotic G1 phase and G1/S transition R-HSA-453279
Separation of Sister Chromatids R-HSA-2467813
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic Anaphase R-HSA-68882
PTEN Regulation R-HSA-6807070
ABC-family proteins mediated transport R-HSA-382556
Metabolism of polyamines R-HSA-351202
ER-Phagosome pathway R-HSA-1236974
Mitotic G2-G2/M phases R-HSA-453274
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Immune System R-HSA-168256
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cyclin E associated events during G1/S transition R-HSA-69202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism of RNA R-HSA-8953854
Vif-mediated degradation of APOBEC3G R-HSA-180585
Infectious disease R-HSA-5663205
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Asparagine N-linked glycosylation R-HSA-446203
TCR signaling R-HSA-202403
Regulation of RUNX3 expression and activity R-HSA-8941858
Class I MHC mediated antigen processing & presentation R-HSA-983169
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by the B Cell Receptor (BCR) R-HSA-983705
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by Hedgehog R-HSA-5358351
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of Apoptosis R-HSA-169911
Cellular response to chemical stress R-HSA-9711123
Programmed Cell Death R-HSA-5357801
Metabolism of amino acids and derivatives R-HSA-71291
Transcriptional regulation by RUNX1 R-HSA-8878171
Downstream TCR signaling R-HSA-202424
G2/M Transition R-HSA-69275
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by NOTCH R-HSA-157118
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 signaling R-HSA-9020702
Post-translational protein modification R-HSA-597592
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Apoptosis R-HSA-109581
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
G1/S DNA Damage Checkpoints R-HSA-69615
HIV Infection R-HSA-162906
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Transport of small molecules R-HSA-382551
MAPK1/MAPK3 signaling R-HSA-5684996
Switching of origins to a post-replicative state R-HSA-69052
Metabolism of proteins R-HSA-392499
RAF/MAP kinase cascade R-HSA-5673001
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Assembly of the pre-replicative complex R-HSA-68867
RNA Polymerase II Transcription R-HSA-73857
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular response to hypoxia R-HSA-1234174
Nuclear events mediated by NFE2L2 R-HSA-9759194
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Hedgehog ligand biogenesis R-HSA-5358346
Ub-specific processing proteases R-HSA-5689880
G2/M Checkpoints R-HSA-69481
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Gene expression (Transcription) R-HSA-74160
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of mitotic cell cycle R-HSA-453276
Signaling by Interleukins R-HSA-449147
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cellular responses to stress R-HSA-2262752
G1/S Transition R-HSA-69206
Hedgehog 'off' state R-HSA-5610787
KEAP1-NFE2L2 pathway R-HSA-9755511
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cell Cycle, Mitotic R-HSA-69278
Innate Immune System R-HSA-168249
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX2 R-HSA-8878166
Synthesis of DNA R-HSA-69239
ABC transporter disorders R-HSA-5619084
Metabolism R-HSA-1430728
DNA Replication Pre-Initiation R-HSA-69002
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
UCH proteinases R-HSA-5689603
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
FCERI mediated NF-kB activation R-HSA-2871837
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX2 expression and activity R-HSA-8939902
Cell Cycle Checkpoints R-HSA-69620
Degradation of GLI1 by the proteasome R-HSA-5610780
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular response to hypoxia R-HSA-1234174
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RUNX2 expression and activity R-HSA-8939902
RNA Polymerase II Transcription R-HSA-73857
TCR signaling R-HSA-202403
Metabolism of proteins R-HSA-392499
G2/M Checkpoints R-HSA-69481
Signaling by Hedgehog R-HSA-5358351
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Vif-mediated degradation of APOBEC3G R-HSA-180585
ABC-family proteins mediated transport R-HSA-382556
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by ROBO receptors R-HSA-376176
Signaling by NOTCH4 R-HSA-9013694
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of DVL R-HSA-4641258
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX2 R-HSA-8878166
G1/S DNA Damage Checkpoints R-HSA-69615
Nervous system development R-HSA-9675108
Hedgehog 'off' state R-HSA-5610787
Negative regulation of NOTCH4 signaling R-HSA-9604323
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Switching of origins to a post-replicative state R-HSA-69052
Developmental Biology R-HSA-1266738
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cytokine Signaling in Immune system R-HSA-1280215
Disease R-HSA-1643685
Activation of NF-kappaB in B cells R-HSA-1169091
Assembly of the pre-replicative complex R-HSA-68867
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Synthesis of DNA R-HSA-69239
Asparagine N-linked glycosylation R-HSA-446203
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cell Cycle Checkpoints R-HSA-69620
Vpu mediated degradation of CD4 R-HSA-180534
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
Adaptive Immune System R-HSA-1280218
Stabilization of p53 R-HSA-69541
Metabolism of amino acids and derivatives R-HSA-71291
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Nuclear events mediated by NFE2L2 R-HSA-9759194
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by WNT R-HSA-195721
Generic Transcription Pathway R-HSA-212436
PCP/CE pathway R-HSA-4086400
ABC transporter disorders R-HSA-5619084
Programmed Cell Death R-HSA-5357801
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transport of small molecules R-HSA-382551
Downstream TCR signaling R-HSA-202424
Infectious disease R-HSA-5663205
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of RAS by GAPs R-HSA-5658442
Intracellular signaling by second messengers R-HSA-9006925
Regulation of PTEN stability and activity R-HSA-8948751
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Deubiquitination R-HSA-5688426
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Apoptosis R-HSA-109581
MAPK1/MAPK3 signaling R-HSA-5684996
Immune System R-HSA-168256
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Independent DNA Damage Response R-HSA-69610
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
M Phase R-HSA-68886
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
S Phase R-HSA-69242
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of RUNX3 expression and activity R-HSA-8941858
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by NOTCH R-HSA-157118
Cell Cycle, Mitotic R-HSA-69278
ER-Phagosome pathway R-HSA-1236974
Host Interactions of HIV factors R-HSA-162909
RAF/MAP kinase cascade R-HSA-5673001
Hh mutants are degraded by ERAD R-HSA-5362768
Separation of Sister Chromatids R-HSA-2467813
Neddylation R-HSA-8951664
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of Apoptosis R-HSA-169911
Interleukin-1 signaling R-HSA-9020702
Class I MHC mediated antigen processing & presentation R-HSA-983169
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic Metaphase and Anaphase R-HSA-2555396
DNA Replication R-HSA-69306
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle R-HSA-1640170
Axon guidance R-HSA-422475
Regulation of mitotic cell cycle R-HSA-453276
Beta-catenin independent WNT signaling R-HSA-3858494
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic Anaphase R-HSA-68882
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Ub-specific processing proteases R-HSA-5689880
Asymmetric localization of PCP proteins R-HSA-4608870
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
TCF dependent signaling in response to WNT R-HSA-201681
Innate Immune System R-HSA-168249
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism of RNA R-HSA-8953854
Hh mutants abrogate ligand secretion R-HSA-5387390
Defective CFTR causes cystic fibrosis R-HSA-5678895
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
HIV Infection R-HSA-162906
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Orc1 removal from chromatin R-HSA-68949
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK family signaling cascades R-HSA-5683057
Signaling by Interleukins R-HSA-449147
Post-translational protein modification R-HSA-597592
G2/M Transition R-HSA-69275
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cellular response to chemical stress R-HSA-9711123
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular responses to stress R-HSA-2262752
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism of polyamines R-HSA-351202
PTEN Regulation R-HSA-6807070
G1/S Transition R-HSA-69206
Degradation of GLI2 by the proteasome R-HSA-5610783
Hedgehog 'on' state R-HSA-5632684
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of AXIN R-HSA-4641257
UCH proteinases R-HSA-5689603
Disorders of transmembrane transporters R-HSA-5619115
Interleukin-1 family signaling R-HSA-446652
Cellular responses to stimuli R-HSA-8953897
Metabolism R-HSA-1430728
Antigen processing-Cross presentation R-HSA-1236975
Mitotic G2-G2/M phases R-HSA-453274
Mitotic G1 phase and G1/S transition R-HSA-453279
DNA Replication Pre-Initiation R-HSA-69002
MAPK6/MAPK4 signaling R-HSA-5687128
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
M Phase R-HSA-68886
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
DNA Replication R-HSA-69306
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Activation of NF-kappaB in B cells R-HSA-1169091
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hh mutants are degraded by ERAD R-HSA-5362768
Metabolism of RNA R-HSA-8953854
Signaling by NOTCH4 R-HSA-9013694
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Hedgehog R-HSA-5358351
MAPK6/MAPK4 signaling R-HSA-5687128
Innate Immune System R-HSA-168249
Vpu mediated degradation of CD4 R-HSA-180534
Deubiquitination R-HSA-5688426
Hedgehog 'off' state R-HSA-5610787
Vif-mediated degradation of APOBEC3G R-HSA-180585
PIP3 activates AKT signaling R-HSA-1257604
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX3 R-HSA-8878159
Disease R-HSA-1643685
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism R-HSA-1430728
S Phase R-HSA-69242
MAPK family signaling cascades R-HSA-5683057
Mitotic G1 phase and G1/S transition R-HSA-453279
Apoptosis R-HSA-109581
TCF dependent signaling in response to WNT R-HSA-201681
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of RUNX3 expression and activity R-HSA-8941858
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of AXIN R-HSA-4641257
Antigen processing-Cross presentation R-HSA-1236975
Adaptive Immune System R-HSA-1280218
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by ROBO receptors R-HSA-376176
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of DVL R-HSA-4641258
Cell Cycle, Mitotic R-HSA-69278
Signaling by NOTCH R-HSA-157118
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Downstream TCR signaling R-HSA-202424
Regulation of PTEN stability and activity R-HSA-8948751
Cellular responses to stress R-HSA-2262752
Assembly of the pre-replicative complex R-HSA-68867
Degradation of GLI1 by the proteasome R-HSA-5610780
Post-translational protein modification R-HSA-597592
Disorders of transmembrane transporters R-HSA-5619115
Cyclin E associated events during G1/S transition R-HSA-69202
Cytokine Signaling in Immune system R-HSA-1280215
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Dependent G1 DNA Damage Response R-HSA-69563
RAF/MAP kinase cascade R-HSA-5673001
RNA Polymerase II Transcription R-HSA-73857
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog ligand biogenesis R-HSA-5358346
Cellular response to hypoxia R-HSA-1234174
G1/S Transition R-HSA-69206
Hedgehog 'on' state R-HSA-5632684
Asparagine N-linked glycosylation R-HSA-446203
Signaling by WNT R-HSA-195721
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Transcriptional regulation by RUNX1 R-HSA-8878171
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
G2/M Checkpoints R-HSA-69481
FCERI mediated NF-kB activation R-HSA-2871837
PTEN Regulation R-HSA-6807070
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic Metaphase and Anaphase R-HSA-2555396
Developmental Biology R-HSA-1266738
Cell Cycle Checkpoints R-HSA-69620
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Independent DNA Damage Response R-HSA-69610
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by Interleukins R-HSA-449147
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism of proteins R-HSA-392499
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Transition R-HSA-69275
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
UCH proteinases R-HSA-5689603
G1/S DNA Damage Checkpoints R-HSA-69615
Axon guidance R-HSA-422475
Regulation of RAS by GAPs R-HSA-5658442
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Neddylation R-HSA-8951664
Defective CFTR causes cystic fibrosis R-HSA-5678895
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cell Cycle R-HSA-1640170
Immune System R-HSA-168256
ER-Phagosome pathway R-HSA-1236974
Interleukin-1 family signaling R-HSA-446652
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Generic Transcription Pathway R-HSA-212436
C-type lectin receptors (CLRs) R-HSA-5621481
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism of polyamines R-HSA-351202
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PCP/CE pathway R-HSA-4086400
Infectious disease R-HSA-5663205
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nervous system development R-HSA-9675108
Host Interactions of HIV factors R-HSA-162909
Nuclear events mediated by NFE2L2 R-HSA-9759194
Mitotic G2-G2/M phases R-HSA-453274
HIV Infection R-HSA-162906
Regulation of Apoptosis R-HSA-169911
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
Signal Transduction R-HSA-162582
ABC-family proteins mediated transport R-HSA-382556
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of mitotic cell cycle R-HSA-453276
Ub-specific processing proteases R-HSA-5689880
Asymmetric localization of PCP proteins R-HSA-4608870
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TCR signaling R-HSA-202403
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular responses to stimuli R-HSA-8953897
DNA Replication Pre-Initiation R-HSA-69002
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Synthesis of DNA R-HSA-69239
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
KEAP1-NFE2L2 pathway R-HSA-9755511
Separation of Sister Chromatids R-HSA-2467813
Stabilization of p53 R-HSA-69541
Orc1 removal from chromatin R-HSA-68949
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of beta-catenin by the destruction complex R-HSA-195253
Gene expression (Transcription) R-HSA-74160
Transport of small molecules R-HSA-382551
Mitotic Anaphase R-HSA-68882
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Interleukin-1 signaling R-HSA-9020702
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114

Expression Atlas ENSG00000100764
NCBI gene (formerly Entrezgene) 5700
GeneCards 9547
HGNC Symbol HGNC:9547
MIM gene 602706
MIM morbid 620071
UniProtKB Gene Name Q53XL8
WikiGene 5700
Gene: PSMB8
Ensembl ID : ENSG00000204264
Description: proteasome 20S subunit beta 8
Gene Synonyms: BETA5I,D6S216E,LMP7,PSMB5I,RING10
6 APIs:
221 Possible Orthologues:

Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Synthesis of DNA R-HSA-69239
Ub-specific processing proteases R-HSA-5689880
ABC transporter disorders R-HSA-5619084
Post-translational protein modification R-HSA-597592
ABC-family proteins mediated transport R-HSA-382556
Programmed Cell Death R-HSA-5357801
FCERI mediated NF-kB activation R-HSA-2871837
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Nervous system development R-HSA-9675108
Switching of origins to a post-replicative state R-HSA-69052
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of beta-catenin by the destruction complex R-HSA-195253
Gene expression (Transcription) R-HSA-74160
G2/M Transition R-HSA-69275
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
KEAP1-NFE2L2 pathway R-HSA-9755511
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Interleukin-1 family signaling R-HSA-446652
Regulation of Apoptosis R-HSA-169911
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
MAPK family signaling cascades R-HSA-5683057
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Metabolism of amino acids and derivatives R-HSA-71291
MAPK1/MAPK3 signaling R-HSA-5684996
S Phase R-HSA-69242
Vif-mediated degradation of APOBEC3G R-HSA-180585
Hedgehog ligand biogenesis R-HSA-5358346
Developmental Biology R-HSA-1266738
Orc1 removal from chromatin R-HSA-68949
Stabilization of p53 R-HSA-69541
Metabolism R-HSA-1430728
Hedgehog 'on' state R-HSA-5632684
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by NOTCH4 R-HSA-9013694
Cell Cycle R-HSA-1640170
Cytokine Signaling in Immune system R-HSA-1280215
PTEN Regulation R-HSA-6807070
RAF/MAP kinase cascade R-HSA-5673001
HIV Infection R-HSA-162906
TCF dependent signaling in response to WNT R-HSA-201681
Interleukin-1 signaling R-HSA-9020702
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX3 R-HSA-8878159
G1/S DNA Damage Checkpoints R-HSA-69615
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cellular response to chemical stress R-HSA-9711123
Regulation of RAS by GAPs R-HSA-5658442
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of GLI1 by the proteasome R-HSA-5610780
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by WNT R-HSA-195721
C-type lectin receptors (CLRs) R-HSA-5621481
Mitotic Metaphase and Anaphase R-HSA-2555396
CLEC7A (Dectin-1) signaling R-HSA-5607764
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH R-HSA-157118
Immune System R-HSA-168256
Beta-catenin independent WNT signaling R-HSA-3858494
G1/S Transition R-HSA-69206
Degradation of DVL R-HSA-4641258
Metabolism of proteins R-HSA-392499
Mitotic G1 phase and G1/S transition R-HSA-453279
ER-Phagosome pathway R-HSA-1236974
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Intracellular signaling by second messengers R-HSA-9006925
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of mitotic cell cycle R-HSA-453276
Transcriptional regulation by RUNX2 R-HSA-8878166
Infectious disease R-HSA-5663205
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing-Cross presentation R-HSA-1236975
Signaling by Interleukins R-HSA-449147
Interferon alpha/beta signaling R-HSA-909733
PIP3 activates AKT signaling R-HSA-1257604
UCH proteinases R-HSA-5689603
Cell Cycle Checkpoints R-HSA-69620
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Disorders of transmembrane transporters R-HSA-5619115
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
Axon guidance R-HSA-422475
Apoptosis R-HSA-109581
Vpu mediated degradation of CD4 R-HSA-180534
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of polyamines R-HSA-351202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cell Cycle, Mitotic R-HSA-69278
Signal Transduction R-HSA-162582
Negative regulation of NOTCH4 signaling R-HSA-9604323
Neddylation R-HSA-8951664
DNA Replication R-HSA-69306
TCR signaling R-HSA-202403
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
p53-Independent DNA Damage Response R-HSA-69610
Interferon Signaling R-HSA-913531
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular responses to stimuli R-HSA-8953897
Signaling by Hedgehog R-HSA-5358351
Metabolism of RNA R-HSA-8953854
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Host Interactions of HIV factors R-HSA-162909
Separation of Sister Chromatids R-HSA-2467813
Adaptive Immune System R-HSA-1280218
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX2 expression and activity R-HSA-8939902
PCP/CE pathway R-HSA-4086400
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Transport of small molecules R-HSA-382551
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Assembly of the pre-replicative complex R-HSA-68867
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Mitotic G2-G2/M phases R-HSA-453274
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Defective CFTR causes cystic fibrosis R-HSA-5678895
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Innate Immune System R-HSA-168249
Deubiquitination R-HSA-5688426
Disease R-HSA-1643685
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of PTEN stability and activity R-HSA-8948751
M Phase R-HSA-68886
Degradation of AXIN R-HSA-4641257
Signaling by ROBO receptors R-HSA-376176
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic Anaphase R-HSA-68882
Downstream TCR signaling R-HSA-202424
Hh mutants abrogate ligand secretion R-HSA-5387390
DNA Replication Pre-Initiation R-HSA-69002
Regulation of RUNX3 expression and activity R-HSA-8941858
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Transcriptional regulation by RUNX1 R-HSA-8878171
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Nervous system development R-HSA-9675108
M Phase R-HSA-68886
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Metabolism R-HSA-1430728
Interleukin-1 signaling R-HSA-9020702
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of GLI1 by the proteasome R-HSA-5610780
Signal Transduction R-HSA-162582
Cellular responses to stress R-HSA-2262752
Cyclin E associated events during G1/S transition R-HSA-69202
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Apoptosis R-HSA-109581
Post-translational protein modification R-HSA-597592
Metabolism of RNA R-HSA-8953854
Vpu mediated degradation of CD4 R-HSA-180534
Neddylation R-HSA-8951664
Metabolism of amino acids and derivatives R-HSA-71291
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular response to chemical stress R-HSA-9711123
Mitotic G2-G2/M phases R-HSA-453274
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mitotic cell cycle R-HSA-453276
Signaling by Hedgehog R-HSA-5358351
G2/M Transition R-HSA-69275
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hedgehog ligand biogenesis R-HSA-5358346
Interferon Signaling R-HSA-913531
Generic Transcription Pathway R-HSA-212436
Interferon alpha/beta signaling R-HSA-909733
Stabilization of p53 R-HSA-69541
Orc1 removal from chromatin R-HSA-68949
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Asymmetric localization of PCP proteins R-HSA-4608870
HIV Infection R-HSA-162906
Signaling by WNT R-HSA-195721
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by NOTCH4 R-HSA-9013694
ABC-family proteins mediated transport R-HSA-382556
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic Anaphase R-HSA-68882
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Host Interactions of HIV factors R-HSA-162909
Metabolism of polyamines R-HSA-351202
Regulation of PTEN stability and activity R-HSA-8948751
S Phase R-HSA-69242
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by Interleukins R-HSA-449147
Class I MHC mediated antigen processing & presentation R-HSA-983169
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by ROBO receptors R-HSA-376176
Intracellular signaling by second messengers R-HSA-9006925
Degradation of GLI2 by the proteasome R-HSA-5610783
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of Apoptosis R-HSA-169911
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
FCERI mediated NF-kB activation R-HSA-2871837
Assembly of the pre-replicative complex R-HSA-68867
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK1/MAPK3 signaling R-HSA-5684996
Developmental Biology R-HSA-1266738
Regulation of RUNX2 expression and activity R-HSA-8939902
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
TCR signaling R-HSA-202403
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Disease R-HSA-1643685
TCF dependent signaling in response to WNT R-HSA-201681
PIP3 activates AKT signaling R-HSA-1257604
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Disorders of transmembrane transporters R-HSA-5619115
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
UCH proteinases R-HSA-5689603
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
RAF/MAP kinase cascade R-HSA-5673001
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hedgehog 'on' state R-HSA-5632684
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G2/M Checkpoints R-HSA-69481
Degradation of beta-catenin by the destruction complex R-HSA-195253
G1/S Transition R-HSA-69206
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Deubiquitination R-HSA-5688426
Infectious disease R-HSA-5663205
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
CLEC7A (Dectin-1) signaling R-HSA-5607764
DNA Replication R-HSA-69306
Degradation of AXIN R-HSA-4641257
Regulation of RUNX3 expression and activity R-HSA-8941858
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by NOTCH R-HSA-157118
Separation of Sister Chromatids R-HSA-2467813
p53-Independent DNA Damage Response R-HSA-69610
Ub-specific processing proteases R-HSA-5689880
Degradation of DVL R-HSA-4641258
Axon guidance R-HSA-422475
Cellular response to hypoxia R-HSA-1234174
PCP/CE pathway R-HSA-4086400
Hh mutants are degraded by ERAD R-HSA-5362768
C-type lectin receptors (CLRs) R-HSA-5621481
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Synthesis of DNA R-HSA-69239
PTEN Regulation R-HSA-6807070
RNA Polymerase II Transcription R-HSA-73857
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Antigen processing-Cross presentation R-HSA-1236975
Innate Immune System R-HSA-168249
Cellular responses to stimuli R-HSA-8953897
Regulation of RAS by GAPs R-HSA-5658442
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
ABC transporter disorders R-HSA-5619084
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Metaphase and Anaphase R-HSA-2555396
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 family signaling R-HSA-446652
Programmed Cell Death R-HSA-5357801
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Nuclear events mediated by NFE2L2 R-HSA-9759194
ER-Phagosome pathway R-HSA-1236974
p53-Dependent G1 DNA Damage Response R-HSA-69563
Immune System R-HSA-168256
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Gene expression (Transcription) R-HSA-74160
MAPK family signaling cascades R-HSA-5683057
Transport of small molecules R-HSA-382551
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hedgehog 'off' state R-HSA-5610787
Beta-catenin independent WNT signaling R-HSA-3858494
Cytokine Signaling in Immune system R-HSA-1280215
Adaptive Immune System R-HSA-1280218
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX3 R-HSA-8878159
Cell Cycle, Mitotic R-HSA-69278
DNA Replication Pre-Initiation R-HSA-69002
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of proteins R-HSA-392499
Switching of origins to a post-replicative state R-HSA-69052
Downstream TCR signaling R-HSA-202424
Activation of NF-kappaB in B cells R-HSA-1169091
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Hh mutants are degraded by ERAD R-HSA-5362768
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Gene expression (Transcription) R-HSA-74160
Apoptosis R-HSA-109581
Regulation of RUNX2 expression and activity R-HSA-8939902
DNA Replication R-HSA-69306
Signaling by NOTCH4 R-HSA-9013694
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
PIP3 activates AKT signaling R-HSA-1257604
G2/M Transition R-HSA-69275
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Disorders of transmembrane transporters R-HSA-5619115
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Ub-specific processing proteases R-HSA-5689880
Regulation of Apoptosis R-HSA-169911
UCH proteinases R-HSA-5689603
Transport of small molecules R-HSA-382551
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Synthesis of DNA R-HSA-69239
Activation of NF-kappaB in B cells R-HSA-1169091
Assembly of the pre-replicative complex R-HSA-68867
Infectious disease R-HSA-5663205
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Host Interactions of HIV factors R-HSA-162909
ABC transporter disorders R-HSA-5619084
Interferon alpha/beta signaling R-HSA-909733
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Orc1 removal from chromatin R-HSA-68949
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Interleukins R-HSA-449147
Generic Transcription Pathway R-HSA-212436
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of GLI2 by the proteasome R-HSA-5610783
Innate Immune System R-HSA-168249
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interferon Signaling R-HSA-913531
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic Anaphase R-HSA-68882
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular responses to stimuli R-HSA-8953897
Metabolism of proteins R-HSA-392499
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of NOTCH4 signaling R-HSA-9604323
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
DNA Replication Pre-Initiation R-HSA-69002
G1/S Transition R-HSA-69206
Developmental Biology R-HSA-1266738
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by ROBO receptors R-HSA-376176
S Phase R-HSA-69242
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX2 R-HSA-8878166
FCERI mediated NF-kB activation R-HSA-2871837
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Deubiquitination R-HSA-5688426
p53-Independent DNA Damage Response R-HSA-69610
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX3 R-HSA-8878159
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of GLI1 by the proteasome R-HSA-5610780
G2/M Checkpoints R-HSA-69481
ABC-family proteins mediated transport R-HSA-382556
Degradation of AXIN R-HSA-4641257
Neddylation R-HSA-8951664
Mitotic G1 phase and G1/S transition R-HSA-453279
TCR signaling R-HSA-202403
Hedgehog 'on' state R-HSA-5632684
ER-Phagosome pathway R-HSA-1236974
MAPK family signaling cascades R-HSA-5683057
TCF dependent signaling in response to WNT R-HSA-201681
Switching of origins to a post-replicative state R-HSA-69052
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular response to hypoxia R-HSA-1234174
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cell Cycle R-HSA-1640170
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular responses to stress R-HSA-2262752
Axon guidance R-HSA-422475
Metabolism of polyamines R-HSA-351202
Stabilization of p53 R-HSA-69541
Degradation of beta-catenin by the destruction complex R-HSA-195253
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of amino acids and derivatives R-HSA-71291
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by WNT R-HSA-195721
Interleukin-1 family signaling R-HSA-446652
Cell Cycle, Mitotic R-HSA-69278
Nervous system development R-HSA-9675108
Mitotic Metaphase and Anaphase R-HSA-2555396
Hedgehog ligand biogenesis R-HSA-5358346
Immune System R-HSA-168256
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PTEN Regulation R-HSA-6807070
M Phase R-HSA-68886
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle Checkpoints R-HSA-69620
Degradation of DVL R-HSA-4641258
Mitotic G2-G2/M phases R-HSA-453274
Interleukin-1 signaling R-HSA-9020702
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RAS by GAPs R-HSA-5658442
Programmed Cell Death R-HSA-5357801
Cyclin E associated events during G1/S transition R-HSA-69202
MAPK6/MAPK4 signaling R-HSA-5687128
Metabolism R-HSA-1430728
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by NOTCH R-HSA-157118
Post-translational protein modification R-HSA-597592
Downstream TCR signaling R-HSA-202424
Regulation of expression of SLITs and ROBOs R-HSA-9010553
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PCP/CE pathway R-HSA-4086400
MAPK1/MAPK3 signaling R-HSA-5684996
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of mitotic cell cycle R-HSA-453276
Signal Transduction R-HSA-162582
RNA Polymerase II Transcription R-HSA-73857
HIV Infection R-HSA-162906
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cellular response to chemical stress R-HSA-9711123
Hedgehog 'off' state R-HSA-5610787
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Antigen processing-Cross presentation R-HSA-1236975
Regulation of PTEN stability and activity R-HSA-8948751
Nuclear events mediated by NFE2L2 R-HSA-9759194
Adaptive Immune System R-HSA-1280218
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of RNA R-HSA-8953854
Defective CFTR causes cystic fibrosis R-HSA-5678895
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disease R-HSA-1643685
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of RUNX3 expression and activity R-HSA-8941858
C-type lectin receptors (CLRs) R-HSA-5621481
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by Hedgehog R-HSA-5358351
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
ER-Phagosome pathway R-HSA-1236974
Regulation of mitotic cell cycle R-HSA-453276
HIV Infection R-HSA-162906
Hedgehog ligand biogenesis R-HSA-5358346
Interferon alpha/beta signaling R-HSA-909733
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of RUNX3 expression and activity R-HSA-8941858
G2/M Transition R-HSA-69275
MAPK6/MAPK4 signaling R-HSA-5687128
Antigen processing-Cross presentation R-HSA-1236975
G1/S Transition R-HSA-69206
DNA Replication R-HSA-69306
KEAP1-NFE2L2 pathway R-HSA-9755511
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Disorders of transmembrane transporters R-HSA-5619115
G1/S DNA Damage Checkpoints R-HSA-69615
Cellular response to chemical stress R-HSA-9711123
Cell Cycle Checkpoints R-HSA-69620
Generic Transcription Pathway R-HSA-212436
Regulation of Apoptosis R-HSA-169911
Orc1 removal from chromatin R-HSA-68949
Signaling by Interleukins R-HSA-449147
Metabolism R-HSA-1430728
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Vpu mediated degradation of CD4 R-HSA-180534
Cell Cycle, Mitotic R-HSA-69278
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Host Interactions of HIV factors R-HSA-162909
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
M Phase R-HSA-68886
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TCF dependent signaling in response to WNT R-HSA-201681
Synthesis of DNA R-HSA-69239
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Deubiquitination R-HSA-5688426
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
PCP/CE pathway R-HSA-4086400
Mitotic Anaphase R-HSA-68882
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Axon guidance R-HSA-422475
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transcriptional regulation by RUNX1 R-HSA-8878171
Class I MHC mediated antigen processing & presentation R-HSA-983169
Disease R-HSA-1643685
Nervous system development R-HSA-9675108
Hedgehog 'on' state R-HSA-5632684
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
FCERI mediated NF-kB activation R-HSA-2871837
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of RNA R-HSA-8953854
Signaling by NOTCH R-HSA-157118
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Mitotic G1 phase and G1/S transition R-HSA-453279
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
p53-Dependent G1 DNA Damage Response R-HSA-69563
RAF/MAP kinase cascade R-HSA-5673001
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Interleukin-1 signaling R-HSA-9020702
Switching of origins to a post-replicative state R-HSA-69052
Infectious disease R-HSA-5663205
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Neddylation R-HSA-8951664
Mitotic G2-G2/M phases R-HSA-453274
Post-translational protein modification R-HSA-597592
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PTEN Regulation R-HSA-6807070
Signaling by NOTCH4 R-HSA-9013694
Metabolism of amino acids and derivatives R-HSA-71291
Gene expression (Transcription) R-HSA-74160
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX2 R-HSA-8878166
Developmental Biology R-HSA-1266738
MAPK family signaling cascades R-HSA-5683057
Degradation of DVL R-HSA-4641258
Metabolism of proteins R-HSA-392499
Ub-specific processing proteases R-HSA-5689880
Separation of Sister Chromatids R-HSA-2467813
Cellular responses to stress R-HSA-2262752
Degradation of GLI2 by the proteasome R-HSA-5610783
Interleukin-1 family signaling R-HSA-446652
RNA Polymerase II Transcription R-HSA-73857
TCR signaling R-HSA-202403
Metabolism of polyamines R-HSA-351202
Programmed Cell Death R-HSA-5357801
Cellular response to hypoxia R-HSA-1234174
Apoptosis R-HSA-109581
Defective CFTR causes cystic fibrosis R-HSA-5678895
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of PTEN stability and activity R-HSA-8948751
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Hh mutants abrogate ligand secretion R-HSA-5387390
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
CLEC7A (Dectin-1) signaling R-HSA-5607764
DNA Replication Pre-Initiation R-HSA-69002
ABC transporter disorders R-HSA-5619084
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog 'off' state R-HSA-5610787
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interferon Signaling R-HSA-913531
Assembly of the pre-replicative complex R-HSA-68867
Degradation of AXIN R-HSA-4641257
Downstream TCR signaling R-HSA-202424
C-type lectin receptors (CLRs) R-HSA-5621481
Stabilization of p53 R-HSA-69541
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of beta-catenin by the destruction complex R-HSA-195253
Asymmetric localization of PCP proteins R-HSA-4608870
ABC-family proteins mediated transport R-HSA-382556
Immune System R-HSA-168256
Cellular responses to stimuli R-HSA-8953897
Adaptive Immune System R-HSA-1280218
Degradation of GLI1 by the proteasome R-HSA-5610780
Transport of small molecules R-HSA-382551
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of RAS by GAPs R-HSA-5658442
Signaling by ROBO receptors R-HSA-376176
Cytokine Signaling in Immune system R-HSA-1280215
UCH proteinases R-HSA-5689603
Negative regulation of NOTCH4 signaling R-HSA-9604323
S Phase R-HSA-69242
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by WNT R-HSA-195721
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Innate Immune System R-HSA-168249
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transcriptional regulation by RUNX3 R-HSA-8878159
G2/M Checkpoints R-HSA-69481
Disorders of transmembrane transporters R-HSA-5619115
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Separation of Sister Chromatids R-HSA-2467813
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of polyamines R-HSA-351202
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Infectious disease R-HSA-5663205
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hh mutants are degraded by ERAD R-HSA-5362768
DNA Replication Pre-Initiation R-HSA-69002
Cytokine Signaling in Immune system R-HSA-1280215
MAPK6/MAPK4 signaling R-HSA-5687128
Interferon alpha/beta signaling R-HSA-909733
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Orc1 removal from chromatin R-HSA-68949
Mitotic Metaphase and Anaphase R-HSA-2555396
Transcriptional regulation by RUNX3 R-HSA-8878159
Post-translational protein modification R-HSA-597592
DNA Replication R-HSA-69306
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Disease R-HSA-1643685
Regulation of RUNX2 expression and activity R-HSA-8939902
G1/S Transition R-HSA-69206
Mitotic Anaphase R-HSA-68882
NIK-->noncanonical NF-kB signaling R-HSA-5676590
RAF/MAP kinase cascade R-HSA-5673001
Ub-specific processing proteases R-HSA-5689880
Regulation of RAS by GAPs R-HSA-5658442
Asymmetric localization of PCP proteins R-HSA-4608870
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Assembly of the pre-replicative complex R-HSA-68867
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
S Phase R-HSA-69242
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
UCH proteinases R-HSA-5689603
CLEC7A (Dectin-1) signaling R-HSA-5607764
Stabilization of p53 R-HSA-69541
Transport of small molecules R-HSA-382551
Metabolism of RNA R-HSA-8953854
C-type lectin receptors (CLRs) R-HSA-5621481
Cellular response to chemical stress R-HSA-9711123
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
PTEN Regulation R-HSA-6807070
Signaling by WNT R-HSA-195721
Regulation of PTEN stability and activity R-HSA-8948751
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by NOTCH R-HSA-157118
Defective CFTR causes cystic fibrosis R-HSA-5678895
ABC-family proteins mediated transport R-HSA-382556
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
HIV Infection R-HSA-162906
Programmed Cell Death R-HSA-5357801
Metabolism of proteins R-HSA-392499
Class I MHC mediated antigen processing & presentation R-HSA-983169
PIP3 activates AKT signaling R-HSA-1257604
Axon guidance R-HSA-422475
Regulation of RUNX3 expression and activity R-HSA-8941858
Generic Transcription Pathway R-HSA-212436
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Signaling by Interleukins R-HSA-449147
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog 'off' state R-HSA-5610787
Metabolism R-HSA-1430728
ABC transporter disorders R-HSA-5619084
Cellular responses to stress R-HSA-2262752
Nuclear events mediated by NFE2L2 R-HSA-9759194
ER-Phagosome pathway R-HSA-1236974
TCR signaling R-HSA-202403
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle R-HSA-1640170
Immune System R-HSA-168256
Adaptive Immune System R-HSA-1280218
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
MAPK family signaling cascades R-HSA-5683057
p53-Dependent G1 DNA Damage Response R-HSA-69563
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of amino acids and derivatives R-HSA-71291
p53-Independent DNA Damage Response R-HSA-69610
Host Interactions of HIV factors R-HSA-162909
Vif-mediated degradation of APOBEC3G R-HSA-180585
Downstream TCR signaling R-HSA-202424
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog 'on' state R-HSA-5632684
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Synthesis of DNA R-HSA-69239
Signaling by NOTCH4 R-HSA-9013694
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hedgehog ligand biogenesis R-HSA-5358346
Cell Cycle, Mitotic R-HSA-69278
Regulation of Apoptosis R-HSA-169911
G1/S DNA Damage Checkpoints R-HSA-69615
Intracellular signaling by second messengers R-HSA-9006925
M Phase R-HSA-68886
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by ROBO receptors R-HSA-376176
Switching of origins to a post-replicative state R-HSA-69052
MAPK1/MAPK3 signaling R-HSA-5684996
Innate Immune System R-HSA-168249
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX1 R-HSA-8878171
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular responses to stimuli R-HSA-8953897
Interleukin-1 signaling R-HSA-9020702
Negative regulation of NOTCH4 signaling R-HSA-9604323
KEAP1-NFE2L2 pathway R-HSA-9755511
Interleukin-1 family signaling R-HSA-446652
PCP/CE pathway R-HSA-4086400
Transcriptional regulation by RUNX2 R-HSA-8878166
Nervous system development R-HSA-9675108
Interferon Signaling R-HSA-913531
Degradation of GLI1 by the proteasome R-HSA-5610780
Mitotic G1 phase and G1/S transition R-HSA-453279
Apoptosis R-HSA-109581
Beta-catenin independent WNT signaling R-HSA-3858494
Cyclin E associated events during G1/S transition R-HSA-69202
Neddylation R-HSA-8951664
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Mitotic G2-G2/M phases R-HSA-453274
Developmental Biology R-HSA-1266738
Degradation of GLI2 by the proteasome R-HSA-5610783
Signal Transduction R-HSA-162582
Cell Cycle Checkpoints R-HSA-69620
Deubiquitination R-HSA-5688426
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of AXIN R-HSA-4641257
Cellular response to hypoxia R-HSA-1234174
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G2/M Transition R-HSA-69275
G2/M Checkpoints R-HSA-69481
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of DVL R-HSA-4641258
Vpu mediated degradation of CD4 R-HSA-180534
Antigen processing-Cross presentation R-HSA-1236975
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Interleukin-1 signaling R-HSA-9020702
Transcriptional regulation by RUNX2 R-HSA-8878166
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G2/M Checkpoints R-HSA-69481
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of RAS by GAPs R-HSA-5658442
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RUNX3 expression and activity R-HSA-8941858
Programmed Cell Death R-HSA-5357801
Innate Immune System R-HSA-168249
Mitotic Anaphase R-HSA-68882
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH R-HSA-157118
Apoptosis R-HSA-109581
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Generic Transcription Pathway R-HSA-212436
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Orc1 removal from chromatin R-HSA-68949
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Host Interactions of HIV factors R-HSA-162909
Gene expression (Transcription) R-HSA-74160
Mitotic G2-G2/M phases R-HSA-453274
Immune System R-HSA-168256
Signaling by WNT R-HSA-195721
Infectious disease R-HSA-5663205
Degradation of DVL R-HSA-4641258
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Neddylation R-HSA-8951664
Assembly of the pre-replicative complex R-HSA-68867
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of AXIN R-HSA-4641257
Interferon Signaling R-HSA-913531
Activation of NF-kappaB in B cells R-HSA-1169091
Antigen processing-Cross presentation R-HSA-1236975
Interferon alpha/beta signaling R-HSA-909733
Signaling by Hedgehog R-HSA-5358351
Switching of origins to a post-replicative state R-HSA-69052
Disorders of transmembrane transporters R-HSA-5619115
G2/M Transition R-HSA-69275
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of mitotic cell cycle R-HSA-453276
RAF/MAP kinase cascade R-HSA-5673001
C-type lectin receptors (CLRs) R-HSA-5621481
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Adaptive Immune System R-HSA-1280218
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stimuli R-HSA-8953897
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of GLI2 by the proteasome R-HSA-5610783
Vpu mediated degradation of CD4 R-HSA-180534
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of Apoptosis R-HSA-169911
Developmental Biology R-HSA-1266738
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cell Cycle R-HSA-1640170
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Nervous system development R-HSA-9675108
Cellular responses to stress R-HSA-2262752
PCP/CE pathway R-HSA-4086400
Cytokine Signaling in Immune system R-HSA-1280215
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Axon guidance R-HSA-422475
M Phase R-HSA-68886
Degradation of beta-catenin by the destruction complex R-HSA-195253
Defective CFTR causes cystic fibrosis R-HSA-5678895
ER-Phagosome pathway R-HSA-1236974
Metabolism R-HSA-1430728
Metabolism of polyamines R-HSA-351202
Signaling by ROBO receptors R-HSA-376176
G1/S DNA Damage Checkpoints R-HSA-69615
Synthesis of DNA R-HSA-69239
TCR signaling R-HSA-202403
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular response to hypoxia R-HSA-1234174
Intracellular signaling by second messengers R-HSA-9006925
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cell Cycle Checkpoints R-HSA-69620
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication R-HSA-69306
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
MAPK1/MAPK3 signaling R-HSA-5684996
Post-translational protein modification R-HSA-597592
Regulation of RUNX2 expression and activity R-HSA-8939902
Asymmetric localization of PCP proteins R-HSA-4608870
Separation of Sister Chromatids R-HSA-2467813
ABC transporter disorders R-HSA-5619084
G1/S Transition R-HSA-69206
Metabolism of proteins R-HSA-392499
Hh mutants are degraded by ERAD R-HSA-5362768
DNA Replication Pre-Initiation R-HSA-69002
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
RNA Polymerase II Transcription R-HSA-73857
Signaling by Interleukins R-HSA-449147
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX3 R-HSA-8878159
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transport of small molecules R-HSA-382551
Downstream TCR signaling R-HSA-202424
PTEN Regulation R-HSA-6807070
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of PTEN stability and activity R-HSA-8948751
HIV Infection R-HSA-162906
p53-Dependent G1 DNA Damage Response R-HSA-69563
p53-Independent DNA Damage Response R-HSA-69610
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of RNA R-HSA-8953854
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog 'on' state R-HSA-5632684
Signaling by NOTCH4 R-HSA-9013694
PIP3 activates AKT signaling R-HSA-1257604
Deubiquitination R-HSA-5688426
Hedgehog ligand biogenesis R-HSA-5358346
S Phase R-HSA-69242
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
MAPK family signaling cascades R-HSA-5683057
TCF dependent signaling in response to WNT R-HSA-201681
UCH proteinases R-HSA-5689603
Interleukin-1 family signaling R-HSA-446652
Mitotic G1 phase and G1/S transition R-HSA-453279
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cellular response to chemical stress R-HSA-9711123
Hedgehog 'off' state R-HSA-5610787
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
ABC-family proteins mediated transport R-HSA-382556
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cell Cycle, Mitotic R-HSA-69278
Beta-catenin independent WNT signaling R-HSA-3858494
FCERI mediated NF-kB activation R-HSA-2871837
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Class I MHC mediated antigen processing & presentation R-HSA-983169
Ub-specific processing proteases R-HSA-5689880
Mitotic Metaphase and Anaphase R-HSA-2555396
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Stabilization of p53 R-HSA-69541
Interferon Signaling R-HSA-913531
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of AXIN R-HSA-4641257
M Phase R-HSA-68886
Negative regulation of NOTCH4 signaling R-HSA-9604323
Disease R-HSA-1643685
Mitotic Anaphase R-HSA-68882
Signaling by ROBO receptors R-HSA-376176
Transcriptional regulation by RUNX3 R-HSA-8878159
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCR signaling R-HSA-202403
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Interferon alpha/beta signaling R-HSA-909733
PTEN Regulation R-HSA-6807070
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
C-type lectin receptors (CLRs) R-HSA-5621481
G1/S Transition R-HSA-69206
Stabilization of p53 R-HSA-69541
Hh mutants abrogate ligand secretion R-HSA-5387390
Immune System R-HSA-168256
Signaling by Hedgehog R-HSA-5358351
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Generic Transcription Pathway R-HSA-212436
Interleukin-1 signaling R-HSA-9020702
Infectious disease R-HSA-5663205
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle Checkpoints R-HSA-69620
Signaling by Interleukins R-HSA-449147
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Checkpoints R-HSA-69481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Deubiquitination R-HSA-5688426
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of expression of SLITs and ROBOs R-HSA-9010553
HIV Infection R-HSA-162906
Axon guidance R-HSA-422475
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cellular response to hypoxia R-HSA-1234174
DNA Replication Pre-Initiation R-HSA-69002
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cell Cycle, Mitotic R-HSA-69278
Cellular response to chemical stress R-HSA-9711123
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Assembly of the pre-replicative complex R-HSA-68867
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Vpu mediated degradation of CD4 R-HSA-180534
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of DVL R-HSA-4641258
Regulation of Apoptosis R-HSA-169911
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Developmental Biology R-HSA-1266738
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Asymmetric localization of PCP proteins R-HSA-4608870
PCP/CE pathway R-HSA-4086400
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK1/MAPK3 signaling R-HSA-5684996
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic G1 phase and G1/S transition R-HSA-453279
Switching of origins to a post-replicative state R-HSA-69052
Neddylation R-HSA-8951664
Hedgehog 'on' state R-HSA-5632684
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream TCR signaling R-HSA-202424
Synthesis of DNA R-HSA-69239
Cyclin E associated events during G1/S transition R-HSA-69202
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
G1/S DNA Damage Checkpoints R-HSA-69615
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Separation of Sister Chromatids R-HSA-2467813
Cell Cycle R-HSA-1640170
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by NOTCH4 R-HSA-9013694
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of GLI2 by the proteasome R-HSA-5610783
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of mitotic cell cycle R-HSA-453276
Disorders of transmembrane transporters R-HSA-5619115
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
KEAP1-NFE2L2 pathway R-HSA-9755511
Intracellular signaling by second messengers R-HSA-9006925
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
DNA Replication R-HSA-69306
MAPK family signaling cascades R-HSA-5683057
Signaling by NOTCH R-HSA-157118
Regulation of PTEN stability and activity R-HSA-8948751
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
G2/M Transition R-HSA-69275
Interleukin-1 family signaling R-HSA-446652
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
NIK-->noncanonical NF-kB signaling R-HSA-5676590
ABC transporter disorders R-HSA-5619084
Host Interactions of HIV factors R-HSA-162909
Cellular responses to stress R-HSA-2262752
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Apoptosis R-HSA-109581
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cytokine Signaling in Immune system R-HSA-1280215
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PIP3 activates AKT signaling R-HSA-1257604
Class I MHC mediated antigen processing & presentation R-HSA-983169
Transport of small molecules R-HSA-382551
Metabolism of proteins R-HSA-392499
p53-Independent DNA Damage Response R-HSA-69610
S Phase R-HSA-69242
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
UCH proteinases R-HSA-5689603
ER-Phagosome pathway R-HSA-1236974
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism of polyamines R-HSA-351202
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of RAS by GAPs R-HSA-5658442
TCF dependent signaling in response to WNT R-HSA-201681
Transcriptional regulation by RUNX2 R-HSA-8878166
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by WNT R-HSA-195721
Degradation of beta-catenin by the destruction complex R-HSA-195253
Nervous system development R-HSA-9675108
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Activation of NF-kappaB in B cells R-HSA-1169091
Post-translational protein modification R-HSA-597592
Cellular responses to stimuli R-HSA-8953897
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog 'off' state R-HSA-5610787
Beta-catenin independent WNT signaling R-HSA-3858494
Programmed Cell Death R-HSA-5357801
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of RNA R-HSA-8953854
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Metabolism R-HSA-1430728
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Ub-specific processing proteases R-HSA-5689880
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Checkpoints R-HSA-69481
Infectious disease R-HSA-5663205
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of proteins R-HSA-392499
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Mitotic Metaphase and Anaphase R-HSA-2555396
Stabilization of p53 R-HSA-69541
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of RUNX2 expression and activity R-HSA-8939902
Asymmetric localization of PCP proteins R-HSA-4608870
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog 'on' state R-HSA-5632684
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Class I MHC mediated antigen processing & presentation R-HSA-983169
MAPK family signaling cascades R-HSA-5683057
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S DNA Damage Checkpoints R-HSA-69615
MAPK6/MAPK4 signaling R-HSA-5687128
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular response to chemical stress R-HSA-9711123
Cytokine Signaling in Immune system R-HSA-1280215
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 signaling R-HSA-9020702
Neddylation R-HSA-8951664
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Assembly of the pre-replicative complex R-HSA-68867
Disorders of transmembrane transporters R-HSA-5619115
Signal Transduction R-HSA-162582
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transport of small molecules R-HSA-382551
UCH proteinases R-HSA-5689603
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of beta-catenin by the destruction complex R-HSA-195253
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of AXIN R-HSA-4641257
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of GLI1 by the proteasome R-HSA-5610780
PIP3 activates AKT signaling R-HSA-1257604
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Host Interactions of HIV factors R-HSA-162909
Cell Cycle, Mitotic R-HSA-69278
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by Interleukins R-HSA-449147
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular responses to stimuli R-HSA-8953897
Signaling by WNT R-HSA-195721
Apoptosis R-HSA-109581
Interferon Signaling R-HSA-913531
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hh mutants are degraded by ERAD R-HSA-5362768
HIV Infection R-HSA-162906
Post-translational protein modification R-HSA-597592
Hh mutants abrogate ligand secretion R-HSA-5387390
Hedgehog ligand biogenesis R-HSA-5358346
Disease R-HSA-1643685
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Adaptive Immune System R-HSA-1280218
Metabolism R-HSA-1430728
Activation of NF-kappaB in B cells R-HSA-1169091
Orc1 removal from chromatin R-HSA-68949
Signaling by Hedgehog R-HSA-5358351
Cellular responses to stress R-HSA-2262752
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of DVL R-HSA-4641258
MAPK1/MAPK3 signaling R-HSA-5684996
G1/S Transition R-HSA-69206
Ub-specific processing proteases R-HSA-5689880
Cell Cycle R-HSA-1640170
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Generic Transcription Pathway R-HSA-212436
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
RAF/MAP kinase cascade R-HSA-5673001
G2/M Transition R-HSA-69275
Nervous system development R-HSA-9675108
M Phase R-HSA-68886
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Innate Immune System R-HSA-168249
Regulation of RUNX3 expression and activity R-HSA-8941858
Immune System R-HSA-168256
Vpu mediated degradation of CD4 R-HSA-180534
S Phase R-HSA-69242
Signaling by NOTCH4 R-HSA-9013694
Regulation of mitotic cell cycle R-HSA-453276
PCP/CE pathway R-HSA-4086400
Metabolism of polyamines R-HSA-351202
PTEN Regulation R-HSA-6807070
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
DNA Replication Pre-Initiation R-HSA-69002
Interferon alpha/beta signaling R-HSA-909733
Interleukin-1 family signaling R-HSA-446652
Cellular response to hypoxia R-HSA-1234174
Regulation of RAS by GAPs R-HSA-5658442
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cell Cycle Checkpoints R-HSA-69620
Transcriptional regulation by RUNX3 R-HSA-8878159
ER-Phagosome pathway R-HSA-1236974
TCR signaling R-HSA-202403
Hedgehog 'off' state R-HSA-5610787
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Gene expression (Transcription) R-HSA-74160
Deubiquitination R-HSA-5688426
RNA Polymerase II Transcription R-HSA-73857
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Synthesis of DNA R-HSA-69239
Regulation of Apoptosis R-HSA-169911
ABC-family proteins mediated transport R-HSA-382556
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic Anaphase R-HSA-68882
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic G2-G2/M phases R-HSA-453274
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by NOTCH R-HSA-157118
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
FCERI mediated NF-kB activation R-HSA-2871837
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Antigen processing-Cross presentation R-HSA-1236975
Transcriptional regulation by RUNX2 R-HSA-8878166
Intracellular signaling by second messengers R-HSA-9006925
Vif-mediated degradation of APOBEC3G R-HSA-180585
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism of amino acids and derivatives R-HSA-71291
DNA Replication R-HSA-69306
Axon guidance R-HSA-422475
Signaling by ROBO receptors R-HSA-376176
Downstream TCR signaling R-HSA-202424
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
p53-Dependent G1 DNA Damage Response R-HSA-69563
Switching of origins to a post-replicative state R-HSA-69052
Developmental Biology R-HSA-1266738
Separation of Sister Chromatids R-HSA-2467813
DNA Replication Pre-Initiation R-HSA-69002
Hh mutants abrogate ligand secretion R-HSA-5387390
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by WNT R-HSA-195721
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RUNX3 expression and activity R-HSA-8941858
Switching of origins to a post-replicative state R-HSA-69052
Hedgehog 'off' state R-HSA-5610787
Separation of Sister Chromatids R-HSA-2467813
ER-Phagosome pathway R-HSA-1236974
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of polyamines R-HSA-351202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of DVL R-HSA-4641258
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nuclear events mediated by NFE2L2 R-HSA-9759194
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog 'on' state R-HSA-5632684
S Phase R-HSA-69242
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RAF/MAP kinase cascade R-HSA-5673001
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Adaptive Immune System R-HSA-1280218
Stabilization of p53 R-HSA-69541
Degradation of GLI2 by the proteasome R-HSA-5610783
Cellular responses to stress R-HSA-2262752
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
ABC-family proteins mediated transport R-HSA-382556
Metabolism of RNA R-HSA-8953854
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic Metaphase and Anaphase R-HSA-2555396
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transcriptional regulation by RUNX1 R-HSA-8878171
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disorders of transmembrane transporters R-HSA-5619115
Asymmetric localization of PCP proteins R-HSA-4608870
Mitotic G1 phase and G1/S transition R-HSA-453279
Vpu mediated degradation of CD4 R-HSA-180534
Immune System R-HSA-168256
Defective CFTR causes cystic fibrosis R-HSA-5678895
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of beta-catenin by the destruction complex R-HSA-195253
Innate Immune System R-HSA-168249
Cellular response to chemical stress R-HSA-9711123
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Assembly of the pre-replicative complex R-HSA-68867
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Vif-mediated degradation of APOBEC3G R-HSA-180585
TCF dependent signaling in response to WNT R-HSA-201681
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cytokine Signaling in Immune system R-HSA-1280215
Synthesis of DNA R-HSA-69239
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G2-G2/M phases R-HSA-453274
Downstream TCR signaling R-HSA-202424
G1/S Transition R-HSA-69206
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Anaphase R-HSA-68882
Metabolism of amino acids and derivatives R-HSA-71291
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Nervous system development R-HSA-9675108
Programmed Cell Death R-HSA-5357801
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by NOTCH R-HSA-157118
Cell Cycle R-HSA-1640170
Signaling by ROBO receptors R-HSA-376176
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
CLEC7A (Dectin-1) signaling R-HSA-5607764
DNA Replication R-HSA-69306
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of Apoptosis R-HSA-169911
Transport of small molecules R-HSA-382551
M Phase R-HSA-68886
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
PTEN Regulation R-HSA-6807070
Disease R-HSA-1643685
ABC transporter disorders R-HSA-5619084
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cellular responses to stimuli R-HSA-8953897
Regulation of expression of SLITs and ROBOs R-HSA-9010553
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
C-type lectin receptors (CLRs) R-HSA-5621481
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cell Cycle Checkpoints R-HSA-69620
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX2 R-HSA-8878166
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Generic Transcription Pathway R-HSA-212436
Ub-specific processing proteases R-HSA-5689880
Interleukin-1 signaling R-HSA-9020702
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by Interleukins R-HSA-449147
PCP/CE pathway R-HSA-4086400
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX3 R-HSA-8878159
PIP3 activates AKT signaling R-HSA-1257604
Degradation of GLI1 by the proteasome R-HSA-5610780
FCERI mediated NF-kB activation R-HSA-2871837
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Transition R-HSA-69275
Metabolism R-HSA-1430728
Interferon Signaling R-HSA-913531
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX2 expression and activity R-HSA-8939902
Apoptosis R-HSA-109581
Hh mutants are degraded by ERAD R-HSA-5362768
G2/M Checkpoints R-HSA-69481
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Post-translational protein modification R-HSA-597592
Neddylation R-HSA-8951664
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCR signaling R-HSA-202403
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Interferon alpha/beta signaling R-HSA-909733
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
UCH proteinases R-HSA-5689603
Signaling by NOTCH4 R-HSA-9013694
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Axon guidance R-HSA-422475
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular response to hypoxia R-HSA-1234174
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RNA Polymerase II Transcription R-HSA-73857
HIV Infection R-HSA-162906
Degradation of AXIN R-HSA-4641257
Cyclin E associated events during G1/S transition R-HSA-69202
Developmental Biology R-HSA-1266738
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog ligand biogenesis R-HSA-5358346
Host Interactions of HIV factors R-HSA-162909
Signaling by Hedgehog R-HSA-5358351
Deubiquitination R-HSA-5688426
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Signal Transduction R-HSA-162582
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Orc1 removal from chromatin R-HSA-68949
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of proteins R-HSA-392499
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Interleukins R-HSA-449147
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Asymmetric localization of PCP proteins R-HSA-4608870
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Adaptive Immune System R-HSA-1280218
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hedgehog ligand biogenesis R-HSA-5358346
Mitotic G2-G2/M phases R-HSA-453274
G1/S DNA Damage Checkpoints R-HSA-69615
Immune System R-HSA-168256
Class I MHC mediated antigen processing & presentation R-HSA-983169
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of GLI1 by the proteasome R-HSA-5610780
G2/M Transition R-HSA-69275
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by NOTCH R-HSA-157118
Developmental Biology R-HSA-1266738
Degradation of AXIN R-HSA-4641257
Disease R-HSA-1643685
Hh mutants abrogate ligand secretion R-HSA-5387390
C-type lectin receptors (CLRs) R-HSA-5621481
G2/M Checkpoints R-HSA-69481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
M Phase R-HSA-68886
Cellular response to chemical stress R-HSA-9711123
p53-Independent DNA Damage Response R-HSA-69610
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Programmed Cell Death R-HSA-5357801
Deubiquitination R-HSA-5688426
Transcriptional regulation by RUNX3 R-HSA-8878159
Interferon alpha/beta signaling R-HSA-909733
Signaling by Hedgehog R-HSA-5358351
UCH proteinases R-HSA-5689603
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of mitotic cell cycle R-HSA-453276
Metabolism R-HSA-1430728
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transport of small molecules R-HSA-382551
Regulation of RAS by GAPs R-HSA-5658442
Stabilization of p53 R-HSA-69541
CLEC7A (Dectin-1) signaling R-HSA-5607764
Separation of Sister Chromatids R-HSA-2467813
Regulation of Apoptosis R-HSA-169911
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
ABC-family proteins mediated transport R-HSA-382556
S Phase R-HSA-69242
HIV Infection R-HSA-162906
Antigen processing-Cross presentation R-HSA-1236975
Signaling by NOTCH4 R-HSA-9013694
TCR signaling R-HSA-202403
KEAP1-NFE2L2 pathway R-HSA-9755511
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of polyamines R-HSA-351202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear events mediated by NFE2L2 R-HSA-9759194
Post-translational protein modification R-HSA-597592
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
Switching of origins to a post-replicative state R-HSA-69052
DNA Replication Pre-Initiation R-HSA-69002
Metabolism of proteins R-HSA-392499
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of GLI2 by the proteasome R-HSA-5610783
Generic Transcription Pathway R-HSA-212436
Mitotic Anaphase R-HSA-68882
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
Synthesis of DNA R-HSA-69239
Interleukin-1 signaling R-HSA-9020702
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interleukin-1 family signaling R-HSA-446652
Vpu mediated degradation of CD4 R-HSA-180534
Axon guidance R-HSA-422475
Interferon Signaling R-HSA-913531
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cellular response to hypoxia R-HSA-1234174
Host Interactions of HIV factors R-HSA-162909
Signaling by ROBO receptors R-HSA-376176
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of RUNX2 expression and activity R-HSA-8939902
G1/S Transition R-HSA-69206
ER-Phagosome pathway R-HSA-1236974
Cell Cycle R-HSA-1640170
MAPK6/MAPK4 signaling R-HSA-5687128
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
TCF dependent signaling in response to WNT R-HSA-201681
MAPK family signaling cascades R-HSA-5683057
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular responses to stress R-HSA-2262752
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Beta-catenin independent WNT signaling R-HSA-3858494
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic Metaphase and Anaphase R-HSA-2555396
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism of amino acids and derivatives R-HSA-71291
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog 'on' state R-HSA-5632684
Ub-specific processing proteases R-HSA-5689880
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hedgehog 'off' state R-HSA-5610787
Activation of NF-kappaB in B cells R-HSA-1169091
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Disorders of transmembrane transporters R-HSA-5619115
Hh mutants are degraded by ERAD R-HSA-5362768
Negative regulation of NOTCH4 signaling R-HSA-9604323
FCERI mediated NF-kB activation R-HSA-2871837
Cell Cycle Checkpoints R-HSA-69620
Cell Cycle, Mitotic R-HSA-69278
Degradation of DVL R-HSA-4641258
Signal Transduction R-HSA-162582
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Downstream TCR signaling R-HSA-202424
Cellular responses to stimuli R-HSA-8953897
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of PTEN stability and activity R-HSA-8948751
ABC transporter disorders R-HSA-5619084
Orc1 removal from chromatin R-HSA-68949
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by WNT R-HSA-195721
PTEN Regulation R-HSA-6807070
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Apoptosis R-HSA-109581
DNA Replication R-HSA-69306
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX1 R-HSA-8878171
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Neddylation R-HSA-8951664
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Assembly of the pre-replicative complex R-HSA-68867
PCP/CE pathway R-HSA-4086400

Expression Atlas ENSG00000204264
LRG display in Ensembl gene LRG_1328
NCBI gene (formerly Entrezgene) 5696
GeneCards 9545
HGNC Symbol HGNC:9545
MIM gene 177046
MIM morbid 256040
UniProtKB Gene Name X5D2R7
WikiGene 5696
Gene: PSMB5
Ensembl ID : ENSG00000100804
Description: proteasome 20S subunit beta 5
Gene Synonyms: MB1
6 APIs:
218 Possible Orthologues:

ER-Phagosome pathway R-HSA-1236974
DNA Replication R-HSA-69306
Degradation of AXIN R-HSA-4641257
Degradation of GLI1 by the proteasome R-HSA-5610780
Axon guidance R-HSA-422475
Cell Cycle R-HSA-1640170
Cell Cycle Checkpoints R-HSA-69620
Stabilization of p53 R-HSA-69541
Interleukin-1 signaling R-HSA-9020702
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
G2/M Checkpoints R-HSA-69481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Mitotic Metaphase and Anaphase R-HSA-2555396
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
S Phase R-HSA-69242
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of amino acids and derivatives R-HSA-71291
Gene expression (Transcription) R-HSA-74160
Neddylation R-HSA-8951664
Assembly of the pre-replicative complex R-HSA-68867
Apoptosis R-HSA-109581
Metabolism of RNA R-HSA-8953854
Downstream TCR signaling R-HSA-202424
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of polyamines R-HSA-351202
G2/M Transition R-HSA-69275
Regulation of RUNX3 expression and activity R-HSA-8941858
Antigen processing-Cross presentation R-HSA-1236975
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Mitotic Anaphase R-HSA-68882
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FCERI mediated NF-kB activation R-HSA-2871837
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hedgehog ligand biogenesis R-HSA-5358346
Cellular response to hypoxia R-HSA-1234174
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic G1 phase and G1/S transition R-HSA-453279
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Host Interactions of HIV factors R-HSA-162909
G1/S DNA Damage Checkpoints R-HSA-69615
G1/S Transition R-HSA-69206
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hh mutants are degraded by ERAD R-HSA-5362768
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-1 family signaling R-HSA-446652
RNA Polymerase II Transcription R-HSA-73857
Regulation of PTEN stability and activity R-HSA-8948751
TCR signaling R-HSA-202403
Activation of NF-kappaB in B cells R-HSA-1169091
Immune System R-HSA-168256
PIP3 activates AKT signaling R-HSA-1257604
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Generic Transcription Pathway R-HSA-212436
Signaling by WNT R-HSA-195721
Deubiquitination R-HSA-5688426
Metabolism of proteins R-HSA-392499
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
p53-Independent DNA Damage Response R-HSA-69610
Innate Immune System R-HSA-168249
Hedgehog 'on' state R-HSA-5632684
Cellular responses to stress R-HSA-2262752
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stimuli R-HSA-8953897
Degradation of DVL R-HSA-4641258
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of Apoptosis R-HSA-169911
Adaptive Immune System R-HSA-1280218
KEAP1-NFE2L2 pathway R-HSA-9755511
Synthesis of DNA R-HSA-69239
Vif-mediated degradation of APOBEC3G R-HSA-180585
Separation of Sister Chromatids R-HSA-2467813
Cyclin E associated events during G1/S transition R-HSA-69202
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of mitotic cell cycle R-HSA-453276
Metabolism R-HSA-1430728
ABC transporter disorders R-HSA-5619084
DNA Replication R-HSA-69306
DNA Replication Pre-Initiation R-HSA-69002
Signaling by NOTCH4 R-HSA-9013694
Beta-catenin independent WNT signaling R-HSA-3858494
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX3 R-HSA-8878159
Switching of origins to a post-replicative state R-HSA-69052
C-type lectin receptors (CLRs) R-HSA-5621481
Disease R-HSA-1643685
RAF/MAP kinase cascade R-HSA-5673001
Hh mutants abrogate ligand secretion R-HSA-5387390
MAPK6/MAPK4 signaling R-HSA-5687128
Hedgehog 'off' state R-HSA-5610787
Ub-specific processing proteases R-HSA-5689880
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by ROBO receptors R-HSA-376176
Signaling by NOTCH R-HSA-157118
Signal Transduction R-HSA-162582
Signaling by Hedgehog R-HSA-5358351
Programmed Cell Death R-HSA-5357801
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
MAPK family signaling cascades R-HSA-5683057
TCF dependent signaling in response to WNT R-HSA-201681
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular response to chemical stress R-HSA-9711123
Regulation of RUNX2 expression and activity R-HSA-8939902
PCP/CE pathway R-HSA-4086400
HIV Infection R-HSA-162906
Asymmetric localization of PCP proteins R-HSA-4608870
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Developmental Biology R-HSA-1266738
Post-translational protein modification R-HSA-597592
Transport of small molecules R-HSA-382551
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of beta-catenin by the destruction complex R-HSA-195253
MAPK1/MAPK3 signaling R-HSA-5684996
p53-Dependent G1 DNA Damage Response R-HSA-69563
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Nervous system development R-HSA-9675108
M Phase R-HSA-68886
PTEN Regulation R-HSA-6807070
Mitotic G2-G2/M phases R-HSA-453274
Intracellular signaling by second messengers R-HSA-9006925
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cell Cycle, Mitotic R-HSA-69278
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
ABC-family proteins mediated transport R-HSA-382556
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX1 R-HSA-8878171
Disorders of transmembrane transporters R-HSA-5619115
Metabolism R-HSA-1430728
Signaling by NOTCH R-HSA-157118
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX1 R-HSA-8878171
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX3 R-HSA-8878159
Disorders of transmembrane transporters R-HSA-5619115
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
TCR signaling R-HSA-202403
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G1/S Transition R-HSA-69206
ABC transporter disorders R-HSA-5619084
Immune System R-HSA-168256
Gene expression (Transcription) R-HSA-74160
S Phase R-HSA-69242
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by Hedgehog R-HSA-5358351
Regulation of RUNX2 expression and activity R-HSA-8939902
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Switching of origins to a post-replicative state R-HSA-69052
Mitotic Metaphase and Anaphase R-HSA-2555396
Adaptive Immune System R-HSA-1280218
Host Interactions of HIV factors R-HSA-162909
G2/M Checkpoints R-HSA-69481
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic Anaphase R-HSA-68882
Activation of NF-kappaB in B cells R-HSA-1169091
Class I MHC mediated antigen processing & presentation R-HSA-983169
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic G2-G2/M phases R-HSA-453274
Separation of Sister Chromatids R-HSA-2467813
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular response to hypoxia R-HSA-1234174
Disease R-HSA-1643685
Cellular responses to stress R-HSA-2262752
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
MAPK family signaling cascades R-HSA-5683057
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Negative regulation of NOTCH4 signaling R-HSA-9604323
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Vpu mediated degradation of CD4 R-HSA-180534
Post-translational protein modification R-HSA-597592
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Intracellular signaling by second messengers R-HSA-9006925
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RAS by GAPs R-HSA-5658442
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Antigen processing-Cross presentation R-HSA-1236975
Hedgehog 'on' state R-HSA-5632684
ABC-family proteins mediated transport R-HSA-382556
Metabolism of polyamines R-HSA-351202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
MAPK6/MAPK4 signaling R-HSA-5687128
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Interleukin-1 family signaling R-HSA-446652
Cell Cycle R-HSA-1640170
PCP/CE pathway R-HSA-4086400
Generic Transcription Pathway R-HSA-212436
G2/M Transition R-HSA-69275
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Transport of small molecules R-HSA-382551
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of mitotic cell cycle R-HSA-453276
Innate Immune System R-HSA-168249
Developmental Biology R-HSA-1266738
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
Infectious disease R-HSA-5663205
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of Apoptosis R-HSA-169911
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
M Phase R-HSA-68886
ER-Phagosome pathway R-HSA-1236974
Assembly of the pre-replicative complex R-HSA-68867
Hedgehog 'off' state R-HSA-5610787
Metabolism of RNA R-HSA-8953854
RAF/MAP kinase cascade R-HSA-5673001
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
TCF dependent signaling in response to WNT R-HSA-201681
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
PTEN Regulation R-HSA-6807070
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of amino acids and derivatives R-HSA-71291
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by ROBO receptors R-HSA-376176
Hh mutants are degraded by ERAD R-HSA-5362768
PIP3 activates AKT signaling R-HSA-1257604
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Ub-specific processing proteases R-HSA-5689880
Cellular response to chemical stress R-HSA-9711123
Nervous system development R-HSA-9675108
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of AXIN R-HSA-4641257
p53-Independent DNA Damage Response R-HSA-69610
Neddylation R-HSA-8951664
Cytokine Signaling in Immune system R-HSA-1280215
DNA Replication Pre-Initiation R-HSA-69002
Orc1 removal from chromatin R-HSA-68949
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Programmed Cell Death R-HSA-5357801
p53-Dependent G1 DNA Damage Response R-HSA-69563
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Synthesis of DNA R-HSA-69239
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
UCH proteinases R-HSA-5689603
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Defective CFTR causes cystic fibrosis R-HSA-5678895
Stabilization of p53 R-HSA-69541
Signaling by Interleukins R-HSA-449147
Deubiquitination R-HSA-5688426
Apoptosis R-HSA-109581
RNA Polymerase II Transcription R-HSA-73857
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of DVL R-HSA-4641258
Hedgehog ligand biogenesis R-HSA-5358346
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI1 by the proteasome R-HSA-5610780
Interleukin-1 signaling R-HSA-9020702
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cell Cycle Checkpoints R-HSA-69620
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
Signaling by WNT R-HSA-195721
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of proteins R-HSA-392499
Signal Transduction R-HSA-162582
Regulation of PTEN stability and activity R-HSA-8948751
Downstream TCR signaling R-HSA-202424
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular responses to stimuli R-HSA-8953897
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Innate Immune System R-HSA-168249
Assembly of the pre-replicative complex R-HSA-68867
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Interleukin-1 signaling R-HSA-9020702
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
KEAP1-NFE2L2 pathway R-HSA-9755511
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
MAPK6/MAPK4 signaling R-HSA-5687128
Separation of Sister Chromatids R-HSA-2467813
Regulation of RUNX3 expression and activity R-HSA-8941858
G2/M Transition R-HSA-69275
Regulation of expression of SLITs and ROBOs R-HSA-9010553
TCF dependent signaling in response to WNT R-HSA-201681
Cytokine Signaling in Immune system R-HSA-1280215
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular response to hypoxia R-HSA-1234174
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cell Cycle R-HSA-1640170
ABC transporter disorders R-HSA-5619084
Degradation of GLI2 by the proteasome R-HSA-5610783
Asymmetric localization of PCP proteins R-HSA-4608870
DNA Replication R-HSA-69306
Hedgehog 'on' state R-HSA-5632684
HIV Infection R-HSA-162906
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of RUNX2 expression and activity R-HSA-8939902
CLEC7A (Dectin-1) signaling R-HSA-5607764
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Hedgehog R-HSA-5358351
Degradation of AXIN R-HSA-4641257
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Negative regulation of NOTCH4 signaling R-HSA-9604323
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular responses to stimuli R-HSA-8953897
Metabolism of RNA R-HSA-8953854
Interleukin-1 family signaling R-HSA-446652
G1/S DNA Damage Checkpoints R-HSA-69615
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of PTEN stability and activity R-HSA-8948751
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of polyamines R-HSA-351202
DNA Replication Pre-Initiation R-HSA-69002
Degradation of DVL R-HSA-4641258
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cellular responses to stress R-HSA-2262752
ER-Phagosome pathway R-HSA-1236974
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Adaptive Immune System R-HSA-1280218
Hh mutants are degraded by ERAD R-HSA-5362768
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hedgehog 'off' state R-HSA-5610787
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hh mutants abrogate ligand secretion R-HSA-5387390
Signaling by WNT R-HSA-195721
FCERI mediated NF-kB activation R-HSA-2871837
Switching of origins to a post-replicative state R-HSA-69052
Regulation of Apoptosis R-HSA-169911
Transport of small molecules R-HSA-382551
Metabolism of amino acids and derivatives R-HSA-71291
Intracellular signaling by second messengers R-HSA-9006925
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Disorders of transmembrane transporters R-HSA-5619115
Synthesis of DNA R-HSA-69239
Immune System R-HSA-168256
Downstream TCR signaling R-HSA-202424
Antigen processing-Cross presentation R-HSA-1236975
p53-Independent DNA Damage Response R-HSA-69610
Nuclear events mediated by NFE2L2 R-HSA-9759194
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
S Phase R-HSA-69242
PCP/CE pathway R-HSA-4086400
Mitotic G2-G2/M phases R-HSA-453274
Infectious disease R-HSA-5663205
Hedgehog ligand biogenesis R-HSA-5358346
Ub-specific processing proteases R-HSA-5689880
Developmental Biology R-HSA-1266738
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Degradation of GLI1 by the proteasome R-HSA-5610780
Disease R-HSA-1643685
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Beta-catenin independent WNT signaling R-HSA-3858494
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Host Interactions of HIV factors R-HSA-162909
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell Cycle Checkpoints R-HSA-69620
Deubiquitination R-HSA-5688426
Apoptosis R-HSA-109581
Mitotic Anaphase R-HSA-68882
Programmed Cell Death R-HSA-5357801
Signaling by Interleukins R-HSA-449147
TCR signaling R-HSA-202403
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
MAPK family signaling cascades R-HSA-5683057
G1/S Transition R-HSA-69206
Regulation of mitotic cell cycle R-HSA-453276
Transcriptional regulation by RUNX3 R-HSA-8878159
C-type lectin receptors (CLRs) R-HSA-5621481
Orc1 removal from chromatin R-HSA-68949
Signaling by ROBO receptors R-HSA-376176
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by NOTCH4 R-HSA-9013694
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of RAS by GAPs R-HSA-5658442
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by NOTCH R-HSA-157118
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Defective CFTR causes cystic fibrosis R-HSA-5678895
RNA Polymerase II Transcription R-HSA-73857
Stabilization of p53 R-HSA-69541
ABC-family proteins mediated transport R-HSA-382556
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Gene expression (Transcription) R-HSA-74160
Metabolism R-HSA-1430728
Nervous system development R-HSA-9675108
UCH proteinases R-HSA-5689603
Cellular response to chemical stress R-HSA-9711123
Post-translational protein modification R-HSA-597592
G2/M Checkpoints R-HSA-69481
Axon guidance R-HSA-422475
Cell Cycle, Mitotic R-HSA-69278
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RAF/MAP kinase cascade R-HSA-5673001
Class I MHC mediated antigen processing & presentation R-HSA-983169
Generic Transcription Pathway R-HSA-212436
PTEN Regulation R-HSA-6807070
M Phase R-HSA-68886
Vpu mediated degradation of CD4 R-HSA-180534
Signal Transduction R-HSA-162582
Activation of NF-kappaB in B cells R-HSA-1169091
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Neddylation R-HSA-8951664
Metabolism of proteins R-HSA-392499
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by WNT R-HSA-195721
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of proteins R-HSA-392499
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Mitotic G2-G2/M phases R-HSA-453274
Downstream TCR signaling R-HSA-202424
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Innate Immune System R-HSA-168249
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cellular responses to stimuli R-HSA-8953897
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism of polyamines R-HSA-351202
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Apoptosis R-HSA-109581
Signal Transduction R-HSA-162582
Mitotic Anaphase R-HSA-68882
MAPK1/MAPK3 signaling R-HSA-5684996
Beta-catenin independent WNT signaling R-HSA-3858494
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of mitotic cell cycle R-HSA-453276
ABC transporter disorders R-HSA-5619084
Class I MHC mediated antigen processing & presentation R-HSA-983169
M Phase R-HSA-68886
Transcriptional regulation by RUNX3 R-HSA-8878159
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
TCF dependent signaling in response to WNT R-HSA-201681
Gene expression (Transcription) R-HSA-74160
MAPK6/MAPK4 signaling R-HSA-5687128
Nervous system development R-HSA-9675108
Signaling by NOTCH R-HSA-157118
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
UCH proteinases R-HSA-5689603
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Asymmetric localization of PCP proteins R-HSA-4608870
HIV Infection R-HSA-162906
Regulation of RAS by GAPs R-HSA-5658442
Degradation of DVL R-HSA-4641258
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cell Cycle Checkpoints R-HSA-69620
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by Interleukins R-HSA-449147
Vpu mediated degradation of CD4 R-HSA-180534
Nuclear events mediated by NFE2L2 R-HSA-9759194
Adaptive Immune System R-HSA-1280218
Host Interactions of HIV factors R-HSA-162909
Infectious disease R-HSA-5663205
Disorders of transmembrane transporters R-HSA-5619115
Transport of small molecules R-HSA-382551
Cyclin E associated events during G1/S transition R-HSA-69202
PTEN Regulation R-HSA-6807070
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cellular response to chemical stress R-HSA-9711123
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
G2/M Checkpoints R-HSA-69481
Degradation of GLI2 by the proteasome R-HSA-5610783
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Interleukin-1 signaling R-HSA-9020702
FCERI mediated NF-kB activation R-HSA-2871837
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Ub-specific processing proteases R-HSA-5689880
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of beta-catenin by the destruction complex R-HSA-195253
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cell Cycle, Mitotic R-HSA-69278
Axon guidance R-HSA-422475
Signaling by NOTCH4 R-HSA-9013694
ER-Phagosome pathway R-HSA-1236974
Separation of Sister Chromatids R-HSA-2467813
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hedgehog ligand biogenesis R-HSA-5358346
S Phase R-HSA-69242
RAF/MAP kinase cascade R-HSA-5673001
Cellular response to hypoxia R-HSA-1234174
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism of RNA R-HSA-8953854
PCP/CE pathway R-HSA-4086400
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Disease R-HSA-1643685
Signaling by the B Cell Receptor (BCR) R-HSA-983705
DNA Replication R-HSA-69306
Deubiquitination R-HSA-5688426
Immune System R-HSA-168256
Switching of origins to a post-replicative state R-HSA-69052
CLEC7A (Dectin-1) signaling R-HSA-5607764
MAPK family signaling cascades R-HSA-5683057
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of RUNX3 expression and activity R-HSA-8941858
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
G1/S DNA Damage Checkpoints R-HSA-69615
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Orc1 removal from chromatin R-HSA-68949
Synthesis of DNA R-HSA-69239
TCR signaling R-HSA-202403
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Developmental Biology R-HSA-1266738
PIP3 activates AKT signaling R-HSA-1257604
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX1 R-HSA-8878171
Generic Transcription Pathway R-HSA-212436
Regulation of PTEN stability and activity R-HSA-8948751
Hedgehog 'off' state R-HSA-5610787
p53-Independent DNA Damage Response R-HSA-69610
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Stabilization of p53 R-HSA-69541
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of AXIN R-HSA-4641257
C-type lectin receptors (CLRs) R-HSA-5621481
G2/M Transition R-HSA-69275
Signaling by Hedgehog R-HSA-5358351
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hedgehog 'on' state R-HSA-5632684
Neddylation R-HSA-8951664
p53-Dependent G1 DNA Damage Response R-HSA-69563
Interleukin-1 family signaling R-HSA-446652
Programmed Cell Death R-HSA-5357801
Negative regulation of NOTCH4 signaling R-HSA-9604323
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC-family proteins mediated transport R-HSA-382556
Cytokine Signaling in Immune system R-HSA-1280215
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of GLI1 by the proteasome R-HSA-5610780
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G1/S Transition R-HSA-69206
Transcriptional regulation by RUNX2 R-HSA-8878166
Post-translational protein modification R-HSA-597592
DNA Replication Pre-Initiation R-HSA-69002
Cellular responses to stress R-HSA-2262752
Signaling by ROBO receptors R-HSA-376176
Assembly of the pre-replicative complex R-HSA-68867
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism R-HSA-1430728
Metabolism of amino acids and derivatives R-HSA-71291
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle R-HSA-1640170
Regulation of Apoptosis R-HSA-169911
Degradation of AXIN R-HSA-4641257
Generic Transcription Pathway R-HSA-212436
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Antigen processing-Cross presentation R-HSA-1236975
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signal Transduction R-HSA-162582
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK family signaling cascades R-HSA-5683057
Ub-specific processing proteases R-HSA-5689880
p53-Dependent G1 DNA Damage Response R-HSA-69563
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Asymmetric localization of PCP proteins R-HSA-4608870
UCH proteinases R-HSA-5689603
FCERI mediated NF-kB activation R-HSA-2871837
Cell Cycle R-HSA-1640170
Downstream TCR signaling R-HSA-202424
Orc1 removal from chromatin R-HSA-68949
Switching of origins to a post-replicative state R-HSA-69052
Signaling by NOTCH R-HSA-157118
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TCF dependent signaling in response to WNT R-HSA-201681
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
MAPK1/MAPK3 signaling R-HSA-5684996
Hedgehog 'off' state R-HSA-5610787
KEAP1-NFE2L2 pathway R-HSA-9755511
PCP/CE pathway R-HSA-4086400
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX3 R-HSA-8878159
DNA Replication R-HSA-69306
Regulation of Apoptosis R-HSA-169911
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of mitotic cell cycle R-HSA-453276
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Synthesis of DNA R-HSA-69239
Interleukin-1 family signaling R-HSA-446652
Neddylation R-HSA-8951664
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
MAPK6/MAPK4 signaling R-HSA-5687128
Post-translational protein modification R-HSA-597592
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signaling by NOTCH4 R-HSA-9013694
Immune System R-HSA-168256
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
ABC-family proteins mediated transport R-HSA-382556
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of RNA R-HSA-8953854
Metabolism R-HSA-1430728
RNA Polymerase II Transcription R-HSA-73857
G2/M Checkpoints R-HSA-69481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Axon guidance R-HSA-422475
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by Interleukins R-HSA-449147
M Phase R-HSA-68886
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX2 expression and activity R-HSA-8939902
Apoptosis R-HSA-109581
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
RAF/MAP kinase cascade R-HSA-5673001
DNA Replication Pre-Initiation R-HSA-69002
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular responses to stimuli R-HSA-8953897
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Class I MHC mediated antigen processing & presentation R-HSA-983169
CLEC7A (Dectin-1) signaling R-HSA-5607764
Transcriptional regulation by RUNX1 R-HSA-8878171
Stabilization of p53 R-HSA-69541
Programmed Cell Death R-HSA-5357801
Disorders of transmembrane transporters R-HSA-5619115
Regulation of RUNX3 expression and activity R-HSA-8941858
Interleukin-1 signaling R-HSA-9020702
S Phase R-HSA-69242
TCR signaling R-HSA-202403
Metabolism of amino acids and derivatives R-HSA-71291
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Degradation of beta-catenin by the destruction complex R-HSA-195253
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Defective CFTR causes cystic fibrosis R-HSA-5678895
Nervous system development R-HSA-9675108
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by WNT R-HSA-195721
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G2/M Transition R-HSA-69275
Degradation of DVL R-HSA-4641258
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Separation of Sister Chromatids R-HSA-2467813
Transport of small molecules R-HSA-382551
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic G2-G2/M phases R-HSA-453274
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog 'on' state R-HSA-5632684
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Degradation of GLI2 by the proteasome R-HSA-5610783
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Adaptive Immune System R-HSA-1280218
Signaling by ROBO receptors R-HSA-376176
Hedgehog ligand biogenesis R-HSA-5358346
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Vpu mediated degradation of CD4 R-HSA-180534
Gene expression (Transcription) R-HSA-74160
Regulation of RAS by GAPs R-HSA-5658442
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Independent DNA Damage Response R-HSA-69610
PIP3 activates AKT signaling R-HSA-1257604
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Host Interactions of HIV factors R-HSA-162909
Assembly of the pre-replicative complex R-HSA-68867
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic Anaphase R-HSA-68882
Disease R-HSA-1643685
ER-Phagosome pathway R-HSA-1236974
Cellular response to chemical stress R-HSA-9711123
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Metabolism of polyamines R-HSA-351202
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
C-type lectin receptors (CLRs) R-HSA-5621481
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G1/S Transition R-HSA-69206
Negative regulation of NOTCH4 signaling R-HSA-9604323
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by Hedgehog R-HSA-5358351
HIV Infection R-HSA-162906
ABC transporter disorders R-HSA-5619084
Hh mutants abrogate ligand secretion R-HSA-5387390
PTEN Regulation R-HSA-6807070
Cell Cycle Checkpoints R-HSA-69620
Metabolism of proteins R-HSA-392499
Beta-catenin independent WNT signaling R-HSA-3858494
Cell Cycle, Mitotic R-HSA-69278
Deubiquitination R-HSA-5688426
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
G1/S DNA Damage Checkpoints R-HSA-69615
Mitotic Metaphase and Anaphase R-HSA-2555396
Cellular response to hypoxia R-HSA-1234174
MAPK family signaling cascades R-HSA-5683057
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
ABC-family proteins mediated transport R-HSA-382556
Immune System R-HSA-168256
Class I MHC mediated antigen processing & presentation R-HSA-983169
Host Interactions of HIV factors R-HSA-162909
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX1 R-HSA-8878171
Hedgehog ligand biogenesis R-HSA-5358346
Assembly of the pre-replicative complex R-HSA-68867
PIP3 activates AKT signaling R-HSA-1257604
MAPK6/MAPK4 signaling R-HSA-5687128
Mitotic Anaphase R-HSA-68882
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Deubiquitination R-HSA-5688426
Apoptosis R-HSA-109581
TCF dependent signaling in response to WNT R-HSA-201681
MAPK1/MAPK3 signaling R-HSA-5684996
Activation of NF-kappaB in B cells R-HSA-1169091
Developmental Biology R-HSA-1266738
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by Hedgehog R-HSA-5358351
Metabolism of proteins R-HSA-392499
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Transition R-HSA-69275
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by Interleukins R-HSA-449147
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by NOTCH R-HSA-157118
Hedgehog 'on' state R-HSA-5632684
Switching of origins to a post-replicative state R-HSA-69052
Degradation of AXIN R-HSA-4641257
Metabolism of polyamines R-HSA-351202
Adaptive Immune System R-HSA-1280218
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
S Phase R-HSA-69242
FCERI mediated NF-kB activation R-HSA-2871837
p53-Dependent G1 DNA Damage Response R-HSA-69563
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of beta-catenin by the destruction complex R-HSA-195253
G1/S Transition R-HSA-69206
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of GLI1 by the proteasome R-HSA-5610780
Cellular response to hypoxia R-HSA-1234174
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of mitotic cell cycle R-HSA-453276
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Infectious disease R-HSA-5663205
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX2 R-HSA-8878166
Synthesis of DNA R-HSA-69239
Neddylation R-HSA-8951664
HIV Infection R-HSA-162906
PCP/CE pathway R-HSA-4086400
Beta-catenin independent WNT signaling R-HSA-3858494
p53-Independent DNA Damage Response R-HSA-69610
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
PTEN Regulation R-HSA-6807070
C-type lectin receptors (CLRs) R-HSA-5621481
Signal Transduction R-HSA-162582
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cytokine Signaling in Immune system R-HSA-1280215
Cell Cycle Checkpoints R-HSA-69620
Cellular responses to stress R-HSA-2262752
G2/M Checkpoints R-HSA-69481
M Phase R-HSA-68886
Downstream TCR signaling R-HSA-202424
Interleukin-1 family signaling R-HSA-446652
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism of RNA R-HSA-8953854
Degradation of DVL R-HSA-4641258
DNA Replication R-HSA-69306
Defective CFTR causes cystic fibrosis R-HSA-5678895
CLEC7A (Dectin-1) signaling R-HSA-5607764
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Gene expression (Transcription) R-HSA-74160
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of amino acids and derivatives R-HSA-71291
Nervous system development R-HSA-9675108
Regulation of PTEN stability and activity R-HSA-8948751
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Vpu mediated degradation of CD4 R-HSA-180534
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Innate Immune System R-HSA-168249
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants are degraded by ERAD R-HSA-5362768
Disease R-HSA-1643685
Cell Cycle R-HSA-1640170
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Programmed Cell Death R-HSA-5357801
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cell Cycle, Mitotic R-HSA-69278
Cellular response to chemical stress R-HSA-9711123
Intracellular signaling by second messengers R-HSA-9006925
Asymmetric localization of PCP proteins R-HSA-4608870
G1/S DNA Damage Checkpoints R-HSA-69615
Stabilization of p53 R-HSA-69541
Signaling by WNT R-HSA-195721
Signaling by NOTCH4 R-HSA-9013694
Cellular responses to stimuli R-HSA-8953897
Post-translational protein modification R-HSA-597592
Negative regulation of NOTCH4 signaling R-HSA-9604323
Vif-mediated degradation of APOBEC3G R-HSA-180585
DNA Replication Pre-Initiation R-HSA-69002
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transport of small molecules R-HSA-382551
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RNA Polymerase II Transcription R-HSA-73857
Antigen processing-Cross presentation R-HSA-1236975
RAF/MAP kinase cascade R-HSA-5673001
Regulation of RUNX3 expression and activity R-HSA-8941858
Axon guidance R-HSA-422475
Hedgehog 'off' state R-HSA-5610787
UCH proteinases R-HSA-5689603
TCR signaling R-HSA-202403
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism R-HSA-1430728
Ub-specific processing proteases R-HSA-5689880
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by ROBO receptors R-HSA-376176
Regulation of Apoptosis R-HSA-169911
Interleukin-1 signaling R-HSA-9020702
Disorders of transmembrane transporters R-HSA-5619115
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Generic Transcription Pathway R-HSA-212436
Regulation of expression of SLITs and ROBOs R-HSA-9010553
ER-Phagosome pathway R-HSA-1236974
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G2-G2/M phases R-HSA-453274
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Separation of Sister Chromatids R-HSA-2467813
Orc1 removal from chromatin R-HSA-68949
Degradation of GLI2 by the proteasome R-HSA-5610783
Cellular response to chemical stress R-HSA-9711123
Metabolism of RNA R-HSA-8953854
MAPK6/MAPK4 signaling R-HSA-5687128
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
PIP3 activates AKT signaling R-HSA-1257604
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cytokine Signaling in Immune system R-HSA-1280215
Disease R-HSA-1643685
M Phase R-HSA-68886
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH4 R-HSA-9013694
Generic Transcription Pathway R-HSA-212436
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hedgehog 'off' state R-HSA-5610787
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
G1/S DNA Damage Checkpoints R-HSA-69615
Post-translational protein modification R-HSA-597592
Cell Cycle R-HSA-1640170
DNA Replication Pre-Initiation R-HSA-69002
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hedgehog 'on' state R-HSA-5632684
Transport of small molecules R-HSA-382551
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Host Interactions of HIV factors R-HSA-162909
Cellular response to hypoxia R-HSA-1234174
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by Interleukins R-HSA-449147
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Nervous system development R-HSA-9675108
Mitotic G1 phase and G1/S transition R-HSA-453279
Hh mutants are degraded by ERAD R-HSA-5362768
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
RAF/MAP kinase cascade R-HSA-5673001
Stabilization of p53 R-HSA-69541
Degradation of AXIN R-HSA-4641257
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of polyamines R-HSA-351202
Interleukin-1 family signaling R-HSA-446652
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Separation of Sister Chromatids R-HSA-2467813
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transcriptional regulation by RUNX2 R-HSA-8878166
Gene expression (Transcription) R-HSA-74160
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
ABC-family proteins mediated transport R-HSA-382556
Degradation of GLI2 by the proteasome R-HSA-5610783
Degradation of DVL R-HSA-4641258
PTEN Regulation R-HSA-6807070
Signaling by Hedgehog R-HSA-5358351
Signaling by WNT R-HSA-195721
UCH proteinases R-HSA-5689603
Degradation of beta-catenin by the destruction complex R-HSA-195253
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of RUNX2 expression and activity R-HSA-8939902
Signal Transduction R-HSA-162582
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of RUNX3 expression and activity R-HSA-8941858
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism of proteins R-HSA-392499
ABC transporter disorders R-HSA-5619084
Apoptosis R-HSA-109581
Disorders of transmembrane transporters R-HSA-5619115
Adaptive Immune System R-HSA-1280218
Regulation of mitotic cell cycle R-HSA-453276
Defective CFTR causes cystic fibrosis R-HSA-5678895
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by ROBO receptors R-HSA-376176
Orc1 removal from chromatin R-HSA-68949
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Independent DNA Damage Response R-HSA-69610
RNA Polymerase II Transcription R-HSA-73857
Synthesis of DNA R-HSA-69239
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cell Cycle Checkpoints R-HSA-69620
Activation of NF-kappaB in B cells R-HSA-1169091
Mitotic Anaphase R-HSA-68882
Metabolism of amino acids and derivatives R-HSA-71291
Switching of origins to a post-replicative state R-HSA-69052
Intracellular signaling by second messengers R-HSA-9006925
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
p53-Dependent G1 DNA Damage Response R-HSA-69563
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
G2/M Checkpoints R-HSA-69481
Mitotic G2-G2/M phases R-HSA-453274
Vpu mediated degradation of CD4 R-HSA-180534
Antigen processing-Cross presentation R-HSA-1236975
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RAS by GAPs R-HSA-5658442
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PCP/CE pathway R-HSA-4086400
Assembly of the pre-replicative complex R-HSA-68867
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX1 R-HSA-8878171
Vif-mediated degradation of APOBEC3G R-HSA-180585
NIK-->noncanonical NF-kB signaling R-HSA-5676590
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
G2/M Transition R-HSA-69275
Interleukin-1 signaling R-HSA-9020702
Cellular responses to stimuli R-HSA-8953897
HIV Infection R-HSA-162906
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of Apoptosis R-HSA-169911
CLEC7A (Dectin-1) signaling R-HSA-5607764
TCR signaling R-HSA-202403
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Deubiquitination R-HSA-5688426
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of expression of SLITs and ROBOs R-HSA-9010553
S Phase R-HSA-69242
MAPK family signaling cascades R-HSA-5683057
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
KEAP1-NFE2L2 pathway R-HSA-9755511
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Nuclear events mediated by NFE2L2 R-HSA-9759194
Ub-specific processing proteases R-HSA-5689880
FCERI mediated NF-kB activation R-HSA-2871837
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cyclin E associated events during G1/S transition R-HSA-69202
Axon guidance R-HSA-422475
Downstream TCR signaling R-HSA-202424
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism R-HSA-1430728
Signaling by NOTCH R-HSA-157118
Innate Immune System R-HSA-168249
Hedgehog ligand biogenesis R-HSA-5358346
Neddylation R-HSA-8951664
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
DNA Replication R-HSA-69306
C-type lectin receptors (CLRs) R-HSA-5621481
Infectious disease R-HSA-5663205
Degradation of GLI1 by the proteasome R-HSA-5610780
G1/S Transition R-HSA-69206
Immune System R-HSA-168256
MAPK1/MAPK3 signaling R-HSA-5684996
Developmental Biology R-HSA-1266738
ER-Phagosome pathway R-HSA-1236974
Cell Cycle, Mitotic R-HSA-69278
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Transcriptional regulation by RUNX3 R-HSA-8878159
ABC transporter disorders R-HSA-5619084
Programmed Cell Death R-HSA-5357801
Degradation of AXIN R-HSA-4641257
Downstream TCR signaling R-HSA-202424
Deubiquitination R-HSA-5688426
Hedgehog 'off' state R-HSA-5610787
G2/M Transition R-HSA-69275
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
KEAP1-NFE2L2 pathway R-HSA-9755511
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hh mutants are degraded by ERAD R-HSA-5362768
p53-Independent DNA Damage Response R-HSA-69610
Nuclear events mediated by NFE2L2 R-HSA-9759194
Neddylation R-HSA-8951664
Assembly of the pre-replicative complex R-HSA-68867
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Generic Transcription Pathway R-HSA-212436
Cell Cycle R-HSA-1640170
Cyclin E associated events during G1/S transition R-HSA-69202
Metabolism of polyamines R-HSA-351202
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cellular responses to stimuli R-HSA-8953897
Immune System R-HSA-168256
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of GLI2 by the proteasome R-HSA-5610783
Vpu mediated degradation of CD4 R-HSA-180534
Cellular response to chemical stress R-HSA-9711123
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S Transition R-HSA-69206
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of Apoptosis R-HSA-169911
Interleukin-1 signaling R-HSA-9020702
Signal Transduction R-HSA-162582
ER-Phagosome pathway R-HSA-1236974
ABC-family proteins mediated transport R-HSA-382556
Mitotic Anaphase R-HSA-68882
Degradation of DVL R-HSA-4641258
S Phase R-HSA-69242
Hedgehog 'on' state R-HSA-5632684
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Infectious disease R-HSA-5663205
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PTEN Regulation R-HSA-6807070
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
MAPK6/MAPK4 signaling R-HSA-5687128
Synthesis of DNA R-HSA-69239
Signaling by NOTCH4 R-HSA-9013694
Intracellular signaling by second messengers R-HSA-9006925
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
DNA Replication R-HSA-69306
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Vif-mediated degradation of APOBEC3G R-HSA-180585
Activation of NF-kappaB in B cells R-HSA-1169091
Interleukin-1 family signaling R-HSA-446652
Metabolism of RNA R-HSA-8953854
C-type lectin receptors (CLRs) R-HSA-5621481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cell Cycle Checkpoints R-HSA-69620
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of RUNX2 expression and activity R-HSA-8939902
PCP/CE pathway R-HSA-4086400
Cytokine Signaling in Immune system R-HSA-1280215
Nervous system development R-HSA-9675108
FCERI mediated NF-kB activation R-HSA-2871837
Cellular response to hypoxia R-HSA-1234174
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism R-HSA-1430728
Orc1 removal from chromatin R-HSA-68949
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Mitotic G1 phase and G1/S transition R-HSA-453279
M Phase R-HSA-68886
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Stabilization of p53 R-HSA-69541
RAF/MAP kinase cascade R-HSA-5673001
DNA Replication Pre-Initiation R-HSA-69002
Transport of small molecules R-HSA-382551
Host Interactions of HIV factors R-HSA-162909
HIV Infection R-HSA-162906
Signaling by ROBO receptors R-HSA-376176
Regulation of RAS by GAPs R-HSA-5658442
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Gene expression (Transcription) R-HSA-74160
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Separation of Sister Chromatids R-HSA-2467813
Regulation of mitotic cell cycle R-HSA-453276
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transcriptional regulation by RUNX2 R-HSA-8878166
Hh mutants abrogate ligand secretion R-HSA-5387390
Axon guidance R-HSA-422475
Disease R-HSA-1643685
G1/S DNA Damage Checkpoints R-HSA-69615
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Adaptive Immune System R-HSA-1280218
Cell Cycle, Mitotic R-HSA-69278
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of amino acids and derivatives R-HSA-71291
MAPK1/MAPK3 signaling R-HSA-5684996
Apoptosis R-HSA-109581
Mitotic G2-G2/M phases R-HSA-453274
Metabolism of proteins R-HSA-392499
Signaling by WNT R-HSA-195721
PIP3 activates AKT signaling R-HSA-1257604
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Innate Immune System R-HSA-168249
UCH proteinases R-HSA-5689603
Disorders of transmembrane transporters R-HSA-5619115
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TCR signaling R-HSA-202403
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog ligand biogenesis R-HSA-5358346
Class I MHC mediated antigen processing & presentation R-HSA-983169
Negative regulation of NOTCH4 signaling R-HSA-9604323
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ub-specific processing proteases R-HSA-5689880
Signaling by Interleukins R-HSA-449147
RNA Polymerase II Transcription R-HSA-73857
Post-translational protein modification R-HSA-597592
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transcriptional regulation by RUNX1 R-HSA-8878171
Antigen processing-Cross presentation R-HSA-1236975
Regulation of PTEN stability and activity R-HSA-8948751
Beta-catenin independent WNT signaling R-HSA-3858494
Developmental Biology R-HSA-1266738
MAPK family signaling cascades R-HSA-5683057
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by NOTCH R-HSA-157118
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by Hedgehog R-HSA-5358351
Cellular responses to stress R-HSA-2262752
G2/M Checkpoints R-HSA-69481
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Switching of origins to a post-replicative state R-HSA-69052
Metabolism R-HSA-1430728
TCF dependent signaling in response to WNT R-HSA-201681
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PIP3 activates AKT signaling R-HSA-1257604
Signaling by ROBO receptors R-HSA-376176
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signal Transduction R-HSA-162582
Adaptive Immune System R-HSA-1280218
Developmental Biology R-HSA-1266738
Nuclear events mediated by NFE2L2 R-HSA-9759194
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by Hedgehog R-HSA-5358351
Innate Immune System R-HSA-168249
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Degradation of AXIN R-HSA-4641257
Transcriptional regulation by RUNX1 R-HSA-8878171
Nervous system development R-HSA-9675108
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular response to chemical stress R-HSA-9711123
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of RUNX2 expression and activity R-HSA-8939902
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX2 R-HSA-8878166
Hedgehog 'off' state R-HSA-5610787
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
DNA Replication Pre-Initiation R-HSA-69002
Neddylation R-HSA-8951664
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of beta-catenin by the destruction complex R-HSA-195253
G1/S Transition R-HSA-69206
Signaling by NOTCH R-HSA-157118
HIV Infection R-HSA-162906
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Deubiquitination R-HSA-5688426
RNA Polymerase II Transcription R-HSA-73857
S Phase R-HSA-69242
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
KEAP1-NFE2L2 pathway R-HSA-9755511
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Disorders of transmembrane transporters R-HSA-5619115
Post-translational protein modification R-HSA-597592
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular responses to stress R-HSA-2262752
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ER-Phagosome pathway R-HSA-1236974
Metabolism of RNA R-HSA-8953854
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism of polyamines R-HSA-351202
Signaling by NOTCH4 R-HSA-9013694
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
RAF/MAP kinase cascade R-HSA-5673001
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Apoptosis R-HSA-109581
Regulation of mitotic cell cycle R-HSA-453276
Regulation of PTEN stability and activity R-HSA-8948751
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Infectious disease R-HSA-5663205
Metabolism of proteins R-HSA-392499
FCERI mediated NF-kB activation R-HSA-2871837
Transcriptional regulation by RUNX3 R-HSA-8878159
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Independent DNA Damage Response R-HSA-69610
Disease R-HSA-1643685
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
ABC-family proteins mediated transport R-HSA-382556
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic Metaphase and Anaphase R-HSA-2555396
Interleukin-1 signaling R-HSA-9020702
Asymmetric localization of PCP proteins R-HSA-4608870
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Transport of small molecules R-HSA-382551
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular responses to stimuli R-HSA-8953897
Degradation of GLI2 by the proteasome R-HSA-5610783
G2/M Transition R-HSA-69275
Antigen processing-Cross presentation R-HSA-1236975
Degradation of DVL R-HSA-4641258
Gene expression (Transcription) R-HSA-74160
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cell Cycle R-HSA-1640170
Cell Cycle Checkpoints R-HSA-69620
Cyclin E associated events during G1/S transition R-HSA-69202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Programmed Cell Death R-HSA-5357801
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Dependent G1 DNA Damage Response R-HSA-69563
PTEN Regulation R-HSA-6807070
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
MAPK family signaling cascades R-HSA-5683057
Activation of NF-kappaB in B cells R-HSA-1169091
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Hedgehog 'on' state R-HSA-5632684
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog ligand biogenesis R-HSA-5358346
TCR signaling R-HSA-202403
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G2/M Checkpoints R-HSA-69481
Cytokine Signaling in Immune system R-HSA-1280215
Intracellular signaling by second messengers R-HSA-9006925
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S DNA Damage Checkpoints R-HSA-69615
UCH proteinases R-HSA-5689603
Regulation of RAS by GAPs R-HSA-5658442
ABC transporter disorders R-HSA-5619084
M Phase R-HSA-68886
Degradation of GLI1 by the proteasome R-HSA-5610780
Immune System R-HSA-168256
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by Interleukins R-HSA-449147
Hh mutants abrogate ligand secretion R-HSA-5387390
Downstream TCR signaling R-HSA-202424
Regulation of Apoptosis R-HSA-169911
Mitotic Anaphase R-HSA-68882
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic G2-G2/M phases R-HSA-453274
C-type lectin receptors (CLRs) R-HSA-5621481
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ub-specific processing proteases R-HSA-5689880
Hh mutants are degraded by ERAD R-HSA-5362768
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by WNT R-HSA-195721
Synthesis of DNA R-HSA-69239
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Host Interactions of HIV factors R-HSA-162909
Assembly of the pre-replicative complex R-HSA-68867
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 family signaling R-HSA-446652
Axon guidance R-HSA-422475
Cellular response to hypoxia R-HSA-1234174
DNA Replication R-HSA-69306
Stabilization of p53 R-HSA-69541
MAPK1/MAPK3 signaling R-HSA-5684996
PCP/CE pathway R-HSA-4086400
Cell Cycle, Mitotic R-HSA-69278
Vpu mediated degradation of CD4 R-HSA-180534
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Separation of Sister Chromatids R-HSA-2467813
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Apoptosis R-HSA-109581
TCF dependent signaling in response to WNT R-HSA-201681
G1/S Transition R-HSA-69206
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Vpu mediated degradation of CD4 R-HSA-180534
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
M Phase R-HSA-68886
Regulation of RAS by GAPs R-HSA-5658442
Orc1 removal from chromatin R-HSA-68949
Cytokine Signaling in Immune system R-HSA-1280215
Hedgehog 'on' state R-HSA-5632684
Degradation of DVL R-HSA-4641258
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Transcriptional regulation by RUNX3 R-HSA-8878159
MAPK family signaling cascades R-HSA-5683057
Defective CFTR causes cystic fibrosis R-HSA-5678895
Asymmetric localization of PCP proteins R-HSA-4608870
Cell Cycle Checkpoints R-HSA-69620
Mitotic G2-G2/M phases R-HSA-453274
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G1/S DNA Damage Checkpoints R-HSA-69615
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of mitotic cell cycle R-HSA-453276
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of Apoptosis R-HSA-169911
RNA Polymerase II Transcription R-HSA-73857
Interleukin-1 family signaling R-HSA-446652
Hedgehog ligand biogenesis R-HSA-5358346
Cellular responses to stimuli R-HSA-8953897
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to hypoxia R-HSA-1234174
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
DNA Replication Pre-Initiation R-HSA-69002
DNA Replication R-HSA-69306
Metabolism of RNA R-HSA-8953854
Regulation of RUNX3 expression and activity R-HSA-8941858
p53-Independent DNA Damage Response R-HSA-69610
FCERI mediated NF-kB activation R-HSA-2871837
Beta-catenin independent WNT signaling R-HSA-3858494
Signal Transduction R-HSA-162582
Signaling by NOTCH4 R-HSA-9013694
Infectious disease R-HSA-5663205
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Metabolism of amino acids and derivatives R-HSA-71291
G2/M Checkpoints R-HSA-69481
Signaling by ROBO receptors R-HSA-376176
Signaling by Interleukins R-HSA-449147
Signaling by WNT R-HSA-195721
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of AXIN R-HSA-4641257
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Post-translational protein modification R-HSA-597592
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
HIV Infection R-HSA-162906
ER-Phagosome pathway R-HSA-1236974
Signaling by NOTCH R-HSA-157118
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Transport of small molecules R-HSA-382551
Mitotic Metaphase and Anaphase R-HSA-2555396
Interleukin-1 signaling R-HSA-9020702
CLEC7A (Dectin-1) signaling R-HSA-5607764
Nervous system development R-HSA-9675108
Gene expression (Transcription) R-HSA-74160
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hh mutants are degraded by ERAD R-HSA-5362768
ABC transporter disorders R-HSA-5619084
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PCP/CE pathway R-HSA-4086400
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX1 R-HSA-8878171
Metabolism R-HSA-1430728
Metabolism of proteins R-HSA-392499
NIK-->noncanonical NF-kB signaling R-HSA-5676590
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Class I MHC mediated antigen processing & presentation R-HSA-983169
S Phase R-HSA-69242
MAPK1/MAPK3 signaling R-HSA-5684996
Axon guidance R-HSA-422475
Intracellular signaling by second messengers R-HSA-9006925
Degradation of GLI1 by the proteasome R-HSA-5610780
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Deubiquitination R-HSA-5688426
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Adaptive Immune System R-HSA-1280218
Cellular response to chemical stress R-HSA-9711123
Cell Cycle R-HSA-1640170
MAPK6/MAPK4 signaling R-HSA-5687128
PIP3 activates AKT signaling R-HSA-1257604
Assembly of the pre-replicative complex R-HSA-68867
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Downstream TCR signaling R-HSA-202424
Cellular responses to stress R-HSA-2262752
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Ub-specific processing proteases R-HSA-5689880
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Generic Transcription Pathway R-HSA-212436
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Synthesis of DNA R-HSA-69239
Programmed Cell Death R-HSA-5357801
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of polyamines R-HSA-351202
Hedgehog 'off' state R-HSA-5610787
Disease R-HSA-1643685
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Cyclin E associated events during G1/S transition R-HSA-69202
Negative regulation of NOTCH4 signaling R-HSA-9604323
TCR signaling R-HSA-202403
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Separation of Sister Chromatids R-HSA-2467813
ABC-family proteins mediated transport R-HSA-382556
Antigen processing-Cross presentation R-HSA-1236975
Regulation of PTEN stability and activity R-HSA-8948751
Degradation of GLI2 by the proteasome R-HSA-5610783
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cell Cycle, Mitotic R-HSA-69278
Stabilization of p53 R-HSA-69541
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hh mutants abrogate ligand secretion R-HSA-5387390
Neddylation R-HSA-8951664
RAF/MAP kinase cascade R-HSA-5673001
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Host Interactions of HIV factors R-HSA-162909
G2/M Transition R-HSA-69275
Mitotic Anaphase R-HSA-68882
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
PTEN Regulation R-HSA-6807070
C-type lectin receptors (CLRs) R-HSA-5621481
UCH proteinases R-HSA-5689603
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Vif-mediated degradation of APOBEC3G R-HSA-180585
Switching of origins to a post-replicative state R-HSA-69052
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Developmental Biology R-HSA-1266738
Mitotic G1 phase and G1/S transition R-HSA-453279
KEAP1-NFE2L2 pathway R-HSA-9755511

Expression Atlas ENSG00000100804
NCBI gene (formerly Entrezgene) 5693
GeneCards 9542
HGNC Symbol HGNC:9542
MIM gene 600306
UniProtKB Gene Name P28074
WikiGene 5693
Gene: PSMB11
Ensembl ID : ENSG00000222028
Description: proteasome subunit beta 11
Gene Synonyms: BETA5T
6 APIs:
228 Possible Orthologues:

Cytokine Signaling in Immune system R-HSA-1280215
TCR signaling R-HSA-202403
Signaling by Interleukins R-HSA-449147
Programmed Cell Death R-HSA-5357801
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
G2/M Transition R-HSA-69275
Metabolism of proteins R-HSA-392499
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism R-HSA-1430728
ER-Phagosome pathway R-HSA-1236974
ABC transporter disorders R-HSA-5619084
S Phase R-HSA-69242
Hedgehog 'off' state R-HSA-5610787
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of polyamines R-HSA-351202
Separation of Sister Chromatids R-HSA-2467813
MAPK family signaling cascades R-HSA-5683057
Hedgehog ligand biogenesis R-HSA-5358346
NIK-->noncanonical NF-kB signaling R-HSA-5676590
UCH proteinases R-HSA-5689603
p53-Independent DNA Damage Response R-HSA-69610
ABC-family proteins mediated transport R-HSA-382556
Innate Immune System R-HSA-168249
Regulation of mitotic cell cycle R-HSA-453276
Deubiquitination R-HSA-5688426
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
MAPK1/MAPK3 signaling R-HSA-5684996
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Mitotic G2-G2/M phases R-HSA-453274
Immune System R-HSA-168256
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PTEN Regulation R-HSA-6807070
Stabilization of p53 R-HSA-69541
Metabolism of amino acids and derivatives R-HSA-71291
Cell Cycle Checkpoints R-HSA-69620
Cellular responses to stimuli R-HSA-8953897
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Transcriptional regulation by RUNX2 R-HSA-8878166
Post-translational protein modification R-HSA-597592
Signaling by ROBO receptors R-HSA-376176
Degradation of GLI2 by the proteasome R-HSA-5610783
RAF/MAP kinase cascade R-HSA-5673001
Degradation of AXIN R-HSA-4641257
Axon guidance R-HSA-422475
Regulation of RAS by GAPs R-HSA-5658442
Cell Cycle, Mitotic R-HSA-69278
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Dependent G1 DNA Damage Response R-HSA-69563
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Switching of origins to a post-replicative state R-HSA-69052
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hedgehog 'on' state R-HSA-5632684
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of DVL R-HSA-4641258
Cell Cycle R-HSA-1640170
Mitotic Anaphase R-HSA-68882
Cellular response to chemical stress R-HSA-9711123
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signal Transduction R-HSA-162582
Disorders of transmembrane transporters R-HSA-5619115
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
HIV Infection R-HSA-162906
Hh mutants are degraded by ERAD R-HSA-5362768
Neddylation R-HSA-8951664
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of NF-kappaB in B cells R-HSA-1169091
Ub-specific processing proteases R-HSA-5689880
Synthesis of DNA R-HSA-69239
Transport of small molecules R-HSA-382551
Host Interactions of HIV factors R-HSA-162909
Interleukin-1 signaling R-HSA-9020702
Downstream TCR signaling R-HSA-202424
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Gene expression (Transcription) R-HSA-74160
Metabolism of RNA R-HSA-8953854
Regulation of Apoptosis R-HSA-169911
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of GLI1 by the proteasome R-HSA-5610780
Antigen processing-Cross presentation R-HSA-1236975
Signaling by WNT R-HSA-195721
Generic Transcription Pathway R-HSA-212436
Adaptive Immune System R-HSA-1280218
Regulation of RUNX2 expression and activity R-HSA-8939902
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of PTEN stability and activity R-HSA-8948751
Infectious disease R-HSA-5663205
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Vpu mediated degradation of CD4 R-HSA-180534
G2/M Checkpoints R-HSA-69481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
M Phase R-HSA-68886
PCP/CE pathway R-HSA-4086400
C-type lectin receptors (CLRs) R-HSA-5621481
Apoptosis R-HSA-109581
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hh mutants abrogate ligand secretion R-HSA-5387390
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Defective CFTR causes cystic fibrosis R-HSA-5678895
Disease R-HSA-1643685
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX1 R-HSA-8878171
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of beta-catenin by the destruction complex R-HSA-195253
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cytokine Signaling in Immune system R-HSA-1280215
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Interleukin-1 family signaling R-HSA-446652
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated NF-kB activation R-HSA-2871837
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
G1/S DNA Damage Checkpoints R-HSA-69615
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular response to hypoxia R-HSA-1234174
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by Hedgehog R-HSA-5358351
Separation of Sister Chromatids R-HSA-2467813
Metabolism of RNA R-HSA-8953854
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Adaptive Immune System R-HSA-1280218
Infectious disease R-HSA-5663205
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
TCR signaling R-HSA-202403
FCERI mediated NF-kB activation R-HSA-2871837
Metabolism R-HSA-1430728
Programmed Cell Death R-HSA-5357801
Regulation of expression of SLITs and ROBOs R-HSA-9010553
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Degradation of AXIN R-HSA-4641257
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by ROBO receptors R-HSA-376176
UCH proteinases R-HSA-5689603
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular response to chemical stress R-HSA-9711123
Antigen processing-Cross presentation R-HSA-1236975
Switching of origins to a post-replicative state R-HSA-69052
Metabolism of polyamines R-HSA-351202
Gene expression (Transcription) R-HSA-74160
Mitotic G2-G2/M phases R-HSA-453274
Beta-catenin independent WNT signaling R-HSA-3858494
ER-Phagosome pathway R-HSA-1236974
Hedgehog ligand biogenesis R-HSA-5358346
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of GLI1 by the proteasome R-HSA-5610780
Apoptosis R-HSA-109581
ABC-family proteins mediated transport R-HSA-382556
MAPK family signaling cascades R-HSA-5683057
Post-translational protein modification R-HSA-597592
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of Apoptosis R-HSA-169911
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nervous system development R-HSA-9675108
S Phase R-HSA-69242
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by Hedgehog R-HSA-5358351
G2/M Checkpoints R-HSA-69481
Interleukin-1 signaling R-HSA-9020702
Signaling by WNT R-HSA-195721
Degradation of beta-catenin by the destruction complex R-HSA-195253
KEAP1-NFE2L2 pathway R-HSA-9755511
Synthesis of DNA R-HSA-69239
Mitotic Anaphase R-HSA-68882
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX1 R-HSA-8878171
CLEC7A (Dectin-1) signaling R-HSA-5607764
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular responses to stimuli R-HSA-8953897
Innate Immune System R-HSA-168249
Disease R-HSA-1643685
Stabilization of p53 R-HSA-69541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
HIV Infection R-HSA-162906
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of GLI2 by the proteasome R-HSA-5610783
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vif-mediated degradation of APOBEC3G R-HSA-180585
Metabolism of amino acids and derivatives R-HSA-71291
Neddylation R-HSA-8951664
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX2 R-HSA-8878166
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
G1/S DNA Damage Checkpoints R-HSA-69615
DNA Replication R-HSA-69306
RAF/MAP kinase cascade R-HSA-5673001
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Orc1 removal from chromatin R-HSA-68949
Deubiquitination R-HSA-5688426
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Transition R-HSA-69275
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Transport of small molecules R-HSA-382551
M Phase R-HSA-68886
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream TCR signaling R-HSA-202424
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of DVL R-HSA-4641258
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of mitotic cell cycle R-HSA-453276
Interleukin-1 family signaling R-HSA-446652
Regulation of RAS by GAPs R-HSA-5658442
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Host Interactions of HIV factors R-HSA-162909
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
RNA Polymerase II Transcription R-HSA-73857
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Axon guidance R-HSA-422475
PIP3 activates AKT signaling R-HSA-1257604
Activation of NF-kappaB in B cells R-HSA-1169091
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Mitotic Metaphase and Anaphase R-HSA-2555396
Class I MHC mediated antigen processing & presentation R-HSA-983169
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
PTEN Regulation R-HSA-6807070
C-type lectin receptors (CLRs) R-HSA-5621481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of proteins R-HSA-392499
Hh mutants are degraded by ERAD R-HSA-5362768
MAPK6/MAPK4 signaling R-HSA-5687128
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Independent DNA Damage Response R-HSA-69610
Signaling by Interleukins R-HSA-449147
PCP/CE pathway R-HSA-4086400
Immune System R-HSA-168256
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle Checkpoints R-HSA-69620
ABC transporter disorders R-HSA-5619084
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signal Transduction R-HSA-162582
Cell Cycle, Mitotic R-HSA-69278
Intracellular signaling by second messengers R-HSA-9006925
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hedgehog 'on' state R-HSA-5632684
Disorders of transmembrane transporters R-HSA-5619115
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cellular response to hypoxia R-HSA-1234174
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of amino acids and derivatives R-HSA-71291
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cell Cycle Checkpoints R-HSA-69620
NIK-->noncanonical NF-kB signaling R-HSA-5676590
C-type lectin receptors (CLRs) R-HSA-5621481
Mitotic G2-G2/M phases R-HSA-453274
Immune System R-HSA-168256
Hh mutants abrogate ligand secretion R-HSA-5387390
ABC-family proteins mediated transport R-HSA-382556
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Axon guidance R-HSA-422475
TCR signaling R-HSA-202403
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transport of small molecules R-HSA-382551
Metabolism R-HSA-1430728
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RAS by GAPs R-HSA-5658442
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog 'off' state R-HSA-5610787
Hh mutants are degraded by ERAD R-HSA-5362768
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CLEC7A (Dectin-1) signaling R-HSA-5607764
Intracellular signaling by second messengers R-HSA-9006925
Separation of Sister Chromatids R-HSA-2467813
Neddylation R-HSA-8951664
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Interleukins R-HSA-449147
Stabilization of p53 R-HSA-69541
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cellular responses to stress R-HSA-2262752
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular response to hypoxia R-HSA-1234174
Degradation of GLI1 by the proteasome R-HSA-5610780
MAPK6/MAPK4 signaling R-HSA-5687128
Activation of NF-kappaB in B cells R-HSA-1169091
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Gene expression (Transcription) R-HSA-74160
Degradation of GLI2 by the proteasome R-HSA-5610783
Cell Cycle, Mitotic R-HSA-69278
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signal Transduction R-HSA-162582
Adaptive Immune System R-HSA-1280218
Vif-mediated degradation of APOBEC3G R-HSA-180585
Nervous system development R-HSA-9675108
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
S Phase R-HSA-69242
Mitotic Metaphase and Anaphase R-HSA-2555396
Post-translational protein modification R-HSA-597592
HIV Infection R-HSA-162906
Apoptosis R-HSA-109581
G1/S DNA Damage Checkpoints R-HSA-69615
Ub-specific processing proteases R-HSA-5689880
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Deubiquitination R-HSA-5688426
Vpu mediated degradation of CD4 R-HSA-180534
KEAP1-NFE2L2 pathway R-HSA-9755511
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Interleukin-1 signaling R-HSA-9020702
Developmental Biology R-HSA-1266738
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Innate Immune System R-HSA-168249
Hedgehog ligand biogenesis R-HSA-5358346
Switching of origins to a post-replicative state R-HSA-69052
G2/M Checkpoints R-HSA-69481
Programmed Cell Death R-HSA-5357801
Cellular responses to stimuli R-HSA-8953897
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PIP3 activates AKT signaling R-HSA-1257604
FCERI mediated NF-kB activation R-HSA-2871837
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of Apoptosis R-HSA-169911
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of mitotic cell cycle R-HSA-453276
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
M Phase R-HSA-68886
Interleukin-1 family signaling R-HSA-446652
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX1 R-HSA-8878171
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disorders of transmembrane transporters R-HSA-5619115
Host Interactions of HIV factors R-HSA-162909
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by WNT R-HSA-195721
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Independent DNA Damage Response R-HSA-69610
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog 'on' state R-HSA-5632684
Metabolism of proteins R-HSA-392499
Cellular response to chemical stress R-HSA-9711123
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by ROBO receptors R-HSA-376176
Orc1 removal from chromatin R-HSA-68949
ABC transporter disorders R-HSA-5619084
Regulation of RUNX2 expression and activity R-HSA-8939902
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
RNA Polymerase II Transcription R-HSA-73857
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Infectious disease R-HSA-5663205
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
DNA Replication R-HSA-69306
Synthesis of DNA R-HSA-69239
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
UCH proteinases R-HSA-5689603
Asymmetric localization of PCP proteins R-HSA-4608870
Antigen processing-Cross presentation R-HSA-1236975
Degradation of AXIN R-HSA-4641257
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
MAPK family signaling cascades R-HSA-5683057
PTEN Regulation R-HSA-6807070
Cell Cycle R-HSA-1640170
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of polyamines R-HSA-351202
ER-Phagosome pathway R-HSA-1236974
Downstream TCR signaling R-HSA-202424
Mitotic Anaphase R-HSA-68882
Degradation of DVL R-HSA-4641258
Transcriptional regulation by RUNX2 R-HSA-8878166
Disease R-HSA-1643685
PCP/CE pathway R-HSA-4086400
G2/M Transition R-HSA-69275
Innate Immune System R-HSA-168249
G2/M Checkpoints R-HSA-69481
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of mitotic cell cycle R-HSA-453276
PIP3 activates AKT signaling R-HSA-1257604
Nervous system development R-HSA-9675108
Metabolism R-HSA-1430728
Deubiquitination R-HSA-5688426
Hh mutants are degraded by ERAD R-HSA-5362768
G1/S DNA Damage Checkpoints R-HSA-69615
Neddylation R-HSA-8951664
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Defective CFTR causes cystic fibrosis R-HSA-5678895
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
G2/M Transition R-HSA-69275
Cellular response to hypoxia R-HSA-1234174
KEAP1-NFE2L2 pathway R-HSA-9755511
Hedgehog 'on' state R-HSA-5632684
Asymmetric localization of PCP proteins R-HSA-4608870
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of amino acids and derivatives R-HSA-71291
Immune System R-HSA-168256
Post-translational protein modification R-HSA-597592
RNA Polymerase II Transcription R-HSA-73857
ABC transporter disorders R-HSA-5619084
Hedgehog 'off' state R-HSA-5610787
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
M Phase R-HSA-68886
Switching of origins to a post-replicative state R-HSA-69052
Ub-specific processing proteases R-HSA-5689880
RAF/MAP kinase cascade R-HSA-5673001
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cellular response to chemical stress R-HSA-9711123
Signaling by Hedgehog R-HSA-5358351
Interleukin-1 family signaling R-HSA-446652
Cell Cycle, Mitotic R-HSA-69278
Degradation of AXIN R-HSA-4641257
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of expression of SLITs and ROBOs R-HSA-9010553
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Adaptive Immune System R-HSA-1280218
Signaling by Interleukins R-HSA-449147
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by WNT R-HSA-195721
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Separation of Sister Chromatids R-HSA-2467813
Orc1 removal from chromatin R-HSA-68949
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by ROBO receptors R-HSA-376176
Regulation of RUNX2 expression and activity R-HSA-8939902
Disease R-HSA-1643685
Metabolism of polyamines R-HSA-351202
Mitotic G2-G2/M phases R-HSA-453274
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
DNA Replication R-HSA-69306
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
PTEN Regulation R-HSA-6807070
Cellular responses to stress R-HSA-2262752
PCP/CE pathway R-HSA-4086400
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
Interleukin-1 signaling R-HSA-9020702
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
p53-Independent DNA Damage Response R-HSA-69610
ABC-family proteins mediated transport R-HSA-382556
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of proteins R-HSA-392499
HIV Infection R-HSA-162906
Apoptosis R-HSA-109581
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK family signaling cascades R-HSA-5683057
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Vif-mediated degradation of APOBEC3G R-HSA-180585
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing-Cross presentation R-HSA-1236975
Degradation of DVL R-HSA-4641258
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transport of small molecules R-HSA-382551
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of GLI2 by the proteasome R-HSA-5610783
CLEC7A (Dectin-1) signaling R-HSA-5607764
Developmental Biology R-HSA-1266738
S Phase R-HSA-69242
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of Apoptosis R-HSA-169911
TCR signaling R-HSA-202403
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI1 by the proteasome R-HSA-5610780
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Infectious disease R-HSA-5663205
Vpu mediated degradation of CD4 R-HSA-180534
Cell Cycle R-HSA-1640170
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Beta-catenin independent WNT signaling R-HSA-3858494
Activation of NF-kappaB in B cells R-HSA-1169091
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cytokine Signaling in Immune system R-HSA-1280215
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular responses to stimuli R-HSA-8953897
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle Checkpoints R-HSA-69620
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Synthesis of DNA R-HSA-69239
Axon guidance R-HSA-422475
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Programmed Cell Death R-HSA-5357801
Stabilization of p53 R-HSA-69541
UCH proteinases R-HSA-5689603
Class I MHC mediated antigen processing & presentation R-HSA-983169
Host Interactions of HIV factors R-HSA-162909
Downstream TCR signaling R-HSA-202424
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX1 R-HSA-8878171
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Checkpoints R-HSA-69481
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cellular responses to stress R-HSA-2262752
Synthesis of DNA R-HSA-69239
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
MAPK6/MAPK4 signaling R-HSA-5687128
Generic Transcription Pathway R-HSA-212436
M Phase R-HSA-68886
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'off' state R-HSA-5610787
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Defective CFTR causes cystic fibrosis R-HSA-5678895
Switching of origins to a post-replicative state R-HSA-69052
Asymmetric localization of PCP proteins R-HSA-4608870
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing-Cross presentation R-HSA-1236975
TCR signaling R-HSA-202403
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Ub-specific processing proteases R-HSA-5689880
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism of polyamines R-HSA-351202
Signaling by ROBO receptors R-HSA-376176
Vif-mediated degradation of APOBEC3G R-HSA-180585
Immune System R-HSA-168256
Signaling by Hedgehog R-HSA-5358351
RAF/MAP kinase cascade R-HSA-5673001
Post-translational protein modification R-HSA-597592
Metabolism of RNA R-HSA-8953854
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Developmental Biology R-HSA-1266738
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Disease R-HSA-1643685
Degradation of DVL R-HSA-4641258
Adaptive Immune System R-HSA-1280218
Cell Cycle, Mitotic R-HSA-69278
Signaling by WNT R-HSA-195721
Metabolism of amino acids and derivatives R-HSA-71291
G2/M Transition R-HSA-69275
PIP3 activates AKT signaling R-HSA-1257604
Apoptosis R-HSA-109581
ER-Phagosome pathway R-HSA-1236974
KEAP1-NFE2L2 pathway R-HSA-9755511
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 family signaling R-HSA-446652
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stimuli R-HSA-8953897
Disorders of transmembrane transporters R-HSA-5619115
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of GLI2 by the proteasome R-HSA-5610783
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
UCH proteinases R-HSA-5689603
S Phase R-HSA-69242
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Deubiquitination R-HSA-5688426
CLEC7A (Dectin-1) signaling R-HSA-5607764
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Separation of Sister Chromatids R-HSA-2467813
Transport of small molecules R-HSA-382551
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Host Interactions of HIV factors R-HSA-162909
Cell Cycle Checkpoints R-HSA-69620
RNA Polymerase II Transcription R-HSA-73857
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PCP/CE pathway R-HSA-4086400
Downstream TCR signaling R-HSA-202424
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK family signaling cascades R-HSA-5683057
Hedgehog ligand biogenesis R-HSA-5358346
Interleukin-1 signaling R-HSA-9020702
Hh mutants abrogate ligand secretion R-HSA-5387390
TCF dependent signaling in response to WNT R-HSA-201681
Infectious disease R-HSA-5663205
Degradation of AXIN R-HSA-4641257
ABC-family proteins mediated transport R-HSA-382556
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Anaphase R-HSA-68882
ABC transporter disorders R-HSA-5619084
Orc1 removal from chromatin R-HSA-68949
Cell Cycle R-HSA-1640170
Metabolism R-HSA-1430728
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
PTEN Regulation R-HSA-6807070
Hedgehog 'on' state R-HSA-5632684
Innate Immune System R-HSA-168249
G1/S DNA Damage Checkpoints R-HSA-69615
DNA Replication R-HSA-69306
Signaling by Interleukins R-HSA-449147
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Mitotic Metaphase and Anaphase R-HSA-2555396
Neddylation R-HSA-8951664
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX2 R-HSA-8878166
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular response to hypoxia R-HSA-1234174
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Mitotic G2-G2/M phases R-HSA-453274
Axon guidance R-HSA-422475
Regulation of Apoptosis R-HSA-169911
Programmed Cell Death R-HSA-5357801
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK1/MAPK3 signaling R-HSA-5684996
Intracellular signaling by second messengers R-HSA-9006925
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Stabilization of p53 R-HSA-69541
C-type lectin receptors (CLRs) R-HSA-5621481
HIV Infection R-HSA-162906
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
FCERI mediated NF-kB activation R-HSA-2871837
MAPK family signaling cascades R-HSA-5683057
Metabolism of amino acids and derivatives R-HSA-71291
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Ub-specific processing proteases R-HSA-5689880
ABC-family proteins mediated transport R-HSA-382556
MAPK1/MAPK3 signaling R-HSA-5684996
G2/M Transition R-HSA-69275
Downstream TCR signaling R-HSA-202424
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Vif-mediated degradation of APOBEC3G R-HSA-180585
CLEC7A (Dectin-1) signaling R-HSA-5607764
ER-Phagosome pathway R-HSA-1236974
Cell Cycle R-HSA-1640170
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle, Mitotic R-HSA-69278
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Infectious disease R-HSA-5663205
Asymmetric localization of PCP proteins R-HSA-4608870
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of RAS by GAPs R-HSA-5658442
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Orc1 removal from chromatin R-HSA-68949
Metabolism R-HSA-1430728
p53-Dependent G1 DNA Damage Response R-HSA-69563
Programmed Cell Death R-HSA-5357801
RAF/MAP kinase cascade R-HSA-5673001
Generic Transcription Pathway R-HSA-212436
HIV Infection R-HSA-162906
Regulation of PTEN stability and activity R-HSA-8948751
Host Interactions of HIV factors R-HSA-162909
C-type lectin receptors (CLRs) R-HSA-5621481
Signal Transduction R-HSA-162582
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 signaling R-HSA-9020702
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
RNA Polymerase II Transcription R-HSA-73857
Degradation of GLI1 by the proteasome R-HSA-5610780
UCH proteinases R-HSA-5689603
Gene expression (Transcription) R-HSA-74160
Hedgehog ligand biogenesis R-HSA-5358346
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of RNA R-HSA-8953854
Degradation of DVL R-HSA-4641258
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism of polyamines R-HSA-351202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of proteins R-HSA-392499
S Phase R-HSA-69242
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hedgehog 'on' state R-HSA-5632684
Intracellular signaling by second messengers R-HSA-9006925
Regulation of mitotic cell cycle R-HSA-453276
PIP3 activates AKT signaling R-HSA-1257604
Transport of small molecules R-HSA-382551
Regulation of RUNX2 expression and activity R-HSA-8939902
Post-translational protein modification R-HSA-597592
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TCR signaling R-HSA-202403
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic G2-G2/M phases R-HSA-453274
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Immune System R-HSA-168256
Signaling by WNT R-HSA-195721
FCERI mediated NF-kB activation R-HSA-2871837
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PCP/CE pathway R-HSA-4086400
Degradation of GLI2 by the proteasome R-HSA-5610783
Apoptosis R-HSA-109581
Neddylation R-HSA-8951664
PTEN Regulation R-HSA-6807070
Vpu mediated degradation of CD4 R-HSA-180534
p53-Independent DNA Damage Response R-HSA-69610
Signaling by Interleukins R-HSA-449147
Beta-catenin independent WNT signaling R-HSA-3858494
Hh mutants abrogate ligand secretion R-HSA-5387390
Adaptive Immune System R-HSA-1280218
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G2/M Checkpoints R-HSA-69481
Disease R-HSA-1643685
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Switching of origins to a post-replicative state R-HSA-69052
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Stabilization of p53 R-HSA-69541
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Disorders of transmembrane transporters R-HSA-5619115
Cellular responses to stimuli R-HSA-8953897
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Transcriptional regulation by RUNX2 R-HSA-8878166
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of AXIN R-HSA-4641257
Separation of Sister Chromatids R-HSA-2467813
Nervous system development R-HSA-9675108
Interleukin-1 family signaling R-HSA-446652
M Phase R-HSA-68886
Signaling by ROBO receptors R-HSA-376176
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ABC transporter disorders R-HSA-5619084
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by Hedgehog R-HSA-5358351
Synthesis of DNA R-HSA-69239
Cellular response to chemical stress R-HSA-9711123
Regulation of Apoptosis R-HSA-169911
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Innate Immune System R-HSA-168249
Degradation of beta-catenin by the destruction complex R-HSA-195253
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Mitotic Anaphase R-HSA-68882
Antigen processing-Cross presentation R-HSA-1236975
Axon guidance R-HSA-422475
Cytokine Signaling in Immune system R-HSA-1280215
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle Checkpoints R-HSA-69620
Cellular response to hypoxia R-HSA-1234174
Deubiquitination R-HSA-5688426
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hedgehog 'off' state R-HSA-5610787
Neddylation R-HSA-8951664
KEAP1-NFE2L2 pathway R-HSA-9755511
RAF/MAP kinase cascade R-HSA-5673001
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Antigen processing-Cross presentation R-HSA-1236975
G2/M Transition R-HSA-69275
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Anaphase R-HSA-68882
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
MAPK family signaling cascades R-HSA-5683057
G1/S DNA Damage Checkpoints R-HSA-69615
Ub-specific processing proteases R-HSA-5689880
Hh mutants abrogate ligand secretion R-HSA-5387390
Asymmetric localization of PCP proteins R-HSA-4608870
Switching of origins to a post-replicative state R-HSA-69052
HIV Infection R-HSA-162906
Hedgehog ligand biogenesis R-HSA-5358346
Hedgehog 'off' state R-HSA-5610787
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Orc1 removal from chromatin R-HSA-68949
Interleukin-1 family signaling R-HSA-446652
FCERI mediated NF-kB activation R-HSA-2871837
ER-Phagosome pathway R-HSA-1236974
Regulation of mitotic cell cycle R-HSA-453276
Disease R-HSA-1643685
Cell Cycle, Mitotic R-HSA-69278
UCH proteinases R-HSA-5689603
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Separation of Sister Chromatids R-HSA-2467813
Host Interactions of HIV factors R-HSA-162909
CLEC7A (Dectin-1) signaling R-HSA-5607764
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
Disorders of transmembrane transporters R-HSA-5619115
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Hedgehog R-HSA-5358351
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Post-translational protein modification R-HSA-597592
Interleukin-1 signaling R-HSA-9020702
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
M Phase R-HSA-68886
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of RUNX2 expression and activity R-HSA-8939902
Intracellular signaling by second messengers R-HSA-9006925
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transport of small molecules R-HSA-382551
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCF dependent signaling in response to WNT R-HSA-201681
RNA Polymerase II Transcription R-HSA-73857
Vpu mediated degradation of CD4 R-HSA-180534
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PTEN Regulation R-HSA-6807070
Downstream TCR signaling R-HSA-202424
ABC transporter disorders R-HSA-5619084
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RAS by GAPs R-HSA-5658442
Adaptive Immune System R-HSA-1280218
Degradation of AXIN R-HSA-4641257
p53-Independent DNA Damage Response R-HSA-69610
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by Interleukins R-HSA-449147
PCP/CE pathway R-HSA-4086400
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Developmental Biology R-HSA-1266738
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hh mutants are degraded by ERAD R-HSA-5362768
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cellular responses to stimuli R-HSA-8953897
Deubiquitination R-HSA-5688426
Metabolism of polyamines R-HSA-351202
Gene expression (Transcription) R-HSA-74160
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism R-HSA-1430728
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
Stabilization of p53 R-HSA-69541
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of GLI2 by the proteasome R-HSA-5610783
DNA Replication R-HSA-69306
Mitotic Metaphase and Anaphase R-HSA-2555396
TCR signaling R-HSA-202403
Degradation of beta-catenin by the destruction complex R-HSA-195253
Vif-mediated degradation of APOBEC3G R-HSA-180585
S Phase R-HSA-69242
Apoptosis R-HSA-109581
Cellular response to chemical stress R-HSA-9711123
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cell Cycle Checkpoints R-HSA-69620
Signal Transduction R-HSA-162582
Hedgehog 'on' state R-HSA-5632684
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of Apoptosis R-HSA-169911
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Programmed Cell Death R-HSA-5357801
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Transcriptional regulation by RUNX1 R-HSA-8878171
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of RNA R-HSA-8953854
Cellular response to hypoxia R-HSA-1234174
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of DVL R-HSA-4641258
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
C-type lectin receptors (CLRs) R-HSA-5621481
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
ABC-family proteins mediated transport R-HSA-382556
Cellular responses to stress R-HSA-2262752
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Infectious disease R-HSA-5663205
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
NIK-->noncanonical NF-kB signaling R-HSA-5676590
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Synthesis of DNA R-HSA-69239
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by WNT R-HSA-195721
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Immune System R-HSA-168256
Axon guidance R-HSA-422475
Signaling by ROBO receptors R-HSA-376176
Degradation of GLI1 by the proteasome R-HSA-5610780
Beta-catenin independent WNT signaling R-HSA-3858494
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Nervous system development R-HSA-9675108
G2/M Checkpoints R-HSA-69481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Innate Immune System R-HSA-168249
TCF dependent signaling in response to WNT R-HSA-201681
RAF/MAP kinase cascade R-HSA-5673001
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cytokine Signaling in Immune system R-HSA-1280215
Beta-catenin independent WNT signaling R-HSA-3858494
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
Cellular responses to stimuli R-HSA-8953897
MAPK family signaling cascades R-HSA-5683057
Asymmetric localization of PCP proteins R-HSA-4608870
Degradation of GLI1 by the proteasome R-HSA-5610780
Degradation of GLI2 by the proteasome R-HSA-5610783
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Immune System R-HSA-168256
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic Metaphase and Anaphase R-HSA-2555396
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Vpu mediated degradation of CD4 R-HSA-180534
G2/M Transition R-HSA-69275
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Intracellular signaling by second messengers R-HSA-9006925
G1/S DNA Damage Checkpoints R-HSA-69615
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RUNX2 expression and activity R-HSA-8939902
PIP3 activates AKT signaling R-HSA-1257604
Defective CFTR causes cystic fibrosis R-HSA-5678895
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
ABC-family proteins mediated transport R-HSA-382556
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hh mutants are degraded by ERAD R-HSA-5362768
Metabolism of amino acids and derivatives R-HSA-71291
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
HIV Infection R-HSA-162906
Signal Transduction R-HSA-162582
Adaptive Immune System R-HSA-1280218
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Innate Immune System R-HSA-168249
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G2-G2/M phases R-HSA-453274
M Phase R-HSA-68886
Stabilization of p53 R-HSA-69541
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by Interleukins R-HSA-449147
Metabolism of RNA R-HSA-8953854
ER-Phagosome pathway R-HSA-1236974
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cell Cycle R-HSA-1640170
Signaling by ROBO receptors R-HSA-376176
Signaling by WNT R-HSA-195721
MAPK6/MAPK4 signaling R-HSA-5687128
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transport of small molecules R-HSA-382551
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of proteins R-HSA-392499
Generic Transcription Pathway R-HSA-212436
Metabolism of polyamines R-HSA-351202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog 'on' state R-HSA-5632684
Deubiquitination R-HSA-5688426
Host Interactions of HIV factors R-HSA-162909
Downstream TCR signaling R-HSA-202424
Post-translational protein modification R-HSA-597592
TCR signaling R-HSA-202403
Developmental Biology R-HSA-1266738
Cellular response to hypoxia R-HSA-1234174
Mitotic Anaphase R-HSA-68882
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of AXIN R-HSA-4641257
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
p53-Independent DNA Damage Response R-HSA-69610
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ub-specific processing proteases R-HSA-5689880
Regulation of mitotic cell cycle R-HSA-453276
Separation of Sister Chromatids R-HSA-2467813
Interleukin-1 signaling R-HSA-9020702
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Disease R-HSA-1643685
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK1/MAPK3 signaling R-HSA-5684996
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of DVL R-HSA-4641258
Metabolism R-HSA-1430728
RNA Polymerase II Transcription R-HSA-73857
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Interleukin-1 family signaling R-HSA-446652
Hedgehog 'off' state R-HSA-5610787
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
S Phase R-HSA-69242
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
FCERI mediated NF-kB activation R-HSA-2871837
Transcriptional regulation by RUNX1 R-HSA-8878171
Disorders of transmembrane transporters R-HSA-5619115
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle, Mitotic R-HSA-69278
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cellular responses to stress R-HSA-2262752
Cell Cycle Checkpoints R-HSA-69620
DNA Replication R-HSA-69306
PCP/CE pathway R-HSA-4086400
Gene expression (Transcription) R-HSA-74160
Apoptosis R-HSA-109581
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX2 R-HSA-8878166
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Axon guidance R-HSA-422475
PTEN Regulation R-HSA-6807070
Neddylation R-HSA-8951664
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hh mutants abrogate ligand secretion R-HSA-5387390
Programmed Cell Death R-HSA-5357801
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Synthesis of DNA R-HSA-69239
ABC transporter disorders R-HSA-5619084
C-type lectin receptors (CLRs) R-HSA-5621481
Orc1 removal from chromatin R-HSA-68949
Regulation of Apoptosis R-HSA-169911
Cellular response to chemical stress R-HSA-9711123
Antigen processing-Cross presentation R-HSA-1236975
Switching of origins to a post-replicative state R-HSA-69052
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Hedgehog R-HSA-5358351
G2/M Checkpoints R-HSA-69481
G2/M Transition R-HSA-69275
Signaling by WNT R-HSA-195721
Metabolism of proteins R-HSA-392499
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
FCERI mediated NF-kB activation R-HSA-2871837
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing-Cross presentation R-HSA-1236975
Degradation of AXIN R-HSA-4641257
Switching of origins to a post-replicative state R-HSA-69052
MAPK6/MAPK4 signaling R-HSA-5687128
Immune System R-HSA-168256
Deubiquitination R-HSA-5688426
RAF/MAP kinase cascade R-HSA-5673001
Neddylation R-HSA-8951664
Regulation of Apoptosis R-HSA-169911
Defective CFTR causes cystic fibrosis R-HSA-5678895
UCH proteinases R-HSA-5689603
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Adaptive Immune System R-HSA-1280218
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Stabilization of p53 R-HSA-69541
Interleukin-1 signaling R-HSA-9020702
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
Regulation of RAS by GAPs R-HSA-5658442
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of mitotic cell cycle R-HSA-453276
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
TCF dependent signaling in response to WNT R-HSA-201681
Gene expression (Transcription) R-HSA-74160
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hedgehog 'on' state R-HSA-5632684
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by Interleukins R-HSA-449147
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Nervous system development R-HSA-9675108
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Apoptosis R-HSA-109581
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ub-specific processing proteases R-HSA-5689880
Degradation of GLI2 by the proteasome R-HSA-5610783
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Post-translational protein modification R-HSA-597592
Vif-mediated degradation of APOBEC3G R-HSA-180585
ABC transporter disorders R-HSA-5619084
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Downstream TCR signaling R-HSA-202424
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI1 by the proteasome R-HSA-5610780
G2/M Checkpoints R-HSA-69481
Metabolism R-HSA-1430728
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Class I MHC mediated antigen processing & presentation R-HSA-983169
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Host Interactions of HIV factors R-HSA-162909
Programmed Cell Death R-HSA-5357801
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Beta-catenin independent WNT signaling R-HSA-3858494
Transcriptional regulation by RUNX2 R-HSA-8878166
G1/S DNA Damage Checkpoints R-HSA-69615
Vpu mediated degradation of CD4 R-HSA-180534
Cellular responses to stimuli R-HSA-8953897
ER-Phagosome pathway R-HSA-1236974
Cell Cycle, Mitotic R-HSA-69278
RNA Polymerase II Transcription R-HSA-73857
Disorders of transmembrane transporters R-HSA-5619115
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Anaphase R-HSA-68882
Regulation of RUNX2 expression and activity R-HSA-8939902
CLEC7A (Dectin-1) signaling R-HSA-5607764
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
KEAP1-NFE2L2 pathway R-HSA-9755511
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by Hedgehog R-HSA-5358351
Hh mutants abrogate ligand secretion R-HSA-5387390
M Phase R-HSA-68886
PIP3 activates AKT signaling R-HSA-1257604
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PCP/CE pathway R-HSA-4086400
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cell Cycle R-HSA-1640170
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic G2-G2/M phases R-HSA-453274
Synthesis of DNA R-HSA-69239
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle Checkpoints R-HSA-69620
ABC-family proteins mediated transport R-HSA-382556
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of polyamines R-HSA-351202
Degradation of DVL R-HSA-4641258
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
C-type lectin receptors (CLRs) R-HSA-5621481
S Phase R-HSA-69242
Orc1 removal from chromatin R-HSA-68949
Signal Transduction R-HSA-162582
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX1 R-HSA-8878171
Axon guidance R-HSA-422475
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Infectious disease R-HSA-5663205
Regulation of PTEN stability and activity R-HSA-8948751
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Hedgehog ligand biogenesis R-HSA-5358346
Cellular response to chemical stress R-HSA-9711123
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Cellular response to hypoxia R-HSA-1234174
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by ROBO receptors R-HSA-376176
Mitotic Metaphase and Anaphase R-HSA-2555396
Interleukin-1 family signaling R-HSA-446652
Metabolism of RNA R-HSA-8953854
TCR signaling R-HSA-202403
Developmental Biology R-HSA-1266738
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
HIV Infection R-HSA-162906
PTEN Regulation R-HSA-6807070
DNA Replication R-HSA-69306
MAPK1/MAPK3 signaling R-HSA-5684996
Activation of NF-kappaB in B cells R-HSA-1169091
Hedgehog 'off' state R-HSA-5610787
Generic Transcription Pathway R-HSA-212436
Hh mutants are degraded by ERAD R-HSA-5362768

Expression Atlas ENSG00000222028
NCBI gene (formerly Entrezgene) 122706
GeneCards 31963
HGNC Symbol HGNC:31963
MIM gene 611137
UniProtKB Gene Name A5LHX3
WikiGene 122706
Gene: PSMB10
Ensembl ID : ENSG00000205220
Description: proteasome 20S subunit beta 10
Gene Synonyms: BETA2I,LMP10,MECL1,MGC1665
6 APIs:
172 Possible Orthologues:

CLEC7A (Dectin-1) signaling R-HSA-5607764
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Immune System R-HSA-168256
M Phase R-HSA-68886
Gene expression (Transcription) R-HSA-74160
S Phase R-HSA-69242
Adaptive Immune System R-HSA-1280218
Regulation of mitotic cell cycle R-HSA-453276
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cell Cycle R-HSA-1640170
Neddylation R-HSA-8951664
Signaling by Hedgehog R-HSA-5358351
Orc1 removal from chromatin R-HSA-68949
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cellular response to hypoxia R-HSA-1234174
Disorders of transmembrane transporters R-HSA-5619115
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cytokine Signaling in Immune system R-HSA-1280215
Nuclear events mediated by NFE2L2 R-HSA-9759194
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of proteins R-HSA-392499
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by WNT R-HSA-195721
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Innate Immune System R-HSA-168249
Nervous system development R-HSA-9675108
Cellular responses to stimuli R-HSA-8953897
C-type lectin receptors (CLRs) R-HSA-5621481
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Synthesis of DNA R-HSA-69239
Deubiquitination R-HSA-5688426
Generic Transcription Pathway R-HSA-212436
Switching of origins to a post-replicative state R-HSA-69052
Cellular responses to stress R-HSA-2262752
Degradation of DVL R-HSA-4641258
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Infectious disease R-HSA-5663205
Interleukin-1 signaling R-HSA-9020702
Degradation of AXIN R-HSA-4641257
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Vpu mediated degradation of CD4 R-HSA-180534
Cellular response to chemical stress R-HSA-9711123
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Checkpoints R-HSA-69481
G1/S DNA Damage Checkpoints R-HSA-69615
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Axon guidance R-HSA-422475
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Vif-mediated degradation of APOBEC3G R-HSA-180585
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
MAPK1/MAPK3 signaling R-HSA-5684996
RNA Polymerase II Transcription R-HSA-73857
Mitotic G1 phase and G1/S transition R-HSA-453279
PCP/CE pathway R-HSA-4086400
Mitotic G2-G2/M phases R-HSA-453274
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle Checkpoints R-HSA-69620
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by NOTCH R-HSA-157118
Disease R-HSA-1643685
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of Apoptosis R-HSA-169911
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX1 R-HSA-8878171
Downstream TCR signaling R-HSA-202424
Regulation of expression of SLITs and ROBOs R-HSA-9010553
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Beta-catenin independent WNT signaling R-HSA-3858494
Ub-specific processing proteases R-HSA-5689880
Regulation of RUNX2 expression and activity R-HSA-8939902
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hh mutants are degraded by ERAD R-HSA-5362768
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Separation of Sister Chromatids R-HSA-2467813
Metabolism of polyamines R-HSA-351202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Asymmetric localization of PCP proteins R-HSA-4608870
MAPK family signaling cascades R-HSA-5683057
Degradation of beta-catenin by the destruction complex R-HSA-195253
PTEN Regulation R-HSA-6807070
ER-Phagosome pathway R-HSA-1236974
Hedgehog 'off' state R-HSA-5610787
Regulation of RAS by GAPs R-HSA-5658442
Developmental Biology R-HSA-1266738
Regulation of PTEN stability and activity R-HSA-8948751
Activation of NF-kappaB in B cells R-HSA-1169091
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by ROBO receptors R-HSA-376176
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of GLI1 by the proteasome R-HSA-5610780
CLEC7A (Dectin-1) signaling R-HSA-5607764
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing-Cross presentation R-HSA-1236975
Hh mutants abrogate ligand secretion R-HSA-5387390
DNA Replication Pre-Initiation R-HSA-69002
Host Interactions of HIV factors R-HSA-162909
KEAP1-NFE2L2 pathway R-HSA-9755511
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Hedgehog ligand biogenesis R-HSA-5358346
p53-Independent DNA Damage Response R-HSA-69610
Signaling by Interleukins R-HSA-449147
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of GLI2 by the proteasome R-HSA-5610783
Apoptosis R-HSA-109581
Mitotic Anaphase R-HSA-68882
UCH proteinases R-HSA-5689603
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX2 R-HSA-8878166
TCF dependent signaling in response to WNT R-HSA-201681
Immune System R-HSA-168256
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cell Cycle, Mitotic R-HSA-69278
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX3 R-HSA-8878159
RAF/MAP kinase cascade R-HSA-5673001
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
ABC-family proteins mediated transport R-HSA-382556
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
ABC transporter disorders R-HSA-5619084
HIV Infection R-HSA-162906
Assembly of the pre-replicative complex R-HSA-68867
DNA Replication R-HSA-69306
Interleukin-1 family signaling R-HSA-446652
G2/M Transition R-HSA-69275
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G1/S Transition R-HSA-69206
Metabolism of RNA R-HSA-8953854
Hedgehog 'on' state R-HSA-5632684
TCR signaling R-HSA-202403
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism R-HSA-1430728
Post-translational protein modification R-HSA-597592
Programmed Cell Death R-HSA-5357801
Stabilization of p53 R-HSA-69541
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Transport of small molecules R-HSA-382551
Cellular response to hypoxia R-HSA-1234174
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
G2/M Transition R-HSA-69275
Axon guidance R-HSA-422475
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic Anaphase R-HSA-68882
TCF dependent signaling in response to WNT R-HSA-201681
Defective CFTR causes cystic fibrosis R-HSA-5678895
Interleukin-1 family signaling R-HSA-446652
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Independent DNA Damage Response R-HSA-69610
Mitotic G1 phase and G1/S transition R-HSA-453279
M Phase R-HSA-68886
Signaling by Interleukins R-HSA-449147
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
UCH proteinases R-HSA-5689603
TCR signaling R-HSA-202403
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog 'off' state R-HSA-5610787
ABC transporter disorders R-HSA-5619084
Signaling by NOTCH R-HSA-157118
MAPK1/MAPK3 signaling R-HSA-5684996
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Stabilization of p53 R-HSA-69541
Switching of origins to a post-replicative state R-HSA-69052
Deubiquitination R-HSA-5688426
Transport of small molecules R-HSA-382551
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
FCERI mediated NF-kB activation R-HSA-2871837
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Disorders of transmembrane transporters R-HSA-5619115
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hh mutants are degraded by ERAD R-HSA-5362768
Programmed Cell Death R-HSA-5357801
Apoptosis R-HSA-109581
Gene expression (Transcription) R-HSA-74160
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hh mutants abrogate ligand secretion R-HSA-5387390
Adaptive Immune System R-HSA-1280218
S Phase R-HSA-69242
CLEC7A (Dectin-1) signaling R-HSA-5607764
Nervous system development R-HSA-9675108
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of GLI2 by the proteasome R-HSA-5610783
Synthesis of DNA R-HSA-69239
Hedgehog ligand biogenesis R-HSA-5358346
Hedgehog 'on' state R-HSA-5632684
Immune System R-HSA-168256
Infectious disease R-HSA-5663205
RNA Polymerase II Transcription R-HSA-73857
C-type lectin receptors (CLRs) R-HSA-5621481
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ub-specific processing proteases R-HSA-5689880
Metabolism of RNA R-HSA-8953854
Degradation of DVL R-HSA-4641258
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Separation of Sister Chromatids R-HSA-2467813
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cell Cycle, Mitotic R-HSA-69278
Cytokine Signaling in Immune system R-HSA-1280215
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
PTEN Regulation R-HSA-6807070
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Orc1 removal from chromatin R-HSA-68949
Cellular response to chemical stress R-HSA-9711123
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism R-HSA-1430728
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cyclin E associated events during G1/S transition R-HSA-69202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic G2-G2/M phases R-HSA-453274
Interleukin-1 signaling R-HSA-9020702
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of RAS by GAPs R-HSA-5658442
Activation of NF-kappaB in B cells R-HSA-1169091
KEAP1-NFE2L2 pathway R-HSA-9755511
Negative regulation of NOTCH4 signaling R-HSA-9604323
G1/S DNA Damage Checkpoints R-HSA-69615
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Innate Immune System R-HSA-168249
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Degradation of AXIN R-HSA-4641257
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Neddylation R-HSA-8951664
Cell Cycle Checkpoints R-HSA-69620
Regulation of Apoptosis R-HSA-169911
ABC-family proteins mediated transport R-HSA-382556
DNA Replication Pre-Initiation R-HSA-69002
PIP3 activates AKT signaling R-HSA-1257604
Regulation of mitotic cell cycle R-HSA-453276
Transcriptional regulation by RUNX1 R-HSA-8878171
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular responses to stress R-HSA-2262752
Assembly of the pre-replicative complex R-HSA-68867
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Generic Transcription Pathway R-HSA-212436
Regulation of PTEN stability and activity R-HSA-8948751
ER-Phagosome pathway R-HSA-1236974
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cell Cycle R-HSA-1640170
Metabolism of proteins R-HSA-392499
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G2/M Checkpoints R-HSA-69481
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stimuli R-HSA-8953897
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Asymmetric localization of PCP proteins R-HSA-4608870
Antigen processing-Cross presentation R-HSA-1236975
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Intracellular signaling by second messengers R-HSA-9006925
MAPK family signaling cascades R-HSA-5683057
Regulation of RUNX2 expression and activity R-HSA-8939902
PCP/CE pathway R-HSA-4086400
Downstream TCR signaling R-HSA-202424
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Developmental Biology R-HSA-1266738
Signaling by Hedgehog R-HSA-5358351
Signaling by ROBO receptors R-HSA-376176
Degradation of GLI1 by the proteasome R-HSA-5610780
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX2 R-HSA-8878166
Host Interactions of HIV factors R-HSA-162909
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
p53-Dependent G1 DNA Damage Response R-HSA-69563
DNA Replication R-HSA-69306
G1/S Transition R-HSA-69206
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of polyamines R-HSA-351202
Vpu mediated degradation of CD4 R-HSA-180534
HIV Infection R-HSA-162906
Regulation of RUNX3 expression and activity R-HSA-8941858
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by NOTCH4 R-HSA-9013694
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Post-translational protein modification R-HSA-597592
Signaling by ROBO receptors R-HSA-376176
M Phase R-HSA-68886
DNA Replication Pre-Initiation R-HSA-69002
Stabilization of p53 R-HSA-69541
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of AXIN R-HSA-4641257
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Dependent G1 DNA Damage Response R-HSA-69563
PIP3 activates AKT signaling R-HSA-1257604
Cellular responses to stimuli R-HSA-8953897
Vpu mediated degradation of CD4 R-HSA-180534
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism of polyamines R-HSA-351202
Hedgehog 'off' state R-HSA-5610787
Adaptive Immune System R-HSA-1280218
Separation of Sister Chromatids R-HSA-2467813
Regulation of PTEN stability and activity R-HSA-8948751
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
HIV Infection R-HSA-162906
Antigen processing-Cross presentation R-HSA-1236975
MAPK6/MAPK4 signaling R-HSA-5687128
Neddylation R-HSA-8951664
Nervous system development R-HSA-9675108
Orc1 removal from chromatin R-HSA-68949
Defective CFTR causes cystic fibrosis R-HSA-5678895
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cell Cycle Checkpoints R-HSA-69620
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle, Mitotic R-HSA-69278
Apoptosis R-HSA-109581
Nuclear events mediated by NFE2L2 R-HSA-9759194
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Mitotic Anaphase R-HSA-68882
Immune System R-HSA-168256
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of GLI2 by the proteasome R-HSA-5610783
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of RUNX3 expression and activity R-HSA-8941858
Disorders of transmembrane transporters R-HSA-5619115
Signaling by Hedgehog R-HSA-5358351
Hh mutants abrogate ligand secretion R-HSA-5387390
FCERI mediated NF-kB activation R-HSA-2871837
Interleukin-1 family signaling R-HSA-446652
Vif-mediated degradation of APOBEC3G R-HSA-180585
Synthesis of DNA R-HSA-69239
ABC transporter disorders R-HSA-5619084
Programmed Cell Death R-HSA-5357801
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
PCP/CE pathway R-HSA-4086400
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
G2/M Transition R-HSA-69275
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Mitotic Metaphase and Anaphase R-HSA-2555396
TCR signaling R-HSA-202403
Metabolism of proteins R-HSA-392499
Signal Transduction R-HSA-162582
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Disease R-HSA-1643685
Signaling by WNT R-HSA-195721
G1/S DNA Damage Checkpoints R-HSA-69615
Hh mutants are degraded by ERAD R-HSA-5362768
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Innate Immune System R-HSA-168249
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Interleukin-1 signaling R-HSA-9020702
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular response to chemical stress R-HSA-9711123
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
ER-Phagosome pathway R-HSA-1236974
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of Apoptosis R-HSA-169911
Metabolism of RNA R-HSA-8953854
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Post-translational protein modification R-HSA-597592
Intracellular signaling by second messengers R-HSA-9006925
RNA Polymerase II Transcription R-HSA-73857
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transcriptional regulation by RUNX1 R-HSA-8878171
Hedgehog 'on' state R-HSA-5632684
DNA Replication R-HSA-69306
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of DVL R-HSA-4641258
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
S Phase R-HSA-69242
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
RAF/MAP kinase cascade R-HSA-5673001
Switching of origins to a post-replicative state R-HSA-69052
Cyclin E associated events during G1/S transition R-HSA-69202
UCH proteinases R-HSA-5689603
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
Negative regulation of NOTCH4 signaling R-HSA-9604323
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Interleukins R-HSA-449147
Infectious disease R-HSA-5663205
PTEN Regulation R-HSA-6807070
Class I MHC mediated antigen processing & presentation R-HSA-983169
Developmental Biology R-HSA-1266738
Cell Cycle R-HSA-1640170
Regulation of expression of SLITs and ROBOs R-HSA-9010553
G2/M Checkpoints R-HSA-69481
Generic Transcription Pathway R-HSA-212436
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
p53-Independent DNA Damage Response R-HSA-69610
Downstream TCR signaling R-HSA-202424
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by NOTCH R-HSA-157118
Assembly of the pre-replicative complex R-HSA-68867
Gene expression (Transcription) R-HSA-74160
ABC-family proteins mediated transport R-HSA-382556
Host Interactions of HIV factors R-HSA-162909
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional regulation by RUNX3 R-HSA-8878159
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Beta-catenin independent WNT signaling R-HSA-3858494
Deubiquitination R-HSA-5688426
Metabolism R-HSA-1430728
G1/S Transition R-HSA-69206
Metabolism of amino acids and derivatives R-HSA-71291
MAPK1/MAPK3 signaling R-HSA-5684996
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
MAPK family signaling cascades R-HSA-5683057
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cellular response to hypoxia R-HSA-1234174
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular responses to stress R-HSA-2262752
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ub-specific processing proteases R-HSA-5689880
Transport of small molecules R-HSA-382551
Regulation of mitotic cell cycle R-HSA-453276
Regulation of RAS by GAPs R-HSA-5658442
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication Pre-Initiation R-HSA-69002
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Assembly of the pre-replicative complex R-HSA-68867
Synthesis of DNA R-HSA-69239
Programmed Cell Death R-HSA-5357801
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of RUNX3 expression and activity R-HSA-8941858
Interleukin-1 family signaling R-HSA-446652
Transport of small molecules R-HSA-382551
Hedgehog ligand biogenesis R-HSA-5358346
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing-Cross presentation R-HSA-1236975
Degradation of GLI1 by the proteasome R-HSA-5610780
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Transition R-HSA-69275
Host Interactions of HIV factors R-HSA-162909
Separation of Sister Chromatids R-HSA-2467813
Degradation of DVL R-HSA-4641258
HIV Infection R-HSA-162906
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Developmental Biology R-HSA-1266738
Degradation of beta-catenin by the destruction complex R-HSA-195253
ABC-family proteins mediated transport R-HSA-382556
Cellular responses to stimuli R-HSA-8953897
Signaling by Hedgehog R-HSA-5358351
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Post-translational protein modification R-HSA-597592
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of mitotic cell cycle R-HSA-453276
Orc1 removal from chromatin R-HSA-68949
M Phase R-HSA-68886
ER-Phagosome pathway R-HSA-1236974
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cyclin E associated events during G1/S transition R-HSA-69202
Hh mutants abrogate ligand secretion R-HSA-5387390
Signaling by ROBO receptors R-HSA-376176
MAPK family signaling cascades R-HSA-5683057
G1/S Transition R-HSA-69206
Activation of NF-kappaB in B cells R-HSA-1169091
G1/S DNA Damage Checkpoints R-HSA-69615
CLEC7A (Dectin-1) signaling R-HSA-5607764
Asymmetric localization of PCP proteins R-HSA-4608870
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Class I MHC mediated antigen processing & presentation R-HSA-983169
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of RAS by GAPs R-HSA-5658442
Generic Transcription Pathway R-HSA-212436
Signaling by WNT R-HSA-195721
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Intracellular signaling by second messengers R-HSA-9006925
Deubiquitination R-HSA-5688426
Degradation of AXIN R-HSA-4641257
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of proteins R-HSA-392499
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Vpu mediated degradation of CD4 R-HSA-180534
KEAP1-NFE2L2 pathway R-HSA-9755511
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PCP/CE pathway R-HSA-4086400
Mitotic Anaphase R-HSA-68882
Apoptosis R-HSA-109581
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Disease R-HSA-1643685
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX2 R-HSA-8878166
Cell Cycle R-HSA-1640170
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Stabilization of p53 R-HSA-69541
PTEN Regulation R-HSA-6807070
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
FCERI mediated NF-kB activation R-HSA-2871837
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cellular response to chemical stress R-HSA-9711123
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of Apoptosis R-HSA-169911
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
G2/M Checkpoints R-HSA-69481
Mitotic G1 phase and G1/S transition R-HSA-453279
Interleukin-1 signaling R-HSA-9020702
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PIP3 activates AKT signaling R-HSA-1257604
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic Metaphase and Anaphase R-HSA-2555396
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Adaptive Immune System R-HSA-1280218
C-type lectin receptors (CLRs) R-HSA-5621481
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
DNA Replication R-HSA-69306
Cellular response to hypoxia R-HSA-1234174
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle, Mitotic R-HSA-69278
Gene expression (Transcription) R-HSA-74160
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by NOTCH R-HSA-157118
UCH proteinases R-HSA-5689603
Beta-catenin independent WNT signaling R-HSA-3858494
Infectious disease R-HSA-5663205
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cell Cycle Checkpoints R-HSA-69620
p53-Independent DNA Damage Response R-HSA-69610
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Hedgehog 'off' state R-HSA-5610787
Downstream TCR signaling R-HSA-202424
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism R-HSA-1430728
Ub-specific processing proteases R-HSA-5689880
ABC transporter disorders R-HSA-5619084
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Immune System R-HSA-168256
RNA Polymerase II Transcription R-HSA-73857
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX3 R-HSA-8878159
Neddylation R-HSA-8951664
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK1/MAPK3 signaling R-HSA-5684996
Hedgehog 'on' state R-HSA-5632684
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of PTEN stability and activity R-HSA-8948751
Transcriptional regulation by RUNX1 R-HSA-8878171
Switching of origins to a post-replicative state R-HSA-69052
Vif-mediated degradation of APOBEC3G R-HSA-180585
Metabolism of polyamines R-HSA-351202
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signal Transduction R-HSA-162582
Signaling by NOTCH4 R-HSA-9013694
TCR signaling R-HSA-202403
Cellular responses to stress R-HSA-2262752
Metabolism of RNA R-HSA-8953854
Nuclear events mediated by NFE2L2 R-HSA-9759194
Axon guidance R-HSA-422475
Metabolism of amino acids and derivatives R-HSA-71291
Innate Immune System R-HSA-168249
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of proteins R-HSA-392499
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
S Phase R-HSA-69242
Gene expression (Transcription) R-HSA-74160
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog 'on' state R-HSA-5632684
Infectious disease R-HSA-5663205
DNA Replication Pre-Initiation R-HSA-69002
RNA Polymerase II Transcription R-HSA-73857
Orc1 removal from chromatin R-HSA-68949
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cyclin E associated events during G1/S transition R-HSA-69202
Axon guidance R-HSA-422475
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Dependent G1 DNA Damage Response R-HSA-69563
Transport of small molecules R-HSA-382551
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular response to hypoxia R-HSA-1234174
ER-Phagosome pathway R-HSA-1236974
Transcriptional regulation by RUNX3 R-HSA-8878159
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Vpu mediated degradation of CD4 R-HSA-180534
Post-translational protein modification R-HSA-597592
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
Metabolism of RNA R-HSA-8953854
G2/M Checkpoints R-HSA-69481
Metabolism of polyamines R-HSA-351202
Antigen processing-Cross presentation R-HSA-1236975
Cytokine Signaling in Immune system R-HSA-1280215
Cell Cycle, Mitotic R-HSA-69278
Signaling by Hedgehog R-HSA-5358351
Mitotic G1 phase and G1/S transition R-HSA-453279
Neddylation R-HSA-8951664
TCR signaling R-HSA-202403
Class I MHC mediated antigen processing & presentation R-HSA-983169
Interleukin-1 family signaling R-HSA-446652
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of DVL R-HSA-4641258
Stabilization of p53 R-HSA-69541
Disease R-HSA-1643685
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Switching of origins to a post-replicative state R-HSA-69052
Defective CFTR causes cystic fibrosis R-HSA-5678895
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hh mutants are degraded by ERAD R-HSA-5362768
Immune System R-HSA-168256
TCF dependent signaling in response to WNT R-HSA-201681
Hh mutants abrogate ligand secretion R-HSA-5387390
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
PTEN Regulation R-HSA-6807070
Cellular responses to stress R-HSA-2262752
Signaling by NOTCH4 R-HSA-9013694
Activation of NF-kappaB in B cells R-HSA-1169091
Assembly of the pre-replicative complex R-HSA-68867
Apoptosis R-HSA-109581
Signaling by Interleukins R-HSA-449147
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of mitotic cell cycle R-HSA-453276
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular responses to stimuli R-HSA-8953897
G1/S DNA Damage Checkpoints R-HSA-69615
KEAP1-NFE2L2 pathway R-HSA-9755511
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Independent DNA Damage Response R-HSA-69610
Regulation of Apoptosis R-HSA-169911
Mitotic Metaphase and Anaphase R-HSA-2555396
Nuclear events mediated by NFE2L2 R-HSA-9759194
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ABC transporter disorders R-HSA-5619084
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Intracellular signaling by second messengers R-HSA-9006925
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by NOTCH R-HSA-157118
ABC-family proteins mediated transport R-HSA-382556
Adaptive Immune System R-HSA-1280218
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G1/S Transition R-HSA-69206
Host Interactions of HIV factors R-HSA-162909
MAPK1/MAPK3 signaling R-HSA-5684996
Transcriptional regulation by RUNX1 R-HSA-8878171
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of beta-catenin by the destruction complex R-HSA-195253
PCP/CE pathway R-HSA-4086400
Downstream TCR signaling R-HSA-202424
Separation of Sister Chromatids R-HSA-2467813
Programmed Cell Death R-HSA-5357801
PIP3 activates AKT signaling R-HSA-1257604
M Phase R-HSA-68886
Synthesis of DNA R-HSA-69239
Regulation of RAS by GAPs R-HSA-5658442
Cellular response to chemical stress R-HSA-9711123
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK family signaling cascades R-HSA-5683057
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of GLI1 by the proteasome R-HSA-5610780
Vif-mediated degradation of APOBEC3G R-HSA-180585
Generic Transcription Pathway R-HSA-212436
G2/M Transition R-HSA-69275
RAF/MAP kinase cascade R-HSA-5673001
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Mitotic G2-G2/M phases R-HSA-453274
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of AXIN R-HSA-4641257
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by WNT R-HSA-195721
Hedgehog 'off' state R-HSA-5610787
Ub-specific processing proteases R-HSA-5689880
Nervous system development R-HSA-9675108
Hedgehog ligand biogenesis R-HSA-5358346
Beta-catenin independent WNT signaling R-HSA-3858494
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
UCH proteinases R-HSA-5689603
DNA Replication R-HSA-69306
Disorders of transmembrane transporters R-HSA-5619115
Regulation of RUNX2 expression and activity R-HSA-8939902
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism R-HSA-1430728
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
HIV Infection R-HSA-162906
Regulation of PTEN stability and activity R-HSA-8948751
Deubiquitination R-HSA-5688426
Cell Cycle R-HSA-1640170
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Mitotic Anaphase R-HSA-68882
Interleukin-1 signaling R-HSA-9020702
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by ROBO receptors R-HSA-376176
Degradation of GLI2 by the proteasome R-HSA-5610783
Cell Cycle Checkpoints R-HSA-69620
Vpu mediated degradation of CD4 R-HSA-180534
Activation of NF-kappaB in B cells R-HSA-1169091
ABC transporter disorders R-HSA-5619084
TCR signaling R-HSA-202403
Separation of Sister Chromatids R-HSA-2467813
Defective CFTR causes cystic fibrosis R-HSA-5678895
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by the B Cell Receptor (BCR) R-HSA-983705
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1 DNA Damage Response R-HSA-69563
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Axon guidance R-HSA-422475
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
G1/S Transition R-HSA-69206
Innate Immune System R-HSA-168249
Interleukin-1 family signaling R-HSA-446652
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Apoptosis R-HSA-109581
Cyclin E associated events during G1/S transition R-HSA-69202
DNA Replication Pre-Initiation R-HSA-69002
PTEN Regulation R-HSA-6807070
Interleukin-1 signaling R-HSA-9020702
Disorders of transmembrane transporters R-HSA-5619115
M Phase R-HSA-68886
Degradation of GLI1 by the proteasome R-HSA-5610780
DNA Replication R-HSA-69306
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Immune System R-HSA-168256
Hedgehog ligand biogenesis R-HSA-5358346
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RAS by GAPs R-HSA-5658442
Regulation of mitotic cell cycle R-HSA-453276
Metabolism R-HSA-1430728
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by WNT R-HSA-195721
HIV Infection R-HSA-162906
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX2 expression and activity R-HSA-8939902
G2/M Transition R-HSA-69275
Regulation of Apoptosis R-HSA-169911
Signaling by NOTCH R-HSA-157118
Cellular responses to stress R-HSA-2262752
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Negative regulation of NOTCH4 signaling R-HSA-9604323
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
ABC-family proteins mediated transport R-HSA-382556
Signaling by ROBO receptors R-HSA-376176
Asymmetric localization of PCP proteins R-HSA-4608870
Antigen processing-Cross presentation R-HSA-1236975
FCERI mediated NF-kB activation R-HSA-2871837
Hedgehog 'off' state R-HSA-5610787
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
ER-Phagosome pathway R-HSA-1236974
Cell Cycle, Mitotic R-HSA-69278
Degradation of DVL R-HSA-4641258
Mitotic G2-G2/M phases R-HSA-453274
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cellular responses to stimuli R-HSA-8953897
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Intracellular signaling by second messengers R-HSA-9006925
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Host Interactions of HIV factors R-HSA-162909
Orc1 removal from chromatin R-HSA-68949
Deubiquitination R-HSA-5688426
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX2 R-HSA-8878166
Infectious disease R-HSA-5663205
Synthesis of DNA R-HSA-69239
Degradation of GLI2 by the proteasome R-HSA-5610783
Transcriptional regulation by RUNX3 R-HSA-8878159
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism of proteins R-HSA-392499
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Neddylation R-HSA-8951664
Gene expression (Transcription) R-HSA-74160
CLEC7A (Dectin-1) signaling R-HSA-5607764
Developmental Biology R-HSA-1266738
Signaling by Interleukins R-HSA-449147
C-type lectin receptors (CLRs) R-HSA-5621481
G1/S DNA Damage Checkpoints R-HSA-69615
Cellular response to hypoxia R-HSA-1234174
Signaling by Hedgehog R-HSA-5358351
Post-translational protein modification R-HSA-597592
Stabilization of p53 R-HSA-69541
Signaling by NOTCH4 R-HSA-9013694
G2/M Checkpoints R-HSA-69481
TCF dependent signaling in response to WNT R-HSA-201681
Hedgehog 'on' state R-HSA-5632684
MAPK1/MAPK3 signaling R-HSA-5684996
Transport of small molecules R-HSA-382551
Nuclear events mediated by NFE2L2 R-HSA-9759194
Programmed Cell Death R-HSA-5357801
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
Assembly of the pre-replicative complex R-HSA-68867
S Phase R-HSA-69242
Degradation of AXIN R-HSA-4641257
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Mitotic Anaphase R-HSA-68882
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Nervous system development R-HSA-9675108
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of RNA R-HSA-8953854
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Class I MHC mediated antigen processing & presentation R-HSA-983169
Downstream TCR signaling R-HSA-202424
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Transcriptional regulation by RUNX1 R-HSA-8878171
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Independent DNA Damage Response R-HSA-69610
Adaptive Immune System R-HSA-1280218
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Generic Transcription Pathway R-HSA-212436
Metabolism of amino acids and derivatives R-HSA-71291
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
MAPK6/MAPK4 signaling R-HSA-5687128
Ub-specific processing proteases R-HSA-5689880
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Beta-catenin independent WNT signaling R-HSA-3858494
PCP/CE pathway R-HSA-4086400
Mitotic G1 phase and G1/S transition R-HSA-453279
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle Checkpoints R-HSA-69620
Switching of origins to a post-replicative state R-HSA-69052
Disease R-HSA-1643685
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PIP3 activates AKT signaling R-HSA-1257604
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of polyamines R-HSA-351202
PCP/CE pathway R-HSA-4086400
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Defective CFTR causes cystic fibrosis R-HSA-5678895
Nervous system development R-HSA-9675108
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cellular response to hypoxia R-HSA-1234174
Metabolism R-HSA-1430728
MAPK family signaling cascades R-HSA-5683057
Signaling by NOTCH R-HSA-157118
Degradation of DVL R-HSA-4641258
Axon guidance R-HSA-422475
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RAS by GAPs R-HSA-5658442
Adaptive Immune System R-HSA-1280218
NIK-->noncanonical NF-kB signaling R-HSA-5676590
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Antigen processing-Cross presentation R-HSA-1236975
Separation of Sister Chromatids R-HSA-2467813
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX1 R-HSA-8878171
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
M Phase R-HSA-68886
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Synthesis of DNA R-HSA-69239
Degradation of AXIN R-HSA-4641257
ABC-family proteins mediated transport R-HSA-382556
G1/S DNA Damage Checkpoints R-HSA-69615
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 family signaling R-HSA-446652
Downstream TCR signaling R-HSA-202424
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular responses to stimuli R-HSA-8953897
Hh mutants are degraded by ERAD R-HSA-5362768
RAF/MAP kinase cascade R-HSA-5673001
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle R-HSA-1640170
C-type lectin receptors (CLRs) R-HSA-5621481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Interleukin-1 signaling R-HSA-9020702
Degradation of GLI2 by the proteasome R-HSA-5610783
Activation of NF-kappaB in B cells R-HSA-1169091
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Metabolism of proteins R-HSA-392499
Vpu mediated degradation of CD4 R-HSA-180534
Innate Immune System R-HSA-168249
Ub-specific processing proteases R-HSA-5689880
Metabolism of amino acids and derivatives R-HSA-71291
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cell Cycle, Mitotic R-HSA-69278
Signaling by WNT R-HSA-195721
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
PTEN Regulation R-HSA-6807070
DNA Replication R-HSA-69306
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Assembly of the pre-replicative complex R-HSA-68867
Hedgehog 'off' state R-HSA-5610787
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
Deubiquitination R-HSA-5688426
Cell Cycle Checkpoints R-HSA-69620
Mitotic Metaphase and Anaphase R-HSA-2555396
Cellular responses to stress R-HSA-2262752
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G2/M Checkpoints R-HSA-69481
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of Apoptosis R-HSA-169911
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of polyamines R-HSA-351202
ER-Phagosome pathway R-HSA-1236974
Beta-catenin independent WNT signaling R-HSA-3858494
Neddylation R-HSA-8951664
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
KEAP1-NFE2L2 pathway R-HSA-9755511
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cellular response to chemical stress R-HSA-9711123
Regulation of RUNX2 expression and activity R-HSA-8939902
FCERI mediated NF-kB activation R-HSA-2871837
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by ROBO receptors R-HSA-376176
Class I MHC mediated antigen processing & presentation R-HSA-983169
RNA Polymerase II Transcription R-HSA-73857
Stabilization of p53 R-HSA-69541
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Disease R-HSA-1643685
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK6/MAPK4 signaling R-HSA-5687128
Mitotic G1 phase and G1/S transition R-HSA-453279
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by NOTCH4 R-HSA-9013694
Cyclin E associated events during G1/S transition R-HSA-69202
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of RNA R-HSA-8953854
UCH proteinases R-HSA-5689603
Orc1 removal from chromatin R-HSA-68949
Infectious disease R-HSA-5663205
G1/S Transition R-HSA-69206
Signaling by Hedgehog R-HSA-5358351
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Host Interactions of HIV factors R-HSA-162909
Degradation of beta-catenin by the destruction complex R-HSA-195253
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
S Phase R-HSA-69242
Cytokine Signaling in Immune system R-HSA-1280215
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Post-translational protein modification R-HSA-597592
G2/M Transition R-HSA-69275
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
TCR signaling R-HSA-202403
Transport of small molecules R-HSA-382551
Gene expression (Transcription) R-HSA-74160
Mitotic G2-G2/M phases R-HSA-453274
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by Interleukins R-HSA-449147
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of GLI1 by the proteasome R-HSA-5610780
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic Anaphase R-HSA-68882
Hedgehog 'on' state R-HSA-5632684
HIV Infection R-HSA-162906
Switching of origins to a post-replicative state R-HSA-69052
Vif-mediated degradation of APOBEC3G R-HSA-180585
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of mitotic cell cycle R-HSA-453276
Immune System R-HSA-168256
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Hedgehog ligand biogenesis R-HSA-5358346
Intracellular signaling by second messengers R-HSA-9006925
Developmental Biology R-HSA-1266738
DNA Replication Pre-Initiation R-HSA-69002
Apoptosis R-HSA-109581
p53-Independent DNA Damage Response R-HSA-69610
C-type lectin receptors (CLRs) R-HSA-5621481
Cyclin E associated events during G1/S transition R-HSA-69202
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular response to hypoxia R-HSA-1234174
Cell Cycle Checkpoints R-HSA-69620
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Interleukin-1 signaling R-HSA-9020702
MAPK family signaling cascades R-HSA-5683057
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX3 R-HSA-8878159
Ub-specific processing proteases R-HSA-5689880
Hedgehog 'on' state R-HSA-5632684
Innate Immune System R-HSA-168249
Hedgehog 'off' state R-HSA-5610787
Regulation of RUNX2 expression and activity R-HSA-8939902
Intracellular signaling by second messengers R-HSA-9006925
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Vpu mediated degradation of CD4 R-HSA-180534
Signal Transduction R-HSA-162582
Beta-catenin independent WNT signaling R-HSA-3858494
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of GLI2 by the proteasome R-HSA-5610783
Deubiquitination R-HSA-5688426
Signaling by ROBO receptors R-HSA-376176
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of proteins R-HSA-392499
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Developmental Biology R-HSA-1266738
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
UCH proteinases R-HSA-5689603
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Downstream TCR signaling R-HSA-202424
Signaling by Hedgehog R-HSA-5358351
Host Interactions of HIV factors R-HSA-162909
Signaling by NOTCH4 R-HSA-9013694
Adaptive Immune System R-HSA-1280218
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by NOTCH R-HSA-157118
PCP/CE pathway R-HSA-4086400
M Phase R-HSA-68886
Asymmetric localization of PCP proteins R-HSA-4608870
Degradation of DVL R-HSA-4641258
Cellular response to chemical stress R-HSA-9711123
G1/S Transition R-HSA-69206
Post-translational protein modification R-HSA-597592
Infectious disease R-HSA-5663205
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Defective CFTR causes cystic fibrosis R-HSA-5678895
Axon guidance R-HSA-422475
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
p53-Independent DNA Damage Response R-HSA-69610
Mitotic G2-G2/M phases R-HSA-453274
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of Apoptosis R-HSA-169911
Vif-mediated degradation of APOBEC3G R-HSA-180585
Disease R-HSA-1643685
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
RNA Polymerase II Transcription R-HSA-73857
Synthesis of DNA R-HSA-69239
ER-Phagosome pathway R-HSA-1236974
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Mitotic G1 phase and G1/S transition R-HSA-453279
RAF/MAP kinase cascade R-HSA-5673001
Degradation of beta-catenin by the destruction complex R-HSA-195253
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
G2/M Checkpoints R-HSA-69481
ABC transporter disorders R-HSA-5619084
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transport of small molecules R-HSA-382551
HIV Infection R-HSA-162906
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Metabolism R-HSA-1430728
Regulation of mitotic cell cycle R-HSA-453276
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of RUNX3 expression and activity R-HSA-8941858
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by WNT R-HSA-195721
Neddylation R-HSA-8951664
G1/S DNA Damage Checkpoints R-HSA-69615
Cell Cycle, Mitotic R-HSA-69278
Metabolism of polyamines R-HSA-351202
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
PIP3 activates AKT signaling R-HSA-1257604
Activation of NF-kappaB in B cells R-HSA-1169091
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
DNA Replication Pre-Initiation R-HSA-69002
MAPK1/MAPK3 signaling R-HSA-5684996
Transcriptional regulation by RUNX1 R-HSA-8878171
Interleukin-1 family signaling R-HSA-446652
Separation of Sister Chromatids R-HSA-2467813
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Antigen processing-Cross presentation R-HSA-1236975
Gene expression (Transcription) R-HSA-74160
Hh mutants are degraded by ERAD R-HSA-5362768
Stabilization of p53 R-HSA-69541
Cellular responses to stimuli R-HSA-8953897
Regulation of PTEN stability and activity R-HSA-8948751
Generic Transcription Pathway R-HSA-212436
Orc1 removal from chromatin R-HSA-68949
TCR signaling R-HSA-202403
Degradation of AXIN R-HSA-4641257
Mitotic Anaphase R-HSA-68882
DNA Replication R-HSA-69306
Programmed Cell Death R-HSA-5357801
Metabolism of amino acids and derivatives R-HSA-71291
Cellular responses to stress R-HSA-2262752
Cell Cycle R-HSA-1640170
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TCF dependent signaling in response to WNT R-HSA-201681
Assembly of the pre-replicative complex R-HSA-68867
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of RAS by GAPs R-HSA-5658442
PTEN Regulation R-HSA-6807070
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Switching of origins to a post-replicative state R-HSA-69052
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
S Phase R-HSA-69242
CLEC7A (Dectin-1) signaling R-HSA-5607764
ABC-family proteins mediated transport R-HSA-382556
G2/M Transition R-HSA-69275
Cytokine Signaling in Immune system R-HSA-1280215
Apoptosis R-HSA-109581
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Nervous system development R-HSA-9675108
Disorders of transmembrane transporters R-HSA-5619115
Regulation of expression of SLITs and ROBOs R-HSA-9010553
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
FCERI mediated NF-kB activation R-HSA-2871837
Metabolism of RNA R-HSA-8953854
Signaling by Interleukins R-HSA-449147
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Programmed Cell Death R-HSA-5357801
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by the B Cell Receptor (BCR) R-HSA-983705
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Post-translational protein modification R-HSA-597592
Cellular responses to stimuli R-HSA-8953897
Separation of Sister Chromatids R-HSA-2467813
M Phase R-HSA-68886
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
DNA Replication Pre-Initiation R-HSA-69002
PTEN Regulation R-HSA-6807070
Downstream TCR signaling R-HSA-202424
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hh mutants are degraded by ERAD R-HSA-5362768
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Interleukin-1 family signaling R-HSA-446652
Cell Cycle R-HSA-1640170
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of beta-catenin by the destruction complex R-HSA-195253
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by ROBO receptors R-HSA-376176
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cyclin E associated events during G1/S transition R-HSA-69202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular response to chemical stress R-HSA-9711123
G1/S Transition R-HSA-69206
Disease R-HSA-1643685
Neddylation R-HSA-8951664
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Stabilization of p53 R-HSA-69541
UCH proteinases R-HSA-5689603
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Developmental Biology R-HSA-1266738
FCERI mediated NF-kB activation R-HSA-2871837
Vpu mediated degradation of CD4 R-HSA-180534
S Phase R-HSA-69242
Transport of small molecules R-HSA-382551
NIK-->noncanonical NF-kB signaling R-HSA-5676590
p53-Independent DNA Damage Response R-HSA-69610
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism of proteins R-HSA-392499
G1/S DNA Damage Checkpoints R-HSA-69615
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Nervous system development R-HSA-9675108
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Regulation of mitotic cell cycle R-HSA-453276
ABC-family proteins mediated transport R-HSA-382556
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Innate Immune System R-HSA-168249
Transcriptional regulation by RUNX1 R-HSA-8878171
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Nuclear events mediated by NFE2L2 R-HSA-9759194
G2/M Checkpoints R-HSA-69481
PCP/CE pathway R-HSA-4086400
Signaling by Interleukins R-HSA-449147
Metabolism of RNA R-HSA-8953854
RAF/MAP kinase cascade R-HSA-5673001
Signaling by NOTCH4 R-HSA-9013694
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle Checkpoints R-HSA-69620
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hh mutants abrogate ligand secretion R-HSA-5387390
Immune System R-HSA-168256
PIP3 activates AKT signaling R-HSA-1257604
Degradation of DVL R-HSA-4641258
TCR signaling R-HSA-202403
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Metabolism of polyamines R-HSA-351202
Activation of NF-kappaB in B cells R-HSA-1169091
G2/M Transition R-HSA-69275
Ub-specific processing proteases R-HSA-5689880
Switching of origins to a post-replicative state R-HSA-69052
Regulation of RUNX3 expression and activity R-HSA-8941858
Synthesis of DNA R-HSA-69239
Host Interactions of HIV factors R-HSA-162909
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by Hedgehog R-HSA-5358351
Signal Transduction R-HSA-162582
Mitotic Anaphase R-HSA-68882
Beta-catenin independent WNT signaling R-HSA-3858494
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Metabolism R-HSA-1430728
ABC transporter disorders R-HSA-5619084
Disorders of transmembrane transporters R-HSA-5619115
Mitotic G2-G2/M phases R-HSA-453274
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RAS by GAPs R-HSA-5658442
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hedgehog 'off' state R-HSA-5610787
Axon guidance R-HSA-422475
Signaling by NOTCH R-HSA-157118
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of AXIN R-HSA-4641257
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Generic Transcription Pathway R-HSA-212436
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX3 R-HSA-8878159
Adaptive Immune System R-HSA-1280218
Cytokine Signaling in Immune system R-HSA-1280215
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hedgehog 'on' state R-HSA-5632684
Mitotic Metaphase and Anaphase R-HSA-2555396
ER-Phagosome pathway R-HSA-1236974
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of GLI2 by the proteasome R-HSA-5610783
TCF dependent signaling in response to WNT R-HSA-201681
RNA Polymerase II Transcription R-HSA-73857
HIV Infection R-HSA-162906
MAPK1/MAPK3 signaling R-HSA-5684996
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of Apoptosis R-HSA-169911
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Deubiquitination R-HSA-5688426
Assembly of the pre-replicative complex R-HSA-68867
Intracellular signaling by second messengers R-HSA-9006925
DNA Replication R-HSA-69306
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by WNT R-HSA-195721
Interleukin-1 signaling R-HSA-9020702
Infectious disease R-HSA-5663205
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Gene expression (Transcription) R-HSA-74160
Regulation of PTEN stability and activity R-HSA-8948751
Apoptosis R-HSA-109581
Metabolism of amino acids and derivatives R-HSA-71291
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Dependent G1 DNA Damage Response R-HSA-69563
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular responses to stress R-HSA-2262752
MAPK family signaling cascades R-HSA-5683057
C-type lectin receptors (CLRs) R-HSA-5621481
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cellular response to hypoxia R-HSA-1234174

Expression Atlas ENSG00000205220
NCBI gene (formerly Entrezgene) 5699
GeneCards 9538
HGNC Symbol HGNC:9538
MIM gene 176847
MIM morbid 619175
UniProtKB Gene Name P40306
WikiGene 5699
Gene: PSMA5
Ensembl ID : ENSG00000143106
Description: proteasome 20S subunit alpha 5
Gene Synonyms: ZETA
6 APIs:
211 Possible Orthologues:

M Phase R-HSA-68886
Vpu mediated degradation of CD4 R-HSA-180534
Hedgehog 'off' state R-HSA-5610787
Immune System R-HSA-168256
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Checkpoints R-HSA-69481
Intracellular signaling by second messengers R-HSA-9006925
MAPK1/MAPK3 signaling R-HSA-5684996
ER-Phagosome pathway R-HSA-1236974
Ub-specific processing proteases R-HSA-5689880
Signaling by Interleukins R-HSA-449147
Regulation of RAS by GAPs R-HSA-5658442
Interleukin-1 family signaling R-HSA-446652
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Metabolism of proteins R-HSA-392499
Regulation of RUNX3 expression and activity R-HSA-8941858
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Programmed Cell Death R-HSA-5357801
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of DVL R-HSA-4641258
Neddylation R-HSA-8951664
Transcriptional regulation by RUNX2 R-HSA-8878166
p53-Dependent G1 DNA Damage Response R-HSA-69563
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
UCH proteinases R-HSA-5689603
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Defective CFTR causes cystic fibrosis R-HSA-5678895
p53-Independent DNA Damage Response R-HSA-69610
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Synthesis of DNA R-HSA-69239
C-type lectin receptors (CLRs) R-HSA-5621481
PIP3 activates AKT signaling R-HSA-1257604
Cellular responses to stimuli R-HSA-8953897
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of GLI2 by the proteasome R-HSA-5610783
Adaptive Immune System R-HSA-1280218
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Deubiquitination R-HSA-5688426
Transcriptional regulation by RUNX1 R-HSA-8878171
Switching of origins to a post-replicative state R-HSA-69052
Regulation of Apoptosis R-HSA-169911
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by Hedgehog R-HSA-5358351
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear events mediated by NFE2L2 R-HSA-9759194
DNA Replication Pre-Initiation R-HSA-69002
MAPK6/MAPK4 signaling R-HSA-5687128
ABC transporter disorders R-HSA-5619084
Mitotic G1 phase and G1/S transition R-HSA-453279
Asymmetric localization of PCP proteins R-HSA-4608870
Infectious disease R-HSA-5663205
Metabolism R-HSA-1430728
Mitotic Anaphase R-HSA-68882
Cell Cycle, Mitotic R-HSA-69278
Host Interactions of HIV factors R-HSA-162909
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX3 R-HSA-8878159
Hh mutants are degraded by ERAD R-HSA-5362768
S Phase R-HSA-69242
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of RUNX2 expression and activity R-HSA-8939902
Downstream TCR signaling R-HSA-202424
Disorders of transmembrane transporters R-HSA-5619115
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of GLI1 by the proteasome R-HSA-5610780
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cytokine Signaling in Immune system R-HSA-1280215
Hedgehog 'on' state R-HSA-5632684
G1/S Transition R-HSA-69206
Gene expression (Transcription) R-HSA-74160
Metabolism of polyamines R-HSA-351202
Generic Transcription Pathway R-HSA-212436
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism of amino acids and derivatives R-HSA-71291
Disease R-HSA-1643685
G2/M Transition R-HSA-69275
RNA Polymerase II Transcription R-HSA-73857
Cellular response to hypoxia R-HSA-1234174
MAPK family signaling cascades R-HSA-5683057
Axon guidance R-HSA-422475
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by NOTCH4 R-HSA-9013694
Cellular response to chemical stress R-HSA-9711123
HIV Infection R-HSA-162906
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Antigen processing-Cross presentation R-HSA-1236975
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PTEN Regulation R-HSA-6807070
Cell Cycle R-HSA-1640170
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of mitotic cell cycle R-HSA-453276
Orc1 removal from chromatin R-HSA-68949
Interleukin-1 signaling R-HSA-9020702
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Innate Immune System R-HSA-168249
Separation of Sister Chromatids R-HSA-2467813
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by ROBO receptors R-HSA-376176
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hedgehog ligand biogenesis R-HSA-5358346
Cellular responses to stress R-HSA-2262752
Signaling by NOTCH R-HSA-157118
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by WNT R-HSA-195721
DNA Replication R-HSA-69306
Negative regulation of NOTCH4 signaling R-HSA-9604323
PCP/CE pathway R-HSA-4086400
ABC-family proteins mediated transport R-HSA-382556
Post-translational protein modification R-HSA-597592
Mitotic G2-G2/M phases R-HSA-453274
Stabilization of p53 R-HSA-69541
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
TCR signaling R-HSA-202403
Apoptosis R-HSA-109581
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transport of small molecules R-HSA-382551
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Developmental Biology R-HSA-1266738
M Phase R-HSA-68886
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of RNA R-HSA-8953854
Neutrophil degranulation R-HSA-6798695
RAF/MAP kinase cascade R-HSA-5673001
Degradation of AXIN R-HSA-4641257
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cell Cycle Checkpoints R-HSA-69620
Nervous system development R-HSA-9675108
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of PTEN stability and activity R-HSA-8948751
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Assembly of the pre-replicative complex R-HSA-68867
Mitotic Metaphase and Anaphase R-HSA-2555396
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signal Transduction R-HSA-162582
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Ub-specific processing proteases R-HSA-5689880
Signaling by NOTCH4 R-HSA-9013694
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stimuli R-HSA-8953897
Deubiquitination R-HSA-5688426
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
Transport of small molecules R-HSA-382551
Cellular response to chemical stress R-HSA-9711123
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disorders of transmembrane transporters R-HSA-5619115
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Post-translational protein modification R-HSA-597592
Degradation of GLI2 by the proteasome R-HSA-5610783
Cellular response to hypoxia R-HSA-1234174
Cell Cycle Checkpoints R-HSA-69620
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of RAS by GAPs R-HSA-5658442
Regulation of PTEN stability and activity R-HSA-8948751
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RAF/MAP kinase cascade R-HSA-5673001
Apoptosis R-HSA-109581
Neutrophil degranulation R-HSA-6798695
G1/S Transition R-HSA-69206
RNA Polymerase II Transcription R-HSA-73857
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of RNA R-HSA-8953854
Intracellular signaling by second messengers R-HSA-9006925
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
G1/S DNA Damage Checkpoints R-HSA-69615
Stabilization of p53 R-HSA-69541
Signal Transduction R-HSA-162582
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Interleukin-1 signaling R-HSA-9020702
Assembly of the pre-replicative complex R-HSA-68867
FCERI mediated NF-kB activation R-HSA-2871837
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of GLI1 by the proteasome R-HSA-5610780
MAPK family signaling cascades R-HSA-5683057
Switching of origins to a post-replicative state R-HSA-69052
Degradation of DVL R-HSA-4641258
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of mitotic cell cycle R-HSA-453276
PIP3 activates AKT signaling R-HSA-1257604
Separation of Sister Chromatids R-HSA-2467813
Asymmetric localization of PCP proteins R-HSA-4608870
Mitotic Metaphase and Anaphase R-HSA-2555396
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
PTEN Regulation R-HSA-6807070
Programmed Cell Death R-HSA-5357801
Signaling by ROBO receptors R-HSA-376176
Signaling by NOTCH R-HSA-157118
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of RUNX2 expression and activity R-HSA-8939902
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Mitotic Anaphase R-HSA-68882
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic G2-G2/M phases R-HSA-453274
Metabolism R-HSA-1430728
Metabolism of polyamines R-HSA-351202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of Apoptosis R-HSA-169911
Degradation of AXIN R-HSA-4641257
Axon guidance R-HSA-422475
G2/M Transition R-HSA-69275
Defective CFTR causes cystic fibrosis R-HSA-5678895
C-type lectin receptors (CLRs) R-HSA-5621481
UCH proteinases R-HSA-5689603
Nervous system development R-HSA-9675108
Innate Immune System R-HSA-168249
Class I MHC mediated antigen processing & presentation R-HSA-983169
ER-Phagosome pathway R-HSA-1236974
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by Interleukins R-HSA-449147
p53-Dependent G1 DNA Damage Response R-HSA-69563
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream TCR signaling R-HSA-202424
Adaptive Immune System R-HSA-1280218
Beta-catenin independent WNT signaling R-HSA-3858494
TCR signaling R-HSA-202403
Interleukin-1 family signaling R-HSA-446652
DNA Replication R-HSA-69306
Generic Transcription Pathway R-HSA-212436
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of amino acids and derivatives R-HSA-71291
Gene expression (Transcription) R-HSA-74160
Hh mutants abrogate ligand secretion R-HSA-5387390
Antigen processing-Cross presentation R-HSA-1236975
Signaling by Hedgehog R-HSA-5358351
ABC transporter disorders R-HSA-5619084
p53-Independent DNA Damage Response R-HSA-69610
Cell Cycle, Mitotic R-HSA-69278
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Neddylation R-HSA-8951664
DNA Replication Pre-Initiation R-HSA-69002
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of RUNX3 expression and activity R-HSA-8941858
Negative regulation of NOTCH4 signaling R-HSA-9604323
ABC-family proteins mediated transport R-HSA-382556
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Immune System R-HSA-168256
PCP/CE pathway R-HSA-4086400
HIV Infection R-HSA-162906
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by WNT R-HSA-195721
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
M Phase R-HSA-68886
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX1 R-HSA-8878171
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism of proteins R-HSA-392499
MAPK1/MAPK3 signaling R-HSA-5684996
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of beta-catenin by the destruction complex R-HSA-195253
MAPK6/MAPK4 signaling R-HSA-5687128
Hedgehog 'on' state R-HSA-5632684
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle R-HSA-1640170
KEAP1-NFE2L2 pathway R-HSA-9755511
Cytokine Signaling in Immune system R-HSA-1280215
TCF dependent signaling in response to WNT R-HSA-201681
Synthesis of DNA R-HSA-69239
Hedgehog ligand biogenesis R-HSA-5358346
G2/M Checkpoints R-HSA-69481
Hedgehog 'off' state R-HSA-5610787
Activation of NF-kappaB in B cells R-HSA-1169091
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cellular responses to stress R-HSA-2262752
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Vpu mediated degradation of CD4 R-HSA-180534
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Host Interactions of HIV factors R-HSA-162909
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
S Phase R-HSA-69242
Degradation of GLI1 by the proteasome R-HSA-5610780
Hedgehog ligand biogenesis R-HSA-5358346
Synthesis of DNA R-HSA-69239
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
PIP3 activates AKT signaling R-HSA-1257604
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
Adaptive Immune System R-HSA-1280218
ABC-family proteins mediated transport R-HSA-382556
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Innate Immune System R-HSA-168249
Signaling by WNT R-HSA-195721
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cytokine Signaling in Immune system R-HSA-1280215
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic Metaphase and Anaphase R-HSA-2555396
Programmed Cell Death R-HSA-5357801
HIV Infection R-HSA-162906
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Apoptosis R-HSA-109581
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Intracellular signaling by second messengers R-HSA-9006925
Regulation of expression of SLITs and ROBOs R-HSA-9010553
UCH proteinases R-HSA-5689603
Signaling by Hedgehog R-HSA-5358351
Generic Transcription Pathway R-HSA-212436
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RAS by GAPs R-HSA-5658442
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream TCR signaling R-HSA-202424
Cellular responses to stimuli R-HSA-8953897
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism R-HSA-1430728
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Nervous system development R-HSA-9675108
Hh mutants are degraded by ERAD R-HSA-5362768
Orc1 removal from chromatin R-HSA-68949
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cellular response to hypoxia R-HSA-1234174
Hh mutants abrogate ligand secretion R-HSA-5387390
ER-Phagosome pathway R-HSA-1236974
Nuclear events mediated by NFE2L2 R-HSA-9759194
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of GLI2 by the proteasome R-HSA-5610783
Deubiquitination R-HSA-5688426
Mitotic G1 phase and G1/S transition R-HSA-453279
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by ROBO receptors R-HSA-376176
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by NOTCH R-HSA-157118
Regulation of PTEN stability and activity R-HSA-8948751
Cellular responses to stress R-HSA-2262752
Interleukin-1 signaling R-HSA-9020702
PCP/CE pathway R-HSA-4086400
Signal Transduction R-HSA-162582
Degradation of AXIN R-HSA-4641257
Transport of small molecules R-HSA-382551
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of beta-catenin by the destruction complex R-HSA-195253
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
M Phase R-HSA-68886
Neddylation R-HSA-8951664
Neutrophil degranulation R-HSA-6798695
RAF/MAP kinase cascade R-HSA-5673001
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Independent DNA Damage Response R-HSA-69610
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Post-translational protein modification R-HSA-597592
Host Interactions of HIV factors R-HSA-162909
G1/S Transition R-HSA-69206
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by Interleukins R-HSA-449147
MAPK6/MAPK4 signaling R-HSA-5687128
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Developmental Biology R-HSA-1266738
Metabolism of proteins R-HSA-392499
Transcriptional regulation by RUNX1 R-HSA-8878171
Cyclin E associated events during G1/S transition R-HSA-69202
Separation of Sister Chromatids R-HSA-2467813
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCR signaling R-HSA-202403
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
RNA Polymerase II Transcription R-HSA-73857
FCERI mediated NF-kB activation R-HSA-2871837
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of DVL R-HSA-4641258
Regulation of Apoptosis R-HSA-169911
MAPK family signaling cascades R-HSA-5683057
Transcriptional regulation by RUNX2 R-HSA-8878166
Disorders of transmembrane transporters R-HSA-5619115
Signaling by the B Cell Receptor (BCR) R-HSA-983705
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
G2/M Checkpoints R-HSA-69481
Immune System R-HSA-168256
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of amino acids and derivatives R-HSA-71291
Cellular response to chemical stress R-HSA-9711123
Mitotic Anaphase R-HSA-68882
G2/M Transition R-HSA-69275
Assembly of the pre-replicative complex R-HSA-68867
Signaling by NOTCH4 R-HSA-9013694
Stabilization of p53 R-HSA-69541
Beta-catenin independent WNT signaling R-HSA-3858494
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
C-type lectin receptors (CLRs) R-HSA-5621481
Disease R-HSA-1643685
Cell Cycle, Mitotic R-HSA-69278
Infectious disease R-HSA-5663205
TCF dependent signaling in response to WNT R-HSA-201681
DNA Replication R-HSA-69306
Regulation of mitotic cell cycle R-HSA-453276
Ub-specific processing proteases R-HSA-5689880
Hedgehog 'off' state R-HSA-5610787
Axon guidance R-HSA-422475
Negative regulation of NOTCH4 signaling R-HSA-9604323
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of polyamines R-HSA-351202
Antigen processing-Cross presentation R-HSA-1236975
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Switching of origins to a post-replicative state R-HSA-69052
Hedgehog 'on' state R-HSA-5632684
PTEN Regulation R-HSA-6807070
ABC transporter disorders R-HSA-5619084
Cell Cycle Checkpoints R-HSA-69620
Vpu mediated degradation of CD4 R-HSA-180534
S Phase R-HSA-69242
Metabolism of RNA R-HSA-8953854
G2/M Checkpoints R-HSA-69481
ABC transporter disorders R-HSA-5619084
Mitotic G1 phase and G1/S transition R-HSA-453279
Assembly of the pre-replicative complex R-HSA-68867
Activation of NF-kappaB in B cells R-HSA-1169091
DNA Replication R-HSA-69306
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Host Interactions of HIV factors R-HSA-162909
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Disorders of transmembrane transporters R-HSA-5619115
Degradation of AXIN R-HSA-4641257
ER-Phagosome pathway R-HSA-1236974
Degradation of GLI2 by the proteasome R-HSA-5610783
Negative regulation of NOTCH4 signaling R-HSA-9604323
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
RAF/MAP kinase cascade R-HSA-5673001
Vpu mediated degradation of CD4 R-HSA-180534
Cellular responses to stress R-HSA-2262752
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Generic Transcription Pathway R-HSA-212436
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G1/S Transition R-HSA-69206
Developmental Biology R-HSA-1266738
G2/M Transition R-HSA-69275
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by NOTCH R-HSA-157118
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog 'off' state R-HSA-5610787
Regulation of RAS by GAPs R-HSA-5658442
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by NOTCH4 R-HSA-9013694
Antigen processing-Cross presentation R-HSA-1236975
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cyclin E associated events during G1/S transition R-HSA-69202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Ub-specific processing proteases R-HSA-5689880
Hedgehog 'on' state R-HSA-5632684
Downstream TCR signaling R-HSA-202424
S Phase R-HSA-69242
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cellular response to hypoxia R-HSA-1234174
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
FCERI mediated NF-kB activation R-HSA-2871837
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Interleukin-1 signaling R-HSA-9020702
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of polyamines R-HSA-351202
PIP3 activates AKT signaling R-HSA-1257604
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cell Cycle, Mitotic R-HSA-69278
Metabolism of proteins R-HSA-392499
Separation of Sister Chromatids R-HSA-2467813
Disease R-HSA-1643685
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular responses to stimuli R-HSA-8953897
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Axon guidance R-HSA-422475
Innate Immune System R-HSA-168249
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
ABC-family proteins mediated transport R-HSA-382556
Transcriptional regulation by RUNX1 R-HSA-8878171
Synthesis of DNA R-HSA-69239
Nervous system development R-HSA-9675108
Signaling by ROBO receptors R-HSA-376176
Degradation of DVL R-HSA-4641258
Switching of origins to a post-replicative state R-HSA-69052
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of RUNX3 expression and activity R-HSA-8941858
Apoptosis R-HSA-109581
DNA Replication Pre-Initiation R-HSA-69002
NIK-->noncanonical NF-kB signaling R-HSA-5676590
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism R-HSA-1430728
UCH proteinases R-HSA-5689603
Regulation of expression of SLITs and ROBOs R-HSA-9010553
TCR signaling R-HSA-202403
Hedgehog ligand biogenesis R-HSA-5358346
MAPK family signaling cascades R-HSA-5683057
Neddylation R-HSA-8951664
KEAP1-NFE2L2 pathway R-HSA-9755511
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Adaptive Immune System R-HSA-1280218
Asymmetric localization of PCP proteins R-HSA-4608870
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Neutrophil degranulation R-HSA-6798695
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transcriptional regulation by RUNX3 R-HSA-8878159
Interleukin-1 family signaling R-HSA-446652
Cell Cycle R-HSA-1640170
Mitotic G2-G2/M phases R-HSA-453274
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by WNT R-HSA-195721
C-type lectin receptors (CLRs) R-HSA-5621481
HIV Infection R-HSA-162906
Transport of small molecules R-HSA-382551
Signaling by Interleukins R-HSA-449147
Regulation of Apoptosis R-HSA-169911
Signaling by Hedgehog R-HSA-5358351
Stabilization of p53 R-HSA-69541
Metabolism of amino acids and derivatives R-HSA-71291
TCF dependent signaling in response to WNT R-HSA-201681
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Orc1 removal from chromatin R-HSA-68949
Signal Transduction R-HSA-162582
Metabolism of RNA R-HSA-8953854
Intracellular signaling by second messengers R-HSA-9006925
RNA Polymerase II Transcription R-HSA-73857
Mitotic Anaphase R-HSA-68882
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of mitotic cell cycle R-HSA-453276
Post-translational protein modification R-HSA-597592
Cell Cycle Checkpoints R-HSA-69620
Deubiquitination R-HSA-5688426
PCP/CE pathway R-HSA-4086400
Regulation of RUNX2 expression and activity R-HSA-8939902
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular response to chemical stress R-HSA-9711123
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
PTEN Regulation R-HSA-6807070
Hh mutants are degraded by ERAD R-HSA-5362768
Infectious disease R-HSA-5663205
Nuclear events mediated by NFE2L2 R-HSA-9759194
M Phase R-HSA-68886
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Immune System R-HSA-168256
Hh mutants abrogate ligand secretion R-HSA-5387390
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
p53-Independent DNA Damage Response R-HSA-69610
Defective CFTR causes cystic fibrosis R-HSA-5678895
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Dependent G1 DNA Damage Response R-HSA-69563
TCF dependent signaling in response to WNT R-HSA-201681
Cell Cycle Checkpoints R-HSA-69620
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transport of small molecules R-HSA-382551
Signaling by NOTCH4 R-HSA-9013694
Assembly of the pre-replicative complex R-HSA-68867
Programmed Cell Death R-HSA-5357801
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by Interleukins R-HSA-449147
Cellular responses to stimuli R-HSA-8953897
Axon guidance R-HSA-422475
Metabolism of RNA R-HSA-8953854
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Transcriptional regulation by RUNX2 R-HSA-8878166
Developmental Biology R-HSA-1266738
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
HIV Infection R-HSA-162906
Hedgehog 'off' state R-HSA-5610787
Interleukin-1 family signaling R-HSA-446652
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of RAS by GAPs R-HSA-5658442
Mitotic G2-G2/M phases R-HSA-453274
Signaling by ROBO receptors R-HSA-376176
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cellular response to chemical stress R-HSA-9711123
G2/M Checkpoints R-HSA-69481
Switching of origins to a post-replicative state R-HSA-69052
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of GLI2 by the proteasome R-HSA-5610783
RAF/MAP kinase cascade R-HSA-5673001
PIP3 activates AKT signaling R-HSA-1257604
Cellular responses to stress R-HSA-2262752
ABC-family proteins mediated transport R-HSA-382556
Regulation of mitotic cell cycle R-HSA-453276
PCP/CE pathway R-HSA-4086400
Ub-specific processing proteases R-HSA-5689880
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Independent DNA Damage Response R-HSA-69610
DNA Replication Pre-Initiation R-HSA-69002
Signal Transduction R-HSA-162582
Regulation of PTEN stability and activity R-HSA-8948751
Cell Cycle R-HSA-1640170
Degradation of AXIN R-HSA-4641257
DNA Replication R-HSA-69306
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of Apoptosis R-HSA-169911
Signaling by WNT R-HSA-195721
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX1 R-HSA-8878171
Metabolism of proteins R-HSA-392499
Immune System R-HSA-168256
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of RUNX2 expression and activity R-HSA-8939902
Mitotic Metaphase and Anaphase R-HSA-2555396
Cyclin E associated events during G1/S transition R-HSA-69202
Synthesis of DNA R-HSA-69239
ER-Phagosome pathway R-HSA-1236974
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by NOTCH R-HSA-157118
Regulation of RUNX3 expression and activity R-HSA-8941858
Neutrophil degranulation R-HSA-6798695
C-type lectin receptors (CLRs) R-HSA-5621481
Cellular response to hypoxia R-HSA-1234174
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Infectious disease R-HSA-5663205
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G1 phase and G1/S transition R-HSA-453279
UCH proteinases R-HSA-5689603
Adaptive Immune System R-HSA-1280218
Vpu mediated degradation of CD4 R-HSA-180534
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
KEAP1-NFE2L2 pathway R-HSA-9755511
Antigen processing-Cross presentation R-HSA-1236975
Hedgehog 'on' state R-HSA-5632684
Cell Cycle, Mitotic R-HSA-69278
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Negative regulation of NOTCH4 signaling R-HSA-9604323
Nervous system development R-HSA-9675108
Gene expression (Transcription) R-HSA-74160
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RNA Polymerase II Transcription R-HSA-73857
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Orc1 removal from chromatin R-HSA-68949
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of amino acids and derivatives R-HSA-71291
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Post-translational protein modification R-HSA-597592
MAPK family signaling cascades R-HSA-5683057
PTEN Regulation R-HSA-6807070
Stabilization of p53 R-HSA-69541
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
S Phase R-HSA-69242
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by the B Cell Receptor (BCR) R-HSA-983705
CLEC7A (Dectin-1) signaling R-HSA-5607764
Innate Immune System R-HSA-168249
G1/S Transition R-HSA-69206
Metabolism of polyamines R-HSA-351202
Host Interactions of HIV factors R-HSA-162909
MAPK1/MAPK3 signaling R-HSA-5684996
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G2/M Transition R-HSA-69275
Downstream TCR signaling R-HSA-202424
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Vif-mediated degradation of APOBEC3G R-HSA-180585
Asymmetric localization of PCP proteins R-HSA-4608870
Transcriptional regulation by RUNX3 R-HSA-8878159
Degradation of GLI1 by the proteasome R-HSA-5610780
Separation of Sister Chromatids R-HSA-2467813
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Class I MHC mediated antigen processing & presentation R-HSA-983169
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Degradation of DVL R-HSA-4641258
Apoptosis R-HSA-109581
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hh mutants are degraded by ERAD R-HSA-5362768
Nuclear events mediated by NFE2L2 R-HSA-9759194
TCR signaling R-HSA-202403
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
M Phase R-HSA-68886
Interleukin-1 signaling R-HSA-9020702
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Deubiquitination R-HSA-5688426
Metabolism R-HSA-1430728
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Disease R-HSA-1643685
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Defective CFTR causes cystic fibrosis R-HSA-5678895
Mitotic Anaphase R-HSA-68882
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Neddylation R-HSA-8951664
ABC transporter disorders R-HSA-5619084
Disorders of transmembrane transporters R-HSA-5619115
Generic Transcription Pathway R-HSA-212436
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by Hedgehog R-HSA-5358351
MAPK1/MAPK3 signaling R-HSA-5684996
Infectious disease R-HSA-5663205
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Switching of origins to a post-replicative state R-HSA-69052
DNA Replication R-HSA-69306
Antigen processing-Cross presentation R-HSA-1236975
Beta-catenin independent WNT signaling R-HSA-3858494
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of RAS by GAPs R-HSA-5658442
Cellular response to chemical stress R-HSA-9711123
p53-Dependent G1 DNA Damage Response R-HSA-69563
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cell Cycle R-HSA-1640170
Stabilization of p53 R-HSA-69541
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of proteins R-HSA-392499
Neddylation R-HSA-8951664
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Mitotic G1 phase and G1/S transition R-HSA-453279
Signal Transduction R-HSA-162582
G2/M Transition R-HSA-69275
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Degradation of GLI1 by the proteasome R-HSA-5610780
Deubiquitination R-HSA-5688426
Host Interactions of HIV factors R-HSA-162909
Apoptosis R-HSA-109581
Ub-specific processing proteases R-HSA-5689880
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 signaling R-HSA-9020702
G2/M Checkpoints R-HSA-69481
Signaling by Interleukins R-HSA-449147
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
HIV Infection R-HSA-162906
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Downstream TCR signaling R-HSA-202424
C-type lectin receptors (CLRs) R-HSA-5621481
FCERI mediated NF-kB activation R-HSA-2871837
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic Anaphase R-HSA-68882
Cellular response to hypoxia R-HSA-1234174
Cyclin E associated events during G1/S transition R-HSA-69202
Innate Immune System R-HSA-168249
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of RUNX2 expression and activity R-HSA-8939902
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
Neutrophil degranulation R-HSA-6798695
Regulation of PTEN stability and activity R-HSA-8948751
Cellular responses to stimuli R-HSA-8953897
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of Apoptosis R-HSA-169911
PIP3 activates AKT signaling R-HSA-1257604
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism R-HSA-1430728
Separation of Sister Chromatids R-HSA-2467813
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
MAPK family signaling cascades R-HSA-5683057
Degradation of beta-catenin by the destruction complex R-HSA-195253
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Orc1 removal from chromatin R-HSA-68949
Regulation of mitotic cell cycle R-HSA-453276
Developmental Biology R-HSA-1266738
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX3 R-HSA-8878159
G1/S DNA Damage Checkpoints R-HSA-69615
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
DNA Replication Pre-Initiation R-HSA-69002
ABC-family proteins mediated transport R-HSA-382556
Signaling by WNT R-HSA-195721
Interleukin-1 family signaling R-HSA-446652
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
ER-Phagosome pathway R-HSA-1236974
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Negative regulation of NOTCH4 signaling R-HSA-9604323
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of DVL R-HSA-4641258
RNA Polymerase II Transcription R-HSA-73857
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by Hedgehog R-HSA-5358351
Immune System R-HSA-168256
Synthesis of DNA R-HSA-69239
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of AXIN R-HSA-4641257
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hedgehog ligand biogenesis R-HSA-5358346
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transport of small molecules R-HSA-382551
Intracellular signaling by second messengers R-HSA-9006925
Signaling by ROBO receptors R-HSA-376176
Generic Transcription Pathway R-HSA-212436
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of expression of SLITs and ROBOs R-HSA-9010553
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Axon guidance R-HSA-422475
Cell Cycle Checkpoints R-HSA-69620
Defective CFTR causes cystic fibrosis R-HSA-5678895
Disorders of transmembrane transporters R-HSA-5619115
Programmed Cell Death R-HSA-5357801
Hedgehog 'on' state R-HSA-5632684
Vpu mediated degradation of CD4 R-HSA-180534
PTEN Regulation R-HSA-6807070
Transcriptional regulation by RUNX1 R-HSA-8878171
Activation of NF-kappaB in B cells R-HSA-1169091
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
RAF/MAP kinase cascade R-HSA-5673001
Regulation of RUNX3 expression and activity R-HSA-8941858
Mitotic Metaphase and Anaphase R-HSA-2555396
KEAP1-NFE2L2 pathway R-HSA-9755511
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of polyamines R-HSA-351202
TCR signaling R-HSA-202403
UCH proteinases R-HSA-5689603
Disease R-HSA-1643685
S Phase R-HSA-69242
Assembly of the pre-replicative complex R-HSA-68867
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by NOTCH4 R-HSA-9013694
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
M Phase R-HSA-68886
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Adaptive Immune System R-HSA-1280218
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog 'off' state R-HSA-5610787
Cell Cycle, Mitotic R-HSA-69278
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Nuclear events mediated by NFE2L2 R-HSA-9759194
PCP/CE pathway R-HSA-4086400
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Vif-mediated degradation of APOBEC3G R-HSA-180585
Metabolism of RNA R-HSA-8953854
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by NOTCH R-HSA-157118
Mitotic G2-G2/M phases R-HSA-453274
Cellular responses to stress R-HSA-2262752
Nervous system development R-HSA-9675108
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
FCERI mediated NF-kB activation R-HSA-2871837
TCF dependent signaling in response to WNT R-HSA-201681
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
M Phase R-HSA-68886
Regulation of RUNX2 expression and activity R-HSA-8939902
Ub-specific processing proteases R-HSA-5689880
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Apoptosis R-HSA-109581
TCR signaling R-HSA-202403
Neutrophil degranulation R-HSA-6798695
Defective CFTR causes cystic fibrosis R-HSA-5678895
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G1/S Transition R-HSA-69206
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Asymmetric localization of PCP proteins R-HSA-4608870
Degradation of GLI2 by the proteasome R-HSA-5610783
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of RNA R-HSA-8953854
MAPK family signaling cascades R-HSA-5683057
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Downstream TCR signaling R-HSA-202424
Regulation of Apoptosis R-HSA-169911
Cellular responses to stress R-HSA-2262752
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
C-type lectin receptors (CLRs) R-HSA-5621481
Activation of NF-kappaB in B cells R-HSA-1169091
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Degradation of AXIN R-HSA-4641257
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
DNA Replication Pre-Initiation R-HSA-69002
G1/S DNA Damage Checkpoints R-HSA-69615
Mitotic G2-G2/M phases R-HSA-453274
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RAS by GAPs R-HSA-5658442
Programmed Cell Death R-HSA-5357801
Metabolism of proteins R-HSA-392499
PIP3 activates AKT signaling R-HSA-1257604
Signaling by WNT R-HSA-195721
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
DNA Replication R-HSA-69306
ER-Phagosome pathway R-HSA-1236974
Infectious disease R-HSA-5663205
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle, Mitotic R-HSA-69278
Disorders of transmembrane transporters R-HSA-5619115
Transcriptional regulation by RUNX1 R-HSA-8878171
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hedgehog 'on' state R-HSA-5632684
Antigen processing-Cross presentation R-HSA-1236975
Signaling by ROBO receptors R-HSA-376176
p53-Independent DNA Damage Response R-HSA-69610
UCH proteinases R-HSA-5689603
Degradation of DVL R-HSA-4641258
Signaling by NOTCH R-HSA-157118
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
CLEC7A (Dectin-1) signaling R-HSA-5607764
HIV Infection R-HSA-162906
PCP/CE pathway R-HSA-4086400
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of polyamines R-HSA-351202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Axon guidance R-HSA-422475
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Interleukin-1 signaling R-HSA-9020702
Hedgehog ligand biogenesis R-HSA-5358346
MAPK6/MAPK4 signaling R-HSA-5687128
G2/M Transition R-HSA-69275
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 family signaling R-HSA-446652
Developmental Biology R-HSA-1266738
Mitotic Anaphase R-HSA-68882
Cellular response to hypoxia R-HSA-1234174
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
G2/M Checkpoints R-HSA-69481
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by NOTCH4 R-HSA-9013694
Vif-mediated degradation of APOBEC3G R-HSA-180585
Separation of Sister Chromatids R-HSA-2467813
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Beta-catenin independent WNT signaling R-HSA-3858494
p53-Dependent G1 DNA Damage Response R-HSA-69563
ABC transporter disorders R-HSA-5619084
Switching of origins to a post-replicative state R-HSA-69052
Transcriptional regulation by RUNX2 R-HSA-8878166
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular responses to stimuli R-HSA-8953897
Synthesis of DNA R-HSA-69239
Regulation of PTEN stability and activity R-HSA-8948751
Transport of small molecules R-HSA-382551
Regulation of mitotic cell cycle R-HSA-453276
ABC-family proteins mediated transport R-HSA-382556
Generic Transcription Pathway R-HSA-212436
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cyclin E associated events during G1/S transition R-HSA-69202
Gene expression (Transcription) R-HSA-74160
Negative regulation of NOTCH4 signaling R-HSA-9604323
Assembly of the pre-replicative complex R-HSA-68867
PTEN Regulation R-HSA-6807070
Nervous system development R-HSA-9675108
S Phase R-HSA-69242
Immune System R-HSA-168256
Metabolism of amino acids and derivatives R-HSA-71291
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of GLI1 by the proteasome R-HSA-5610780
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Adaptive Immune System R-HSA-1280218
Cell Cycle R-HSA-1640170
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signal Transduction R-HSA-162582
Neddylation R-HSA-8951664
Vpu mediated degradation of CD4 R-HSA-180534
Hh mutants abrogate ligand secretion R-HSA-5387390
Post-translational protein modification R-HSA-597592
Signaling by Interleukins R-HSA-449147
Hedgehog 'off' state R-HSA-5610787
Cellular response to chemical stress R-HSA-9711123
Signaling by Hedgehog R-HSA-5358351
Innate Immune System R-HSA-168249
Host Interactions of HIV factors R-HSA-162909
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RNA Polymerase II Transcription R-HSA-73857
Metabolism R-HSA-1430728
Deubiquitination R-HSA-5688426
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Intracellular signaling by second messengers R-HSA-9006925
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Stabilization of p53 R-HSA-69541
Regulation of RUNX3 expression and activity R-HSA-8941858
Mitotic Metaphase and Anaphase R-HSA-2555396
RAF/MAP kinase cascade R-HSA-5673001
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Hh mutants are degraded by ERAD R-HSA-5362768
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular response to chemical stress R-HSA-9711123
Hedgehog 'on' state R-HSA-5632684
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
RAF/MAP kinase cascade R-HSA-5673001
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by NOTCH4 R-HSA-9013694
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
MAPK1/MAPK3 signaling R-HSA-5684996
Antigen processing-Cross presentation R-HSA-1236975
Mitotic Metaphase and Anaphase R-HSA-2555396
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by ROBO receptors R-HSA-376176
Apoptosis R-HSA-109581
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of AXIN R-HSA-4641257
MAPK family signaling cascades R-HSA-5683057
ABC transporter disorders R-HSA-5619084
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signal Transduction R-HSA-162582
Nervous system development R-HSA-9675108
Post-translational protein modification R-HSA-597592
ER-Phagosome pathway R-HSA-1236974
Defective CFTR causes cystic fibrosis R-HSA-5678895
PCP/CE pathway R-HSA-4086400
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Adaptive Immune System R-HSA-1280218
Axon guidance R-HSA-422475
Generic Transcription Pathway R-HSA-212436
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of PTEN stability and activity R-HSA-8948751
Ub-specific processing proteases R-HSA-5689880
Developmental Biology R-HSA-1266738
p53-Dependent G1 DNA Damage Response R-HSA-69563
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of GLI2 by the proteasome R-HSA-5610783
Assembly of the pre-replicative complex R-HSA-68867
Interleukin-1 family signaling R-HSA-446652
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
FCERI mediated NF-kB activation R-HSA-2871837
Innate Immune System R-HSA-168249
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular response to hypoxia R-HSA-1234174
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism of proteins R-HSA-392499
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Intracellular signaling by second messengers R-HSA-9006925
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Vpu mediated degradation of CD4 R-HSA-180534
Synthesis of DNA R-HSA-69239
Hh mutants abrogate ligand secretion R-HSA-5387390
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by Interleukins R-HSA-449147
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of Apoptosis R-HSA-169911
Programmed Cell Death R-HSA-5357801
PTEN Regulation R-HSA-6807070
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RNA Polymerase II Transcription R-HSA-73857
Negative regulation of NOTCH4 signaling R-HSA-9604323
HIV Infection R-HSA-162906
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cell Cycle, Mitotic R-HSA-69278
Disease R-HSA-1643685
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RAS by GAPs R-HSA-5658442
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX3 expression and activity R-HSA-8941858
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Downstream TCR signaling R-HSA-202424
Cell Cycle R-HSA-1640170
Deubiquitination R-HSA-5688426
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
ABC-family proteins mediated transport R-HSA-382556
KEAP1-NFE2L2 pathway R-HSA-9755511
Immune System R-HSA-168256
S Phase R-HSA-69242
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hedgehog ligand biogenesis R-HSA-5358346
Neddylation R-HSA-8951664
Signaling by NOTCH R-HSA-157118
Cytokine Signaling in Immune system R-HSA-1280215
TCF dependent signaling in response to WNT R-HSA-201681
Asymmetric localization of PCP proteins R-HSA-4608870
M Phase R-HSA-68886
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of RNA R-HSA-8953854
Cell Cycle Checkpoints R-HSA-69620
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular responses to stress R-HSA-2262752
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of RUNX2 expression and activity R-HSA-8939902
NIK-->noncanonical NF-kB signaling R-HSA-5676590
p53-Independent DNA Damage Response R-HSA-69610
Signaling by WNT R-HSA-195721
CLEC7A (Dectin-1) signaling R-HSA-5607764
Transport of small molecules R-HSA-382551
Transcriptional regulation by RUNX1 R-HSA-8878171
Transcriptional regulation by RUNX3 R-HSA-8878159
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by Hedgehog R-HSA-5358351
Stabilization of p53 R-HSA-69541
G1/S DNA Damage Checkpoints R-HSA-69615
Mitotic Anaphase R-HSA-68882
Degradation of DVL R-HSA-4641258
G1/S Transition R-HSA-69206
Regulation of mitotic cell cycle R-HSA-453276
DNA Replication Pre-Initiation R-HSA-69002
Infectious disease R-HSA-5663205
Degradation of beta-catenin by the destruction complex R-HSA-195253
Host Interactions of HIV factors R-HSA-162909
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Switching of origins to a post-replicative state R-HSA-69052
Orc1 removal from chromatin R-HSA-68949
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Mitotic G1 phase and G1/S transition R-HSA-453279
Neutrophil degranulation R-HSA-6798695
Gene expression (Transcription) R-HSA-74160
Disorders of transmembrane transporters R-HSA-5619115
Metabolism R-HSA-1430728
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Separation of Sister Chromatids R-HSA-2467813
Cellular responses to stimuli R-HSA-8953897
Metabolism of polyamines R-HSA-351202
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
TCR signaling R-HSA-202403
Hedgehog 'off' state R-HSA-5610787
G2/M Checkpoints R-HSA-69481
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
UCH proteinases R-HSA-5689603
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cyclin E associated events during G1/S transition R-HSA-69202
DNA Replication R-HSA-69306
PIP3 activates AKT signaling R-HSA-1257604
Interleukin-1 signaling R-HSA-9020702
G2/M Transition R-HSA-69275
Cell Cycle, Mitotic R-HSA-69278
Beta-catenin independent WNT signaling R-HSA-3858494
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RUNX3 expression and activity R-HSA-8941858
Apoptosis R-HSA-109581
Metabolism of polyamines R-HSA-351202
G2/M Transition R-HSA-69275
Degradation of AXIN R-HSA-4641257
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Deubiquitination R-HSA-5688426
CLEC7A (Dectin-1) signaling R-HSA-5607764
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Dependent G1 DNA Damage Response R-HSA-69563
Generic Transcription Pathway R-HSA-212436
Nuclear events mediated by NFE2L2 R-HSA-9759194
Immune System R-HSA-168256
Nervous system development R-HSA-9675108
Orc1 removal from chromatin R-HSA-68949
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by NOTCH4 R-HSA-9013694
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by WNT R-HSA-195721
Stabilization of p53 R-HSA-69541
Vpu mediated degradation of CD4 R-HSA-180534
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular response to hypoxia R-HSA-1234174
Downstream TCR signaling R-HSA-202424
ABC transporter disorders R-HSA-5619084
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular responses to stimuli R-HSA-8953897
Axon guidance R-HSA-422475
TCR signaling R-HSA-202403
Assembly of the pre-replicative complex R-HSA-68867
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Vif-mediated degradation of APOBEC3G R-HSA-180585
G1/S Transition R-HSA-69206
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Intracellular signaling by second messengers R-HSA-9006925
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX3 R-HSA-8878159
G2/M Checkpoints R-HSA-69481
RNA Polymerase II Transcription R-HSA-73857
Disease R-HSA-1643685
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Class I MHC mediated antigen processing & presentation R-HSA-983169
Defective CFTR causes cystic fibrosis R-HSA-5678895
PIP3 activates AKT signaling R-HSA-1257604
Cell Cycle R-HSA-1640170
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of GLI1 by the proteasome R-HSA-5610780
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
UCH proteinases R-HSA-5689603
Metabolism R-HSA-1430728
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX2 R-HSA-8878166
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by ROBO receptors R-HSA-376176
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog 'off' state R-HSA-5610787
Hedgehog 'on' state R-HSA-5632684
Ub-specific processing proteases R-HSA-5689880
Asymmetric localization of PCP proteins R-HSA-4608870
DNA Replication R-HSA-69306
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of RNA R-HSA-8953854
Innate Immune System R-HSA-168249
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by Hedgehog R-HSA-5358351
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of proteins R-HSA-392499
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
Regulation of Apoptosis R-HSA-169911
Degradation of DVL R-HSA-4641258
Regulation of RUNX2 expression and activity R-HSA-8939902
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Antigen processing-Cross presentation R-HSA-1236975
C-type lectin receptors (CLRs) R-HSA-5621481
Developmental Biology R-HSA-1266738
RAF/MAP kinase cascade R-HSA-5673001
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Neddylation R-HSA-8951664
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interleukin-1 signaling R-HSA-9020702
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic G2-G2/M phases R-HSA-453274
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle Checkpoints R-HSA-69620
Transcriptional regulation by RUNX1 R-HSA-8878171
Switching of origins to a post-replicative state R-HSA-69052
Host Interactions of HIV factors R-HSA-162909
ER-Phagosome pathway R-HSA-1236974
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Degradation of beta-catenin by the destruction complex R-HSA-195253
Disorders of transmembrane transporters R-HSA-5619115
Degradation of GLI2 by the proteasome R-HSA-5610783
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PCP/CE pathway R-HSA-4086400
Signaling by NOTCH R-HSA-157118
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hh mutants abrogate ligand secretion R-HSA-5387390
ABC-family proteins mediated transport R-HSA-382556
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of mitotic cell cycle R-HSA-453276
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of PTEN stability and activity R-HSA-8948751
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by Interleukins R-HSA-449147
M Phase R-HSA-68886
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Replication Pre-Initiation R-HSA-69002
Mitotic Anaphase R-HSA-68882
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic Metaphase and Anaphase R-HSA-2555396
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
PTEN Regulation R-HSA-6807070
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stress R-HSA-2262752
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK6/MAPK4 signaling R-HSA-5687128
FCERI mediated NF-kB activation R-HSA-2871837
Post-translational protein modification R-HSA-597592
Interleukin-1 family signaling R-HSA-446652
Programmed Cell Death R-HSA-5357801
p53-Independent DNA Damage Response R-HSA-69610
Synthesis of DNA R-HSA-69239
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Adaptive Immune System R-HSA-1280218
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Neutrophil degranulation R-HSA-6798695
S Phase R-HSA-69242
Separation of Sister Chromatids R-HSA-2467813
HIV Infection R-HSA-162906
Transport of small molecules R-HSA-382551
Mitotic G1 phase and G1/S transition R-HSA-453279
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular response to chemical stress R-HSA-9711123
Neutrophil degranulation R-HSA-6798695
Regulation of RUNX2 expression and activity R-HSA-8939902
Mitotic G1 phase and G1/S transition R-HSA-453279
ABC-family proteins mediated transport R-HSA-382556
Hh mutants abrogate ligand secretion R-HSA-5387390
Vpu mediated degradation of CD4 R-HSA-180534
Metabolism of amino acids and derivatives R-HSA-71291
Nervous system development R-HSA-9675108
Regulation of RUNX3 expression and activity R-HSA-8941858
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of beta-catenin by the destruction complex R-HSA-195253
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Independent DNA Damage Response R-HSA-69610
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
KEAP1-NFE2L2 pathway R-HSA-9755511
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by ROBO receptors R-HSA-376176
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of proteins R-HSA-392499
Disorders of transmembrane transporters R-HSA-5619115
TCF dependent signaling in response to WNT R-HSA-201681
Antigen processing-Cross presentation R-HSA-1236975
Switching of origins to a post-replicative state R-HSA-69052
Cellular responses to stimuli R-HSA-8953897
Host Interactions of HIV factors R-HSA-162909
Hedgehog ligand biogenesis R-HSA-5358346
Developmental Biology R-HSA-1266738
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Gene expression (Transcription) R-HSA-74160
Mitotic Anaphase R-HSA-68882
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic Metaphase and Anaphase R-HSA-2555396
Neddylation R-HSA-8951664
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of DVL R-HSA-4641258
Interleukin-1 family signaling R-HSA-446652
Transcriptional regulation by RUNX3 R-HSA-8878159
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Intracellular signaling by second messengers R-HSA-9006925
Interleukin-1 signaling R-HSA-9020702
G1/S DNA Damage Checkpoints R-HSA-69615
MAPK family signaling cascades R-HSA-5683057
Signaling by NOTCH R-HSA-157118
Cellular response to hypoxia R-HSA-1234174
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of RAS by GAPs R-HSA-5658442
Negative regulation of NOTCH4 signaling R-HSA-9604323
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle R-HSA-1640170
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of AXIN R-HSA-4641257
Degradation of GLI1 by the proteasome R-HSA-5610780
UCH proteinases R-HSA-5689603
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
G1/S Transition R-HSA-69206
C-type lectin receptors (CLRs) R-HSA-5621481
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ub-specific processing proteases R-HSA-5689880
Signaling by WNT R-HSA-195721
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by Hedgehog R-HSA-5358351
ER-Phagosome pathway R-HSA-1236974
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
Downstream TCR signaling R-HSA-202424
Nuclear events mediated by NFE2L2 R-HSA-9759194
Transcriptional regulation by RUNX1 R-HSA-8878171
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Axon guidance R-HSA-422475
Synthesis of DNA R-HSA-69239
PTEN Regulation R-HSA-6807070
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
DNA Replication Pre-Initiation R-HSA-69002
Cellular responses to stress R-HSA-2262752
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PIP3 activates AKT signaling R-HSA-1257604
Deubiquitination R-HSA-5688426
G2/M Transition R-HSA-69275
Stabilization of p53 R-HSA-69541
Metabolism of RNA R-HSA-8953854
HIV Infection R-HSA-162906
Apoptosis R-HSA-109581
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Interleukins R-HSA-449147
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Post-translational protein modification R-HSA-597592
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of PTEN stability and activity R-HSA-8948751
Hh mutants are degraded by ERAD R-HSA-5362768
Adaptive Immune System R-HSA-1280218
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hedgehog 'off' state R-HSA-5610787
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of polyamines R-HSA-351202
Transport of small molecules R-HSA-382551
Regulation of expression of SLITs and ROBOs R-HSA-9010553
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Innate Immune System R-HSA-168249
DNA Replication R-HSA-69306
TCR signaling R-HSA-202403
MAPK6/MAPK4 signaling R-HSA-5687128
Immune System R-HSA-168256
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
Metabolism R-HSA-1430728
Degradation of GLI2 by the proteasome R-HSA-5610783
Cell Cycle Checkpoints R-HSA-69620
Signaling by NOTCH4 R-HSA-9013694
RNA Polymerase II Transcription R-HSA-73857
S Phase R-HSA-69242
Cell Cycle, Mitotic R-HSA-69278
RAF/MAP kinase cascade R-HSA-5673001
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
G2/M Checkpoints R-HSA-69481
Cellular response to chemical stress R-HSA-9711123
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic G2-G2/M phases R-HSA-453274
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
Defective CFTR causes cystic fibrosis R-HSA-5678895
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Hedgehog 'on' state R-HSA-5632684
Activation of NF-kappaB in B cells R-HSA-1169091
PCP/CE pathway R-HSA-4086400
Orc1 removal from chromatin R-HSA-68949
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of Apoptosis R-HSA-169911
Metabolism R-HSA-1430728
Transport of small molecules R-HSA-382551
MAPK family signaling cascades R-HSA-5683057
Signaling by WNT R-HSA-195721
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hh mutants abrogate ligand secretion R-HSA-5387390
Infectious disease R-HSA-5663205
Degradation of AXIN R-HSA-4641257
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Axon guidance R-HSA-422475
Adaptive Immune System R-HSA-1280218
KEAP1-NFE2L2 pathway R-HSA-9755511
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Asymmetric localization of PCP proteins R-HSA-4608870
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Activation of NF-kappaB in B cells R-HSA-1169091
Apoptosis R-HSA-109581
Signaling by ROBO receptors R-HSA-376176
Developmental Biology R-HSA-1266738
Signaling by NOTCH4 R-HSA-9013694
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of mitotic cell cycle R-HSA-453276
Regulation of PTEN stability and activity R-HSA-8948751
Generic Transcription Pathway R-HSA-212436
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cellular response to hypoxia R-HSA-1234174
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Hedgehog 'on' state R-HSA-5632684
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Separation of Sister Chromatids R-HSA-2467813
p53-Independent DNA Damage Response R-HSA-69610
Innate Immune System R-HSA-168249
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX1 R-HSA-8878171
RNA Polymerase II Transcription R-HSA-73857
Metabolism of proteins R-HSA-392499
Degradation of GLI1 by the proteasome R-HSA-5610780
PIP3 activates AKT signaling R-HSA-1257604
Mitotic G1 phase and G1/S transition R-HSA-453279
PCP/CE pathway R-HSA-4086400
TCR signaling R-HSA-202403
Metabolism of amino acids and derivatives R-HSA-71291
Ub-specific processing proteases R-HSA-5689880
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Class I MHC mediated antigen processing & presentation R-HSA-983169
ER-Phagosome pathway R-HSA-1236974
Synthesis of DNA R-HSA-69239
Assembly of the pre-replicative complex R-HSA-68867
Host Interactions of HIV factors R-HSA-162909
Degradation of DVL R-HSA-4641258
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
ABC-family proteins mediated transport R-HSA-382556
PTEN Regulation R-HSA-6807070
Signal Transduction R-HSA-162582
Nuclear events mediated by NFE2L2 R-HSA-9759194
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of Apoptosis R-HSA-169911
Downstream TCR signaling R-HSA-202424
M Phase R-HSA-68886
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Negative regulation of NOTCH4 signaling R-HSA-9604323
G2/M Checkpoints R-HSA-69481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cell Cycle, Mitotic R-HSA-69278
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Deubiquitination R-HSA-5688426
Degradation of beta-catenin by the destruction complex R-HSA-195253
Metabolism of polyamines R-HSA-351202
Signaling by Interleukins R-HSA-449147
TCF dependent signaling in response to WNT R-HSA-201681
Disease R-HSA-1643685
Nervous system development R-HSA-9675108
DNA Replication Pre-Initiation R-HSA-69002
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX2 R-HSA-8878166
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
G1/S Transition R-HSA-69206
Regulation of RAS by GAPs R-HSA-5658442
G2/M Transition R-HSA-69275
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Dependent G1 DNA Damage Response R-HSA-69563
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog ligand biogenesis R-HSA-5358346
UCH proteinases R-HSA-5689603
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH R-HSA-157118
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metabolism of RNA R-HSA-8953854
Mitotic G2-G2/M phases R-HSA-453274
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Neddylation R-HSA-8951664
Degradation of GLI2 by the proteasome R-HSA-5610783
Mitotic Anaphase R-HSA-68882
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of RUNX3 expression and activity R-HSA-8941858
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Neutrophil degranulation R-HSA-6798695
Interleukin-1 signaling R-HSA-9020702
Vif-mediated degradation of APOBEC3G R-HSA-180585
Disorders of transmembrane transporters R-HSA-5619115
Switching of origins to a post-replicative state R-HSA-69052
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Immune System R-HSA-168256
HIV Infection R-HSA-162906
Cellular response to chemical stress R-HSA-9711123
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX3 R-HSA-8878159
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hh mutants are degraded by ERAD R-HSA-5362768
MAPK1/MAPK3 signaling R-HSA-5684996
Intracellular signaling by second messengers R-HSA-9006925
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Antigen processing-Cross presentation R-HSA-1236975
RAF/MAP kinase cascade R-HSA-5673001
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Gene expression (Transcription) R-HSA-74160
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by Hedgehog R-HSA-5358351
Post-translational protein modification R-HSA-597592
Mitotic Metaphase and Anaphase R-HSA-2555396
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Defective CFTR causes cystic fibrosis R-HSA-5678895
S Phase R-HSA-69242
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Orc1 removal from chromatin R-HSA-68949
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 family signaling R-HSA-446652
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
C-type lectin receptors (CLRs) R-HSA-5621481
Stabilization of p53 R-HSA-69541
Cytokine Signaling in Immune system R-HSA-1280215
Programmed Cell Death R-HSA-5357801
FCERI mediated NF-kB activation R-HSA-2871837
Vpu mediated degradation of CD4 R-HSA-180534
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017

Expression Atlas ENSG00000143106
NCBI gene (formerly Entrezgene) 5686
GeneCards 9534
HGNC Symbol HGNC:9534
MIM gene 176844
UniProtKB Gene Name P28066
WikiGene 5686
Gene: PSMB1
Ensembl ID : ENSG00000008018
Description: proteasome 20S subunit beta 1
Gene Synonyms: HC5,PMSB1
6 APIs:
217 Possible Orthologues:

Metabolism R-HSA-1430728
Signaling by WNT R-HSA-195721
Signal Transduction R-HSA-162582
G1/S DNA Damage Checkpoints R-HSA-69615
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Innate Immune System R-HSA-168249
Developmental Biology R-HSA-1266738
Disorders of transmembrane transporters R-HSA-5619115
Ub-specific processing proteases R-HSA-5689880
Signaling by WNT R-HSA-195721
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hedgehog ligand biogenesis R-HSA-5358346
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by NOTCH R-HSA-157118
RNA Polymerase II Transcription R-HSA-73857
Synthesis of DNA R-HSA-69239
G1/S Transition R-HSA-69206
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of RAS by GAPs R-HSA-5658442
Transport of small molecules R-HSA-382551
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of proteins R-HSA-392499
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of RNA R-HSA-8953854
Separation of Sister Chromatids R-HSA-2467813
Hedgehog 'off' state R-HSA-5610787
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Hh mutants are degraded by ERAD R-HSA-5362768
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Transcriptional regulation by RUNX1 R-HSA-8878171
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by Interleukins R-HSA-449147
Deubiquitination R-HSA-5688426
p53-Independent DNA Damage Response R-HSA-69610
Cellular responses to stress R-HSA-2262752
Cyclin E associated events during G1/S transition R-HSA-69202
ABC-family proteins mediated transport R-HSA-382556
G2/M Checkpoints R-HSA-69481
Hedgehog 'on' state R-HSA-5632684
DNA Replication Pre-Initiation R-HSA-69002
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism of amino acids and derivatives R-HSA-71291
Immune System R-HSA-168256
Cellular response to chemical stress R-HSA-9711123
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Disease R-HSA-1643685
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of beta-catenin by the destruction complex R-HSA-195253
Adaptive Immune System R-HSA-1280218
Degradation of DVL R-HSA-4641258
Intracellular signaling by second messengers R-HSA-9006925
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
PTEN Regulation R-HSA-6807070
Infectious disease R-HSA-5663205
Neutrophil degranulation R-HSA-6798695
M Phase R-HSA-68886
Degradation of AXIN R-HSA-4641257
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of RUNX2 expression and activity R-HSA-8939902
Programmed Cell Death R-HSA-5357801
Degradation of GLI2 by the proteasome R-HSA-5610783
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of PTEN stability and activity R-HSA-8948751
Defective CFTR causes cystic fibrosis R-HSA-5678895
CLEC7A (Dectin-1) signaling R-HSA-5607764
Post-translational protein modification R-HSA-597592
S Phase R-HSA-69242
Mitotic G2-G2/M phases R-HSA-453274
Interleukin-1 signaling R-HSA-9020702
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of GLI1 by the proteasome R-HSA-5610780
Signal Transduction R-HSA-162582
Metabolism of polyamines R-HSA-351202
Vif-mediated degradation of APOBEC3G R-HSA-180585
RAF/MAP kinase cascade R-HSA-5673001
Generic Transcription Pathway R-HSA-212436
UCH proteinases R-HSA-5689603
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
C-type lectin receptors (CLRs) R-HSA-5621481
Mitotic Anaphase R-HSA-68882
Cytokine Signaling in Immune system R-HSA-1280215
PIP3 activates AKT signaling R-HSA-1257604
Cell Cycle Checkpoints R-HSA-69620
Metabolism R-HSA-1430728
ABC transporter disorders R-HSA-5619084
Signaling by ROBO receptors R-HSA-376176
KEAP1-NFE2L2 pathway R-HSA-9755511
FCERI mediated NF-kB activation R-HSA-2871837
PCP/CE pathway R-HSA-4086400
Downstream TCR signaling R-HSA-202424
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Axon guidance R-HSA-422475
Regulation of Apoptosis R-HSA-169911
MAPK family signaling cascades R-HSA-5683057
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by NOTCH4 R-HSA-9013694
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCF dependent signaling in response to WNT R-HSA-201681
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Apoptosis R-HSA-109581
Cell Cycle R-HSA-1640170
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Orc1 removal from chromatin R-HSA-68949
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Mitotic Metaphase and Anaphase R-HSA-2555396
NIK-->noncanonical NF-kB signaling R-HSA-5676590
ER-Phagosome pathway R-HSA-1236974
Interleukin-1 family signaling R-HSA-446652
G2/M Transition R-HSA-69275
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cell Cycle, Mitotic R-HSA-69278
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Switching of origins to a post-replicative state R-HSA-69052
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of mitotic cell cycle R-HSA-453276
Regulation of expression of SLITs and ROBOs R-HSA-9010553
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TCR signaling R-HSA-202403
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
DNA Replication R-HSA-69306
Antigen processing-Cross presentation R-HSA-1236975
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stimuli R-HSA-8953897
Stabilization of p53 R-HSA-69541
Signaling by Hedgehog R-HSA-5358351
Vpu mediated degradation of CD4 R-HSA-180534
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Host Interactions of HIV factors R-HSA-162909
MAPK1/MAPK3 signaling R-HSA-5684996
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Transcriptional regulation by RUNX2 R-HSA-8878166
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular response to hypoxia R-HSA-1234174
Neddylation R-HSA-8951664
Regulation of mitotic cell cycle R-HSA-453276
ABC transporter disorders R-HSA-5619084
Metabolism of amino acids and derivatives R-HSA-71291
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog 'on' state R-HSA-5632684
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism of RNA R-HSA-8953854
M Phase R-HSA-68886
Regulation of expression of SLITs and ROBOs R-HSA-9010553
UCH proteinases R-HSA-5689603
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Intracellular signaling by second messengers R-HSA-9006925
Innate Immune System R-HSA-168249
Degradation of DVL R-HSA-4641258
HIV Infection R-HSA-162906
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Separation of Sister Chromatids R-HSA-2467813
Interleukin-1 family signaling R-HSA-446652
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Adaptive Immune System R-HSA-1280218
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic Anaphase R-HSA-68882
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Interleukin-1 signaling R-HSA-9020702
Activation of NF-kappaB in B cells R-HSA-1169091
Deubiquitination R-HSA-5688426
Developmental Biology R-HSA-1266738
Cyclin E associated events during G1/S transition R-HSA-69202
Neutrophil degranulation R-HSA-6798695
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of proteins R-HSA-392499
Defective CFTR causes cystic fibrosis R-HSA-5678895
ABC-family proteins mediated transport R-HSA-382556
Host Interactions of HIV factors R-HSA-162909
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Negative regulation of NOTCH4 signaling R-HSA-9604323
G2/M Checkpoints R-HSA-69481
Regulation of RUNX2 expression and activity R-HSA-8939902
RNA Polymerase II Transcription R-HSA-73857
Signaling by ROBO receptors R-HSA-376176
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle Checkpoints R-HSA-69620
Degradation of AXIN R-HSA-4641257
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by NOTCH4 R-HSA-9013694
Cellular responses to stimuli R-HSA-8953897
Cell Cycle, Mitotic R-HSA-69278
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Post-translational protein modification R-HSA-597592
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Neddylation R-HSA-8951664
PTEN Regulation R-HSA-6807070
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Apoptosis R-HSA-109581
Hedgehog 'off' state R-HSA-5610787
MAPK family signaling cascades R-HSA-5683057
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Assembly of the pre-replicative complex R-HSA-68867
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Vif-mediated degradation of APOBEC3G R-HSA-180585
FCERI mediated NF-kB activation R-HSA-2871837
Downstream TCR signaling R-HSA-202424
Switching of origins to a post-replicative state R-HSA-69052
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic Metaphase and Anaphase R-HSA-2555396
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism R-HSA-1430728
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by NOTCH R-HSA-157118
G1/S DNA Damage Checkpoints R-HSA-69615
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
S Phase R-HSA-69242
RAF/MAP kinase cascade R-HSA-5673001
C-type lectin receptors (CLRs) R-HSA-5621481
Gene expression (Transcription) R-HSA-74160
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Orc1 removal from chromatin R-HSA-68949
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Beta-catenin independent WNT signaling R-HSA-3858494
PCP/CE pathway R-HSA-4086400
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Infectious disease R-HSA-5663205
Vpu mediated degradation of CD4 R-HSA-180534
DNA Replication Pre-Initiation R-HSA-69002
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Ub-specific processing proteases R-HSA-5689880
Transcriptional regulation by RUNX3 R-HSA-8878159
Programmed Cell Death R-HSA-5357801
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX1 R-HSA-8878171
Hh mutants abrogate ligand secretion R-HSA-5387390
Signaling by WNT R-HSA-195721
Signaling by Interleukins R-HSA-449147
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular response to chemical stress R-HSA-9711123
TCR signaling R-HSA-202403
G2/M Transition R-HSA-69275
Disease R-HSA-1643685
Immune System R-HSA-168256
Metabolism of polyamines R-HSA-351202
Cellular responses to stress R-HSA-2262752
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic G2-G2/M phases R-HSA-453274
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
PIP3 activates AKT signaling R-HSA-1257604
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Transport of small molecules R-HSA-382551
DNA Replication R-HSA-69306
Signal Transduction R-HSA-162582
Cellular response to hypoxia R-HSA-1234174
Regulation of PTEN stability and activity R-HSA-8948751
Antigen processing-Cross presentation R-HSA-1236975
p53-Independent DNA Damage Response R-HSA-69610
ER-Phagosome pathway R-HSA-1236974
G1/S Transition R-HSA-69206
Cell Cycle R-HSA-1640170
TCF dependent signaling in response to WNT R-HSA-201681
Disorders of transmembrane transporters R-HSA-5619115
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Generic Transcription Pathway R-HSA-212436
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of beta-catenin by the destruction complex R-HSA-195253
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Axon guidance R-HSA-422475
Regulation of Apoptosis R-HSA-169911
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Stabilization of p53 R-HSA-69541
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by Hedgehog R-HSA-5358351
Regulation of RAS by GAPs R-HSA-5658442
Class I MHC mediated antigen processing & presentation R-HSA-983169
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Beta-catenin independent WNT signaling R-HSA-3858494
Neddylation R-HSA-8951664
Downstream TCR signaling R-HSA-202424
Neutrophil degranulation R-HSA-6798695
Intracellular signaling by second messengers R-HSA-9006925
ER-Phagosome pathway R-HSA-1236974
Transcriptional regulation by RUNX2 R-HSA-8878166
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of RUNX3 expression and activity R-HSA-8941858
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX1 R-HSA-8878171
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Dependent G1 DNA Damage Response R-HSA-69563
DNA Replication Pre-Initiation R-HSA-69002
Hedgehog 'on' state R-HSA-5632684
Metabolism of polyamines R-HSA-351202
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Class I MHC mediated antigen processing & presentation R-HSA-983169
Disease R-HSA-1643685
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transport of small molecules R-HSA-382551
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by Hedgehog R-HSA-5358351
TCF dependent signaling in response to WNT R-HSA-201681
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Programmed Cell Death R-HSA-5357801
M Phase R-HSA-68886
Hedgehog 'off' state R-HSA-5610787
Adaptive Immune System R-HSA-1280218
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ABC-family proteins mediated transport R-HSA-382556
Antigen processing-Cross presentation R-HSA-1236975
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
G2/M Transition R-HSA-69275
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cell Cycle Checkpoints R-HSA-69620
Orc1 removal from chromatin R-HSA-68949
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Switching of origins to a post-replicative state R-HSA-69052
Degradation of beta-catenin by the destruction complex R-HSA-195253
FCERI mediated NF-kB activation R-HSA-2871837
Infectious disease R-HSA-5663205
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cell Cycle, Mitotic R-HSA-69278
Hh mutants abrogate ligand secretion R-HSA-5387390
Signaling by ROBO receptors R-HSA-376176
Transcriptional regulation by RUNX3 R-HSA-8878159
TCR signaling R-HSA-202403
KEAP1-NFE2L2 pathway R-HSA-9755511
Interleukin-1 signaling R-HSA-9020702
Mitotic G2-G2/M phases R-HSA-453274
Nuclear events mediated by NFE2L2 R-HSA-9759194
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of GLI1 by the proteasome R-HSA-5610780
Separation of Sister Chromatids R-HSA-2467813
Signaling by Interleukins R-HSA-449147
Regulation of Apoptosis R-HSA-169911
HIV Infection R-HSA-162906
DNA Replication R-HSA-69306
Metabolism of amino acids and derivatives R-HSA-71291
Innate Immune System R-HSA-168249
PCP/CE pathway R-HSA-4086400
C-type lectin receptors (CLRs) R-HSA-5621481
Metabolism R-HSA-1430728
Cellular responses to stimuli R-HSA-8953897
Metabolism of RNA R-HSA-8953854
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Mitotic Anaphase R-HSA-68882
Signaling by NOTCH4 R-HSA-9013694
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle R-HSA-1640170
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hh mutants are degraded by ERAD R-HSA-5362768
S Phase R-HSA-69242
Cyclin E associated events during G1/S transition R-HSA-69202
Cytokine Signaling in Immune system R-HSA-1280215
G1/S Transition R-HSA-69206
Disorders of transmembrane transporters R-HSA-5619115
MAPK6/MAPK4 signaling R-HSA-5687128
Synthesis of DNA R-HSA-69239
Immune System R-HSA-168256
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Interleukin-1 family signaling R-HSA-446652
Assembly of the pre-replicative complex R-HSA-68867
Signaling by NOTCH R-HSA-157118
Regulation of RAS by GAPs R-HSA-5658442
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Checkpoints R-HSA-69481
Degradation of AXIN R-HSA-4641257
RAF/MAP kinase cascade R-HSA-5673001
Asymmetric localization of PCP proteins R-HSA-4608870
Apoptosis R-HSA-109581
Host Interactions of HIV factors R-HSA-162909
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RNA Polymerase II Transcription R-HSA-73857
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by the B Cell Receptor (BCR) R-HSA-983705
ABC transporter disorders R-HSA-5619084
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cellular response to hypoxia R-HSA-1234174
Signal Transduction R-HSA-162582
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
PIP3 activates AKT signaling R-HSA-1257604
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK family signaling cascades R-HSA-5683057
Signaling by WNT R-HSA-195721
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism of proteins R-HSA-392499
UCH proteinases R-HSA-5689603
Activation of NF-kappaB in B cells R-HSA-1169091
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Ub-specific processing proteases R-HSA-5689880
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Developmental Biology R-HSA-1266738
Generic Transcription Pathway R-HSA-212436
Degradation of DVL R-HSA-4641258
PTEN Regulation R-HSA-6807070
Cellular response to chemical stress R-HSA-9711123
Regulation of PTEN stability and activity R-HSA-8948751
Cellular responses to stress R-HSA-2262752
Degradation of GLI2 by the proteasome R-HSA-5610783
Axon guidance R-HSA-422475
Deubiquitination R-HSA-5688426
Nervous system development R-HSA-9675108
p53-Independent DNA Damage Response R-HSA-69610
Stabilization of p53 R-HSA-69541
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of mitotic cell cycle R-HSA-453276
Vif-mediated degradation of APOBEC3G R-HSA-180585
G1/S DNA Damage Checkpoints R-HSA-69615
Mitotic G1 phase and G1/S transition R-HSA-453279
Disease R-HSA-1643685
FCERI mediated NF-kB activation R-HSA-2871837
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
TCR signaling R-HSA-202403
Downstream TCR signaling R-HSA-202424
Regulation of PTEN stability and activity R-HSA-8948751
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Beta-catenin independent WNT signaling R-HSA-3858494
Transcriptional regulation by RUNX1 R-HSA-8878171
CLEC7A (Dectin-1) signaling R-HSA-5607764
Switching of origins to a post-replicative state R-HSA-69052
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
RNA Polymerase II Transcription R-HSA-73857
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cellular response to hypoxia R-HSA-1234174
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Transcriptional regulation by RUNX2 R-HSA-8878166
Transcriptional regulation by RUNX3 R-HSA-8878159
Mitotic G1 phase and G1/S transition R-HSA-453279
Separation of Sister Chromatids R-HSA-2467813
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of beta-catenin by the destruction complex R-HSA-195253
Mitotic G2-G2/M phases R-HSA-453274
Nervous system development R-HSA-9675108
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Hh mutants abrogate ligand secretion R-HSA-5387390
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK6/MAPK4 signaling R-HSA-5687128
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic Metaphase and Anaphase R-HSA-2555396
Cytokine Signaling in Immune system R-HSA-1280215
G1/S DNA Damage Checkpoints R-HSA-69615
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
C-type lectin receptors (CLRs) R-HSA-5621481
DNA Replication Pre-Initiation R-HSA-69002
Regulation of mitotic cell cycle R-HSA-453276
MAPK1/MAPK3 signaling R-HSA-5684996
Apoptosis R-HSA-109581
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of RAS by GAPs R-HSA-5658442
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
M Phase R-HSA-68886
G2/M Checkpoints R-HSA-69481
G1/S Transition R-HSA-69206
Regulation of RUNX3 expression and activity R-HSA-8941858
PCP/CE pathway R-HSA-4086400
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog ligand biogenesis R-HSA-5358346
TCF dependent signaling in response to WNT R-HSA-201681
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular response to chemical stress R-HSA-9711123
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic Anaphase R-HSA-68882
Interleukin-1 family signaling R-HSA-446652
S Phase R-HSA-69242
Metabolism of RNA R-HSA-8953854
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of Apoptosis R-HSA-169911
PIP3 activates AKT signaling R-HSA-1257604
Defective CFTR causes cystic fibrosis R-HSA-5678895
UCH proteinases R-HSA-5689603
Signaling by NOTCH4 R-HSA-9013694
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
HIV Infection R-HSA-162906
Deubiquitination R-HSA-5688426
Degradation of GLI2 by the proteasome R-HSA-5610783
G2/M Transition R-HSA-69275
Programmed Cell Death R-HSA-5357801
Orc1 removal from chromatin R-HSA-68949
Stabilization of p53 R-HSA-69541
Metabolism of polyamines R-HSA-351202
Cell Cycle Checkpoints R-HSA-69620
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Hedgehog 'off' state R-HSA-5610787
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Post-translational protein modification R-HSA-597592
PTEN Regulation R-HSA-6807070
ER-Phagosome pathway R-HSA-1236974
Adaptive Immune System R-HSA-1280218
RAF/MAP kinase cascade R-HSA-5673001
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
DNA Replication R-HSA-69306
Synthesis of DNA R-HSA-69239
Interleukin-1 signaling R-HSA-9020702
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of DVL R-HSA-4641258
Class I MHC mediated antigen processing & presentation R-HSA-983169
Signaling by Hedgehog R-HSA-5358351
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Immune System R-HSA-168256
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular responses to stimuli R-HSA-8953897
Cyclin E associated events during G1/S transition R-HSA-69202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of RUNX2 expression and activity R-HSA-8939902
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Disorders of transmembrane transporters R-HSA-5619115
Generic Transcription Pathway R-HSA-212436
Assembly of the pre-replicative complex R-HSA-68867
Cell Cycle R-HSA-1640170
Innate Immune System R-HSA-168249
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Host Interactions of HIV factors R-HSA-162909
ABC transporter disorders R-HSA-5619084
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transport of small molecules R-HSA-382551
Vpu mediated degradation of CD4 R-HSA-180534
Cell Cycle, Mitotic R-HSA-69278
Metabolism R-HSA-1430728
Hedgehog 'on' state R-HSA-5632684
ABC-family proteins mediated transport R-HSA-382556
Antigen processing-Cross presentation R-HSA-1236975
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
MAPK family signaling cascades R-HSA-5683057
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Independent DNA Damage Response R-HSA-69610
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Axon guidance R-HSA-422475
Neutrophil degranulation R-HSA-6798695
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Gene expression (Transcription) R-HSA-74160
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by ROBO receptors R-HSA-376176
Degradation of AXIN R-HSA-4641257
Signaling by NOTCH R-HSA-157118
Signal Transduction R-HSA-162582
Infectious disease R-HSA-5663205
Signaling by WNT R-HSA-195721
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Neddylation R-HSA-8951664
Signaling by Interleukins R-HSA-449147
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
C-type lectin receptors (CLRs) R-HSA-5621481
Apoptosis R-HSA-109581
Signaling by WNT R-HSA-195721
Signaling by Hedgehog R-HSA-5358351
Interleukin-1 signaling R-HSA-9020702
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of DVL R-HSA-4641258
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Intracellular signaling by second messengers R-HSA-9006925
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transport of small molecules R-HSA-382551
Mitotic G1 phase and G1/S transition R-HSA-453279
Programmed Cell Death R-HSA-5357801
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Assembly of the pre-replicative complex R-HSA-68867
p53-Dependent G1 DNA Damage Response R-HSA-69563
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
PCP/CE pathway R-HSA-4086400
Nervous system development R-HSA-9675108
Regulation of RUNX3 expression and activity R-HSA-8941858
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of beta-catenin by the destruction complex R-HSA-195253
Separation of Sister Chromatids R-HSA-2467813
Cellular responses to stimuli R-HSA-8953897
Downstream TCR signaling R-HSA-202424
Signaling by Interleukins R-HSA-449147
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cytokine Signaling in Immune system R-HSA-1280215
Cell Cycle Checkpoints R-HSA-69620
HIV Infection R-HSA-162906
Mitotic G2-G2/M phases R-HSA-453274
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
DNA Replication R-HSA-69306
Mitotic Anaphase R-HSA-68882
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stress R-HSA-2262752
Deubiquitination R-HSA-5688426
Signaling by ROBO receptors R-HSA-376176
Adaptive Immune System R-HSA-1280218
Metabolism of RNA R-HSA-8953854
Nuclear events mediated by NFE2L2 R-HSA-9759194
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of polyamines R-HSA-351202
Regulation of RAS by GAPs R-HSA-5658442
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH4 R-HSA-9013694
Regulation of RUNX2 expression and activity R-HSA-8939902
ER-Phagosome pathway R-HSA-1236974
TCR signaling R-HSA-202403
Antigen processing-Cross presentation R-HSA-1236975
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
FCERI mediated NF-kB activation R-HSA-2871837
Disorders of transmembrane transporters R-HSA-5619115
MAPK6/MAPK4 signaling R-HSA-5687128
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
G1/S Transition R-HSA-69206
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
Regulation of mitotic cell cycle R-HSA-453276
Axon guidance R-HSA-422475
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle R-HSA-1640170
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Disease R-HSA-1643685
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Developmental Biology R-HSA-1266738
Degradation of GLI2 by the proteasome R-HSA-5610783
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
G2/M Transition R-HSA-69275
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX1 R-HSA-8878171
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by NOTCH R-HSA-157118
Host Interactions of HIV factors R-HSA-162909
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX3 R-HSA-8878159
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Orc1 removal from chromatin R-HSA-68949
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Metabolism of amino acids and derivatives R-HSA-71291
Post-translational protein modification R-HSA-597592
Vpu mediated degradation of CD4 R-HSA-180534
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
S Phase R-HSA-69242
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of Apoptosis R-HSA-169911
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK family signaling cascades R-HSA-5683057
Regulation of PTEN stability and activity R-HSA-8948751
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of GLI1 by the proteasome R-HSA-5610780
Hedgehog 'off' state R-HSA-5610787
UCH proteinases R-HSA-5689603
KEAP1-NFE2L2 pathway R-HSA-9755511
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hh mutants abrogate ligand secretion R-HSA-5387390
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of proteins R-HSA-392499
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cyclin E associated events during G1/S transition R-HSA-69202
Defective CFTR causes cystic fibrosis R-HSA-5678895
MAPK1/MAPK3 signaling R-HSA-5684996
Beta-catenin independent WNT signaling R-HSA-3858494
Ub-specific processing proteases R-HSA-5689880
Signal Transduction R-HSA-162582
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular response to hypoxia R-HSA-1234174
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Neutrophil degranulation R-HSA-6798695
RAF/MAP kinase cascade R-HSA-5673001
Hh mutants are degraded by ERAD R-HSA-5362768
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
TCF dependent signaling in response to WNT R-HSA-201681
Infectious disease R-HSA-5663205
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of AXIN R-HSA-4641257
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
DNA Replication Pre-Initiation R-HSA-69002
M Phase R-HSA-68886
Asymmetric localization of PCP proteins R-HSA-4608870
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 family signaling R-HSA-446652
Cellular response to chemical stress R-HSA-9711123
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PTEN Regulation R-HSA-6807070
RNA Polymerase II Transcription R-HSA-73857
ABC-family proteins mediated transport R-HSA-382556
Stabilization of p53 R-HSA-69541
Neddylation R-HSA-8951664
Activation of NF-kappaB in B cells R-HSA-1169091
G2/M Checkpoints R-HSA-69481
p53-Independent DNA Damage Response R-HSA-69610
Nervous system development R-HSA-9675108
Ub-specific processing proteases R-HSA-5689880
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Neddylation R-HSA-8951664
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1 DNA Damage Response R-HSA-69563
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Stabilization of p53 R-HSA-69541
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by WNT R-HSA-195721
Hh mutants abrogate ligand secretion R-HSA-5387390
Transcriptional regulation by RUNX3 R-HSA-8878159
Metabolism of proteins R-HSA-392499
Disorders of transmembrane transporters R-HSA-5619115
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Host Interactions of HIV factors R-HSA-162909
Cell Cycle R-HSA-1640170
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of DVL R-HSA-4641258
Class I MHC mediated antigen processing & presentation R-HSA-983169
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of AXIN R-HSA-4641257
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of GLI2 by the proteasome R-HSA-5610783
Assembly of the pre-replicative complex R-HSA-68867
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of expression of SLITs and ROBOs R-HSA-9010553
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vpu mediated degradation of CD4 R-HSA-180534
Metabolism R-HSA-1430728
Mitotic Metaphase and Anaphase R-HSA-2555396
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Separation of Sister Chromatids R-HSA-2467813
Metabolism of amino acids and derivatives R-HSA-71291
DNA Replication Pre-Initiation R-HSA-69002
G2/M Checkpoints R-HSA-69481
ABC transporter disorders R-HSA-5619084
Hedgehog 'on' state R-HSA-5632684
RNA Polymerase II Transcription R-HSA-73857
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by NOTCH4 R-HSA-9013694
Hh mutants are degraded by ERAD R-HSA-5362768
TCR signaling R-HSA-202403
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Gene expression (Transcription) R-HSA-74160
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Apoptosis R-HSA-109581
Innate Immune System R-HSA-168249
Cell Cycle, Mitotic R-HSA-69278
G2/M Transition R-HSA-69275
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Downstream TCR signaling R-HSA-202424
Synthesis of DNA R-HSA-69239
Signaling by ROBO receptors R-HSA-376176
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
p53-Independent DNA Damage Response R-HSA-69610
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Negative regulation of NOTCH4 signaling R-HSA-9604323
Deubiquitination R-HSA-5688426
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Nuclear events mediated by NFE2L2 R-HSA-9759194
Adaptive Immune System R-HSA-1280218
Developmental Biology R-HSA-1266738
Interleukin-1 signaling R-HSA-9020702
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of RUNX2 expression and activity R-HSA-8939902
HIV Infection R-HSA-162906
FCERI mediated NF-kB activation R-HSA-2871837
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
G1/S DNA Damage Checkpoints R-HSA-69615
Interleukin-1 family signaling R-HSA-446652
PTEN Regulation R-HSA-6807070
Regulation of mitotic cell cycle R-HSA-453276
Cellular responses to stimuli R-HSA-8953897
Intracellular signaling by second messengers R-HSA-9006925
RAF/MAP kinase cascade R-HSA-5673001
Signaling by NOTCH R-HSA-157118
Mitotic G2-G2/M phases R-HSA-453274
Switching of origins to a post-replicative state R-HSA-69052
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Infectious disease R-HSA-5663205
C-type lectin receptors (CLRs) R-HSA-5621481
Activation of NF-kappaB in B cells R-HSA-1169091
Disease R-HSA-1643685
Degradation of GLI1 by the proteasome R-HSA-5610780
G1/S Transition R-HSA-69206
Signaling by Hedgehog R-HSA-5358351
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Generic Transcription Pathway R-HSA-212436
Post-translational protein modification R-HSA-597592
Neutrophil degranulation R-HSA-6798695
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
M Phase R-HSA-68886
Cellular response to hypoxia R-HSA-1234174
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Mitotic Anaphase R-HSA-68882
MAPK family signaling cascades R-HSA-5683057
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cell Cycle Checkpoints R-HSA-69620
Regulation of RAS by GAPs R-HSA-5658442
ER-Phagosome pathway R-HSA-1236974
Signaling by Interleukins R-HSA-449147
UCH proteinases R-HSA-5689603
Orc1 removal from chromatin R-HSA-68949
Transport of small molecules R-HSA-382551
Regulation of RUNX3 expression and activity R-HSA-8941858
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of RNA R-HSA-8953854
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of Apoptosis R-HSA-169911
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Antigen processing-Cross presentation R-HSA-1236975
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stress R-HSA-2262752
Metabolism of polyamines R-HSA-351202
Cellular response to chemical stress R-HSA-9711123
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX2 R-HSA-8878166
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
S Phase R-HSA-69242
MAPK1/MAPK3 signaling R-HSA-5684996
Immune System R-HSA-168256
PCP/CE pathway R-HSA-4086400
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
ABC-family proteins mediated transport R-HSA-382556
Programmed Cell Death R-HSA-5357801
CLEC7A (Dectin-1) signaling R-HSA-5607764
DNA Replication R-HSA-69306
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signal Transduction R-HSA-162582
Cytokine Signaling in Immune system R-HSA-1280215
Axon guidance R-HSA-422475
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Asymmetric localization of PCP proteins R-HSA-4608870
TCF dependent signaling in response to WNT R-HSA-201681
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Orc1 removal from chromatin R-HSA-68949
ER-Phagosome pathway R-HSA-1236974
Cellular response to chemical stress R-HSA-9711123
Class I MHC mediated antigen processing & presentation R-HSA-983169
MAPK family signaling cascades R-HSA-5683057
Nuclear events mediated by NFE2L2 R-HSA-9759194
G2/M Transition R-HSA-69275
Cell Cycle R-HSA-1640170
Assembly of the pre-replicative complex R-HSA-68867
Vif-mediated degradation of APOBEC3G R-HSA-180585
Interleukin-1 signaling R-HSA-9020702
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of GLI1 by the proteasome R-HSA-5610780
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cytokine Signaling in Immune system R-HSA-1280215
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transport of small molecules R-HSA-382551
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Switching of origins to a post-replicative state R-HSA-69052
S Phase R-HSA-69242
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH4 R-HSA-9013694
Gene expression (Transcription) R-HSA-74160
Host Interactions of HIV factors R-HSA-162909
PTEN Regulation R-HSA-6807070
ABC transporter disorders R-HSA-5619084
Hedgehog ligand biogenesis R-HSA-5358346
PCP/CE pathway R-HSA-4086400
M Phase R-HSA-68886
Regulation of Apoptosis R-HSA-169911
Regulation of RUNX2 expression and activity R-HSA-8939902
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle Checkpoints R-HSA-69620
Antigen processing-Cross presentation R-HSA-1236975
Stabilization of p53 R-HSA-69541
UCH proteinases R-HSA-5689603
Mitotic Metaphase and Anaphase R-HSA-2555396
HIV Infection R-HSA-162906
G1/S Transition R-HSA-69206
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of RNA R-HSA-8953854
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Hh mutants abrogate ligand secretion R-HSA-5387390
Transcriptional regulation by RUNX2 R-HSA-8878166
TCR signaling R-HSA-202403
C-type lectin receptors (CLRs) R-HSA-5621481
TCF dependent signaling in response to WNT R-HSA-201681
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular responses to stress R-HSA-2262752
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of AXIN R-HSA-4641257
Neddylation R-HSA-8951664
Nervous system development R-HSA-9675108
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RAF/MAP kinase cascade R-HSA-5673001
DNA Replication R-HSA-69306
Defective CFTR causes cystic fibrosis R-HSA-5678895
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Immune System R-HSA-168256
Degradation of beta-catenin by the destruction complex R-HSA-195253
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Mitotic Anaphase R-HSA-68882
Regulation of RUNX3 expression and activity R-HSA-8941858
Post-translational protein modification R-HSA-597592
Neutrophil degranulation R-HSA-6798695
Vpu mediated degradation of CD4 R-HSA-180534
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
G2/M Checkpoints R-HSA-69481
Signaling by NOTCH R-HSA-157118
Degradation of DVL R-HSA-4641258
Innate Immune System R-HSA-168249
Deubiquitination R-HSA-5688426
Synthesis of DNA R-HSA-69239
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Developmental Biology R-HSA-1266738
Downstream TCR signaling R-HSA-202424
Apoptosis R-HSA-109581
Cellular response to hypoxia R-HSA-1234174
Infectious disease R-HSA-5663205
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of proteins R-HSA-392499
Regulation of mitotic cell cycle R-HSA-453276
Signaling by Interleukins R-HSA-449147
Cyclin E associated events during G1/S transition R-HSA-69202
Interleukin-1 family signaling R-HSA-446652
Hh mutants are degraded by ERAD R-HSA-5362768
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Programmed Cell Death R-HSA-5357801
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Separation of Sister Chromatids R-HSA-2467813
Axon guidance R-HSA-422475
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
KEAP1-NFE2L2 pathway R-HSA-9755511
MAPK6/MAPK4 signaling R-HSA-5687128
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Transcriptional regulation by RUNX1 R-HSA-8878171
Disorders of transmembrane transporters R-HSA-5619115
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transcriptional regulation by RUNX3 R-HSA-8878159
Intracellular signaling by second messengers R-HSA-9006925
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signal Transduction R-HSA-162582
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Mitotic G1 phase and G1/S transition R-HSA-453279
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Hedgehog 'on' state R-HSA-5632684
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Mitotic G2-G2/M phases R-HSA-453274
ABC-family proteins mediated transport R-HSA-382556
Metabolism of amino acids and derivatives R-HSA-71291
FCERI mediated NF-kB activation R-HSA-2871837
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hedgehog 'off' state R-HSA-5610787
PIP3 activates AKT signaling R-HSA-1257604
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of RAS by GAPs R-HSA-5658442
Generic Transcription Pathway R-HSA-212436
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Hedgehog R-HSA-5358351
Ub-specific processing proteases R-HSA-5689880
Beta-catenin independent WNT signaling R-HSA-3858494
Activation of NF-kappaB in B cells R-HSA-1169091
RNA Polymerase II Transcription R-HSA-73857
Signaling by ROBO receptors R-HSA-376176
Adaptive Immune System R-HSA-1280218
Cellular responses to stimuli R-HSA-8953897
Metabolism of polyamines R-HSA-351202
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism R-HSA-1430728
Cell Cycle, Mitotic R-HSA-69278
Synthesis of DNA R-HSA-69239
ABC-family proteins mediated transport R-HSA-382556
Antigen processing-Cross presentation R-HSA-1236975
Generic Transcription Pathway R-HSA-212436
Beta-catenin independent WNT signaling R-HSA-3858494
Transcriptional regulation by RUNX3 R-HSA-8878159
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
Metabolism of amino acids and derivatives R-HSA-71291
Cell Cycle R-HSA-1640170
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Downstream TCR signaling R-HSA-202424
Neutrophil degranulation R-HSA-6798695
Disorders of transmembrane transporters R-HSA-5619115
Hedgehog 'on' state R-HSA-5632684
Degradation of AXIN R-HSA-4641257
Adaptive Immune System R-HSA-1280218
Signaling by Interleukins R-HSA-449147
HIV Infection R-HSA-162906
p53-Independent DNA Damage Response R-HSA-69610
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Developmental Biology R-HSA-1266738
FCERI mediated NF-kB activation R-HSA-2871837
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Interleukin-1 family signaling R-HSA-446652
RAF/MAP kinase cascade R-HSA-5673001
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular response to chemical stress R-HSA-9711123
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular responses to stimuli R-HSA-8953897
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of Apoptosis R-HSA-169911
TCR signaling R-HSA-202403
Metabolism R-HSA-1430728
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Post-translational protein modification R-HSA-597592
Switching of origins to a post-replicative state R-HSA-69052
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Asymmetric localization of PCP proteins R-HSA-4608870
Cell Cycle Checkpoints R-HSA-69620
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Class I MHC mediated antigen processing & presentation R-HSA-983169
DNA Replication R-HSA-69306
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hh mutants are degraded by ERAD R-HSA-5362768
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Mitotic Metaphase and Anaphase R-HSA-2555396
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of mitotic cell cycle R-HSA-453276
Cellular responses to stress R-HSA-2262752
Assembly of the pre-replicative complex R-HSA-68867
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by ROBO receptors R-HSA-376176
Intracellular signaling by second messengers R-HSA-9006925
UCH proteinases R-HSA-5689603
Hh mutants abrogate ligand secretion R-HSA-5387390
ABC transporter disorders R-HSA-5619084
DNA Replication Pre-Initiation R-HSA-69002
Separation of Sister Chromatids R-HSA-2467813
Nuclear events mediated by NFE2L2 R-HSA-9759194
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism of polyamines R-HSA-351202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cyclin E associated events during G1/S transition R-HSA-69202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK1/MAPK3 signaling R-HSA-5684996
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PTEN Regulation R-HSA-6807070
Mitotic G2-G2/M phases R-HSA-453274
Innate Immune System R-HSA-168249
Signaling by WNT R-HSA-195721
G2/M Checkpoints R-HSA-69481
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
Neddylation R-HSA-8951664
TCF dependent signaling in response to WNT R-HSA-201681
ER-Phagosome pathway R-HSA-1236974
Stabilization of p53 R-HSA-69541
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Negative regulation of NOTCH4 signaling R-HSA-9604323
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Mitotic G1 phase and G1/S transition R-HSA-453279
Programmed Cell Death R-HSA-5357801
KEAP1-NFE2L2 pathway R-HSA-9755511
Host Interactions of HIV factors R-HSA-162909
PCP/CE pathway R-HSA-4086400
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vif-mediated degradation of APOBEC3G R-HSA-180585
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of RAS by GAPs R-HSA-5658442
RNA Polymerase II Transcription R-HSA-73857
Deubiquitination R-HSA-5688426
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hedgehog 'off' state R-HSA-5610787
M Phase R-HSA-68886
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Interleukin-1 signaling R-HSA-9020702
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by NOTCH R-HSA-157118
Cell Cycle, Mitotic R-HSA-69278
Signaling by NOTCH4 R-HSA-9013694
Regulation of PTEN stability and activity R-HSA-8948751
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of beta-catenin by the destruction complex R-HSA-195253
Metabolism of proteins R-HSA-392499
PIP3 activates AKT signaling R-HSA-1257604
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular response to hypoxia R-HSA-1234174
Apoptosis R-HSA-109581
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RUNX3 expression and activity R-HSA-8941858
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
G1/S Transition R-HSA-69206
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transport of small molecules R-HSA-382551
Metabolism of RNA R-HSA-8953854
Axon guidance R-HSA-422475
Immune System R-HSA-168256
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI2 by the proteasome R-HSA-5610783
Degradation of DVL R-HSA-4641258
Ub-specific processing proteases R-HSA-5689880
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by Hedgehog R-HSA-5358351
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Gene expression (Transcription) R-HSA-74160
Regulation of RUNX2 expression and activity R-HSA-8939902
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Activation of NF-kappaB in B cells R-HSA-1169091
Orc1 removal from chromatin R-HSA-68949
G2/M Transition R-HSA-69275
Hedgehog ligand biogenesis R-HSA-5358346
Disease R-HSA-1643685
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of RNA R-HSA-8953854
G2/M Transition R-HSA-69275
DNA Replication R-HSA-69306
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Separation of Sister Chromatids R-HSA-2467813
MAPK1/MAPK3 signaling R-HSA-5684996
Beta-catenin independent WNT signaling R-HSA-3858494
Adaptive Immune System R-HSA-1280218
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hedgehog 'on' state R-HSA-5632684
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Transcriptional regulation by RUNX3 R-HSA-8878159
UCH proteinases R-HSA-5689603
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by NOTCH4 R-HSA-9013694
Interleukin-1 signaling R-HSA-9020702
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by ROBO receptors R-HSA-376176
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of RUNX2 expression and activity R-HSA-8939902
Vpu mediated degradation of CD4 R-HSA-180534
Synthesis of DNA R-HSA-69239
Programmed Cell Death R-HSA-5357801
Neddylation R-HSA-8951664
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
MAPK family signaling cascades R-HSA-5683057
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
Mitotic Anaphase R-HSA-68882
C-type lectin receptors (CLRs) R-HSA-5621481
Cyclin E associated events during G1/S transition R-HSA-69202
ABC-family proteins mediated transport R-HSA-382556
Antigen processing-Cross presentation R-HSA-1236975
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
RNA Polymerase II Transcription R-HSA-73857
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Degradation of GLI1 by the proteasome R-HSA-5610780
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Metabolism R-HSA-1430728
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX2 R-HSA-8878166
Axon guidance R-HSA-422475
Host Interactions of HIV factors R-HSA-162909
Infectious disease R-HSA-5663205
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Metabolism of proteins R-HSA-392499
Regulation of RUNX3 expression and activity R-HSA-8941858
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
FCERI mediated NF-kB activation R-HSA-2871837
Hh mutants are degraded by ERAD R-HSA-5362768
TCR signaling R-HSA-202403
Signaling by Interleukins R-HSA-449147
p53-Independent DNA Damage Response R-HSA-69610
Downstream TCR signaling R-HSA-202424
Regulation of PTEN stability and activity R-HSA-8948751
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog ligand biogenesis R-HSA-5358346
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle R-HSA-1640170
Metabolism of amino acids and derivatives R-HSA-71291
Disease R-HSA-1643685
Apoptosis R-HSA-109581
Mitotic G1 phase and G1/S transition R-HSA-453279
HIV Infection R-HSA-162906
Switching of origins to a post-replicative state R-HSA-69052
ER-Phagosome pathway R-HSA-1236974
Disorders of transmembrane transporters R-HSA-5619115
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Innate Immune System R-HSA-168249
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of DVL R-HSA-4641258
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vif-mediated degradation of APOBEC3G R-HSA-180585
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RAF/MAP kinase cascade R-HSA-5673001
Cellular responses to stimuli R-HSA-8953897
p53-Dependent G1 DNA Damage Response R-HSA-69563
Developmental Biology R-HSA-1266738
Cell Cycle Checkpoints R-HSA-69620
G2/M Checkpoints R-HSA-69481
Class I MHC mediated antigen processing & presentation R-HSA-983169
Generic Transcription Pathway R-HSA-212436
DNA Replication Pre-Initiation R-HSA-69002
PCP/CE pathway R-HSA-4086400
Intracellular signaling by second messengers R-HSA-9006925
Degradation of GLI2 by the proteasome R-HSA-5610783
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of beta-catenin by the destruction complex R-HSA-195253
Neutrophil degranulation R-HSA-6798695
Hh mutants abrogate ligand secretion R-HSA-5387390
ABC transporter disorders R-HSA-5619084
Cellular responses to stress R-HSA-2262752
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Stabilization of p53 R-HSA-69541
Metabolism of polyamines R-HSA-351202
Signal Transduction R-HSA-162582
Ub-specific processing proteases R-HSA-5689880
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Orc1 removal from chromatin R-HSA-68949
Immune System R-HSA-168256
Cellular response to hypoxia R-HSA-1234174
Signaling by WNT R-HSA-195721
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PTEN Regulation R-HSA-6807070
Hedgehog 'off' state R-HSA-5610787
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
CLEC7A (Dectin-1) signaling R-HSA-5607764
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of RAS by GAPs R-HSA-5658442
PIP3 activates AKT signaling R-HSA-1257604
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic G2-G2/M phases R-HSA-453274
Regulation of Apoptosis R-HSA-169911
Transport of small molecules R-HSA-382551
Regulation of mitotic cell cycle R-HSA-453276
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by NOTCH R-HSA-157118
G1/S Transition R-HSA-69206
Cell Cycle, Mitotic R-HSA-69278
Regulation of expression of SLITs and ROBOs R-HSA-9010553
M Phase R-HSA-68886
Cellular response to chemical stress R-HSA-9711123
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Activation of NF-kappaB in B cells R-HSA-1169091
Gene expression (Transcription) R-HSA-74160
Interleukin-1 family signaling R-HSA-446652
Assembly of the pre-replicative complex R-HSA-68867
Negative regulation of NOTCH4 signaling R-HSA-9604323
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Post-translational protein modification R-HSA-597592
Degradation of AXIN R-HSA-4641257
Deubiquitination R-HSA-5688426
Nervous system development R-HSA-9675108
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
DNA Replication R-HSA-69306
Host Interactions of HIV factors R-HSA-162909
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transport of small molecules R-HSA-382551
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transcriptional regulation by RUNX2 R-HSA-8878166
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Cytokine Signaling in Immune system R-HSA-1280215
ABC transporter disorders R-HSA-5619084
Signal Transduction R-HSA-162582
C-type lectin receptors (CLRs) R-HSA-5621481
Mitotic Anaphase R-HSA-68882
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by WNT R-HSA-195721
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX3 R-HSA-8878159
G1/S DNA Damage Checkpoints R-HSA-69615
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of PTEN stability and activity R-HSA-8948751
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Developmental Biology R-HSA-1266738
Innate Immune System R-HSA-168249
Stabilization of p53 R-HSA-69541
Negative regulation of NOTCH4 signaling R-HSA-9604323
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Nervous system development R-HSA-9675108
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by NOTCH R-HSA-157118
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular response to hypoxia R-HSA-1234174
PTEN Regulation R-HSA-6807070
UCH proteinases R-HSA-5689603
MAPK family signaling cascades R-HSA-5683057
Cellular response to chemical stress R-HSA-9711123
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCR signaling R-HSA-202403
Synthesis of DNA R-HSA-69239
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Downstream TCR signaling R-HSA-202424
RAF/MAP kinase cascade R-HSA-5673001
Mitotic Metaphase and Anaphase R-HSA-2555396
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Checkpoints R-HSA-69481
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX1 R-HSA-8878171
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Infectious disease R-HSA-5663205
Neutrophil degranulation R-HSA-6798695
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Asymmetric localization of PCP proteins R-HSA-4608870
Class I MHC mediated antigen processing & presentation R-HSA-983169
FCERI mediated NF-kB activation R-HSA-2871837
Programmed Cell Death R-HSA-5357801
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Independent DNA Damage Response R-HSA-69610
M Phase R-HSA-68886
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Apoptosis R-HSA-109581
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle Checkpoints R-HSA-69620
Cellular responses to stress R-HSA-2262752
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Mitotic G2-G2/M phases R-HSA-453274
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism of proteins R-HSA-392499
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of RNA R-HSA-8953854
Cyclin E associated events during G1/S transition R-HSA-69202
Generic Transcription Pathway R-HSA-212436
Intracellular signaling by second messengers R-HSA-9006925
Post-translational protein modification R-HSA-597592
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog 'on' state R-HSA-5632684
HIV Infection R-HSA-162906
G1/S Transition R-HSA-69206
Metabolism of polyamines R-HSA-351202
Orc1 removal from chromatin R-HSA-68949
Signaling by ROBO receptors R-HSA-376176
Axon guidance R-HSA-422475
Degradation of GLI2 by the proteasome R-HSA-5610783
PCP/CE pathway R-HSA-4086400
Ub-specific processing proteases R-HSA-5689880
Cell Cycle, Mitotic R-HSA-69278
Antigen processing-Cross presentation R-HSA-1236975
Cellular responses to stimuli R-HSA-8953897
S Phase R-HSA-69242
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hh mutants abrogate ligand secretion R-HSA-5387390
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Assembly of the pre-replicative complex R-HSA-68867
Regulation of RAS by GAPs R-HSA-5658442
Separation of Sister Chromatids R-HSA-2467813
Regulation of mitotic cell cycle R-HSA-453276
Disease R-HSA-1643685
Adaptive Immune System R-HSA-1280218
Signaling by Hedgehog R-HSA-5358351
G2/M Transition R-HSA-69275
Metabolism R-HSA-1430728
Hedgehog 'off' state R-HSA-5610787
Vpu mediated degradation of CD4 R-HSA-180534
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hh mutants are degraded by ERAD R-HSA-5362768
Gene expression (Transcription) R-HSA-74160
DNA Replication Pre-Initiation R-HSA-69002
Degradation of DVL R-HSA-4641258
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hedgehog ligand biogenesis R-HSA-5358346
ER-Phagosome pathway R-HSA-1236974
Disorders of transmembrane transporters R-HSA-5619115
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Neddylation R-HSA-8951664
Cell Cycle R-HSA-1640170
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Immune System R-HSA-168256
Vif-mediated degradation of APOBEC3G R-HSA-180585
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK1/MAPK3 signaling R-HSA-5684996
RNA Polymerase II Transcription R-HSA-73857
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of AXIN R-HSA-4641257
KEAP1-NFE2L2 pathway R-HSA-9755511
Deubiquitination R-HSA-5688426
Signaling by Interleukins R-HSA-449147
Metabolism of amino acids and derivatives R-HSA-71291
Nuclear events mediated by NFE2L2 R-HSA-9759194
Interleukin-1 family signaling R-HSA-446652
Signaling by NOTCH4 R-HSA-9013694
Regulation of Apoptosis R-HSA-169911
Switching of origins to a post-replicative state R-HSA-69052
Developmental Biology R-HSA-1266738
Cell Cycle R-HSA-1640170
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Axon guidance R-HSA-422475
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G1/S Transition R-HSA-69206
Nervous system development R-HSA-9675108
Mitotic G2-G2/M phases R-HSA-453274
Transcriptional regulation by RUNX2 R-HSA-8878166
Class I MHC mediated antigen processing & presentation R-HSA-983169
G2/M Transition R-HSA-69275
MAPK family signaling cascades R-HSA-5683057
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of mitotic cell cycle R-HSA-453276
Cellular responses to stimuli R-HSA-8953897
HIV Infection R-HSA-162906
Metabolism of proteins R-HSA-392499
Metabolism of polyamines R-HSA-351202
Neddylation R-HSA-8951664
Ub-specific processing proteases R-HSA-5689880
Signal Transduction R-HSA-162582
Hh mutants are degraded by ERAD R-HSA-5362768
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Programmed Cell Death R-HSA-5357801
Adaptive Immune System R-HSA-1280218
Degradation of beta-catenin by the destruction complex R-HSA-195253
Synthesis of DNA R-HSA-69239
RAF/MAP kinase cascade R-HSA-5673001
Hedgehog 'on' state R-HSA-5632684
Switching of origins to a post-replicative state R-HSA-69052
Stabilization of p53 R-HSA-69541
PTEN Regulation R-HSA-6807070
Interleukin-1 family signaling R-HSA-446652
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog ligand biogenesis R-HSA-5358346
Defective CFTR causes cystic fibrosis R-HSA-5678895
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Disease R-HSA-1643685
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Interleukin-1 signaling R-HSA-9020702
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Transport of small molecules R-HSA-382551
Cytokine Signaling in Immune system R-HSA-1280215
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
G2/M Checkpoints R-HSA-69481
G1/S DNA Damage Checkpoints R-HSA-69615
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
ER-Phagosome pathway R-HSA-1236974
Regulation of expression of SLITs and ROBOs R-HSA-9010553
ABC-family proteins mediated transport R-HSA-382556
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transcriptional regulation by RUNX1 R-HSA-8878171
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cellular response to chemical stress R-HSA-9711123
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of DVL R-HSA-4641258
Deubiquitination R-HSA-5688426
Post-translational protein modification R-HSA-597592
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Neutrophil degranulation R-HSA-6798695
Signaling by Interleukins R-HSA-449147
Signaling by ROBO receptors R-HSA-376176
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vif-mediated degradation of APOBEC3G R-HSA-180585
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Degradation of GLI2 by the proteasome R-HSA-5610783
Host Interactions of HIV factors R-HSA-162909
DNA Replication Pre-Initiation R-HSA-69002
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog 'off' state R-HSA-5610787
Cell Cycle, Mitotic R-HSA-69278
Activation of NF-kappaB in B cells R-HSA-1169091
Immune System R-HSA-168256
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Degradation of AXIN R-HSA-4641257
RNA Polymerase II Transcription R-HSA-73857
Vpu mediated degradation of CD4 R-HSA-180534
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH R-HSA-157118
Apoptosis R-HSA-109581
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism R-HSA-1430728
p53-Independent DNA Damage Response R-HSA-69610
Separation of Sister Chromatids R-HSA-2467813
Regulation of RAS by GAPs R-HSA-5658442
PCP/CE pathway R-HSA-4086400
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Mitotic Anaphase R-HSA-68882
Mitotic Metaphase and Anaphase R-HSA-2555396
Transcriptional regulation by RUNX3 R-HSA-8878159
TCR signaling R-HSA-202403
Signaling by the B Cell Receptor (BCR) R-HSA-983705
S Phase R-HSA-69242
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Metabolism of amino acids and derivatives R-HSA-71291
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cell Cycle Checkpoints R-HSA-69620
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of RNA R-HSA-8953854
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
MAPK1/MAPK3 signaling R-HSA-5684996
ABC transporter disorders R-HSA-5619084
PIP3 activates AKT signaling R-HSA-1257604
KEAP1-NFE2L2 pathway R-HSA-9755511
Innate Immune System R-HSA-168249
Signaling by WNT R-HSA-195721
FCERI mediated NF-kB activation R-HSA-2871837
DNA Replication R-HSA-69306
Antigen processing-Cross presentation R-HSA-1236975
M Phase R-HSA-68886
Negative regulation of NOTCH4 signaling R-HSA-9604323
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of Apoptosis R-HSA-169911
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of RUNX2 expression and activity R-HSA-8939902
Downstream TCR signaling R-HSA-202424
Cellular responses to stress R-HSA-2262752
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Dependent G1 DNA Damage Response R-HSA-69563
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic G1 phase and G1/S transition R-HSA-453279
Nuclear events mediated by NFE2L2 R-HSA-9759194
TCF dependent signaling in response to WNT R-HSA-201681
UCH proteinases R-HSA-5689603
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by NOTCH4 R-HSA-9013694
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Hedgehog R-HSA-5358351
Orc1 removal from chromatin R-HSA-68949
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of PTEN stability and activity R-HSA-8948751
Generic Transcription Pathway R-HSA-212436
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular response to hypoxia R-HSA-1234174
Intracellular signaling by second messengers R-HSA-9006925
Beta-catenin independent WNT signaling R-HSA-3858494
Cyclin E associated events during G1/S transition R-HSA-69202

Expression Atlas ENSG00000008018
NCBI gene (formerly Entrezgene) 5689
GeneCards 9537
HGNC Symbol HGNC:9537
MIM gene 602017
MIM morbid 620038
UniProtKB Gene Name P20618
WikiGene 5689
Gene: PSMC5
Ensembl ID : ENSG00000087191
Description: proteasome 26S subunit, ATPase 5
Gene Synonyms: P45,P45/SUG,RPT6,S8,SUG-1,SUG1,TBP10,TRIP1
5 APIs:
219 Possible Orthologues:

G1/S Transition R-HSA-69206
G2/M Checkpoints R-HSA-69481
Hedgehog 'on' state R-HSA-5632684
S Phase R-HSA-69242
Degradation of DVL R-HSA-4641258
Signaling by NOTCH R-HSA-157118
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
TCR signaling R-HSA-202403
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
MAPK family signaling cascades R-HSA-5683057
UCH proteinases R-HSA-5689603
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Deubiquitination R-HSA-5688426
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Metabolism of amino acids and derivatives R-HSA-71291
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular responses to stimuli R-HSA-8953897
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
ABC-family proteins mediated transport R-HSA-382556
Mitotic Metaphase and Anaphase R-HSA-2555396
Cell Cycle, Mitotic R-HSA-69278
Cytokine Signaling in Immune system R-HSA-1280215
Generic Transcription Pathway R-HSA-212436
Degradation of DVL R-HSA-4641258
Post-translational protein modification R-HSA-597592
Cellular response to hypoxia R-HSA-1234174
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Neddylation R-HSA-8951664
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
C-type lectin receptors (CLRs) R-HSA-5621481
Disease R-HSA-1643685
Degradation of GLI1 by the proteasome R-HSA-5610780
G2/M Transition R-HSA-69275
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of Apoptosis R-HSA-169911
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK6/MAPK4 signaling R-HSA-5687128
Disorders of transmembrane transporters R-HSA-5619115
Signaling by NOTCH4 R-HSA-9013694
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 family signaling R-HSA-446652
Cell Cycle R-HSA-1640170
Programmed Cell Death R-HSA-5357801
Regulation of RAS by GAPs R-HSA-5658442
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hedgehog 'on' state R-HSA-5632684
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by ROBO receptors R-HSA-376176
Mitotic Anaphase R-HSA-68882
Regulation of RUNX3 expression and activity R-HSA-8941858
Negative regulation of NOTCH4 signaling R-HSA-9604323
DNA Replication R-HSA-69306
Degradation of AXIN R-HSA-4641257
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of RUNX2 expression and activity R-HSA-8939902
Beta-catenin independent WNT signaling R-HSA-3858494
Apoptosis R-HSA-109581
p53-Independent DNA Damage Response R-HSA-69610
Degradation of beta-catenin by the destruction complex R-HSA-195253
Gene expression (Transcription) R-HSA-74160
Signaling by Hedgehog R-HSA-5358351
Cyclin E associated events during G1/S transition R-HSA-69202
Assembly of the pre-replicative complex R-HSA-68867
Interleukin-1 signaling R-HSA-9020702
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by the B Cell Receptor (BCR) R-HSA-983705
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular response to chemical stress R-HSA-9711123
Orc1 removal from chromatin R-HSA-68949
Metabolism of RNA R-HSA-8953854
Transcriptional regulation by RUNX2 R-HSA-8878166
PIP3 activates AKT signaling R-HSA-1257604
Hh mutants are degraded by ERAD R-HSA-5362768
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ABC transporter disorders R-HSA-5619084
ER-Phagosome pathway R-HSA-1236974
MAPK1/MAPK3 signaling R-HSA-5684996
Host Interactions of HIV factors R-HSA-162909
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX1 R-HSA-8878171
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Checkpoints R-HSA-69481
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular responses to stress R-HSA-2262752
HIV Infection R-HSA-162906
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by NOTCH R-HSA-157118
Stabilization of p53 R-HSA-69541
Immune System R-HSA-168256
Metabolism of proteins R-HSA-392499
Developmental Biology R-HSA-1266738
Innate Immune System R-HSA-168249
Synthesis of DNA R-HSA-69239
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants abrogate ligand secretion R-HSA-5387390
S Phase R-HSA-69242
KEAP1-NFE2L2 pathway R-HSA-9755511
Defective CFTR causes cystic fibrosis R-HSA-5678895
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle Checkpoints R-HSA-69620
Adaptive Immune System R-HSA-1280218
Metabolism R-HSA-1430728
PTEN Regulation R-HSA-6807070
Switching of origins to a post-replicative state R-HSA-69052
G1/S DNA Damage Checkpoints R-HSA-69615
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Asymmetric localization of PCP proteins R-HSA-4608870
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
DNA Replication Pre-Initiation R-HSA-69002
Infectious disease R-HSA-5663205
PCP/CE pathway R-HSA-4086400
FCERI mediated NF-kB activation R-HSA-2871837
Activation of NF-kappaB in B cells R-HSA-1169091
Intracellular signaling by second messengers R-HSA-9006925
RAF/MAP kinase cascade R-HSA-5673001
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Nuclear events mediated by NFE2L2 R-HSA-9759194
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G1 phase and G1/S transition R-HSA-453279
Transport of small molecules R-HSA-382551
Downstream TCR signaling R-HSA-202424
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of mitotic cell cycle R-HSA-453276
Signaling by WNT R-HSA-195721
Metabolism of polyamines R-HSA-351202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Ub-specific processing proteases R-HSA-5689880
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by Interleukins R-HSA-449147
RNA Polymerase II Transcription R-HSA-73857
Separation of Sister Chromatids R-HSA-2467813
Mitotic G2-G2/M phases R-HSA-453274
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hedgehog 'off' state R-HSA-5610787
TCF dependent signaling in response to WNT R-HSA-201681
M Phase R-HSA-68886
Class I MHC mediated antigen processing & presentation R-HSA-983169
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Deubiquitination R-HSA-5688426
Programmed Cell Death R-HSA-5357801
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of GLI2 by the proteasome R-HSA-5610783
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Nuclear events mediated by NFE2L2 R-HSA-9759194
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Signaling by Interleukins R-HSA-449147
HIV Infection R-HSA-162906
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism R-HSA-1430728
Ub-specific processing proteases R-HSA-5689880
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog 'off' state R-HSA-5610787
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cell Cycle R-HSA-1640170
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Defective CFTR causes cystic fibrosis R-HSA-5678895
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog ligand biogenesis R-HSA-5358346
Transport of small molecules R-HSA-382551
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cyclin E associated events during G1/S transition R-HSA-69202
Vpu mediated degradation of CD4 R-HSA-180534
Hh mutants abrogate ligand secretion R-HSA-5387390
Downstream TCR signaling R-HSA-202424
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX1 R-HSA-8878171
TCR signaling R-HSA-202403
Synthesis of DNA R-HSA-69239
Signaling by NOTCH R-HSA-157118
Cellular responses to stress R-HSA-2262752
FCERI mediated NF-kB activation R-HSA-2871837
Beta-catenin independent WNT signaling R-HSA-3858494
Neddylation R-HSA-8951664
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX3 R-HSA-8878159
Gene expression (Transcription) R-HSA-74160
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Post-translational protein modification R-HSA-597592
p53-Dependent G1 DNA Damage Response R-HSA-69563
PCP/CE pathway R-HSA-4086400
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
DNA Replication R-HSA-69306
G2/M Transition R-HSA-69275
Stabilization of p53 R-HSA-69541
Signaling by WNT R-HSA-195721
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Assembly of the pre-replicative complex R-HSA-68867
Antigen processing-Cross presentation R-HSA-1236975
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of AXIN R-HSA-4641257
Disorders of transmembrane transporters R-HSA-5619115
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Separation of Sister Chromatids R-HSA-2467813
Metabolism of amino acids and derivatives R-HSA-71291
G2/M Checkpoints R-HSA-69481
G1/S DNA Damage Checkpoints R-HSA-69615
Intracellular signaling by second messengers R-HSA-9006925
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of polyamines R-HSA-351202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of mitotic cell cycle R-HSA-453276
M Phase R-HSA-68886
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI1 by the proteasome R-HSA-5610780
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Disease R-HSA-1643685
KEAP1-NFE2L2 pathway R-HSA-9755511
Orc1 removal from chromatin R-HSA-68949
UCH proteinases R-HSA-5689603
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK6/MAPK4 signaling R-HSA-5687128
Metabolism of RNA R-HSA-8953854
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular response to hypoxia R-HSA-1234174
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hedgehog 'on' state R-HSA-5632684
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
ABC-family proteins mediated transport R-HSA-382556
Regulation of RAS by GAPs R-HSA-5658442
Immune System R-HSA-168256
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular responses to stimuli R-HSA-8953897
ER-Phagosome pathway R-HSA-1236974
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Class I MHC mediated antigen processing & presentation R-HSA-983169
Switching of origins to a post-replicative state R-HSA-69052
Metabolism of proteins R-HSA-392499
Infectious disease R-HSA-5663205
Mitotic Anaphase R-HSA-68882
RNA Polymerase II Transcription R-HSA-73857
Interleukin-1 family signaling R-HSA-446652
Mitotic Metaphase and Anaphase R-HSA-2555396
Cell Cycle Checkpoints R-HSA-69620
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Adaptive Immune System R-HSA-1280218
Vif-mediated degradation of APOBEC3G R-HSA-180585
Apoptosis R-HSA-109581
G1/S Transition R-HSA-69206
MAPK1/MAPK3 signaling R-HSA-5684996
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by ROBO receptors R-HSA-376176
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of Apoptosis R-HSA-169911
Regulation of RUNX3 expression and activity R-HSA-8941858
DNA Replication Pre-Initiation R-HSA-69002
PTEN Regulation R-HSA-6807070
Cellular response to chemical stress R-HSA-9711123
Interleukin-1 signaling R-HSA-9020702
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of PTEN stability and activity R-HSA-8948751
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Generic Transcription Pathway R-HSA-212436
S Phase R-HSA-69242
Axon guidance R-HSA-422475
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Developmental Biology R-HSA-1266738
Host Interactions of HIV factors R-HSA-162909
Mitotic G2-G2/M phases R-HSA-453274
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Mitotic G1 phase and G1/S transition R-HSA-453279
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
PIP3 activates AKT signaling R-HSA-1257604
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of DVL R-HSA-4641258
Nervous system development R-HSA-9675108
p53-Independent DNA Damage Response R-HSA-69610
Negative regulation of NOTCH4 signaling R-HSA-9604323
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
ABC-family proteins mediated transport R-HSA-382556
Infectious disease R-HSA-5663205
Metabolism R-HSA-1430728
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of RUNX3 expression and activity R-HSA-8941858
Disease R-HSA-1643685
Transport of small molecules R-HSA-382551
Mitotic Metaphase and Anaphase R-HSA-2555396
ABC transporter disorders R-HSA-5619084
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Innate Immune System R-HSA-168249
G2/M Checkpoints R-HSA-69481
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
ER-Phagosome pathway R-HSA-1236974
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of RAS by GAPs R-HSA-5658442
RAF/MAP kinase cascade R-HSA-5673001
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by WNT R-HSA-195721
Stabilization of p53 R-HSA-69541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Activation of NF-kappaB in B cells R-HSA-1169091
Axon guidance R-HSA-422475
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hedgehog ligand biogenesis R-HSA-5358346
Cytokine Signaling in Immune system R-HSA-1280215
Vpu mediated degradation of CD4 R-HSA-180534
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX2 R-HSA-8878166
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
RNA Polymerase II Transcription R-HSA-73857
Degradation of DVL R-HSA-4641258
Mitotic Anaphase R-HSA-68882
CLEC7A (Dectin-1) signaling R-HSA-5607764
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G1/S DNA Damage Checkpoints R-HSA-69615
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream TCR signaling R-HSA-202424
Immune System R-HSA-168256
Degradation of beta-catenin by the destruction complex R-HSA-195253
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
MAPK family signaling cascades R-HSA-5683057
Nervous system development R-HSA-9675108
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin E associated events during G1/S transition R-HSA-69202
Disorders of transmembrane transporters R-HSA-5619115
Regulation of mitotic cell cycle R-HSA-453276
Developmental Biology R-HSA-1266738
Hedgehog 'off' state R-HSA-5610787
Adaptive Immune System R-HSA-1280218
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PCP/CE pathway R-HSA-4086400
Assembly of the pre-replicative complex R-HSA-68867
Signaling by Interleukins R-HSA-449147
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog 'on' state R-HSA-5632684
UCH proteinases R-HSA-5689603
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Independent DNA Damage Response R-HSA-69610
TCR signaling R-HSA-202403
Regulation of expression of SLITs and ROBOs R-HSA-9010553
C-type lectin receptors (CLRs) R-HSA-5621481
Generic Transcription Pathway R-HSA-212436
Deubiquitination R-HSA-5688426
Cellular responses to stress R-HSA-2262752
Beta-catenin independent WNT signaling R-HSA-3858494
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Asymmetric localization of PCP proteins R-HSA-4608870
Transcriptional regulation by RUNX3 R-HSA-8878159
HIV Infection R-HSA-162906
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of polyamines R-HSA-351202
Cell Cycle Checkpoints R-HSA-69620
Defective CFTR causes cystic fibrosis R-HSA-5678895
Neddylation R-HSA-8951664
Signaling by NOTCH R-HSA-157118
Degradation of AXIN R-HSA-4641257
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of RNA R-HSA-8953854
Signaling by Hedgehog R-HSA-5358351
Separation of Sister Chromatids R-HSA-2467813
Switching of origins to a post-replicative state R-HSA-69052
Apoptosis R-HSA-109581
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Post-translational protein modification R-HSA-597592
Negative regulation of NOTCH4 signaling R-HSA-9604323
G1/S Transition R-HSA-69206
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Synthesis of DNA R-HSA-69239
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G2-G2/M phases R-HSA-453274
PTEN Regulation R-HSA-6807070
Regulation of Apoptosis R-HSA-169911
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of proteins R-HSA-392499
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Replication R-HSA-69306
Ub-specific processing proteases R-HSA-5689880
Degradation of GLI2 by the proteasome R-HSA-5610783
Vif-mediated degradation of APOBEC3G R-HSA-180585
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Nuclear events mediated by NFE2L2 R-HSA-9759194
Gene expression (Transcription) R-HSA-74160
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular responses to stimuli R-HSA-8953897
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX2 expression and activity R-HSA-8939902
G2/M Transition R-HSA-69275
Signaling by ROBO receptors R-HSA-376176
Mitotic G1 phase and G1/S transition R-HSA-453279
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism of amino acids and derivatives R-HSA-71291
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX1 R-HSA-8878171
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
S Phase R-HSA-69242
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Antigen processing-Cross presentation R-HSA-1236975
TCF dependent signaling in response to WNT R-HSA-201681
M Phase R-HSA-68886
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of GLI1 by the proteasome R-HSA-5610780
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular response to hypoxia R-HSA-1234174
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle, Mitotic R-HSA-69278
PIP3 activates AKT signaling R-HSA-1257604
Host Interactions of HIV factors R-HSA-162909
FCERI mediated NF-kB activation R-HSA-2871837
Interleukin-1 signaling R-HSA-9020702
Signal Transduction R-HSA-162582
Disorders of transmembrane transporters R-HSA-5619115
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Transcriptional regulation by RUNX3 R-HSA-8878159
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of polyamines R-HSA-351202
Assembly of the pre-replicative complex R-HSA-68867
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Orc1 removal from chromatin R-HSA-68949
MAPK family signaling cascades R-HSA-5683057
ER-Phagosome pathway R-HSA-1236974
Gene expression (Transcription) R-HSA-74160
UCH proteinases R-HSA-5689603
Neddylation R-HSA-8951664
Degradation of AXIN R-HSA-4641257
MAPK6/MAPK4 signaling R-HSA-5687128
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stress R-HSA-2262752
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hedgehog 'on' state R-HSA-5632684
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Asymmetric localization of PCP proteins R-HSA-4608870
Synthesis of DNA R-HSA-69239
Degradation of DVL R-HSA-4641258
Hh mutants abrogate ligand secretion R-HSA-5387390
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Immune System R-HSA-168256
Signaling by NOTCH R-HSA-157118
Mitotic G2-G2/M phases R-HSA-453274
Metabolism R-HSA-1430728
MAPK1/MAPK3 signaling R-HSA-5684996
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of RUNX2 expression and activity R-HSA-8939902
Cell Cycle R-HSA-1640170
RAF/MAP kinase cascade R-HSA-5673001
Cellular response to hypoxia R-HSA-1234174
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by NOTCH4 R-HSA-9013694
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signal Transduction R-HSA-162582
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of mitotic cell cycle R-HSA-453276
ABC transporter disorders R-HSA-5619084
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vif-mediated degradation of APOBEC3G R-HSA-180585
TCR signaling R-HSA-202403
Regulation of Apoptosis R-HSA-169911
S Phase R-HSA-69242
Signaling by Interleukins R-HSA-449147
DNA Replication R-HSA-69306
Class I MHC mediated antigen processing & presentation R-HSA-983169
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of proteins R-HSA-392499
Cyclin E associated events during G1/S transition R-HSA-69202
Negative regulation of NOTCH4 signaling R-HSA-9604323
Disease R-HSA-1643685
Signaling by Hedgehog R-HSA-5358351
Mitotic Metaphase and Anaphase R-HSA-2555396
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
HIV Infection R-HSA-162906
Degradation of GLI1 by the proteasome R-HSA-5610780
Programmed Cell Death R-HSA-5357801
Metabolism of RNA R-HSA-8953854
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Degradation of beta-catenin by the destruction complex R-HSA-195253
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Transcriptional regulation by RUNX1 R-HSA-8878171
Post-translational protein modification R-HSA-597592
Regulation of RAS by GAPs R-HSA-5658442
Deubiquitination R-HSA-5688426
Adaptive Immune System R-HSA-1280218
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ub-specific processing proteases R-HSA-5689880
RNA Polymerase II Transcription R-HSA-73857
Nervous system development R-HSA-9675108
Signaling by ROBO receptors R-HSA-376176
Cell Cycle, Mitotic R-HSA-69278
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Infectious disease R-HSA-5663205
Generic Transcription Pathway R-HSA-212436
Interleukin-1 family signaling R-HSA-446652
M Phase R-HSA-68886
Hh mutants are degraded by ERAD R-HSA-5362768
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular responses to stimuli R-HSA-8953897
Cell Cycle Checkpoints R-HSA-69620
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RUNX3 expression and activity R-HSA-8941858
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by WNT R-HSA-195721
PCP/CE pathway R-HSA-4086400
PIP3 activates AKT signaling R-HSA-1257604
Cellular response to chemical stress R-HSA-9711123
Vpu mediated degradation of CD4 R-HSA-180534
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of PTEN stability and activity R-HSA-8948751
Stabilization of p53 R-HSA-69541
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Transition R-HSA-69275
Regulation of expression of SLITs and ROBOs R-HSA-9010553
NIK-->noncanonical NF-kB signaling R-HSA-5676590
p53-Independent DNA Damage Response R-HSA-69610
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of amino acids and derivatives R-HSA-71291
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Mitotic Anaphase R-HSA-68882
Downstream TCR signaling R-HSA-202424
Host Interactions of HIV factors R-HSA-162909
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog 'off' state R-HSA-5610787
CLEC7A (Dectin-1) signaling R-HSA-5607764
Antigen processing-Cross presentation R-HSA-1236975
FCERI mediated NF-kB activation R-HSA-2871837
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
KEAP1-NFE2L2 pathway R-HSA-9755511
Cytokine Signaling in Immune system R-HSA-1280215
Hedgehog ligand biogenesis R-HSA-5358346
C-type lectin receptors (CLRs) R-HSA-5621481
Switching of origins to a post-replicative state R-HSA-69052
Apoptosis R-HSA-109581
Transport of small molecules R-HSA-382551
G1/S Transition R-HSA-69206
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Transcriptional regulation by RUNX2 R-HSA-8878166
Interleukin-1 signaling R-HSA-9020702
Innate Immune System R-HSA-168249
DNA Replication Pre-Initiation R-HSA-69002
PTEN Regulation R-HSA-6807070
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
G1/S DNA Damage Checkpoints R-HSA-69615
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Nervous system development R-HSA-9675108
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
M Phase R-HSA-68886
Degradation of GLI1 by the proteasome R-HSA-5610780
Apoptosis R-HSA-109581
PCP/CE pathway R-HSA-4086400
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
DNA Replication Pre-Initiation R-HSA-69002
Degradation of DVL R-HSA-4641258
Mitotic G1 phase and G1/S transition R-HSA-453279
TCR signaling R-HSA-202403
p53-Dependent G1 DNA Damage Response R-HSA-69563
Axon guidance R-HSA-422475
ABC transporter disorders R-HSA-5619084
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Generic Transcription Pathway R-HSA-212436
Cell Cycle Checkpoints R-HSA-69620
PTEN Regulation R-HSA-6807070
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent DNA Damage Response R-HSA-69610
Asymmetric localization of PCP proteins R-HSA-4608870
Hh mutants abrogate ligand secretion R-HSA-5387390
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Stabilization of p53 R-HSA-69541
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
ABC-family proteins mediated transport R-HSA-382556
G2/M Transition R-HSA-69275
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Hedgehog R-HSA-5358351
Hedgehog 'on' state R-HSA-5632684
Immune System R-HSA-168256
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of PTEN stability and activity R-HSA-8948751
RAF/MAP kinase cascade R-HSA-5673001
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of AXIN R-HSA-4641257
Metabolism of amino acids and derivatives R-HSA-71291
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vpu mediated degradation of CD4 R-HSA-180534
G1/S DNA Damage Checkpoints R-HSA-69615
RNA Polymerase II Transcription R-HSA-73857
Cellular response to chemical stress R-HSA-9711123
Downstream TCR signaling R-HSA-202424
Regulation of RUNX2 expression and activity R-HSA-8939902
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by NOTCH R-HSA-157118
Signaling by the B Cell Receptor (BCR) R-HSA-983705
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of mitotic cell cycle R-HSA-453276
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Class I MHC mediated antigen processing & presentation R-HSA-983169
Programmed Cell Death R-HSA-5357801
Separation of Sister Chromatids R-HSA-2467813
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Nuclear events mediated by NFE2L2 R-HSA-9759194
Interleukin-1 signaling R-HSA-9020702
G2/M Checkpoints R-HSA-69481
Metabolism of proteins R-HSA-392499
Orc1 removal from chromatin R-HSA-68949
Defective CFTR causes cystic fibrosis R-HSA-5678895
HIV Infection R-HSA-162906
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
Cyclin E associated events during G1/S transition R-HSA-69202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of Apoptosis R-HSA-169911
Adaptive Immune System R-HSA-1280218
Disorders of transmembrane transporters R-HSA-5619115
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by ROBO receptors R-HSA-376176
Metabolism of polyamines R-HSA-351202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Assembly of the pre-replicative complex R-HSA-68867
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Innate Immune System R-HSA-168249
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Synthesis of DNA R-HSA-69239
Switching of origins to a post-replicative state R-HSA-69052
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX1 R-HSA-8878171
KEAP1-NFE2L2 pathway R-HSA-9755511
Ub-specific processing proteases R-HSA-5689880
Signaling by Interleukins R-HSA-449147
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication R-HSA-69306
Hedgehog ligand biogenesis R-HSA-5358346
Cellular responses to stress R-HSA-2262752
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by NOTCH4 R-HSA-9013694
MAPK1/MAPK3 signaling R-HSA-5684996
Transcriptional regulation by RUNX3 R-HSA-8878159
Disease R-HSA-1643685
Deubiquitination R-HSA-5688426
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of RUNX3 expression and activity R-HSA-8941858
MAPK family signaling cascades R-HSA-5683057
Intracellular signaling by second messengers R-HSA-9006925
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Negative regulation of NOTCH4 signaling R-HSA-9604323
Antigen processing-Cross presentation R-HSA-1236975
Neddylation R-HSA-8951664
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Mitotic G2-G2/M phases R-HSA-453274
ER-Phagosome pathway R-HSA-1236974
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Host Interactions of HIV factors R-HSA-162909
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cellular response to hypoxia R-HSA-1234174
Cell Cycle R-HSA-1640170
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stimuli R-HSA-8953897
Developmental Biology R-HSA-1266738
S Phase R-HSA-69242
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
Cytokine Signaling in Immune system R-HSA-1280215
Vif-mediated degradation of APOBEC3G R-HSA-180585
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of RNA R-HSA-8953854
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX2 R-HSA-8878166
G1/S Transition R-HSA-69206
Metabolism R-HSA-1430728
Transport of small molecules R-HSA-382551
Interleukin-1 family signaling R-HSA-446652
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic Anaphase R-HSA-68882
Signaling by WNT R-HSA-195721
Transcriptional regulation by RUNX1 R-HSA-8878171
G2/M Checkpoints R-HSA-69481
Downstream TCR signaling R-HSA-202424
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MAPK6/MAPK4 signaling R-HSA-5687128
Beta-catenin independent WNT signaling R-HSA-3858494
PTEN Regulation R-HSA-6807070
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hh mutants are degraded by ERAD R-HSA-5362768
Orc1 removal from chromatin R-HSA-68949
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Generic Transcription Pathway R-HSA-212436
S Phase R-HSA-69242
Ub-specific processing proteases R-HSA-5689880
Negative regulation of NOTCH4 signaling R-HSA-9604323
Stabilization of p53 R-HSA-69541
Regulation of Apoptosis R-HSA-169911
Cell Cycle Checkpoints R-HSA-69620
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of proteins R-HSA-392499
Nervous system development R-HSA-9675108
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
FCERI mediated NF-kB activation R-HSA-2871837
Nuclear events mediated by NFE2L2 R-HSA-9759194
PCP/CE pathway R-HSA-4086400
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
UCH proteinases R-HSA-5689603
Cellular responses to stimuli R-HSA-8953897
Neddylation R-HSA-8951664
M Phase R-HSA-68886
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
KEAP1-NFE2L2 pathway R-HSA-9755511
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Vpu mediated degradation of CD4 R-HSA-180534
Antigen processing-Cross presentation R-HSA-1236975
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of AXIN R-HSA-4641257
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of RAS by GAPs R-HSA-5658442
Immune System R-HSA-168256
DNA Replication R-HSA-69306
Axon guidance R-HSA-422475
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signal Transduction R-HSA-162582
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of DVL R-HSA-4641258
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
ER-Phagosome pathway R-HSA-1236974
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Intracellular signaling by second messengers R-HSA-9006925
HIV Infection R-HSA-162906
Cell Cycle, Mitotic R-HSA-69278
RAF/MAP kinase cascade R-HSA-5673001
Disease R-HSA-1643685
Signaling by Interleukins R-HSA-449147
Metabolism of RNA R-HSA-8953854
G1/S Transition R-HSA-69206
G2/M Transition R-HSA-69275
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Synthesis of DNA R-HSA-69239
Defective CFTR causes cystic fibrosis R-HSA-5678895
Metabolism of polyamines R-HSA-351202
Hedgehog 'off' state R-HSA-5610787
Assembly of the pre-replicative complex R-HSA-68867
Mitotic Metaphase and Anaphase R-HSA-2555396
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
TCF dependent signaling in response to WNT R-HSA-201681
C-type lectin receptors (CLRs) R-HSA-5621481
ABC transporter disorders R-HSA-5619084
Disorders of transmembrane transporters R-HSA-5619115
Signaling by NOTCH R-HSA-157118
Cyclin E associated events during G1/S transition R-HSA-69202
G1/S DNA Damage Checkpoints R-HSA-69615
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Separation of Sister Chromatids R-HSA-2467813
Metabolism R-HSA-1430728
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by ROBO receptors R-HSA-376176
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Interleukin-1 signaling R-HSA-9020702
Mitotic Anaphase R-HSA-68882
ABC-family proteins mediated transport R-HSA-382556
Programmed Cell Death R-HSA-5357801
MAPK family signaling cascades R-HSA-5683057
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of PTEN stability and activity R-HSA-8948751
Cellular response to chemical stress R-HSA-9711123
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by NOTCH4 R-HSA-9013694
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Independent DNA Damage Response R-HSA-69610
Host Interactions of HIV factors R-HSA-162909
Cellular responses to stress R-HSA-2262752
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transport of small molecules R-HSA-382551
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Hedgehog R-HSA-5358351
Metabolism of amino acids and derivatives R-HSA-71291
Transcriptional regulation by RUNX3 R-HSA-8878159
Mitotic G2-G2/M phases R-HSA-453274
Asymmetric localization of PCP proteins R-HSA-4608870
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to hypoxia R-HSA-1234174
Developmental Biology R-HSA-1266738
Regulation of RUNX2 expression and activity R-HSA-8939902
Adaptive Immune System R-HSA-1280218
Post-translational protein modification R-HSA-597592
Apoptosis R-HSA-109581
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog ligand biogenesis R-HSA-5358346
Gene expression (Transcription) R-HSA-74160
TCR signaling R-HSA-202403
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hh mutants abrogate ligand secretion R-HSA-5387390
Activation of NF-kappaB in B cells R-HSA-1169091
Class I MHC mediated antigen processing & presentation R-HSA-983169
Interleukin-1 family signaling R-HSA-446652
Degradation of GLI2 by the proteasome R-HSA-5610783
Deubiquitination R-HSA-5688426
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
HIV Infection R-HSA-162906
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of polyamines R-HSA-351202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Class I MHC mediated antigen processing & presentation R-HSA-983169
ABC-family proteins mediated transport R-HSA-382556
Metabolism R-HSA-1430728
PCP/CE pathway R-HSA-4086400
FCERI mediated NF-kB activation R-HSA-2871837
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Gene expression (Transcription) R-HSA-74160
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK6/MAPK4 signaling R-HSA-5687128
G2/M Transition R-HSA-69275
Transport of small molecules R-HSA-382551
Cell Cycle Checkpoints R-HSA-69620
Stabilization of p53 R-HSA-69541
Orc1 removal from chromatin R-HSA-68949
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Ub-specific processing proteases R-HSA-5689880
Degradation of AXIN R-HSA-4641257
Developmental Biology R-HSA-1266738
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Mitotic G2-G2/M phases R-HSA-453274
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hedgehog 'on' state R-HSA-5632684
Degradation of DVL R-HSA-4641258
Cell Cycle R-HSA-1640170
Cellular responses to stimuli R-HSA-8953897
Post-translational protein modification R-HSA-597592
Vpu mediated degradation of CD4 R-HSA-180534
MAPK1/MAPK3 signaling R-HSA-5684996
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
UCH proteinases R-HSA-5689603
Metabolism of amino acids and derivatives R-HSA-71291
Disease R-HSA-1643685
Interleukin-1 signaling R-HSA-9020702
Signaling by Interleukins R-HSA-449147
Negative regulation of NOTCH4 signaling R-HSA-9604323
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
KEAP1-NFE2L2 pathway R-HSA-9755511
Neddylation R-HSA-8951664
Regulation of RUNX2 expression and activity R-HSA-8939902
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of proteins R-HSA-392499
Infectious disease R-HSA-5663205
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Disorders of transmembrane transporters R-HSA-5619115
Synthesis of DNA R-HSA-69239
Regulation of PTEN stability and activity R-HSA-8948751
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Host Interactions of HIV factors R-HSA-162909
Hh mutants are degraded by ERAD R-HSA-5362768
ABC transporter disorders R-HSA-5619084
Signaling by ROBO receptors R-HSA-376176
Axon guidance R-HSA-422475
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of mitotic cell cycle R-HSA-453276
TCR signaling R-HSA-202403
Mitotic Metaphase and Anaphase R-HSA-2555396
p53-Independent DNA Damage Response R-HSA-69610
Cellular responses to stress R-HSA-2262752
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Deubiquitination R-HSA-5688426
Separation of Sister Chromatids R-HSA-2467813
M Phase R-HSA-68886
Hedgehog 'off' state R-HSA-5610787
PTEN Regulation R-HSA-6807070
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX3 R-HSA-8878159
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
RAF/MAP kinase cascade R-HSA-5673001
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of expression of SLITs and ROBOs R-HSA-9010553
C-type lectin receptors (CLRs) R-HSA-5621481
Apoptosis R-HSA-109581
Adaptive Immune System R-HSA-1280218
DNA Replication R-HSA-69306
G1/S DNA Damage Checkpoints R-HSA-69615
Mitotic Anaphase R-HSA-68882
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cellular response to hypoxia R-HSA-1234174
TCF dependent signaling in response to WNT R-HSA-201681
Cytokine Signaling in Immune system R-HSA-1280215
Downstream TCR signaling R-HSA-202424
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Intracellular signaling by second messengers R-HSA-9006925
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX2 R-HSA-8878166
Antigen processing-Cross presentation R-HSA-1236975
Cellular response to chemical stress R-HSA-9711123
Nervous system development R-HSA-9675108
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of beta-catenin by the destruction complex R-HSA-195253
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by WNT R-HSA-195721
Regulation of RUNX3 expression and activity R-HSA-8941858
Immune System R-HSA-168256
G1/S Transition R-HSA-69206
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
MAPK family signaling cascades R-HSA-5683057
DNA Replication Pre-Initiation R-HSA-69002
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 family signaling R-HSA-446652
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH4 R-HSA-9013694
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Switching of origins to a post-replicative state R-HSA-69052
Assembly of the pre-replicative complex R-HSA-68867
G2/M Checkpoints R-HSA-69481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX1 R-HSA-8878171
Hedgehog ligand biogenesis R-HSA-5358346
Cell Cycle, Mitotic R-HSA-69278
Regulation of Apoptosis R-HSA-169911
Beta-catenin independent WNT signaling R-HSA-3858494
Nuclear events mediated by NFE2L2 R-HSA-9759194
Programmed Cell Death R-HSA-5357801
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G1 phase and G1/S transition R-HSA-453279
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI2 by the proteasome R-HSA-5610783
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cellular responses to stimuli R-HSA-8953897
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-1 signaling R-HSA-9020702
Hedgehog 'off' state R-HSA-5610787
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Infectious disease R-HSA-5663205
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Degradation of beta-catenin by the destruction complex R-HSA-195253
Post-translational protein modification R-HSA-597592
Cellular response to chemical stress R-HSA-9711123
M Phase R-HSA-68886
p53-Independent DNA Damage Response R-HSA-69610
G2/M Checkpoints R-HSA-69481
Regulation of Apoptosis R-HSA-169911
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by ROBO receptors R-HSA-376176
Cytokine Signaling in Immune system R-HSA-1280215
G2/M Transition R-HSA-69275
FCERI mediated NF-kB activation R-HSA-2871837
Asymmetric localization of PCP proteins R-HSA-4608870
UCH proteinases R-HSA-5689603
Signaling by NOTCH4 R-HSA-9013694
Downstream TCR signaling R-HSA-202424
Gene expression (Transcription) R-HSA-74160
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hh mutants abrogate ligand secretion R-HSA-5387390
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Activation of NF-kappaB in B cells R-HSA-1169091
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by NOTCH R-HSA-157118
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Innate Immune System R-HSA-168249
Defective CFTR causes cystic fibrosis R-HSA-5678895
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog ligand biogenesis R-HSA-5358346
Adaptive Immune System R-HSA-1280218
Signaling by the B Cell Receptor (BCR) R-HSA-983705
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism R-HSA-1430728
PTEN Regulation R-HSA-6807070
MAPK family signaling cascades R-HSA-5683057
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of RNA R-HSA-8953854
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX3 R-HSA-8878159
Axon guidance R-HSA-422475
Assembly of the pre-replicative complex R-HSA-68867
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Apoptosis R-HSA-109581
Signaling by WNT R-HSA-195721
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of PTEN stability and activity R-HSA-8948751
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S DNA Damage Checkpoints R-HSA-69615
TCF dependent signaling in response to WNT R-HSA-201681
Transcriptional regulation by RUNX1 R-HSA-8878171
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Class I MHC mediated antigen processing & presentation R-HSA-983169
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular responses to stress R-HSA-2262752
TCR signaling R-HSA-202403
DNA Replication R-HSA-69306
Cellular response to hypoxia R-HSA-1234174
Metabolism of proteins R-HSA-392499
HIV Infection R-HSA-162906
Signaling by Hedgehog R-HSA-5358351
Cell Cycle Checkpoints R-HSA-69620
Vif-mediated degradation of APOBEC3G R-HSA-180585
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Switching of origins to a post-replicative state R-HSA-69052
S Phase R-HSA-69242
Programmed Cell Death R-HSA-5357801
Mitotic G2-G2/M phases R-HSA-453274
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Interleukin-1 family signaling R-HSA-446652
Degradation of AXIN R-HSA-4641257
RNA Polymerase II Transcription R-HSA-73857
Deubiquitination R-HSA-5688426
RAF/MAP kinase cascade R-HSA-5673001
Transport of small molecules R-HSA-382551
Signaling by Interleukins R-HSA-449147
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Metabolism of amino acids and derivatives R-HSA-71291
ABC transporter disorders R-HSA-5619084
PCP/CE pathway R-HSA-4086400
Degradation of GLI1 by the proteasome R-HSA-5610780
Stabilization of p53 R-HSA-69541
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RUNX2 expression and activity R-HSA-8939902
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Synthesis of DNA R-HSA-69239
Intracellular signaling by second messengers R-HSA-9006925
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Developmental Biology R-HSA-1266738
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of RAS by GAPs R-HSA-5658442
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Ub-specific processing proteases R-HSA-5689880
Signal Transduction R-HSA-162582
ABC-family proteins mediated transport R-HSA-382556
DNA Replication Pre-Initiation R-HSA-69002
Disease R-HSA-1643685
Separation of Sister Chromatids R-HSA-2467813
Disorders of transmembrane transporters R-HSA-5619115
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hh mutants are degraded by ERAD R-HSA-5362768
Host Interactions of HIV factors R-HSA-162909
Regulation of mitotic cell cycle R-HSA-453276
MAPK1/MAPK3 signaling R-HSA-5684996
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Neddylation R-HSA-8951664
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of RUNX3 expression and activity R-HSA-8941858
Mitotic Anaphase R-HSA-68882
G1/S Transition R-HSA-69206
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Metaphase and Anaphase R-HSA-2555396
Nervous system development R-HSA-9675108
Cell Cycle, Mitotic R-HSA-69278
ER-Phagosome pathway R-HSA-1236974
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Orc1 removal from chromatin R-HSA-68949
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Immune System R-HSA-168256
Vpu mediated degradation of CD4 R-HSA-180534
Metabolism of polyamines R-HSA-351202
PTEN Regulation R-HSA-6807070
Metabolism R-HSA-1430728
Infectious disease R-HSA-5663205
C-type lectin receptors (CLRs) R-HSA-5621481
Disease R-HSA-1643685
Mitotic Anaphase R-HSA-68882
Signaling by ROBO receptors R-HSA-376176
Immune System R-HSA-168256
Assembly of the pre-replicative complex R-HSA-68867
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular response to hypoxia R-HSA-1234174
Ub-specific processing proteases R-HSA-5689880
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX3 R-HSA-8878159
Degradation of AXIN R-HSA-4641257
Apoptosis R-HSA-109581
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by NOTCH4 R-HSA-9013694
Regulation of Apoptosis R-HSA-169911
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Axon guidance R-HSA-422475
Metabolism of amino acids and derivatives R-HSA-71291
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Interleukin-1 signaling R-HSA-9020702
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transcriptional regulation by RUNX2 R-HSA-8878166
Deubiquitination R-HSA-5688426
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 family signaling R-HSA-446652
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
ABC transporter disorders R-HSA-5619084
Signal Transduction R-HSA-162582
Cellular response to chemical stress R-HSA-9711123
Switching of origins to a post-replicative state R-HSA-69052
TCF dependent signaling in response to WNT R-HSA-201681
Cytokine Signaling in Immune system R-HSA-1280215
S Phase R-HSA-69242
Degradation of GLI2 by the proteasome R-HSA-5610783
G2/M Transition R-HSA-69275
Metabolism of RNA R-HSA-8953854
Synthesis of DNA R-HSA-69239
Hedgehog 'on' state R-HSA-5632684
DNA Replication R-HSA-69306
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by Interleukins R-HSA-449147
Cellular responses to stress R-HSA-2262752
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
ABC-family proteins mediated transport R-HSA-382556
Metabolism of proteins R-HSA-392499
MAPK6/MAPK4 signaling R-HSA-5687128
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of RUNX3 expression and activity R-HSA-8941858
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
CLEC7A (Dectin-1) signaling R-HSA-5607764
Orc1 removal from chromatin R-HSA-68949
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transcriptional regulation by RUNX1 R-HSA-8878171
Antigen processing-Cross presentation R-HSA-1236975
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Beta-catenin independent WNT signaling R-HSA-3858494
RAF/MAP kinase cascade R-HSA-5673001
Nervous system development R-HSA-9675108
Transport of small molecules R-HSA-382551
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Disorders of transmembrane transporters R-HSA-5619115
Signaling by Hedgehog R-HSA-5358351
MAPK family signaling cascades R-HSA-5683057
Hedgehog ligand biogenesis R-HSA-5358346
Stabilization of p53 R-HSA-69541
HIV Infection R-HSA-162906
Developmental Biology R-HSA-1266738
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G1/S Transition R-HSA-69206
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of RAS by GAPs R-HSA-5658442
Cell Cycle R-HSA-1640170
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog 'off' state R-HSA-5610787
ER-Phagosome pathway R-HSA-1236974
Separation of Sister Chromatids R-HSA-2467813
Mitotic G1 phase and G1/S transition R-HSA-453279
TCR signaling R-HSA-202403
G2/M Checkpoints R-HSA-69481
M Phase R-HSA-68886
Neddylation R-HSA-8951664
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear events mediated by NFE2L2 R-HSA-9759194
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Degradation of GLI1 by the proteasome R-HSA-5610780
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Vpu mediated degradation of CD4 R-HSA-180534
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hh mutants abrogate ligand secretion R-HSA-5387390
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of polyamines R-HSA-351202
Defective CFTR causes cystic fibrosis R-HSA-5678895
PCP/CE pathway R-HSA-4086400
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle, Mitotic R-HSA-69278
Adaptive Immune System R-HSA-1280218
Activation of NF-kappaB in B cells R-HSA-1169091
DNA Replication Pre-Initiation R-HSA-69002
p53-Dependent G1 DNA Damage Response R-HSA-69563
UCH proteinases R-HSA-5689603
p53-Independent DNA Damage Response R-HSA-69610
Generic Transcription Pathway R-HSA-212436
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cyclin E associated events during G1/S transition R-HSA-69202
Mitotic Metaphase and Anaphase R-HSA-2555396
Downstream TCR signaling R-HSA-202424
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of DVL R-HSA-4641258
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Innate Immune System R-HSA-168249
Regulation of mitotic cell cycle R-HSA-453276
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
Host Interactions of HIV factors R-HSA-162909
Cellular responses to stimuli R-HSA-8953897
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by NOTCH R-HSA-157118
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Asymmetric localization of PCP proteins R-HSA-4608870
Programmed Cell Death R-HSA-5357801
Metabolism of proteins R-HSA-392499
Disease R-HSA-1643685
Regulation of RUNX3 expression and activity R-HSA-8941858
RNA Polymerase II Transcription R-HSA-73857
Hedgehog ligand biogenesis R-HSA-5358346
ER-Phagosome pathway R-HSA-1236974
Signal Transduction R-HSA-162582
Signaling by NOTCH4 R-HSA-9013694
Stabilization of p53 R-HSA-69541
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of polyamines R-HSA-351202
Cyclin E associated events during G1/S transition R-HSA-69202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Assembly of the pre-replicative complex R-HSA-68867
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Degradation of GLI2 by the proteasome R-HSA-5610783
C-type lectin receptors (CLRs) R-HSA-5621481
Intracellular signaling by second messengers R-HSA-9006925
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
MAPK1/MAPK3 signaling R-HSA-5684996
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by Interleukins R-HSA-449147
MAPK family signaling cascades R-HSA-5683057
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RAF/MAP kinase cascade R-HSA-5673001
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Independent DNA Damage Response R-HSA-69610
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Mitotic Metaphase and Anaphase R-HSA-2555396
FCERI mediated NF-kB activation R-HSA-2871837
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Ub-specific processing proteases R-HSA-5689880
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism R-HSA-1430728
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Activation of NF-kappaB in B cells R-HSA-1169091
Defective CFTR causes cystic fibrosis R-HSA-5678895
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Synthesis of DNA R-HSA-69239
Metabolism of amino acids and derivatives R-HSA-71291
PIP3 activates AKT signaling R-HSA-1257604
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by Hedgehog R-HSA-5358351
Gene expression (Transcription) R-HSA-74160
Regulation of mitotic cell cycle R-HSA-453276
Nuclear events mediated by NFE2L2 R-HSA-9759194
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'off' state R-HSA-5610787
Metabolism of RNA R-HSA-8953854
KEAP1-NFE2L2 pathway R-HSA-9755511
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by WNT R-HSA-195721
Cellular response to chemical stress R-HSA-9711123
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Innate Immune System R-HSA-168249
Transport of small molecules R-HSA-382551
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
PCP/CE pathway R-HSA-4086400
Regulation of expression of SLITs and ROBOs R-HSA-9010553
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cell Cycle Checkpoints R-HSA-69620
Degradation of AXIN R-HSA-4641257
PTEN Regulation R-HSA-6807070
Neddylation R-HSA-8951664
Downstream TCR signaling R-HSA-202424
Switching of origins to a post-replicative state R-HSA-69052
DNA Replication Pre-Initiation R-HSA-69002
Beta-catenin independent WNT signaling R-HSA-3858494
MAPK6/MAPK4 signaling R-HSA-5687128
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
ABC transporter disorders R-HSA-5619084
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Disorders of transmembrane transporters R-HSA-5619115
Immune System R-HSA-168256
Apoptosis R-HSA-109581
Regulation of Apoptosis R-HSA-169911
G1/S DNA Damage Checkpoints R-HSA-69615
Hh mutants are degraded by ERAD R-HSA-5362768
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Adaptive Immune System R-HSA-1280218
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX2 R-HSA-8878166
Orc1 removal from chromatin R-HSA-68949
Infectious disease R-HSA-5663205
ABC-family proteins mediated transport R-HSA-382556
DNA Replication R-HSA-69306
Post-translational protein modification R-HSA-597592
Interleukin-1 signaling R-HSA-9020702
Degradation of GLI1 by the proteasome R-HSA-5610780
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic G2-G2/M phases R-HSA-453274
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Vif-mediated degradation of APOBEC3G R-HSA-180585
TCF dependent signaling in response to WNT R-HSA-201681
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nervous system development R-HSA-9675108
Interleukin-1 family signaling R-HSA-446652
G2/M Checkpoints R-HSA-69481
Cellular response to hypoxia R-HSA-1234174
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hh mutants abrogate ligand secretion R-HSA-5387390
CLEC7A (Dectin-1) signaling R-HSA-5607764
G1/S Transition R-HSA-69206
Regulation of RAS by GAPs R-HSA-5658442
Class I MHC mediated antigen processing & presentation R-HSA-983169
UCH proteinases R-HSA-5689603
TCR signaling R-HSA-202403
Cell Cycle, Mitotic R-HSA-69278
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of DVL R-HSA-4641258
Mitotic Anaphase R-HSA-68882
Axon guidance R-HSA-422475
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by ROBO receptors R-HSA-376176
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Antigen processing-Cross presentation R-HSA-1236975
S Phase R-HSA-69242
Vpu mediated degradation of CD4 R-HSA-180534
Hedgehog 'on' state R-HSA-5632684
HIV Infection R-HSA-162906
Deubiquitination R-HSA-5688426
Host Interactions of HIV factors R-HSA-162909
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G2/M Transition R-HSA-69275
M Phase R-HSA-68886
Cellular responses to stimuli R-HSA-8953897
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of PTEN stability and activity R-HSA-8948751
Class I MHC mediated antigen processing & presentation R-HSA-983169
DNA Replication R-HSA-69306
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TCF dependent signaling in response to WNT R-HSA-201681
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
S Phase R-HSA-69242
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by NOTCH4 R-HSA-9013694
Downstream TCR signaling R-HSA-202424
Cyclin E associated events during G1/S transition R-HSA-69202
Intracellular signaling by second messengers R-HSA-9006925
Defective CFTR causes cystic fibrosis R-HSA-5678895
ABC-family proteins mediated transport R-HSA-382556
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
p53-Dependent G1 DNA Damage Response R-HSA-69563
Synthesis of DNA R-HSA-69239
Cellular responses to stimuli R-HSA-8953897
Transcriptional regulation by RUNX3 R-HSA-8878159
Infectious disease R-HSA-5663205
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of GLI1 by the proteasome R-HSA-5610780
Generic Transcription Pathway R-HSA-212436
DNA Replication Pre-Initiation R-HSA-69002
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
ER-Phagosome pathway R-HSA-1236974
Immune System R-HSA-168256
Hedgehog 'on' state R-HSA-5632684
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cellular response to chemical stress R-HSA-9711123
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Asymmetric localization of PCP proteins R-HSA-4608870
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Assembly of the pre-replicative complex R-HSA-68867
Mitotic Metaphase and Anaphase R-HSA-2555396
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
Signaling by ROBO receptors R-HSA-376176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Adaptive Immune System R-HSA-1280218
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
M Phase R-HSA-68886
Transport of small molecules R-HSA-382551
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Neddylation R-HSA-8951664
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK family signaling cascades R-HSA-5683057
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G1 phase and G1/S transition R-HSA-453279
Deubiquitination R-HSA-5688426
Mitotic Anaphase R-HSA-68882
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Programmed Cell Death R-HSA-5357801
Hedgehog 'off' state R-HSA-5610787
Interleukin-1 family signaling R-HSA-446652
Developmental Biology R-HSA-1266738
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
UCH proteinases R-HSA-5689603
Stabilization of p53 R-HSA-69541
Degradation of beta-catenin by the destruction complex R-HSA-195253
Metabolism of proteins R-HSA-392499
Apoptosis R-HSA-109581
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
RNA Polymerase II Transcription R-HSA-73857
Nervous system development R-HSA-9675108
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hh mutants are degraded by ERAD R-HSA-5362768
Axon guidance R-HSA-422475
Disorders of transmembrane transporters R-HSA-5619115
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular responses to stress R-HSA-2262752
Disease R-HSA-1643685
Signaling by WNT R-HSA-195721
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
TCR signaling R-HSA-202403
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of RAS by GAPs R-HSA-5658442
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of polyamines R-HSA-351202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Negative regulation of NOTCH4 signaling R-HSA-9604323
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular response to hypoxia R-HSA-1234174
G2/M Checkpoints R-HSA-69481
Ub-specific processing proteases R-HSA-5689880
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Hedgehog R-HSA-5358351
PCP/CE pathway R-HSA-4086400
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of AXIN R-HSA-4641257
Mitotic G2-G2/M phases R-HSA-453274
Regulation of Apoptosis R-HSA-169911
p53-Independent DNA Damage Response R-HSA-69610
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism R-HSA-1430728
G1/S Transition R-HSA-69206
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by Interleukins R-HSA-449147
Metabolism of amino acids and derivatives R-HSA-71291
Cell Cycle R-HSA-1640170
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
PTEN Regulation R-HSA-6807070
G2/M Transition R-HSA-69275
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK1/MAPK3 signaling R-HSA-5684996
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Separation of Sister Chromatids R-HSA-2467813
Vif-mediated degradation of APOBEC3G R-HSA-180585
Gene expression (Transcription) R-HSA-74160
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
FCERI mediated NF-kB activation R-HSA-2871837
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S DNA Damage Checkpoints R-HSA-69615
Interleukin-1 signaling R-HSA-9020702
Antigen processing-Cross presentation R-HSA-1236975
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Orc1 removal from chromatin R-HSA-68949
Host Interactions of HIV factors R-HSA-162909
Regulation of RUNX2 expression and activity R-HSA-8939902
Post-translational protein modification R-HSA-597592
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of DVL R-HSA-4641258
Switching of origins to a post-replicative state R-HSA-69052
ABC transporter disorders R-HSA-5619084
Signaling by NOTCH R-HSA-157118
Beta-catenin independent WNT signaling R-HSA-3858494
Transcriptional regulation by RUNX1 R-HSA-8878171
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Innate Immune System R-HSA-168249
Cell Cycle Checkpoints R-HSA-69620
RAF/MAP kinase cascade R-HSA-5673001
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of PTEN stability and activity R-HSA-8948751
Signal Transduction R-HSA-162582

Expression Atlas ENSG00000087191
NCBI gene (formerly Entrezgene) 5705
GeneCards 9552
HGNC Symbol HGNC:9552
MIM gene 601681
UniProtKB Gene Name P62195
WikiGene 5705